CN1559446A - Antimicrobial (tincture)medicine with functons of analgesia, hemostasis and relieving-itching - Google Patents
Antimicrobial (tincture)medicine with functons of analgesia, hemostasis and relieving-itching Download PDFInfo
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- CN1559446A CN1559446A CNA2004100063473A CN200410006347A CN1559446A CN 1559446 A CN1559446 A CN 1559446A CN A2004100063473 A CNA2004100063473 A CN A2004100063473A CN 200410006347 A CN200410006347 A CN 200410006347A CN 1559446 A CN1559446 A CN 1559446A
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- propolis
- medicine
- hemostasis
- bacillus
- tincture
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- 239000003814 drug Substances 0.000 title claims abstract description 17
- 229940098465 tincture Drugs 0.000 title abstract description 5
- 230000023597 hemostasis Effects 0.000 title description 7
- 208000003251 Pruritus Diseases 0.000 title 1
- 230000036592 analgesia Effects 0.000 title 1
- 230000000845 anti-microbial effect Effects 0.000 title 1
- 241000241413 Propolis Species 0.000 claims abstract description 27
- 229940069949 propolis Drugs 0.000 claims abstract description 27
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 11
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 10
- 230000001139 anti-pruritic effect Effects 0.000 claims abstract description 10
- 239000003908 antipruritic agent Substances 0.000 claims abstract description 10
- 229920000136 polysorbate Polymers 0.000 claims abstract description 4
- 230000000202 analgesic effect Effects 0.000 claims description 7
- 230000002439 hemostatic effect Effects 0.000 claims description 6
- 239000000463 material Substances 0.000 claims 1
- 230000000146 antalgic effect Effects 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 9
- 230000003115 biocidal effect Effects 0.000 description 8
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- 208000027418 Wounds and injury Diseases 0.000 description 7
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- 244000063299 Bacillus subtilis Species 0.000 description 6
- 235000014469 Bacillus subtilis Nutrition 0.000 description 6
- 229930003935 flavonoid Natural products 0.000 description 6
- 150000002215 flavonoids Chemical class 0.000 description 6
- 235000017173 flavonoids Nutrition 0.000 description 6
- QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 description 6
- 241000191967 Staphylococcus aureus Species 0.000 description 5
- 230000035876 healing Effects 0.000 description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 241000304886 Bacilli Species 0.000 description 4
- 241000233866 Fungi Species 0.000 description 4
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- 208000002474 Tinea Diseases 0.000 description 4
- 231100000957 no side effect Toxicity 0.000 description 4
- ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 description 3
- 241000256844 Apis mellifera Species 0.000 description 3
- 241000193755 Bacillus cereus Species 0.000 description 3
- RTIXKCRFFJGDFG-UHFFFAOYSA-N Chrysin Natural products C=1C(O)=CC(O)=C(C(C=2)=O)C=1OC=2C1=CC=CC=C1 RTIXKCRFFJGDFG-UHFFFAOYSA-N 0.000 description 3
- FGUBFGWYEYFGRK-HNNXBMFYSA-N Pinocembrin Natural products Cc1cc(C)c2C(=O)C[C@H](Oc2c1)c3ccccc3 FGUBFGWYEYFGRK-HNNXBMFYSA-N 0.000 description 3
- 208000007107 Stomach Ulcer Diseases 0.000 description 3
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- 235000004883 caffeic acid Nutrition 0.000 description 3
- QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 description 3
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 description 3
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- 238000000034 method Methods 0.000 description 3
- URFCJEUYXNAHFI-ZDUSSCGKSA-N pinocembrin Chemical compound C1([C@@H]2CC(=O)C3=C(O)C=C(C=C3O2)O)=CC=CC=C1 URFCJEUYXNAHFI-ZDUSSCGKSA-N 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 150000003254 radicals Chemical class 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 208000004371 toothache Diseases 0.000 description 3
- 201000008827 tuberculosis Diseases 0.000 description 3
- 206010066995 Alveolar osteitis Diseases 0.000 description 2
- 208000006770 Ascorbic Acid Deficiency Diseases 0.000 description 2
- 241001478240 Coccus Species 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- 206010048768 Dermatosis Diseases 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 241000522215 Dipteryx odorata Species 0.000 description 2
- 208000001695 Dry Socket Diseases 0.000 description 2
- 241000186810 Erysipelothrix rhusiopathiae Species 0.000 description 2
- MZSGWZGPESCJAN-MOBFUUNNSA-N Melitric acid A Natural products O([C@@H](C(=O)O)Cc1cc(O)c(O)cc1)C(=O)/C=C/c1cc(O)c(O/C(/C(=O)O)=C/c2cc(O)c(O)cc2)cc1 MZSGWZGPESCJAN-MOBFUUNNSA-N 0.000 description 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 2
- BJYHZSNSMVEQEH-SJORKVTESA-N Pinobanksin 3-O-acetate Chemical compound C1([C@@H]2[C@H](C(C3=C(O)C=C(O)C=C3O2)=O)OC(=O)C)=CC=CC=C1 BJYHZSNSMVEQEH-SJORKVTESA-N 0.000 description 2
- 241000588767 Proteus vulgaris Species 0.000 description 2
- 241000194017 Streptococcus Species 0.000 description 2
- 241001480048 Trichophyton tonsurans Species 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 206010047623 Vitamin C deficiency Diseases 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 201000002820 alveolar periostitis Diseases 0.000 description 2
- 230000003064 anti-oxidating effect Effects 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- -1 benzyl ester Chemical class 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 239000003610 charcoal Substances 0.000 description 2
- TUJPOVKMHCLXEL-UHFFFAOYSA-N eriodictyol Natural products C1C(=O)C2=CC(O)=CC(O)=C2OC1C1=CC=C(O)C(O)=C1 TUJPOVKMHCLXEL-UHFFFAOYSA-N 0.000 description 2
- SBHXYTNGIZCORC-ZDUSSCGKSA-N eriodictyol Chemical compound C1([C@@H]2CC(=O)C3=C(O)C=C(C=C3O2)O)=CC=C(O)C(O)=C1 SBHXYTNGIZCORC-ZDUSSCGKSA-N 0.000 description 2
- 235000011797 eriodictyol Nutrition 0.000 description 2
- SBHXYTNGIZCORC-UHFFFAOYSA-N eriodyctiol Natural products O1C2=CC(O)=CC(O)=C2C(=O)CC1C1=CC=C(O)C(O)=C1 SBHXYTNGIZCORC-UHFFFAOYSA-N 0.000 description 2
- VCCRNZQBSJXYJD-UHFFFAOYSA-N galangin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=CC=C1 VCCRNZQBSJXYJD-UHFFFAOYSA-N 0.000 description 2
- 230000002949 hemolytic effect Effects 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000002980 postoperative effect Effects 0.000 description 2
- 229940007042 proteus vulgaris Drugs 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 208000010233 scurvy Diseases 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 230000035939 shock Effects 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 230000017423 tissue regeneration Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
- QTWJRLJHJPIABL-UHFFFAOYSA-N 2-methylphenol;3-methylphenol;4-methylphenol Chemical compound CC1=CC=C(O)C=C1.CC1=CC=CC(O)=C1.CC1=CC=CC=C1O QTWJRLJHJPIABL-UHFFFAOYSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 240000001624 Espostoa lanata Species 0.000 description 1
- 235000009161 Espostoa lanata Nutrition 0.000 description 1
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical class O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 1
- 206010018276 Gingival bleeding Diseases 0.000 description 1
- 208000024283 Gingival haemorrhages Diseases 0.000 description 1
- 241001299895 Microsporum ferrugineum Species 0.000 description 1
- 241000186359 Mycobacterium Species 0.000 description 1
- 241000893976 Nannizzia gypsea Species 0.000 description 1
- 241000193418 Paenibacillus larvae Species 0.000 description 1
- 208000009019 Pericoronitis Diseases 0.000 description 1
- 244000110797 Polygonum persicaria Species 0.000 description 1
- 241000588769 Proteus <enterobacteria> Species 0.000 description 1
- 201000004328 Pulpitis Diseases 0.000 description 1
- 206010037464 Pulpitis dental Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- YADZBEISHVCBSJ-UHFFFAOYSA-N [I].OCC(O)CO Chemical compound [I].OCC(O)CO YADZBEISHVCBSJ-UHFFFAOYSA-N 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000003260 anti-sepsis Effects 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 229940025250 camphora Drugs 0.000 description 1
- 239000010238 camphora Substances 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 229930003836 cresol Natural products 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000019256 formaldehyde Nutrition 0.000 description 1
- CIPSYTVGZURWPT-UHFFFAOYSA-N galangin Natural products OC1=C(Oc2cc(O)c(O)cc2C1=O)c3ccccc3 CIPSYTVGZURWPT-UHFFFAOYSA-N 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- SUYJZKRQHBQNCA-UHFFFAOYSA-N pinobanksin Natural products O1C2=CC(O)=CC(O)=C2C(=O)C(O)C1C1=CC=CC=C1 SUYJZKRQHBQNCA-UHFFFAOYSA-N 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
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- 230000002588 toxic effect Effects 0.000 description 1
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- 229940099259 vaseline Drugs 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
An antalgic, staltic, antipruritic and antibacterial medicine in the form of tincture is prepared from propolis, alcohol, glycerine, and tween.
Description
The present invention relates to a kind of medicine of analgesic hemostatic antipruritic antibacterial, but especially to toothache analgesic tincture dose medicament.
The medicine that is used for the analgesic hemostatic antipruritic antibacterial at present mainly contains: Oleum Caryophylli, Camphora, carbolic acid, iodine glycerol, deactivator (arsenicum), cresol, formaldehydes, but these drug price height, the course of treatment is long to the small number of patients toxic side effect, patient can not use by oneself and take orally, further consultation often, patient be difficult to cooperate.
The purpose of this invention is to provide a kind of medicine for the treatment of the analgesic hemostatic antipruritic antibacterial, but especially to the pain relieving of having a toothache, to pulpitis, pericoronitis, gingival hemorrhage, oral cavity burst pain, positive effect is arranged, particularly to have tooth pulled out back hemostasis, infection, avoid dry socket and postoperative wound that the remarkable result that promotes healing is arranged.The characteristics of this preparation be relieve the pain, hemostasis, antipruritic, antibacterial effect is obvious, the wound good film-forming property can well protect skin to avoid the medicine of environmental stimuli, curative effect height of the present invention, short treating period is cured highly, has no side effect.
The present invention adopts following principle to realize: the present invention adopts its effect of propolis and foundation: people use existing thousands of years of propolis, and the pontifex of ancient Egypt is being grasped the method for medicine, chemistry and system mummy, and they have gained some understanding to the anti-corrosive properties of propolis.The ancient Greek and the Roman Empire are all relevant for the record of propolis.The beginning of this century, during Knickerbocker African and British boer war (1889-1902), just once adopted " propolis vaseline " treatment wound, (1902) and think that it has the effect that promotes tissue regeneration, (1923) former Soviet Union also uses propolis ointment to control wound during patriotic war in a large number.Gigawatt Er Jinna (1947-1948) has carried out systematic study to the antibacterial activity of propolis, he finds that propolis is to staphylococcus aureus, Ba Deshi bacillus and necrosis in the gram negative bacterias such as Staphylococcus albus, Hemolytic streptococcus, bacillus rhusiopathiae suis, bacillus subtilis, charcoal subcutaneous ulcer bacillus, the bacteriostatic activity of bacillus is also very strong.La Wei (1960) finds propolis to bacillus subtilis, and proteus vulgaris and honeybee epidemic disease bacillus cereus have antibiotic property, thinks that antibacterial activity is mainly from the galangin and the pinocembrin of propolis.Ka Limowa (1961-1963) claims that propolis has the activity of anti-acid-fast bacillus, available propolis treatment tuberculosis.People (1970) such as Welland girl baby year proposition, isolating pinocembrin has very strong antibiotic property from propolis.Maze people (1975) such as is received and is detected the resistance of the various compositions of propolis to bacillus subtilis, staphylococcus aureus, colibacillus, and thinking has remarkable antibiotic property to a tonkabean acid benzyl ester and a kind of caffeic acid fat by 3-acetyl pinobanksin.Woods Deng Feierze (1976) gathers 15 propolis samples from the different local Various Seasonal of the U.S., measure in the antibacterial with its extract, 25 kinds have strong restraint, comprising bacillus larvae, Gram-negative coccus and acid-fast bacilli, other has 7 kinds of gram negative bacilli to be suppressed, and has 20 kinds to be suppressed in the fungus of 39 kinds of tests.He finds that Trichophyton has sensitivity to propolis, uses propolis treatment Trichophyton to provide foundation as dermatosis.He thinks that the caffeic acid in the propolis has antibiotic property to staphylococcus aureus, Bacillus proteus, tuberculosis mycobacterium and fungus.People such as the pillars of a house (1984) experimental results show that alcohol immersion of 1%-10% propolis or ether immersion to the achorion in the common medical mycology with paper dish method, and red mentagrophytes, floccus mentagrophyte, Microsporum ferrugineum, Microsporum gypseum, ulotrichy pityrosporion ovale, trichophyton tonsurans, brain shape tinea bacterium, purple tinea bacterium etc. all have stronger bacteriostasis.People such as A Weiduo (1974) point out, with flavonoid one eriodictyol, can prevent and treat because the acute PI that respiratory tract burn thoracic trauma and shock cause.Luo Jie (1988) points out, flavonoid in the propolis helps the healing of gastric ulcer, improve PI: play an important role to strengthening blood capillary, can prevent and treat vitamin C deficiency with vitamin C is collaborative, propolis is similar to the antioxidation of many flavonoid, can remove free radical, therefore, propolis has no side effect.The present invention adopts its effect of ethanol and foundation: the solubilized propolis also has antiinflammation.The present invention adopts Oleum Caryophylli, and it has pain relieving, is good for the stomach, antibiotic, deodorization, antisepsis.The present invention has the medicine of the effect that promotes tissue regeneration, and the present invention has antibiotic property, to staphylococcus aureus.Hemolytic streptococcus, bacillus rhusiopathiae suis, the bacteriostatic activity of estimating Ahmedabad in gram, the negative bacterium such as careless bacillus, charcoal subcutaneous ulcer bacillus and gangrenosum acne bacillus are also very strong.Bacillus subtilis, P. vulgaris and honeybee epidemic disease bacillus cereus there are resistance, think that antibacterial activity is mainly also very strong.Bacillus subtilis, proteus vulgaris and honeybee epidemic disease bacillus cereus are had resistance, can be used for treating tuberculosis, pinocembrin has very strong antibiotic property.Various compositions are to bacillus subtilis, staphylococcus aureus, escherichia coli have resistance, think 3-acetyl pinobanksin, have significantly antibiotic to a tonkabean acid benzyl ester and a kind of caffeic acid fat, mensuration is in the antibacterial, and 25 kinds of strong restraints are comprising plumelet spore bacillus, Gram-negative coccus and acid-fast bacilli, the inhibition that other has 7 kinds of gram negative bacilli to be subjected to, have 20 kinds and be suppressed in the fungus of 39 kinds of tests, finding has sensitivity to Trichophyton, for dermatosis provides foundation.To the little spore bacterium of the achorion/red mentagrophytes in the common fungus/floccus mentagrophyte rust, microsporon gypseum, ulotrichy pityrosporion ovale, trichophyton tonsurans, brain shape tinea bacterium, purple tinea bacterium has stronger inhibitory action.Flavonoid one eriodictyol can be prevented and treated because the acute pulmonary insufficiency that respiratory tract burn and shock cause.Flavonoid helps the healing of gastric ulcer, improves PI, works the effect of being sought after to strengthening blood capillary, with the collaborative vitamin C deficiency of preventing and treating of vitamin C, similar to the antioxidation of many flavonoid, can remove free radical, the medicine principle cooperation that therefore has no side effect realizes.
Owing to adopting such scheme, can make analgesic hemostatic antipruritic antibacterial of the present invention, especially can reach 99% to toothache pain relieving effective percentage, healing can reach more than 98.6%, to the remarkable result of having tooth pulled out back hemostasis, infection, avoiding dry socket and postoperative wound to have promotion to heal.The characteristics of this preparation be relieve the pain, hemostasis, antipruritic, antibacterial effect is obvious, the wound good film-forming property can well protect skin to avoid the medicine of environmental stimuli.
Below be the present invention's prescription and processing technology in detail: detailed prescription of the present invention: propolis 4 grams, 1000 milliliters of ethanol, 10 milliliters of glycerol, 10 milliliters of tweens, Oleum Caryophylli 1 gram.Processing technology of the present invention: with the medicine of alcohol-pickled propolis 4 grams, 1000 milliliters of ethanol, 10 milliliters of glycerol, 10 milliliters of tweens, after-filtration on the 20th bottling is standby gets above-mentioned synthetic tincture.According to the characteristics of this preparation be pain relieving, hemostasis, antipruritic, antibacterial effect is obvious, the wound good film-forming property can be avoided environmental stimuli by fine protection skin wound.Help the healing of gastric ulcer, improve PI, play important protective effect, can remove free radical, easy many usefulness, the principle that has no side effect strengthening blood capillary.Using method: insert cavity or be applied to the cotton balls dip in liquid medicine and suffer from hemostasis by compression.
Claims (1)
1. the medicine of an analgesic hemostatic antipruritic antibacterial is characterized in that it is to form with following materials of weight proportions medicine: propolis 4 grams, 1000 milliliters of ethanol, 10 milliliters of glycerol, 10 milliliters of tweens.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2004100063473A CN1559446A (en) | 2004-02-27 | 2004-02-27 | Antimicrobial (tincture)medicine with functons of analgesia, hemostasis and relieving-itching |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2004100063473A CN1559446A (en) | 2004-02-27 | 2004-02-27 | Antimicrobial (tincture)medicine with functons of analgesia, hemostasis and relieving-itching |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1559446A true CN1559446A (en) | 2005-01-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2004100063473A Pending CN1559446A (en) | 2004-02-27 | 2004-02-27 | Antimicrobial (tincture)medicine with functons of analgesia, hemostasis and relieving-itching |
Country Status (1)
| Country | Link |
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| CN (1) | CN1559446A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366426A (en) * | 2011-10-26 | 2012-03-07 | 江苏江大源生态生物科技有限公司 | Propolis tincture for external use and preparation method thereof |
-
2004
- 2004-02-27 CN CNA2004100063473A patent/CN1559446A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102366426A (en) * | 2011-10-26 | 2012-03-07 | 江苏江大源生态生物科技有限公司 | Propolis tincture for external use and preparation method thereof |
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