CN118477132B

CN118477132B - Traditional Chinese medicine composition for treating allergic rhinitis

Info

Publication number: CN118477132B
Application number: CN202410946754.XA
Authority: CN
Inventors: 黎红; 周蓝飞; 刘玉红
Original assignee: Fuzhou Traditional Chinese Medicine Hospital Affiliated Hospital Of Jiangxi University Of Traditional Chinese Medicine; Jiangxi Harworld Biotechnology Co ltd
Current assignee: Fuzhou Traditional Chinese Medicine Hospital Affiliated Hospital Of Jiangxi University Of Traditional Chinese Medicine; Jiangxi Harworld Biotechnology Co ltd
Priority date: 2024-07-16
Filing date: 2024-07-16
Publication date: 2024-09-27
Anticipated expiration: 2044-07-16
Also published as: CN118477132A

Abstract

The invention relates to the technical field of traditional Chinese medicine compositions, and in particular discloses a traditional Chinese medicine composition for treating allergic rhinitis, which comprises the following raw material medicines in parts by weight: 8-12 parts of prepared aconite root, 12-18 parts of astragalus root, 12-18 parts of pilose asiabell root, 8-12 parts of perilla leaf, 8-12 parts of notopterygium root, 8-12 parts of paniculate swallowwort root, 8-12 parts of white mulberry root-bark, 9-12 parts of mung bean sprout, 5-7 parts of red paeony root, 5-7 parts of bitter orange, 5-7 parts of bupleurum root, 8-12 parts of albizia flower, 8-12 parts of wild jujube seed and 8-10 parts of liquorice. The traditional Chinese medicine composition provided by the invention takes prepared aconite, astragalus, and codonopsis pilosula as monarch drugs; perilla leaf, notopterygium root, paniculate swallowwort root and cortex mori radicis are used as ministerial drugs; the mung bean sprouts, red paeony root, bitter orange, radix bupleuri, flos albiziae and spina date seed are taken as adjuvant drugs; the licorice is used as a guiding drug, and through mutual compatibility and synergistic effect of the drugs, the composition not only can relieve symptoms of allergic rhinitis, but also can improve the overall condition of the organism and improve the life quality of patients.

Description

Traditional Chinese medicine composition for treating allergic rhinitis

Technical Field

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating allergic rhinitis.

Background

Allergic rhinitis, also known as allergic rhinitis, is a multifactorial disease caused by both genetic and environmental factors. It is mainly characterized by sudden and recurrent nasal obstruction, itching, sneeze and clear nasal discharge, and is called allergic rhinitis, allergic sneeze and allergic nose in traditional Chinese medicine, and is a common and frequently-occurring disease of the rhinology. For example, the "su wen, jin kui Zhen Lun" is: "spring good allergic bleeding" refers to the fact that winter does not press the heart, spring but does not press the heart. Questions about the following elements: the theory of alternating of qi is: the patient is allergic and cough due to the deficiency of the old wood. And the following steps: "your eyes are not in the same age, people's shoulders and back are in heavy weight, sneeze. The description of the disease in traditional Chinese medicine is first found in the west Zhou Shidai, the description of the ' Book of Rites ' month ' is recorded: ji Qiuhang summer-run, the Chinese water is stored in the winter, and the people are allergic to sneeze. It is recognized that natural climate abnormality is an important cause of allergic rhinitis.

The method for treating allergic rhinitis by using the traditional Chinese medicine is to benefit the lung, strengthen the spleen and tonify the kidney. The Chinese medicine and the acupuncture treatment have certain curative effects. Such as: one lung qi deficiency: modified Yupingfeng san and Xanthium sibiricum powder are added and modified. Two lung meridians are depressed and hot: the symptoms are cough, itching throat, dry mouth and dysphoria with smothery sensation. Flos Magnoliae lung-heat-clearing decoction is selected. Qi deficiency of the spleen: sijunzi decoction (prepared from Ginseng radix, rhizoma Atractylodis Macrocephalae, poria, and radix Glycyrrhizae Preparata) or powder of Ginseng radix, poria, and rhizoma Atractylodis Macrocephalae, fructus Chebulae, fructus Schisandrae chinensis, flos Magnoliae, and radix astragali can be added. For patients with excessive sneeze, periostracum Cicadae and Lumbricus can be added; for nasal discharge, fructus Tritici Levis and radix oryzae Glutinosae can be added. Four kidney-yang deficiency: can be used in the form of pill for treating kidney qi, walnut, cistanche salsa, raspberry, cherokee rose fruit, gecko, etc. The daily medication is mainly astragalus root, cocklebur fruit, dark plum fruit, dahurian angelica root, white atractylodes rhizome, magnolia flower, etc.

The Chinese patent literature also discloses some traditional Chinese medicine compositions for treating allergic rhinitis, such as:

CN200610075625.X A medicine for treating rhinitis and its preparation method, referring to radix astragali, notopterygii rhizoma, radix Angelicae Dahuricae, radix Glycyrrhizae Preparata, cortex Mori etc., has effects of dispelling pathogenic wind, inducing resuscitation, clearing heat, removing toxic substances, nourishing lung and kidney, and has obvious curative effects on rhinitis, allergic rhinitis, nasal polyp, hypertrophic rhinitis, atrophic rhinitis.

The Chinese medicinal composition for treating the allergic rhinitis has the effects of moistening lung, dispelling cold, relieving stuffy nose, dispelling wind-damp, clearing heat, detoxicating, promoting blood circulation and removing blood stasis, and has remarkable curative effect and reliable effect on treating the allergic rhinitis.

CN 201310258776.9A Chinese medicinal composition for treating allergic rhinitis is prepared from radix astragali, radix Codonopsis, radix Paeoniae alba, scutellariae radix, bupleuri radix, rhizoma Ligustici Chuanxiong, glycyrrhrizae radix, etc. Although the white paeony root, the baical skullcap root, the Chinese thorowax root and the szechuan lovage rhizome all have the effects of soothing liver and relieving depression, the invention mainly assists mutually in acting, and has the effects of clearing heat and detoxicating, freeing lung and inducing resuscitation, relieving exterior syndrome and dispelling cold, dispelling wind and removing dampness.

The traditional Chinese medicine is prepared from the traditional Chinese medicine prescription which is prepared from 15g of white peony root, 15g of raw astragalus root, white atractylodes rhizome, ledebouriella root, chinese angelica, magnolia flower, schisandra fruit, grassleaf sweelflag rhizome each 10g, cicada slough, licorice root each 6g and asarum herb 3 g; the second type consists of 20g of dark plum fruit, 15g of cocklebur fruit, 30g of astragalus root, 12g of magnolia flower, 10g of dahurian angelica root, ledebouriella root and schizonepeta herb respectively, 9g of largehead atractylodes rhizome, 9g of myrobalan respectively, 6g of bupleurum root and peppermint respectively, 3g of ephedra herb and 2g of manchurian wildginger.

The main ingredients of the commonly used Chinese patent medicines, such as the orifice-opening rhinitis tablet, comprise fructus Xanthii, radix sileris, radix astragali, radix angelicae, flos magnoliae, rhizoma atractylodis macrocephalae (stir-fried) and mint. Has effects of dispelling pathogenic wind, consolidating superficial resistance, dispersing lung qi, and inducing resuscitation.

In view of the long history and abundant experience of traditional Chinese medicine in treating allergic rhinitis, the latter people search and arrange the traditional Chinese medicine literature treasures, which are all inherited a certain traditional Chinese medicine genre, and explore and innovate the prescription. Since improving the mental state of a patient plays a vital role in the treatment of traditional Chinese medicine. The improvement not only can enhance the self-confidence of the patient and make the patient more positively cooperate with the treatment, but also can promote the self-repairing capability of the body to a certain extent, thereby improving the treatment effect. For example, the mental state of the patient can be improved, so that qi and blood are smooth, and the illness state is relieved; can improve vital qi, strengthen resistance, relax pleasure, relieve pain and discomfort, thereby improving the confidence of traditional Chinese medicine treatment and accelerating recovery.

However, in the prior art, most of the medicines are used for treating the inflammatory symptoms of the allergic rhinitis, and at most some Chinese medicines for soothing liver and relieving depression are used for treating the inflammation in a matched manner, such as CN201310258776.9 and the like, and the bidirectional re-use of medicines for treating the inflammatory symptoms of the allergic rhinitis and relieving anxiety and emotion is not found.

Disclosure of Invention

The present inventors believe that the main cause of allergic rhinitis is hypoimmunity. Allergic rhinitis is caused by pathogenic wind-cold and nasal orifices on the basis of deficiency of yang qi of lung, spleen and kidney. Because the influence of allergic rhinitis on the daily life of a patient is moment and moment, the patient is easy to generate mental anxiety and emotion, thereby affecting the treatment effect of the traditional Chinese medicine on allergic rhinitis inflammation. Therefore, in the treatment of allergic rhinitis, it is important to improve the mental state of the patient.

In view of the defects and shortcomings of the prior art, the invention adopts the method of treating inflammatory symptoms of allergic rhinitis and relieving anxiety and emotion bi-directionally and re-medication caused by the allergic rhinitis, and provides a traditional Chinese medicine composition for treating the allergic rhinitis, which is particularly used for treating the allergic rhinitis caused by yang deficiency, qi deficiency, wind cold, damp evil, lung heat, blood stasis and other factors, and simultaneously has symptoms of headache, chest distress, anxiety, insomnia and the like caused by the allergic rhinitis.

The technical scheme of the invention is as follows:

A Chinese medicinal composition for treating allergic rhinitis is prepared from radix Aconiti lateralis Preparata, radix astragali, and radix Codonopsis as principal drugs; perilla leaf, notopterygium root, paniculate swallowwort root and cortex mori radicis are used as ministerial drugs; the mung bean sprouts, red paeony root, bitter orange, radix bupleuri, flos albiziae and spina date seed are taken as adjuvant drugs; glycyrrhrizae radix is used as guiding drug. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of prepared aconite root, 12-18 parts of astragalus root, 12-18 parts of pilose asiabell root, 8-12 parts of perilla leaf, 8-12 parts of notopterygium root, 8-12 parts of paniculate swallowwort root, 8-12 parts of white mulberry root-bark, 9-12 parts of mung bean sprout, 5-7 parts of red paeony root, 5-7 parts of bitter orange, 5-7 parts of bupleurum root, 8-12 parts of albizia flower, 8-12 parts of wild jujube seed and 8-10 parts of liquorice.

Further, the traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 8-10 parts of prepared aconite root, 12-15 parts of astragalus root, 12-15 parts of pilose asiabell root, 8-10 parts of perilla leaf, 8-10 parts of notopterygium root, 8-10 parts of paniculate swallowwort root, 8-10 parts of white mulberry root-bark, 9-11 parts of red bean sprout, 5-6 parts of red paeony root, 5-6 parts of bitter orange, 5-6 parts of bupleurum root, 8-10 parts of albizia flower, 8-10 parts of wild jujube seed and 8-9 parts of liquorice.

Further, the traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 10-12 parts of prepared aconite root, 15-18 parts of astragalus root, 15-18 parts of pilose asiabell root, 10-12 parts of perilla leaf, 10-12 parts of notopterygium root, 10-12 parts of paniculate swallowwort root, 10-12 parts of white mulberry root-bark, 11-12 parts of mung bean sprout, 6-7 parts of red paeony root, 6-7 parts of bitter orange, 6-7 parts of bupleurum root, 10-12 parts of albizia flower, 10-12 parts of wild jujube seed and 9-10 parts of liquorice.

Further, the traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 10 parts of prepared aconite root, 15 parts of astragalus root, 15 parts of pilose asiabell root, 10 parts of perilla leaf, 10 parts of notopterygium root, 10 parts of paniculate swallowwort root, 10 parts of white mulberry root-bark, 11 parts of mung bean sprout, 6 parts of red paeony root, 6 parts of bitter orange, 6 parts of radix bupleuri, 10 parts of albizia flower, 10 parts of wild jujube seed and 9 parts of liquorice.

Further, the mass requirements of the raw materials are as follows:

preparing radix aconiti lateralis preparata: stewing the aconite, wherein the middle dam of Jiang oil county and the producer of Zhangming county in Sichuan province are medicinal materials in the road and are stewed with ginger;

Radix astragali: cleaning, cutting, namely adopting a genuine medicinal material astragalus membranaceus, wherein the content of effective components of astragaloside IV and calycosin is not less than 2 times of pharmacopoeia standards;

radix codonopsis pilosulae: cutting into pieces, and adopting radix Codonopsis or radix Codonopsis;

Notopterygium root: cutting, wherein the yield of Sichuan province is genuine medicinal material, and the volatile oil content is not less than 3.0%;

the mung bean sprouts: bud method, alcohol soluble extract is not less than 12%;

radix paeoniae rubra: cutting, wherein the Torongeur of the inner Mongolia autonomous region is medicinal material, and the paeoniflorin content is not less than 2.5%;

fructus Aurantii: honey-roasted, wherein the Jiangxi province producer is a genuine medicinal material, and the naringin content is not less than 8.0%;

Bupleurum root: cutting, and making mountain western province land medicinal material with purity not lower than 97%;

albizia flower: selecting, wherein the content of quercetin is not less than 1.0%;

Semen Ziziphi Spinosae: the content of spinosin is not less than 0.10%;

Licorice root: cutting, wherein the cotton flag and Lingwu, the prison, and the Confucius are produced as genuine products with glycyrrhizic acid content of not less than 2.5%.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating allergic rhinitis, which comprises the following steps: mixing all the raw materials according to the parts by weight, adding water for decoction, filtering and concentrating after the decoction is finished.

Further, the preparation method of the traditional Chinese medicine composition for treating allergic rhinitis comprises the following steps:

S1, soaking: soaking prepared aconite in water according to the parts by weight to obtain a first product, and soaking other raw material medicines except the prepared aconite in water according to the parts by weight to obtain a second product;

s2, decocting: firstly, decocting a first product, then adding a second product, and continuously decocting;

And S3, filtering and concentrating after the decoction is finished, thus obtaining the traditional Chinese medicine.

Further, in the step S1, the water consumption for soaking the prepared aconite is 150-250 parts, and the water consumption for soaking the raw materials except the prepared aconite is 800-1000 parts; in the step S2, the first decoction time is 30-60min, and the second decoction time is 35-45min.

The invention also provides a pharmaceutical preparation comprising the traditional Chinese medicine composition for treating allergic rhinitis.

The medicinal preparation is decoction, tablets, granules, pills, powder, capsules or oral liquid. Preferably, the pharmaceutical preparation is a decoction.

The invention also provides application of the traditional Chinese medicine composition in preparing medicines for treating allergic rhinitis.

The traditional Chinese medicine composition for treating allergic rhinitis can be directly or indirectly added into various pharmaceutically acceptable common auxiliary materials such as filling agents, disintegrating agents, lubricants, adhesives and the like required by preparing different dosage forms by a person skilled in the art, and is prepared into a common pharmaceutical preparation by a conventional pharmaceutical preparation method.

The preparation method of the traditional Chinese medicine composition decoction for treating the allergic rhinitis comprises the following steps:

(1) Soaking: soaking the prepared aconite root in 150-250 parts by weight of water for 30-45min to enable the medicinal materials to fully absorb water to obtain a first product, and soaking the other raw material medicines except the prepared aconite root in 800-1000 parts by weight of water for 30-45min to enable the medicinal materials to fully absorb water to obtain a second product;

(2) Decocting: firstly decocting the first product for 30-60min, then adding the second product and continuously decocting for 35-45min;

(3) And (3) filtering: filtering after decoction, and separating the medicinal liquid from the residue to obtain the original medicinal liquid;

(4) Concentrating: concentrating the original liquid medicine obtained in the step (3) to 360 parts of liquid medicine;

(5) And (3) packaging: and (3) packaging 360 parts of the liquid medicine obtained in the step (4) into 180ml of each bag, and obtaining the decoction by one dose.

The beneficial effects of the invention are as follows:

1. In the theory of traditional Chinese medicine, emotion is closely related to viscera functions, and improvement of mental state can directly influence normal operation of viscera functions, so that self-repairing capability of an organism is enhanced. For allergic rhinitis patients, symptoms frequently accompanied by breathing often lead to high mental stress and emotional anxiety, and the bad mental state can in turn aggravate rhinitis symptoms and form vicious circle. Therefore, in the treatment of allergic rhinitis, the functions of regulating qi and blood, soothing nerves and calming mind and relieving anxiety can be achieved by regulating the function of dredging qi and blood, so as to promote qi and blood circulation, calm emotion and relax. The good mental state can also promote metabolism and toxin expelling function of the organism, so that waste and toxin in the organism can be cleared in time, a more favorable environment is provided for self-repairing of the organism, and the treatment effect is improved.

The traditional Chinese medicine composition is based on the whole treatment concept of the traditional Chinese medicine, follows the treatment principle of 'tonifying lung, strengthening spleen and tonifying kidney', pays attention to the internal environment of the organism, treats the main symptoms of allergic rhinitis, and simultaneously pays attention to relieving anxiety and emotion of a patient caused by diseases, so that the bidirectional regulation of inflammatory symptoms and psychological states is realized. The formula structure comprises: the ministerial drugs of perilla leaf, notopterygium root, paniculate swallowwort root and white mulberry root bark can assist monarch drugs of prepared aconite root, astragalus root and pilose asiabell root to better play the roles of warming yang, tonifying qi, strengthening body resistance and consolidating constitution, and meanwhile, the effects of dispelling wind, dispelling cold and relieving stuffy nose can also effectively relieve the main symptoms of allergic rhinitis. The auxiliary medicines of the red bean sprouts, the red paeony root, the fructus aurantii, the radix bupleuri, the flos albiziae and the spina date seed can further supplement the effects of the monarch drug in warming yang, tonifying qi, strengthening body resistance and consolidating constitution, and meanwhile, the effects of soothing liver, relieving depression, promoting qi circulation, activating blood circulation, soothing nerves and stabilizing mind can improve the mental state of a patient, relieve anxiety and emotion and provide a good psychological environment for treating allergic rhinitis. The adjuvant and the ministerial drugs complement each other in action, and the adjuvant has the effects of soothing liver and relieving depression, promoting qi and activating blood circulation, soothing nerves and stabilizing the mind, can assist the ministerial drugs to better play the roles of dispelling wind and cold and promoting the circulation of nose and orifices, and is also helpful for relieving the emotion problem caused by allergic rhinitis.

The principal drug is used for warming yang, tonifying qi, strengthening body resistance and strengthening body resistance, and enhancing the immunity of the organism, and is the treatment principal; the ministerial drugs aim at dispelling wind and cold, relieving stuffy nose and directly aiming at symptoms such as nasal obstruction, nasal itching, sneeze and the like of allergic rhinitis; the adjuvant is used for soothing liver, relieving depression, promoting qi and blood circulation, and harmonizing internal environment of organism; at the same time, the nerve soothing and the mind stabilizing are repeated, and the anxiety emotion of the patient caused by the diseases is relieved. The medicines are blended to strengthen the overall curative effect.

2. The traditional Chinese medicine composition is based on warming yang and tonifying qi, strengthening body resistance and consolidating constitution, and can directly relieve inflammatory symptoms of allergic rhinitis, such as symptoms of nasal obstruction, nasal itching, sneeze and the like by a treatment mode of dispelling wind and cold and relieving nasal orifices; meanwhile, the medicine for soothing liver and relieving depression, promoting qi and activating blood circulation and soothing nerves and stabilizing mind is assisted to harmonize the internal environment of the organism and relieve anxiety and emotion of patients caused by diseases. The medicines are combined together to play roles of tonifying lung, strengthening spleen and tonifying kidney, so that the effects of treating inflammatory symptoms of allergic rhinitis and relieving anxiety and emotion are achieved in a bidirectional and combined way. A new therapeutic regimen is developed that focuses not only on the treatment of inflammatory symptoms of allergic rhinitis but also on the improvement of overall health and mental state of the patient. The therapeutic principle of the treatment method reflects the overall therapeutic concept and dialectical therapeutic principle of traditional Chinese medicine, provides a more comprehensive and effective therapeutic scheme for patients, and has important contribution to the prior art.

Detailed Description

The following description will clearly and fully describe the technical solutions of the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.

Unless otherwise specified, all reagents involved in the examples of the present invention are commercially available products and are commercially available.

According to the principles of syndrome differentiation and treatment and syndrome following dosage, the embodiment of the invention provides a traditional Chinese medicine composition basic recipe for treating allergic rhinitis by considering the properties, compatibility, dosage form and applicable factors of traditional Chinese medicine composition and raw material medicines, and the like:

The basic recipe takes prepared aconite root, astragalus root and pilose asiabell root as monarch drugs; perilla leaf, notopterygium root, paniculate swallowwort root and cortex mori radicis are used as ministerial drugs; the mung bean sprouts, red paeony root, bitter orange, radix bupleuri, flos albiziae and spina date seed are taken as adjuvant drugs; glycyrrhrizae radix is used as guiding drug.

The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of prepared aconite root, 12-18 parts of astragalus root, 12-18 parts of pilose asiabell root, 8-12 parts of perilla leaf, 8-12 parts of notopterygium root, 8-12 parts of paniculate swallowwort root, 8-12 parts of white mulberry root-bark, 9-12 parts of mung bean sprout, 5-7 parts of red paeony root, 5-7 parts of bitter orange, 5-7 parts of bupleurum root, 8-12 parts of albizia flower, 8-12 parts of wild jujube seed and 8-10 parts of liquorice.

The raw material medicaments used in the basic recipe all meet the requirements of pharmacopoeia (2020 edition) of the people's republic of China published by Chinese medical science and technology Press (abbreviated as pharmacopoeia).

Some crude drugs are required in the following table 1.

TABLE 1

Note that: in table 1, "%" means mass percent.

Example 1

The formula of the traditional Chinese medicine composition for treating allergic rhinitis comprises the following components: 10g of prepared aconite root, 15g of astragalus root, 15g of pilose asiabell root, 10g of perilla leaf, 10g of notopterygium root, 10g of paniculate swallowwort root, 10g of white mulberry root-bark, 11g of small red bean sprout, 6g of red paeony root, 6g of bitter orange, 6g of bupleurum root, 10g of silktree albizia flower, 10g of wild jujube seed and 9g of liquorice.

The preparation method of the traditional Chinese medicine composition for treating allergic rhinitis comprises the following steps:

in order to ensure that the active ingredients of the medicine are fully released and simultaneously bring convenience to patients to take, the medicine is prepared by adopting an intra-hospital mechanism decoction method.

The preparation method of the mechanical decoction comprises the following steps:

S1, soaking: s11, firstly, preparing prepared aconite according to a formula, putting the prepared aconite into a decocting container of a decocting machine, adding 200ml of water, and soaking for 40 minutes to enable the medicinal materials to fully absorb water;

S12, putting astragalus, codonopsis pilosula, perilla leaf, notopterygium root, paniculate swallowwort root, white mulberry root-bark, mung bean sprout, red paeony root, bitter orange, bupleurum, albizia flower, spina date seed and liquorice into another container according to a formula, adding 900ml of water, and soaking for 40 minutes to enable the medicinal materials to fully absorb water.

S2, decocting: firstly, decocting the substance obtained in the step S11 by using a decoction machine, wherein the decoction temperature is 100 ℃, and the decoction time is controlled to be 45 minutes; and adding the obtained product of S12, continuously decocting at 100 ℃ for 40 minutes.

S3, filtering: after the decoction is completed, the liquid medicine is separated from the medicine residues by the filtering equipment of the medicine decocting machine.

S4, concentrating: concentrating the liquid medicine obtained in the step S3 to obtain the medicine.

Preparation of a traditional Chinese medicine composition decoction for treating allergic rhinitis:

Concentrating the obtained Chinese medicinal composition liquid to 360ml, and packaging into 180ml per bag, wherein the dosage is one dose for patients to take.

Example 2

The formula of the traditional Chinese medicine composition for treating allergic rhinitis comprises the following components: prepared aconite root 8g, astragalus root 12g, pilose asiabell root 12g, perilla leaf 8g, notopterygium root 8g, paniculate swallowwort root 8g, mulberry bark 8g, mung bean sprout 9g, red peony root 5g, bitter orange 5g, bupleurum root 5g, albizia flower 8g, wild jujube seed 8g and licorice root 8g.

s1, soaking: s11, firstly, preparing prepared aconite according to a formula, putting the prepared aconite into a decocting container of a decocting machine, adding 150ml of water, and soaking for 30 minutes to enable the medicinal materials to fully absorb water;

S12, putting astragalus, codonopsis pilosula, perilla leaf, notopterygium root, paniculate swallowwort root, white mulberry root-bark, mung bean sprout, red paeony root, bitter orange, bupleurum, albizia flower, spina date seed and liquorice into another container according to a formula, adding 800ml of water, and soaking for 30 minutes to enable the medicinal materials to fully absorb water.

S2, decocting: firstly, decocting the substance obtained in the step S11 by using a decoction machine, wherein the decoction temperature is 100 ℃, and the decoction time is controlled to be 30 minutes; and adding the obtained product of S12, continuously decocting at 100 ℃ for 35 minutes.

Example 3

The formula of the traditional Chinese medicine composition for treating allergic rhinitis comprises the following components: prepared aconite root 12g, astragalus root 18g, pilose asiabell root 18g, perilla leaf 12g, notopterygium root 12g, paniculate swallowwort root 12g, mulberry bark 12g, mung bean sprout 12g, red peony root 7g, bitter orange 7g, bupleurum root 7g, albizia flower 12g, wild jujube seed 12g and licorice root 10g.

s1, soaking: s11, firstly, preparing prepared aconite according to a formula, putting the prepared aconite into a decocting container of a decocting machine, adding 250ml of water, and soaking for 45 minutes to enable the medicinal materials to fully absorb water;

S12, putting astragalus, codonopsis pilosula, perilla leaf, notopterygium root, paniculate swallowwort root, white mulberry root-bark, mung bean sprout, red paeony root, bitter orange, bupleurum, albizia flower, spina date seed and liquorice into another container according to a formula, adding 1000ml of water, and soaking for 45 minutes to enable the medicinal materials to fully absorb water.

S2, decocting: firstly, decocting the substance obtained in the step S11 by using a decoction machine, wherein the decoction temperature is 100 ℃, and the decoction time is controlled to be 60 minutes; and adding the obtained product of S12, continuously decocting at 100 ℃ for 45 minutes.

1. Clinical observation report of the traditional Chinese medicine composition for treating allergic rhinitis

Case selection

1. Case inclusion criteria:

Referring to the diagnosis standard of allergic rhinitis in the Chinese people's republic of China Chinese medicine industry standard ' traditional Chinese medicine disease diagnosis curative effect standard ': (1) Inquiring about the medical history in detail, the related etiology is sought for the past medical history and family history, especially allergic diseases. (2) The nose itching, continuous sneeze, nasal obstruction, clear nasal discharge and other symptoms are mainly manifested. (3) Nasal examination revealed pale nasal mucosa, edema, and water-like secretions in the nasal passages. (4) The allergen skin test is positive, or the allergen-specific IgE antibody detection is positive. (5) Has obvious seasonality and territory, or is easy to be started after the allergen is contacted. Can be accompanied with eye symptoms such as itching of eyes, conjunctival congestion, lacrimation, etc., and respiratory tract symptoms such as chest distress, cough, asthma, etc.

2. Case exclusion criteria:

(1) Other nasal diseases cause similar symptoms such as sinusitis, deviation of the nasal septum, and the like. (2) Nose symptoms caused by infectious diseases, such as common cold, influenza, etc. (3) Nasal symptoms associated with systemic diseases, such as endocrine system diseases, immune system diseases, etc. (4) nasal symptoms caused by adverse drug reactions. (5) recent history of nasal surgery. There are serious heart, liver, kidney and other organ dysfunctions; patients with mental disorders or are taking psychotic drugs that may affect nasal symptoms. (6) patients who do not cooperate with diagnosis and treatment; patients whose medical records are incomplete or whose allergens are not known.

(II) study methods.

The grouping method comprises the following steps: 120 patients meeting the inclusion standard, who are received by a Fuzhou Chinese medical hospital (affiliated hospital of advanced special department of traditional Chinese medicine in Jiangxi) and other cooperative units in the city of Fuzhou, are pre-selected as study objects, and the ages are 14-60. The medicines are divided into 2 groups, 60 treatment groups (Chinese medicinal composition decoction prepared in the embodiment 1 of the invention) and 60 control groups (orifice-opening rhinitis tablet).

During the study period, data for 3 patients in the treatment group were not collected and data for 2 patients were not collected all for various reasons; the data of 5 patients in the control group are not collected, and the data of 3 patients are not collected completely; in order not to affect the study, 100 patients meeting inclusion criteria were determined as subjects for clinical observation study according to a given protocol, 50 for each of the treatment group and the control group, wherein: the control groups of the treatment group were 14-19 years old 20 cases, 20-30 years old 20 cases, 31-60 years old 10 cases, respectively. The age, sex and illness state of the two groups of patients are not obviously different, and the patients are comparable.

(III) treatment method:

Treatment group: the Chinese medicinal composition decoction of the embodiment 1 of the invention is taken orally, the decoction is taken orally once a day, and the decoction is taken warm after breakfast and supper, and the dosage of certain Chinese medicaments can be specifically adjusted according to the principle of dialectical treatment.

Control group: rhinitis tablet for resuscitation (film coated tablet, yellow brown to tan after removing film coating; slightly bitter, pungent and cool in taste. Chinese medicine standard character Z19993122, aluminum-plastic plate.20 pieces/plate×4 plates/box. Jiangxi doctor reaches pharmaceutical industry Co., ltd.). Is orally taken. 5-7 tablets at a time, 3 times a day. Following the order, the doses specified in the instructions are taken.

The treatment course of the treatment group and the control group is 2-3 treatment courses, and each treatment course is 5-7 days.

The control groups of the treatment groups are in accordance with the attention points of Chinese patent medicines of Chinese traditional medicines.

(IV) curative effect standard:

1. The following factors are considered in assessing efficacy:

(1) Severity of symptoms: such as nasal itching, sneezing, nasal obstruction, nasal discharge, etc.

(2) And comparing clinical curative effects.

(3) Frequency of onset: it was observed whether the number of symptom attacks was reduced.

(4) Influence on daily life: and evaluating whether the influence of the disease condition on the life quality is reduced.

(5) Nasal cavity examination results: including restoration of nasal mucosa, etc.

(6) Duration of time: duration of symptomatic relief or disappearance.

2. Referring to the allergic rhinitis curative effect evaluation standard in the traditional Chinese medicine medical industry standard of the people's republic of China:

And (3) healing: symptoms and signs completely disappear, and no recurrence occurs in half a year after follow-up.

The effect is shown: the symptoms and signs are obviously improved, and the frequency of attacks is reduced.

The method is effective: symptoms and signs are improved.

Invalidation: no improvement or exacerbation of symptoms or signs.

3. Results show that

The test results for both the treatment and control groups are expressed as intra-group averages.

(V) clinical results.

1. Symptom improvement condition:

The results of the improvement of symptoms after treatment are shown in Table 2. The symptoms of nasal itching, sneeze, nasal obstruction, nasal discharge and the like of the patients in the treatment group and the control group are improved to different degrees. This shows that the symptom improvement degree of the patients in the treatment group of the traditional Chinese medicine composition is obviously superior to that of the control group.

Table 2 comparison of the extent of remission of symptoms in two groups of patients

Symptom scores were made in 0-10 minutes, 0 indicating no symptoms and 10 indicating the most severe symptoms, and were as follows:

0 point: no symptoms such as itching, sneezing, nasal obstruction, nasal discharge and the like;

1-3: ① Slight itching, occasional occurrence, no influence on daily life, ② occasional sneezing, no influence on daily life, ③ slight nasal obstruction, occasional occurrence, no influence on respiration, ④ small amount of runny nose, occasional occurrence;

4-6 minutes: ① Moderate rhinocnesmus often occurs, sometimes affects daily life, ② sneezes frequently is higher, sometimes affects daily life, ③ moderate nasal obstruction often occurs, and affects breathing, ④ moderate rhinorrhea often occurs;

7-10 minutes: ① Severe itching of nose, sustained, severe effects on daily life, ② frequent sneezing, sustained, severe effects on daily life, ③ severe nasal congestion, sustained, severe effects on breathing and sleep, ④ massive nasal discharge, sustained, and frequent wiping.

2. Clinical efficacy comparison:

The results are shown in tables 3 and 4, the proportion of cured patients in the treatment group is 60%, the proportion of effective patients is 30%, the proportion of effective patients is 8%, and the proportion of ineffective patients is 2%; the proportion of cured patients in the control group is 30%, the proportion of effective patients is 40%, the proportion of effective patients is 20%, and the proportion of ineffective patients is 10%. The curative effect of the traditional Chinese medicine composition treatment group is obviously better than that of a control group.

Table 3 comparison of clinical efficacy of two groups of patients (number of examples)

Table 4 comparison of clinical efficacy of two groups of patients (%)

3. Frequency of onset:

the results are shown in Table 5, in which the number of symptomatic attacks was reduced in both groups, the treatment group had a reduction of 7.5 times/month, the improvement degree was 70.09%, the control group had a reduction of 5.3 times/month, and the improvement degree was 52.48%. The occurrence frequency of the traditional Chinese medicine composition treatment group is obviously reduced compared with that of the control group.

Table 5 comparison of seizure frequency for two groups of patients

4. Influence on daily life:

The results are shown in Table 6, the influence of the patient on the psychological state, sleep and other life quality is obviously reduced, the score for improving the psychological state of the treatment group is improved by 18 points, and the score of the control group is improved by 13 points; the score of sleep quality improvement of the treatment group was increased by 33 points, and the score of the control group was increased by 19 points.

TABLE 6 comparison of the influence of the conditions of two groups of patients on quality of life (division)

Wherein:

(1) Mental state is re-average as determined by anxiety self-rating scale (SAS) score. The anxiety self-evaluation scale may provide information on anxiety degree, anxiety frequency, anxiety intensity, anxiety duration, anxiety triggers (focusing on which factors may trigger or exacerbate anxiety in asking for allergic rhinitis), anxiety body reactions (evaluating physiological reactions caused by anxiety, focusing on reactions to symptoms of allergic rhinitis, etc.), anxiety thinking patterns, anxiety behavior manifestations (evaluating behavioral reactions when anxiety, focusing on compulsive behaviors caused by symptoms of allergic rhinitis, etc.), life influences by anxiety, and seeking to help will, etc.

The SAS standard score has a demarcation value of 50 points, wherein: ① 50-59 are classified as mild anxiety: psychological stress may exist but without obvious anxiety symptoms. ② 60-69 are classified as moderate anxiety: obvious anxiety symptoms may exist and may have a certain influence on daily life. ③ 70 and above are severe anxiety: there are significant anxiety symptoms that severely interfere with and affect life and work.

The treatment group is superior to the control group in terms of improvement of symptoms of allergic rhinitis and alleviation of anxiety and tension.

(2) The influence score of the sleep quality is 100 minutes, the higher the score is, the better the life quality is, and the index and the scoring basis for evaluating the influence of the sleep quality are as follows:

① Sleep time (20 minutes): fall asleep within 5 minutes: 20 minutes; sleep for 5-15 minutes: 15 minutes; sleep for 15-30 minutes: 10 minutes; falling asleep for more than 30 minutes: 5 minutes. ② Night arousal (20 points): no arousal: 20 minutes; wakes 1 time and lasts short: 15 minutes; wakes 1-2 times and lasts for a medium period: 10 minutes; wakefulness is longer than 2 times or for a long time: 5 minutes. ③ Sleep duration (15 minutes): 7-9 hours: 15 minutes; 6-7 hours or 9-10 hours: 10 minutes; 5-6 hours or 10-11 hours: 5 minutes; less than 5 hours or more than 11 hours: 0 minutes. ④ Sleep depth/quality (20 minutes): no nightmare, snoring and apnea: 20 minutes; occasional nightmares, slight snoring: 15 minutes; frequent nightmares, moderate snoring or apnea: 10 minutes; severe nightmares, severe snoring or apnea: 5 minutes. ⑤ Post-wake sensation (15 points): is energetic and clear in brain: 15 minutes; feel is general: 10 minutes; tired and drowsy: 5 minutes. ⑥ Hypnotics (10 minutes): never use: 10 minutes; occasional use: 5 minutes; frequent use or reliance on: 0 minutes.

5. Duration of time:

The results are shown in Table 7, and the treatment group patients had a maintenance time for symptom relief or disappearance of 3.5 months, which is significantly longer than 2.1 months for the control group. Time required for symptomatic relief: the treatment group required 7.2 days for symptomatic relief and the control group 10.5 days. The treatment group is shown to have longer maintenance time after symptom relief or disappearance, and the treatment effect is shown to be longer lasting, and the treatment group is also better than the control group in symptom relief speed.

Table 7 duration comparison of two groups of patients

6. Nasal cavity examination results:

The results are shown in Table 8, the proportion of pale nasal mucosa and edema of the patients in the treatment group is 80.47% and the proportion of visible water-like secretion in the nasal passages is 75.31% before treatment; the control group had a pale nasal mucosa, a edema ratio of 78.35% and a nasal meatus visible water-like secretion ratio of 72.49%. After treatment, the proportion of pallor and edema of nasal mucosa of the treated patients was reduced to 25.55% and the proportion of watery secretion of nasal passages was reduced to 15.63%; the proportion of pale nasal mucosa and edema of the control group was reduced to 50.75%, and the proportion of watery secretion of the nasal passages was reduced to 40.69%.

Table 8 comparison of nasal cavity examination results for two groups of patients

The analysis results in table 8 show that the improvement of the treatment group on the pale nasal mucosa, the edema proportion and the visible water-like secretion proportion of the nasal passages is obviously superior to that of the control group, and the improvement of the treatment group on each index is obviously superior to that of the control group.

2. Typical case reporting

Case report 1

1. Patient basic information

Name: mr. prune;

Age: age 27;

Occupation: IT engineers.

2. Complaints and medical history

Complaints: the symptoms of nasal obstruction, nasal itching, sneezing and runny nose, which have seriously affected their daily lives and works, have repeatedly appeared in patients since the last half a year.

Medical history: half a year ago, mr. Prune began to present symptoms of allergic rhinitis due to great working pressure and irregular life work and rest. He tried western medicine and nasal spray treatment many times, but symptom relief was not obvious, and worry about side effects of long-term western medicine treatment.

3. Pre-treatment condition

(1) Symptom condition: the nasal obstruction is serious, and frequent nose blowing is required; itching is difficult to endure, often resulting in frequent sneezing; the nasal discharge is continuous, and a large amount of paper towels are needed. The pre-treatment symptom score was 8.43 points.

(2) Frequency of onset: the symptoms are obviously aggravated in the morning and evening and in the weather, the attack frequency is high, and the average monthly attack frequency is 10.77 times.

(3) Psychological state: the patient has low emotion, anxiety and anxiety, and the working efficiency is reduced. The effect of the disease on mental state was scored 70.05 points.

(4) Sleep quality: nasal obstruction is serious at night, so that the sleeping is shallow, the sleeping is easy to wake, and the mental retardation is caused the next day. The effect of the condition on sleep quality was scored 56.00 points.

(5) Nasal cavity examination results: edema ratio 75.49%, nasal meatus visible water-like secretion ratio 60.89%.

4. Treatment process

The Chinese medicinal composition of the invention is administered to patients for treatment, and decoction is prepared according to the method of 'example 1', and is taken twice a day in the morning and evening.

5. Post-treatment conditions

(1) Symptom relief condition:

After one week: the symptoms of nasal obstruction and nasal itching are obviously relieved, the number of times of sneeze is reduced, and the amount of clear nasal discharge is correspondingly reduced. The symptom score was reduced to 5.11 points after treatment.

Two weeks later: the symptoms are further relieved, the nasal obstruction at night is obviously improved, and the sleep quality is improved. The symptom score was reduced to 3.25 points.

Three weeks later: the symptoms basically disappear, the patient feels good from the description, and the life quality is obviously improved. The symptom score was reduced to 1.29 points.

(2) Nasal cavity examination results:

one week after treatment: the edema ratio was reduced to 50.09% and the nasal meatus visible watery secretion ratio was reduced to 30.29%.

Two weeks after treatment: the edema ratio was further reduced to 30% and the nasal meatus visible watery secretion ratio was reduced to 15.01%.

Three weeks after treatment: the nasal mucosa is basically recovered to be normal, and obvious congestion edema and secretion are not seen.

(3) Emotional state improvement:

With the improvement of symptoms, the emotion of the patient is gradually improved, and the anxiety emotion is obviously relieved. The working efficiency is improved, is engaged with the colleague relationship. Later treatment test, the influence score of the illness on the psychological state is 41.77 points, and the influence score of the illness on the sleep quality is 77.11 points

6. Conclusion(s)

The case report details the change of the disease condition of a patient with moderate allergic rhinitis after the treatment by using the traditional Chinese medicine composition. After three weeks of treatment, the symptoms of the patients are basically disappeared, and the quality of life is obviously improved. The result proves the effectiveness of the traditional Chinese medicine composition in treating allergic rhinitis, and provides a new treatment option for patients with allergic rhinitis.

(II) case report II

1. Basic condition of patient

Patient name: mr. Creep;

age: age 19;

Occupation: a student.

2. Complaints and medical history

Complaints: patients complain about nasal obstruction, itching nose, frequent sneezes with clear nasal discharge, symptoms lasting for about 3 months, especially aggravated in the morning and evening and when the weather changes, and the working state is bad.

Medical history: patients have no history of allergy, and patients with allergic rhinitis are in family.

3. Pre-treatment condition

(1) Symptom condition: patients have serious nasal obstruction, nasal itching and frequent sneeze, and the nasal discharge is required to be wiped by paper towels for a plurality of times every day. The average symptom score before treatment was 6.83 points.

(2) Frequency of onset: the symptoms are obviously aggravated in the morning and evening and in the weather, the attack frequency is high, and the average monthly attack frequency is 8.79 times.

(3) Psychological state: the patient has low emotion, anxiety and anxiety, and the working efficiency is reduced. The effect of the disease on mental state was scored 67.09 points.

(4) Sleep quality: nasal obstruction is serious at night, so that the sleeping is shallow, the sleeping is easy to wake, and the mental retardation is caused the next day. The effect of the condition on sleep quality was scored 58.35 points.

(5) Nasal cavity examination results: edema ratio 74.51%, nasal meatus visible water-like secretion ratio 58.59%.

4. Treatment process

The Chinese medicinal composition of the invention is administered to patients for treatment, and decoction is prepared according to the method of 'example 2', and is taken twice a day in the morning and evening.

5. Post-treatment conditions

(1) Symptom relief condition:

after one week: the symptoms of nasal obstruction and nasal itching of patients are obviously relieved, the times of sneezing are reduced, and the secretion amount of nasal discharge is reduced. The symptom score was reduced to 3.85 points after treatment.

Two weeks later: the symptoms of nasal obstruction and nasal itching of patients basically disappear, the number of times of sneezing is obviously reduced, and the nasal discharge is almost avoided. The symptom score was reduced to 1.45 points.

(2) Nasal cavity examination results:

One week after treatment: the edema ratio was reduced to 35.01% and the nasal meatus visible water-like secretions ratio was reduced to 18.55%.

Two weeks after treatment: the edema ratio was further reduced to 2.73%, and the nasal mucosa was substantially restored to normal, with no apparent congestion edema and secretions.

(3) Emotional state improvement:

The emotion of the patient is gradually stabilized, the anxiety is reduced, and the working efficiency is improved. And in the later treatment test, the influence score of the illness state on the psychological state is 30.23 points, and the influence score of the illness state on the sleep quality is 91.21 points.

6. Conclusion(s)

The case report details the change of the disease condition of a patient suffering from early-onset mild allergic rhinitis after the treatment by using the traditional Chinese medicine composition. After half a month of treatment, the symptoms of the patients are basically disappeared, and the quality of life is obviously improved. The result proves that the traditional Chinese medicine composition has remarkable curative effect in the aspect of treating allergic rhinitis, can effectively relieve symptoms of patients, improves nasal conditions, and improves life quality of the patients.

(III) case report III

1. Basic condition of patient

Patient name: stretching women;

Age: age 47;

Occupation: and no.

2. Complaints and medical history

Complaints: women who complain about allergic rhinitis for five years continue to suffer from dysphoria and anxiety in recent years, and are accompanied by exacerbation of symptoms of allergic rhinitis such as nasal obstruction, watery nasal discharge, sneeze and the like.

Medical history: the patients have no similar medical history in young age, allergic rhinitis is frequently attacked in five years, symptoms are gradually aggravated in recent years, and the symptoms are obvious especially in the morning and evening and in weather changes. Various western medicines and traditional Chinese medicines (orifice-opening rhinitis tablets and the like) have been tried for treatment, but the effects are not ideal.

3. Pre-treatment condition

(1) Symptom condition: women mainly show nasal obstruction, watery nasal discharge, sneeze with symptoms of itching nose, itching eyes and the like. The average symptom score before treatment was 9.32 points.

(2) Frequency of onset: the symptoms are obviously aggravated in the morning and evening and in the weather, the attack frequency is high, and the average monthly attack frequency is 12.56 times.

(3) Psychological state: the patient has low emotion, anxiety and anxiety, and the working efficiency is reduced. The effect of the disease on mental state was scored 72.90 points.

(4) Sleep quality: nasal obstruction is serious at night, so that the sleeping is shallow, the sleeping is easy to wake, and the mental retardation is caused the next day. The effect of the condition on sleep quality was scored 45.23 points.

(5) Nasal cavity examination results: edema ratio 76.62%, nasal meatus visible water-like secretion ratio 68.45%.

4. Treatment process

The Chinese medicinal composition of the invention is administered to patients for treatment, and decoction is prepared according to the method of 'example 3', and is taken twice a day in the morning and evening.

5. Post-treatment conditions

(1) Symptom relief condition:

after one week: symptoms such as nasal obstruction, nasal discharge, sneeze and the like of patients are relieved, but the symptoms still exist. The symptom score was reduced to 5.67 points after treatment.

Two weeks later: the symptoms are further relieved, and the symptoms such as nasal itching, eye itching and the like are relieved. The symptom score was reduced to 4.12 points.

After one month: the symptoms of the patient are basically disappeared, and slight nasal obstruction is occasionally caused, but normal life is not affected. The symptom score was reduced to 1.89 points.

(2) Nasal cavity examination results:

One week after treatment: the edema ratio was reduced to 56.32% and the nasal meatus visible water-like secretion ratio was reduced to 45.23%.

Two weeks after treatment: the edema ratio was further reduced to 38.90% and the nasal meatus visible water-like secretions ratio was reduced to 29.87%.

One month after treatment: the edema ratio was reduced to 10.01% and the nasal meatus visible water-like secretions ratio was reduced to 5.62%. The nasal mucosa is basically recovered to be normal, obvious congestion edema and secretion are not seen,

(3) Emotional state improvement:

After treatment, the emotion of the lady is gradually stable, the anxiety is reduced, and the life quality and the office efficiency are improved. And in the later treatment test, the influence score of the illness state on the psychological state is 44.56 points, and the influence score of the illness state on the sleep quality is 75.34 points.

6. Conclusion(s)

The case report details the change of the illness state of a patient with severe allergic rhinitis for one year after the treatment by using the traditional Chinese medicine composition. After one month of treatment, the symptoms of the patients are basically disappeared, and the quality of life is obviously improved. This result demonstrates the remarkable therapeutic effect of the Chinese medicinal composition of the present invention in treating allergic rhinitis, and particularly, is excellent in relieving symptoms, improving mental state and improving sleep quality.

Finally, it should be noted that the foregoing description is only a preferred embodiment of the present invention, and the present invention is not limited to the above-mentioned embodiment, but may be modified or some of the technical features thereof may be replaced by other technical solutions described in the foregoing embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for treating allergic rhinitis is characterized in that: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-12 parts of prepared aconite root, 12-18 parts of astragalus root, 12-18 parts of pilose asiabell root, 8-12 parts of perilla leaf, 8-12 parts of notopterygium root, 8-12 parts of paniculate swallowwort root, 8-12 parts of white mulberry root-bark, 9-12 parts of mung bean sprout, 5-7 parts of red paeony root, 5-7 parts of bitter orange, 5-7 parts of bupleurum root, 8-12 parts of albizia flower, 8-12 parts of wild jujube seed and 8-10 parts of liquorice.

2. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 1, wherein: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 8-10 parts of prepared aconite root, 12-15 parts of astragalus root, 12-15 parts of pilose asiabell root, 8-10 parts of perilla leaf, 8-10 parts of notopterygium root, 8-10 parts of paniculate swallowwort root, 8-10 parts of white mulberry root-bark, 9-11 parts of red bean sprout, 5-6 parts of red paeony root, 5-6 parts of bitter orange, 5-6 parts of bupleurum root, 8-10 parts of albizia flower, 8-10 parts of wild jujube seed and 8-9 parts of liquorice.

3. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 1, wherein: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-12 parts of prepared aconite root, 15-18 parts of astragalus root, 15-18 parts of pilose asiabell root, 10-12 parts of perilla leaf, 10-12 parts of notopterygium root, 10-12 parts of paniculate swallowwort root, 10-12 parts of white mulberry root-bark, 11-12 parts of mung bean sprout, 6-7 parts of red paeony root, 6-7 parts of bitter orange, 6-7 parts of bupleurum root, 10-12 parts of albizia flower, 10-12 parts of wild jujube seed and 9-10 parts of liquorice.

4. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 1, wherein: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10 parts of prepared aconite root, 15 parts of astragalus root, 15 parts of pilose asiabell root, 10 parts of perilla leaf, 10 parts of notopterygium root, 10 parts of paniculate swallowwort root, 10 parts of white mulberry root-bark, 11 parts of mung bean sprout, 6 parts of red paeony root, 6 parts of bitter orange, 6 parts of radix bupleuri, 10 parts of albizia flower, 10 parts of wild jujube seed and 9 parts of liquorice.

5. The traditional Chinese medicine composition for treating allergic rhinitis according to claim 1, wherein: the mass requirements of the raw materials are as follows:

preparing radix aconiti lateralis preparata: stewing the attachment piece with ginger;

radix astragali: cleaning or cutting, wherein the content of effective components of Astragaloside IV and calycosin is not less than 2 times of pharmacopoeia standard;

Notopterygium root: cutting to obtain volatile oil with content of not less than 3.0%;

radix paeoniae rubra: cutting, wherein paeoniflorin content is not less than 2.5%;

fructus Aurantii: honey-fried, and the naringin content is not less than 8.0%;

Bupleurum root: cutting, wherein the purity is not lower than 97%;

Semen Ziziphi Spinosae: the content of spinosin is not less than 0.10%;

Licorice root: cutting to obtain glycyrrhizic acid content of not less than 2.5%.

6. A method for preparing a traditional Chinese medicine composition for treating allergic rhinitis according to any one of claims 1 to 5, which is characterized in that: the method comprises the following steps: mixing all the raw materials according to the parts by weight, adding water for decoction, filtering and concentrating after the decoction is finished.

7. The method for preparing the traditional Chinese medicine composition for treating allergic rhinitis according to claim 6, which is characterized in that: the method comprises the following steps:

8. The method for preparing the traditional Chinese medicine composition for treating allergic rhinitis according to claim 7, which is characterized in that: in the step S1, the water consumption for soaking the prepared aconite is 150-250 parts, and the water consumption for soaking other raw material medicines except the prepared aconite is 800-1000 parts; in the step S2, the first decoction time is 30-60min, and the second decoction time is 35-45min.

9. A pharmaceutical formulation characterized in that: a Chinese medicinal composition comprising the composition of any one of claims 1-5 for treating allergic rhinitis.

10. Use of a Chinese medicinal composition according to any one of claims 1-5 in the preparation of a medicament for the treatment of allergic rhinitis.