CN1429498A - Health-care food - Google Patents
Health-care food Download PDFInfo
- Publication number
- CN1429498A CN1429498A CN02157491A CN02157491A CN1429498A CN 1429498 A CN1429498 A CN 1429498A CN 02157491 A CN02157491 A CN 02157491A CN 02157491 A CN02157491 A CN 02157491A CN 1429498 A CN1429498 A CN 1429498A
- Authority
- CN
- China
- Prior art keywords
- health food
- isoflavone
- soybean isoflavone
- substance
- glucoside
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 239000000126 substance Substances 0.000 claims abstract description 29
- 235000013402 health food Nutrition 0.000 claims abstract description 26
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- 235000008696 isoflavones Nutrition 0.000 claims description 129
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- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims description 84
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- AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 1
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- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
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- 235000004867 hydroxocobalamin Nutrition 0.000 description 1
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- 229910052742 iron Inorganic materials 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
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- 150000002632 lipids Chemical class 0.000 description 1
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Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
An object of the present invention is to provide a very effective health food for supplying a pungent substance, a bitter substance or a sour substance, in particular a pungent substance, thereby refreshing a body or feeling, preventing forgetting, and intensifying weakened muscles whereby the health food is useful in treating rheumatism, etc. The present invention relates to a health food product comprising a pungent, bitter and/or sour substance, especially to a health food product comprising at least an effective amount of pungent substances.
Description
Invention field
The present invention relates to new health food.
Background technology
Will in the brain substantial is that spirit substantial is called the serotonin of brain hormone, the control of norepinephrine, corresponding to enriching of this will, voluntary muscle is activated by the excretory epinephrine that belongs to the adrenal medulla class of the pheochromocyte on adrenal medulla and the neural flesh.
Serotonin, norepinephrine, epinephrine are called biological monoamine, and they were known as the oxydasis decomposition of monoamine oxidase, MAO in the longest 3 hours or by absorptions again such as nervous tissues, secreted nearly all monoamine can be ineffective.
This is because the monoamine long duration of action causes fatigue, is that human body prevents tired exquisite mechanism.
The morbidity of depressive illness causes lacking will owing to these biological monoamine secretion capacities descend and spirit is enriched, depressive state is maintained and causes, spirit goes down sometimes, until producing intensive suicide hope.
So far, for the disposal of depressive illness, adopt passive symptomatic therapy always, promptly, take the health food that suppresses the monoamine oxidase, MAO effect or prevent the resorbent health food of these monoamines, the concentration of the monoamine of these that keep that secretion capacity descends prevents that spirit is extremely dispirited.
But because this therapy is not to be the primal therapy of purpose to eliminate biological monoamine secretion capacity this pathogenic factor that descends, so it is a kind of therapy that can only expect that in symptomatic therapy process over a long time monoamine secretion capacity can nature recovers.
But there is following shortcoming in this therapy: because monoamine always exists, the above-mentioned recovery naturally not only can further be weakened the monoamine secretion capacity, and causes easily by epinephrine sugar and lipid surplus are burnt and the physically-draining that fatigue produced that causes.
, gas is meant the function that human body is total, and this function roughly is divided into 2 kinds.The first is subjected to the function of autonomic nerve domination, is the function that each internal organs, hormone secretion, blood vessel etc. have.Another kind is the function of brain thinking, is to think deeply the instruction of sending and the function of the voluntary muscle that moves etc. by brain.
In Chinese medicine, point out for a long time, by Fill gas, the gas that showed of regulating the flow of vital energy only is meant the function of the former autonomic nerve domination.The instruction how which function in these is brought into play is that the oblongata from the foot that is positioned at brain sends.Examine and consider Fill gas medicine and not only activate certain specific internal organs and organ, and activate the function of all autonomic nerve dominations, so, can think that the application point of Fill gas medicine is not each internal organs and organ, but the oblongata in its instruction generation source.That is, the effect of Fill gas medicine is to strengthen command signal and its transmission of promotion of sending from oblongata.The present inventor finds that Fill gas medicine concentrates in internal organs etc. the body inner blood, this also is by making vasoconstriction, dilating effect performance function as one of oblongata important function, making the vasodilation of leading to the autonomic nerve dominating system and the vasoconstriction of leading to brain and brain dominating system organ is realized, its objective is the secondary role of Zuo Wei Fill gas medicine, more nutrient is transported to the part that needs.
In the past, depressive illness is less generation, but in recent years, the depressive illness sickness rate of countries in the world increases year by year, it is said that per 150 philtrums just have 1 depressive illness patient in Tokyo.
Recently, for the reason that this depressive illness sickness rate increases, the someone has delivered a very interesting opinion.
That is, it is a kind of like this saying: remove a part of region dispute, the world is away from war danger, and social order also obtains rectifying, and the chance that meets with an accident has also reduced, and human body performs the needs of dealing with dangerous spirit preparation not to have been had substantially yet.
For this reason, the excretory needs of biogenic amine also extremely reduce, and its secretion capacity is degenerated, and its result is easy to produce depressive illness.
If the words that this saying is correct, if then adopt the artificial excretory means of biological monoamine that promote, for example 1 day 1 time, just can prevent the morbidity of depressive illness, the depressive illness patient that the biogenic amine secretion capacity is descended recovers the secretion capacity of biological monoamine, and the probability of depressive illness recovery from illness also can produce.
Have again, along with the age constantly increases, proctoptosis and foot, waist, arm pain can appear, this just is understood that it is because in these parts always, disturbance of blood circulation or resultant inflammation cause, if be commonly used for certain medicine of getting rid of disturbance of blood circulation with being entirely separately, then the improvement of these diseases is insufficient.
The reason of these obstacles is owing to brain instruction transmits insufficient causing to the part, because the incomplete transmission of brain instruction, the generation of disturbance of blood circulation and inflammation is the problem that can not proper motion produces owing to muscle.
Though all muscular disorders are not only insufficient the causing of transmission of brain instruction, it is generally acknowledged that the major part of this obstacle is the insufficient of brain instruction transmission.Find with advancing age that particularly the muscular disorders such as pain of produced simultaneously pain in the lumbar region, extremity are easy to by improving the eliminatings such as curcumin that the brain instruction transmits.
The present invention is based on this new theory of medicine, carried out the exploitation of medicine, purpose is to provide has extremely effectively medicine of the action of muscles of enhancing, anti-inflammatory effect.
The present invention is based on this new theory of medicine, carried out the exploitation of health food, purpose is at depressive illness etc., provides extremely effectively health food to the people of off color.
Summary of the invention
The present invention relates to spicy substance, bitter substance or sour odour material, particularly contain the health food of spicy substance, bitter substance or the sour odour material of food.
Spicy substance of the present invention, bitter substance or sour odour material be spicy substance preferably.
Spicy substance is the curcumin of Radix Curcumae preferably
[changing 1]
The capsaicin of Fructus Capsici
[changing 2]
Piperic piperine
[changing 3]
The (4-hydroxy-3-methoxyphenyl)ethyl methyl ketone of Rhizoma Zingiberis Recens
[changing 4]
[6]-shogaol of Rhizoma Zingiberis Recens
[changing 5]
[6]-gingerol of Rhizoma Zingiberis Recens
[changing 6]
Preferred especially curcumin.
As bitter substance, preferred swertiamarin, gentiopicrin, loganin.
Sour odour material optimization citric acid, lactic acid.
One daily intake of spicy substance is 1-1000mg preferably, is 10-300mg better, is preferably 20-70mg.
Daily intake when they use separately is good with 100-800mg, is preferably 300-500mg.
In addition, when having the Chinese medicine preparation of the effect set upright with decoction of ten powerful tonics etc. or the daily intake of Chinese medicine and time spent is preferably 100-200mg.
As long as it is just passable that the present invention contains spicy substance, bitter substance or sour odour material; but be preferably; contain isoflavone, acyl group isoflavone and isoflavone glucoside, isoflavone, acyl group isoflavone and isoflavone glucoside be contained soybean isoflavone, acyl group soybean isoflavone and soybean isoflavone glucoside in the Semen sojae atricolor preferably.
The acyl group of acyl group isoflavone is good with the sour residue of the saturated or unsaturated fatty acid of 2-18 carbon atom, preferably acetic acid, Palmic acid, stearic sour residue.In addition, acidylate can be with the whole acidylates of the hydroxyl of isoflavone, also can be with one part of hydroxyl acidylate.
Owing to can increase oil-soluble by acidylate, therefore, be under the situation of oil preparation at preparation, can dissolve a large amount of acyl group isoflavone.
The preferred 1-500mg of one daily intake of isoflavone, acyl group isoflavone and isoflavone glucoside, more preferably 5-200mg, especially preferably 10-100mg.
The preferred 1-1000mg of one daily dose of cholic acid, more preferably 2-300mg, especially preferably 10-100mg.
As long as it is just passable that the present invention contains spicy substance, bitter thing material or sour odour material; but be preferably; contain cholic acid and/or scymnol and/or scymnol ester, preferably contain cholic acid and/or scymnol and/or scymnol ester and isoflavone and/or acyl group isoflavone and/or isoflavone glucoside.
In addition, when using isoflavone, acyl group isoflavone and isoflavone glucoside, preferably add cholic acid.
The preferred 1-1000mg of one daily dose of cholic acid, more preferably 2-300mg, especially preferably 10-100mg.
The preferred 0.1-100mg of one daily intake of scymnol and/or scymnol ester, more preferably 0.1-50mg, especially preferably 0.3-10mg.
As other composition, use common health food, use vitamins, heme iron, european plum extract, crude drug etc.
As crude drug, preferably have the effect set upright, for example, can activate crude drug and the digestive crude drug of the function of the organ that is subjected to the autonomic nerve domination, gland, blood vessel.
The known crude drug that can activate the function of the organ that is subjected to autonomic nerve domination, gland, blood vessel has more than 10 kinds, for example, Radix Ginseng etc. is arranged, and is that several effective ingredient of these crude drugs of representative are understood with the Radix Ginseng.
Therefore, preferably add these effective ingredient.By these effective ingredient of further interpolation, can bring into play the function of human body activation.
As such crude drug, special preferably ginseng, Radix Codonopsis, Radix Pseudostellariae, Radix Panacis Quinquefolii, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Radix Glycyrrhizae, Fructus Jujubae, glue maltosemalt sugar, Rhizoma Polygonati, lance asiabell root etc.
In addition, preferably add digestive crude drug, as Fructus Crataegi, Massa Medicata Fermentata, Semen Raphani, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Endothelium Corneum Gigeriae Galli, Resina Ferulae etc.
Scymnol and/or scymnol ester are included in the bile of shark.
Scymnol is represented by following structural formula.
In addition, scymnol sulfuric ester sodium salt is represented by following structural formula.
In addition, a kind of raw material that also has that uses in the present invention is isoflavone, acyl group isoflavone and isoflavone glucoside.
The contained effective ingredient that meets this purpose is several isoflavone such as daidzein, Glycitein (glycitein), genistein of several isoflavone glucosides such as daidzin, Glycitein glycosides (glycitin), genistin or its aglycone in the Semen sojae atricolor.
Semen sojae atricolor is a raw material of making soybean oil, and the requirement of soybean oil is big, and its by-product of soybean dregs of rice are also a large amount of simultaneously to be produced.Though the part of soybean meal is used as the manufacturing raw material of soybean protein (a kind of raw-food material), mainly as fertilizer, feedstuff, its price is extremely low.With the soybean meal that is similar to trade waste is raw material, can high-purity and make soybean isoflavone, acyl group soybean isoflavone and soybean isoflavone glucoside at an easy rate.
Health food of the present invention can as blended material, can use lactose, starch, plant wet goods with common powder, solid agent and liquor picked-up.
Embodiment
Specify the present invention below.
The purity of the soybean isoflavone that uses, acyl group soybean isoflavone, soybean isoflavone glucoside is 40%.
Except pure product, the purity of the cholic acid of use is 90%.
Embodiment 1 powder
Curcumin 45mg
Scymnol 1mg
Soybean isoflavone 125mg
Lactose 800mg
Corn starch is an amount of
Magnesium stearate 10mg
Add up to 2000mg
(1 bag 1g, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make powder.
Embodiment 2 granules
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Lactose 1500mg
Corn starch is an amount of
Magnesium stearate 10mg
Add up to 2000mg
(1 bag 1g, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make granule.
Embodiment 3 tablets
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Crystalline cellulose is an amount of
Lactose 140mg
Magnesium stearate 6mg
Pulvis Talci 3mg
Add up to 1120mg
(1 280mg, 1 time 2,1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make tablet.
Embodiment 4 tablets
Curcumin 45mg
Scymnol 1mg
Soybean isoflavone 250mg
Radix Ginseng end 2000mg
Lactose 886mg
Crystalline cellulose is an amount of
Carboxymethylcellulose calcium 320mg
Hydroxy propyl cellulose 558mg
Carplex
(trade name, a kind of synthetic silica, the wild 30mg of Japanese salt
Justice Pharmaceutical Co., Ltd product)
Magnesium stearate 55mg
Add up to 5600mg
(1 280mg, 1 time 5,1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make tablet.
Embodiment 5 hard capsules
Curcumin 45mg
Scymnol 1mg
Soybean isoflavone 125mg
Lactose 218mg
Corn starch is an amount of
Magnesium stearate 6mg
Add up to 1150mg
(No. 1 capsule/4 capsule, 12 capsule, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make hard capsule.
Embodiment 6 soft capsules
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Cod liver oil 80mg
Tocopherol acetate 5mg
Radix Ginseng extract 200mg
Cera Flava 55mg
Appropriate amount of edible oil
Add up to 1200mg
(1 day 4 capsule)
Similarly, can use acyl group soybean isoflavone, soybean isoflavone glucoside to replace soybean isoflavone to make soft capsule.
Embodiment 7 potus
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Korean ginseng extract 10mg
Radix Rehmanniae extract 10mg
Lac regis apis 100mg
Thiamine nitrate 10mg
Riboflavin sodium phosphate 5mg
Pyridoxine Hydrochloride 10mg
Caffeine Anhydrous 50mg
Ethanol 1.2mL
Ethylparaben 4mg
Distilled water is an amount of
Add up to the 50mL/ bottle
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make potus.
Embodiment 8 vitamin compatibilities (hard capsule)
Curcumin 45mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Thiamine hydrochloride 25mg
Pyridoxine Hydrochloride 10mg
Riboflavin 10mg
Vitamin B12 12 μ g
Nicotiamide 20mg
Calcium pantothenate 20mg
Ascorbic acid 60mg
L-aminothiopropionic acid 10mg
Lactose 263mg
Magnesium stearate 6mg
Corn starch is an amount of
Add up to 1150mg
(1 2 capsule, 1 day 2 times)
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make hard capsule.
Embodiment 9 powders
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Corn starch is an amount of
Light anhydrous silicic acid 5mg
Magnesium stearate 10mg
Add up to 4000mg
(1 bag 2g, 1 day 2 times)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make powder.
Embodiment 10 granules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Corn starch 800mg
Crystalline cellulose 300mg
Light anhydrous silicic acid 5mg
Magnesium stearate 10mg
Add up to 4000mg
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make granule.
Embodiment 11 spheroidal particle
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 515mg
Corn starch is an amount of
Cold prunus mume (sieb.) sieb.et zucc. powder 500mg
Crystalline cellulose 400mg
Add up to 2000mg
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make spheroidal particle.
Embodiment 12 tablets
Curcumin 45mg
Cholic acid 140mg
Soybean isoflavone glucoside 280mg
Lactose 4000mg
Carboxymethylcellulose calcium 320mg
Hydroxypropyl cellulose 74mg
Crystalline cellulose is an amount of
Carplex
?????????????????????30mg
Magnesium stearate 10mg
Add up to 5484mg
(1 280g, 1 time 5,1 day 2 times)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make tablet.
Embodiment 13 hard capsules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Corn starch is an amount of
Magnesium stearate 9mg
Add up to 1153mg
(No. 1 capsule 1 day 4)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make hard capsule.
Embodiment 14 soft capsules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Cera Flava 55mg
Appropriate amount of edible oil
Add up to 1200mg
(1 day 4 capsule)
Similarly, can use soybean isoflavone, acyl group soybean isoflavone to replace soybean isoflavone glucoside to make soft capsule.Embodiment 15 potus
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Korean ginseng extract 1500mg
Arillus Longan extract 100mg
Fructus Schisandrae Chinensis fluid extract 300mg
Lac regis apis 150mg
Riboflavin sodium phosphate 10mg
Ethanol 1.2ml
P-hydroxybenzoic acid 4mg
Distilled water is an amount of
Add up to 50ml
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make potus.
Embodiment 16 granules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Thiamine hydrochloride 10mg
Pyridoxine Hydrochloride 100mg
Hydrochloric acid hydroxocobalamin 1.027mg
Tocopherol acetate 100mg
Lactose 2700mg
Crystalline cellulose 300mg
Light anhydrous silicic acid 5mg
Magnesium stearate 10mg
Corn starch is an amount of
Add up to 4000mg
(1 bag 2g, 1 day 2 times)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make granule.
Embodiment 17 capsules
Curcumin 45mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Vitamin A oil 4mg
Cholecalciferol 0.005mg
Tocopherol acetate 10mg
Vitamin C 600mg
Crystalline cellulose 250mg
Magnesium stearate 6mg
Corn starch is an amount of
Add up to 1150mg
(No. 1 capsule, 1 day 4)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make capsule.
Embodiment 18 powders
Curcumin 30mg
Scymnol 1mg
Soybean isoflavone 125mg
Lactose 800mg
Corn starch is an amount of
Magnesium stearate 10mg
Add up to 2000mg
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make powder.Embodiment 19 granules
Curcumin 30mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Lactose 1500mg
Corn starch is an amount of
Magnesium stearate 10mg
Add up to 2000mg
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make granule.
Embodiment 20 tablets
Curcumin 25mg
Scymnol 1mg
Soybean isoflavone 250mg
Radix Ginseng end 2000mg
Lactose 886mg
Crystalline cellulose is an amount of
Carboxymethylcellulose calcium 320mg
Hydroxypropyl cellulose 558mg
Carplex
?????????????????30mg
Magnesium stearate 55mg
Add up to 5600mg
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make tablet.
Embodiment 21 soft capsules
Curcumin 25mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Cod liver oil 80mg
Tocopherol acetate 5mg
Radix Ginseng extract 200mg
Cera Flava 55mg
Appropriate amount of edible oil
Add up to 1200mg
Similarly, can use acyl group soybean isoflavone, soybean isoflavone glucoside to replace soybean isoflavone to make soft capsule.
Embodiment 22 potus
Curcumin 30mg
Scymnol sodium sulfovinate 1mg
Soybean isoflavone 125mg
Korean ginseng extract 10mg
Radix Rehmanniae extract 10mg
Lac regis apis 100mg
Thiamine nitrate 10mg
Riboflavin sodium phosphate 5mg
Pyridoxine hydrochloride 10mg
Caffeine Anhydrous 50mg
Ethanol 1.2L
Ethylparaben 4mg
Distilled water is an amount of
Add up to the 50mL/ bottle
Similarly, can use soybean isoflavone glucoside to replace soybean isoflavone to make potus.
Embodiment 23 powders
Curcumin 30mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Corn starch is an amount of
Light anhydrous silicic acid 5mg
Magnesium stearate 10mg
Add up to 4000mg
(1 bag 2g, 1 day 2 times)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make powder.
Embodiment 24 granules
Curcumin 25mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Lactose 2700mg
Corn starch is an amount of
Crystalline cellulose 300mg
Light anhydrous silicic acid 5mg
Magnesium stearate 10mg
Add up to 4000mg
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make granule.
Embodiment 25 tablets
Curcumin 30mg
Cholic acid 140mg
Soybean isoflavone glucoside 280mg
Lactose 4000mg
Carboxymethylcellulose calcium 320mg
Hydroxypropyl cellulose 74mg
Crystalline cellulose is an amount of
Carplex
????????????????????30mg
Magnesium stearate 10mg
Add up to 5484mg
(1 280mg, 1 time 5,1 day 2 times)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make tablet.
Embodiment 26 hard capsules
Curcumin 25mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Corn starch is an amount of
Magnesium stearate 9mg
Add up to 1153mg
(No. 1 capsule, 1 day 4)
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make hard capsule.
Embodiment 27 potus
Curcumin 30mg
Cholic acid 60mg
Soybean isoflavone glucoside 125mg
Korean ginseng extract 1500mg
Arillus Longan extract 100mg
Fructus Schisandrae Chinensis fluid extract 300mg
Lac regis apis 150mg
Riboflavin sodium phosphate 10mg
Ethanol 1.2ml
P-hydroxybenzoic acid 4mg
Distilled water is an amount of
Add up to 50ml
Similarly, can use soybean isoflavone to replace soybean isoflavone glucoside to make potus.
Though do not carry out the research of the adrenaline secretion facilitation of relevant curcumin, (4-hydroxy-3-methoxyphenyl)ethyl methyl ketone, shogaol, in the zoopery of using Mus, concentration of glucose significantly rises in the blood, can confirm the existence of adrenaline secretion facilitation thus.
Allow 10 people of preparation of China commonly used take following medicine continuously: 3 in the lactose tablet (every 250mg) 1 day that contains 15mg curcumin, 20mg cholic acid, 40mg soybean isoflavone glucoside with the effect set upright, curcumin every day 1 time, each 45mg the results are shown in the following table.
Table 1
| Age | Sex | Condition of illness | Medicine commonly used | The history of being in hospital | Effect | |||
| Antidepressant is neat | The spirit stabilizing agent | The sleep medicine | ||||||
| ??1 | ??51 | The man | Serious depression, uneasiness | ??○ | ????○ | ???○ | ??○ | ??◎ |
| ??2 | ??38 | The man | Insomnia, uneasiness, impatience | ??○ | ????○ | ???○ | ??○ | ??○ |
| ??3 | ??51 | The man | Insomnia, uneasiness | ??× | ????× | ???× | ??× | ??- |
| ??4 | ??30 | The woman | Insomnia, uneasiness, depression | ??○ | ????○ | ???○ | ??× | ??◎ |
| ??5 | ??18 | The woman | Insomnia, uneasiness, impatience | ??× | ????× | ???× | ??× | ??◎ |
| ??6 | ??76 | The man | Impatient | ??× | ????× | ???× | ??× | ??○ |
| ??7 | ??74 | The woman | Strong uneasy, insomnia, impatience | ??× | ????× | ???× | ??× | ??○ |
| ??8 | ??48 | The woman | Depression, hypersomnia | ??○ | ????○ | ???× | ??× | ??◎ |
| ??9 | ??48 | The man | Be intended to go down impatience, major depression | ??× | ????× | ???× | ??× | ??◎ |
| ??10 | ??39 | The woman | Major depression, insomnia, uneasiness | ??× | ????× | ???× | ??× | ??◎ |
※ patient is diagnosed as depressive illness by medical practitioner
※ is about effect, and zero: effectively, ◎: significantly ,-: under observation
As above shown in the table, effective percentage is 90%, and the produce effects example reaches 60%.
According to this result, demonstrate the good result who it is generally acknowledged that the depressive illness that can not cure can be fully recovered.
Example shown in the table is back 2 months result of beginning that takes medicine, depressive illness has or not that sending out still needs again wants long-term observation, but the fact is, the user of many curcumins has returned to the state that can cross substantially near normal person's daily life, this proof, health food of the present invention is extremely effective as making refreshed food.After the 250mg lactose tablet administration that contains 1mg scymnol sodium sulfovinate (replacement cholic acid), can obtain same result.
In addition, give to show granule by the climacteric worry that causes of obstacle, depressed mood, disease such as dizzy 12 and 14 women's administration embodiment 2 and embodiment 10, as curcumin, administration every day 45mg, took back 5 days, 5 and 6 worries, depressed mood, dizzy improving are arranged respectively.In addition, after 3 weeks, add up to 11 and 12 to improve respectively.
In addition, give the granule of 10 patient's administration embodiment 2 of often forgetful alzheimer disease last stage, 7 forgetful improving behind the granule of administration embodiment 10, can obtain same result.In addition, also effective for Alzheimer's disease.
Anti-climacteric obstacle agent of the present invention, anti-senile dementia agent, anti-Alzheimer's disease agent have proved that the curative as treatment climacteric obstacle, senile dementia, Alzheimer's disease is extremely effective.
For curcumin, commercially available have a highly purified curcumin, is easy to obtain.
Take capsule 1 day 1 time for the depressive illness patient, this capsule is by 50mg capsaicin and lactose are doubly loose, and and isoflavone glucoside carry out capsule with cholic acid and fill and make.
After a few days, effect is theatrical to be manifested, and has roughly broken away from depressive state after 1 week.
In addition, the capsaicin pungent is strong.
Take the tablet 1 day 1 time of embodiment 20.
Thus, along with the age increases, 83 years old male walking easily of step property difficulty, proctoptosis severity has also broken away from proctoptosis, can oneself feel the action of anal sphincter clearly, by 1 month try out, obviously improve, and 63 years old male of stair activity difficulty be stair activity like a cork, by 1 month try out, obviously improve.In addition, the tablet of embodiment 25 also has same effect.
If these knots are bright only to be the such pharmacological effect of the active improvement of local muscle, in the result in the America and Europe who uses curcumin and Okinawa, should comprise such information, but unprecedented, this is because the brain instruction that the result of brain thinking sends causes to local transmission is undesired.
In doctor trained in Western medicine, though it is to be caused by these partial disturbance of blood circulation and its inflammation of tying bright generation that the pain of proctoptosis and foot, waist, arm can only be interpreted as, but use separately when having cooperated scymnol with the effect of abundant eliminating disturbance of blood circulation, isoflavone, cholic acid, because it is insufficient to improve these condition of illness, the reason of these obstacles can be understood as because brain instruction causes to local transmission is insufficient, the generation of disturbance of blood circulation and inflammation is that the incomplete transmission owing to brain instruction makes the muscle can not regular event, so produced obstacle.
In addition, take for each 5 patient of men and women in 60-75 year of muscular disorders such as telling the lumbago that produces with advancing age, brothers' pain, proctoptosis after, these condition of illness improve.Muscular disorders generally speaking is not insufficient the causing of brain instruction transmission, and transmission is insufficient but the major part of this obstacle is the brain instruction.
The merging of isoflavone, cholic acid, scymnol, curcumin etc. is used owing to have the effect that improves cerebration, can remove muscular disorders, concerning the advanced age person, can be one and seek and good news that spirit, muscle power youthen together.In addition, this prescription has remarkable result for arthritis such as rheumatism, particularly performance effect greatly in prevention.
For curcumin, commercially available highly purified curcumin is arranged, be easy to obtain.
Use the 30mg capsaicin to replace the curcumin of embodiment 18,, take for the person at advanced age of 76 years old and 83 years old by 1 administration in 1 day.After a few days, effect is theatrical to be manifested, after 1 week, effective to muscle deterioration, arthritis, rheumatism etc.
The present invention has can provide healthy food such excellent results by picked-up spicy substance, bitter substance or sour odour material, and this healthy food makes refreshed, prevent forgetful, strengthen the muscle of degenerating, be effective for rheumatism etc.
Claims (12)
1. a health food is characterized in that, contains spicy substance, bitter substance or sour odour material.
2. health food according to claim 1 is characterized in that described spicy substance, bitter substance or sour odour material are food.
3. health food according to claim 1 and 2 is characterized in that described spicy substance, bitter substance or sour odour material are spicy substances.
4. according to each described health food among the claim 1-3, it is characterized in that described spicy substance is a curcumin.
5. according to each described health food among the claim 1-4, it is characterized in that it contains cholic acid and/or scymnol and/or scymnol ester.
6. according to each described health food among the claim 1-5, it is characterized in that it contains isoflavone and/or acyl group isoflavone and/or isoflavone glucoside.
7. health food according to claim 6 is characterized in that, described isoflavone, acyl group isoflavone and isoflavone glucoside are soybean isoflavone, acyl group soybean isoflavone and soybean isoflavone glucoside.
8. according to each described health food among the claim 1-7, it is characterized in that, added vitamin preparation.
9. according to each described health food among the claim 1-8, it is characterized in that, added crude drug.
10. health food according to claim 9 is characterized in that described crude drug has the effect of setting upright.
11. health food according to claim 10 is characterized in that, described crude drug is more than one in Radix Ginseng, Radix Codonopsis, Radix Pseudostellariae, Radix Panacis Quinquefolii, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Radix Glycyrrhizae, Fructus Jujubae, glue maltosemalt sugar, Rhizoma Polygonati, the lance asiabell root.
12., it is characterized in that described crude drug is more than one in Fructus Crataegi, Massa Medicata Fermentata, Semen Raphani, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Endothelium Corneum Gigeriae Galli, the Resina Ferulae according to claim 10 or 11 described health food.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001384860 | 2001-12-18 | ||
| JP2001384860 | 2001-12-18 | ||
| JP2002042639A JP4609875B2 (en) | 2001-07-31 | 2002-02-20 | healthy food |
| JP200242639 | 2002-02-20 |
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| CN1327788C CN1327788C (en) | 2007-07-25 |
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| CN109966448A (en) * | 2017-01-05 | 2019-07-05 | 拉维·拉玛姆西·伊耶 | Topical herbal compositions for muscle and joint health, fatigue recovery, and pain management |
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| CN1194843A (en) * | 1997-04-01 | 1998-10-07 | 李恩洪 | Method for producing green health medicine |
| JP3920969B2 (en) * | 1997-08-04 | 2007-05-30 | 雪印乳業株式会社 | Nutritional composition |
| CN1273788A (en) * | 1999-05-15 | 2000-11-22 | 马锡洪 | Snack series |
| DE19956848A1 (en) * | 1999-11-26 | 2001-05-31 | Basf Ag | Curcumin formulations |
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