CN1221426A - 来普亭(鄂毕肽)片段 - Google Patents
来普亭(鄂毕肽)片段 Download PDFInfo
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- CN1221426A CN1221426A CN97195311A CN97195311A CN1221426A CN 1221426 A CN1221426 A CN 1221426A CN 97195311 A CN97195311 A CN 97195311A CN 97195311 A CN97195311 A CN 97195311A CN 1221426 A CN1221426 A CN 1221426A
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- peptide
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- APSBXTVYXVQYAB-UHFFFAOYSA-M sodium docusate Chemical compound [Na+].CCCCC(CC)COC(=O)CC(S([O-])(=O)=O)C(=O)OCC(CC)CCCC APSBXTVYXVQYAB-UHFFFAOYSA-M 0.000 description 1
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- ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
- BYGOPQKDHGXNCD-UHFFFAOYSA-N tripotassium;iron(3+);hexacyanide Chemical compound [K+].[K+].[K+].[Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] BYGOPQKDHGXNCD-UHFFFAOYSA-N 0.000 description 1
- DCXPBOFGQPCWJY-UHFFFAOYSA-N trisodium;iron(3+);hexacyanide Chemical compound [Na+].[Na+].[Na+].[Fe+3].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] DCXPBOFGQPCWJY-UHFFFAOYSA-N 0.000 description 1
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- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Child & Adolescent Psychology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9611775.9A GB9611775D0 (en) | 1996-06-06 | 1996-06-06 | Novel compounds |
| GB9611775.9 | 1996-06-06 | ||
| GB9618540.0 | 1996-09-05 | ||
| GBGB9618540.0A GB9618540D0 (en) | 1996-09-05 | 1996-09-05 | Novel compounds |
| GB9703493.8 | 1997-02-20 | ||
| GBGB9703493.8A GB9703493D0 (en) | 1997-02-20 | 1997-02-20 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1221426A true CN1221426A (zh) | 1999-06-30 |
Family
ID=27268305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97195311A Pending CN1221426A (zh) | 1996-06-06 | 1997-06-04 | 来普亭(鄂毕肽)片段 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0912609A2 (cs) |
| JP (1) | JP2000512137A (cs) |
| KR (1) | KR20000016402A (cs) |
| CN (1) | CN1221426A (cs) |
| AR (1) | AR008765A1 (cs) |
| AU (1) | AU3337297A (cs) |
| BR (1) | BR9709529A (cs) |
| CA (1) | CA2257240A1 (cs) |
| CZ (1) | CZ397898A3 (cs) |
| IL (1) | IL127153A0 (cs) |
| NO (1) | NO985683D0 (cs) |
| NZ (1) | NZ332879A (cs) |
| PL (1) | PL330361A1 (cs) |
| TR (1) | TR199802534T2 (cs) |
| WO (1) | WO1997046585A2 (cs) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110183530A (zh) * | 2019-06-21 | 2019-08-30 | 深圳市亚辉龙生物科技股份有限公司 | 瘦素免疫原、杂交瘤细胞、单克隆抗体、多克隆抗体及应用 |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001968A (en) | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
| EP1101112B1 (en) | 1998-07-28 | 2004-10-06 | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. | Leptin-mediated gene-induction |
| US7208572B2 (en) | 1998-08-21 | 2007-04-24 | Albany Medical College | Leptin-related peptides |
| US6777388B1 (en) | 1998-08-21 | 2004-08-17 | Clf Medical Technology Acceleration Program, Inc. | Leptin-related peptides |
| US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
| CA2388417A1 (en) | 1999-09-22 | 2001-03-29 | Genset | Methods of screening for compounds that modulate the lsr-leptin interaction and their use in the prevention and treatment of obesity-related diseases |
| AU8178401A (en) | 2000-05-22 | 2001-12-03 | Vlaams Interuniv Inst Biotech | Receptor-based interaction trap |
| DK2219031T3 (da) | 2001-10-22 | 2013-06-17 | Amgen Inc | Anvendelse af leptin til behandling af human lipoatrofi og fremgangsmåde til bestemmelse af prædisposition for behandlinngen |
| ES2300817T3 (es) | 2003-09-08 | 2008-06-16 | Laboratoires Serono Sa | Tratamiento de enfermedades fibroticas. |
| IN2012DN03921A (cs) | 2004-02-11 | 2015-09-04 | Amylin Pharmaceuticals Inc | |
| US7575878B2 (en) | 2004-11-18 | 2009-08-18 | Vib Vzw | Methods of inhibiting leptin-induced signaling with fibronectin III domain antibodies |
| WO2007022123A2 (en) | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
| EA011653B1 (ru) | 2005-02-11 | 2009-04-28 | Амилин Фармасьютикалз, Инк. | Аналоги и гибридные полипептиды gip с избираемыми свойствами |
| US7629315B2 (en) | 2005-03-09 | 2009-12-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Compositions for blocking the inhibitory effect of human CRP on human leptin |
| EP2330125A3 (en) | 2005-08-11 | 2012-12-12 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
| ES2319048B1 (es) * | 2007-06-20 | 2010-02-10 | Universitat De Les Illes Balears | Uso de leptina en el tratamiento de alteraciones en los habitos alimentarios. |
| US8889622B2 (en) | 2007-07-25 | 2014-11-18 | Washington University | Methods of inhibiting seizure in a subject |
| GB2451858A (en) * | 2007-08-15 | 2009-02-18 | Sergiy Konovchuk | Methods of reducing body fat and treating obesity |
| EP2229362A1 (en) | 2007-12-05 | 2010-09-22 | AstraZeneca AB | Piperazines as anti-obesity agents |
| CA2707248A1 (en) | 2007-12-05 | 2009-06-11 | Astrazeneca Ab | New compounds ii |
| CA2726441A1 (en) * | 2008-06-04 | 2009-12-10 | Michael Higginbottom | New pyridine derivatives as leptin receptor modulator mimetics |
| WO2009147211A1 (en) * | 2008-06-04 | 2009-12-10 | Biovitrum Ab (Publ) | New compounds v |
| WO2010118384A2 (en) | 2009-04-10 | 2010-10-14 | Amylin Pharmaceuticals, Inc. | Amylin agonist compounds for estrogen-deficient mammals |
| EP2569326B1 (en) * | 2010-05-11 | 2016-08-10 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Peptide-based inhibitor of interleukin-10 or stat-3 activation |
| CA3138758A1 (en) | 2010-09-28 | 2012-04-19 | Amylin Pharmaceuticals, Llc | Highly soluble leptins |
| CN104829707B (zh) * | 2015-05-06 | 2017-12-19 | 广东省生物资源应用研究所 | 一条cd环和e螺旋区突变的瘦素活性肽及其编码基因和应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US5552523A (en) * | 1995-01-31 | 1996-09-03 | Eli Lilly And Company | Anti-obesity proteins |
| JPH11501297A (ja) * | 1995-01-31 | 1999-02-02 | イーライ・リリー・アンド・カンパニー | 抗肥満症タンパク質 |
| AU4766596A (en) * | 1995-01-31 | 1996-08-21 | Eli Lilly And Company | Ob gene product antibodies |
| WO1996031526A1 (en) * | 1995-04-06 | 1996-10-10 | Amylin Pharmaceuticals, Inc. | Anti-obesity agents |
| GB9509164D0 (en) * | 1995-05-05 | 1995-06-28 | Smithkline Beecham Plc | Novel compounds |
-
1997
- 1997-06-04 TR TR1998/02534T patent/TR199802534T2/xx unknown
- 1997-06-04 CN CN97195311A patent/CN1221426A/zh active Pending
- 1997-06-04 WO PCT/EP1997/002968 patent/WO1997046585A2/en not_active Application Discontinuation
- 1997-06-04 CA CA002257240A patent/CA2257240A1/en not_active Abandoned
- 1997-06-04 AR ARP970102432A patent/AR008765A1/es unknown
- 1997-06-04 IL IL12715397A patent/IL127153A0/xx unknown
- 1997-06-04 CZ CZ983978A patent/CZ397898A3/cs unknown
- 1997-06-04 EP EP97929156A patent/EP0912609A2/en not_active Withdrawn
- 1997-06-04 KR KR1019980709976A patent/KR20000016402A/ko not_active Application Discontinuation
- 1997-06-04 NZ NZ332879A patent/NZ332879A/xx not_active IP Right Cessation
- 1997-06-04 JP JP10500240A patent/JP2000512137A/ja active Pending
- 1997-06-04 PL PL97330361A patent/PL330361A1/xx unknown
- 1997-06-04 AU AU33372/97A patent/AU3337297A/en not_active Abandoned
- 1997-06-04 BR BR9709529A patent/BR9709529A/pt not_active Application Discontinuation
-
1998
- 1998-12-04 NO NO985683A patent/NO985683D0/no not_active Application Discontinuation
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110183530A (zh) * | 2019-06-21 | 2019-08-30 | 深圳市亚辉龙生物科技股份有限公司 | 瘦素免疫原、杂交瘤细胞、单克隆抗体、多克隆抗体及应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CZ397898A3 (cs) | 1999-04-14 |
| CA2257240A1 (en) | 1997-12-11 |
| NZ332879A (en) | 2000-09-29 |
| WO1997046585A2 (en) | 1997-12-11 |
| NO985683L (no) | 1998-12-04 |
| IL127153A0 (en) | 1999-09-22 |
| PL330361A1 (en) | 1999-05-10 |
| JP2000512137A (ja) | 2000-09-19 |
| WO1997046585A3 (en) | 1998-04-23 |
| TR199802534T2 (xx) | 1999-03-22 |
| BR9709529A (pt) | 1999-08-10 |
| EP0912609A2 (en) | 1999-05-06 |
| AR008765A1 (es) | 2000-02-23 |
| NO985683D0 (no) | 1998-12-04 |
| AU3337297A (en) | 1998-01-05 |
| KR20000016402A (ko) | 2000-03-25 |
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