CN1736423A - Method for preparing externally applied medicine for feet tinea - Google Patents
Method for preparing externally applied medicine for feet tinea Download PDFInfo
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- CN1736423A CN1736423A CN 200510012705 CN200510012705A CN1736423A CN 1736423 A CN1736423 A CN 1736423A CN 200510012705 CN200510012705 CN 200510012705 CN 200510012705 A CN200510012705 A CN 200510012705A CN 1736423 A CN1736423 A CN 1736423A
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Abstract
The invention relates to a method for preparing externally applied medicine for feet tinea, wherein the medicament comprises externally used Chinese medicinal herbs with anti-inflammation and germicidal actions, bamboo vinegar stock solution with the content of 5-300 times of total weight of Chinese medicinal herbs. The preparing process comprises heating to 40-80 deg C and holding 20-60 minutes.
Description
Technical field
The present invention relates to a kind of manufacture method for the treatment of tinea pedis external used medicines such as tinea pedis.
Technical background
Tinea pedis is the infectiousness tinea pedis that superficial mycosis or fungal infection cause, about many 10 times than tinea manuum patient of this patients account for 50%～60% of tinea, and most patients suffer from tinea pedis earlier, infect hand and other position again, and primary disease south is more to be seen.The reason that the tinea pedis prevalence is high, the one, skin of sole of foot does not have glandular integumentaria, thereby lacks the fatty acid that the mould fungus inhibition ability is arranged; The 2nd, the horny layer of sufficient sole of the foot portion is thicker, and the keratoprotein in the horny layer becomes the nutrition field of mycete parasitism; The 3rd, the skin of sole of foot sweat gland is abundanter, and it is more to perspire, and causes the wet environment that helps fungus growth.Summer climate humidity, footgear make local environment sultry, and sweaty foot is difficult to volatilize, and more helps the growth and breeding of mycete.
1. local topical medicine: the antifungal medicine for external use of treatment tinea pedis has a variety of, effect is generally all good, as hospital-made ketoconazole frost, benzoic acid alcohol liquid and unguentum acidi salicylici etc., commercially available have clotrimazole ointment, Compound Flavescent Sophora and Salicylic Acid Powder, Lan Mei express Emulsion, mould gram cream, inspire confidence in fine jade emulsifiable paste etc.Erosion, sepage are arranged or when infecting between toe, cannot the strong medicine of external zest, and should first 3% boric acid solution or furacilin solution soak, treat the skin back reuse antifungal preparation that becomes dry; Infect when weighing, can add antibiotic.
2. whole body therapeutic: for the tinea pedis of stubbornness, do not having under the situation of contraindication, can oral terbinafine, itraconazole, fluconazol etc., the dosage and the course of treatment are by doctor's advice.Though tinea pedis is very high at China's sickness rate, symptom and not serious, so many patients is generally speaking itched for a short time and is promptly grabbed, and itches greatly and just controls, and does not itch and does not then control; Light when weighing when discontinuous, non-normal treatment makes tinea pedis, root does not always break yet.If want tinea pedis is cured, must arrive the skin training, regular treatment links up.In addition, keep good hygienic habit, duty is washed socks, pad, diligent foot bath, duty is changed footwear, and carries out disinfectant measure, the drying that keeps foot and footwear simultaneously, sufficient hyperhidrosis person also can spread antiperspirant such as a little alumen powders, hexamethylenamine in footwear, after a bath or after the swimming should dry foot especially toe seam.In addition, it is noted that the diabetes patient of tinea pedis does not obtain at blood glucose under the situation of fine control, tinea pedis is not easy to cure.
Summary of the invention
Technical problem to be solved by this invention provides the Chinese herbal medicine for external use manufacture method that a kind of Bamboo vinegar stock solution with bactericidal effect is solvent treatment tinea pedis.
The present invention adopts following technical scheme:
The present invention adds Bamboo vinegar stock solution in the Chinese herbal medicine for external use of traditional treatment tinea pedis with anti-inflammation and sterilization effect, wherein the addition of Bamboo vinegar stock solution be Chinese herbal medicine for external use weight 5-300 doubly, be heated to 40-80 ℃ and keep promptly making in 20-60 minute.
The present invention can add the Chinese herbal medicine for external use component of one group of weight portion among following A, B, C, D, E, F or the G in weight portion is 6000 parts Bamboo vinegar stock solution:
A group: Cortex Pseudolaricis 5-60 Herba Sophorae alopecuroidis 5-60 Fructus Cnidii 5-60 Flos Lonicerae 5-60
Radix Et Rhizoma Rhei 5-60 Rhizoma Coptidis 5-60 Radix Scutellariae 5-60 Radix Sophorae Flavescentis 5-60
Fructus Zanthoxyli 5-60 Herba Artemisiae Scopariae 5-60 Herba Taraxaci 5-60 Cortex Dictamni 5-60
Radix Salviae Miltiorrhizae 5-60 Flos Caryophylli 5-60 Fructus Gardeniae 5-60
B group: Cortex Pseudolaricis 5-60 Radix Sophorae Flavescentis 5-60 Fructus Chaenomelis 5-60 Rhizoma Atractylodis 5-60
Radix Saposhnikoviae 5-60 Herba Schizonepetae 5-60 Fructus Kochiae 5-60 Fructus Zanthoxyli 5-60
Radix Glycyrrhizae 5-60 Cortex Phellodendri 5-60 Radix Sanguisorbae 5-60
C group: Cortex Pseudolaricis 5-60 Herba Sophorae alopecuroidis 5-60 Fructus Cnidii 5-60 Rhizoma Polygonati 5-60
Herba Pogostemonis 5-60 Fructus Chaenomelis 5-60 Radix Sophorae Flavescentis 5-60 Fructus Zanthoxyli 5-60
Radix Glycyrrhizae 5-60
D group: Cortex Pseudolaricis 5-60 Herba Sophorae alopecuroidis 5-60 Flos Caryophylli 5-60 Radix Sophorae Flavescentis 5-60
Radix Et Rhizoma Rhei 5-60 Fructus Kochiae 5-60 Cortex Phellodendri 5-60 Radix Sanguisorbae 5-60
E group: Cortex Pseudolaricis 5-60 Radix Sophorae Flavescentis 5-60 Radix Angelicae Dahuricae 5-60 Fructus Gardeniae 5-60 Flos Caryophylli 5-60
F group: Cortex Pseudolaricis 5-60 Fructus Cnidii 5-60 Fructus Chaenomelis 5-60 Radix Glycyrrhizae 5-60
G group: Cortex Pseudolaricis 5-60 Rhizoma Atractylodis 5-60 Fructus Gardeniae 5-60 Radix Puerariae 5-60
Good effect of the present invention is as follows:
In the pharmaceutical compositions of the present invention:
Cortex Pseudolaricis: warm in nature, acrid in the mouth; Poisonous.Has parasite killing, itching-relieving action.Be used for the treatment that scabies is scratched where it itches.
Herba Sophorae alopecuroidis: its multiple alkaloid has very strong biological activity, mainly contain antibiotic, kill therapeutic efficiencies such as mattress, antiviral, can be developed as outer sterilization class medicine.
Fructus Cnidii: acrid in the mouth, hardship, mild toxicity.Cold expelling is arranged, dispel the wind, dampness, tonifying YANG, parasite killing, itching relieving function.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago; External treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis.
Radix Sophorae Flavescentis: property of medicine flavor is cold in nature, bitter in the mouth.Anti-inflammation, antipruritic.Heat clearing and damp drying, the parasite killing diuresis.Be used for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; The treatment of external treatment trichomonal vaginitis.
Fructus Chaenomelis: sour in the mouth, puckery, warm in nature.Relaxing muscles and tendons and activating QI and blood in the collateral is arranged, the function of stomach function regulating removing dampness.Be used for beriberi and swell and ache, bacillary dysentery, diseases such as vomiting and diarrhoea.The key stomach is held back in acid.
Fructus Zanthoxyli: external treatment skin pruritus, skin ulcer scabies.Parasite killing: be used for stomachache, vomiting ascaris due to the ascarid, and drive the ascarid effect, often join Fructus Mume.
The Radix Angelicae Dahuricae: expelling cold and dampness, understand things pain-stopping, detumescence and apocenosis.Be used for headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Rhizoma Atractylodis: drying damp and strengthening spleen, expelling wind and cold makes eye bright.Be used for distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia nyctalopia.
Radix Sanguisorbae: cooling blood for hemostasis, skin ulcer is held back in detoxifcation.Be used to have blood in stool hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus
Radix Puerariae: expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid and move back rash, yang invigorating antidiarrheal.Be used for fever caused by exogenous pathogens, the headache stiffness of the nape, thirsty quenching one's thirst, measles without adequate eruption, hematodiarrhoea is had loose bowels; Hypertension neck pain etc.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, wrist abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Fructus Gardeniae: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.It is vexed to be used for calentura, the jaundice dark coloured urine, and blood strangury and dry pain, heat in blood is told nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.The Fructus Gardeniae Preparatus cooling blood for hemostasis.Be used for heat in blood and tell nosebleed, the hematuria metrorrhagia.
Herba Artemisiae Scopariae: clearing away damp-heat, jaundice eliminating subcutaneous ulcer.Be used for the jaundice oliguria, the eczema pruritus.
Radix Salviae Miltiorrhizae: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Cortex Phellodendri: heat clearing and damp drying, pathogenic fire purging are removed and are steamed, and skin ulcer is treated in detoxifcation.Be used for damp-heat dysentery, jaundice leukorrhagia, pyretic stranguria beriberi, hectic fever due to YIN-deficiency consumptive fever, night sweat seminal emission, sore swollen toxin, eczema pruritus ， flaccidity of feet with lamenness etc.
Radix Et Rhizoma Rhei: purging heat to relax the bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.Be used for the excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, the conjunctival congestion pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle is treated skin ulcer, blood stasis amenorrhea, traumatic injury.The external treatment burn due to hot liquid or fire.
Rhizoma Polygonati: boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.Be used for weakness of the spleen and stomach, fatigue and asthenia, the xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Herba Taraxaci: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.Be used for furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Bamboo vinegar stock solution all has significantly antibacterial and bactericidal action to common dermatophytosis (trichophyton, trichophyton gypseum, alpha fungus) and deep infection fungus (Candida albicans, neogenesis cryptococcus, Aspergillus fumigatus).
When utilizing Drug therapy tinea pedis proposed by the invention, get medicine 500-6000 of the present invention gram and boil, when treating preference temperature both feet are immersed in the warm liquid 10-20 minute, every day 1-2 time, generally medication 3-5 agent can reach curative effect preferably, and the 10-20 agent can be cured.
For delivering the therapeutic effect of medicine of the present invention to the tinea pedis disease, through 100 routine tinea pedis patients are carried out clinical treatment observation, its effect is as follows:
Male patient's 69 examples wherein, female patient 31 examples, adopt medicine of the present invention wash every day sufficient morning, evening each twice, soaked 20 minutes at every turn, 2000 gram medicines are potion, potion was treated after 20 days and to be observed every day, cured 72 examples (male's 51 examples wherein, women's 21 examples), produce effects 28 examples (wherein male's 18 examples, women's 10 examples), food avoids pungent food during the treatment.
The present invention is on the basis of traditional treatment tinea pedis Chinese herbal medicine, add the pure natural product Bamboo vinegar stock solution that self has the bactericidal effect, Bamboo vinegar stock solution has substituted normally used solvent (solvent) water, because the adding of Bamboo vinegar stock solution has improved the extraction efficiency of Chinese herbal medicine and strengthened drug effect than normally used aqueous solvent.Therefore adopt medicine of the present invention that the treatment of tinea pedis disease has been obtained effect preferably.
The specific embodiment embodiment of the invention is as shown in the table:
Table 1
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 5 | 35 | 60 |
| Herba Sophorae alopecuroidis | 32 | 5 | 60 |
| Fructus Cnidii | 60 | 35 | 5 |
| Flos Lonicerae | 35 | 5 | 60 |
| Radix Et Rhizoma Rhei | 5 | 60 | 35 |
| Rhizoma Coptidis | 60 | 35 | 5 |
| Radix Scutellariae | 35 | 60 | 5 |
| Radix Sophorae Flavescentis | 5 | 40 | 60 |
| Fructus Zanthoxyli | 5 | 35 | 60 |
| Herba Artemisiae Scopariae | 60 | 5 | 35 |
| Herba Taraxaci | 35 | 60 | 5 |
| Cortex Dictamni | 60 | 35 | 5 |
| Radix Salviae Miltiorrhizae | 35 | 5 | 60 |
| Flos Caryophylli | 5 | 35 | 60 |
| Fructus Gardeniae | 60 | 35 | 5 |
Table 2
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 5 | 35 | 60 |
| Radix Sophorae Flavescentis | 35 | 60 | 5 |
| Fructus Chaenomelis | 60 | 5 | 35 |
| Rhizoma Atractylodis | 35 | 60 | 5 |
| Radix Saposhnikoviae | 5 | 60 | 35 |
| Herba Schizonepetae | 60 | 35 | 5 |
| The Fructus Kochiae | 35 | 60 | 5 |
| Fructus Zanthoxyli | 5 | 35 | 60 |
| Radix Glycyrrhizae | 60 | 5 | 35 |
| Cortex Phellodendri | 5 | 35 | 60 |
| Radix Sanguisorbae | 35 | 60 | 5 |
Table 3
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 60 | 35 | 5 |
| Herba Sophorae alopecuroidis | 35 | 5 | 60 |
| Fructus Cnidii | 5 | 60 | 35 |
| Rhizoma Polygonati | 60 | 5 | 35 |
| Herba Pogostemonis | 35 | 60 | 5 |
| Fructus Chaenomelis | 60 | 5 | 35 |
| Radix Sophorae Flavescentis | 5 | 35 | 60 |
| Fructus Zanthoxyli | 60 | 5 | 35 |
| Radix Glycyrrhizae | 35 | 60 | 5 |
Table 4
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 5 | 35 | 60 |
| Herba Sophorae alopecuroidis | 35 | 5 | 60 |
| Flos Caryophylli | 5 | 60 | 35 |
| Radix Sophorae Flavescentis | 60 | 35 | 5 |
| Radix Et Rhizoma Rhei | 60 | 5 | 35 |
| The Fructus Kochiae | 35 | 5 | 60 |
| Cortex Phellodendri | 5 | 60 | 35 |
| Radix Sanguisorbae | 35 | 60 | 5 |
Table 5:
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 35 | 5 | 60 |
| Radix Sophorae Flavescentis | 60 | 35 | 5 |
| The Radix Angelicae Dahuricae | 5 | 60 | 35 |
| Fructus Gardeniae | 35 | 5 | 60 |
Table 6
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 60 | 5 | 35 |
| Fructus Cnidii | 35 | 60 | 5 |
| Fructus Chaenomelis | 5 | 35 | 60 |
| Radix Glycyrrhizae | 35 | 5 | 60 |
Table 7
| Component | Content (ratio of weight and number) | ||
| Cortex Pseudolaricis | 5 | 35 | 60 |
| Rhizoma Atractylodis | 35 | 5 | 60 |
| Fructus Gardeniae | 60 | 35 | 5 |
| Radix Puerariae | 35 | 60 | 5 |
Claims (2)
1, a kind of manufacture method for the treatment of the tinea pedis external used medicine, it is characterized in that in the Chinese herbal medicine for external use of traditional treatment tinea pedis, adding Bamboo vinegar stock solution with anti-inflammation and sterilization effect, wherein the addition of Bamboo vinegar stock solution be Chinese herbal medicine for external use weight 5-300 doubly, be heated to 40-80 ℃ and keep promptly making in 20-60 minute.
2, a kind of manufacture method for the treatment of the tinea pedis external used medicine according to claim 1 is characterized in that can adding the Chinese herbal medicine for external use component of any one group of weight portion among following A, B, C, D, E, F or the G in weight portion is 6000 parts Bamboo vinegar stock solution:
A group: Cortex Pseudolaricis 5-60 Herba Sophorae alopecuroidis 5-60 Fructus Cnidii 5-60
Flos Lonicerae 5-60 Radix Et Rhizoma Rhei 5-60 Rhizoma Coptidis 5-60
Radix Scutellariae 5-60 Radix Sophorae Flavescentis 5-60 Fructus Zanthoxyli 5-60
Herba Artemisiae Scopariae 5-60 Herba Taraxaci 5-60 Cortex Dictamni 5-60
Radix Salviae Miltiorrhizae 5-60 Flos Caryophylli 5-60 Fructus Gardeniae 5-60
B group: Cortex Pseudolaricis 5-60 Radix Sophorae Flavescentis 5-60 Fructus Chaenomelis 5-60
Rhizoma Atractylodis 5-60 Radix Saposhnikoviae 5-60 Herba Schizonepetae 5-60
Fructus Kochiae 5-60 Fructus Zanthoxyli 5-60 Radix Glycyrrhizae 5-30
Cortex Phellodendri 5-60 Radix Sanguisorbae 5-60
C group: Cortex Pseudolaricis 5-60 Herba Sophorae alopecuroidis 5-60 Fructus Cnidii 5-60
Rhizoma Polygonati 5-60 Herba Pogostemonis 5-60 Fructus Chaenomelis 5-60
Radix Sophorae Flavescentis 5-60 Fructus Zanthoxyli 5-60 Radix Glycyrrhizae 5-60
D group: Cortex Pseudolaricis 5-60 Herba Sophorae alopecuroidis 5-60 Flos Caryophylli 5-60
Radix Sophorae Flavescentis 5-60 Radix Et Rhizoma Rhei 5-60 Fructus Kochiae 5-60
Cortex Phellodendri 5-60 Radix Sanguisorbae 5-60
E group: Cortex Pseudolaricis 5-60 Radix Sophorae Flavescentis 5-60 Radix Angelicae Dahuricae 5-60
Fructus Gardeniae 5-60
F group: Cortex Pseudolaricis 5-60 Fructus Cnidii 5-60 Fructus Chaenomelis 5-60
Radix Glycyrrhizae 5-60
G group: Cortex Pseudolaricis 5-60 Rhizoma Atractylodis 5-60 Fructus Gardeniae 5-60
Radix Puerariae 5-60
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| Application Number | Priority Date | Filing Date | Title |
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| CNB2005100127056A CN100388932C (en) | 2005-07-29 | 2005-07-29 | Method for preparing externally applied medicine for feet tinea |
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|---|---|---|---|
| CNB2005100127056A CN100388932C (en) | 2005-07-29 | 2005-07-29 | Method for preparing externally applied medicine for feet tinea |
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| CN1736423A true CN1736423A (en) | 2006-02-22 |
| CN100388932C CN100388932C (en) | 2008-05-21 |
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| CN102205079A (en) * | 2011-05-04 | 2011-10-05 | 刘军梅 | Chinese medical soaking agent for treating tinea pedis |
| CN102429990A (en) * | 2011-12-30 | 2012-05-02 | 山西紫林食品有限公司 | A foot bath vinegar prepared from vinegar and Chinese medicinal materials for deodorizing, relieving itching and treating loempe, and its preparation method |
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| CN101926876A (en) * | 2010-09-01 | 2010-12-29 | 黑龙江省亨发药业有限公司 | Traditional Chinese medicine ointment for treating psoriasis, stubborn dermatitis and pruritus, and preparation method thereof |
| CN101926876B (en) * | 2010-09-01 | 2014-03-05 | 黑龙江省亨发药业有限公司 | Traditional Chinese medicine ointment for treating psoriasis, stubborn dermatitis and pruritus, and preparation method thereof |
| CN102205079A (en) * | 2011-05-04 | 2011-10-05 | 刘军梅 | Chinese medical soaking agent for treating tinea pedis |
| CN102429990A (en) * | 2011-12-30 | 2012-05-02 | 山西紫林食品有限公司 | A foot bath vinegar prepared from vinegar and Chinese medicinal materials for deodorizing, relieving itching and treating loempe, and its preparation method |
| CN103656264A (en) * | 2013-05-17 | 2014-03-26 | 北京工商大学 | Traditional Chinese herbal medicinal foot bathing lotion added with bamboo vinegar and preparation method thereof |
| CN103356839A (en) * | 2013-07-19 | 2013-10-23 | 汤广银 | Chinese herbal compound preparation for treatment of skin diseases and its use method |
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| CN105998574A (en) * | 2016-07-13 | 2016-10-12 | 彭明见 | Special-effect medicine for treating dermatophytosis and preparing method thereof |
| CN107260867A (en) * | 2017-06-30 | 2017-10-20 | 李永建 | A kind of lotion for treating psoriasis |
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| CN109925332A (en) * | 2018-05-10 | 2019-06-25 | 周云 | A kind of composition antipruritic for antibacterial skin and its preparation method and application |
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| CN100388932C (en) | 2008-05-21 |
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