CN116747154B - A cerium oxide-based sunscreen material that can resist blue light and its preparation method - Google Patents

Abstract

The invention discloses a cerium oxide-based sun-screening material capable of resisting blue light and a preparation method thereof, wherein the sun-screening material comprises the following components: polyethyleneimine, triethylamine, cerium nitrate hexahydrate, L-ascorbic acid and silver nitrate. The sun-screening material disclosed by the invention has excellent ultraviolet resistance, blue light resistance, bacteriostasis and good biocompatibility. The invention solves the problems of light pollution related to light aging and the like from ultraviolet light and short-wave blue light bands, and the synthesis method adopts simple chemical precipitation.

Description

A cerium oxide-based sunscreen material that can resist blue light and its preparation method

Technical field

The invention relates to the technical field of new materials, and in particular to a cerium oxide-based sunscreen material that can resist blue light and a preparation method thereof.

Background technique

Shortwave blue light is a visible light wave in the blue light region, located at 400-450 nm. It mainly comes from natural light and electronic display screens. Due to the radiation from electronic display screens, various degrees of eye diseases are caused, such as vision loss, cataracts, blindness, etc. When testing electronic screens, scientific researchers found that the light emitted by the screen contains a large number of irregularities. High-energy short-wave blue light with a short wavelength and strong penetrating ability can trigger oxidative stress reactions and induce cell damage; "light" also has a cumulative effect. Long-term contact or exposure to short-wave blue light will reduce cell activity. Change the physiological morphology of normal cells. Therefore, the physiological damage caused by short-wave blue light is no less than that of ultraviolet light.

However, the current anti-blue light technologies in the field of cosmetics mainly focus on relieving pigmentation, delaying skin aging, and cell pathways, and there is little research on the development of physical absorption of radiation; at the same time, existing physical sunscreens and chemical sunscreens cannot Filtering and shielding short-wave blue light, physical sunscreen materials such as titanium dioxide and zinc oxide are commonly used today in cosmetics use scenarios, often making the skin false white and easily causing dry and peeling skin; zinc oxide also has similar false whitening properties and is sticky when used, and due to the two It has strong photocatalytic activity and easily generates free radicals when used, which accelerates cell aging.

In view of this, it is urgent to develop new composite materials based on cerium oxide and other materials to solve the short-wave blue light hazards faced by people.

Contents of the invention

The object of the present invention is to provide a cerium oxide-based sunscreen material that can resist blue light in view of the above-mentioned existing deficiencies. It has the functions of resisting blue light, shielding ultraviolet rays, and being antibacterial. It can be used as an oxide-based composite material UV and blue light shielding agent and a new type of sunscreen material. Physical sunscreen.

Another object of the present invention is to provide a method for preparing the aforementioned cerium oxide-based sunscreen material that can resist blue light.

The technical solutions adopted by the present invention to achieve the above objects are:

A cerium oxide-based sunscreen material that can resist blue light, which includes the following components: polyethyleneimine (PEI), triethylamine (TEA), cerium nitrate hexahydrate (Ce(NO ₃ ) ₃ ·6H ₂ O ), L-ascorbic acid (L-AC), silver nitrate (SN); the molar ratio of the polyethyleneimine PEI and cerium nitrate hexahydrate (Ce(NO3)3·6H2O) is 2~4:1~10; The molar ratio of the triethylamine TEA and the cerium nitrate hexahydrate (Ce(NO3)3·6H2O) is 5~20:1~200; the molar ratio of the L-ascorbic acid (L-AC) and the cerium nitrate hexahydrate (Ce( The molar ratio of NO3)3·6H2O) is 1~2:120~600; the molar ratio of the silver nitrate (SN) and hexahydrate cerium nitrate (Ce(NO3)3·6H2O) is 1~2:100~250 .

The present invention uses triethylamine (TEA) to provide an alkaline environment to control the pH, further utilizes cerium nitrate hexahydrate (Ce(NO ₃ ) ₃ ·6H ₂ O) to react, polyethyleneimine (PEI) as a template, and utilizes its adhesive The adhesion makes the surface of cerium oxide (CeO ₂ ) rich in amine groups, resulting in the first-generation modified cerium oxide (CeO ₂ -PEI) with certain resistance to blue light; using silver nitrate (NS) as the silver source, L-ascorbic acid (L- AC) is used as a reducing agent to further reduce silver nitrate (NS) and complex with the surface amine group of modified cerium oxide (CeO ₂ -PEI) to prepare a cerium oxide-based sunscreen material that can resist blue light.

The preparation method of the above-mentioned cerium oxide-based sunscreen material capable of resisting blue light according to the present invention includes the following steps:

S1, dissolve cerium nitrate hexahydrate in absolute ethanol, stir to fully dissolve, and obtain solution A;

S2, dissolve polyethyleneimine in absolute ethanol, stir to fully dissolve, and obtain solution B;

S3, slowly add solution B to solution A until a large amount of white floc appears, add triethylamine, react for a certain time t1, add pure water after water cooling for a hydrolysis reaction, continue to cool for a certain period of time t2, and then react at room temperature for a certain time At time t3, suspension C is obtained;

S4, wash the suspension C with pure water until neutral, then further centrifuge and wash with absolute ethanol and pure water, dry and grind to obtain solid powder E;

S5, ultrasonically disperse the solid powder E in pure water, and drop in 2 V/V% ammonia water to obtain a turbid liquid F;

S6, add the silver ammonia solution H to the turbid liquid F, protect it from light, react for a certain time t4, add L-ascorbic acid aqueous solution G under high-speed stirring, change the rotation speed and react at room temperature for a certain time t5 to obtain the turbid liquid I;

S7, filter the turbid liquid I to obtain a gray-brown precipitate, wash it with absolute ethanol and pure water, and dry it to obtain a gray-brown powder, that is, a cerium oxide-based sunscreen material that can resist blue light is obtained.

Preferably, the concentration of solution A is 30 W/V%-50 W/V%, and the added amount of absolute ethanol is 15 mL.

Preferably, the concentration of solution B is 2.5 W/V%-10 W/V%, and the added amount of absolute ethanol is 10 mL.

Preferably, the weighing amount of triethylamine TEA in step S3 is 5-15g.

Preferably, the reaction time t ₁ in step S3 is 20-60 min, preferably 350 ml of pure water is added, the continuous cooling time t ₂ is 1-15 min, and the reaction time t ₃ at room temperature is 1-4 h.

Preferably, the concentration of solid powder E in step S5 is 1-10 W/V%, and 10 mL of pure water is preferably added.

Preferably, the step S6 also includes: dissolving L-ascorbic acid in pure water, stirring thoroughly to obtain L-ascorbic acid aqueous solution G, the concentration of L-ascorbic acid aqueous solution is 2-5 W/V%, preferably pure The amount of water added is 0.4 mL.

Preferably, the step S6 also includes: dissolving silver nitrate in pure water, stirring thoroughly, and dripping 2 V/V% ammonia water to obtain a silver ammonia solution H. The concentration of the silver ammonia solution H is 0.1-0.5 W/V. %, preferably the added amount of pure water is 5 mL.

Preferably, the reaction time t ₄ in step S6 is 10-30 min, the high-speed stirring is at a rotation speed of 1000-2000 rad/min, the duration is 1-5 min, and the reaction time t at room temperature is changed to 400-600 rad/min. ₅ is 2-10 h.

Preferably, the drying conditions in step S4 and step S7 are both drying at 95-115°C for 1-3 hours.

The present invention uses a certain amount of polyethyleneimine (PEI) as a template agent to modify the surface of cerium oxide CeO _2. The surface of the modified cerium oxide CeO ₂ -PEI contains a variety of amine groups, and these amine groups can effectively interact with silver. Particle complexation, in addition, the N atoms in the functional group structure have strong electron donating ability, so that after silver is loaded, the lone pair of electrons can be transferred to the nanosilver surface through the interaction of N atoms, thus extending the length of the composite material (Ag NPs@CeO ₂ -PEI) service life.

The polyethylenimine in the present invention is a high adhesion, high adsorption, degradable molecular polymer with good biocompatibility and cytotoxicity, and the loaded nanosilver has good biocompatibility. Dendritic polyethyleneimine (PEI) is a highly adhesive and highly absorbent polymer rich in primary, secondary and tertiary amine groups, and has good biocompatibility and water solubility.

The present invention utilizes the unique 4F ¹ electronic structure of cerium oxide CeO ₂ so that its radiation has spectral selectivity, so cerium oxide can effectively shield the visible to infrared bands.

The present invention uses L-ascorbic acid (L-AC) as a reducing agent to reduce silver nitrate (NS) to prepare nanosilver, which is assembled and attached to the surface of the modified precursor cerium oxide (CeO ₂ -PEI), so that the nanosilver is finally prepared. Cerium oxide (Ag NPs@CeO ₂ -PEI) has the optical and antibacterial performance characteristics of nanosilver.

The present invention not only modifies the surface of cerium oxide CeO ₂ , but also uses silver nitrate for doping, so that the silver particles in the solution are evenly loaded with the precursor cerium oxide CeO ₂ -PEI surface in the form of chemical bonds, and then pass through a certain concentration of L- Ascorbic acid performs reduction control and promotes the growth of silver particles on its surface, so that nanosilver is evenly and successfully loaded on the surface of the precursor cerium oxide CeO ₂ -PEI, imparting optical and antibacterial properties, and producing a cerium oxide-based sunscreen material that can resist blue light ( Ag NPs@CeO ₂ -PEI).

Compared with the prior art, the present invention has the following beneficial effects:

1. The cerium oxide-based sunscreen material of the present invention that can resist blue light adopts a simple and convenient chemical precipitation method, which is simple, controllable and gentle to operate. It uses polyethyleneimine to construct the cerium oxide surface so that the surface is rich in various The amine group can effectively complex with metal elements (such as gold, silver, copper, zinc, etc.) in the form of chemical bonds, giving it the ability to donate electrons to extend the cycle life. It can be used as an oxide-based composite material for blue light, ultraviolet Shielding agents and new physical sunscreen agents have excellent UV resistance, blue light resistance, bacteriostasis and good biocompatibility. They have excellent comprehensive performance, low cost and a wide range of applications.

2. The cerium oxide-based sunscreen material of the present invention that can resist blue light selects nanosilver as the doping metal element, giving full play to the UV characteristic peak of nanosilver itself around its 400nm light wave, achieving the advantages of traditional cerium oxide in the ultraviolet light wave region. At the same time of photoprotection, it greatly increases the comprehensive performance against blue light. When the concentration is 0.2mg.mL ^-1 , the average transmittance of short-wave blue light in the wavelength range of 400-450nm is 0.24%, and the ultraviolet absorbance in the UVA and UVB bands of 280-400nm is The average is 2.17, and the highest absorption peak absorbance is about 2.34.

3. The present invention solves the problem of harm caused by short-wave blue light to the skin, eyes, etc., greatly solves the defect of existing physical sunscreen materials that cannot shield the photo-aging caused by short-wave blue light due to the limited shielding wavelength, and also brings into play the advantages of nanotechnology. The antibacterial property of silver itself reduces the use of preservatives in related products. In the 1.2% (W/V) system, the sterilization rate reaches 82.05% against Gram-positive bacteria, and it has obvious inhibitory effects in the antibacterial test. Bacterial effect.

The above is an overview of the technical solution of the invention. The invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

Description of the drawings

Figure 1 is a schematic diagram of the FTIR infrared spectrum of cerium oxide (CeO ₂ ) and surface-modified cerium oxide (CeO ₂ -PEI) in the embodiment;

Figure 2 is an X-ray diffraction diagram of the surface-modified cerium oxide (CeO ₂ -PEI) of the embodiment;

Figure 3 is the X-ray energy spectrum of the cerium oxide-based sunscreen material (Ag NPs@CeO ₂ -PEI) that can resist blue light according to the embodiment;

Figure 4 is a schematic diagram of the relationship between cerium oxide modified with different amounts of polyethyleneimine (PEI) and UV absorbance in the embodiment;

Figure 5 is a schematic diagram of the relationship between the cerium oxide-based sunscreen material (Ag NPs@CeO ₂ -PEI) prepared by using different amounts of L-ascorbic acid (L-AC) and capable of resisting blue light and ultraviolet absorbance in the embodiment;

Figure 6 is a schematic diagram showing the use of the cerium oxide-based sunscreen material (Ag NPs@CeO ₂ -PEI) that can resist blue light as a coating for visual blue light protection according to the embodiment;

Figure 7 is a schematic diagram comparing the bactericidal effects of cerium oxide-based sunscreen materials (Ag NPs@CeO ₂ -PEI), CeO ₂ -PEI and untreated cerium oxide on Gram-positive bacteria according to the embodiment;

Figure 8 is a schematic diagram comparing the antibacterial effects on Gram-positive bacteria of the cerium oxide-based sunscreen material (Ag NPs@CeO ₂ -PEI), CeO ₂ -PEI and untreated cerium oxide according to the embodiment;

Figure 9 is a schematic diagram of the centrifugal stability test of a sunscreen product prepared by adding the cerium oxide-based sunscreen material (Ag NPs@CeO ₂ -PEI) that can resist blue light in the cosmetic formula according to the embodiment;

Figure 10 is a SEM scanning electron microscope diagram of the cerium oxide-based sunscreen material (Ag NPs@CeO ₂ -PEI) that can resist blue light according to the embodiment.

Detailed ways

In order to make the purpose, technical solutions and advantages of the present invention clearer, detailed descriptions are given below in conjunction with examples. It should be understood that the specific embodiments described here are only used to explain the present invention and are not intended to limit the present invention.

Example 1

This embodiment provides a cerium oxide-based sunscreen material that can resist blue light, which is prepared by a preparation method including the following steps:

S1, dissolve 5g of cerium nitrate hexahydrate in 15ml of absolute ethanol, stir to fully dissolve, and obtain solution A;

S2, dissolve 0.25g polyethyleneimine in 10ml absolute ethanol, stir to fully dissolve, and obtain solution B;

S3, slowly add solution B to solution A until a large amount of white floc appears, add 9.1711g triethylamine, react for a certain time t ₁ , which is 40 minutes, add 350ml pure water through water cooling, and continue to cool for a certain time t ₂ , which is 5 minutes. , and then perform a hydrolysis reaction at room temperature for a certain time t ₃ , that is, 1 hour, to obtain suspension C;

S4, wash the suspension C with pure water until neutral, then further centrifuge and wash 3 times with absolute ethanol and pure water, dry at 105°C for 2 hours, and grind to obtain solid powder E;

S5, ultrasonically disperse 0.3g solid powder E in 10ml pure water, add 5-6 drops of 2 V/V% ammonia water to obtain turbid liquid F;

S6, add 5ml of 3mg/ml silver ammonia solution H into the turbid solution F, protect from light, react for a certain time t ₄ , that is, 15 minutes, quickly add 0.1mol/l L-ascorbic acid aqueous solution G 0.4ml under high-speed stirring at 1200rad/min , change the rotation speed to 540rad/min and react at room temperature for a certain time t ₅ , that is, 3 hours to obtain turbid liquid I;

S7, filter the turbid liquid I to obtain a gray-brown precipitate, wash it three times with absolute ethanol and pure water, and dry it at 105°C for 2 hours to obtain a gray-brown powder (Ag NPs@CeO ₂ -PEI), that is, oxidized Cerium-based sunscreen material that blocks blue light.

As can be seen from Figure 1, the broad peaks of CeO ₂ -PEI at 3500-3000 cm ^-1 are attributed to the primary amine bonds in PEI. The broad peaks in this range indicate that CeO ₂ -PEI not only contains associated NH ₂ structures, but also NH Structure; the absorption peak at 1600cm ^-1 is the NH bending vibration peak of primary and secondary amines; the 1140cm ^-1 and 1100cm ^-1 are the CN stretching vibration peaks of primary and secondary amines, and the absorption peak at 1050cm ^-1 It shows that there is a tertiary amine structure in CeO ₂ -PEI. The infrared spectrum phenomenon shows that the surface of CeO ₂ is rich in PEI polymer, confirming the existence of PEI.

As can be seen from Figure 2, the characteristic peaks of CeO ₂ -PEI in X-ray diffraction (XRD) are reduced by half. Compared with the cerium oxide PDF#43-1002 standard card, (111), (220), (311), (331) Refractive crystal plane. Combined with the infrared spectrum, it can be seen that the unique refraction angle of the cerium oxide surface changes due to the rich polyethyleneimine on the surface, which further confirms that polyethyleneimine successfully exists on the cerium oxide surface.

As can be seen from Figure 3, in the X-ray energy spectrum (EDS) of Ag NPs@CeO ₂ -PEI, the characteristic peak of silver element appears, proving that CeO ₂ -PEI successfully loaded nanosilver through the amine group.

Example 2

This embodiment provides a cerium oxide-based sunscreen material that can resist blue light, which is prepared by a preparation method including the following steps. Compared with Example 1, the preparation method changes the concentration of polyethylenimine (PEI). The specific steps are: as follows:

Dissolve 0.50g polyethyleneimine (PEI) in 10mL absolute ethanol, stir to fully dissolve, and obtain solution B;

As can be seen from Figure 4, the relationship between the UV absorbance of CeO2-PEI obtained after modification of polyethyleneimine PEI with different concentrations is shown. Five sets of experiments were set up. The concentrations of polyethyleneimine used were 2.50%, 5.00%, and 7.50% respectively. ,10.00%. The UV spectra are all measured at the same concentration (0.2 mg∙mL ^-1 ). It can be seen from the figure that as the amount of PEI increases, the absorption of 450nm short-wave blue light shows a trend of first decreasing and then increasing, while in UVA In the UVB range, the absorption trend first increases and then decreases, showing good anti-ultraviolet and blue light properties.

Example 3

This embodiment provides a cerium oxide-based sunscreen material that can resist blue light, which is prepared by a preparation method including the following steps. Compared with Example 1, the preparation method changes the concentration of L-ascorbic acid (L-AC), specifically Proceed as follows:

S5, ultrasonically disperse 0.3g solid powder E in 10ml pure water, add 5-6 drops of 2 V/V% ammonia water to obtain turbid liquid F;

S6, add 5ml of 3mg/ml silver ammonia solution H into the turbid solution F, protect from light, react for a certain time t ₄ , that is, 15 minutes, quickly add 0.1mol/l L-ascorbic acid aqueous solution G 0.5ml under high-speed stirring at 1200rad/min , change the rotation speed to 540rad/min and react at room temperature for a certain time t ₅ , that is, 3 hours to obtain turbid liquid I;

S7, filter the turbid liquid I to obtain a gray-brown precipitate, wash it three times with absolute ethanol and pure water, and dry it at 105°C for 2 hours to obtain a gray-brown powder (Ag NPs@CeO ₂ -PEI), that is, oxidized Cerium-based sunscreen material that blocks blue light.

As can be seen from Figure 5, seven sets of experiments were set up in relation to the relationship between the UV absorbance and the different mass ratios of L-AC and CeO ₂ -PEI (PEI: 5%). The dosages of L-AC were 0.588% and 1.174% respectively. , 1.761%, 2.348%, 2.935%. The UV spectra were all measured at the same concentration (0.2 mg∙mL ^-1 ). It can be seen from the figure that the absorbance in the short-wave blue light region shows a trend of first increasing and then decreasing. When the dosage of L-AC is 2.348%, for the short-wave blue light region The absorbance is optimal, and the amount of L-AC in the experiment is 2.348%. The short-wave blue light absorbance of CeO ₂ after modification is higher than that before modification.

As can be seen from Figure 6, the Ag NPs@CeO ₂ -PEI sample prepared in Example 1 was made into a coating. The four letters "GDPU" in the figure were covered with 3 layers, 2 layers, and 1 layer respectively. And a coating of 0-layer sun protection material, using a commercially recognized anti-blue light test card to visually prove its resistance to blue light. It can be seen that the coating made of Ag NPs@CeO ₂ -PEI has excellent performance against blue light.

As can be seen from Figure 7, the Ag NPs@CeO ₂ -PEI sample prepared in Example 1, the CeO ₂ -PEI prepared in Example 2, and cerium oxide without any treatment were taken. Through sterilization experiments, it can be seen that the bactericidal performance of Ag NPs@CeO ₂ -PEI is significantly increased. 1.2% (W/V) can sterilize 82.05% of Gram-positive bacteria, and the sterilization rate is as high as 100% under the synergistic effect of light.

As can be seen from Figure 8, the Ag NPs@CeO ₂ -PEI sample prepared in Example 1, the CeO ₂ -PEI prepared in Example 2, and cerium oxide without any treatment were taken. Through the antibacterial experiment, it can be seen that the Ag NPs@CeO ₂ -PEI sample has an obvious inhibitory zone against Gram-positive bacteria after loading silver, so it has an antibacterial effect.

This bactericidal effect can directly or indirectly reduce the addition and use of some preservatives used in cosmetics, comprehensively reducing costs while improving antiseptic performance.

Example 4

Take 0.6g of the cerium oxide-based sunscreen material sample (Ag NPs@CeO2-PEI) that can resist blue light in Example 1 and use it as a 1.2% sunscreen. Refer to QB/T1857-2013 "Skin Care Cream" to test the product at 3000 rad/ min centrifugal speed, 30 min centrifugal stability test, the test results are shown in Figure 9, Ag NPs@CeO ₂ -PEI is evenly dispersed in cosmetic products, and no delamination occurs, indicating that Ag NPs@CeO ₂ -PEI has good complexation The cerium oxide-based sunscreen material sample of Example 1 that can resist blue light was observed using SEM scanning electron microscopy images. The results show that as shown in Figure 10, the overall morphology is close to spherical and has a relatively large High specific surface area, can effectively shield short-wave blue light and ultraviolet rays.

The specific implementation mode of the present invention uses polyethyleneimine (PEI), cerium nitrate hexahydrate

(Ce(NO ₃ ) ₃ ·6H ₂ O), silver nitrate (NS), triethylamine (TEA) is used to promote the precipitation reaction to obtain cerium oxide (CeO ₂ ), and dendritic polyethylenimine (PEI) is used as a template The preliminary product CeO ₂ -PEI is synthesized using L-ascorbic acid (L-AC), and its silver particles are reduced by L-ascorbic acid (L-AC). The surface of CeO ₂ -PEI is loaded with silver through a complexing reaction to produce a cerium oxide-based sunscreen that can resist blue light. Material (Ag NPs@CeO ₂ -PEI). At the same time, the spherical morphology obtained by SEM observation is conducive to light refraction and absorption, and a higher specific surface area is more conducive to resisting blue light and ultraviolet rays. The FTIR chart and XRD chart were used to prove that PEI was successfully compounded with cerium oxide CeO ₂ ; the EDS chart was used to confirm that CeO ₂ -PEI successfully loaded the silver element; the UV spectrum chart was used to measure that the blue light sunscreen material has high absorbance. It has the function of resisting blue light and resisting ultraviolet rays; using the anti-blue light test card recognized on the market to further confirm that the material has the ability to resist blue light; using antibacterial and sterilization experimental data to prove that the anti-blue light sunscreen material also has a certain antibacterial effect.

Based on the disclosure and teachings of the above description, those skilled in the art of the present invention can also make changes and modifications to the above embodiments, such as arbitrarily changing the composition of polyethylenimine (PEI), cerium nitrate hexahydrate (Ce(NO ₃ ) ₃ ·6H2O), silver nitrate (NS), triethylamine (TEA), etc., to form different samples. The embodiments of the present invention do not exhaust all the proportions, but any composition based on the experimental principles in the embodiments of the present invention Any modifications made based on the present invention are not limited to the specific embodiments disclosed and described above, and any above-mentioned modifications and changes to the invention should also fall within the protection scope of the claims of the present invention.

Claims (3)

1. A ceria-based sun protection material that is resistant to blue light, comprising: polyethyleneimine, triethylamine, cerium nitrate hexahydrate, L-ascorbic acid, silver nitrate; the molar ratio of the polyethyleneimine to the cerium nitrate hexahydrate is 2-4:1-10; the molar ratio of the triethylamine to the cerium nitrate hexahydrate is 5-20:1-200; the molar ratio of the L-ascorbic acid to the cerium nitrate hexahydrate is 1-2:120-600; the molar ratio of the silver nitrate to the cerium nitrate hexahydrate is 1-2:100-250;

the preparation method of the cerium oxide-based sun-screening material capable of resisting blue light comprises the following steps:

s1, dissolving cerium nitrate hexahydrate in absolute ethyl alcohol, and stirring to fully dissolve to obtain a solution A;

s2, dissolving polyethyleneimine in absolute ethyl alcohol, and stirring to fully dissolve to obtain a solution B;

s3, slowly adding the solution B into the solution A until a large amount of white floccules appear, adding triethylamine, and reacting for a certain time t ₁ Water cooling, adding pure water for hydrolysis reaction, and continuously coolingTime t ₂ After which the reaction is carried out at room temperature for a certain time t ₃ Obtaining a suspension C;

s4, washing the suspension C to be neutral by pure water, further centrifugally washing by absolute ethyl alcohol and pure water, drying and grinding to obtain solid powder E;

s5, dispersing the solid powder E in pure water by ultrasonic, and dripping 2V/V% ammonia water to obtain turbid liquid F;

s6, adding the silver ammonia solution H into the turbid liquid F, performing light-shielding treatment, and reacting for a certain time t ₄ Then adding L-ascorbic acid aqueous solution G under high-speed stirring, changing the rotating speed, and reacting for a certain time t at room temperature ₅ Obtaining turbid liquid I;

s7, carrying out suction filtration on the turbid liquid I to obtain a gray brown precipitate, respectively washing with absolute ethyl alcohol and pure water, and drying to obtain gray brown powder, thus obtaining the cerium oxide-based sun-screening material capable of resisting blue light;

the concentration of the solution A is 30W/V-50W/V;

the concentration of the solution B is 2.5W/V-10W/V;

reaction time t in step S3 ₁ For 20-60 min, cooling time t ₂ 1-15 min, reaction time t at room temperature ₃ 1-4 h;

the concentration of the solid powder E in the step S5 is 1-10W/V%;

the step S6 further includes:

dissolving L-ascorbic acid in pure water, and stirring thoroughly to obtain L-ascorbic acid aqueous solution G, wherein the concentration of the L-ascorbic acid aqueous solution is 2-5W/V%;

reaction time t in step S6 ₄ The high-speed stirring is carried out for 10-30 min at a rotating speed of 1000-2000 rad/min for 1-5 min, and the room temperature reaction time t is changed at a rotating speed of 400-600 rad/min ₅ 2-10 h.

2. The ceria-based blue light resistant sunscreen material of claim 1, further comprising in step S6:

dissolving silver nitrate in pure water, stirring thoroughly, and dripping 2V/V% ammonia water to obtain silver ammonia solution H with concentration of 0.1-0.5W/V%.

3. The blue light resistant ceria-based sunscreen material of claim 1 wherein said step S4 and step S7 are both drying conditions of 1-3h at 95-115 ℃.