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CN116712029A - An eye refractive error detection device and method - Google Patents

An eye refractive error detection device and method Download PDF

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CN116712029A
CN116712029A CN202310872709.XA CN202310872709A CN116712029A CN 116712029 A CN116712029 A CN 116712029A CN 202310872709 A CN202310872709 A CN 202310872709A CN 116712029 A CN116712029 A CN 116712029A
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eye
lens
human eye
refractive error
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李抄
刘义兵
孙昭
刘力威
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Ningbo Flo Optical Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/103Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0008Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0016Operational features thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/0091Fixation targets for viewing direction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/1005Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring distances inside the eye, e.g. thickness of the cornea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/102Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]

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Abstract

本发明涉及一种眼屈光不正检测装置和方法,装置包括接目透镜和第一分光镜,此外还包括以接目透镜和第一分光镜为公共元件且并列设置的:用于获取被测人眼屈光不正信息的屈光度检测光路;用于为被测人眼提供固视图像,使被测人眼稳定注视的视标光路;用于对被测人眼进行三维定位,以及获取被测人眼眼角膜成像信息的眼位置监测光路;用于采集被测人眼眼后节区图像信息的眼后节OCT测量光路:通过本发明可以在获取眼睛屈光不正信息,还能同时测量出眼前节和眼后节区域,并得出眼轴长度等眼参数,对青少年近视分析具有准确性提高的创造性意义。

The invention relates to an eye refractive error detection device and method. The device includes an eye lens and a first beam splitter. In addition, it also includes an eye lens and a first beam splitter as common components and arranged side by side: used to obtain the measured The optical path for diopter detection of refractive error information of the human eye; used to provide a fixation image for the human eye to be tested and the visual mark optical path to stabilize the gaze of the human eye under test; used for three-dimensional positioning of the human eye under test and to obtain the measured human eye Eye position monitoring optical path for human eye corneal imaging information; posterior segment OCT measurement optical path for collecting posterior segment image information of the human eye under test: Through the present invention, the refractive error information of the eye can be obtained, and the refractive error information can also be measured at the same time. Anterior segment and posterior segment area, and ocular parameters such as axial length are obtained, which has creative significance in improving the accuracy of myopia analysis in adolescents.

Description

一种眼屈光不正检测装置和方法Eye refractive error detection device and method

技术领域Technical field

本发明涉及眼科学与技术领域,具体而言,涉及一种眼屈光不正检测装置和方法。The present invention relates to the field of ophthalmology and technology, and specifically to an eye refractive error detection device and method.

背景技术Background technique

人眼近视主要分为屈光性近视和轴性近视两类,屈光性近视主要由于角膜或晶状体曲率过大或各屈光成分之间组合异常导致,轴性近视是由于眼轴延长,眼轴长度超出正常范围,一般眼轴加长1mm,近视度数增加200-300度。不同原因的近视应采取不同防控措施,因此眼轴长测量对于近视防控具有重要作用。Human myopia is mainly divided into two categories: refractive myopia and axial myopia. Refractive myopia is mainly caused by excessive curvature of the cornea or lens or abnormal combination of refractive components. Axial myopia is caused by the elongation of the axial length of the eye. The axial length exceeds the normal range. Generally, the axial length of the eye is lengthened by 1 mm, and the degree of myopia increases by 200-300 degrees. Different prevention and control measures should be taken for different causes of myopia, so the measurement of axial length of the eye plays an important role in the prevention and control of myopia.

眼轴长是人眼结构的重要参数,在人眼中,角膜正中到视神经与视网膜黄斑中心窝之间的一条假设线,称为眼轴,其长度一般在22~27毫米范围内,平均为24毫米。由上可知,眼轴长是判断人眼屈光不正的重要指标,能区别出真性近视与假性近视,也是测算白内障手术后人工晶体参数的重要指标。The axial length of the eye is an important parameter of the structure of the human eye. In the human eye, a hypothetical line from the center of the cornea to the optic nerve and the fovea of the retinal macula is called the axial length. Its length is generally in the range of 22 to 27 mm, with an average of 24 mm. It can be seen from the above that the axial length of the eye is an important indicator for judging the refractive error of the human eye. It can distinguish true myopia from pseudomyopia. It is also an important indicator for measuring intraocular lens parameters after cataract surgery.

现有技术中提供的一种屈光不正和眼轴长同步测量的方法和装置,该技术方案将时域光学干涉技术与哈特曼波前探测技术相结合,实现了眼周长度和屈光不正的共同检测,为筛查近视情况提供了技术支撑。但该技术方案对于固视能力较弱的少年儿童则不能有效、准确的判断屈光度和测量眼轴长度,进而弱化了其在青少年中近视检测的实用价值。A method and device for synchronous measurement of refractive error and axial length of the eye are provided in the prior art. This technical solution combines time-domain optical interference technology with Hartmann wavefront detection technology to achieve ocular circumferential length and refraction. The common detection of irregularities provides technical support for screening myopia. However, this technical solution cannot effectively and accurately judge the diopter and measure the axial length of children with weak visual fixation ability, thus weakening its practical value in myopia detection among teenagers.

发明内容Contents of the invention

本发明的目的在于克服现有技术缺陷,且提供了一种结合了四个光路且低成本的屈光不正检测装置和方法。The purpose of the present invention is to overcome the shortcomings of the prior art and provide a low-cost refractive error detection device and method that combines four optical paths.

本发明提供的屈光不正检测装置,其技术方案如下:The technical solution of the refractive error detection device provided by the present invention is as follows:

一种眼屈光不正检测装置,包括接目透镜和第一分光镜,同时还包括以所述接目透镜和所述第一分光镜为公共元件且并列设置的:An eye refractive error detection device includes an eye lens and a first beam splitter, and also includes the eye lens and the first beam splitter as common components and arranged side by side:

基于圆环共焦方式,用于获取被测人眼屈光不正信息的屈光度检测光路;Based on the ring confocal method, the diopter detection optical path is used to obtain the refractive error information of the human eye under test;

用于为所述被测人眼提供固视图像,使所述被测人眼稳定注视的视标光路;An optotype light path used to provide a fixation image for the human eye to be tested and to stabilize the gaze of the human eye to be tested;

用于对所述被测人眼进行三维定位,以及获取所述被测人眼眼角膜成像信息的眼位置监测光路;An eye position monitoring optical path for three-dimensional positioning of the human eye under test and obtaining corneal imaging information of the human eye under test;

用于采集所述被测人眼眼后节区图像信息的眼后节OCT测量光路。The posterior segment OCT measurement light path is used to collect the image information of the posterior segment area of the human eye under test.

采用上述技术方案,与现有技术相比,本发明申请所提供的技术方案至少可以带来的有益效果有:通过并列设置屈光度检测光路、视标光路、眼位置成像光路和眼后节OCT测量光路,在测人眼时,能根据具体需要利用眼位置成像光路确定被测人眼位置和眼角膜信息、利用视标光路使被测人眼稳定注视、利用屈光度检测光路获取被测人眼屈光不正信息和利用眼后节OCT测量光路采集眼后节图像信息,在测试屈光不正信息的过程中,能够实时提供固视图像,使被测人眼稳定注视,再加上屈光不正检测采用圆环共焦方式,从而更加适合青少年以及儿童视力检测。与此同时,在测量眼轴时无需要快速切换光路,更无须采用振镜来进行眼前节和眼后节的光路切换,从而减小了光路一致性调整难度,稳定性提升,成本也大幅度下降,有利于该技术产品的推广应用。据此,本技术方案能准确的判断屈光度和测量眼轴长度,在青少年中近视检测方面具有较高实用价值。Using the above technical solution, compared with the existing technology, the technical solution provided by the present invention can at least bring about the following beneficial effects: by setting the diopter detection light path, the visual mark light path, the eye position imaging light path and the posterior segment OCT measurement in parallel Optical path, when measuring the human eye, the eye position imaging optical path can be used to determine the position of the human eye and cornea information according to specific needs, the optotype optical path can be used to stabilize the gaze of the human eye under test, and the diopter detection optical path can be used to obtain the diopter of the human eye under test. Optical error information and posterior segment image information are collected using the posterior segment OCT measurement light path. During the process of testing refractive error information, a fixation image can be provided in real time to stabilize the gaze of the tested human eye, coupled with refractive error detection The ring confocal method is adopted, making it more suitable for vision testing of teenagers and children. At the same time, there is no need to quickly switch the optical path when measuring the eye axis, and there is no need to use a galvanometer to switch the optical path between the anterior segment and the posterior segment, thereby reducing the difficulty of adjusting the consistency of the optical path, improving stability, and significantly increasing the cost. decline, which is conducive to the promotion and application of this technology product. Accordingly, this technical solution can accurately determine the diopter and measure the axial length of the eye, and has high practical value in detecting myopia in adolescents.

作为优选,所述屈光度检测光路包括用于产生检测光信号的光源组件,以及沿所述检测光信号传播方向设置的中孔反射镜和用于引导所述检测光信号进入所述被测人眼并形成反射光信号原路返回入所述中孔反射镜的屈光路径定义模块,同时还包括屈光不正信号采集模块,所述屈光不正信号采集模块用于接收所述反射光信号进入所述中孔反射镜后射出的部分信号光;这样便能够顺利的获取被测人眼屈光不正信息。Preferably, the diopter detection light path includes a light source component for generating a detection light signal, and a mesoporous reflector arranged along the propagation direction of the detection light signal and for guiding the detection light signal into the human eye under test. And form a refractive path definition module for the reflected light signal to return to the original path of the mesopore reflector, and also include a refractive error signal acquisition module, the refractive error signal acquisition module is used to receive the reflected light signal entering the Part of the signal light emitted from the middle hole reflector is used to obtain the refractive error information of the human eye under test smoothly.

作为优选,所述光源组件包括沿所述检测光信号传播方向设置的可移动屈光检测光源、可移动聚焦透镜、可移动环形光阑和第一透镜;采用可移动环形光阑作为光路成像器件,可以降低造价成本,再结合可移动屈光检测光源和可移动聚焦透镜,大大方便了对被测人眼屈光不正的准确检测。Preferably, the light source assembly includes a movable refractive detection light source, a movable focusing lens, a movable annular diaphragm and a first lens arranged along the propagation direction of the detection light signal; the movable annular diaphragm is used as the optical path imaging device , can reduce the cost, and combined with the movable refractive detection light source and the movable focusing lens, greatly facilitates the accurate detection of the refractive error of the human eye under test.

作为优选,所述屈光路径定义模块包括沿所述检测光信号传播方向设置的第三分光镜、第二分光镜、所述第一分光镜和所述接目透镜;这样设置之后,经过第一透镜出射的检测光信号,经中孔反射镜反射后可以进入第三分光镜,第三分光镜再次反射,进过第二分光镜透射、第一分光镜透射后,通过接目透镜投射到人眼中;随后可移动环形光阑便能在眼底聚焦成像,形成眼底反射光原路返回,再经过中孔反射镜时,部分眼底反射光能够经由中孔反射镜中间孔透射,进入屈光不正信号采集模块且被接收。Preferably, the refractive path definition module includes a third beam splitter, a second beam splitter, the first beam splitter and the eye lens arranged along the propagation direction of the detection light signal; after such arrangement, after passing through the third beam splitter, The detection light signal emitted from a lens can enter the third beam splitter after being reflected by the middle hole mirror. The third beam splitter reflects again, passes through the second beam splitter and the first beam splitter, and is projected to the eye lens through the eye lens. In the human eye; the movable annular diaphragm can then focus the image on the fundus, causing the fundus reflected light to return along its original path. When passing through the mesopore reflector, part of the fundus reflected light can be transmitted through the middle hole of the mesopore reflector and enter the refractive error. The signal acquisition module is received.

作为优选,所述屈光不正信号采集模块包括沿光传播方向设置的反射镜、第二透镜、第一可移动透镜、第三透镜和第一图像传感器;经过这样设置后,部分眼底反射光能够经由中孔反射镜中间孔透射,进入反射镜反射后,逐一经过第二透镜、第一可移动透镜、第三透镜,最后被第一图像传感器接收,至此便顺理成章的获取被测人眼屈光不正信息。Preferably, the refractive error signal collection module includes a reflector arranged along the light propagation direction, a second lens, a first movable lens, a third lens and a first image sensor; after such arrangement, part of the fundus reflected light can It is transmitted through the middle hole of the middle hole mirror, and after reflection by the mirror, it passes through the second lens, the first movable lens, and the third lens one by one, and is finally received by the first image sensor. At this point, the refraction of the human eye under test can be obtained logically. Incorrect information.

作为优选,所述视标光路包括沿光传播方向设置的可移动视标、第四透镜、所述第三分光镜、所述第二分光镜、所述第一分光镜和所述接目透镜;设置可移动视标能够根据不同视力特征的人群提供相应的固视图像,达到稳定注视的效果,为屈光不正信息的获取提供了技术支持。Preferably, the sight mark optical path includes a movable sight mark arranged along the light propagation direction, a fourth lens, the third beam splitter, the second beam splitter, the first beam splitter and the eye lens. ; Setting up movable visual targets can provide corresponding fixation images according to people with different vision characteristics, achieve a stable gaze effect, and provide technical support for the acquisition of refractive error information.

作为优选,所述可移动视标、所述可移动屈光检测光源、所述可移动聚焦透镜、所述可移动环形光阑和所述第一可移动透镜被设置为同步移动;这样为检测屈光不正提供了一个灵活的物像共轭场景,能有效的根据被测者眼睛特征获取屈光不正信息。Preferably, the movable sight mark, the movable refractive detection light source, the movable focusing lens, the movable annular diaphragm and the first movable lens are set to move synchronously; in this way, detection Refractive error provides a flexible object-image conjugate scene, which can effectively obtain refractive error information based on the characteristics of the subject's eyes.

作为优选,所述眼位置成像光路包括第一眼周照明光源和第二眼周照明光源,所述第一眼周照明光源、所述第二眼周照明光源辐照所述被测人眼,形成反射辐照光信号,所述眼位置成像光路还包括沿所述反射辐照光信号传播方向设置的所述接目透镜、所述第一分光镜、第五透镜和第二图像传感器,以及相对所述被测人眼中轴线对称倾斜设置的照明光源和第一探测器;所述第二图像传感器用于监测所述被测人眼位置,并指导操作者和被测者将所述被测人眼与所述接目透镜中轴对齐,所述第一探测器用于接收所述照明光源引起的所述被测人眼反射信号图像;这样不经实现了被测人眼的三维定位,而且,照明光源的光被眼睛角膜反射后进入位置探测器,由于眼睛前后位置的改变将引起探测器中信号分布的变化,因此通过探测器可以准确监测眼睛相对于接目透镜的前后位置,即角膜到接目透镜的距离。Preferably, the eye position imaging light path includes a first periorbital illumination light source and a second periorbital illumination light source, and the first periorbital illumination light source and the second periorbital illumination light source irradiate the human eye under test, To form a reflected irradiation light signal, the eye position imaging optical path further includes the eye lens, the first beam splitter, the fifth lens and a second image sensor arranged along the propagation direction of the reflected irradiation light signal, and An illumination light source and a first detector arranged symmetrically and tilted relative to the axis of the human eye under test; the second image sensor is used to monitor the position of the human eye under test and guide the operator and the person being tested to move the human eye under test The human eye is aligned with the central axis of the eye lens, and the first detector is used to receive the reflected signal image of the human eye under test caused by the illumination light source; in this way, the three-dimensional positioning of the human eye under test is achieved, and , the light from the illumination source is reflected by the cornea of the eye and then enters the position detector. Since changes in the front and back position of the eye will cause changes in signal distribution in the detector, the detector can accurately monitor the front and back position of the eye relative to the eye lens, that is, the cornea. The distance to the eye lens.

作为优选,所述眼后节OCT测量光路包括沿光传播方向设置的OCT光路光源和用于将所述OCT光路光源发出的光信号分成样品光信号和参考光信号并输出的光纤耦合器,同时还包括沿所述样品光信号传播方向设置的第六透镜、振镜、第二可移动透镜、所述第二分光镜、所述第一分光镜和所述接目透镜,以及沿所述参考光信号传播方向设置的第七透镜、可移动参考镜和与所述光纤耦合器光信号导通的第二探测器;所述样品光信号进入所述被测人眼眼后节区,经反射形成样品反射光信号后原路返回入所述光纤耦合器,所述参考光信号经所述可移动参考镜反射,形成参考反射光信号后原路返回入所述光纤耦合器,所述样品反射光信号与所述参考反射光信号于所述光纤耦合器干涉形成相干光信号,所述第二探测器用于获取所述相干光信号;这样设置后,能有效的采集被测人眼视网膜OCT图像,再结合眼位置成像光路采集的眼角膜,便可以计算出眼轴长,至此实现了眼前节信号和眼后节信号的同步采集。Preferably, the posterior segment OCT measurement optical path includes an OCT optical path light source arranged along the light propagation direction and an optical fiber coupler for dividing the optical signal emitted by the OCT optical path light source into a sample optical signal and a reference optical signal and outputting them, while It also includes a sixth lens, a galvanometer, a second movable lens, the second beam splitter, the first beam splitter and the eyepiece lens arranged along the propagation direction of the sample optical signal, and along the reference The seventh lens, the movable reference mirror, and the second detector connected to the optical signal of the optical fiber coupler are arranged in the propagation direction of the optical signal; the sample optical signal enters the posterior segment area of the human eye under test and is reflected The sample reflected optical signal is formed and then returned to the optical fiber coupler along the original path. The reference optical signal is reflected by the movable reference mirror. The reference reflected optical signal is formed and then returned to the optical fiber coupler along the original path. The sample is reflected The optical signal and the reference reflected optical signal interfere at the optical fiber coupler to form a coherent optical signal, and the second detector is used to acquire the coherent optical signal; after such an arrangement, the OCT image of the retina of the human eye under test can be effectively collected. , combined with the cornea collected by the eye position imaging optical path, the axial length of the eye can be calculated, thus achieving the simultaneous collection of anterior segment signals and posterior segment signals.

本发明提供的眼视力检测方法,其技术方案如下:The technical solution of the eye vision detection method provided by the present invention is as follows:

一种眼视力检测方法,基于本申请技术方案所述的屈光不正检测装置,包括如下步骤:An eye vision detection method, based on the refractive error detection device described in the technical solution of this application, includes the following steps:

步骤一、操作者通过所述眼位置成像光路判断所述被测人眼位置并指导完成所述被测人眼的位置对准;Step 1: The operator determines the position of the human eye under test through the eye position imaging light path and guides the completion of the position alignment of the human eye under test;

步骤二、通过所述视标光路使所述被测人眼稳定注视,并通过所述屈光度检测光路对所述被测人眼进行屈光不正信息检测,获取所述被测人眼对应的屈光不正信息检测结果;Step 2: Make the human eye under test stably gaze through the optotype light path, and detect the refractive error information of the human eye under test through the diopter detection light path, and obtain the refractive error corresponding to the human eye under test. Photo-incorrect information detection results;

步骤三、同步进行利用所述眼位置监测光路获取所述被测人眼眼角膜图像信息和利用所述眼后节OCT测量光路获取所述被测人眼视网膜OCT成像信息;Step 3: Synchronize the use of the eye position monitoring light path to obtain the cornea image information of the human eye under test and the posterior segment OCT measurement light path to obtain the retinal OCT imaging information of the human eye under test;

步骤四、根据所述眼角膜图像信息和所述视网膜OCT成像信息,结合所述眼后节OCT测量光路结构特性,计算出所述被测人眼眼轴长度;Step 4: Calculate the axial length of the human eye under test based on the corneal image information and the retinal OCT imaging information, combined with the posterior segment OCT measurement optical path structural characteristics;

步骤五、利用所述屈光不正信息检测结果和所述眼轴长度,对所述被测人眼视力状况做出结论。Step 5: Use the refractive error information detection result and the axial length of the eye to draw a conclusion about the visual acuity of the human eye under test.

采用上述技术方案,与现有技术相比,本发明申请所提供的技术方案至少可以带来的有益效果有:本方案基于本申请技术方案所述的屈光不正检测装置,通过先进行屈光度测量,再采集视网膜图像,最后得到眼轴长,在测量屈光度和眼周长时大大降低成本,对于青少年近视程度的评估具有较高准确性。Using the above technical solution, compared with the existing technology, the technical solution provided by the present application can at least bring about the following beneficial effects: This solution is based on the refractive error detection device described in the technical solution of the present application, by first measuring the diopter , then collect retinal images, and finally obtain the axial length of the eye, which greatly reduces the cost when measuring diopter and eye circumference, and has high accuracy in assessing the degree of myopia in teenagers.

附图说明Description of the drawings

图1为本发明的一种眼屈光不正检测装置光路结构示意图;Figure 1 is a schematic diagram of the optical path structure of an eye refractive error detection device according to the present invention;

图2为本发明的一种眼屈光不正检测装置中屈光度检测光路结构示意图;Figure 2 is a schematic structural diagram of the diopter detection optical path in an eye refractive error detection device of the present invention;

图3为本发明的一种眼屈光不正检测装置获取的眼周成像图;Figure 3 is a periocular imaging diagram obtained by an eye refractive error detection device of the present invention;

图4为通过本发明实施例的一种眼屈光不正检测装置获取的眼底反射的圆环图像;Figure 4 is a ring image of fundus reflection obtained by an eye refractive error detection device according to an embodiment of the present invention;

图5为通过本发明实施例的一种眼屈光不正检测装置获取的视网膜OCT图像。Figure 5 is a retinal OCT image obtained by an eye refractive error detection device according to an embodiment of the present invention.

其中,图中所标注的数字分别代表:1、被测人眼;4、接目透镜;5、第一分光镜;6、第五透镜;7、第二图像传感器;8、第二分光镜;9、第三分光镜;10、第四透镜;11、可移动视标;13、中孔反射镜;14、第一透镜;15、可移动环形光阑;16、可移动聚焦透镜;17、可移动屈光检测光源;18、反射镜;19、第二透镜;20、第一可移动透镜;21、第三透镜;22、第一图像传感器;23、第二可移动透镜;24、振镜;25、第六透镜;26、OCT光路光源;27、第二探测器;28、第七透镜;29、可移动参考镜;30、光纤耦合器;31、光源组件;32、屈光路径定义模块;33、屈光不正信号采集模块;201、照明光源;202、第一探测器;301、第一眼周照明光源;302、第二眼周照明光源;3012、样品臂端口;3013、光源臂端口;3014、参考臂端口;3015、检测臂端口。Among them, the numbers marked in the figure respectively represent: 1. Human eye under test; 4. Eye lens; 5. First beam splitter; 6. Fifth lens; 7. Second image sensor; 8. Second beam splitter ; 9. The third beam splitter; 10. The fourth lens; 11. Movable sight mark; 13. Middle hole reflector; 14. First lens; 15. Movable annular diaphragm; 16. Movable focusing lens; 17 , movable refractive detection light source; 18. Reflector; 19. Second lens; 20. First movable lens; 21. Third lens; 22. First image sensor; 23. Second movable lens; 24. Galvanometer; 25. Sixth lens; 26. OCT optical path light source; 27. Second detector; 28. Seventh lens; 29. Movable reference mirror; 30. Fiber optic coupler; 31. Light source assembly; 32. Diopter Path definition module; 33. Refractive error signal acquisition module; 201. Illumination source; 202. First detector; 301. First periorbital illumination source; 302. Second periorbital illumination source; 3012. Sample arm port; 3013 , light source arm port; 3014, reference arm port; 3015, detection arm port.

具体实施方式Detailed ways

下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述。The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.

本发明实施例提供的一种眼屈光不正检测装置,包括接目透镜4和第一分光镜5,此外还包括以接目透镜4和第一分光镜5为公共元件且并列设置的:An eye refractive error detection device provided by an embodiment of the present invention includes an eye lens 4 and a first beam splitter 5. In addition, the eye lens 4 and the first beam splitter 5 are common components and are arranged side by side:

用于获取被测人眼1屈光不正信息的屈光度检测光路;The diopter detection light path used to obtain the refractive error information of the human eye under test 1;

用于为被测人眼1提供固视图像,使被测人眼1稳定注视的视标光路;Optotype light path used to provide a fixation image for the human eye 1 to be tested and to stabilize the gaze of the human eye 1 under test;

用于对被测人眼1进行三维定位,以及获取被测人眼1眼角膜成像信息的眼位置监测光路;Eye position monitoring optical path used for three-dimensional positioning of the human eye 1 under test and obtaining corneal imaging information of the human eye 1 under test;

用于采集被测人眼1眼后节区图像信息的眼后节OCT测量光路。Posterior segment OCT measurement light path used to collect image information of the posterior segment area of 1 eye of the human eye under test.

本实施例中,屈光度检测光路包括沿光传播方向设置的用于产生检测光信号的光源组件31、中孔反射镜13和用于引导检测光信号进入被测人眼并形成反射光信号原路返回入中孔反射镜13的屈光路径定义模块32;同时还包括屈光不正信号采集模块33,屈光不正信号采集模块33用于接收反射光信号进入中孔反射镜13后射出的部分信号光。In this embodiment, the diopter detection optical path includes a light source component 31 arranged along the light propagation direction for generating a detection light signal, a middle hole reflector 13 and a medium hole reflector 13 for guiding the detection light signal into the human eye being measured and forming the original path of the reflected light signal. The refractive path definition module 32 returns to the mesobore reflector 13; it also includes a refractive error signal acquisition module 33. The refractive error signal collection module 33 is used to receive part of the signal emitted after the reflected light signal enters the mesobore reflector 13. Light.

本实施例中,光源组件31包括沿光传播方向设置的可移动屈光检测光源17、可移动聚焦透镜16、可移动环形光阑15和第一透镜14。其中可移动屈光检测光源17为可移动的近红外LED光源,波长810-870nm。可移动环形光阑15的透光区域为圆环,圆环内径2-3mm,圆环宽度0.3-0.4mm。In this embodiment, the light source assembly 31 includes a movable refraction detection light source 17 arranged along the light propagation direction, a movable focusing lens 16, a movable annular diaphragm 15 and a first lens 14. The movable refraction detection light source 17 is a movable near-infrared LED light source with a wavelength of 810-870nm. The light-transmitting area of the movable annular diaphragm 15 is a ring, the inner diameter of the ring is 2-3mm, and the width of the ring is 0.3-0.4mm.

本实施例中,屈光路径定义模块32包括沿检测光信号传播方向设置的第三分光镜9、第二分光镜8、第一分光镜5和接目透镜4。屈光不正信号采集模块33包括沿光传播方向设置的反射镜18、第二透镜19、第一可移动透镜20、第三透镜21和第一图像传感器22。检测光信号通过接目透镜4投射到人眼中,可移动环形光阑15在眼底聚焦成像,形成眼底反射光原路返回,经过中孔反射镜13时部分返回光经由中间孔透射,再经过反射镜18反射、第二透镜19聚焦,最后经由第一可移动透镜20和第三透镜21在第一图像传感器22中形成眼底反射的圆环像。In this embodiment, the refractive path definition module 32 includes a third beam splitter 9 , a second beam splitter 8 , a first beam splitter 5 and an eyepiece lens 4 arranged along the propagation direction of the detection light signal. The refractive error signal collection module 33 includes a reflector 18, a second lens 19, a first movable lens 20, a third lens 21 and a first image sensor 22 arranged along the light propagation direction. The detection light signal is projected into the human eye through the eye lens 4, and the movable annular diaphragm 15 focuses the image on the fundus, forming the fundus reflected light to return to the original path. When passing through the middle hole reflector 13, part of the returned light is transmitted through the middle hole, and then reflected The mirror 18 reflects and the second lens 19 focuses, and finally a ring image reflected by the fundus is formed in the first image sensor 22 via the first movable lens 20 and the third lens 21 .

本实施例中,视标光路包括沿光传播方向设置的可移动视标11、第四透镜10、第三分光镜9、第二分光镜8、第一分光镜5和接目透镜4。在本实施例中,可移动视标11、可移动屈光检测光源17、可移动聚焦透镜16、可移动环形光阑15和第一可移动透镜20被设置为同步移动。In this embodiment, the optical path of the visual target includes a movable visual target 11 arranged along the light propagation direction, a fourth lens 10 , a third beam splitter 9 , a second beam splitter 8 , a first beam splitter 5 and an eyepiece lens 4 . In this embodiment, the movable visual mark 11, the movable refraction detection light source 17, the movable focusing lens 16, the movable annular diaphragm 15 and the first movable lens 20 are set to move synchronously.

本实施例中,眼位置成像光路包括第一眼周照明光源301和第二眼周照明光源302,第一眼周照明光源301、第二眼周照明光源302辐照被测人眼,形成反射辐照光信号,眼位置成像光路还包括沿反射辐照光信号传播方向设置的接目透镜4、第一分光镜5、第五透镜6和第二图像传感器7,以及相对被测人眼中轴线对称倾斜设置的照明光源201和第一探测器202;第二图像传感器7用于监测被测人眼位置,并指导操作者和被测者将被测人眼与接目透镜4中轴对齐,第一探测器202用于接收照明光源201引起的被测人眼反射信号图像。In this embodiment, the eye position imaging light path includes a first periorbital illumination light source 301 and a second periorbital illumination light source 302. The first periorbital illumination light source 301 and the second periorbital illumination light source 302 irradiate the human eye under test to form a reflection. The irradiation light signal and eye position imaging optical path also include an eye lens 4, a first beam splitter 5, a fifth lens 6 and a second image sensor 7 arranged along the propagation direction of the reflected irradiation light signal, and relative to the eye axis of the person being measured The illumination light source 201 and the first detector 202 are symmetrically tilted; the second image sensor 7 is used to monitor the position of the human eye under test, and guide the operator and the person being tested to align the human eye under test with the central axis of the eye lens 4, The first detector 202 is used to receive the reflected signal image of the human eye under test caused by the illumination light source 201.

本实施例中,眼后节OCT测量光路包括沿光传播方向设置的OCT光路光源26和用于将OCT光路光源26发出的光信号分成样品光信号和参考光信号并输出的光纤耦合器30,同时还包括沿样品光信号传播方向设置的第六透镜25、振镜24、第二可移动透镜23、第二分光镜8、第一分光镜5和接目透镜4,以及沿参考光信号传播方向设置的第七透镜28、可移动参考镜29和与光纤耦合器30光信号导通的第二探测器27;样品光信号进入被测人眼眼后节区,经反射形成样品反射光信号后原路返回入光纤耦合器30,参考光信号经可移动参考镜29反射,形成参考反射光信号后原路返回入光纤耦合器30,样品反射光信号与参考反射光信号于光纤耦合器30干涉形成相干光信号,第二探测器27用于获取相干光信号。In this embodiment, the posterior segment OCT measurement optical path includes an OCT optical path light source 26 arranged along the light propagation direction and an optical fiber coupler 30 for dividing the optical signal emitted by the OCT optical path light source 26 into a sample optical signal and a reference optical signal and outputting them. At the same time, it also includes a sixth lens 25, a galvanometer 24, a second movable lens 23, a second beam splitter 8, a first beam splitter 5 and an eyepiece lens 4 arranged along the propagation direction of the sample optical signal, as well as along the propagation direction of the reference optical signal. The seventh lens 28 set in the direction, the movable reference mirror 29 and the second detector 27 connected with the optical signal of the optical fiber coupler 30; the sample optical signal enters the posterior segment area of the human eye under test and is reflected to form a sample reflected optical signal. Then the original path returns to the fiber coupler 30. The reference light signal is reflected by the movable reference mirror 29 to form a reference reflected light signal and then returns to the fiber coupler 30. The sample reflected light signal and the reference reflected light signal are in the fiber coupler 30. The interference forms a coherent light signal, and the second detector 27 is used to acquire the coherent light signal.

本实施例中,光纤耦合器30上设置有样品臂端口3012、光源臂端口3013、参考臂端口3014和检测臂端口3015,OCT光路光源26发出的光信号经光源臂端口3013进入光纤耦合器30处理后,一部分经由样品臂端口3012出射,进入第六透镜25;另一部分经由参考臂端口3014出射,进入第七透镜28;相干光信号则通过检测臂端口3015传入第二探测器27。In this embodiment, the fiber coupler 30 is provided with a sample arm port 3012, a light source arm port 3013, a reference arm port 3014 and a detection arm port 3015. The optical signal emitted by the OCT optical path light source 26 enters the fiber coupler 30 through the light source arm port 3013. After processing, a part is emitted through the sample arm port 3012 and enters the sixth lens 25; the other part is emitted through the reference arm port 3014 and enters the seventh lens 28; the coherent optical signal is transmitted to the second detector 27 through the detection arm port 3015.

本实施例提供的一种眼视力检测方法,基于本实施例提供的的屈光不正检测装置,包括如下步骤:This embodiment provides a method for detecting eye vision, based on the refractive error detection device provided by this embodiment, including the following steps:

步骤一、操作者通过眼位置成像光路判断被测人眼1位置并指导完成被测人眼1的位置对准;Step 1: The operator determines the position of the human eye 1 under test through the eye position imaging light path and guides the completion of the position alignment of the human eye 1 under test;

步骤二、通过视标光路使被测人眼1稳定注视,并通过屈光度检测光路对被测人眼进行屈光不正信息检测,获取被测人眼1对应的屈光不正信息检测结果;Step 2: Make the tested human eye 1 gaze stably through the optotype optical path, and detect the refractive error information of the tested human eye through the diopter detection optical path to obtain the refractive error information detection result corresponding to the tested human eye 1;

步骤三、同步进行利用眼位置监测光路获取被测人眼1眼角膜图像信息和利用眼后节OCT测量光路获取被测人眼1视网膜OCT成像信息;Step 3: Synchronously use the eye position monitoring light path to obtain the cornea image information of the human eye 1 under test and use the posterior segment OCT measurement light path to obtain the retinal OCT imaging information of the human eye 1 under test;

步骤四、根据眼角膜图像信息和视网膜OCT成像信息,结合眼后节OCT测量光路结构特性,计算出被测人眼眼轴长度;Step 4: Calculate the axial length of the measured human eye based on the corneal image information and retinal OCT imaging information, combined with the optical path structural characteristics measured by posterior segment OCT;

步骤五、利用屈光不正信息检测结果和眼轴长度,对被测人眼视力状况做出结论。Step 5: Use the refractive error information detection results and axial length of the eye to draw conclusions about the visual acuity of the person being tested.

具体来说,操作者首先通过眼睛位置成像光路判断眼睛位置并指导被测试者完成眼睛的位置对准,眼睛对准后启动测量过程;首先进行屈光度测量,根据第一图像传感器22中圆环图像初步计算屈光度,并根据初步计算的屈光度前后移动可移动视标11、可移动屈光检测光源17、可移动聚焦透镜16、可移动环形光阑15和第一可移动透镜20,也就是图1中虚线框中的元件,进而精确测量眼睛屈光度;完成屈光度测量后,根据眼睛屈光度移动第二可移动透镜23,使OCT测量光在视网膜聚焦,随后调整可移动参考镜29位置,在第二探测器27中获得干涉信号;随后进行视网膜OCT图像采集,并同步采集探测器202中信号,准确计算角膜距离。根据视网膜图像、参考镜位置和角膜距离准确计算眼轴长。Specifically, the operator first determines the eye position through the eye position imaging light path and guides the subject to complete the eye position alignment. After the eye alignment, the measurement process is started; first, the diopter measurement is performed, and according to the ring image in the first image sensor 22 Preliminarily calculate the diopter, and move the movable sight mark 11, the movable refraction detection light source 17, the movable focusing lens 16, the movable annular diaphragm 15 and the first movable lens 20 back and forth according to the preliminary calculated diopter, that is, Figure 1 Components in the dotted box, and then accurately measure the eye diopter; after completing the diopter measurement, move the second movable lens 23 according to the eye diopter to focus the OCT measurement light on the retina, and then adjust the position of the movable reference mirror 29, and in the second detection The interference signal is obtained from the detector 27; then the retinal OCT image is collected, and the signal from the detector 202 is simultaneously collected to accurately calculate the corneal distance. Accurately calculate the axial length of the eye based on the retinal image, reference mirror position and corneal distance.

在计算眼轴长度时,因形成眼底干涉图像的前提是样品臂和参考臂的光程近似相等,即光程差小于光源相干长度。参考臂的光程由参考镜的位置Zref决定,样品臂的光程为角膜前表面到设备距离Zc(相对零点)、眼轴长L的和,因此当形成OCT干涉图像时,有;When calculating the axial length of the eye, the prerequisite for forming a fundus interference image is that the optical path lengths of the sample arm and the reference arm are approximately equal, that is, the optical path difference is less than the coherence length of the light source. The optical path of the reference arm is determined by the position of the reference mirror Zref. The optical path of the sample arm is the sum of the distance Zc from the front surface of the cornea to the device (relative zero point) and the axial length L. Therefore, when forming an OCT interference image, there is;

Zref+Δ=Zc+LZref+Δ=Zc+L

,其中Δ为根据视网膜前表面在OCT图像中的位置,因此眼轴长为;, where Δ is the position of the front retinal surface in the OCT image, so the axial length of the eye is;

L=Zref+Δ-ZcL=Zref+Δ-Zc

,在本方案中,Zc可由眼前节图像精确计算。, in this scheme, Zc can be accurately calculated from the anterior segment image.

在本实施例中,第二探测器27为光谱探测器,,探测光谱波长范围800-880nm。第二图像传感器7为面阵图像传感器,根据该图像可以准确监测眼睛位置,指导操作者将被测者眼睛与设备的光路中轴对齐。In this embodiment, the second detector 27 is a spectrum detector, detecting a spectrum wavelength range of 800-880 nm. The second image sensor 7 is an area array image sensor. According to the image, the eye position can be accurately monitored and the operator can be guided to align the subject's eyes with the central axis of the optical path of the device.

总之,尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对本实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。In summary, although the embodiments of the present invention have been shown and described, those of ordinary skill in the art will understand that various changes, modifications, and changes can be made to the embodiments without departing from the principles and spirit of the invention. Alterations and modifications, the scope of the invention is defined by the appended claims and their equivalents.

Claims (10)

1. An eye refractive error detection device comprises an eye lens (4) and a first spectroscope (5), and is characterized in that: the lens is characterized by also comprising a common element of the eye lens (4) and the first spectroscope (5) which are arranged in parallel:
based on a circular confocal mode, a diopter detection light path for acquiring the diopter error information of the detected human eye;
the optotype light path is used for providing a fixation image for the detected human eye and enabling the detected human eye to stably watch;
the eye position monitoring light path is used for carrying out three-dimensional positioning on the detected human eye and acquiring cornea imaging information of the detected human eye;
and the optical path for measuring the OCT of the posterior segment of the eye to be measured is used for collecting the image information of the posterior segment of the eye to be measured.
2. The refractive error detection apparatus according to claim 1, wherein: the diopter detection light path comprises a light source assembly (31) for generating detection light signals, a mesoporous reflector (13) arranged along the propagation direction of the detection light signals, and a Qu Guanglu path definition module (32) for guiding the detection light signals to enter the detected human eyes and forming reflected light signal paths to return into the mesoporous reflector (13), and also comprises a ametropia signal acquisition module (33), wherein the ametropia signal acquisition module (33) is used for receiving part of signal light emitted after the reflected light signals enter the mesoporous reflector (13).
3. The refractive error detection apparatus according to claim 2, wherein: the light source assembly (31) includes a movable refraction detection light source (17), a movable focusing lens (16), a movable annular diaphragm (15), and a first lens (14) disposed along a direction in which the detection light signal propagates.
4. A refractive error detection apparatus according to claim 3, characterized in that: the Qu Guanglu path definition module (32) comprises a third spectroscope (9), a second spectroscope (8), the first spectroscope (5) and the eye lens (4) which are arranged along the propagation direction of the detection light signals.
5. The refractive error detection apparatus according to claim 4, wherein: the refractive error signal acquisition module (33) comprises a reflecting mirror (18), a second lens (19), a first movable lens (20), a third lens (21) and a first image sensor (22), wherein the reflecting mirror (18), the second lens (19), the first movable lens (20), the third lens (21) and the first image sensor are arranged along the transmission direction of the reflected light signal emitted after entering the mesoporous reflecting mirror (13).
6. The refractive error detection apparatus according to claim 5, wherein: the optotype light path comprises a movable optotype (11), a fourth lens (10), a third spectroscope (9), a second spectroscope (8), a first spectroscope (5) and an eye lens (4) which are arranged along the propagation direction of an optotype signal.
7. The refractive error detection apparatus according to claim 6, wherein: the movable optotype (11), the movable refraction detection light source (17), the movable focusing lens (16), the movable annular diaphragm (15) and the first movable lens (20) are set to move in synchronization.
8. The refractive error detection apparatus according to claim 7, wherein: the eye position imaging optical path comprises a first eye circumference illumination light source (301) and a second eye circumference illumination light source (302), the first eye circumference illumination light source (301) and the second eye circumference illumination light source (302) irradiate the tested human eye to form a reflected irradiation light signal, the eye position imaging optical path further comprises the eye receiving lens (4), the first spectroscope (5), the fifth lens (6) and the second image sensor (7) which are arranged along the propagation direction of the reflected irradiation light signal, and an illumination light source (201) and a first detector (202) which are symmetrically arranged relative to the central axis of the tested human eye; the second image sensor (7) is used for monitoring the position of the detected human eye and guiding an operator and a detected person to align the detected human eye with the central axis of the eye lens (4), and the first detector (202) is used for receiving the reflected signal image of the detected human eye caused by the illumination light source (201).
9. The refractive error detection apparatus according to claim 8, wherein: the optical path for measuring the OCT of the posterior segment of the eye comprises an OCT optical path light source (26) arranged along the light propagation direction, an optical fiber coupler (30) for dividing an optical signal emitted by the OCT optical path light source (26) into a sample optical signal and a reference optical signal and outputting the sample optical signal, a sixth lens (25), a galvanometer (24), a second movable lens (23), the second spectroscope (8), the first spectroscope (5) and the eye lens (4) arranged along the light propagation direction, a seventh lens (28), a movable reference mirror (29) and a second detector (27) which are in optical signal conduction with the optical fiber coupler (30) arranged along the light propagation direction; the sample optical signal enters the rear section area of the eye of the tested person, the sample reflected optical signal is formed by reflection and then returned to the optical fiber coupler (30), the reference optical signal is reflected by the movable reference mirror (29), the reference reflected optical signal is formed and then returned to the optical fiber coupler (30), the sample reflected optical signal and the reference reflected optical signal interfere with each other in the optical fiber coupler (30) to form a coherent optical signal, and the second detector (27) is used for acquiring the coherent optical signal.
10. A visual acuity testing method is characterized in that: a refractive error detection device based on any one of claims 1-9, comprising the steps of:
step one, an operator judges the position of the detected human eye through the eye position imaging light path and guides the completion of the position alignment of the detected human eye;
step two, stably gazing the tested human eye through the optotype light path, and detecting the refractive error information of the tested human eye through the diopter detection light path to obtain a refractive error information detection result corresponding to the tested human eye;
step three, synchronously acquiring cornea image information of the eye of the tested person by using the eye position monitoring light path and OCT imaging information of the retina of the eye of the tested person by using the eye posterior segment OCT measuring light path;
step four, calculating the length of the eye axis of the detected human eye according to the cornea image information and the retina OCT imaging information and combining the optical path structural characteristics of the OCT measurement of the posterior segment of the eye;
and fifthly, judging the vision of the tested human eye by utilizing the refractive error information detection result and the eye axis length.
CN202310872709.XA 2023-07-17 2023-07-17 An eye refractive error detection device and method Pending CN116712029A (en)

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