CN117898395B - Fermentation composition and its application in preparing products with laxative effect - Google Patents

Abstract

The present invention relates to the technical field of health food, in particular to a fermented composition and its application in preparing a product with the effect of moistening the intestine and relieving constipation. The composition of the present invention is prepared by fermenting peach blossom, rose flower, bitter almond, red bean, polished rice and oat rice with Hericium erinaceus as raw materials. The composition can significantly improve the intestinal ink propulsion rate, significantly shorten the time of the first black stool, and significantly increase the number of black stool grains discharged in 6 hours and the weight of black stool discharged in 6 hours. The laxative effect is significantly better than that of Hericium erinaceus fermented composition 2 (compared with the raw materials of the present invention, peach blossom and bitter almond are lacking) and composition 3 (compared with the composition of the present invention, no fermentation) without Hericium erinaceus fermentation, indicating that each component in the composition of the present invention has a significant synergistic effect and is indispensable.

Description

Fermentation composition and its application in preparing products with laxative effect

Technical Field

The invention relates to the technical field of health food, in particular to a fermentation composition and application thereof in preparing a product having the function of moistening intestines and relieving constipation.

Background technique

With the rapid development of social economy, the pace of life in the whole society is gradually accelerating, and people are under increasing work pressure. The daily diet and work and rest time of office workers are extremely irregular, which leads to the increasingly common sub-health phenomena such as gastrointestinal dysfunction, especially functional constipation, which seriously affects people's quality of life. Constipation refers to the disease and syndrome of feces staying in the intestine for too long, prolonging the defecation cycle, or the cycle is not long, but the feces are dry and hard, and it is difficult to discharge, or the feces are not hard, and although there is a desire to defecate, the defecation is not smooth. Long-term dryness may be accompanied by symptoms such as abdominal distension, dry mouth, fatigue, and fatigue. It may also cause hemorrhoids, anal fissures, intestinal bleeding, polyps, and severe rectal tumors. Difficult defecation can also aggravate other diseases, such as hypertension, acute myocardial infarction, cerebrovascular accident, etc. At present, the main drugs used in Western medicine to treat constipation are external drainage drugs, and enema is often used. Enema is a high-osmotic pressure glycerin, which will penetrate the water in the intestinal wall into the intestinal cavity, and glycerin has a lubricating effect, so it can relieve constipation. However, its side effect is that it can cause dryness of the intestinal wall, and frequent use can cause habitual constipation. Traditional Chinese medicine preparations for treating constipation on the market often contain laxative drugs such as rhubarb, senna leaves, and cassia seeds. Since such drugs contain a variety of anthraquinone glycosides and tannins, anthraquinone glycosides have a laxative effect, and tannins have astringent and antidiarrheal effects, long-term use can cause secondary constipation. At the same time, such drugs are bitter and cold, and long-term use can easily damage the spleen and stomach, leading to more side effects, and even diarrhea, abdominal pain, intestinal diseases, etc. Therefore, there is an urgent need to provide a composition that can effectively improve the symptoms of constipation, does not cause dependence, and has few side effects.

Summary of the invention

In view of this, the present invention provides a fermentation composition and its use in preparing a product with laxative effect. The fermentation composition has significant laxative effect, can significantly improve constipation symptoms, can defecate normally after taking it for a short time, will not cause dependence, and has little side effects.

In order to achieve the above-mentioned invention object, the present invention provides the following technical solutions:

The fermented composition is prepared by fermenting raw materials including peach blossoms, rose blossoms, bitter almonds, adzuki beans, polished rice and oatmeal with edible fungi.

According to the medical theory and clinical experience of TCM clinical treatment of constipation, the present invention combines peach blossom, rose flower, bitter almond, red bean, polished rice and oat rice with laxative effect, and inoculates Hericium erinaceus with digestive function for fermentation to obtain a fermentation composition. The fermentation composition improves the balance of intestinal flora and achieves the effect of moistening the intestine and promoting laxative effect.

Peach blossom is bitter and flat in nature. It has the effects of purging and relieving constipation, promoting diuresis and reducing swelling. It is used for edema, ascites, constipation and dryness. "Shenghui Fang" records that it is used for dry feces blocking the intestines, distension and pain.

Rose is the dried flower bud of the plant Rosa rugosa Thunb. of the Rosaceae family. It is sweet, slightly bitter, and warm in nature. It enters the liver and spleen meridians. It has the effects of strengthening the liver and stomach, promoting blood circulation and regulating menstruation, moistening the intestines and relieving constipation, relieving depression and calming the mind. It can soothe emotions, balance endocrine, replenish blood and qi, and treat constipation.

Bitter almonds are the dried mature seeds of Prunus armeniaca L.var.ansu Maxim., Prunus sibirica L., Prunus mandshurica (Maxim.) Koehne or Prunus armeniaca L. of the Rosaceae family. They have the effects of lowering qi, relieving cough and asthma, moistening the intestines and relieving constipation. They are used for cough and asthma, chest fullness and phlegm, blood deficiency and body fluid dryness, and dry intestines and constipation.

Adzuki bean is the dried mature seed of Phaseolus calcaratus Roxb. or Phaseolus angularis Wight of the Leguminosae family. It tastes sweet and is neutral in nature. It can invigorate the spleen and eliminate dampness, disperse blood, and detoxify.

Japonica rice is the seed of the grass herb rice (japonica rice) Oryza sativa L. In the "Qianjin Fang·Shizhi", Sun Simiao, a medical scientist in the Tang Dynasty, emphasized that japonica rice can nourish the stomach and grow muscles; the "Shijian Bencao" written by Chai Yi in the Qing Dynasty also believed that japonica rice has good effects of nourishing the spleen and stomach, nourishing the five internal organs, and strengthening the strength. Japonica rice tastes sweet and has a neutral nature. It can benefit the spleen and stomach and eliminate thirst. Modern research has shown that the crude fiber molecules in the bran layer of japonica rice help gastrointestinal motility and have a good effect on stomach diseases, constipation, hemorrhoids, etc.; japonica rice can improve the body's immune function and promote blood circulation, thereby reducing the chance of high blood pressure. In the present invention, the japonica rice is mainly produced in Northeast China, also known as Northeast rice.

Oat rice is the seed of the grass plant oat (Latin name: Avena sativa L.). It is called brome and wild wheat in the Compendium of Materia Medica. It is sweet and mild in nature. It can nourish the spleen and heart and stop sweating. It has high nutritional value. The water-soluble dietary fiber in oat is 4.7 times and 7.7 times that of wheat and corn respectively. The fat content is 4 times that of rice, and the content of 8 kinds of amino acids and vitamin E required by the human body is also higher than that of rice and white flour. Nutritionists have found that oat is also an ideal food for preventing atherosclerosis, hypertension and coronary heart disease. It is rich in linoleic acid, accounting for 35% to 52% of all unsaturated fatty acids. It has auxiliary therapeutic effects on diabetes, fatty liver, constipation, edema, cardiovascular and cerebrovascular diseases, etc. It is very beneficial for middle-aged and elderly people to improve their physical strength and prolong their life.

Peach blossoms and roses contain a lot of volatile oils, flavonoids, coumarin trifoliate and various vitamins and other nutrients. Bitter almonds contain oil components. The three kinds of food and medicine can stimulate gastrointestinal peristalsis, promote defecation, expel toxins from the body, relieve constipation and reduce swelling. Adzuki beans contain a lot of protein, peptides, fat and amino acids; polished rice and oatmeal contain starch, protein, fat, dietary fiber and B vitamins. The three kinds of food can benefit the spleen and stomach, eliminate dampness, eliminate thirst and prevent diseases such as diabetes, beriberi, senile plaques and constipation. Peach blossom is cold in nature and should not be taken for a long time, as it will damage the spleen and stomach; rose flower is warm in nature, and can be used with peach blossom to alleviate its bitter and cold nature; adzuki bean, polished rice, and oatmeal are sweet and neutral in nature, which can benefit the spleen and stomach. Polished rice and oatmeal can also provide carbon sources and vitamins for Hericium erinaceus, and adzuki bean provides nitrogen source for Hericium erinaceus. After the six medicinal and edible substances are combined, they are connected to Hericium erinaceus for biotransformation, producing saccharifying enzymes that can hydrolyze starch into glucose and other nutrients, which can improve the balance of intestinal flora. Therefore, the fermented product of the combination has a pleasant floral fragrance, can effectively regulate the human digestive function, and prevent and treat stubborn constipation.

The present invention uses peach blossom, rose flower, bitter almond, polished rice, oat rice and red bean as raw materials, and uses edible fungi (such as Hericium erinaceus) with stomachic and digestive effects for biotransformation to obtain a fermentation composition. After mice were continuously given the fermentation composition by oral gavage for one week, the effect of moistening the intestine and relieving constipation on constipation model mice was investigated. The results showed that the fermentation composition had a significant effect of moistening the intestine and relieving constipation, could significantly improve the symptoms of constipation, and normal defecation could be achieved after taking it for a short time with little side effects.

In the present invention, the edible fungi include Hericium erinaceus. The present invention has no special restrictions on the specific source of Hericium erinaceus, and any edible fungi commonly used in the art can be used. In a specific embodiment of the present invention, Hericium erinaceus is purchased from Fuzhidao (Jilin) Biotechnology Co., Ltd.

In the present invention, the polished round-grained rice is the polished round-grained rice after soaking, and the oat rice is the oat rice after soaking.

In some embodiments, the dry weight mass ratio of the peach blossom, rose flower, bitter almond, adzuki bean, polished round-grained rice and oat rice is (2-4): (2-4): (5-6): (5-6): (10-15): (68-74).

In some embodiments, the added amount of the edible fungi is 10-12% of the total weight of the peach blossoms, rose flowers, bitter almonds, red beans, polished rice and oat rice, and the specific mass percentages may be 10%, 10.5%, 11%, 11.5%, and 12%.

In some specific embodiments, the edible fungus is Hericium erinaceus, and the mass ratio of the peach blossom, rose flower, bitter almond, adzuki bean, polished rice, oatmeal and Hericium erinaceus is 3:3:5:5:10:74:10.

In some specific embodiments, the edible fungus is Hericium erinaceus, and the mass ratio of the peach blossom, rose flower, bitter almond, adzuki bean, polished rice, oatmeal and Hericium erinaceus is 4:4:6:6:12:68:10.

In some specific embodiments, the edible fungus is Hericium erinaceus, and the mass ratio of the peach blossom, rose flower, bitter almond, adzuki bean, polished rice, oatmeal and Hericium erinaceus is 2:2:6:6:15:69:12.

The present invention also provides a method for preparing the fermentation composition, comprising:

Peach blossoms, roses, bitter almonds and adzuki beans are crushed, mixed with soaked polished rice and oatmeal, sterilized, cooled to room temperature, inoculated with Hericium erinaceus and fermented;

The fermentation product is collected, dried and crushed to obtain the fermentation composition of the present invention.

In some embodiments, the soaking is soaking in water, and the soaking is to the extent of being lightly crushed by hand;

The fermentation culture temperature is 28° C.-32° C., and the culture is carried out until the mycelium is fully grown. The general culture time is 20-30 days.

In some embodiments, the drying temperature is 50°C to 75°C, specifically 50°C, 55°C, 60°C, 65°C, 70°C, or 75°C.

The present invention also provides the use of the fermentation composition or the fermentation composition prepared by the preparation method of the present invention in preparing a product having the effect of moistening the intestine and relieving constipation.

The present invention also provides a health food, comprising an effective amount of the fermentation composition of the present invention and auxiliary materials acceptable in food science.

The present invention has no special requirements for excipients acceptable in food science, and any common or commonly used types in the art can be used, such as edible flavors, sweeteners, acidulants, fillers, preservatives, etc. Those skilled in the art can add them according to actual needs.

The health food can be in any dosage form in the current health care product field, including but not limited to pills, capsules, tablets, powders, granules, oral liquids or pastes, etc.

Each dosage form can be prepared by selecting suitable acceptable excipients according to the actual needs of the dosage form, which belongs to the conventional dosage form preparation technology in the field.

The present invention uses peach blossom, rose flower, bitter almond, polished rice, oat rice and red bean as raw materials, and uses edible fungi (such as Hericium erinaceus) with stomachic and digestive effects for biotransformation to obtain a fermentation composition. The fermentation composition is healthy and nutritious, has certain health care effects, can relieve constipation through diet therapy, is safe and effective, improves people's sub-health status, and is suitable for public consumption.

Detailed ways

The present invention provides a fermentation composition and its application in the preparation of a product with laxative effect. Those skilled in the art can refer to the content of this article and appropriately improve the process parameters to achieve it. It is particularly important to point out that all similar replacements and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention. The method and application of the present invention have been described through preferred embodiments, and relevant personnel can obviously modify or appropriately change and combine the method and application of this article without departing from the content, spirit and scope of the present invention to realize and apply the technology of the present invention.

The raw materials used in the present invention are all common commercial products and can be purchased in the market.

The present invention will be further described below in conjunction with embodiments:

Example 1 Preparation of fermentation composition

Peach blossoms, roses, bitter almonds, and adzuki beans were screened, and the surface dirt and other impurities were washed with water, dried, and crushed into coarse powder. Carefully selected high-quality Northeastern rice and oatmeal were washed with water and soaked until they could be gently crushed by hand. Peach blossoms: roses: bitter almonds: adzuki beans: polished rice: oatmeal were mixed in a dry weight ratio of 3:3:5:5:10:74 and sterilized at 121°C for 50 min. After cooling to room temperature, 10% Hericium erinaceus strains were added. The mixed raw materials were placed in a sterile container and sealed. Fermented and cultured at a constant temperature of 28°C until the mycelium was fully grown, the fermentation products were collected, dried at 60°C, and crushed to obtain a fermentation composition.

Example 2 Preparation of fermentation composition

Peach blossoms, roses, bitter almonds, and adzuki beans were screened, and the surface dirt and other impurities were washed with water, dried, and crushed into coarse powder. Carefully selected high-quality Northeastern rice and oatmeal were washed with water and soaked until they could be gently crushed by hand. Peach blossoms: roses: bitter almonds: adzuki beans: polished rice: oatmeal were mixed in a dry weight ratio of 4:4:6:6:12:68 and sterilized at 126°C for 40 min. After cooling to room temperature, 10% Hericium erinaceus strains were added. The mixed raw materials were placed in a sterile container and sealed. Fermented and cultured at a constant temperature of 30°C until the mycelium was fully grown, the fermentation products were collected, dried at 70°C, and crushed to obtain a fermentation composition.

Example 3 Preparation of fermentation composition

Peach blossoms, roses, bitter almonds, and adzuki beans were screened, and the surface dirt and other impurities were washed with water, dried, and crushed into coarse powder. Carefully selected high-quality Northeastern rice and oatmeal were washed with water and soaked until they could be gently crushed by hand. Peach blossoms: roses: bitter almonds: adzuki beans: polished rice: oatmeal were mixed in a dry weight ratio of 2:2:6:6:15:69 and sterilized at 126°C for 30 min. After cooling to room temperature, 12% Hericium erinaceus strains were added. The mixed raw materials were placed in a sterile container and sealed. Fermented and cultured at a constant temperature of 32°C until the mycelium was fully grown, the fermentation product was collected, dried at 75°C, and crushed to obtain a fermentation composition.

Test Example 1: Effect of the composition on small intestinal motility in mice

1 Methods

1.1 Composition and preparation

Preparation of Composition 1: A fermentation composition was prepared according to the method of Example 1 to obtain Composition 1.

Preparation of composition 2: Rose, adzuki bean, polished rice and oatmeal are mixed in a dry weight mass ratio of rose: adzuki bean: polished rice: oatmeal of 3:5:10:74, sterilized at 121°C for 50 min, and added with 10% Hericium erinaceus strain after cooling to room temperature, and the mixed raw materials are placed in a sterile container, sealed, and cultured at a constant temperature of 28°C until the mycelium is fully grown, and the fermentation product is collected, dried at 60°C, and crushed to obtain composition 2. The Hericium erinaceus strain is the same as that in Example 1.

Preparation of composition 3: Take peach blossom, rose, bitter almond, adzuki bean, polished rice and oatmeal, mix them in a mass ratio of 3:3:5:5:10:74 of peach blossom: rose: bitter almond: adzuki bean: polished rice: oatmeal, and grind them to obtain composition 3.

1.2 Small intestinal motility test

According to the laxative function test method of the "Health Food Functional Test and Technical Evaluation Specification" (2003 Edition). The mice were divided into 5 groups, 6 in each group, and divided into 3 dosing groups: blank control group, model control group, HF1 group (composition 1, 3.32g/kgBW), HF2 group (composition 2, 3.32g/kgBW), and ZH group (composition 3, 3.32/kgBW) (equivalent to 10 times the daily dose of humans). Different concentrations of samples were prepared with distilled water every day, and the animals were gavaged at 20mL/kgBW. The blank control group and the model control group were given the same volume of distilled water. The test samples were given continuously for 7 days. After 7 days of giving the test samples, the mice in each group were fasted but not watered for 16 hours. The model control group and the three dosing groups were gavaged with compound diphenoxylate 5mg/kgBW (10mL/kgBW), and the blank control group was given distilled water. 0.5 hours after the administration of compound diphenoxylate, each administration group was gavaged with ink (containing 5% activated carbon powder and 10% gum arabic) containing the corresponding test sample, and the blank control group and the model control group were given ink. 25 minutes later, the animals were immediately killed by dislocating the cervical vertebra, the abdominal cavity was opened to separate the mesentery, and the intestinal tube from the pylorus at the upper end and the ileocecal part at the lower end was cut and placed on a tray. The small intestine was gently pulled into a straight line, and the intestinal length was measured as the "total length of the small intestine", and the length from the pylorus to the front of the ink was the "ink advancement length". The ink advancement rate was calculated according to the following formula:

1.3 Statistical methods

SPSS 18.0 software was used for statistical analysis. The differences were statistically significant when P < 0.05.

1.4 Result determination

On the premise that the model is established, when the ink propagation rate of the mice in the test sample group is significantly higher than that in the model control group, the experimental result can be determined to be positive.

2 Results

As shown in Table 1, compared with the blank control group, the ink propulsion length of the model control group was significantly shortened, and the ink propulsion rate was significantly reduced (P<0.05), indicating that the small intestinal peristalsis inhibition model was established; compared with the model control group, the ink propulsion length and propulsion rate of each drug-treated group of the test sample increased, among which the ink propulsion rate of the HF1 group was extremely significantly different from that of the model control group (P<0.01), and the ink propulsion rate of the HF2 group was significantly different from that of the model control group (P<0.05), while the ink propulsion rate and ink propulsion length of the ZH group were not significantly different from those of the model control group (P>0.05). According to the result judgment criteria, the small intestinal motility test results were judged to be positive.

Table 1: Effects of the composition on small intestinal motility

Note: Compared with the blank group, ^# indicates significant difference P<0.05, ^## indicates extremely significant difference P<0.01.

Compared with the model group, ^* indicates significant difference, P<0.05; ^** indicates extremely significant difference, P<0.01.

3 Conclusion

The mice were given oral administration once a day in the three drug-dosing groups: HF1, HF2 and ZH, with an oral administration volume of 20 mL/kg BW. The blank control group and the model control group were given the same volume of distilled water for 7 consecutive days. Under the experimental conditions, the results of the small intestinal motility test were positive.

The higher the ink propulsion rate, the better the laxative effect. Compared with the model group, the ink propulsion rates of the HF1 group and the HF2 group were significantly increased, among which the HF1 group had a very significant difference with the model group (P<0.01), and the HF2 group had a significant difference with the model group (P<0.05). However, there was no significant difference between the ZH group and the model group (P＞0.05). The results showed that the laxative effect of the HF1 group was significantly better than that of the HF2 and ZH groups.

Test Example 2: Effect of the composition on the defecation time, number of black stool particles and weight of black stool in mice

1 Methods

1.1 Preparation of composition

Preparation of composition 1: Composition 1 was obtained by the method of Example 1.

Preparation of composition 2: Rose, adzuki bean, polished rice and oatmeal are mixed in a dry weight mass ratio of rose: adzuki bean: polished rice: oatmeal of 3:5:10:74, sterilized at 121°C for 50 min, and added with 10% Hericium erinaceus strain after cooling to room temperature, and the mixed raw materials are placed in a sterile container, sealed, and cultured at a constant temperature of 28°C until the mycelium is fully grown, and the fermentation product is collected, dried at 60°C, and crushed to obtain composition 2. The Hericium erinaceus strain is the same as that in Example 1.

Preparation of composition 3: Take peach blossom, rose, bitter almond, adzuki bean, polished rice and oatmeal, mix them in a mass ratio of 3:3:5:5:10:74 of peach blossom: rose: bitter almond: adzuki bean: polished rice: oatmeal, and grind them to obtain composition 3.

1.2 Measurement of defecation time, number of black stool particles, and weight of black stool

The mice were divided into 5 groups, 6 mice in each group, and divided into 3 dosing groups: blank control group, model control group, HF1 group (composition 1, 3.32g/kgBW), HF2 group (composition 2, 3.32g/kgBW), and ZH group (composition 3, 3.32/kgBW) (equivalent to 10 times the daily dose of humans). Different concentrations of samples were prepared with distilled water every day and administered to animals by gavage at 20mL/kgBW. The blank control group and the model control group were given the same volume of distilled water. The test samples were administered continuously for 7 days. After 7 days of administration of the test samples, the mice in each group were fasted but not watered for 16 hours. The blank control group was given distilled water, and the model control group and the three dosing groups were given compound diphenoxylate 10mg/kgBW (10mL/kgBW) by gavage. 0.5h after compound diphenoxylate was administered, each administration group was gavaged with ink (containing 5% activated carbon powder and 10% gum arabic) containing the corresponding test sample, and the blank control group and model control group were given ink. The animals were housed in single cages and fed with normal water. From the beginning of ink administration, the time of the first black stool of each animal, the number of black stools within 6h and the weight were recorded.

1.3 Statistical methods

SPSS 18.0 software was used for statistical analysis. The differences were statistically significant when P < 0.05.

1.4 Result determination

Under the premise of establishing the small intestinal constipation model, if the time of the first black stool of the mice in the test sample group is significantly shorter than that of the model control group, the result of this indicator can be determined to be positive. If the number of black stools discharged within 6 hours is significantly higher than that of the model control group, the result of this indicator can be determined to be positive. If the weight of black stools discharged within 6 hours is significantly higher than that of the model control group, the result of this indicator can be determined to be positive.

2 Results

As shown in Table 2, compared with the blank control group, the time of the first black stool in the model control group was significantly prolonged (P<0.05), and the number and weight of black stool particles were extremely significantly reduced (P<0.01), indicating that the small intestinal constipation model was established. Compared with the model control group, each drug-treated group could significantly shorten the time of the first black stool and increase the number and weight of black stool particles within 6 hours. Among them, the time of the first black stool, the number and weight of black stool particles within 6 hours in the HF1 group were significantly different from those in the model control group (P<0.01), the number and weight of black stool particles within 6 hours in the HF2 group were significantly different from those in the model control group (P<0.05), and only the time of the first black stool in the ZH group was significantly different from that in the model control group (P<0.05). According to the result judgment criteria, the results of the three indicators of the time of the first black stool, the number of black stool particles and the weight of black stool were all positive.

Table 2: Effects of the composition on the time to first black stool, number of black stools and weight of black stools ( ）

Note: Compared with the blank group, ^# indicates significant difference P<0.05, ^## indicates extremely significant difference P<0.01.

Compared with the model group, ^* indicates significant difference, P<0.05; ^** indicates extremely significant difference, P<0.01.

3 Conclusion

The three groups of HF1, HF2 and ZH were given to mice by gavage once a day, with a gavage volume of 20 mL/kg BW, and the blank control group and the model control group were given the same volume of distilled water for 7 consecutive days. Under the experimental conditions, the result of the first black stool time was positive; the result of the number of black stools was positive; the result of the weight of black stools was positive.

As shown in Table 2, the composition 1 (HF1 group) of the present invention can significantly shorten the time of the first black stool, and significantly increase the number of black stool particles and the weight of black stool particles in 6 hours, which are significantly different from the model group (P<0.01). However, the composition 2 (HF1 group) fermented by Hericium erinaceus lacking peach blossom and bitter almonds, compared with the model group, only the number of black stool particles and the weight of black stool particles in 6 hours were significantly increased (P<0.05), and there was no significant difference in the time of the first black stool (P>0.05). Compared with the model group, the composition 3 (ZH group) can significantly shorten the time of the first black stool (P<0.05), and the number of black stool particles and the weight of black stool particles in 6 hours are improved, but there is no significant difference (P>0.05). It shows that the laxative effect of the composition 1 of the present invention is significantly better than that of the compositions 2 and 3.

From the above results, it can be seen that the composition of the present invention, which is prepared by fermenting peach blossom, rose flower, bitter almond, red bean, polished rice and oatmeal with Hericium erinaceus, can significantly improve the intestinal ink propulsion rate, significantly shorten the time of the first black stool, and significantly increase the number of black stools discharged in 6 hours and the weight of black stools discharged in 6 hours. It shows that the laxative effect of the composition of the present invention is significantly better than that of Hericium erinaceus fermented composition 2 (compared with the raw materials of the present invention, peach blossom and bitter almond are lacking) and composition 3 (compared with the composition of the present invention, no fermentation) without Hericium erinaceus fermentation, indicating that the components in the composition of the present invention are reasonably matched and produce a good synergistic effect, and none of them is indispensable.

The above are only preferred embodiments of the present invention. It should be pointed out that, for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims (7)

1. A fermented composition, characterized in that it is made from raw materials of peach blossom, rose, bitter almond, adzuki bean, polished rice and oatmeal fermented by edible fungi; The fermentation composition is characterized in that the edible fungus is Hericium erinaceus; The dry weight mass ratio of the peach blossom, rose flower, bitter almond, adzuki bean, polished round-grained rice and oatmeal is (2-4): (2-4): (5-6): (5-6): (10-15): (68-74); The added amount of the edible fungi is 10-12% of the total weight of the peach blossoms, rose blossoms, bitter almonds, red beans, polished rice and oatmeal. 2. The fermented composition according to claim 1, characterized in that the polished round-grained rice is soaked polished round-grained rice, and the oatmeal is soaked oatmeal. 3. The fermentation composition according to any one of claims 1 to 2, characterized in that the edible fungus is Hericium erinaceus, and the dry weight mass ratio of the peach blossom, rose flower, bitter almond, adzuki bean, polished rice, oat rice and Hericium erinaceus is 3:3:5:5:10:74:10, 4:4:6:6:12:68:10 or 2:2:6:6:15:69:12. 4. The method for preparing the fermentation composition according to any one of claims 1 to 3, characterized in that it comprises: Peach blossoms, roses, bitter almonds and adzuki beans are crushed, mixed with soaked polished rice and oatmeal, sterilized, cooled to room temperature, inoculated with Hericium erinaceus and fermented; The fermented product is collected, dried and crushed to obtain a fermentation composition. 5. The preparation method according to claim 4, characterized in that the soaking is soaking in water, and the soaking is to the extent of being lightly crushed by hand; The fermentation temperature is 28°C-32°C and the fermentation time is 20-30 days; The drying temperature is 50°C to 75°C. 6. Use of the fermentation composition according to any one of claims 1 to 3 or the fermentation composition obtained by the preparation method according to claim 4 or 5 in preparing a product having the effect of moistening the intestine and relieving constipation. 7. A health food, characterized in that it comprises the fermentation composition according to any one of claims 1 to 3 and an auxiliary material acceptable in food science.