CN110123262B - Ophthalmic measurement system and method - Google Patents
Ophthalmic measurement system and method Download PDFInfo
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- 238000000034 method Methods 0.000 title claims abstract description 28
- 238000005259 measurement Methods 0.000 title claims description 22
- 230000003287 optical effect Effects 0.000 claims abstract description 136
- 210000004087 cornea Anatomy 0.000 claims description 53
- 238000003384 imaging method Methods 0.000 claims description 50
- 238000005286 illumination Methods 0.000 claims description 34
- 210000001110 axial length eye Anatomy 0.000 claims description 12
- 238000000691 measurement method Methods 0.000 claims description 5
- 230000002452 interceptive effect Effects 0.000 claims description 3
- 238000012634 optical imaging Methods 0.000 claims description 3
- 230000004323 axial length Effects 0.000 abstract description 12
- 230000007547 defect Effects 0.000 abstract description 7
- 210000001508 eye Anatomy 0.000 description 169
- 210000000695 crystalline len Anatomy 0.000 description 58
- 238000012014 optical coherence tomography Methods 0.000 description 54
- 238000005516 engineering process Methods 0.000 description 15
- 210000001525 retina Anatomy 0.000 description 10
- 230000003595 spectral effect Effects 0.000 description 9
- 238000006073 displacement reaction Methods 0.000 description 8
- 230000010287 polarization Effects 0.000 description 7
- 238000012937 correction Methods 0.000 description 6
- 210000002159 anterior chamber Anatomy 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 206010025421 Macule Diseases 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 210000001747 pupil Anatomy 0.000 description 3
- 230000001427 coherent effect Effects 0.000 description 2
- 230000004438 eyesight Effects 0.000 description 2
- 208000001491 myopia Diseases 0.000 description 2
- 230000004379 myopia Effects 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 238000002604 ultrasonography Methods 0.000 description 2
- 208000002177 Cataract Diseases 0.000 description 1
- 206010020675 Hypermetropia Diseases 0.000 description 1
- 210000002294 anterior eye segment Anatomy 0.000 description 1
- 210000001742 aqueous humor Anatomy 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010291 electrical method Methods 0.000 description 1
- 230000004305 hyperopia Effects 0.000 description 1
- 201000006318 hyperopia Diseases 0.000 description 1
- 230000001678 irradiating effect Effects 0.000 description 1
- 230000000366 juvenile effect Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 210000003488 posterior eye segment Anatomy 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002207 retinal effect Effects 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/0008—Apparatus for testing the eyes; Instruments for examining the eyes provided with illuminating means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/14—Arrangements specially adapted for eye photography
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Abstract
An ophthalmic measuring system and method for detecting an eye to be inspected, the ophthalmic measuring system comprises a switching scanning element, an anterior segment optical path component, a posterior segment optical path component, a beam splitting element and a main body module, wherein the switching scanning element can be used for realizing the switching of an optical path between the anterior segment optical path component and the posterior segment optical path component and scanning the anterior segment and the posterior segment of the eye to be inspected. The invention provides another technical scheme capable of realizing the switching of the scanning of the front section and the back section of the eye to determine the axial length of the eye to be inspected, and can overcome the defects of complex structure and high cost in the prior art.
Description
Technical Field
The invention belongs to the field of ophthalmic examination equipment, and particularly relates to an ophthalmic measurement system and an ophthalmic measurement method.
Background
The effective prevention and treatment of cataract surgery, corneal refractive surgery, and juvenile myopia require accurate measurement of various parameters of the eye, such as anterior and posterior surface curvature of the cornea, corneal thickness, anterior chamber depth, lens thickness, anterior and posterior surface curvature of the lens, axial length of the eye, white-to-white distance, pupil diameter, etc. In the prior art, the most widely used technique for obtaining the plurality of parameters is the ultrasonic technique, but the measurement accuracy thereof is low.
In view of the drawbacks of the ultrasound technique, ophthalmic measurement systems based on OCT (Optical Coherence Tomography ) techniques have been developed for obtaining said plurality of parameters. OCT is an emerging optical imaging technology, has the advantages of high resolution, fast imaging speed, no radiation damage, compact structure, etc., and is an important potential tool for basic medical research and clinical diagnosis application. OCT techniques can be classified into TDOCT (Time Domain OCT) and FDOCT (Frequency Domain OCT ), which in turn can be further classified into ssooct (Swept Source OCT ) and SDOCT (Spectral Domain OCT, spectral Domain OCT). The ophthalmology measurement system is easy to realize based on the time domain OCT technology or the sweep source OCT technology, and the implementation difficulty of the technology based on the spectral domain OCT is high.
Chinese patent application number 200710020707.9 discloses a method for measuring the length of the eye axis, which is the length from the corneal vertex to the fovea of the macula, using time domain OCT. The method adopts a stepping motor to move the probe back and forth so as to realize the adjustment of the optical path, thereby imaging the cornea and the fundus, and has the following defects: 1) The imaging time required by the forward and backward movement of the stepping motor is long, real-time imaging cannot be performed, and a measured object can shake, blink and the like during the imaging period, so that the measured parameters such as the eye axis length and the like have larger errors; 2) The method can not carry out transverse scanning on eyes and can not judge the positions of the corneal vertex and the macula fovea, so that the measured eye axial length has larger difference with the actual eye axial length; 3) The cornea and retina have cornea, aqueous humor, lens, etc. organs, refract the light entering the eye, the method can not realize the focusing of the measurement light at the same time of cornea and retina, the imaging quality is poor.
In particular, ophthalmic measurement systems based on time domain OCT have the disadvantages of slow imaging speed, low measurement accuracy, poor image quality, etc., but the disadvantages of ultrasound technology are not overcome in practice. While the ophthalmic measurement system based on the sweep source OCT technology overcomes a plurality of defects of the ultrasonic technology, the ophthalmic measurement system is high in price and difficult to popularize.
Chinese patent publication No. CN103892791a discloses a system and method that can implement switching of anterior and posterior eye segment scans of an eye to be inspected to determine the eye axial length of the eye to be inspected based on spectral domain OCT techniques. However, the device adopts a plurality of switching mechanisms, and the switching mechanisms can be matched with each other to realize the switching of the scanning of the front section and the back section of the eye to be inspected, so that the device has a complex structure and is not easy to maintain; high cost and difficult popularization.
Disclosure of Invention
Based on the OCT technology, the invention provides an ophthalmic measurement system, belongs to another technical scheme capable of realizing the switching of the scanning of the front section and the back section of the eye to be inspected so as to determine the axial length of the eye to be inspected based on the spectral domain OCT technology, and can overcome the defects of complex structure and high cost in the prior art.
The technical scheme provided by the embodiment of the invention is as follows:
an ophthalmic measuring system for detecting an eye to be inspected comprises a switching scanning element, an anterior segment optical path component, a posterior segment optical path component, a beam splitting element and a main body module,
The light splitting element is arranged at one end close to the detected eye and is used for splitting anterior ocular segment signal light scattered by anterior ocular segment of the detected eye into first anterior ocular segment signal light and second anterior ocular segment signal light or splitting posterior ocular segment signal light scattered by posterior ocular segment of the detected eye into first posterior ocular segment signal light and second posterior ocular segment signal light;
The anterior ocular segment optical path component and the posterior ocular segment optical path component are arranged between the light splitting element and the switching scanning element, the anterior ocular segment optical path component is used for transmitting the first anterior ocular segment signal light to the switching scanning element, and the posterior ocular segment optical path component is used for transmitting the second posterior ocular segment signal light to the switching scanning element;
The switching scanning element is arranged at the other end opposite to the light splitting element, has a first working position and a second working position and can be switched between the first working position and the second working position, the switching scanning element can rotate in the first working position, the switching scanning element can rotate in the second working position,
The switching scanning element is positioned at the first working position and is used for transmitting the first anterior ocular segment signal light to the main body module, the switching scanning element rotates in the first working position to realize the scanning of the anterior ocular segment of the checked eye,
The switching scanning element is positioned at the second working position and is used for transmitting the second posterior segment signal light to the main body module, and the switching scanning element rotates in the second working position so as to realize scanning of the posterior segment of the eye to be inspected;
the main body module is used for interfering the first anterior ocular segment signal light and the second posterior ocular segment signal light and collecting corresponding interference light.
The embodiment of the invention also provides an ophthalmic measurement method for detecting an eye to be inspected, which comprises the following steps:
when the eye front section imaging is switched to, the eye to be inspected is irradiated by incident light, the front section signal light formed by scattering the incident light by the front section of the eye to be inspected is divided into first front section signal light and second front section signal light by using a light splitting element, the first front section signal light enters a front section light path component, the rotation angle of a switching scanning element is controlled, the switching scanning element is positioned at a first working position and rotates in the first working position, and the front section of the eye to be inspected is scanned and a series of first front section signal lights are received;
when the optical imaging device is switched to the back eye section imaging, the eye to be inspected is irradiated by incident light, the back eye section signal light formed by scattering the incident light by the back eye section of the eye to be inspected is divided into first back eye section signal light and second back eye section signal light by using a light splitting element, the second back eye section signal light enters a back eye section light path component, the rotation angle of a switching scanning element is controlled, the switching scanning element is positioned at a second working position and rotates in the second working position, and the back eye section of the eye to be inspected is scanned and a series of second back eye section signal lights are received;
Generating an anterior ocular segment OCT image of the eye to be inspected according to the series of first anterior ocular segment signal lights, generating a posterior ocular segment OCT image of the eye to be inspected according to the series of second posterior ocular segment signal lights, and calculating an eye axial length of the eye to be inspected according to the first anterior ocular segment signal lights and the second posterior ocular segment signal lights;
Checking the eye axial length according to the eye anterior segment OCT image and the eye posterior segment OCT image.
The ophthalmic measuring system and the ophthalmic measuring method provided by the embodiment of the invention are used for rapidly switching the anterior ocular segment imaging or the posterior ocular segment imaging of the eye to be inspected by controlling the rotation angle of the switching scanning element, and obtaining the related parameters of the eye to be inspected by calculating the optical path difference between the anterior ocular segment imaging and the posterior ocular segment imaging; and the switching scanning element also has a scanning function, so that the scanning of the anterior segment and the posterior segment of the eye to be inspected can be realized. Compared with the prior art, the invention provides another technical scheme capable of realizing the switching of the scanning of the front section and the back section of the eye to be inspected so as to determine the axial length of the eye to be inspected based on the spectral domain OCT technology, and meanwhile, the defects of complex structure and high cost of the prior art can be overcome.
Drawings
Fig. 1 is a schematic block diagram of an ophthalmic measurement system according to an embodiment of the present invention.
Fig. 2 is a schematic diagram of the ophthalmic measurement system of fig. 1.
Fig. 3 is a schematic diagram illustrating an operation principle of the switching scan element in fig. 2.
Fig. 4 (a) to 4 (b) are timing diagrams of the switching scan element and the detector in fig. 2.
Fig. 5 is a schematic diagram showing the distribution of the illumination lamps in the illumination light source in fig. 2.
The reference symbols in the figures are as follows:
main body module 100
Light source 101
Coupler 103
Detector 105
Reference arm assembly 130
Reference arm lens 131
Reference arm mirror 133
Polarization controller 107
Focusing lens 109
Controller 111
Switching scanning element 30
First working position 30a
Second working position 30b
Anterior ocular segment optical path assembly 50
First relay lens 51
Total reflection mirror 53
Second relay lens 55
Posterior segment optic path assembly 70
Optical path length adjusting unit 71
First reflecting mirror 71a
Second reflecting mirror 71c
Third reflecting mirror 71e
Fourth reflecting mirror 71g
Refractive adjustment element 73
Light splitting element 90
Eye objective 13
Fixation optical module 300
Fixation light source 301
Fixation lens 303
Anterior ocular segment camera module 500
Illumination source 501
Lighting lamp 501a
Spectroscope 502
First vision expanding lens 503
Fifth mirror 505
Second magnifier lens 507
First imaging lens 509
Second image pickup lens 511
Video camera 513
Detailed Description
The following description of the embodiments of the present invention will be made apparent and fully in view of the accompanying drawings, in which some, but not all embodiments of the invention are shown. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Embodiments of the present invention provide an ophthalmic measurement system (hereinafter referred to as "system") for detecting an eye E to be inspected, thereby determining a plurality of parameters of the eye E to be inspected, such as an axial length of the eye E to be inspected, a corneal curvature, an anterior chamber depth of the eye, a white-to-white distance, a pupil diameter, and the like. The system is based on the OCT technology, and as one of a plurality of technical effects of the system, the system can realize that the spectral domain OCT technology is applied to measuring the axial length of the eye to be inspected, but obviously, the system can also be applied to the time domain OCT technology and the sweep source OCT technology.
The following is only illustrative of the spectral domain OCT-based technique, and one of ordinary skill in the art can modify it without the need for creative effort to obtain a solution based on the time domain OCT technique and the swept source OCT technique.
Referring to fig. 1 and 2, the system includes a main body module 100, a switching scanning element 30, an anterior ocular segment optical path assembly 50, a posterior ocular segment optical path assembly 70, a beam splitting element 90, and an objective lens 13. The dashed line in the figure illustrates an optical path, the main body module 100 generates reference light and provides the switching scanning element 30 with incident light, the incident light is transmitted to the anterior ocular segment optical path assembly 50 or the posterior ocular segment optical path assembly 70 according to the rotation angle of the switching scanning element 30, and is reflected or transmitted by the light splitting element 90, and is focused to a corresponding part of the eye to be inspected E through the objective lens 13, and is scattered by the eye to be inspected E to form signal light, the signal light propagates back to the main body module 100 along a direction opposite to the incident light and interferes with the reference light to generate interference light, and the main body module 100 also collects the interference light.
Referring in detail to fig. 2, in an embodiment of the present invention, the body module 100 includes a light source 101, a coupler 103, a reference arm assembly 130, a detector 105, a polarization controller 107, a focus lens 109, and a controller 111. The reference arm assembly 130 further includes a reference arm lens 131 and a reference arm mirror 133. The light source 101 may be an OCT light source, which emits weak coherent light with a wavelength of near infrared, and transmits the weak coherent light to the coupler 103, and the coupler 103 divides the received light into two beams, wherein one beam is focused by the reference arm lens 131 and reflected by the reference arm mirror 133, and then returns to the coupler 103 to be used as reference light. The other beam is sequentially focused by the polarization controller 107 and the focusing lens 109 and then transmitted to the switching scanning element 30 as incident light.
Referring to fig. 3, in the embodiment of the present invention, the switching scan element 30 has a first working position 30a and a second working position 30b and is switchable between the first working position 30a and the second working position 30 b. The dashed lines illustrate the optical paths, and the direction of propagation of the incident light may be selected by controlling the switching scan element 30 to be at different angles of rotation so that the incident light is delivered to either the anterior ocular segment optical path assembly 50 or the posterior ocular segment optical path assembly 70. Specifically, the switching scanning element 30 is controllable to switch between the first working position 30a and the second working position 30b, and when the switching scanning element 30 is in the first working position 30a, incident light is transmitted to the anterior ocular segment optical path component 50; when the switching scan element 30 is in the second operational position 30b, incident light is delivered to the posterior segment optical path assembly 70.
Specifically, in an embodiment of the present invention, the system further includes an electronic control component (such as a motor), where the electronic control component has an electronically controlled rotating support (such as a rotating shaft), the electronic control component is electrically connected to the controller 111, the switching scanning element 30 is fixed on the electronically controlled rotating support, and the controller 111 controls the rotation of the electronic control component to drive the electronically controlled rotating support to rotate, so as to control the rotation angle of the switching scanning element 30, when the switching scanning element 30 rotates to the first working position 30a, the electronic control component reflects the incident light to the anterior ocular segment optical path component 50, and when the switching scanning element 30 rotates to the second working position, the electronic control component reflects the incident light to the posterior ocular segment optical path component 70.
It will be appreciated that in other embodiments of the present invention, the system may also control the angle of rotation of the switching scan element 30 by manual adjustment, and in particular, the system includes a rotating bracket for securing the switching scan element 30, the rotating bracket providing a knob by which the angle of rotation of the switching scan element 30 is adjusted manually to inject the incident light into the corresponding location of the eye E being inspected.
It is understood that in other embodiments of the present invention, the switching scan element 30 may be further controlled by other mechanical devices or electrical methods to perform angular rotation, and the design scheme meeting such design structure is within the scope of the present invention and will not be described herein.
In an embodiment of the present invention, the incident light reaches the light splitting element 90 after passing through the anterior ocular segment optical path component 50 or the posterior ocular segment optical path component 70, and the light splitting element 90 is specifically a half-mirror, which can transmit the incident light transmitted by the anterior ocular segment optical path component 50 and reflect the incident light transmitted by the posterior ocular segment optical path component 70. Specifically, in the embodiment of the present invention, when the switching scan element 30 is at the first working position 30a, the incident light passes through the beam splitter element 90 and is focused to the anterior ocular segment of the eye E, such as the cornea of the eye E, via the objective lens 13. When the switching scanning element 30 is at the second working position 30b, the incident light is reflected by the light splitting element 90 and focused to the posterior segment of the eye E, such as the retina of the eye E, via the objective lens 13.
It should be noted that, in the embodiment of the present invention, the anterior ocular segment optical path assembly 50 includes a total reflection mirror 53, and when the switching scan element 30 is in the first working position 30a, the total reflection mirror 53 reflects the light transmitted by the switching scan element 30 to the light splitting element 90.
It should be noted that, in the embodiment of the present invention, the anterior ocular segment optical path assembly 50 further includes at least one relay lens, where there is at least one relay lens between the switching scanning element 30 and the total reflection mirror 53, and when the switching scanning element 30 rotates to the first working position 30a, incident light is emitted to the total reflection mirror 53 through the relay lens; or at least one relay lens is provided between the total reflection mirror 53 and the spectroscopic element 90, and at this time, the total reflection mirror 53 reflects the incident light to the spectroscopic element 90 through the relay lens.
Preferably, in the embodiment of the present invention, the anterior ocular segment optical path assembly 50 comprises two relay lenses, namely a first relay lens 51 and a second relay lens 55, wherein the first relay lens 51 is between the total reflection mirror 53 and the switching scanning element 30, and the second relay lens 55 is between the total reflection mirror 53 and the beam splitting element 90. At this time, when the switching scanning element 30 is in the first working position 30a, the incident light is emitted to the total reflection mirror 53 through the first relay lens 51, reflected by the total reflection mirror 53, transmitted through the second relay lens 55, and then irradiated to the spectroscopic element 90.
In the embodiment of the present invention, the light splitting element 90 receives the incident light from the anterior ocular segment light path assembly 50, and the incident light is transmitted through the light splitting element 90 and focused onto the anterior ocular segment of the eye E, such as the cornea of the eye E, via the objective lens 13. The anterior ocular segment scatters the incident light to generate anterior ocular segment signal light, and the anterior ocular segment signal light is irradiated to the spectroscopic element 90 through the objective lens 13. The anterior ocular segment signal light is split into a first anterior ocular segment signal light and a second anterior ocular segment signal light by the light splitting element 90, and the second anterior ocular segment signal light is reflected by the light splitting element 90 to enter the posterior ocular segment light path component 70 and no longer propagates back to the main body module 100; the first anterior segment signal light propagates back to the main body module 100 through the light splitting element 90, the anterior segment optical path component 50, and the switching scanning element 30 in sequence along the direction opposite to the incident light, and interferes with the reference light in the coupler 103 to generate interference light, and the detector 105 receives and processes the interference light and transmits the interference light to the controller 111. Since the polarization direction of the first-eye front section signal light is controlled by the polarization controller 107 before returning to the coupler 103, the effect of interference is ensured.
In the embodiment of the present invention, the posterior segment optical path assembly 70 includes an optical path adjusting unit 71 and a refractive adjusting element 73, where the optical path adjusting unit 71 includes two fixed mirrors, a movable mirror group, and a displacement control element (not shown), the movable mirror group is fixed on the displacement control element, the fixed mirrors are a first mirror 71a and a second mirror 71c, and the movable mirror group includes a third mirror 71e and a fourth mirror 71g. When the switching scanning element 30 is at the second working position 30b, it transmits the incident light to the first mirror 71a in the optical path adjusting unit 71, and reflects the incident light to the refraction adjusting element 73 through the third mirror 71E, the fourth mirror 71g and the second mirror 71c, and the incident light is transmitted to the light splitting element 90 after transmitted through the refraction adjusting element 73, and reflected by the light splitting element 90 through the objective lens 13, and finally focused on the posterior ocular segment of the eye E.
In measuring the posterior segment of the eye E, since the axial length of the eye E is different from one eye E to another, it is necessary to provide an optical path adjusting means in one of the anterior segment optical path block 50 and the posterior segment optical path block 70, and it is preferable to provide an optical path adjusting means in the posterior segment optical path block 70. In the embodiment of the present invention, the optical path adjusting unit includes four mirrors, two of which are fixed and the other two of which are movable, namely, the first mirror 71a and the second mirror 71c are fixed, the third mirror 71e and the fourth mirror 71g are movable, and the third mirror 71e and the fourth mirror 71g are fixed on the displacement control member, and when the optical path adjustment is realized, only two of the mirrors need to be kept fixed, namely, the first mirror 71a and the second mirror 71c are kept fixed, and at the same time, the other two mirrors are moved by the displacement control member, namely, the third mirror 71e and the fourth mirror 71g are moved up and down, so that the optical path adjustment can be realized. The displacement control element is provided with a displacement sensor for obtaining the displacement of the third mirror 71e and the fourth mirror 71 g. Preferably, in order to match with the fixation optical module provided in this embodiment, the first mirror 71a and the second mirror 71c are arranged in a staggered manner, the second mirror 71c is a dichroic mirror, and the first mirror 71a, the third mirror 71e and the fourth mirror 71g are all mirrors.
It is understood that in other embodiments of the present invention, the displacement of the second reflecting mirror 71c and the third reflecting mirror 71e may be calculated by a stepper motor, a voice coil motor, a grating ruler, a capacitive grating ruler, etc., and is not limited to the above-mentioned moving device or sensor, as long as the structure satisfying the design is within the scope of the present invention.
It will be appreciated that in other embodiments of the present invention, the movable mirror assembly may be a movable retro-reflector, and the optical path adjustment may be achieved by moving the movable retro-reflector while only holding the first and second mirrors 71a, 71c stationary.
In addition, in making posterior segment measurements, the position at which the incident light is focused within the eye E may be adjusted by the refractive adjustment element 73, such as by moving the refractive adjustment element 73 to focus light on the retina of the eye E, to achieve measurements of the eye E having myopia or hyperopia. In particular, the refractive adjustment element 73 is fixed to a translation device (not shown) whose movement can be controlled manually or electrically to achieve the refractive adjustment.
In the embodiment of the present invention, after the incident light is focused to the posterior segment of the eye E to be inspected, the posterior segment scatters the incident light and generates posterior segment signal light, and the posterior segment signal light is irradiated to the spectroscopic element 90 through the objective lens 13. The posterior segment signal light is split into a first posterior segment signal light and a second posterior segment signal light by the light splitting element 90, and the first posterior segment signal light is transmitted into the anterior segment optical path component 50 by the light splitting element 90 and does not propagate back to the main body module 100; the second posterior segment signal light is reflected by the light splitting element 90, and then propagates back to the main body module 100 through the posterior segment optical path component 70 and the switching scanning element 30 in sequence along the direction opposite to the incident light, and interferes with the reference light in the coupler 103 to generate interference light, and the detector 105 receives and processes the interference light and transmits the interference light to the controller 111. Since the polarization direction of the second posterior segment signal light is controlled by the polarization controller 107 before returning to the coupler 103, the effect of interference is ensured. The controller 111 obtains the parameters corresponding to the eye E to be inspected by the optical path difference between the anterior segment imaging and the posterior segment imaging.
In addition, in the embodiment of the present invention, the switching scanning element 30 may perform rapid switching of the optical path, and may perform scanning imaging on the eye E. The switching scanning element 30 is rotatable in the first working position 30a to scan the anterior segment of the eye E, and the switching scanning element 30 is rotatable in the second working position 30b to scan the posterior segment of the eye E.
Referring to fig. 4 (a) to 4 (b), the switching scan element 30 starts to rotate from the initial position 1, t 1 is the working time required to scan the anterior segment or the posterior segment of the eye E, t 2 is the time required to switch the switching scan element 30 from anterior segment imaging to posterior segment imaging, and t 3 is the time required to return the switching scan element 30 to the initial position 1 after the posterior segment of the eye E is scanned. The "anterior segment scanning position" is a position where the switching scanning element 30 is in the first operating position 30a such that the incident light is focused on the anterior segment of the eye E. The "posterior segment position" is a position where the switching scan element 30 is in the second operating position 30b such that the incident light is focused on the posterior segment of the eye E.
When an anterior ocular segment image is to be acquired, the switching scan element 30 is rotated within the first operating position 30a while the detector 105 simultaneously begins to acquire signals. When the time t 1 passes, the switching scan element 30 is in position 2. After the detector 105 acquires the anterior ocular segment image, the switching scan element 30 is switched to the second working position 30b, and the time required for this process is t 2, and the switching scan element 30 reaches position 3.
The acquisition of an image of the posterior segment of the eye is then initiated, and the switching scan element 30 is rotated within the second operating position 30b while the detector 105 simultaneously initiates the acquisition of signals. When the time t 1 passes, the switching scan element 30 is in position 4. After the detector 105 acquires the posterior segment image, the switching scan element 30 rotates in the opposite direction to return to the initial position 1, and the time required for this process is t 3, and the switching scan element 30 returns to the initial position 1.
In the embodiment of the present invention, the controller 111 controls the state change and the time of the switching scan element 30 and the detector 105.
In an embodiment of the invention, the system further comprises a fixation optical module 300, the fixation optical module 300 comprising a fixation light source 301 and a fixation lens 303. The light emitted by the fixation light source 301 is visible light, the fixation light source 301 is specifically a display screen, and the display screen can be an LCD screen, an OLED screen, an LED array screen, or the like, for displaying a fixation mark for fixation of the eye E.
In the posterior segment optical path assembly 70, the first mirror 71a and the second mirror 71c are disposed in a staggered manner, and in the embodiment of the present invention, the second mirror 71c is a dichroic mirror. Specifically, the second reflecting mirror 71c is transparent to the light outputted from the fixation light source 301 and reflects the incident light transmitted from the switching scanning element 30.
The light emitted from the fixation light source 301 is transmitted through the fixation lens 303 and the second reflecting mirror 71c, is bent by the refraction adjusting element 73, is reflected by the light splitting element 90, and is focused by the objective lens 13 onto the posterior segment of the eye E, such as the retina of the eye E.
Specifically, in the embodiment of the present invention, the fixation position of the eye E may be changed by using a fixation mark, and the fixation mark may be moved up and down and left and right, so as to satisfy detection of different positions of the eye. The diopter of the light emitted by the fixation light source 301 can be adjusted by the diopter adjusting element 73, if the light emitted by the fixation light source 301 cannot be adjusted, the sharpness of the fixation mark is different when the eye E with different vision is observed, which makes the eye feel uncomfortable when the eye is fixed, so that it is preferable that the optical path emitted by the fixation light source 301 can be focused on the fundus retina after being adjusted by the diopter adjusting element 73, so that the eye can see the sharpness of the fixation mark.
In order to achieve the effect that different eyes E can see the clear fixation marks, the refraction adjusting element 73 introduces a refraction adjusting mechanism into the fixation optical module 300, so that the effect that the eyes E can see the clear fixation marks is achieved. If a fixation optical module is added directly after the refractive adjustment element 73, i.e., the fixation optical module is added to the other end of the refractive adjustment element 73 with respect to the optical path adjustment unit 71, the optical path at the time of imaging the posterior segment of the eye is affected. For example, if a fixation optical module is added between the refraction adjusting element 73 and the optical path adjusting unit 71, a beam splitter needs to be additionally introduced, and the light emitted by the fixation light source is reflected to the refraction adjusting element 73 by the beam splitter, so that the incident light and the signal light need to transmit the beam splitter, energy is lost, and the signal-to-noise ratio is reduced; for example, if a fixation optical module is added between the optical path adjusting unit 71 and the switching scanning element 30, not only a new beam splitter needs to be added, but also the fixation mark is caused to move along with the four mirrors in the optical path adjusting unit 71. In the embodiment of the present invention, the first mirror 71a and the second mirror 71c in the optical path adjusting unit 70 are arranged in a staggered manner, and the second mirror 71c is configured as a dichroic mirror, so that the incident light transmitted from the switching scanning element 30 can be reflected by the light output by the fixation light source 301, thereby not only realizing clear fixation of the fixation target by the eye E, but also not affecting the optical path during imaging of the posterior segment of the eye.
It should be noted that, the system provided in the embodiment of the present invention further includes an anterior segment photographing module 500 for photographing an image required for determining parameters such as a central curvature of cornea, a pupil diameter, a white-to-white distance, etc. of the eye E, for example, an iris image of the eye E. The anterior ocular segment camera module 500 is electrically connected to the controller 111, and comprises: an illumination light source 501, a beam splitter 502, a magnifying lens group, a fifth reflecting mirror 505, an imaging lens group, and an imaging device 513. Specifically, the illumination light source 501 is disposed between the objective lens 13 and the eye to be inspected E, and the illumination light source 501 emits near infrared light. The beam splitter 502 is a dichroic mirror, and transmits light outputted from the illumination light source 501 and reflects light outputted from the light source 101 and light outputted from the fixation light source 301.
The light emitted by the illumination light source 501 irradiates the anterior segment of the eye to be inspected E, and is reflected by the anterior segment to form reflected light, wherein a part of the light is reflected by the cornea of the eye to be inspected E, and a part of the light enters the eye to be inspected E through the cornea and is diffusely reflected by tissues such as the anterior chamber of the eye to be inspected E.
In the embodiment of the present invention, the magnifying lens group is used for converging the reflected light, and includes a first magnifying lens 503 and a second magnifying lens 507; the image pickup lens group is for imaging the reflected light on the image pickup device, and includes a first image pickup lens 509 and a second image pickup lens 511.
The reflected light is transmitted to the fifth reflecting mirror 505 through the objective lens 13, the beam splitter 502 and the first magnifying lens 503, is reflected by the fifth reflecting mirror 505, passes through the second magnifying lens 507, the first image capturing lens 509 and the second image capturing lens 511, and is focused by the first image capturing lens 509 and the second image capturing lens 511 onto the camera 513 to form an image of the front section of the eye to be inspected, and the controller 111 collects the image of the front section of the eye to be inspected.
In order to make the subject feel comfortable, the contact lens 13 is set to protrude from the system so as to avoid a sense of pressure caused by contact with the system, and thus the distance between the contact lens 13 and the camera 513 is large. In order to determine parameters such as white-to-white distance, the anterior ocular segment imaging module needs to have a large imaging range, which is contradictory to the anterior ocular segment imaging module's 13 extension. The object of the present invention is to solve the above-mentioned contradiction, and the first and second magnifier lenses 503 and 507 can change the propagation directions of the light reflected by the cornea and the light diffusely reflected by the anterior chamber to converge, and finally form a wide-range image on the camera 513.
Referring to fig. 5, in the embodiment of the invention, the illumination light source 501 includes a plurality of illumination lamps 501a, the plurality of illumination lamps 501a are uniformly distributed in an annular array, and when the system is in a keratometry working condition, the geometric center of the annular shape formed by the illumination lamps 501a is aligned with the pupil center of the eye E to be inspected. Specifically, the number of the illumination lamps 501a is 4 or more, and preferably, in the embodiment of the present invention, the number of the illumination lamps 501a is 6.
When the system is in the cornea curvature measuring working condition, the light emitted by the 6 illumination lamps 501a irradiates the cornea of the eye to be detected E, the light is reflected by the cornea, the reflected light passes through the anterior chamber imaging module 500 and is finally detected by the camera 513, and a distribution image of the 6 illumination lamps 501a on the cornea is formed on the camera 513. In an embodiment of the invention, the distribution image is formed together with an image of the anterior segment of the eye to be inspected.
The controller 111 acquires images of the distribution of the 6 illumination lamps 501a on the cornea, processes the images using an algorithm installed therein, and obtains the cornea curvature of the eye E to be inspected, and in the embodiment of the present invention, the controller 111 obtains the cornea center curvature of the eye E to be inspected.
In the embodiment of the invention, the anterior ocular segment photographing module 500 further has the function of monitoring the optical path to guide the operator to operate the instrument and know the related information of the tested person, the system is movably arranged on an operation table, a jaw support system is arranged on the operation table, the tested person uses the jaw support system to fix the tested person E, after the fixation mark from the fixation optical module 300 is fixed in the tested person E, the tester controls the movement of the jaw support system and the ophthalmic measuring system through the operation rod while observing the display screen of the controller 111, so that the anterior ocular segment of the tested person E, such as the iris, enters the camera 513 of the anterior ocular segment photographing module 500, and the iris image is presented in the display screen of the controller 111, so as to guide the doctor to operate the instrument and know the related information of the tested person E.
In summary, in the ophthalmic measurement system provided by the embodiment of the present invention, the rotation angle of the switching scanning element 30 is controlled to rapidly switch the anterior segment imaging or the posterior segment imaging of the eye E to be inspected, and the optical path difference between the anterior segment imaging and the posterior segment imaging is calculated to obtain the relevant parameters of the eye E to be inspected; and the switching scanning element 30 also has a scanning function, and can realize scanning of the anterior ocular segment and the posterior ocular segment of the eye E to be inspected. Compared with the prior art, the invention provides another technical scheme capable of realizing the switching of the scanning of the front section and the back section of the eye to be inspected so as to determine the axial length of the eye to be inspected based on the spectral domain OCT technology, and meanwhile, the defects of complex structure and high cost of the prior art can be overcome.
The embodiment of the invention also provides an ophthalmic measurement method for detecting an eye to be inspected, which comprises the following steps:
S101, when the eye front section imaging is switched to, the eye to be inspected is irradiated by using incident light, the front section signal light formed by scattering the incident light by the front section of the eye to be inspected is divided into first front section signal light and second front section signal light by using a light splitting element, the first front section signal light enters a front section light path component, the rotation angle of a switching scanning element is controlled, the switching scanning element is positioned at a first working position and rotates in the first working position, and the front section of the eye to be inspected is scanned and a series of first front section signal lights are received;
specifically, when switching to anterior ocular segment imaging, the rotation of the switching scan element may be controlled by a computer to be in a first working position and rotated within the first working position.
The first anterior ocular segment signal light enters the anterior ocular segment optical path assembly such that the computer may receive the first anterior ocular segment signal light delivered by the anterior ocular segment optical path assembly to the switching scan element.
When switching to anterior segment imaging, the computer may first detect whether the anterior segment switching period is currently in the anterior-posterior segment switching acquisition timing, and when detecting the anterior segment switching period in the anterior-posterior segment switching acquisition timing, the computer may control the switching scanning element to rotate so that the switching scanning element is in the first working position. Thereafter, the computer may further continue to detect whether or not in the anterior ocular segment image collection period in the anterior ocular segment switching collection timing, and when detecting that the anterior ocular segment image collection period in the anterior ocular segment switching collection timing is detected, control the switching scanning element to scan the anterior ocular segment of the eye to be inspected to receive a series of first anterior ocular segment signal lights delivered by the anterior ocular segment optical path component, that is, all the processes in step S101 may be performed in the anterior ocular segment switching period and the anterior ocular segment image collection period. The time length of the anterior ocular segment switching period may be preset, and the time length of the anterior ocular segment image acquisition period may be preset according to the scanning time length of the anterior ocular segment of the eye to be inspected by the switching scanning element.
S102, when the eye is switched to the posterior segment imaging, the eye to be inspected is irradiated by using incident light, an optical splitting element is used for splitting posterior segment signal light formed by scattering the incident light of the eye posterior segment of the eye to be inspected into first posterior segment signal light and second posterior segment signal light, the second posterior segment signal light enters an posterior segment optical path component, the rotation angle of a switching scanning element is controlled, the switching scanning element is positioned at a second working position and rotates in the second working position, and the posterior segment of the eye to be inspected is scanned and a series of second posterior segment signal lights are received;
Specifically, when switching to posterior segment imaging, the computer may control the rotation of the switching scan element to be in the second working position and to rotate in the second working position.
The second posterior segment signal light enters the posterior segment optical path assembly so that the computer may receive the second posterior segment signal light delivered by the posterior segment optical path assembly to the switching scan element.
When switching to posterior segment imaging, the computer may detect whether the posterior segment switching period is currently in the anterior-posterior segment switching acquisition timing, and when detecting the posterior segment switching period in the anterior-posterior segment switching acquisition timing, the computer may control the switching scanning element to rotate so that the switching scanning element is in the second working position. Thereafter, the computer may further continue to detect whether or not in the posterior segment image collection period in the anterior-posterior segment switching collection timing, and when detecting the posterior segment image collection period in the anterior-posterior segment switching collection timing, control the switching scanning element to scan the posterior segment of the eye to be inspected to receive a series of second posterior segment signal lights transmitted by the posterior segment optical path component, that is, all the processes in step S102 may be performed in the posterior segment switching period and the posterior segment image collection period. The time length of the posterior segment switching period can be preset, and the time length of the posterior segment image acquisition period can be preset according to the scanning time length of the posterior segment of the eye to be detected by the switching scanning element.
S103, generating an eye anterior segment OCT image of the eye to be inspected according to the series of first eye anterior segment signal lights, generating an eye posterior segment OCT image of the eye to be inspected according to the series of second eye posterior segment signal lights, and calculating the eye axial length of the eye to be inspected according to the first eye anterior segment signal lights and the second eye posterior segment signal lights;
Specifically, the computer may generate an anterior ocular segment OCT image of the eye to be inspected from the series of first anterior ocular segment signal lights, generate a posterior ocular segment OCT image of the eye to be inspected from the series of second posterior ocular segment signal lights, and calculate an eye axial length of the eye to be inspected from the first anterior ocular segment signal lights and the second posterior ocular segment signal lights. When the first anterior ocular segment signal light is received, the first anterior ocular segment signal light can be interfered to obtain the interfered first anterior ocular segment signal light; when the second posterior segment signal light is received, the second posterior segment signal light can be interfered to obtain the interfered second posterior segment signal light, at this time, the computer can specifically obtain an anterior segment OCT image of the eye to be inspected according to a series of first anterior segment signal lights after interference, obtain an posterior segment OCT image of the eye to be inspected according to a series of second posterior segment signal lights after interference, and calculate an eye axial length of the eye to be inspected according to the first anterior segment signal light and the second posterior segment signal light.
S104, checking the axial length of the eye according to the OCT image of the anterior segment of the eye and the OCT image of the posterior segment of the eye;
specifically, the computer may check the eye axial length from the anterior ocular segment OCT image and the posterior ocular segment OCT image. The computer can judge whether the OCT image of the anterior segment of the eye has a central light column, and if the OCT image of the anterior segment of the eye has the central light column, the OCT image of the anterior segment of the eye comprises a cornea vertex; the computer can judge whether the post-ocular segment OCT image has a central light column, and if the post-ocular segment OCT image has a central light column, the post-ocular segment OCT image includes a macular fovea. The central light beam is formed by strong reflection of the corneal vertex and the macula fovea of the eye to be inspected in the process of scanning the eye to be inspected by incident light. If the anterior ocular segment OCT image comprises a corneal vertex and the posterior ocular segment OCT image comprises a macular fovea, determining that the axial length of the eye calculated by the computer coincides with the actual axial length of the eye to be inspected.
Wherein, S103, calculating the eye axis length of the eye to be inspected according to the first anterior segment signal light and the second posterior segment signal light may specifically include the following steps:
S103a, acquiring an optical path from the top end of the anterior ocular segment image to a cornea signal in the anterior ocular segment image according to the anterior ocular segment image generated by the interfered first anterior ocular segment signal light;
s103b, acquiring the optical path from the top end of the posterior segment image to the retina signal in the posterior segment image according to the posterior segment image generated by the second posterior segment signal light after interference;
S103c, calculating the length of the eye axis according to the optical path from the top end of the anterior segment image to the cornea signal in the anterior segment image, the optical path from the top end of the posterior segment image to the retina signal in the posterior segment image, the optical path adjustment quantity, the inherent optical path of the anterior segment optical path and the inherent optical path of the posterior segment optical path;
Specifically, the optical path from the top of the anterior segment image to the cornea signal in the anterior segment image may be specifically the distance from the top of the cornea in the anterior segment image to the top of the image, and the optical path from the top of the posterior segment image to the retina signal in the posterior segment image may be specifically the distance from the top of the image in the posterior segment image to the fovea of the macula. The computer can calculate the length of the eye axis according to the optical distance from the top end of the anterior segment image to the cornea signal in the anterior segment image, the optical distance from the top end of the posterior segment image to the retina signal in the posterior segment image, the optical distance adjustment amount, the inherent optical distance of the anterior segment optical path and the inherent optical distance of the posterior segment optical path, wherein the optical distance adjustment amount is the optical distance change amount generated when the imaging of the posterior segment image is adjusted.
The eye axis length is as follows: the inherent optical path of the anterior segment optical path, the inherent optical path of the posterior segment optical path, the optical path adjustment amount, the optical path from the top end of the posterior segment image to the retinal signal in the posterior segment image, and the optical path from the top end of the anterior segment image to the cornea signal in the anterior segment image.
The difference between the inherent optical path length of the anterior segment optical path and the inherent optical path length of the posterior segment optical path is a fixed optical path length difference of the anterior segment and the posterior segment, and the distance corresponding to the fixed optical path length difference of the anterior segment and the posterior segment can be obtained through calibration measurement.
In an embodiment of the invention, the ophthalmic measurement method further comprises:
S105, obtaining initial cornea curvature distribution of the detected eye according to the OCT image of the anterior segment of the eye;
Specifically, the scanning the anterior segment of the eye to be inspected includes performing multi-line scanning on the anterior segment, for example, performing six-line scanning or twelve-line scanning on the anterior segment. The six lines are six lines which are distributed in a central symmetry way by taking the corneal vertex as a symmetry center; the performing six-line scanning on the anterior ocular segment means scanning the anterior ocular segment along the six lines to obtain six OCT images of the anterior ocular segment.
And carrying out scanning correction and refraction correction on the six OCT images, and determining the curvature distribution of the cornea to obtain the initial cornea curvature distribution.
S106, irradiating the cornea of the eye to be inspected with light emitted by a plurality of illumination lamps which are uniformly distributed in a ring shape, so as to obtain a distribution image of the plurality of illumination lamps on the cornea;
Specifically, illuminating the cornea of the eye to be inspected with illumination light emitted by a plurality of illumination lamps uniformly distributed in a ring shape, so that the cornea reflects the illumination light to generate reflected light; receiving the reflected light by using a camera to form a distribution image of the plurality of illuminating lamps on the cornea;
And determining the distance from the plurality of illumination lamps to the cornea according to the first anterior segment signal light, and obtaining the central curvature of the cornea of the eye to be inspected according to the distribution image and the distance from the plurality of illumination lamps to the cornea, S109.
And S107, checking the initial cornea curvature distribution according to the cornea central curvature to obtain checked cornea curvature distribution.
Specifically, the curvature distribution of each point on the cornea is determined after the six OCT images of the anterior segment of the eye are subjected to scan correction and refraction correction, and because two steps of scan correction and refraction correction are required, the curvature distribution of each point on the cornea is determined to have a large error. Therefore, the curvature distribution of each point on the cornea is corrected by utilizing the central curvature of the cornea, so that the more accurate curvature distribution of each point on the cornea is obtained, and the checked cornea curvature distribution is obtained.
According to the embodiment of the invention, the rotation of the switching scanning element is controlled, so that the imaging of the anterior ocular segment or the imaging of the posterior ocular segment of the eye to be inspected can be rapidly switched, the anterior ocular segment signal light and the posterior ocular segment signal light are respectively collected, and the axial length of the eye is calculated through the anterior ocular segment signal light and the posterior ocular segment signal light; and the eye to be inspected can be scanned, and the eye anterior segment OCT image and the eye posterior segment OCT image of the eye to be inspected are obtained through scanning, so that the eye axial length is corrected by utilizing the eye anterior segment OCT image and the eye posterior segment OCT image. Another method for measuring the length of the eye axis is provided relative to the prior art, and the defect of complex operation in the prior art is overcome.
Claims (9)
1. An ophthalmic measuring system for detecting an eye to be inspected, comprising a switching scanning element, an anterior segment optical path component, a posterior segment optical path component, a light splitting element, an eye objective lens, a fixation optical module and a main body module, wherein the main body module comprises a light source, the posterior segment optical path component comprises an optical path adjusting unit and a refraction adjusting element, the fixation optical module comprises a fixation light source, and the optical path adjusting unit comprises a reflecting mirror, a dichroic mirror and a movable reflecting mirror group;
The reflecting mirror and the dichroic mirror are fixed, the movable reflecting mirror group is moved to adjust the optical path of light in the posterior ocular optical path component, the reflecting mirror and the dichroic mirror are arranged in a staggered mode, the dichroic mirror can reflect the light output by the light source and can transmit the light output by the fixation light source, and the light output by the fixation light source sequentially passes through the dichroic mirror and the refraction adjusting element to reach the light splitting element, and is reflected by the light splitting element and focused by the eye objective lens to the posterior ocular of the eye to be inspected;
The light splitting element is arranged at one end close to the detected eye and is used for splitting anterior ocular segment signal light scattered by anterior ocular segment of the detected eye into first anterior ocular segment signal light and second anterior ocular segment signal light or splitting posterior ocular segment signal light scattered by posterior ocular segment of the detected eye into first posterior ocular segment signal light and second posterior ocular segment signal light;
The anterior ocular segment optical path component and the posterior ocular segment optical path component are arranged between the light splitting element and the switching scanning element, the anterior ocular segment optical path component is used for transmitting the first anterior ocular segment signal light to the switching scanning element, and the posterior ocular segment optical path component is used for transmitting the second posterior ocular segment signal light to the switching scanning element;
The switching scanning element is arranged at the other end opposite to the light splitting element, has a first working position and a second working position and can be switched between the first working position and the second working position, the switching scanning element can rotate in the first working position, the switching scanning element can rotate in the second working position,
The switching scanning element is positioned at the first working position and used for transmitting the first anterior ocular segment signal light to the main body module, the switching scanning element rotates in the first working position to realize scanning of the anterior ocular segment of the checked eye, the switching scanning element is positioned at the second working position and used for transmitting the second posterior ocular segment signal light to the main body module, and the switching scanning element rotates in the second working position to realize scanning of the posterior ocular segment of the checked eye;
the main body module is used for interfering the first anterior ocular segment signal light and the second posterior ocular segment signal light and collecting corresponding interference light.
2. The system of claim 1, wherein the body module further comprises a coupler that receives light from the light source and provides light to the reference arm assembly and the switching scan element, and a reference arm assembly that reflects the received light back to the coupler to form reference light.
3. The system of claim 2, wherein the body module further comprises a detector and a controller, the detector being electrically connected to the controller, the first anterior ocular segment signal light or the second posterior ocular segment signal light interfering with the reference light within the coupler and forming an interference light, the interference light being received and processed by the detector and collected by the controller.
4. The system of claim 1, wherein when imaging the posterior segment of the eye to be inspected, the rotation angle of the switching scanning element is controlled such that the switching scanning element is in the second working position, the incident light provided by the switching scanning element sequentially passes through the optical path adjusting unit and the diopter adjusting element to reach the light splitting element, and is reflected by the light splitting element and focused by the objective lens to the posterior segment of the eye to be inspected, so as to generate the posterior segment signal light, and the second posterior segment signal light split from the posterior segment signal light returns to the main body module along an optical path opposite to the incident light.
5. The system of claim 1, further comprising an anterior ocular segment camera module, wherein the body module comprises a controller, wherein the anterior ocular segment camera module is electrically connected to the controller, wherein the anterior ocular segment camera module comprises an illumination source and a camera, wherein light emitted by the illumination source is reflected by the anterior ocular segment of the subject to form reflected light, wherein the reflected light enters the anterior ocular segment camera module and forms an image of the anterior ocular segment of the subject on the camera, and wherein the controller captures the image of the anterior ocular segment of the subject.
6. The system of claim 5, wherein the anterior ocular segment imaging module further comprises a magnifying lens assembly and an imaging lens assembly, the magnifying lens assembly and the imaging lens assembly disposed between the illumination source and the camera, the magnifying lens assembly configured to converge the reflected light, the imaging lens assembly configured to image the reflected light on the camera, the reflected light passing through the magnifying lens assembly and the imaging lens assembly to form an image of the anterior ocular segment of the inspected eye on the camera.
7. The system of claim 5, wherein the illumination source comprises a plurality of illumination lamps, the plurality of illumination lamps are uniformly distributed in an annular array, light emitted by the plurality of illumination lamps irradiates the cornea of the eye to be inspected and is reflected by the cornea to form reflected light, the reflected light enters the anterior segment imaging module and forms a distribution image of the illumination lamps on the cornea at the camera, and the controller collects the distribution image and obtains the cornea curvature of the eye to be inspected by using an algorithm installed inside the controller.
8. An ophthalmic measurement method for detecting an eye to be inspected, which is applied to the ophthalmic measurement system as claimed in claim 1, wherein the ophthalmic measurement system comprises a switching scanning element, an anterior segment optical path element, a posterior segment optical path element, a light splitting element, an objective lens, a fixation optical module and a main body module, the main body module comprises a light source, the posterior segment optical path element comprises an optical path adjusting unit and a refraction adjusting element, the fixation optical module comprises a fixation light source, the optical path adjusting unit comprises a reflecting mirror, a dichroic mirror and a movable reflecting mirror group, the reflecting mirror and the dichroic mirror are arranged in a dislocation manner, and the dichroic mirror can reflect light output by the light source and can transmit light output by the fixation light source;
When an eye to be inspected is detected, light output by the fixation light source sequentially passes through the dichroic mirror and the refraction adjusting element to reach the light splitting element, and is reflected by the light splitting element and focused by the eye receiving objective lens to an eye posterior segment of the eye to be inspected;
When the eye front section imaging is switched to, the eye to be inspected is irradiated by incident light, the front section signal light formed by scattering the incident light by the front section of the eye to be inspected is divided into first front section signal light and second front section signal light by using a light splitting element, the first front section signal light enters a front section light path component, the rotation angle of a switching scanning element is controlled, the switching scanning element is positioned at a first working position and rotates in the first working position, and the front section of the eye to be inspected is scanned and a series of first front section signal lights are received;
when the optical imaging device is switched to the back eye section imaging, the eye to be inspected is irradiated by incident light, the back eye section signal light formed by scattering the incident light by the back eye section of the eye to be inspected is divided into first back eye section signal light and second back eye section signal light by using a light splitting element, the second back eye section signal light enters a back eye section light path component, the rotation angle of a switching scanning element is controlled, the switching scanning element is positioned at a second working position and rotates in the second working position, and the back eye section of the eye to be inspected is scanned and a series of second back eye section signal lights are received;
Generating an anterior ocular segment OCT image of the eye to be inspected according to the series of first anterior ocular segment signal lights, generating a posterior ocular segment OCT image of the eye to be inspected according to the series of second posterior ocular segment signal lights, and calculating an eye axial length of the eye to be inspected according to the first anterior ocular segment signal lights and the second posterior ocular segment signal lights;
Checking the eye axial length according to the eye anterior segment OCT image and the eye posterior segment OCT image.
9. The method as recited in claim 8, further comprising:
Obtaining an initial corneal curvature distribution of the eye to be inspected according to the anterior ocular segment OCT image;
Illuminating the cornea of the eye to be inspected by utilizing light emitted by a plurality of illumination lamps which are annularly and uniformly distributed to obtain a distribution image of the illumination lamps on the cornea, and obtaining the central curvature of the cornea of the eye to be inspected according to the distribution image;
Checking the initial cornea curvature distribution according to the cornea center curvature to obtain checked cornea curvature distribution.
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| CN111643050A (en) * | 2020-06-10 | 2020-09-11 | 苏州比格威医疗科技有限公司 | Ophthalmic optical imaging system |
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| CN208677360U (en) * | 2018-02-08 | 2019-04-02 | 深圳市斯尔顿科技有限公司 | Ophthalmic measurement system |
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