CN1662217A - 多步化妆品有益效果粉底套盒及相关方法 - Google Patents
多步化妆品有益效果粉底套盒及相关方法 Download PDFInfo
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- CN1662217A CN1662217A CN038140764A CN03814076A CN1662217A CN 1662217 A CN1662217 A CN 1662217A CN 038140764 A CN038140764 A CN 038140764A CN 03814076 A CN03814076 A CN 03814076A CN 1662217 A CN1662217 A CN 1662217A
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
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Abstract
本发明涉及适于以多步面部粉底产品涂敷的化妆品套盒,其中该套盒包括:1)第一组合物,其包含:a)安全有效量的第一化妆品有益剂;和b)第一美容可接受载体;和2)第二组合物,其包含:a)安全有效量的一种或多种折射指数大于约2.0的着色剂;和b)第二美容可接受载体;其中所述第二组合物在所述第一组合物之后被局部涂敷于面部皮肤上。
Description
发明领域
本发明涉及适于用作多步面部粉底产品的化妆品套盒。具体地讲,该化妆品套盒包括至少两种局部并相继涂敷到面部皮肤上的组合物。
发明背景
由于化妆品有益剂掺入到有色化妆品产品中,因此这种试剂可局部涂敷于人类皮肤上,这在皮肤美容护理领域是熟知的。有许多可以这种方式涂敷到皮肤上用于各种目的的有益剂,这些有益剂包括,但不限于,吸收剂、抗痤疮活性物质、止汗剂活性物质、抗皱纹活性物质、人工晒黑剂、收敛剂、成膜剂、亲水调理剂、疏水调理剂、散光剂、脱屑剂、亮肤剂、皮肤抚慰/愈合剂、皮肤增稠剂、防晒活性物质、维生素化合物、减少黄色的颗粒、减少红色的颗粒,以及它们的组合。然而,当这些活性物质中的任何一种掺入有色化妆品中时,都有一个共同的问题出现。具体地讲,可被掺入到有色化妆品中的活性物质的量受许多参数的限制,这些参数包括,但不限于,溶解度、皮肤感觉、保持产生提供愉快的美容涂敷体验的固液比的能力。
申请者意外地发现,通过使用化妆品套盒有可能增加有效递送至皮肤的化妆品有益剂的量,所述套盒包括包含安全有效量的化妆品有益剂和合适载体的第一组合物,和包含一种或多种高折射率着色剂和着色剂载体的第二组合物。申请者还发现,第一次涂敷可改善染色的第二组合物的涂敷性质。
不受理论的限制,申请者相信这种多组合物的方法使得活性成分递送的效率得到改善,这是通过将皮肤活性有益效果功能从赋予皮肤颜色的主要功能中分离开来实现的。
发明概述
本发明涉及适于以多步面部粉底产品涂敷的化妆品套盒,其中该套盒包括:
1.第一组合物,其包含:
a.安全有效量的第一化妆品有益剂;和
b.第一美容可接受载体;和
2.第二组合物,其包含:
a.安全有效量的一种或多种折射指数大于约2.0的着色剂;和
b.第二美容可接受载体;
其中所述第二组合物在所述第一组合物之后被局部涂敷于面部皮肤上。本发明还涉及为了有效递送满意的面部粉底产品至使用者的面部皮肤而使用该套盒的方法。
发明详述
本发明涉及适于以多步面部粉底产品涂敷的化妆品套盒。该套盒的基本组分将在下面描述。还包括可用于本发明实施方案中的各种任选和优选组分的非排除性描述。
本文所用的“安全有效量”是指化合物、组分或组合物(当适用时)的量足以引起显著的积极效果(例如,提供显著的美容有益效果),但其量又足够的低以避免严重的副作用(例如,不适当的毒性或过敏反应),即在合理的医学判断范围内提供合理的有益效险比。
本文所用的“化妆品有益剂”是指为其所涂敷的表面,优选皮肤,赋予美学特征的化合物、物质和/或活性物质。
本发明可包含、由或基本上由本文所述的任何必要或任选成分、和/或限制组成。
除非另外指明,所有百分比和比率均以重量单位计。除非另外指明,所有百分比都是基于总组合物计。
所有摩尔量都是重均分子量,并以克/摩尔的单位给出。
除非另外指明,所有成分含量都不包括溶剂、副产物或其它可能存在于市售原料中的杂质。
除非另外指明,所有测量均在大约为22.8℃(73°F)的环境室温下进行。
本文所提到的所有文件,包括专利、专利申请和印刷出版物,在本公开内容中均全文引入以供参考。
化妆品套盒
本发明的化妆品套盒包括包含安全有效量的第一化妆品有益剂和第一美容可接受载体的第一组合物,和包含安全有效量的一种或多种折射指数大于约2.0的着色剂和第二美容可接受载体的第二组合物,其中第二组合物在第一个组合物之后被局部涂敷于面部皮肤上。
第一组合物
为了改善皮肤的状态,将目前受权利要求书保护的套盒的第一组合物局部涂敷于使用者的面部皮肤上。涂敷第一组合物所提供的一个有益效果是使皮肤表面为涂敷光滑、看起来自然、和美观愉悦的彩色层做好准备,以获得消费者可接受的面部彩妆产品。涂敷第一组合物可提供的另一个有益效果是递送一种或多种第一化妆品有益剂至面部皮肤。因此第一组合物使皮肤表面为涂敷高折射率的带色第二组合物做好准备。据信这种表面准备通过第一化妆品有益剂沉积和粘附在皮肤上来实现。然而,预期相同或类似的化妆品有益剂可包含在第二组合物或任何其它相继涂敷于皮肤上并用套盒包装的附加组合物中。适合的化妆品剂包括但不限于选自如下物质的那些:吸收剂、抗痤疮活性物质、止汗剂活性物质、抗皱纹活性物质、人工晒黑剂、收敛剂、成膜剂、亲水调理剂、疏水调理剂、散光剂、脱屑剂、亮肤剂、皮肤抚慰/愈合剂、皮肤增稠剂、防晒活性物质、维生素化合物,以及它们的组合。
在本发明的优选实施方案中,第一和/或第二组合物包含按组合物的重量计约0.1%至约60.0%的化妆品有益剂,无论它是在第一还是第二组合物中。实际上,甚至更优选的有益剂用量(按优选性增加的顺序)按组合物的重量计为约0.5%至约50.0%、0.5%至约40.0%、0.5%至约35.0%、和0.5%至约30.0%。适合的化妆品有益剂包括但不限于下列的那些。
吸收剂
本发明的组合物可包含一种或多种吸收剂作为化妆品有益剂。这些吸收剂可用于实现通常存在于皮肤上的各种流体的吸收,如汗液、油和/或皮脂。适合的吸收剂包括,但不限于,二氧化硅、硅酸盐、聚丙烯酸酯、交联硅氧烷、交联烃、活性炭、淀粉基物质(例如玉米淀粉(局部用淀粉)、滑石、米淀粉、燕麦淀粉、木薯淀粉、马铃薯淀粉、豆淀粉、大豆淀粉、芜菁淀粉)、微晶纤维素(如Avicel)、辛烯基琥珀酸铝淀粉(由National Starch & Chemical Co.以DryFloPure、Dry FloXT、Dry FloPC、和/或Dry FloAF(无铝级)出售)、高岭土、硅酸钙、非晶形二氧化硅、碳酸钙、碳酸镁、或碳酸锌以及它们的混合物。可用于本发明的硅酸盐和碳酸盐的某些具体实施例在Van Nostrand Reinhold的Encyclopedia ofChemistry,第四版,(1984)第155、169、556和849页中更完整地说明。
抗痤疮活性物质
可用作本发明化妆品有益剂的抗痤疮活性物质的实施例包括,但不限于,角质层分离剂如水杨酸(邻羟基苯甲酸)、水杨酸衍生物如5-辛酰基水杨酸和间苯二酚;类视黄醇如视黄酸及其衍生物(例如,顺式和反式);含硫D和L氨基酸及其衍生物和盐,尤其是它们的N-乙酰基衍生物,其优选的实施例是N-乙酰基-L-半胱氨酸;硫辛酸;抗生素和杀菌剂如过氧化苯甲酰、羟甲辛吡酮、四环素、2,4,4′-三氯-2′-羟基二苯醚、3,4,4′-三氯二苯基脲、壬二酸及其衍生物、苯氧基乙醇、苯氧基丙醇、苯氧基异丙醇、乙酸乙酯、克林霉素和甲氯环素;sebostats如类黄酮;和胆汁盐如鲨胆甾醇硫酸盐及其衍生物、去氧胆酸盐和胆酸盐。
止汗剂活性物质
止汗剂活性物质也可作为化妆品有益剂包含于本发明的组合物中。适合的止汗剂活性物质包括收敛剂金属盐,尤其是铝、锆和锌的无机盐和有机盐,以及它们的混合物。尤其优选的是含铝和/或含锆物质或盐,如卤化铝、水合氯化铝、羟基卤化铝、卤氧化锆、羟基卤氧化锆以及它们的混合物。
抗皱和抗皮肤萎缩活性物质
可用作本发明化妆品有益剂的抗皱和抗皮肤萎缩活性物质的实施例包括,但不限于,视黄酸及其衍生物(例如,顺式和反式);视黄醇;视黄酯;烟酰胺及其衍生物;含硫的D和L氨基酸及其衍生物和盐,尤其是N-乙酰基衍生物,其优选的实施例是N-乙酰基-L-半胱氨酸;硫醇,例如乙烷硫醇;萜烯醇(例如,金合欢醇);羟基酸、植酸、硫辛酸;溶血磷脂酸,α-羟基酸(例如,乳酸和乙醇酸),β-羟基酸(例如水杨酸)和蜕皮剂(例如,苯酚等)。
人工晒黑剂活性物质和促进剂
可用于本发明组合物的人工晒黑活性物质和促进剂的实施例包括,但不限于,二羟基丙酮、酪氨酸、酪氨酸酯如酪氨酸乙酯,和二氧磷基-DOPA。
收敛剂
本发明的组合物可包含收敛剂。收敛剂用于收缩皮肤的毛孔。适合的收敛剂包括,但不限于,丁香油、药用拟层孔菌提取物、绣线菊提取物、薄荷醇、樟脑、桉树油、丁子香酚、乳酸薄荷酯、金缕梅馏出液、铝盐、丹宁酸、乙醇以及它们的组合。
成膜剂
适用于本套盒组合物的成膜剂的实施例包括:
a)硫聚酯树脂,例如AQ硫聚酯树脂,如AQ29D、AQ35S、AQ38D、AQ38S、AQ48S和AQ55S(购自EastmanChemicals);
b)聚乙酸乙烯酯/聚乙烯醇聚合物,如购自Air Products的Vinex树脂,包括Vinex 2034、Vinex 2144和Vinex2019;
c)丙烯酸树脂,包括购自National Starch的商品名为“Dermacryl”的水可分散丙烯酸树脂,包括DermacrylLT;
d)聚乙烯吡咯烷酮(PVP),包括Luviskol K17、K30和K90(购自BASF)、水溶性PVP共聚物,包括PVP/VA S-630和W-735、和PVP/二甲氨基甲基丙烯酸乙酯共聚物,如购自ISP的共聚物845和共聚物937,以及其它PVP聚合物,其由E.S.Barabas公开于“Encyclopedia of PolymerScience and Engineering”,第2版,第17卷,第198至257页中;
e)高分子量聚硅氧烷,如聚二甲基硅氧烷和有机取代的聚二甲基硅氧烷,尤其是粘度大于约50,000mPas的那些聚硅氧烷;
f)粘度大于约50,000mPas的高分子量烃聚合物;
g)硅氧烷-丙烯酸酯共聚物,包括VS-70(3M)、SA-70(3M)、KP-545(Shin-Etsu);
h)有机硅氧烷,包括有机硅氧烷树脂、流体二有机聚硅氧烷聚合物和硅氧烷酯蜡;
i)聚氨酯,包括购自Alzo,Corp.的Polyderm系列聚合物;和
j)疏水丙烯酸酯共聚物,包括丙烯酸酯/烷基甲基丙烯酸酯共聚物Lipacryl(Rohm & Haas)或它的乳化、水可分散形式Allianz OPT(ISP)。
这些聚合物和包含它们的化妆品组合物的实施例可存在于1996年10月31日公布的PCT公开WO96/33689;1997年5月15日公布的WO97/17058;和1996年4月9日授予Castrogiovanni等人的美国专利5,505,937中。适用于本文的其它成膜聚合物包括含水乳液中的水不溶性聚合材料和水溶性成膜聚合物,其描述于1998年5月7日公布的PCT公开WO98/18431中。粘度大于约50,000mPas的高分子量烃聚合物的实施例包括聚丁烯、聚丁烯对苯二酸酯、聚癸烯、聚环戊二烯和类似的直链和支链高分子量烃。
优选的成膜聚合物包括有机硅氧烷树脂,包括R3SiO1/2“M”单元、R2SiO“D”单元、RSiO3/2“T”单元、SiO2“Q”单元,这些单元互相成一定比例,以满足RnSiO(4-n)/2的关系,其中n值为1.0至1.50,且R为甲基。注意由于加工的原因在树脂结构中存在少量的高至5%的硅烷醇或烷氧基官能度。有机硅氧烷树脂必须在约25℃下为固体,且具有约1,000至约10,000克/摩尔的分子量。树脂可溶解于有机溶剂,如甲苯、二甲苯、异链烷烃和环硅氧烷或挥发性载体,这意味着树脂不是完全交联,这样会使树脂不溶于挥发性载体。尤其优选的是包含重复一官能或R3SiO1/2的“M”单元和四官能或SiO2的“Q”单元,另外被称为“MQ”树脂的树脂,其公开于1994年7月19日公布的Krzysik的美国专利5,330,747中。在本发明中,“M”和“Q”功能单元的比率优选为约0.7,n值为1.2。有诸如这些的有机硅氧烷树脂是市售的,如购自Wacker Silicones Corporationof Adrian Michigan的Wacker 803和804及购自GeneralElectric Company的G.E.1170-002。
其它用于增强耐磨性或耐转移性的物质包括三甲基化二氧化硅。适合的这种类型的二氧化硅和包含它们的化妆品组合物描述于授予Brieva等人的美国专利5,800,816。
亲水调理剂
本发明的化妆品有益剂也可以是一种或多种亲水调理剂。亲水调理剂的非限制性实施例包括选自下列的那些物质:多元醇、聚丙二醇、聚乙二醇、尿素、吡咯烷酮羧酸、乙氧基化的和/或丙氧基化的C3-C6二醇和三醇、α-羟基C2-C6羧酸、乙氧基化的和/或丙氧基化的糖、聚丙烯酸共聚物、具有多达约12个碳原子的糖、具有多达约12个碳原子的糖醇,以及它们的混合物。有用的亲水调理剂的具体实施例包括以下物质,例如尿素,胍,乙醇酸和乙醇酸盐(例如,铵盐和烷基季铵盐),乳酸和乳酸盐(例如,铵盐和烷基季铵盐),蔗糖、果糖、葡萄糖、赤藓糖、赤藓醇、山梨醇、甘露糖醇、甘油、己三醇、丙二醇、丁二醇、己二醇等,聚乙二醇如PEG-2、PEG-3、PEG-30、PEG-50,聚丙二醇如PPG-9、PPG-12、PPG-15、PPG-17、PPG-20、PPG-26、PPG-30、PPG-34,烷氧基化葡萄糖,透明质酸,阳离子皮肤调理聚合物(例如,季铵聚合物如聚季铵聚合物),以及它们的混合物。在本发明的制品中,甘油是尤其优选的亲水调理剂。还可用的是这样的物质,例如各种形式的芦荟(例如,芦荟凝胶)、脱乙酰壳多糖和脱乙酰壳多糖衍生物如乳酸脱乙酰壳多糖酯、乳酰胺单乙醇胺、乙酰胺单乙醇胺,以及它们的混合物。还有用的是丙氧基化的甘油,参见1990年12月11日公布的Orr等人的美国专利4,976,953。
疏水调理剂
化妆品有益剂可以是一种或多种疏水调理剂。疏水调理剂的非限制性实例包括选自下列的那些:矿物油、凡士林、卵磷脂、氢化卵磷脂、羊毛脂、羊毛脂衍生物、C7-C40的支链烃、C1-C30羧酸的C1-C30醇酯、C2-C30二羧酸的C1-C30醇酯、C1-C30羧酸的甘油单酯、C1-C30羧酸的甘油二酯、C1-C30羧酸、C1-C30羧酸的乙二醇单酯、C1-C30羧酸的乙二醇二酯、C1-C30羧酸的丙二醇单酯、C1-C30羧酸的丙二醇二酯、C1-C30羧酸单酯和糖的多酯、聚二烷基硅氧烷、聚二芳基硅氧烷、聚烷芳基硅氧烷、具有3至9个硅原子的环甲基硅酮、植物油、氢化植物油、聚丙二醇的C4-C20烷基醚、二C8-C30烷基醚及其组合。
含约7至约40个碳原子的直链和支链烃可用于本发明。这些烃物质的非限制性实施例包括十二烷、异十二烷、角鲨烷、胆固醇、氢化聚异丁烯、二十二烷(即,C22烃)、十六烷、异十六烷(由Presperse,South Plainfield,NJ以Permethyl101A出售的市售烃)。C7-C40异链烷烃,是一类C7-C40支链烃,可用于本发明。聚癸烯是支链液态烃,也可用于本发明,并可以商品名Puresyn100和Puresyn 3000购自Mobile Chemical(Edison,NJ)。
还可用的是C1-C30羧酸和C2-C30二羧酸的C1-C30醇酯,其包括直链和支链的物质以及芳族衍生物。还可用的是酯,例如C1-C30羧酸的甘油单酯、C1-C30羧酸的甘油二酯、C1-C30羧酸的甘油三酯、C1-C30羧酸的乙二醇单酯、C1-C30羧酸的乙二醇二酯、C1-C30羧酸的丙二醇单酯和C1-C30羧酸的丙二醇二酯。本发明包括直链、支链和芳基羧酸。还可用的是这些物质的丙氧基化和乙氧基化的衍生物。非限制性实施例包括癸二酸二异丙酯、己二酸二异丙酯、肉豆蔻酸异丙酯、棕榈酸异丙酯、丙酸肉豆蔻酯、乙二醇二硬脂酸酯、2-乙基己基棕榈酸酯、新戊酸异癸酯、二-2-乙基己基马来酸酯、棕榈酸鲸蜡酯、肉豆蔻酸十四烷基酯、硬脂酸十八烷基酯、硬脂酸鲸蜡酯、山嵛酸山嵛基酯、马来酸二辛酯、癸二酸二辛酯、己二酸二异丙酯、辛酸鲸蜡酯、二亚油酸二异丙酯、辛酸/癸酸甘油三酯、PEG-6辛酸/癸酸甘油三酯、PEG-8辛酸/癸酸甘油三酯,以及它们的组合。
还可用的是糖和相关物质的各种C1-C30单酯和多酯。这些酯衍生自糖或多元醇部分和一种或多种羧酸部分。根据酸和糖组分,这些酯在室温下可以呈液体或固体的形式。液体酯的实施例包括:葡萄糖四油酸酯、大豆油脂肪酸(不饱和的)的葡萄糖四酯、混合的大豆油脂肪酸的甘露糖四酯、油酸的半乳糖四酯、亚油酸的阿拉伯糖四酯、木糖四亚油酸酯、半乳糖五油酸酯、山梨醇四油酸酯、不饱和大豆油脂肪酸山梨醇六酯、木糖醇五油酸酯、蔗糖四油酸酯、蔗糖五油酸酯、蔗糖六油酸酯、蔗糖七油酸酯、蔗糖八油酸酯以及它们的混合物。固体酯的实施例包括:山梨醇六酯,其中羧酸酯部分是摩尔比为1∶2的棕榈油酸酯和花生酸酯;棉子糖的八酯,其中羧酸酯部分是摩尔比为1∶3的亚油酸酯和山嵛酸酯;麦芽糖的七酯,其中酯化羧酸部分是摩尔比为3∶4的向日葵籽油脂肪酸和二十四烷酸酯;蔗糖的八酯,其中酯化羧酸部分是摩尔比为2∶6的油酸酯和山嵛酸酯;蔗糖的八酯,其中酯化羧酸部分是摩尔比为1∶3∶4的月桂酸酯、油酸酯和山嵛酸酯。优选的固体物质是蔗糖聚酯,其中酯化度为7至8,且其中脂肪酸部分是C18的一元和/或二元不饱和脂肪酸和山嵛酸,其中不饱和脂肪酸与山嵛酸的摩尔比为1∶7至3∶5。尤其优选的固体糖聚酯是蔗糖八酯,其中分子中存在约7个山嵛脂肪酸部分和约1个油酸部分。其它物质包括蔗糖的棉籽油或大豆油脂肪酸酯。这些酯物质进一步描述于1977年1月25日公布的授予Jandacek的美国专利2,831,854、美国专利4,005,196;1977年1月25日公布的授予Jandacek的美国专利4,005,195;1994年4月26日公布的授予Letton等人的美国专利5,306,516;1994年4月26日公布的授予Letton等人的美国专利5,306,515;1994年4月26日公布的授予Letton等人的美国专利5,305,514;1989年1月10日公布的授予Jandacek等人的美国专利4,797,300;1976年6月15日公布的授予Rizzi等人的美国专利3,963,699;1985年5月21日公布的授予Volpenhein的美国专利4,518,772和1985年5月21日公布的授予Volpenhein的美国专利4,517,360中。
非挥发性的硅氧烷如聚二烷基硅氧烷、聚二芳基硅氧烷和聚烷芳基硅氧烷也是可用的油。这些硅氧烷描述于在1991年12月3日公布的授予Orr的美国专利5,069,897中。聚烷基硅氧烷符合化学通式R3SiO[R2SiO]xSiR3,其中R是烷基(优选R为甲基或乙基、更优选甲基),x为达约500的整数,选择这些参数以获得所需的分子量。市售的聚烷基硅氧烷包括聚二甲基硅氧烷,也称为二甲基硅油,其非限制性实施例包括由General Electric Company出售的Vicasil系列和由Dow Corning Corporation出售的Dow Corning200系列。可用于本发明的聚二甲基硅氧烷的具体实施例包括粘度为10厘沲且沸点大于200℃的Dow Corning225流体,和粘度分别为50,350和12,500厘沲且沸点大于200℃的Dow Corning200流体。还可用的是这些物质,如三甲基甲硅烷氧基硅酸酯,它是符合化学通式[(CH2)3SiO1/2]x[SiO2]y的聚合材料,其中x是约1至约500的整数,且y是约1至约500的整数。市售的三甲基甲硅烷氧基硅酸酯是以带有聚二甲基硅氧烷的混合物且以Dow Corning593流体出售。还用于本发明的是聚二甲基硅氧烷醇,其为羟基封端的二甲基硅氧烷。这些物质可以化学通式R3SiO[R2SiO]xSiR2OH和HOR2SiO[R2SiO]xSiR2OH表示,其中R是烷基(R优选为甲基或乙基,更优选为甲基),且x是高达约500的整数,选择这些参数以获得所需的分子量。市售的聚二甲基硅氧烷醇典型地以含聚二甲基硅氧烷或环甲基聚硅氧烷的混合物(例如Dow Corning1401、1402和1403流体)出售。还用于本发明的是聚烷基芳基硅氧烷,25℃粘度为约15至约65厘沲的聚甲基苯基硅氧烷是优选的。可得到这些物质,例如SF 1075甲基苯基液体(由General Electric Company出售)和556化妆品级苯基聚三甲基硅氧烷流体(由Dow Corning Corporation出售)。烷基化硅氧烷如甲基癸基硅氧烷和甲基辛基硅氧烷可用于本发明,并且购自GeneralElectric Company。烷基改性硅氧烷也是可用的。它们包括烷基聚甲基硅氧烷和烷基聚二甲基硅氧烷,其中烷基链包含10至50个碳。这类硅氧烷以商品名ABIL WAX 9810(C24-C28烷基聚甲基硅氧烷)(由Goldschmidt出售)和SF1632(鲸蜡硬脂基聚甲基硅氧烷)(由GeneralElectric Company出售)市售。还尤其用作制剂助剂/调理剂的为环甲基硅氧烷/聚二甲基硅氧烷共聚醇混合物。适合的混合物以商品名DC 3225Q出售。
植物油和氢化植物油也可用于本文。植物油和氢化植物油的实施例包括红花油、蓖麻油、椰子油、棉籽油、鲱油、棕榈仁油、棕榈油、花生油、豆油、油菜籽油、亚麻籽油、米糠油、松油、芝麻油、向日葵籽油、氢化红花油、氢化蓖麻油、氢化椰子油、氢化棉子油、氢化鲱油、氢化棕榈仁油、氢化棕榈油、氢化花生油、氢化豆油、氢化油菜籽油、氢化亚麻籽油、氢化米糠油、氢化芝麻油、氢化向日葵籽油,以及它们的混合物。
还可用的是聚丙二醇的C4-C20烷基醚、聚丙二醇的C1-C20羧酸酯,以及二C8-C30烷基醚。这些物质的非限制性实施例包括PPG-14丁基醚、PPG-15硬脂基醚、二辛基醚、十二烷基辛基醚,以及它们的混合物。
疏水性螯合剂作为疏水调理剂也用于本发明。适合的试剂描述于1983年6月7日公布的授予Scanlon等人的美国专利4,387,244和以Schwartz等人的名义于1999年2月26日提交的共同未决的美国专利申请序列号09/258,747和09/259,485中。
优选的疏水调理剂选自矿物油、凡士林、卵磷脂、氢化卵磷脂、羊毛脂、羊毛脂衍生物、C7-C40支链烃、C1-C30羧酸的C1-C30醇酯、C2-C30二羧酸的C1-C30醇酯、C1-C30羧酸的甘油单酯、C1-C30羧酸的甘油二酯、C1-C30羧酸的甘油三酯、C1-C30羧酸的乙二醇单酯、C1-C30羧酸的乙二醇二酯、C1-C30羧酸的丙二醇单酯、C1-C30羧酸的丙二醇二酯、糖的C1-C30羧酸单酯和聚酯、聚二烷基硅氧烷、聚二芳基硅氧烷、聚烷基芳基硅氧烷、具有3至9个硅原子的环二甲基硅氧烷、植物油、氢化植物油、聚丙二醇C4-C20烷基醚、二C8-C30烷基醚,以及它们的组合。
散光剂
受权利要求书保护的套盒的组合物可包含散光剂作为化妆品有益剂。散光剂可用于通过减少纹理如孔和细纹的出现来改善皮肤外观。包含在本套盒组合物中适合的散光剂包括,但不限于,二氧化硅、尼龙、聚乙烯、聚甲基甲基丙烯酸酯、聚苯乙烯、甲基硅氧烷共聚物、聚四氟乙烯共聚物、氮化硼、硅氧烷树脂粉末、硅氧烷橡胶粉末、乙烯丙烯酸酯共聚物、云母、二氧化钛、氧化锌,以及它们的组合。
脱屑剂
本发明的组合物可包括一种或多种脱屑剂。这种脱屑剂可用于改善皮肤的更替,从而使皮肤看起来恢复了活力且显得更年轻。例如,脱屑活性物质趋于改善皮肤肌理(例如,光滑性)。适用于本文的一个脱屑体系包含巯基化合物和两性离子表面活性剂,其描述在授予Bissett的美国专利5,681,852中。另一个适用于本文的脱屑体系包含水杨酸和两性离子表面活性剂,其描述在授予Bisset的美国专利5,652,228中。两性离子表面活性试剂,如描述在这些申请中的,也可用作本文脱屑剂,而鲸蜡基甜菜碱是尤其优选的。
亮肤剂
其它适合的化妆品有益剂是亮肤剂。适合的亮肤剂包括本领域已知的那些物质,包括曲酸、熊果苷、去氧熊果苷、抗坏血酸及其衍生物,例如抗坏血酸磷酸镁或抗坏血酸磷酸钠或其它抗坏血酸磷酸盐。
皮肤抚慰和皮肤愈合活性物质
安全有效量的皮肤抚慰或皮肤愈合活性物质可以加入到本组合物中,按形成的组合物的重量计,优选约0.1%至约30%、更优选约0.5%至约20%、还更优选约0.5%至约10%。可用于本文的皮肤抚慰或皮肤愈合活性物质包括泛酸衍生物(包括泛醇、右旋泛醇、乙基泛醇)、芦荟、尿囊素、红没药醇和甘草酸二钾盐。
防晒活性物质
还可用作本文的化妆品有益剂是防晒活性物质。各种各样的防晒活性物质描述于1992年2月11日公布的授予Haffey等人的美国专利5,087,445、1991年12月17日公布的授予Turner等人的美国专利5,073,372、1991年12月17日公布的授予Turner等人的美国专利5,073,371、和Sagarin等人的“Cosmetics Science andTechnology”,第VIII章,第189页及以下。用于本发明组合物的防晒剂的非限制性实施例选自对甲氧基肉桂酸2-乙基己基酯、N,N-二甲基对氨基苯甲酸2-乙基己基酯、对氨基苯甲酸、2-苯基苯并咪唑-5-磺酸、氰双苯丙烯酸辛酯、羟甲氧二苯酮、水杨酸高薄荷酯、水杨酸辛酯、4,4′-甲氧基-叔丁基二苯甲酰基甲烷、4-异丙基二苯甲酰基甲烷、3-亚苄基樟脑、3-(4-甲基亚苄基)樟脑、二氧化钛、二氧化硅、氧化铁,以及它们的混合物。其它可用的防晒剂还有那些公开于1990年6月26日公布的授予Sabatelli的美国专利4,937,370、和1991年3月12日公布的授予Sabatelli等人的美国专利4,999,186中的物质。这些防晒剂的尤其优选的实施例包括选自以下物质的那些:2,4-二羟基二苯甲酮的4-N,N-(2-乙基己基)甲氨基苯甲酸酯、含4-羟基二苯甲酰基甲烷的4-N,N-(2-乙基己基)甲氨基苯甲酸酯、2-羟基-4-(2-羟基乙氧基)二苯酮的4-N,N-(2-乙基己基)甲氨基苯甲酸酯、4-(2-羟基乙氧基)二苯甲酰甲烷的4-N,N-(2-乙基己基)甲氨基苯甲酸酯、以及它们的混合物。可使用的防晒剂的准确用量应取决于所选的防晒剂和要达到的所需防晒因子(SPF)。SPF是防晒剂的抗红斑光保护作用的常用量度。
维生素化合物
本组合物可包含维生素化合物、其前体及衍生物作为化妆品有益剂。这些维生素化合物可以是天然的或合成的形式。适合的维生素化合物包括,但不限于,维生素A(如,β胡萝卜素、视黄酸、视黄醇、类视黄醇、棕榈酸视黄酯、丙酸视黄酯等)、维生素B(如,烟酸、烟酰胺、核黄素、泛酸等)、维生素C(如,抗坏血酸等)、维生素D(如麦角固醇、麦角钙化醇、胆钙化醇等)、和维生素E(如,生育酚)。
酶
本发明的化妆品有益剂可以是一种或多种酶。优选地,这些酶是皮肤病学可接受的。适合的酶包括,但不限于,角蛋白酶、蛋白酶、淀粉酶、枯草杆菌蛋白酶、其它肽和蛋白质等。
肽可作为化妆品有益剂以安全有效的量包括于本发明,肽包括但不限于二肽、三肽、四肽和五肽及其衍生物。本文所用的“肽”是指天然存在的肽和合成肽。还可用于本文的是天然存在的和市售的含肽组合物。
螯合剂
本套盒组合物中的化妆品有益剂可以是螯合剂。本文所用的“螯合剂”或“螯合试剂”是指能通过形成络合物从体系中移除金属离子的试剂,这样金属离子不能容易地参加或催化化学反应。螯合剂的加入尤其适用于提供保护,以防止可引起脱皮加重或皮肤肌理改变的紫外线辐射,以及防止可引起皮肤损伤的其它环境剂。
适用于本发明的示例性螯合剂公开于1996年1月30日公布的授予Bissett等人的美国专利5,487,884、1995年10月31日公布的Bush等人的国际公开91/16035和1995年10月31日公布的Bush等人的国际公开91/16034中。用于本发明组合物的优选螯合剂是糠偶酰二肟、糠偶酰二肟衍生物、糠偶酰一肟、糠偶酰一肟衍生物,以及它们的组合。
类黄酮
本发明的化妆品有益剂也可以是类黄酮。类黄酮广泛地公开于美国专利5,686,082和5,686,367中。
甾醇
本发明的化妆品有益剂也可以是安全有效量的一种或多种甾醇化合物。可使用的甾醇化合物的实施例包括谷甾醇、豆甾醇、菜油甾醇、芸苔甾醇、羊毛甾醇、7-脱氢胆甾醇,以及它们的混合物。它们可以是合成的或来自天然源的,例如从植物萃取的混合物(例如,植物甾醇)。
第二组合物
本发明套盒组合物的第二组合物包含安全有效量的一种或多种折射指数大于约2.0的着色剂和美容可接受载体。这种第二组合物的主要用途是递送通过使用面部粉底使用者试图得到的所需遮盖或颜色,以及通过覆盖或掩盖色调缺陷来均匀皮肤色调。然而,这种第二组合物也可有助于提供附加化妆品有益剂在皮肤表面的沉积和亲和性。例如,在某些实施方案,第二组合物可包含与第一组合物中存在的相同或类似的化妆品有益剂,这样,由于这种多步方法,递送并随后沉积在皮肤上的量增加。具体地讲,为了获得持久的产品,如一起协同作用的其它化妆品有益剂可同时掺入第一和第二组合物中一样,成膜剂可被同时掺入第一和第二组合物中,以提供改善的有益效果。
第二组合物的着色剂显示具有的折射指数大于约2.0。申请者发现具有较高折射指数的着色剂尤其可用于第二组合物中,因为所述第二组合物的主要功能是赋予底层皮肤颜色和色调覆盖。关于可用于本发明第二组合物中的着色剂,各种各样的着色剂适用于本文。例如,适合的着色剂包括但不限于:D&C黄7号、D&C红36号、FD&C红4号、D&C橙4号、D&C红6号、D&C红34号、FD&C黄6号、D&C红33号、FD&C黄5号、D&C棕1号、D&C红17号、FD&C绿3号、D&C蓝4号、D&C黄8号、D&C橙5号、D&C红22号、D&C红21号、D&C红28号、D&C橙11号、D&C黄10号、Ext.D&C紫2号、D&C紫2号、D&C绿6号、D&C绿5号、D&C红30号、D&C绿8号、D&C红7号、FD&C蓝1号、D&C黄7号、D&C红27号、D&C橙10号、D&C红31号、FD&C红40号、D&C黄11号、胭脂树提取物、β胡萝卜素、鸟嘌呤、胭脂红、铝粉、群青颜料、氯氧化铋、氧化铬绿、氢氧化铬绿、氧化铁、亚铁氰化铁、锰紫、二氧化钛、钛酸盐云母(即,涂敷二氧化钛的云母)、氧化铁钛酸云母、氧化锌、焦糖染色、云母、氰亚铁酸铵铁、二羟基丙酮、愈创烯、叶蜡石、青铜粉、铜粉、硬脂酸铝、硬脂酸钙、核黄素、硬脂酸镁、硬脂酸锌、辣椒红/辣椒玉红素、膨润土、硫酸钡、碳酸钙、硫酸钙、碳黑、碳酸镁、硅酸镁、有色二氧化硅、二氧化硅(包括球形二氧化硅、水合二氧化硅和二氧化硅小球)、CI 10020、CI 11680、CI 15630、CI 15865、CI 16185、CI 16255、CI 16255、CI 45430、CI 69825、CI 73000、CI73015、CI 74160、CI 75100、CI 77002、CI 77346、CI 77480、尼龙粉末、聚乙烯粉末、乙烯丙烯酸酯共聚物粉末、甲基丙烯酸酯粉末、聚苯乙烯粉末、丝绸粉末、结晶纤维素、淀粉、氯氧化铋、鸟嘌呤、高岭土、白垩、硅藻土、微海绵、氮化硼等。另外,也可使用这些着色剂的色淀或组合物。可用于本发明的附加着色剂、颜料和粉末描述于1996年4月9日授予Castrogiovanni等人的美国专利5,505,937中。
在本发明的优选实施方案中,第二组合物包含按组合物的重量计约0.5%至约80.0%的高折射率着色剂。实际上,第二组合物中甚至更优选的着色剂用量(按优选性增加的顺序)按组合物的重量计为约0.5%至约50.0%、0.5%至约40.0%、1.0%至约35.0%、和1.5%至约30.0%。
美容可接受载体
本发明的第一和第二组合物分别包含第一化妆品有益剂和颜料的美容可接受载体。适合的载体在本领域中是熟知的,并且基于最终的应用而进行选择。例如,本发明的载体包括但不限于那些适于涂敷于皮肤上的载体。优选地,本发明的载体适于涂敷于皮肤上(例如,防晒剂、霜膏、乳剂、露剂、面膜、浆液等)。这些载体对于本领域的普通技术人员而言是熟知的,并且可包含一种或多种适于涂敷于皮肤上的相容液体或固体填充稀释剂或赋形剂。载体的准确用量应取决于第一组合物中第一化妆品有益剂的含量和第二组合物中颜料的含量,以及包含在每个组合物中的任何任选成分,本领域普通技术人员将该任选成分列为与载体完全不同(如,其它活性组分)。每个本发明的第一和第二组合物优选包含按组合物的重量计约5%至约99%,更优选约10%至约98%,最优选约10%至约97%的载体。
本文载体和组合物可以多种方式配制,所述方式包括但不限于乳液。例如,适合的乳液包括水包油、油包水、硅氧烷包水、水包硅氧烷、水包油包水、油包水包油和硅氧烷包水包油乳液。优选的第一组合物包含水包油乳液,而优选的第二组合物包含硅氧烷包水乳液。
本发明的组合物可配制成各种各样的产品类型,包括粉末、霜膏、蜡、糊剂、露剂、乳剂、摩丝、凝胶、油、滋补剂和喷雾剂。优选的组合物被配制成有色化妆品产品,甚至更优选面部粉底,甚至更优选液体、露剂、霜膏、凝胶、喷雾剂以及它们的组合形式的面部粉底。在某些实施方案中,任何一种本套盒组合物可静电涂敷于皮肤,如描述于共同未决的申请序列号09/628,631、09/629734、09/629765、09/628630中,所有均提交于2000年7月31日,并权利要求的优先权至2000年5月31日。配制这种产品所需的任何附加组分随产品类型不同而改变并且可由本领域的技术人员常规选择。
任选成分
本发明的组合物可包含各种其它成分,如常规用于给定产品类型中的那些成分,前提条件是它们不会不可接受地改变本发明的有益效果。这些任选组分应适合应用于哺乳动物的皮肤,即当将其掺入到组合物中时,在合理的医学或配制人员的判断范围内,它们适于与人的皮肤接触,而不会有过度的毒性、不相容性、不稳定性、变应性反应等。“CTFA Cosmetic Ingredient Handbook”第二版(1992)描述了各种各样的通常用于皮肤护理领域的、适用于本发明组合物的非限制性化妆品和药物成分。适合的任选成分包括:
油溶的聚合胶凝剂
本发明的组合物可任选包括一种或多种聚合材料,该聚合材料为油溶的,并且与包含在组合物中的疏水性物质(例如,油)形成凝胶。这种聚合物有益于构建这些材料,以得到具有改善的稳定性和抗剪切的柔韧性凝胶。
尤其适合的是软化点小于160℃的至少部分交联的油溶聚合材料。适合的物质来自于下列物质的化学基团:PE(聚乙烯)、PVA(聚乙烯醇)及衍生物、PVP(聚乙烯吡咯烷酮)及衍生物、PVP/烯烃共聚物、PVP/VA共聚物、PVM/MA(甲基乙烯基醚/马来酸酐)共聚物和它们的酯和醚,尤其是聚(烷基乙烯醚-共-马来酸酐)共聚物、乙烯/VA共聚物、丙烯酸酯/烷基甲基丙烯酸酯、苯乙烯/异戊二烯、苯乙烯/乙烯/丁烯、苯乙烯/乙烯/丙烯、苯乙烯/乙烯/丁烯/苯乙烯、苯乙烯/丁二烯共聚物、膨润土粘土,锂蒙脱石粘土、有机蜡和硅氧烷蜡。适合的物质可购自,例如,Dupont(ELVAX型)、BASF(LUVISKOL型)、Shell(KRATON聚合物)、ISP(PVP、GANTREZ、GANEX和ALLIAN2OPT型)和Rohm & Haas(LIPACRYL)。
亲水胶凝剂
本发明的组合物可任选包含亲水胶凝剂的含量优选为约0.01%至约10%,更优选约0.02%至约2%,尤其约0.02%至约0.5%。该胶凝剂优选具有的粘度(1%水溶液,20℃,Brookfield RVT)至少为约4000mPa·s,更优选至少约10,000mPa·s,并且尤其至少约50,000mPa·s。
适合的亲水胶凝剂通常可描述为水溶性或胶状水溶性聚合物,并且包括纤维素醚(如羟乙基纤维素、甲基纤维素、羟丙基甲基纤维素)、膨润土粘土、锂蒙脱石粘土、聚乙烯吡咯烷酮、聚乙烯醇、聚季胺盐-10、瓜尔胶、羟丙基瓜尔胶和黄原胶。
其中适合的亲水性凝胶剂是丙烯酸/丙烯酸乙酯共聚物和由B.F.Goodrich Company以商标Carbopol树脂出售的羧基乙烯基聚合物。这些树脂基本上是由胶态水溶性的聚烯烃聚醚交联聚合物组成,所述聚合物是由丙烯酸与0.75%至2.00%的交联剂如聚烯丙基蔗糖或聚烯丙基季戊四醇交联而得到。其实施例包括Carbopol 934、Carbopol 940、Carbopol 950、Carbopol 980、Carbopol 951和Carbopol 981。Carbopol 934是丙烯酸与约1%的蔗糖聚烯丙基醚交联形成的水溶性聚合物,其中每个蔗糖分子平均具有约5.8个烯丙基。还适用于本发明的是具有两性分子特性的丙烯酸的疏水改性的交联聚合物,其商品名为Carbopol 1382、Carbopol 1342和PemulenTR-1(CTFA名称:丙烯酸酯/10-30烷基丙烯酸酯交联聚合物)。聚烯基聚醚交联的丙烯酸聚合物和疏水改性交联的丙烯酸聚合物的组合物也适用于本发明。其它适用于本发明的适合的胶凝剂是油凝胶,例如三羟基硬脂精和羟基硬脂酸铝镁。本发明的胶凝剂在常温和高温下对于提供极好的稳定性来说是尤其有价值的。
适用于中和酸性基团且包含中和本发明亲水胶凝剂的中和剂包括氢氧化钠、氢氧化钾、氢氧化铵、单乙醇胺、二乙醇胺和三乙醇胺。
乳化剂/表面活性剂
乳化剂(也称为“表面活性剂”)也可包含在本发明的组合物中,尤其当组合物包含乳液时。
各种各样的乳化剂可用于本发明,并且包括选自阴离子乳化剂、非离子乳化剂、阳离子乳化剂、两性乳化剂以及它们组合的那些。
优选的乳化剂选自阴离子乳化剂,其选自月桂酰肌氨酸铵、三癸基醚硫酸钠、月桂酰肌氨酸钠、月桂基聚氧乙烯醚硫酸铵、月桂基聚氧乙烯醚硫酸钠、十二烷基硫酸铵、月桂基硫酸钠、椰油基羟乙基磺酸铵、椰油基羟乙基磺酸钠、月桂酰羟乙基磺酸钠、鲸蜡基硫酸钠、一月桂基磷酸钠、乙氧基化一烷基磷酸盐、椰油甘油基醚磺酸钠、C9-C22皂钠以及它们的组合;非离子乳化剂,其选自月桂胺氧化物、椰油胺氧化物、癸基多聚葡萄糖、月桂基多聚葡萄糖、蔗糖椰油酸酯、C12-14葡糖酰胺、月桂酸蔗糖酯以及它们的组合;阳离子乳化剂,其选自脂肪胺、二脂肪季铵、三脂肪季铵、咪唑啉季铵以及它们的组合;两性乳化剂,其选自月桂酰两性二乙酸二钠、月硅酰两性乙酸钠、鲸蜡基二甲基甜菜碱、椰油酰胺基丙基甜菜碱、椰油酰胺基丙基羟基磺基甜菜碱以及它们的组合。
交联硅氧烷聚合物
本发明的组合物可任选包含性质上为非直链的聚合物。包含在受权利要求书保护的组合物中适合的聚合物包括但不限于为交联有机聚硅氧烷聚合物凝胶网络的聚硅氧烷。例如,尤其适合的交联有机聚硅氧烷聚合物凝胶网络是由环氧官能化的有机聚硅氧烷在酸催化剂的存在下通过聚合反应形成的。有机聚硅氧烷聚合物为选自非乳化聚合物凝胶网络、乳化聚合物凝胶网络以及它们的组合的交联有机聚硅氧烷聚合物凝胶网络。该物质的具体实施例描述于美国专利6,531,540B1、美国专利6,538,061 B2、美国专利6,444,745 B1、美国专利6,346,583 B1、美国专利5,654,362,US Patent 5,811,487、美国专利5,880,210、美国专利5,889,108、美国专利5,929,164、美国专利5,948,855、美国专利5,969,035、美国专利5,977,280、美国专利6,080,394、美国专利6,168,782、美国专利6,177,071、美国专利6,200,581、美国专利6,207,717、美国专利6,221,927、美国专利6,221,979、美国专利6,238,657和美国专利4,987,169中。
适合的有机聚硅氧烷聚合物网络粉末包括乙烯基聚二甲基硅氧烷/聚甲基硅氧烷倍半硅氧烷交联聚合物如Shin-Etsu的KSP-100、KSP-101、KSP-102、KSP-103、KSP-104、KSP-105,包含氟代烷基基团的混合硅氧烷粉末如Shin-Etsu的KSP-200,以及包含苯基基团的混合硅氧烷粉末例如Shin-Etsu的KSP-300;和Dow Corning的DC9506。
优选的有机聚硅氧烷组合物为聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物。这些聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物由许多供货商提供,包括Dow Corning(DC 9040和DC9041)、General Electric(Velvesil 125)、General Electric(SFE 839)、Shin Etsu(KSG-15、16、18[聚二甲基硅氧烷/苯基乙烯基聚二甲基硅氧烷交联聚合物]和KSG-21[聚二甲基硅氧烷共聚多元醇交联聚合物])、Grant Industries(GransilTM系列物质)、由Shin Etsu提供的月桂基聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物(如,KSG-41、KSG-42、KSG-43和KSG-44)、也由Shin-Etsu提供的月桂基聚二甲基硅氧烷/聚二甲基硅氧烷共聚多元醇交联聚合物(如,KSG-31、KSG-32、KSG-33和KSG-34)、和Wacker(Belsil RG-100)。适用于本发明的其它来自于Shin-Etsu的聚合物包括KSG-210、-310、320、330和340。可用于本发明的交联有机聚硅氧烷聚合物凝胶网络和制备它们的方法进一步描述于1990年11月13日公布的授予Sakuta等人的美国专利4,970,252、1998年6月2日公布的授予Kilgour等人的美国专利5,760,116、1997年8月5日公布的授予Schulz,Jr.等人的美国专利5,654,362,和转让给Pola Kasei Kogyo KK.的日本专利申请JP 61-18708中。
相关方法
申请者发现本发明的化妆品套盒尤其可用作多步面部粉底产品。然而,期望技术人员能够想到与所公开的使用方法相匹配的公开于本发明的那些适当的化妆品有益剂。本发明公开的和受权利要求书保护的化妆品套盒的使用方法包括但不限于:1)增加化妆品活性物质对皮肤亲和性的方法;2)保湿皮肤的方法;3)改善皮肤自然外观的方法;4)有色化妆品涂敷于皮肤上的方法;5)为皮肤提供止汗功效的方法;6)预防、延迟、和/或治疗皱纹的方法;7)为皮肤提供紫外线保护的方法;8)预防、延迟、和/或治疗出油的方法;9)调整皮肤感觉和纹理的方法;10)提供均匀皮肤色调的方法;11)预防、延迟、和/或治疗出现蛛形血管和静脉曲张的方法;12)遮盖皮肤上出现毫毛的方法;13)隐蔽人类皮肤上的瑕疵和/或缺陷的方法,包括痤疮、老年斑、雀斑、黑痣、疤痕、眼袋、胎记、发炎后色素沉着过度等;和14)预防、延迟、和/或治疗哺乳动物恶臭的方法。本文所述的每个方法涉及顺序将第一和第二组合物局部涂敷于皮肤上。然而,每个受权利要求书保护的方法可涉及附加步骤,该步骤重点在于使用包含其它化妆品有益剂的附加组合物。
实施例
下列实施例进一步描述和举例说明了本发明范围内的具体实施方案。在下列实施例中,所有成分均以活性物质的含量列出。所给的这些实施例仅仅是说明性的,而不可理解为是对本发明的限制,因为在不背离本发明精神和范围的条件下可以进行多种改变。
第一组合物的实施例
实施例1至5
包含收敛剂、光泽控制吸收剂、防红/黄珍珠颜料、维生素和防晒活性物质的水包油第一组合物。
成分 实施例1 实施例2 实施例3 实施例4 实施例5
A相:
水 适量 适量 适量 适量 适量
甘油 5.00 5.00 5.00 5.00 5.00
乙二胺四乙酸二钠 0.10 0.10 0.10 0.10 0.10
对羟基苯甲酸甲酯 0.25 0.25 0.25 0.25 0.25
B相:
甲氧基肉桂酸辛酯 - - - 6.00 -
氰双苯丙烯酸辛酯 - - - - 1.50
阿优苯宗 - - - - 2.50
水杨酸辛酯 - - - - 4.00
苯基苯并咪唑
磺酸 - - - - 1.00
异十六烷 3.00 3.00 3.00 2.00 -
异硬脂酸异丙酯 2.00 10.00 10.00 2.00 2.00
鲸蜡醇 1.00 1.00 1.00 1.00 1.00
硬脂酸 0.20 0.20 0.20 0.20 0.20
PEG-100硬脂酸酯 0.10 0.10 0.10 0.10 0.10
十六硬酯酸葡糖苷 0.20 0.20 0.20 0.20 0.20
氧化锌 - - - 4.50 -
对羟基苯甲酸乙酯 0.15 0.15 0.15 0.15 0.15
对羟基苯甲酸丙酯 0.10 0.10 0.10 0.10 0.10
C相:
二氧化钛
尼龙-12 3.00 2.00 2.00 2.00 2.00
聚氨酯球1 2.00 2.00 2.00 2.00 2.00
吸收剂颗粒2 1.00 4.00 2.00 2.00
云母和二
氧化钛3 3.00 - - - -
水合氯化铝 - - 5.00 - -
D相:
聚丙烯酰胺4 1.25 1.25 3.00 2.00 2.00
E相:
氢氧化钠 0.03 0.03 0.03 0.03 0.03
F相:
烟酰胺 - - - 3.5 3.5
D-泛醇 - - - 0.5 0.5
乙酸生育酚酯 - - - 0.5 0.5
G相:
苄基醇 0.25 0.25 0.25 0.50 0.50
药用拟层孔菌
提取物5 5.00 3.00 3.00 - -
聚二甲基硅氧烷和
聚二甲基硅氧烷醇 2.00 3.00 3.00 2.00 2.00
H相:
丙烯酸酯/C12-22
烷基甲基丙烯酸酯
共聚物6 - 2.50 2.50 - -
1聚氨酯球以商品名BPD500T购自Kobo Products
2吸收皮脂和汗液的颗粒包括,但不限于,购自Kobo Products的Silica Shells或MSS-500/3H4形式的二氧化硅,购自BeautySolutions的Polypore E200或L200形式的烯丙基甲基丙烯酸酯交联聚合物,购自Miyoshi Kasei的Sebumase形式的硅酸铝镁、或吸收淀粉如购自National Starch的Natrasorb Bath或NatrasorbHFB。
3云母和二氧化钛珍珠颜料包括,但不限于,购自Rona的防红用Timiron Silk Green或Timiron Super Green或防黄用TimironSilk Blue或Timiron Super Blue。
4含C13-C14异链烷烃的聚丙烯酰胺和月桂基聚氧乙烯醚-7以商品名Sepigel 305购自Seppic。
5分散于1,3-丁二醇中的收敛性药用拟层孔菌提取物以商品名LS8865购自Laboratoires Serobiologique。
6丙烯酸酯/C12-22烷基甲基丙烯酸酯共聚物以商品名Allianz OPT购自International Specialty Products。
混合A相成分,然后加热至75℃。混合B相成分,然后加热至75℃。A和B相都应使用低剪切螺旋或涡轮搅拌器搅拌以确保相均匀。一旦A和B相都达到75℃,将这两相混合并用高剪切搅拌器以8000rpm至10000rpm乳化10分钟。将C相成分加入乳液中,然后用螺旋或涡轮搅拌器搅拌5分钟至10分钟,确保产生良好的涡旋以分散固体并打碎大的附聚物。如果必要的话,将C相混入A/B相中的步骤可使用高剪切搅拌器以5000rpm至10000rpm搅拌和使用带侧壁刮板的锚定型搅拌器作为补充。一旦固体被分散后,开始冷却乳液,同时用螺旋或涡轮搅拌器和侧刮板搅拌。一旦乳液温度达到60℃,加入D相聚丙烯酰胺增稠剂,然后用螺旋或涡轮搅拌器搅拌5至10分钟,确保产生良好的涡旋以分散该聚合物。乳液冷却至55℃然后加入E相。冷却至50℃然后加入F和G相。继续用螺旋或涡轮搅拌器搅拌,同时乳液冷却至35℃至40℃。一旦乳液达到35℃至40℃,可将产品转移至合适的贮存容器中。
实施例6至8
硅氧烷包水第一组合物
成分 实施例6 实施例7 实施例8
A相:
水 20.00 20 20.00
甘油 10.00 10.00 -
乙二胺四乙酸二钠 0.10 0.10 0.10
药用拟层孔菌提取物 5.00 5.00 5.00
对羟基苯甲酸甲酯 0.25 0.25 0.25
乙醇 - - 10.00
苄基醇 0.25 0.25 0.25
B相:
环戊硅氧烷 适量 适量 适量
丙烯酸酯/聚二甲基硅氧烷共聚物1 5.00 5.00 5.00
环甲基聚硅氧烷和
聚二甲基硅氧烷交联聚合物2 25.00 20.00 42.00
聚二甲基硅氧烷共聚多元醇交联聚合物3 0.50 0.50 -
环戊硅氧烷和聚二甲基硅氧烷共聚多元醇4 9.50 9.50 -
对羟基苯甲酸乙酯 0.15 0.15 0.15
对羟基苯甲酸丙酯 0.10 0.10 0.15
水合氯化铝 - 10.00 -
硅氧烷乙二醇共聚物 - - 2.50
聚氧乙烯月桂基醚 - 0.50
聚二甲基硅氧烷5 10.00
C相:
聚甲基倍半硅氧烷 3.00 3.00 3.00
吸收剂颗粒6 4.00 4.00 4.00
1,丙烯酸酯/聚二甲基硅氧烷共聚物,如购自Shin Etsu的KP545。
2环甲基聚硅氧烷和聚二甲基硅氧烷交联聚合物,例如,但不限于,购自Dow Corning的DC9040硅氧烷弹性体混合物。
3聚二甲基硅氧烷共聚多元醇交联聚合物,如购自Shin Etsu的KSG-21、KSG-210或KSP-104自乳化弹性体。
4聚二甲基硅氧烷,例如,但不限于,购自Dow Corning的DC2001cst或DC2-1184。
5环戊硅氧烷和聚二甲基硅氧烷共聚多元醇,为DC5225C制剂助剂的形式。
6吸收皮脂和汗液的颗粒包括,但不限于,购自Kobo Products的Silica Shells、Sllica Shells-SH或MSS-500/3H4形式的二氧化硅,购自Amcol Beauty Solutions的Polypore E200或L200形式的烯丙基甲基丙烯酸酯交联聚合物,或购自Miyoshi Kasei的Sebumase形式的硅酸铝镁。
混合A相,然后用螺旋或涡轮搅拌器搅拌直至均一化。混合B相成分,然后用高剪切搅拌器以5000rpm至10000rpm搅拌直至均一化。将A相与B相混合,然后用高剪切搅拌器以5000rpm至10000rpm乳化10至20分钟。不要使乳液的温度增至40℃以上。将C相加入乳液中,然后用螺旋或涡轮搅拌器搅拌直至均一化。如果需要打碎颗粒附聚物,也可使用高剪切搅拌器。一旦颗粒完全分散,在转移至合适的容器之前使乳液冷却至室温。
实施例9
压缩粉末的第一组合物。
成分 实施例9
A相:
滑石 适量
云母 18.00
绢云母 29.00
二氧化 12.00
尼龙-12 2.00
无水硅酸 2.70
对羟基苯甲酸丙酯 0.10
对羟基苯甲酸甲酯 0.30
脱氢乙酸钠 0.10
吸收剂颗粒1 5.00
水合氯化铝 5.00
B相:
聚二甲基硅氧烷和三甲基甲硅氧烷基硅酸盐 6.5
琥珀酸二辛酯 0.80
羟基硬脂酸辛酯 1.00
乙酸生育酚酯 0.006
甲氧基肉桂酸辛酯 3.00
1吸收皮脂和汗液的颗粒包括,但不限于,购自Kobo Products的Silica Shells、Silica Shells-SH或MSS-500/3H4形式的二氧化硅,购自Amcol Beauty Solutions的Polypore E200或L200形式的烯丙基甲基丙烯酸酯交联聚合物,购自Miyoshi Kasei的Sebumase形式的硅酸铝镁,或吸收淀粉,如购自National Starch的Natrasorb Bath或Natrasorb HFB。
用整体混合将A相成分混合(如Ribbon混合器,双锥混合器或用手),然后用高剪切混合(如锤磨机、粉磨机或切碎刀片)分解任何颗粒附聚物。用螺旋混合器混合B相成分,然后加热至75℃。将B相成分加入A相中,然后组合使用整体和高剪切混合进行分散。
实施例10
适用作第一组合物的固体乳液
成分 实施例10
A相:
环甲基聚硅氧烷 适量
十三烷基异壬酸酯 2.00
乙酸生育酚酯 18.00
环戊硅氧烷和聚二甲基硅氧烷共聚多元醇 29.00
异硬脂酸脱水山梨糖醇酯 2.00
B相:
水 20.00
药用拟层孔菌提取物 5.00
1,3-丁二醇 2.00
乙二胺四乙酸二钠 0.10
对羟基苯甲酸甲酯 0.20
C相:
吸收剂颗粒 5.00
云母和二氧化钛 3.00
水合氯化铝 5.00
D相:
地蜡 2.00
对羟基苯甲酸丙酯 0.25
小烛树蜡 2.00
1吸收皮脂和汗液的颗粒包括,但不限于,购自Kobo Products的Silica Shells、Silica Shells-SH或MSS-500/3H4形式的二氧化硅,购自Amcol Beauty Solutions的Polypore E200或L200形式的烯丙基甲基丙烯酸酯交联聚合物,购自Miyoshi Kasei的Sebumase形式的硅酸铝镁,或吸收淀粉,如购自National Starch的Natrasorb Bath或Natrasorb HFB。
混合A相成分,然后在20℃至30℃下用低剪切螺旋或涡轮搅拌器搅拌直至均一化。混合B相成分,然后在20℃至30℃下用螺旋或涡轮搅拌器搅拌直至均一化。用高剪切搅拌器以5000rpm至10000rpm将A相与B相成分混合。将C相成分加入该乳液中,然后用低剪切搅拌直至分散。将D相成分加入该乳液中,然后加热至85℃。在85℃下,以5000rpm至10000rpm搅拌10分钟以确保所有蜡和固体被分散。将乳液冷却至65℃,准备倒入合适的贮存容器中。
第二组合物的实施例
实施例11至14
硅氧烷包水的第二组合物
成分 | 实施例11 | 实施例12 | 实施例13 | 实施例14 |
A相 | ||||
环戊硅氧烷和聚二甲基硅氧烷共聚醇 | 8.000 | 8.000 | 8.000 | 5.600 |
硅氧烷改性的丙烯酸树脂1 | 14.820 | 7.700 | 14.809 | 5.390 |
聚丙烯酸酯-g-聚硅氧烷树脂2 | - | 20.391 | - | 14.274 |
十三烷基新戊酸酯3 | 6.000 | 6.000 | 6.000 | 4.200 |
鲸蜡基聚二甲硅氧烷共聚多元醇4 | 2.000 | 2.000 | 2.000 | 1.400 |
环六硅氧烷 | 2.000 | - | 2.000 | - |
环戊硅氧烷 | 3.275 | 11.031 | 5.786 | 7.797 |
B相 | ||||
乙氧基化C10-16醇5 | 0.500 | 0.500 | 0.500 | 0.500 |
对羟基苯甲酸丙酯 | 0.150 | 0.150 | 0.150 | 0.150 |
C相 | ||||
黄色颜料 | 0.737 | 0.737 | 0.737 | 0.595 |
红色颜料 | 0.238 | 0.238 | 0.238 | 0.195 |
黑色颜料 | 0.130 | 0.130 | 0.130 | 0.106 |
微粉化二氧化钛 | 0.250 | 0.250 | 0.250 | 0.175 |
氮化硼处理淀粉6 | 3.500 | 3.500 | 3.500 | 2.450 |
二氧化钛 | 8.250 | 8.250 | 8.250 | 5.775 |
聚甲基倍半硅氧烷7 | 1.500 | 1.500 | 1.500 | 1.050 |
环己烷二异氰酸酯/聚丙烯/聚己酸内酯交联聚合物(和)二氧化硅8 | 1.500 | 1.500 | 1.500 | 1.050 |
聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物9 | 2.000 | 1.500 | 3.000 | 1.050 |
混合环甲基聚硅氧烷和环氧凝胶10 | - | - | - | 30.000 |
D相 | ||||
去离子水 | 40.000 | 22.973 | 35.000 | 15.583 |
SILICA SHELLS11 | 2.500 | 1.000 | 4.000 | 0.700 |
苯氧基乙醇 | 0.250 | 0.250 | 0.250 | 0.250 |
乙二胺四乙酸三钠盐 | 0.100 | 0.100 | 0.100 | 0.100 |
氯化钠 | 2.000 | 2.000 | 2.000 | 1.400 |
脱氢乙酸钠一水合物 | 0.300 | 0.300 | 0.300 | 0.210 |
总计 | 100.000 | 100.000 | 100.000 | 100.000 |
1.Shin-EtSu-KP-545
2.3M-SA-70
3.ISP-Ceraphyl 55
4.DeGussa Goldsmith-Abil WE-09
5.Rhodia-Rhodasurf L-7/90
6.National Starch-Dry Flo Elite BN
7.GE-Tospearl 145A
8.Kobo-BPD-500T
9.Dow Corning-DC 9506 Powder
10.GE-Velvesil-1111-19-372
11.Kobo-Silica Shells
过程:将D相成分的去离子水和Silica Shells混合,然后用螺旋或分散搅拌机搅拌直至达到均一化。加入剩余的D相成分,然后继续用螺旋或分散搅拌机搅拌。在夹套容器中混合A相成分,然后开始用转子定子磨搅拌。使冷水通过夹套容器再循环。将B相成分一起搅拌十分钟。将混合好的B相加入A相成分中。将C相成分加入AB相中。剪切ABC相直至它完全解附聚,而且颜料被减小至它们的主要粒径。在中等剪切下将D相乳化进入ABC相中。用扫壁搅拌混合ABCD相直至均匀。贮存在大小合适的容器中。
实施例15
适用作第二组合物的粉末粉底
A相 重量百分比
滑石 23.90
云母 17.66
云母(绢云母) 29.04
二氧化钛 11.60
尼龙-12 1.76
二氧化硅 2.64
对羟基苯甲酸丙酯,NF 0.10
对羟基苯甲酸甲酯,NF 0.30
脱氢乙酸钠,NF 0.10
红色氧化铁 0.43
黑色氧化铁 0.29
黄色氧化铁 0.50
B相
聚二甲基硅氧烷(和)三甲基甲硅烷
氧基硅酸酯 6.43
琥珀酸二辛酯 0.80
羟基硬酯酸辛酯 0.70
羟基硬脂酸胆甾醇酯 1.05
生育酚 0.01
甲氧基肉桂酸辛酯 2.69
100
用整体混合将A相成分混合(如Ribbon混合器,双锥混合器或用手),然后用高剪切混合(如锤磨机、粉磨机或切碎刀片)以分解任何颗粒附聚物。用螺旋混合器混合B相成分,然后加热至75℃。将B相成分加入A相中,然后组合使用整体和高剪切混合进行分散。
实施例16至17
硅氧烷包水的第二组合物实施例:
成分 | 实施例16 | 实施例17 | |
A1 | 环戊硅氧烷和聚二甲基硅氧烷共聚多元醇 | 9.000 | 9.000 |
A2 | 十三烷基新戊酸酯 | 6.300 | 6.300 |
A3 | 十甲基环戊硅氧烷 | 14.543 | 14.543 |
A4 | 聚乙二醇(7)月桂基醚 | 0.500 | 0.500 |
A5 | 对羟基苯甲酸丙酯 | 0.150 | 0.150 |
B1 | 二氧化钛(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 12.062 | 12.062 |
B2 | 氧化铁(CI 77492)(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 1.382 | 1.382 |
B3 | 氧化铁(CI 77491)(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 0.314 | 0.314 |
B4 | 氧化铁(CI 77499)(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 0.189 | 0.189 |
B5 | 辛烯基琥珀酸铝淀粉4 | 5.000 | 5.000 |
C1 | 去离子水 | 17.510 | 17.510 |
C2 | 聚乙烯吡咯烷酮 | 1.500 | 1.500 |
C3 | 苯氧基乙醇 | 0.250 | 0.250 |
C4 | 乙二胺四乙酸三钠盐 | 0.100 | 0.100 |
C5 | 氯化钠 | 1.000 | 1.000 |
C6 | 脱氢乙酸钠一水合物 | 0.200 | 0.200 |
D1 | 环戊硅氧烷(和)C30-45烷基十六硬脂基聚二甲基硅氧烷交联聚合物2 | ---- | 12.000 |
D2 | 环戊硅氧烷(和)C30-45烷基十六硬脂基聚二甲基硅氧烷交联聚合物(和)二氧化钛(和)氧化铁3 | 30.000 | 18.000 |
1.Kobo Products-ITT涂敷的颜料
2.General Electric Silicones-Velvesil 125
3.General Electric Silicones-1111-21-937
4.National Starch-Dry Flo Elite BN
1.在塑料桶中混合C相。提供最大的螺旋搅拌器搅拌而无空气带入。
2.将A相成分1-6加入不锈钢夹套容器中,然后开始高剪切搅拌。
3.将B相成分加入A相中,然后开始在HIGH档研磨约30分钟。
4.均匀地将C相加入容器中的AB相中。继续匀化直至可见获得整体的均匀性。
5.加入D相成分然后匀化直至达到均匀。
实施例18至21
硅氧烷包水的第一组合物实施例:
成分 | 实施例18 | 实施例19 | 实施例20 | 实施例21 | |
A1 | 十二甲基环戊硅氧烷 | 12.450 | 12.000 | 11.550 | 12.000 |
A2 | 二氧化硅1 | 2.000 | 2.000 | 2.000 | 2.000 |
A3 | 十三烷基新戊酸酯 | 5.000 | 6.000 | 5.000 | 6.000 |
A4 | 异硬脂酸异丙酯 | ---- | ---- | 3.000 | ---- |
A6 | 聚二甲基硅氧烷(500cSt) | ---- | ---- | ---- | 30.00 |
A7 | 环戊硅氧烷(和)聚二甲基硅氧烷共聚多元醇 | 8.000 | 8.900 | ---- | 8.900 |
A8 | 环戊硅氧烷(和)C30-45烷基十六硬脂基聚二甲基硅氧烷交联聚合物(87.5%)2 | 22.000 | 30.000 | 24.000 | |
A9 | 环戊硅氧烷(和)C30-45烷基十六硬脂基聚二甲基硅氧烷交联聚合物(70.0%)2 | 9.500 | ---- | ---- | ---- |
A10 | 环戊硅氧烷(和)C30-45烷基十六硬脂基聚二甲基硅氧烷交联聚合物(和)PEG/PPG 20/15聚二甲基硅氧烷3 | --- | ---- | 12.000 | ---- |
B1 | 氧化锌 | 3.000 | 3.00 | 3.000 | 3.00 |
C1 | 对羟基苯甲酸丙酯 | 0.200 | 0.200 | 0.200 | 0.200 |
C2 | 甲氧基肉桂酸辛酯 | 6.000 | 6.000 | 6.000 | 6.000 |
D1 | SD醇 | 8.500 | 8.500 | 10.000 | 8.500 |
D2 | 去离子水 | 16.050 | 16.500 | 15.950 | 16.500 |
D3 | 氯化钠 | 1.000 | 1.000 | ---- | 1.000 |
D4 | 对羟基苯甲酸甲酯 | 0.200 | 0.200 | 0.200 | 0.200 |
D5 | 甘油 | 4.000 | 4.000 | 5.000 | 4.000 |
D6 | 乙二胺四乙酸三钠盐 | 0.100 | 0.100 | 0.100 | 0.100 |
D7 | 苯氧基乙醇 | 0.400 | ---- | 0.400 | ---- |
E1 | 丙烯酸酯/C12-22烷基甲基丙烯酸酯4 | 1.600 | 1.600 | 1.600 | 1.600 |
1.Kobo Products-Silica Shells
2.General Electric Silicones-Velvesil 125
3.General Electric Silicones-1120-21-381
4.Rohm and Haas-Ailianz OPT
1.将成分D1和D5混合至大不锈钢杯中。提供最大的螺旋搅拌器搅拌而无空气带入。
2.将A和B相成分加入不锈钢容器中。高剪切搅拌15分钟或直至达到均匀。
3.将C相成分加入另一个烧杯中。手动搅拌直至对羟基苯甲酸酯溶解。
4.将C相加入配料中。继续高剪切直至均匀。
5.一旦ABC相被均匀地置入匀化器,然后加入D相并且继续均化直至达到均匀。
6.加入E相,并且用螺旋搅拌器搅拌直至外观和稠度均匀。
实施例22至23
水包硅氧烷的第二组合物实施例:
成分 | 实施例22 | 实施例23 | |
A1 | 十甲基环戊硅氧烷 | 9.145 | 9.145 |
A2 | 十二甲基环戊硅氧烷 | 2.065 | 2.065 |
A3 | 十三烷基新戊酸酯 | 8.000 | 8.000 |
A4 | PCA聚二甲基硅氧烷 | 2.000 | 2.000 |
A5 | 对羟基苯甲酸丙酯 | 0.150 | 0.150 |
A6 | 二十烷基二十二烷酸酯 | 0.300 | 0.300 |
A7 | 硬脂醇 | 0.750 | 0.750 |
B1 | 二氧化钛(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 9.075 | 9.075 |
B2 | 氧化铁(CI 77492)(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 0.810 | 0.810 |
B3 | 氧化铁(CI 77491)(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 0.262 | 0.262 |
B4 | 氧化铁(CI 77499)(和)聚甘油基-4异硬脂酸酯(和)鲸蜡基聚二甲硅氧烷共聚多元醇(和)月桂酸己酯(和)异丙基三异硬脂酸钛1 | 0.143 | 0.143 |
B5 | 二氧化硅2 | --- | 2.00 |
C1 | 去离子水 | 54.000 | 52.000 |
C2 | 对羟基苯甲酸甲酯 | 0.200 | 0.200 |
C3 | 苯氧基乙醇 | 0.500 | 0.500 |
C4 | 羟丙基淀粉磷酸盐 | 2.000 | 2.000 |
C5 | 甘油 | 2.250 | 2.250 |
C6 | 丁二醇 | 2.250 | 2.250 |
C7 | 聚乙烯吡咯烷酮 | 1.000 | 1.000 |
C8 | 乙二胺四乙酸三钠盐 | 0.100 | 0.100 |
C9 | 棕榈酸蔗糖酯(和)硬脂酸甘油酯(和)硬脂酸柠檬酸甘油酯(和)蔗糖(和)甘露聚糖(和)黄原胶3 | 2.000 | 2.000 |
C10 | 辛烯基琥珀酸铝淀粉4 | 3.000 | 3.00 |
1.Kobo Products-ITT Coated Pigments
2.Kobo Products-Silica Shells
3.Uniquima-Arlatone V-175
4.National Starch-Dry Flo Elite BN
1.用最大螺旋搅拌器混合成分C1和C9。
3.加入C相成分2、3、5、6、7、8和10。提供最大的螺旋搅拌器搅拌而无空气带入。
4.加热C相至70℃至80℃。一旦配料达到70℃至80℃,加入50%的C4。
5.将A相成分1-5加入至独立的容器中并开始匀化配料。
6.加热A相至70℃至80℃。
5.将B相加入A相中,在HIGH档剪切约20至30分钟。
6.一旦AB相达到70℃至80℃,加入A相成分6-7。
7.将AB相转移至C相中,同时螺旋搅拌。搅拌直至外观均匀。
8.用高剪切匀化配料。加入剩余50%的C4。保持直至达到均匀。
Claims (10)
1.适于以多步面部粉底产品涂敷的化妆品套盒,所述套盒的特征在于:
a.第一组合物,所述第一组合物包含:
i.安全有效量的第一化妆品有益剂;和
ii.第一美容可接受载体;和
b.第二组合物,所述第二组合物包含:
i.安全有效量的一种或多种折射指数大于2.0的着色剂;和
ii.第二美容可接受载体;
其中所述第二组合物在所述第一组合物之后被局部涂敷于面部皮肤上。
2.如权利要求1所述的化妆品套盒,其中所述第一化妆品有益剂选自吸收剂、抗痤疮活性物质、止汗剂活性物质、抗皱纹活性物质、人工晒黑剂、收敛剂、成膜剂、亲水调理剂、疏水调理剂、散光剂、脱屑剂、亮肤剂、皮肤抚慰/愈合剂、皮肤增稠剂、防晒活性物质、维生素化合物、减少黄色的颗粒、减少红色的颗粒以及它们的组合。
3.如权利要求1所述的化妆品套盒,其中所述着色剂选自氧化锌、二氧化钛、氧化铁、鸟嘌呤、胭脂红、铝粉、群青颜料、氯氧化铋、氧化铬绿、氢氧化铬绿、亚铁氰化铁、锰紫、二氧化钛、钛酸盐云母、氧化铁钛酸云母、氧化锌、云母、氰亚铁酸铵铁、二羟基丙酮、愈创烯、叶蜡石、青铜粉、铜粉、硬脂酸铝、硬脂酸钙、核黄素、硬脂酸镁、硬脂酸锌、辣椒红/辣椒玉红素、膨润土、硫酸钡、碳酸钙、硫酸钙、碳黑、碳酸镁、硅酸镁、有色二氧化硅、白垩以及它们的组合。
4.如权利要求1所述的化妆品套盒,其中所述第一组合物、所述第二组合物或所述第一组合物和所述第二组合物两者还包含安全有效量的一种或多种成膜剂,优选地所述成膜剂选自亲水成膜剂、水可分散的疏水成膜剂以及它们的组合,优选地所述成膜剂为疏水性的。
5 如权利要求1所述的化妆品套盒,其中所述第一组合物基本不含颜料。
6.如权利要求1所述的化妆品套盒,其中所述第一组合物为水包油乳液,并且所述第二组合物为硅氧烷包水乳液。
7.如权利要求1所述的化妆品套盒,其中所述第二组合物还包含化妆品有益剂,所述化妆品有益剂选自吸收剂、抗痤疮活性物质、止汗剂活性物质、抗皱纹活性物质、人工晒黑剂、收敛剂、成膜剂、亲水调理剂、疏水调理剂、散光剂、脱屑剂、亮肤剂、皮肤抚慰/愈合剂、皮肤增稠剂、防晒活性物质、维生素化合物、减少黄色的颗粒、减少红色的颗粒以及它们的组合。
8.如权利要求1所述的化妆品套盒,其中所述第一和第二组合物的产品形式选自液体、固体乳液、霜膏、露剂、粉末以及它们的组合。
9.如权利要求1所述的化妆品套盒,其中所述套盒还包含一种或多种附加组合物,所述附加组合物在所述第一和第二组合物之后相继涂敷。
10.如权利要求1所述的化妆品套盒,其中所述第一组合物、所述第二组合物或所述第一组合物和所述第二组合物两者还包含交联硅氧烷聚合物和一种或多种成膜剂。
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2003
- 2003-05-16 US US10/439,555 patent/US20040086474A1/en not_active Abandoned
- 2003-06-10 AU AU2003245430A patent/AU2003245430B2/en not_active Ceased
- 2003-06-10 WO PCT/US2003/018155 patent/WO2003105787A2/en active Application Filing
- 2003-06-10 AT AT03739072T patent/ATE422945T1/de not_active IP Right Cessation
- 2003-06-10 JP JP2004512695A patent/JP2005533059A/ja active Pending
- 2003-06-10 DE DE60326230T patent/DE60326230D1/de not_active Expired - Lifetime
- 2003-06-10 EP EP03739072A patent/EP1513491B1/en not_active Expired - Lifetime
- 2003-06-10 CN CNB038140764A patent/CN1292729C/zh not_active Expired - Fee Related
- 2003-06-10 MX MXPA04012626A patent/MXPA04012626A/es not_active Application Discontinuation
- 2003-06-10 CA CA2487803A patent/CA2487803C/en not_active Expired - Fee Related
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US8045430B2 (en) | 2002-09-30 | 2011-10-25 | Lg Electronics Inc. | Write-once type optical disc, and method and apparatus for managing defective areas on write-once type optical disc using TDMA information |
CN109044884A (zh) * | 2012-05-30 | 2018-12-21 | 诺赛尔股份有限公司 | 用于减少毛发外观的美容产品 |
CN102716060A (zh) * | 2012-07-10 | 2012-10-10 | 中国国旅贸易有限责任公司 | 松针粉-超细微晶纤维素爽身粉及其制造方法 |
CN108136229A (zh) * | 2015-10-02 | 2018-06-08 | 拜尔斯道夫股份有限公司 | 软包装的化妆品制剂 |
CN105560127A (zh) * | 2016-02-29 | 2016-05-11 | 安徽大学 | 一种天然色素cc霜及其制备方法 |
CN105560127B (zh) * | 2016-02-29 | 2018-07-27 | 安徽大学 | 一种天然色素cc霜及其制备方法 |
Also Published As
Publication number | Publication date |
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MXPA04012626A (es) | 2005-03-23 |
WO2003105787A3 (en) | 2004-03-25 |
CA2487803A1 (en) | 2003-12-24 |
JP2005533059A (ja) | 2005-11-04 |
EP1513491B1 (en) | 2009-02-18 |
US20040086474A1 (en) | 2004-05-06 |
AU2003245430B2 (en) | 2006-05-25 |
DE60326230D1 (de) | 2009-04-02 |
CA2487803C (en) | 2012-01-10 |
AU2003245430A1 (en) | 2003-12-31 |
CN1292729C (zh) | 2007-01-03 |
ATE422945T1 (de) | 2009-03-15 |
EP1513491A2 (en) | 2005-03-16 |
WO2003105787A2 (en) | 2003-12-24 |
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