CN1265710C - Iodate composition and its application in environmental sterilization - Google Patents

Abstract

The invention provides a new generation of environment-friendly disinfectant composition which is very stable in neutral water medium and acidic water solution, has no obvious irritation, is safe, efficient and has no secondary pollution and its application. The composition consists of SF raw powder or sodium periodate, weak acid and pure water. The composition can be applied to environmental disinfection, and is widely used in public places such as canteens, shopping malls, hospitals, schools, laboratories, and families, as well as in special industries such as pharmaceuticals and environmental protection, and is especially suitable for killing atypical pneumonia bacteria. Sterilization and disinfection.

Description

Iodine salt composition and its application in environmental disinfection

technical field

The invention relates to an iodate composition and its application in environmental disinfection.

Background technique

Disinfectants can be divided into sterilizers, high-efficiency disinfectants, medium-efficiency disinfectants, and low-efficiency disinfectants. Sterilizer: A preparation that can kill all microorganisms to meet the sterilization requirements. Including formaldehyde, glutaraldehyde, ethylene oxide, peracetic acid, hydrogen peroxide, chlorine dioxide, etc. High-efficiency disinfectant: a preparation that can kill all bacterial propagules (including mycobacteria), viruses, fungi and their spores, etc., and has a certain killing effect on bacterial spores, meeting the requirements of high-level disinfection. Including chlorine-containing disinfectants, ozone, methylhydantoin compounds, double-chain quaternary ammonium salts, etc. Medium-efficiency disinfectant: a preparation that can only kill microorganisms such as mycobacteria, fungi, viruses, and bacterial propagules, and meet the disinfection requirements. Including iodine-containing disinfectants, alcohol-based disinfectants, phenol-based disinfectants, etc. Low-efficiency disinfectant: refers to a preparation that can only kill bacterial propagules and lipophilic viruses and meet the requirements of disinfectants. Including quaternary ammonium salt disinfectants such as benzalkonium bromide, biguanide disinfectants such as chlorhexidine (chlorhexidine), metal ion disinfectants such as mercury, silver and copper, and Chinese herbal medicine disinfectants.

The more commonly used chemical disinfectants include: Peroxide disinfectants: Due to their strong oxidizing ability, various microorganisms are very sensitive to them and can kill all microorganisms. Such disinfectants include hydrogen peroxide (ranging from 30% to 90%), peracetic acid (18% to 20%), chlorine dioxide, and ozone, among others. Due to their unstable chemical properties, they need to be used and prepared immediately, which is inconvenient to use, and because of their strong oxidizing ability, they can irritate, damage skin and mucous membranes, and corrode articles at high concentrations. Among them, peracetic acid is often used for virus-contaminated items or skin disinfection, and can be used for air disinfection in unmanned environments. Chlorine dioxide can be used to disinfect the surface of objects. Ozone is also a strong oxidant. Its bactericidal effect is more obvious when it is dissolved in water. It is often used for water disinfection. When disinfecting drinking water, the amount of ozone added is 0.5 to 1.5 mg per liter, and the amount of residual ozone in water is 0.1 to 0.5 mg per liter to maintain 10 Minutes can meet the disinfection requirements. When the water quality is poor, the amount of ozone added should be increased. At present, peracetic acid disinfectants widely used in the market generally have disadvantages such as corrosion to articles, bleaching, strong irritation to human skin and respiratory mucous membranes, volatile, unstable, rapid concentration drop during storage, and inconvenient use. .

Chlorine-containing disinfectant: refers to a disinfectant that dissolves in water to produce hypochlorous acid with microbicidal activity, and its active microbicidal ingredients are often represented by available chlorine. Hypochlorous acid has a small molecular weight, and it is easy to diffuse to the surface of bacteria, and penetrate the cell membrane into the bacteria, oxidizing the bacteria protein and causing the death of bacteria. Chlorine-based disinfectants kill a wide range of microorganisms, including bacterial propagules, viruses, fungi, tubercle bacilli, and the most resistant bacterial spores. Such disinfectants include: inorganic chlorine compounds such as sodium hypochlorite (10% to 20%), bleaching powder (25%), bleaching powder (mainly calcium hypochlorite, 80% to 85%), chlorinated trisodium phosphate ( 3% to 5%); organic chlorine compounds, such as sodium dichloroisocyanurate (60% to 64%), trichloroisocyanuric acid (87% to 90%), ammonium chloride T (24%) and other inorganic chlorine properties Unstable, easily affected by light, heat and humidity, and loses its active ingredients. Organic chlorine is relatively stable, but it is unstable after being dissolved in water. Their antimicrobial effect is obviously affected by the concentration and action time. The disinfection effect can be significantly reduced when organic matter (such as blood, saliva and excrement) is present. This type of disinfectant is often used for disinfection of the environment, surface of objects, tableware, drinking water, sewage, excrement, garbage, etc. CN1293540A discloses a weakly acidic disinfectant. Under weakly acidic conditions, after being dissolved in water, it produces stable hypochlorous acid or chlorous acid with high bactericidal efficacy. The concentration of available chlorine in use can be reduced to 10-500ppm between. High-concentration chlorine-containing disinfectants have obvious irritating effects on the mucous membranes and skin of the human respiratory tract, corrode and bleach objects, and can pollute the environment when used in large quantities.

Iodine-containing disinfectants: These include tincture of iodine and povidone iodine, which kill microbial proteins by halogenation. It can kill bacterial propagules, fungi and some viruses. It can be used for disinfection of skin and mucous membranes, and it is often used for surgical hand disinfection in hospitals. Generally, the concentration of tincture of iodine is 2%, and that of povidone iodine is 0.3% to 0.5%. Iodophor disinfectant is the product of the combination of iodine and polyvinyl pyrrolidone. It leaks into the liquid added with 10% KCl. K and I have strong affinity to generate KI. High concentration of KI has a strong effect on muscles. The stimulating effect, and the free carrier, polyvinylpyrrolidone, can only be taken orally and cannot be injected into the vein. In addition, iodophor is a disinfectant for external use, which contains impurities, and the carrier polyvinylpyrrolidone is a soapy substance. After entering the liquid, foams of various sizes can appear after slight shock. In addition, the above-mentioned iodine-containing disinfectants are generally colored, and iodine is easy to sublimate and has a short validity period, so it is generally limited to skin disinfection. The complexed iodine liquid disinfectant disclosed in CN 1114527A contains 0.05-4 (weight percent) iodine, 1.0-40 (weight percent) polyethylene glycol, and 0.1-4 (weight percent) fatty alcohol polyoxyethylene ether ,Deionized water

Contents of the invention

Facing the sudden national catastrophe of "SARS", the problem to be solved by the present invention is to provide a new product that is very stable in neutral aqueous medium and acidic aqueous solution, safe, efficient and free of secondary pollution without significant irritation. A generation of environmentally friendly disinfectant products and their applications.

The invention provides a kind of iodate composition, and it contains following components:

Periodate, metaperiodate or iodate of alkali metal 0.1-2.5% (by weight)

Weak acid 0～1.0% (by weight)

Pure water 96.5～99.9% (by weight)

The above-mentioned disinfectant composition of recommendation, it contains following components:

Periodate, metaperiodate or iodate of alkali metal 0.2-1.5% (by weight)

Weak acid 0～1.0% (by weight)

Pure water 97.5～99.8% (by weight)

The above-mentioned disinfectant composition of recommendation, it contains following components:

Periodate, metaperiodate or iodate of alkali metal 0.2～1.5% (by weight)

Pure water 98.5～99.8% (by weight)

The above-mentioned disinfectant composition of recommendation, it contains following components:

Periodate, metaperiodate or iodate of alkali metal 0.2～1.5% (by weight)

Acetic acid 0.2～1.0% (by weight)

Pure water 97.5～99.6% (by weight)

Described alkali metal is recommended as sodium, potassium, and the periodate, metaperiodate or iodate of alkali metal is recommended as sodium periodate, sodium metaperiodate, sodium iodate, potassium periodate, Potassium metaperiodate or potassium iodate, the weak acid is C1-C6 organic carboxylic acid, citric acid, especially acetic acid is recommended.

The recommended pH value of the above composition is 2-6.5. The above composition can also be used by diluting 1 to 5 times with water.

Conventional additives suitable for disinfectants such as perfumes and other low-carbon chain ester perfumes such as ethyl acetate can also be added to the above composition. C2-C8 esters are recommended.

There is no special limitation on the production method of the composition of the present invention, and it can be prepared by mixing the above-mentioned components simultaneously or in stages, or mixing the above-mentioned components with conventional additives of disinfectants simultaneously or in stages.

The present invention also provides a new application of the above composition, that is, for environment disinfection. The composition of the invention is suitable for sterilization and disinfection in public places such as canteens, shopping malls, hospitals, schools, laboratories, and families, as well as special industries such as pharmaceuticals and environmental protection. It is especially recommended that the composition of the present invention be used for sterilization and disinfection against atypical pneumonia bacteria. Can kill germs within 1 minute.

The invention provides a strong sterilizing and disinfecting agent containing iodine, which can break the molecular bonds of organic compounds, fungi and toxins within 15-30 seconds, and is non-toxic and has no side effects.

The composition of the present invention overcomes the ubiquitous peracetic acid disinfectants that corrode and bleach articles, have strong irritation to human skin and respiratory mucous membranes, are volatile and unstable, and the concentration drops rapidly during storage, making it inconvenient to use. and other shortcomings. At the same time, it also overcomes the shortcomings of easy sublimation, short validity period and limited use of common iodine-containing disinfectants. As a disinfectant, the composition is very stable in neutral aqueous medium and acidic aqueous solution, and has no obvious irritation, and is a new generation of environmentally friendly disinfectant product with safety, high efficiency and no secondary pollution. It can be widely used in the sterilization and disinfection of public places such as canteens, shopping malls, hospitals, secondary laboratories of schools, and families, as well as special industries such as pharmaceuticals and environmental protection.

Description of drawings

Fig. 1 is the periodate, metaperiodate or iodate sterilization of 1.0% alkali metal, the production flow diagram of disinfection spray

Detailed ways

The following examples help to understand the content of the present invention, but are not limited to the present invention

Sterilization, disinfection spray main raw material

1) Chemical name: sodium periodate, sodium metaperiodate, sodium iodate, potassium periodate, potassium metaperiodate or potassium iodate

2) Glacial acetic acid

Chemical name: acetic acid

English name: Acetic acid

Molecular formula: _CH3COOH

Molecular weight: 60.05

Properties: Colorless clear liquid. Has a pungent odor. Melting point: 16.5°C. Soluble in water, ethanol and ether.

Manufacturer: Shanghai Reagent No. 1 Factory

3) pure water

Chemical name: deionized water

English name: Water

Molecular formula: _H2O

Molecular weight: 18

Properties: Odorless and tasteless liquid

Example 1 1.5% Sodium Metaperiodate Bactericidal and Disinfectant Spray Formula

Sodium metaperiodate or sodium periodate 1.5%

Glacial acetic acid 1.0%

Pure water 97.5%

     Example 2 0.5% bactericidal, disinfectant spray formula

Sodium metaperiodate or sodium periodate 0.5%

Pure water 99.5%

    Example 3 0.5% bactericidal, disinfectant spray formula

Potassium metaperiodate or potassium periodate 0.5%

Glacial acetic acid 1.0%

Pure water 98.5%

Example 4 Sterilization and disinfection sprayer formula for routine use at home

Recipe for routine household sterilization and disinfection spray: Add 1000mL of pure water to a 1500mL flask, add 5.0g of sodium periodate while stirring, and after all dissolve, it becomes 1000mL 0.5% household sterilization and disinfection spray. Direct spraying can kill pathogenic bacteria within 1 minute.

         Example 5 The formulation of bactericidal and disinfecting sprays used in polluted areas

Bactericidal and disinfectant spray formula used in polluted areas: Add 1000mL pure water to a 1500mL flask, add 15.0g sodium metaperiodate and 10g acetic acid while stirring, and after all dissolve, it becomes 1000mL 1.5% household sterilizing and disinfecting spray . Direct spraying can kill pathogenic bacteria within 1 minute.

Claims (11)

1. an iodate composition, which contains the following components: Periodate or metaperiodate of alkali metal 0.1-2.5% (by weight), Weak acid 0～1.0% (by weight), Pure water 96.5～99.9% (by weight), The said weak acid is C1-C6 organic carboxylic acid except citric acid. 2. iodate composition as claimed in claim 1, it contains following component: Periodate or metaperiodate of alkali metal 0.2～1.5% (by weight), Weak acid 0～1.0% (by weight), Pure water 97.5～99.8% (by weight), Described weak acid is acetic acid. 3. iodate composition as claimed in claim 1, it contains following component: Periodate or metaperiodate of alkali metal 0.2～1.5% (by weight), Pure water 98.5-99.8% (by weight). 4. iodate composition as claimed in claim 1, it contains following component: Periodate or metaperiodate of alkali metal 0.2～1.5% (by weight), Acetic acid 0.2～1.0% (by weight), Pure water 97.5-99.6% (by weight). 5. iodate composition as claimed in claim 1 is characterized in that the periodate or metaperiodate of described alkali metal is sodium periodate, sodium metaperiodate, periodic acid Potassium or potassium metaperiodate. 6. The iodate composition as claimed in claim 1, characterized in that the pH value of said composition is 2 to 6.5. 7. The iodate composition as claimed in claim 1, characterized in that said composition is diluted with water by 1 to 5 times for use. 8. iodate composition as claimed in claim 1 is characterized in that adding spices in the above-mentioned composition. 9. the purposes of iodate composition as claimed in claim 1 is characterized in that being used for environmental disinfection. 10. the purposes of iodate composition as claimed in claim 9 is characterized in that being used for sterilization, disinfection of public place and pharmacy, special industry of environmental protection. 11. the purposes of iodate composition as claimed in claim 9 is characterized in that being used for sterilization, disinfection aimed at killing atypical pneumonia bacteria.