CN1679890A - Sobering up infusion granule and preparation thereof - Google Patents
Sobering up infusion granule and preparation thereof Download PDFInfo
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- CN1679890A CN1679890A CNA2005100123178A CN200510012317A CN1679890A CN 1679890 A CN1679890 A CN 1679890A CN A2005100123178 A CNA2005100123178 A CN A2005100123178A CN 200510012317 A CN200510012317 A CN 200510012317A CN 1679890 A CN1679890 A CN 1679890A
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Abstract
A sobering-up infusion is prepared from 13 Chinese-medicinal materials including haw, oyster shell, red beam, wolfberry fruit, etc through crushing, immersing, decocting, filtering, concentrating, granulating, drying and sterilizing.
Description
Technical field
The present invention relates to a kind of alcohol-decomposing powder compositions, particularly relating to a kind of is the alcohol-decomposing powder that raw material is made with the Chinese herbal medicine.
Background technology
At present China has become maximum in the world Chinese liquor production and consumption state, can not keep from drink many occasion people, and wine can bring enthusiasm, excitement, luckiness even inspiration to people, and spirits culture has been permeated various aspects such as work in us, life.But drink often to the people bring gastrointestinal upset, nausea and vomiting, irritability with mental disarrangement, uncomfortable symptom such as have a dizzy spell, even, bring various hidden danger for society and health because of excessive consumption of alcohol often causes various accidents.Be the various uncomfortable symptom that solution is drunk and brought, people have carried out many researchs and exploration, have occurred the report of products such as many beverages that relieve the effect of alcohol, sober up that utilize Chinese herbal medicine to develop, electuary in recent years, as disintoxicating product " extra large Wang Jin cup " in the market; The disclosed a kind of alcohol-decomposing beverage of Patent Office of the People's Republic of China's publication number CN1371732A in addition, it is processed by Radix Puerariae, Concha Ostreae, Poria, Rhizoma Dioscoreae, Fructus Crataegi, Semen Lablab Album, Bulbus Lilii, Semen Phaseoli, Fructus Canarii, Semen Nelumbinis, Fructus Mori, Semen Coicis, Radix Glycyrrhizae, Fructus Amomi, Flos Chrysanthemi, Fructus Momordicae, fresh Rhizoma Phragmitis, fresh Rhizoma Imperatae, Pericarpium Citri Reticulatae, Rhizoma Zingiberis Recens, Rhizoma Zingiberis, Fructus Jujubae etc.; Publication number is the infusion for relieving alcoholism and protecting liver of CN1448166A, adopts raw materials such as Radix Puerariae, Semen Hoveniae (Fructus Hoveniae), Pericarpium Citri Reticulatae, Fructus Crataegi, Stigma Maydis, Poria to make in its application; Publication number is the fast acting sobering-up and liver protecting medicine of CN1391935A, adopts raw materials such as Flos puerariae lobatae, Semen Phaseoli flower, turnip seed, Radix Puerariae, Concha Ostreae, Fructus Citri Sarcodactylis, CitrusaurantiumL.Var.amara Engl., Flos Chimonanthi Praecocis, Flos Albiziae to make in its application; Or the like.Above product or technical scheme mainly are to utilize the sober-up function of Chinese herbal medicine, but different its sober-up functions of prescription that relieve the effect of alcohol often have very big difference, these sobering preparations often adopt traditional decoction simultaneously, concentrate, technologies such as drying are processed, thereby make the effective ingredient in the herbal raw material run off serious, make utilization rate reduce, cause the effect of relieving the effect of alcohol to have a greatly reduced quality, can not effectively remove and alleviate the vomiting after drinking, dizziness headache, stomach such as feels bad at uncomfortable symptom, particularly to second day lasting discomfort after the excessive consumption of alcohol, existing alcohol-decomposing beverage can not demonstrate fully its specially good effect.
Summary of the invention
Alcohol-decomposing powder of the various uncomfortable symptoms that occur after the object of the invention provides a kind of utilization rate of active components height, can effectively remove and alleviates and drinks and preparation method thereof is to overcome the deficiencies in the prior art.
For realizing the object of the invention, adopt the raw material components of following portions by weight ratio:
Fructus Crataegi 30～45 Fructus Citri Sarcodactylis 10～20 Concha Ostreaes 30～40
Semen Phaseoli 60～100 Semen Hoveniae (Fructus Hoveniae)s 60～80 Fructus Lycii 10～20
Fructus Gardeniae 20～25 Poria 40～45 Herba Moslaes 30～40
Fructus Mori 60～90 Rhizoma Alpiniae Officinarums 15～20 Radix Puerariaes 40～70
Pericarpium Citri Reticulatae 20～30.
Above-mentioned each component preferred weight portion rate is:
Fructus Crataegi 30～40 Fructus Citri Sarcodactylis 10～15 Concha Ostreaes 35～40
Semen Phaseoli 70～100 Semen Hoveniae (Fructus Hoveniae)s 65～80 Fructus Lycii 10～15
Fructus Gardeniae 20～25 Poria 40～45 Herba Moslaes 35～40
Fructus Mori 60～80 Rhizoma Alpiniae Officinarums 15～20 Radix Puerariaes 40～60
Pericarpium Citri Reticulatae 25～30.
Realize the preparation method of the alcohol-decomposing powder of proportioning of the present invention, it may further comprise the steps:
A. take by weighing each decoction pieces raw material at first according to the following number of weight ratio:
Fructus Crataegi 30～45 Fructus Citri Sarcodactylis 10～20 Concha Ostreaes 30～40
Semen Phaseoli 60～100 Semen Hoveniae (Fructus Hoveniae)s 60～80 Fructus Lycii 10～20
Fructus Gardeniae 20～25 Poria 40～45 Herba Moslaes 30～40
Fructus Mori 60～90 Rhizoma Alpiniae Officinarums 15～20 Radix Puerariaes 40～70
Pericarpium Citri Reticulatae 20～30;
Above-mentioned each decoction pieces raw material that takes by weighing is mixed, be crushed to 10～200 orders, put into the vacuum Decocting pot then and soaked 0.5～1 hour;
B. the decoction pieces raw material after soaking in the above-mentioned vacuum Decocting pot is heated and evacuation, and under 45 ℃～55 ℃ boiling points, decocted 0.5～1 hour, obtain a decocting liquid and a filtering residue after the filtration; Wherein 45 ℃～55 ℃ the pairing negative pressure of boiling point is 9.56Kpa～15.70Kpa;
C. under 45 ℃～55 ℃ boiling points, decocted 0.2～0.5 hour after an above-mentioned filtering residue being added water, obtain secondary decocting liquid and secondary filtering residue after the filtration;
D. under 45 ℃～55 ℃ boiling points, decocted 0.2～0.4 hour after the secondary filtering residue being added water, obtain decocting liquid after the filtration three times;
E. each time decocting liquid of making more than inciting somebody to action mixes, filters, and is concentrated into the oleo stock of relative density 1.4～1.5 under 45 ℃～55 ℃ boiling points;
F. in the oleo stock that the e step is made, add sodium benzoate, stir and make granule after spray;
G. will add flavoring agent behind the above-mentioned particle drying, stir, packing, alcohol-decomposing powder of the present invention is made in sterilization.
The consumption of above-mentioned flavoring agent accounts for 10%～30% of dried particles, mainly is to improve and improve mouthfeel of the present invention, and what of its consumption are not as a limitation of the invention, and wherein flavoring agent comprises sugar or sweeting agent, citric acid or malic acid, essence.
Cobalt 60 irradiation-sterilizes are taked in above-mentioned sterilization.
Traditional Chinese medical science outline, wine is the thing of burning hot noxious dampness, polydipsia is vomiting then, says in " element is asked the most pure virginity main point opinion ": " all contrary rushing to all belong to fire ".As seen on the burning hot inflammation, burning hot upper punch is sent out to feeling sick after drinking, vomitting.The humidity hysteresis the intestines and stomach, clear QI failing to ascend, turbid QI failing to descend, then chest and diaphragm is full vexed, and gastral cavilty is felt bad, anorexia, body is felt bad, it is then thirsty that hinder in Tianjin, attacks then headache, " deficient earth being subjugated by wood " liver-fire upper punch on the damp and hot up women's head-ornaments of arteries and veins that follow the positive bright footpath of foot, send out to dizzy, all be that disease burning hot, noxious dampness resembles, control with nourishing YIN and clearing away heat, drying damp and strengthening spleen method, to dissolve it.
The inventor is by the research and the long-term practical experience of the Chinese herbal medicine property of medicine, and by the theory of Chinese medical science prescription, adopting Fructus Mori, Radix Puerariae is monarch.Fructus Mori is sweet in flavor and cold in property, Yin-nourishing and body fluid promoting, diuretic gas, promoting the production of body fluid to quench thirst.Compendium of Material Medica is said: the Fructus Mori alcoholic intoxication, and diuretic gas, detumescence has the function of relieving the effect of alcohol greatly.Spleen, stomach footpath are returned in the sweet cold of Radix Puerariae nature and flavor, get the property of its cool profit, but promoting the production of body fluid to quench thirst, the energy alcoholic intoxication, Gu is used it more.Say as " property of medicine opinion ": Radix Puerariae can be controlled a day row and go up gas, vomiting, and whetting the appetite, the principal solution alcoholism ends excessive thirst." the southern regions of the Yunnan Province book on Chinese herbal medicine " said: Radix Puerariae is separated middle wine pyretic toxicity." medicine origin " cloud: Radix Puerariae its with having four: quench the thirst one also, relieve the effect of alcohol two also.Reuse Fructus Mori, Radix Puerariae, focus on and get its cold and cool property, the energy Yin-nourishing and body fluid promoting, strong water can be made fire with heat clearing away consolidating YIN, cloudy solid then water, and heat clearly then consumes the moon and has no way of.This i.e. " element is asked the most pure virginity main point opinion " strengthening renal yin to inhibit predominant yang, with the method for system sunlight, and fiery must the loosing of going up heat that alcoholism is caused, interior strongly fragrant hot must falling is to reach the antialcoholic purpose.
Minister is with Semen Phaseoli, Poria, Herba Moslae.The sweet acid of Semen Phaseoli is slightly cold, and diuretic dries, and claims its " main cold and heat are pined for quenching one's thirst, diuresis, emesis is contrary " in " not Lu ", can make damp and hot alcoholism ooze profit and clear up.The Poria nature and flavor are sweet flat, energy promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach.Says in " property of medicine opinion ": the Poria appetizing, preventing or arresting vomiting is contrary, and, symptoms such as gastral cavilty feel bad, anorexia completely vexed to the spleen and stomach being stranded by dampness after drinking, chest and diaphragm have mitigation greatly.Herba Moslae is got itself and middle removing dampness, the effect of line water detumescence, and it is wet that taste are liked dry evil, and Herba Moslae cures mainly internal injury in wet, headache, vomiting can make after drinking taste hinder in the symptom of damp and be alleviated.The combination of Semen Phaseoli, Poria, Herba Moslae three flavor ministerial drugs can make after drinking the taste damp change, QI movement being in harmonious way, taste rehabilitation, gastric qi and falling.
Assistant is with Fructus Gardeniae, the Semen Hoveniae (Fructus Hoveniae) of heat-clearing and toxic substances removing, and the Fructus Lycii of YIN nourishing and YANG strengthening and preventing or arresting vomiting, eliminating turbid pathogen with aromatics, the Pericarpium Citri Reticulatae of circulation of qi promoting spleen invigorating, Rhizoma Alpiniae Officinarum make that preventing or arresting vomiting is told, the effect of stomach function regulating further strengthens.
Make with Fructus Crataegi, Fructus Citri Sarcodactylis, Concha Ostreae.The Fructus Crataegi strengthening the spleen and stomach, Fructus Citri Sarcodactylis liver-smoothing, qi-regulating, stomach function regulating removing dampness, arresting vomiting by invigorating the stomach.Concha Ostreae is calmed the nerves, nourishing liver-YIN, and the liver-yang of diving, system gastric acid ends stomachache, and hot-tempered after drinking with controlling, distending pain in the head is dizzy, obnubilation.
Use preparation of the present invention before wine, in the wine or carried out crowd's test after drinking respectively, test shows, before wine, take the present invention, flushing, dizzy, the headache that can make that the back of drinking at ordinary times occurs, uncomfortable in chest, the stagnation of QI, vomiting and nausea, quench one's thirst, stomach is felt bad etc., and uncomfortable symptom does not occur; The wine neutralization is taken after drinking, and the various uncomfortable symptom that the back of drinking is occurred obtains rapidly removing; Test shows that also the present invention can significantly improve examination receptor's drinking amount, after taking the present invention, drinks when surpassing nearly one times at ordinary times capacity for liquor, and various uncomfortable symptoms did not occur in second day.
The present invention takes the result and shows, has remarkable characteristic in following several respects:
1. various symptoms that occur at human body after the excessive consumption of alcohol, owing to adopt above-mentioned all medicine phases 5, property of medicine complementation, drug action is obviously heightened, nourishing YIN and clearing away heat and drying damp and strengthening spleen two is looked at each other, make fire lowering and heat removing, turbid damp must be changed, turbid the falling of clear liter, mechanism of qi is unobstructed, can make dizzy that excessive consumption of alcohol causes, headache, uncomfortable in chest, the stagnation of QI, vomiting and nausea, quench one's thirst, the all diseases of alcoholism such as obnubilation are removed rapidly, and produce effects is fast, and can reach relieving alcoholism and protecting the liver, clear away heart-fire and allay excitement, the chest stuffiness relieving of regulating the flow of vital energy, the resolving depression of being amusing, invigorating the stomach and promoting digestion, effects such as promoting the production of body fluid to quench thirst, especially for the back second day lasting discomfort of drinking, before wine, in the wine or after taking the present invention after drinking, above-mentioned symptom does not occur, effect stability is taken the back and is not had other untoward reaction.
2. owing to will decoct after each decoction pieces raw material fragmentation, the cell wall in the raw material is broken up in a large number, effective ingredient is easy to separate out, and has improved utilization rate of active components, has reduced cost of manufacture of the present invention simultaneously.
3. it is serious that traditional decocting method makes that the medium-height grass the effective elements of the medicine runs off, and utilization rate reduces, and causes the effect of relieving the effect of alcohol to have a greatly reduced quality.And the present invention takes to decoct under negative pressure state and concentrate, and decocting liquid is seethed with excitement at a lower temperature, thereby can keep the active effective ingredient in the Chinese herbal medicine to greatest extent, thereby can bring into play the effect of relieving the effect of alcohol of the present invention to greatest extent.
4. because the present invention be a medicine-food two-purpose, except that electuary, also can be made into tablet, capsule or etc. multiple dosage form, the user can choose at random suitable oneself dosage form, mouthfeel, color and luster are easily accepted by the people, and be easy to carry, takes safety, has no side effect.
Experimental study result statistics of the present invention shows that 156 men and women take before drinking, make capacity for liquor increase by 1/3～1/2 than original; Wherein 137 famous-drinks occur dizzy, headache, uncomfortable in chest, the stagnation of QI, vomiting and nausea after drinking, quench one's thirst, the men and women of symptom such as obnubilation takes, and above symptom obtains removing very soon, and onset time was at 2～3 minutes; Wherein the men and women of the second day after drinking various uncomfortable symptoms of appearance of 112 famous-drinks takes, and above symptom did not occur in second day.
Part typical case of the present invention is as follows:
1. Zhao, the man, 37 years old, the cadre of North China Pharmaceutical Factory only can drink about three liang of wine, take the present invention after, drink half jin of wine and do not feel to feel bad.
2. Zhang, man, 36 years old, the cadre of North China Pharmaceutical Factory, readme is former drinks three liang and has a brick in one's hat after drinking, and feels bad, and about 15 grams of the present invention are taken in the back at every turn before drinking, drink three liang of wine and uncomfortable sensation do not occur, also do not feel after drinking for half jin to feel bad, also do not occur malaise symptoms in second day.
3. Dong, the man, 36 years old, the cadre of North China Pharmaceutical Factory, take the present invention after, do not feel bad after drinking, and capacity for liquor obviously increases.
4. Lu, the man, 40 years old, the always black cat restaurant manager in Shijiazhuang, dinner party at ordinary times is extremely many, takes the present invention for many years, and he or she master states: after taking the present invention, three, four liang of numbnesss after drinking, seven, eight liang are not had the phenomenon of feeling bad after drinking;
5. Zhang, the man, 48 years old, the cadre of North China Pharmaceutical Factory, it is just flushing to drink at ordinary times, feel bad, vomiting, about 10 grams of the present invention are taken in the back at every turn before drinking, and drinkable two liang of wine and nothing are felt bad sensation; Occur after drinking flushing, feel bad, take the present invention when symptom is felt bad in vomiting etc., above-mentioned symptom disappeared in about 2～3 minutes.
6. Zhu, the man, 35 years old, the workman of North China Pharmaceutical Factory, three liang of wine are just liquor-saturated at ordinary times, take the present invention before drinking at every turn after, it is liquor-saturated and do not have and feel bad sensation to drink four, five liang of wine.
Xu certain, the man, 37 years old, the workman of North China Pharmaceutical Factory only can drink three liang of wine at ordinary times, on October 9th, 2004, a.p hot water was taken after mixing it with water behind the present invention 15 gram, drank half jin of 60 degree Chinese liquor and uncomfortable symptom do not occur, and sense of discomfort was not arranged in second day yet; Drink the present invention's 20 grams when malaise symptoms occurring after drinking, uncomfortable symptom disappears at once.
8. Zhang, the man, 32 years old, the workman of North China Pharmaceutical Factory though can drink at ordinary times, felt to feel bad after drinking, on October 9th, 2004 a.p hot water take after mixing it with water take the present invention's 20 grams after, drink half jin of 60 degree Chinese liquor, feel comfortable after drinking, do not have in second day and to feel bad sensation.
Section certain, the man, 39 years old, the workman of North China Pharmaceutical Factory only can drink three liang of wine at ordinary times, on October 9th, 2004, a.p hot water was taken after mixing it with water behind about 20 grams of the present invention, drank nearly half jin of 60 degree Chinese liquor, did not feel bad sensation with all having in second day after drinking.
10. in certain, the man, 59 years old, the cadre of North China Pharmaceutical Factory, only can drink three liang of wine at ordinary times, before wine, wine neutralization all took the present invention after drinking, once consumption was 10～20 grams, the no discomfort of drinking after taking before the wine, when appearring in wine neutralization after drinking, uncomfortable symptom takes the present invention, symptom is removed at once, does not also occur feeling bad sensation in second day, and drinking amount doubles.
For further specifying the present invention, the invention will be further described below in conjunction with specific embodiment:
Embodiment 1: take by weighing each decoction pieces raw material by following weight: Fructus Crataegi 30g, Fructus Citri Sarcodactylis 10g, Concha Ostreae 40g, Semen Phaseoli 100g, Semen Hoveniae (Fructus Hoveniae) 80g, Fructus Lycii 10g, Fructus Gardeniae 20g, Poria 40g, Herba Moslae 30g, Fructus Mori 80g, Rhizoma Alpiniae Officinarum 20g, Radix Puerariae 40g, Pericarpium Citri Reticulatae 30g, then above-mentioned each decoction pieces raw material that takes by weighing is operated according to the technical process of discussing in this description summary of the invention, can be produced alcohol-decomposing powder of the present invention.
Other embodiment difference from Example 1 of the present invention sees the following form:
Unit: (g)
| Fructus Gardeniae | ????20 | ????25 | ????20 | ????23 | ????22 | ????20 | ????25 | ????20 | ????20 | ????25 |
| Poria | ????40 | ????45 | ????43 | ????45 | ????43 | ????40 | ????45 | ????40 | ????40 | ????45 |
| Herba Moslae | ????30 | ????40 | ????35 | ????35 | ????40 | ????33 | ????36 | ????30 | ????35 | ????40 |
| Fructus Mori | ????60 | ????90 | ????70 | ????65 | ????75 | ????80 | ????85 | ????90 | ????60 | ????80 |
| Rhizoma Alpiniae Officinarum | ????15 | ????20 | ????18 | ????15 | ????17 | ????15 | ????20 | ????20 | ????15 | ????20 |
| Radix Puerariae | ????40 | ????70 | ????45 | ????50 | ????55 | ????60 | ????65 | ????70 | ????40 | ????60 |
| Pericarpium Citri Reticulatae | ????20 | ????30 | ????25 | ????27 | ????23 | ????27 | ????30 | ????20 | ????25 | ????30 |
Except that the described method of above embodiment, realize that decoction process in the preparation method of the present invention also can take first high temperature, the cryogenic method in back, decocted 0.5～1 hour under 105 ℃～108 ℃ boiling temperatures as in the b of this description summary of the invention step, taking, in c step and d step, under 70～80 ℃ of boiling temperatures, decocted respectively 0.3～1 hour then, its effect one is the active effective ingredient that as far as possible keeps to greatest extent in the Chinese herbal medicine, the 2nd, can under high-temperature high-pressure state, sterilize to decocting thing.
The present invention also can take wet granulation, after the oleo stock that is about to above-mentioned relative density 1.4～1.5 adds sugar or sweeting agent, citric acid or flavoring agents such as malic acid, essence, stirs, and granulates, and alcohol-decomposing powder of the present invention is made in oven dry.
Because each component of the present invention is the medicine-food two-purpose composition, thus above-mentioned electuary can be added also that the feed product be made the confection that relieves the effect of alcohol, the cookies that relieves the effect of alcohol, alcohol-decomposing beverage etc.
The present invention also can take after directly adding flavoring agent after the decoction pieces raw material pulverizing, packing, and Bag tea for sobering one for drinking wine is made in sterilization.
Electuary instructions of taking of the present invention is: before the wine, in the wine or take after drinking all can, warm boiled water, each 10～30 grams of common dose.Because each component of the present invention is the dual-purpose composition of natural medicine-food, thereby excessive use can not damage human body, and safe in utilization, have no side effect, and be ideal natural alcohol-decomposing beverage, be suitable for the various crowds of drinking, easy to utilize.
Claims (5)
1. alcohol-decomposing powder is characterized in that it is made by the raw material of following portions by weight ratio:
Fructus Crataegi 30～45 Fructus Citri Sarcodactylis 10～20 Concha Ostreaes 30～40
Semen Phaseoli 60～100 Semen Hoveniae (Fructus Hoveniae)s 60～80 Fructus Lycii 10～20
Fructus Gardeniae 20～25 Poria 40～45 Herba Moslaes 30～40
Fructus Mori 60～90 Rhizoma Alpiniae Officinarums 15～20 Radix Puerariaes 40～70
Pericarpium Citri Reticulatae 20～30.
2. alcohol-decomposing powder according to claim 1 is characterized in that described each raw material preferred weight portion rate is:
Fructus Crataegi 30～40 Fructus Citri Sarcodactylis 10～15 Concha Ostreaes 35～40
Semen Phaseoli 70～100 Semen Hoveniae (Fructus Hoveniae)s 65～80 Fructus Lycii 10～15
Fructus Gardeniae 20～25 Poria 40～45 Herba Moslaes 35～40
Fructus Mori 60～80 Rhizoma Alpiniae Officinarums 15～20 Radix Puerariaes 40～60
Pericarpium Citri Reticulatae 25～30.
3. preparation method that realizes the alcohol-decomposing powder of the described proportioning of claim 1, its feature may further comprise the steps:
A. at first will mix, be crushed to 10～200 orders, put into the vacuum Decocting pot then and soaked 0.5～1 hour by each decoction pieces raw material that the described proportioning of claim 1 takes by weighing;
B. the decoction pieces raw material after soaking in the above-mentioned vacuum Decocting pot is heated and evacuation, and under 45 ℃～55 ℃ boiling points, decocted 0.5～1 hour, obtain a decocting liquid and a filtering residue after the filtration;
C. under 45 ℃～55 ℃ boiling points, decocted 0.2～0.5 hour after an above-mentioned filtering residue being added water, obtain secondary decocting liquid and secondary filtering residue after the filtration;
D. under 45 ℃～55 ℃ boiling points, decocted 0.2～0.4 hour after the secondary filtering residue being added water, obtain decocting liquid after the filtration three times;
E. each time decocting liquid of making more than inciting somebody to action mixes, filters, and is concentrated into the oleo stock of relative density 1.4～1.5 under 45 ℃～55 ℃ boiling points;
F. in the oleo stock that the e step is made, add sodium benzoate, stir and make granule after spray;
G. will add flavoring agent behind the above-mentioned particle drying, stir, packing, alcohol-decomposing powder of the present invention is made in sterilization.
4. the preparation method of alcohol-decomposing powder according to claim 3 is characterized in that described flavoring agent comprises sugar or sweeting agent, citric acid or malic acid, essence.
5. the preparation method of alcohol-decomposing powder according to claim 3 is characterized in that described sterilization takes cobalt 60 irradiation-sterilizes.
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