CN118575823A - A kind of insecticide composition and application - Google Patents

Abstract

The invention relates to a pesticide composition and an application method thereof, wherein the composition comprises A, B two active components, and a component A is selected from benzamide compounds shown in a general formula I:

Description

A kind of insecticide composition and application

Technical Field

The invention belongs to the field of pesticides, and specifically relates to a pesticide composition and application thereof.

Background Art

Chinese invention patent CN201910373870.6 discloses a benzamide compound, which has excellent insecticidal activity and can effectively control pests such as diamondback moth, armyworm, and striped stem borer at a lower dose. This type of compound has the characteristics of high insecticidal efficiency and rapid onset. It can achieve high insecticidal activity after one day of application and can achieve extremely high insecticidal effect within three days, showing broad application prospects.

Pyrethroids and pyrethrins are a class of broad-spectrum insecticides that can control a variety of pests. They can disrupt the normal physiological state of insect nerves, causing them to die from excitement, spasms to paralysis, and have a strong contact killing effect on insects. Some varieties also have stomach poison or fumigation effects. This type of agent has the advantages of small dosage, low concentration, relatively safe for humans and animals, and little pollution to the environment.

Actual agricultural experience and a large amount of scientific research data show that long-term, repeated and exclusive application of a single active compound to control pests will in many cases lead to the emergence of pest resistance, resulting in a significant reduction in the control effect of the active compound, or even a complete loss. By mixing two active ingredient pesticides into a mixed component in a certain proportion, the control effect can often be improved, the amount of active ingredients can be reduced, costs can be saved, and the development of pest resistance can be delayed.

Summary of the invention

In order to reduce the risk of pests developing resistance to active compounds and also to improve the control effect on pests, the present invention aims to provide a pesticide composition and its application.

To achieve the above object, the technical solution of the present invention is as follows:

A pesticide composition, the composition comprises component A and component B; the weight ratio between the two components A and B is 1:100 to 100:1; wherein component A is a benzamide compound represented by general formula I; component B is a pyrethroid or pyrethrin insecticide, including bifenthrin, high-efficiency cyhalothrin, high-efficiency cyhalothrin, deltamethrin, high-efficiency cypermethrin, cis-cypermethrin, cypermethrin, permethrin, allethrin, tetramethrin, methothrin, cypermethrin, cyfluthrin, cypermethrin, cypermethrin, pyrethrin;

The benzamide compound represented by the general formula I, wherein:

R1 is selected from halogen;

R2 is selected from halogen or trifluoromethyl;

R3 is selected from heptafluoroisopropyl or nonafluoro-2-butyl;

R4 and R5 are each independently selected from hydrogen, methyl, ethyl or cyanomethyl; and at least one of R4 and R5 is selected from cyanomethyl;

R6 is selected from hydrogen, fluorine, chlorine, bromine, cyano, nitro, methyl, ethyl, propyl, tert-butyl, trifluoromethyl, heptafluoroisopropyl, methoxy or trifluoromethoxy; n=1, 2 or 3;

X1 is selected from fluorine;

X2, X3, and X4 are each independently selected from hydrogen or fluorine.

Preferably, component A in the composition is a benzamide compound represented by the general formula I: In the general formula I, R3 is selected from heptafluoroisopropyl;

The B component is selected from the group consisting of bifenthrin, high-efficiency cyhalothrin, high-efficiency cyhalothrin, deltamethrin, high-efficiency cypermethrin, cis-cypermethrin, cypermethrin, permethrin, allethrin, tetramethrin, methothrin, cypermethrin, and cyhalothrin;

Among them, the weight ratio between components A and B is 1:90 to 90:1.

More preferably, the weight ratio between the two components A and B is 1:75 to 75:1; wherein the component A is a benzamide compound selected from the following table represented by the general formula I:

The B component is selected from the group consisting of: bifenthrin, high-efficiency cyhalothrin, high-efficiency cyfluthrin, deltamethrin, high-efficiency cypermethrin, cis-cypermethrin, cypermethrin, permethrin, allethrin, and tetramethrin.

Further preferably, the weight ratio between the two components A and B is 1:50 to 50:1; wherein the component A is a benzamide compound selected from the following table represented by the general formula I:

The B component is selected from the group consisting of: bifenthrin, high-efficiency cyhalothrin, high-efficiency cyfluthrin, deltamethrin, high-efficiency cypermethrin, cis-cypermethrin, cypermethrin, and permethrin.

More preferably, the weight ratio between the two components A and B is 1:20 to 20:1; wherein the component A is a benzamide compound selected from the following table represented by the general formula I:

The B component is selected from the group consisting of bifenthrin, high-efficiency cyhalothrin, high-efficiency cyfluthrin, deltamethrin, high-efficiency cypermethrin, and cis-cypermethrin.

A pesticide composition is formulated as a directly sprayable solution, powder, suspension, highly concentrated aqueous, oily or other suspension, dispersion, emulsion, oil dispersion, paste, dust, mixture for broadcasting or granules, and can be applied by spraying, atomizing, dusting, broadcasting, smearing, or pouring, etc., for controlling agricultural and forestry pests or urban health pests. The application form depends on the specific purpose; in each case, it should be ensured that the composition of the present invention is finely and evenly distributed.

The composition of the present invention can be provided in the form of a finished formulation. Therefore, the present invention also includes an insecticide composition in the form of a formulation. The formulation of the composition of the present invention can be prepared by known methods and made into emulsifiable concentrates, suspensions, water-dispersible granules, aqueous emulsions, microemulsions, soluble liquids, wettable powders or oil suspensions as required. The cumulative content of the active ingredient in the composition is between 0.5% and 95%, and the preferred cumulative content is between 1% and 85%. The content of the active ingredient in the composition depends on the application amount when used alone, and also depends on the mixing ratio and the degree of synergistic effect. The optimal range of the active ingredient content varies depending on the formulation type of the composition.

The preparation of the finished preparation of the composition of the present invention can be prepared by a common processing method, that is, after mixing the active substance with a liquid carrier (solvent) or a solid carrier, one or more surfactants such as an emulsifier, a dispersant, a wetting agent, a binder, a stabilizer and a defoamer are added. Usually, the composition contains at least one carrier and at least one surfactant. In each case, it should be ensured that the active component of the composition of the present invention is evenly distributed.

Suspension concentrates usually require sand milling to obtain stable non-sedimentation flowable products. Suspension concentrates usually contain 5-75% active ingredients, 5-15% dispersants, 0.1-10% thixotropic agents, 4-10% antifreeze agents, 0-10% other additives such as defoamers, preservatives, stabilizers, penetrants and thickeners, and the balance of liquid carriers.

Water-dispersible granules are usually made into 10-100 international standard mesh (1.676-0.152 mm) granules, which can be prepared by extrusion, impregnation or spray granulation. Usually water-dispersible granules contain 0.5-75% of active ingredients and 5-20% of surfactants such as stabilizers, wetting and dispersing agents, disintegrants and binders, and the balance of inert carriers.

Water emulsion is to mix the original drug, organic solvent and surfactant to form an oil phase; mix water and antifreeze together to form a uniform and transparent water phase. Use a high shear emulsifier to shear the oil phase at high speed, and slowly add the water phase to the oil phase. Usually, the active ingredient is 1-60%, the surfactant is 5-20%, the antifreeze is 2-10%, and the balance is water.

Emulsifiable concentrates usually contain 10-50% of active ingredients, 2-20% of emulsifiers, 0-20% of other additives such as stabilizers, penetrants, corrosion inhibitors, etc., and solvents (and co-solvents if necessary).

Microemulsion is a mixture of the original drug, organic solvent, surfactant and water to form a uniform transparent aqueous phase. Usually, the active ingredient is 1-50%, the surfactant is 10-40%, the antifreeze is 2-10%, and the balance is water.

Soluble liquid preparations are made by mixing active ingredients, organic solvents, and surfactants together to form a uniform transparent liquid, usually 1-50% active ingredient, 6-20% surfactant, and the balance organic solvent.

Oil suspension is made by adding active ingredients, surfactants, and oil-based carriers into a sand mill and grinding until the particle size is qualified, usually 2-60% active ingredients, 6-20% surfactants, and the balance oil-based carrier.

Wettable powders usually contain 10 to 85% of active ingredients. In addition to a solid inert carrier, they usually contain 3 to 10% of a dispersant and may also contain 0 to 10% of a stabilizer and/or other additives, such as a penetrant or a sticker.

Aqueous dispersions and emulsions (e.g. compositions obtained by diluting the emulsifiable concentrates, wettable powders or concentrates of the invention with water) are also within the scope of the invention. The emulsions may be of the water-in-oil type or the oil-in-water type and may have a thick, paste-like consistency.

The finished preparation of the composition of the present invention uses a variety of commercial carriers and various auxiliary agents, for example, including but not limited to the following substances.

Suitable liquid carriers or solvents can be water, various aromatic hydrocarbons, aliphatic hydrocarbons, ketones, ethers, etc., such as one or more of toluene, xylene, acetone, cyclohexanone, benzene, cyclohexane, isopropanol, ethylene glycol, sorbitol, methanol, ethanol, butanol, dimethylformamide, decalin, motor oil, petroleum ether, etc.

Suitable solid carriers include natural or synthetic clays and silicates, solid carriers suitable for dusts include naturally occurring rock powders, chalk, quartz, clay, montmorillonite, silicon dioxide, diatomaceous earth, pumice, gypsum, talc, bentonite, kaolin, clay and synthetic ground minerals (such as finely dispersed silicic acid or alumina). Suitable granular carriers include crushed and graded natural rocks such as calcite, marble, pumice, sepiolite and dolomite and synthetic granules made from organic and inorganic powders.

Suitable co-solvents are one or more of methanol, phenol, isoamyl alcohol, dimethyl sulfoxide, ethyl acetate, butanone, dimethylformamide and the like.

Suitable emulsifiers may be polyoxyethylene (n20) phenethyl phenol ether oleate, ethoxylated castor oil, alkyl aromatic polyoxyethylene polyoxypropylene ether, alkyl aromatic formaldehyde resin polyoxyethylene ether, Nongru 0201B, Nongru 0203B, Nongru T-20, Nongru 36#, Nongru S-80, Nongru 100#, concentrated milk 500#, Nongru 507#, Nongru 600#, Nongru 1601#, Nongru 2201#, etc.

Suitable dispersants can be sodium lignin sulfonate, calcium lignin sulfonate, methylnaphthalene sulfonic acid formaldehyde condensate, methylnaphthalene sulfonate sodium formaldehyde condensate, sodium methylenenaphthalene sulfonate, sodium oleic acid methylaminoethyl sulfonate, epoxy polyether, p-tert-butyl ether, piperonyl butoxide, alkylamide taurate, dibutylnaphthalene sulfonic acid formaldehyde condensate, alkylphenol polyoxyethylene phosphate, methylcellulose, etc.

Suitable wetting agents may be sodium sulfate, sodium lauryl sulfate, sodium methylene naphthalene sulfonate, sodium dodecylbenzene sulfonate, calcium dodecylbenzene sulfonate, sodium alkylnaphthalene sulfonate, fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, and the like.

Suitable thickeners can be synthetic (such as carbonyl methyl alcohol, polyvinyl alcohol, polyvinyl acetate) or natural water-soluble polymers (such as xanthan gum, gelatin, gum arabic, polyvinyl pyrrolidone, magnesium aluminum silicate, polyvinyl alcohol, polyethylene glycol, phenolic resin, shellac, carboxymethyl cellulose and sodium alginate, etc.), added to the preparation in the form of powder, granules or latex.

Suitable defoamers are foaming agents, silicones, C8-10 fatty alcohols, phosphates, C10-20 saturated fatty acids (such as capric acid) and amides.

Suitable oxidants are: potassium chlorate, sodium chlorate, potassium perchlorate, sodium nitrate, potassium nitrate, potassium permanganate, etc.

Suitable binders may be polyvinyl alcohol, polyvinyl acetate, xanthan gum, gelatin, carboxymethyl cellulose, sodium alginate and the like.

The composition of the present invention is suitable for preventing and treating a variety of important agricultural and forestry pests and urban health pests, such as armyworms, beet armyworms, cotton bollworms, cutworms, cabbage armyworms, apple leaf rollers, rice leaf rollers, corn borers, striped stem borers, diamondback moths, cabbage worms, American white moths, tent caterpillars, gypsy moths, East Asian migratory locusts, underground pests, leafminers, leafminers, aphids, mites, etc., urban pests such as termites, cockroaches, ants, flies, mosquitoes, etc. It can be used for fruit trees such as apples, pears, citrus, litchi, etc., cereals such as wheat, rice, etc., beans such as soybeans, kidney beans, etc., cotton, vegetables such as cabbage, cauliflower, cabbage, rape, tomatoes, peppers, etc., and flowers. When used to prevent and treat urban pests, it can be used in homes, various public places, offices, and trees and dams where termites harm. Therefore, the present invention also includes the use of the composition of the present invention to control agricultural and forestry pests or urban health pests. The more suitable effective dose usually selected is 1 gram to 1000 grams per hectare, and the preferred effective dose is 5 grams to 500 grams per hectare.

The advantages of the present invention are as follows: the insecticide composition of the present invention has a very obvious synergistic effect, and the control effect on pests is significantly improved; the composition reduces the dosage of the compound during application, thereby reducing the use cost and reducing environmental pollution; the present invention combines compounds with different action mechanisms and chemical structure types, and there is no problem of cross-resistance. Using it to control pests can delay the occurrence of pest resistance and improve the control effect of resistant populations.

DETAILED DESCRIPTION

The insecticide composition of the present invention can be illustrated by the following examples, but the present invention is by no means limited thereto. The percentage or proportion of each component in the examples is by weight. The active component in each formula is calculated as the effective content.

Preparation formula example

Example 1, 20% Bifenthrin·Compound (2.17) Suspension

15 parts of cypermethrin, 5 parts of compound (2.17), 3 parts of Nong Ru 1601, 6 parts of Nong Ru 0201B, 0.3 parts of xanthan gum, 0.5 parts of white carbon black, 5 parts of ethylene glycol, and water to make up to 100% are added to a sand mill and ground to prepare a 20% cypermethrin·compound (2.17) suspension.

Example 2, 15% highly effective cyhalothrin·compound (3.321) suspension

5 parts of highly effective chlorfenapyr, 10 parts of compound (3.321), 3 parts of sodium lignin sulfonate, 5 parts of sodium naphthalenesulfonate formaldehyde condensate, 2 parts of Nong Ru 1601, 3 parts of Nong Ru 0201B, 0.1 parts of xanthan gum, 0.2 parts of white carbon black, 5 parts of ethylene glycol and a small amount of defoaming agent were added to a sand mill and ground into a fine powder to prepare a 15% highly effective chlorfenapyr·compound (3.321) suspension.

Example 3, 20% highly effective cyfluthrin·compound (30.321) suspension

5 parts of highly effective flucythrin, 15 parts of compound (30.321), 1 part of Nong Ru S-80, 2 parts of Nong Ru 600#, 5 parts of Nong Ru 0203B, 4 parts of sodium lignin sulfonate, 3 parts of sodium dibutylnaphthalene sulfonate formaldehyde condensate, 0.5 parts of xanthan gum, 0.8 parts of white carbon black, 5 parts of ethylene glycol, and water to make up to 100% are added into a sand mill and ground to prepare a 20% highly effective flucythrin·compound (30.321) suspension.

Example 4: 12% Deltamethrin·Compound (9.7) Suspension

Add 6 parts of cypermethrin, 6 parts of compound (9.7), 3 parts of sodium naphthalenesulfonate formaldehyde condensate, 5 parts of sodium methylnaphthalenesulfonate formaldehyde condensate, 3 parts of Nong Ru NP-7, 3 parts of Nong Ru 0201B, 3 parts of triethyl phosphate, 5 parts of ethylene glycol, and make up to 100% with water, add them into a sand mill, grind them into a fine powder, and prepare a 12% cypermethrin·compound (9.7) suspension.

Example 5: 8% highly effective cypermethrin·compound (2.7) aqueous emulsion

4 parts of highly effective cypermethrin, 4 parts of compound (2.7), 0.8 parts of polyvinyl alcohol, 9 parts of alkylaryl polyoxyethylene polyoxypropylene ether, 16 parts of Nong Ru 2201, 11 parts of dimethylformamide and 5 parts of ethylene glycol are dissolved into a uniform oil phase. Under high-speed stirring, the remaining water is added to the oil phase to make up to 100% to form an 8% highly effective cypermethrin·compound (2.7) aqueous emulsion.

Example 6: 5% cis-cypermethrin·compound (2.321) aqueous emulsion

4 parts of cis-cypermethrin, 1 part of compound (2.321), 8 parts of polyoxyethylene (n20) phenethylphenol ether oleate, 3 parts of calcium dodecylbenzenesulfonate, 2 parts of agricultural milk 507#, 5 parts of cyclohexanone, 3 parts of xylene and 1 part of decasorbitol are added together and dissolved into a uniform oil phase. Under high-speed stirring, the remaining water is added to the oil phase to make up to 100%, thereby forming a 5% cis-cypermethrin·compound (2.321) aqueous emulsion.

Example 7: 10% highly effective cyhalothrin·compound (2.43) microemulsion

2 parts of highly effective chlorfenapyr, 8 parts of compound (2.43), 10 parts of diphenylphenol polyoxyethylene (n18) ether formaldehyde condensate, 10 parts of Nong Ru 2201, 5 parts of Nong Ru 600#, 10 parts of ethyl acetate and 15 parts of cyclohexanone are added together and dissolved into a uniform oil phase. The remainder is made up to 100% with water. Under high-speed stirring, the aqueous phase is added to the oil phase or the oil phase is added to the aqueous phase to form a 10% highly effective chlorfenapyr·compound (2.43) microemulsion.

Example 8, 12% Deltamethrin·Compound (7.321) Soluble Solution

Mix 8 parts of cypermethrin, 4 parts of compound (7.321), 15 parts of Nong Ru 507#, 5 parts of Nong Ru 1601, 6 parts of Nong Ru 100#, 12 parts of dimethylformamide, 10 parts of methanol, 20 parts of dimethyl sulfoxide, and methyl cellulose to make up the balance, mix well, and heat in a hot water bath to dissolve if necessary to prepare a 12% cypermethrin·compound (7.321) soluble solution.

Example 9, 25% Bifenthrin·Compound (17.321) Oil Suspension

Add 15 parts of cypermethrin, 10 parts of compound (17.321), 6 parts of Nong Ru 0201B, 2 parts of Nong Ru 700#, 5 parts of Nong Ru S-80, 10 parts of methyl oleate, 3 parts of white carbon black, 1 part of Nong Ru T-20, and make up the balance to 100% with methylated soybean oil, add them into a sand mill, grind them into powder, and prepare a 25% cypermethrin·compound (17.321) oil suspension.

Example 10, 15% cis-cypermethrin·compound (8.321) emulsifiable concentrate

Add 10 parts of cis-cypermethrin, 5 parts of compound (8.321), 7 parts of Nong Ru 0201B, 3 parts of Nong Ru NP-15, 2 parts of Nong Ru 700, 10 parts of dimethylformamide and xylene to make up to 100%, mix well, and form 15% cis-cypermethrin·compound (8.321) emulsifiable concentrate.

Example 11: 60% highly effective cypermethrin·compound (11.7) water dispersible granules

30 parts of highly effective cypermethrin, 30 parts of compound (11.7), 6 parts of sodium methylenenaphthalenesulfonate, 5 parts of naphtholsulfonic acid formaldehyde condensate, 5 parts of epoxy polyether, 5 parts of soluble starch, 5 parts of sodium sulfate, and bentonite to 100%, mixed and crushed, and then kneaded with water, and then added to a granulator equipped with a screen of a certain specification for granulation. Then, it was dried and sieved (according to the range of the screen) to obtain 60% highly effective cypermethrin·compound (11.7) water-dispersible granules.

Example 12: 50% highly effective cyhalothrin·compound (21.321) water dispersible granules

10 parts of highly effective cyhalothrin, 40 parts of compound (21.321), 12 parts of sodium methylnaphthalene sulfonate formaldehyde condensate, 5 parts of epoxy polyether, 15 parts of soluble starch, gypsum to 100%, mixed and crushed, then kneaded with water, and added into a granulator equipped with a screen of a certain specification for granulation. Then, dried and sieved (according to the range of the screen) to obtain 50% highly effective cyhalothrin·compound (21.321) water-dispersible granules.

Example 13, 25% Bifenthrin·Compound (58.321) Wettable Powder

5 parts of bifenthrin, 20 parts of compound (58.321), 2 parts of sodium dodecyl sulfate, 6 parts of sodium salt of naphthol sulfonate formaldehyde condensate, 4 parts of sodium lignin sulfonate, 5 parts of white carbon black, bentonite, etc. are added to 100%, fully mixed, and crushed with an ultrafine grinder to obtain a 25% bifenthrin·compound (58.321) wettable powder.

Example 14, 20% highly effective cyhalothrin·compound (2.43) wettable powder

10 parts of highly effective chlorfenapyr, 10 parts of compound (2.43), 2 parts of sodium dodecyl sulfate, 6 parts of sodium salt of cresol sulfonate formaldehyde condensate, 4 parts of sodium lignin sulfonate, 3 parts of p-tert-butyl ether, 2 parts of detergent LS, 5 parts of white carbon black, and light calcium carbonate to make up the balance are fully mixed and pulverized with an ultrafine grinder to obtain a 20% highly effective chlorfenapyr·compound (2.43) wettable powder.

Example 15: 30% Deltamethrin·Compound (9.7) Wettable Powder

15 parts of deltamethrin, 15 parts of compound (9.7), 2 parts of sodium lauryl sulfate, 1 part of carboxymethyl cellulose, 10 parts of sodium lignin sulfonate, and light calcium carbonate are added to make up to 100%, mixed thoroughly, and crushed with an ultrafine grinder to obtain a 30% deltamethrin·compound (9.7) wettable powder.

Biological Activity Assay Example

The active compounds, alone or in combination, were prepared as stock solutions in acetone or DMSO containing 0.25% by weight of the active compounds. 1% by weight of an emulsifier EL (wetting agent based on ethoxylated alkylphenols with emulsifying and dispersing action) was added to the stock solution, and the active compound or mixture was diluted with water to the desired concentration in the following examples.

In the indoor biological activity assay example, the efficacy is used to measure the control effect of the active compound on pests. The specific meaning of efficacy is: the mortality rate of pests caused by the test concentration of the compound.

The expected efficacy of the active compound mixture was determined using Colby's formula [S.R.Colby. Calculating Synergistic and Antagonistic Responses of Herbicide Combinations. Weeds, 1967, 15(1):20-22] and compared with the observed efficacy.

Colby formula: E = x + y - xy / 100

E: expected efficacy when using a mixture of active compounds A and B in the concentrations a and b, respectively, expressed as % of the untreated control.

x the efficacy of active compound A at concentration a, expressed as % of the untreated control;

y Efficacy of active compound B at concentration b, expressed as % of the untreated control.

If the actual observed efficacy (O) is greater than the expected efficacy (E), then the effect of the combination is a synergistic effect, and in mathematical terms, the synergistic effect corresponds to a positive difference in (O-E). If the actual observed efficacy (O) is equal to the expected efficacy (E), then the effect of the combination is a simple additive effect, and no synergistic effect is shown. In mathematical terms, the difference corresponding to (O-E) is zero. If the actual observed efficacy (O) is less than the expected efficacy (E), then the effect of the combination is an antagonistic effect, and in mathematical terms, the difference corresponding to (O-E) is a negative value.

Example 16: Determination of synergistic effect on Plutella xylostella

The treatment was carried out by the dipping method. A hole puncher was used to make a 2cm diameter leaf disc from the cabbage leaves. The leaf disc was dipped in the liquid for 5s, taken out and dried in the shade, and placed in a 9cm culture dish lined with filter paper. The 2nd instar larvae of the diamondback moth (Plutellaxylostella) were selected and placed in the culture dish. Each treatment was repeated 4 times. The treated test insects were placed in an observation room at a temperature of 24-26°C, a humidity of RH 60%, and a light intensity of L:D=14:10. The reaction of the test insects was observed regularly. After 48h, the number of dead and alive insects was investigated, and the efficacy of the active compound (mortality rate, the same below) was calculated.

The data results of each single active component and the composition of the present invention for controlling the 2nd instar larvae of Plutella xylostella are shown in Tables 1 and 2. The results show that the observed efficacy values of the composition of the present invention are all greater than the calculated efficacy values, indicating that the composition exhibits a synergistic effect within the test ratio range.

Table 1 Activity of individual active ingredients

Table 2 Activity of the composition of the present invention

Example 17: Determination of synergistic effect on Chilo suppressalis

The artificial feed culture plate method is adopted. A standard clean 24-well culture plate is selected. 1 mL of artificial feed is added to each well. After cooling and solidification, 0.05 mL of liquid medicine is added to each well of the culture plate using a continuous sampler, and then placed in a cool place to dry naturally. The 2nd instar larvae of the Chilo suppressalis are selected and inoculated into the culture plate, one larvae per well, and each treatment is repeated 4 times. The treated test insects are placed in an observation room at a temperature of 25-27°C, a humidity of RH 60%, and a light intensity of L:D=14:10. The reaction of the test insects is observed regularly, and the number of dead and alive insects is investigated after 72 hours. The calculation and evaluation method is the same as in Example 16.

The data results of each single active component and the composition of the present invention for controlling the second-instar larvae of Chilo suppressalis are shown in Tables 3 and 4. The results show that the observed efficacy values of the composition of the present invention are all greater than the calculated efficacy values, indicating that the composition exhibits a synergistic effect within the test ratio range.

Table 3 Activity of individual active ingredients

Table 4 Activity of the composition of the present invention

Example 18: Determination of synergistic effect on corn borer

The artificial feed culture plate method is adopted. A standard clean 24-well culture plate is selected. 1 mL of artificial feed is added to each well. After cooling and solidification, 0.05 mL of liquid medicine is added to each well of the culture plate using a continuous sampler, and then placed in a cool place to dry naturally. The 3rd instar larvae of corn borer (Ostrinia furnacalis) are selected and inoculated into the culture plate, one larvae per well, and each treatment is repeated 4 times. The treated test insects are placed in an observation room at a temperature of 23-25°C, a humidity of RH 60%, and a light intensity of L:D=14:10. The reaction of the test insects is observed regularly, and the number of dead and alive insects is investigated after 72 hours. The calculation and evaluation method is the same as in Example 16.

The data results of each single active component and the composition of the present invention for controlling the 3rd instar larvae of corn borer are shown in Tables 5 and 6. The results show that the observed efficacy values of the composition of the present invention are all greater than the calculated efficacy values, indicating that the composition exhibits a synergistic effect within the test ratio range.

Table 5 Activity of individual active ingredients

Table 6 Activity of the composition of the present invention

Example 19: Determination of synergistic effect on armyworms

The test adopts the dipping method. The corn leaves grown in the greenhouse are taken back and made into leaves with a length of 3 cm. The leaves are dipped in the liquid for 5 seconds, taken out and dried in the shade, and placed in a 9 cm culture dish padded with filter paper. The 3rd instar larvae of Mythimnaseperata are selected and placed in the culture dish. Each treatment is repeated 4 times. The treated test insects are placed in an observation room with a temperature of 24-26°C, a humidity of RH 60%, and a light intensity of L:D=14:10. The reaction of the test insects is observed regularly, and the number of dead and alive insects is investigated after 48 hours. The calculation and evaluation method is the same as in Example 16.

The data results of each single active component and the composition of the present invention for controlling the 3rd instar larvae of armyworm are shown in Tables 7 and 8. The results show that the observed efficacy values of the composition of the present invention are all greater than the calculated efficacy values, indicating that the composition exhibits a synergistic effect within the test ratio range.

Table 7 Activity of individual active ingredients

Table 8 Activity of the composition of the present invention

Claims (9)

1. An insecticide composition characterized in that: the composition comprises a component A and a component B; the weight ratio of the A, B components is 1:100-100:1; wherein the component A is a benzamide compound shown in the general formula I: r1 is selected from halogen; r2 is selected from halogen or trifluoromethyl; r3 is selected from heptafluoroisopropyl or nonafluoro-2-butyl; r4, R5 are each independently selected from hydrogen, methyl, ethyl or cyanomethyl; and at least one of R4 and R5 is selected from cyanomethyl; r6 is selected from hydrogen, fluorine, chlorine, bromine, cyano, nitro, methyl, ethyl, propyl, tert-butyl, trifluoromethyl, heptafluoroisopropyl, methoxy or trifluoromethoxy; n=1, 2 or 3; x1 is selected from fluorine; x2, X3, X4 are each independently selected from hydrogen or fluorine; the component B is pyrethroid or pyrethrin insecticide, comprises bifenthrin, high-efficiency cyhalothrin deltamethrin, beta-cypermethrin, alpha-cypermethrin, fenpropathrin deltamethrin, beta-cypermethrin Cyanothrin, fenpropathrin;

2. The insecticidal composition according to claim 1 wherein: the component A in the composition is a benzamide compound shown in the general formula I: r3 in the general formula I is selected from heptafluoroisopropyl;

The component B is selected from the following components: bifenthrin, lambda-cyhalothrin high-efficiency cyhalothrin deltamethrin, beta-cypermethrin, cis-cypermethrin fenpropathrin, permethrin, fenpropathrin allethrin, tetramethrin, and methyl ether pyrethrin, fenvalerate, cyhalothrin; wherein, the weight ratio of A, B to the two components is 1: 90-90: 1.

3. The insecticidal composition according to claim 2 wherein: the weight ratio of A, B to the two components is 1: 75-75: 1, a step of; wherein the a component is a compound selected from the following table:

The component B is selected from the following components: bifenthrin, lambda-cyhalothrin high-efficiency cyhalothrin high-efficiency fluorine chlorine cyanothrin (fenvalerate) cis-cypermethrin fenpropathrin, alpha-fenpropathrin permethrin, allethrin, tetramethrin.

4. A pesticidal composition according to claim 3, wherein: the weight ratio of A, B to the two components is 1: 50-50: 1, a step of; wherein the a component is a compound selected from the following table:

The component B is selected from the following components: bifenthrin high-efficiency cyhalothrin high-efficiency cyhalothrin, deltamethrin, fenpropathrin beta-cypermethrin, alpha-cypermethrin, fenpropathrin and permethrin.

5. The insecticidal composition according to claim 4 wherein: the weight ratio of A, B to the two components is 1: 20-20: 1, a step of; wherein the a component is a compound selected from the following table:

The component B is selected from the following components: bifenthrin high-efficiency cyhalothrin high-efficiency cyhalothrin deltamethrin, beta-cypermethrin and cis-cypermethrin.

6. The insecticidal composition of claim 1, wherein: can be prepared into emulsifiable concentrates, suspending agents, water dispersible granules, aqueous emulsion, microemulsion, soluble liquid agents, wettable powder or oil suspending agents according to the requirements.

7. The insecticidal composition of claim 6, wherein: the cumulative content of active ingredient in the pesticide composition is between 0.5% and 95%.

8. Use of a pesticide composition as defined in claim 7, wherein: the use of the pesticidal composition for controlling agroforestry pests or urban hygiene pests.

9. Use of a pesticide composition as claimed in any one of claims 6 to 8, wherein: the pesticide composition is applied to pests or a medium on which the pests grow in a spray, atomization, powdering, broadcasting, smearing, pouring and other modes.