CN116602309A - Agricultural composition containing fenoxycarb and organophosphorus pesticide - Google Patents

Abstract

The invention belongs to the technical field of pesticide compounding, and relates to an agricultural composition containing fenoxycarb and organophosphorus pesticides. The active ingredients include component A and component B, the component A is fenoxycarb, and the component B is an organophosphorus pesticide; the organophosphorus pesticide is selected from phoxim, malathion, quinathion and profenofos. Within a certain proportion range, the composition has excellent performance in preventing and controlling food crops and vegetable pests, especially has excellent insecticidal activity against agricultural Lepidoptera pests such as cotton bollworm, diamondback moth, cabbage caterpillar and noctuid. exhibit a synergistic effect.

Description

A kind of agricultural composition containing fenoxycarb and organophosphorus pesticide

technical field

The invention belongs to the technical field of pesticide compounding and relates to an agricultural composition containing fenoxycarb and organophosphorus pesticides.

Background technique

Fenoxycarb, its chemical name is 2-(p-phenoxyphenoxy) ethyl carbamate, it is a non-terpene carbamate compound, has stomach toxicity and contact action, and has As an insect growth regulator, it has a broad-spectrum insecticidal effect; however, its insecticidal effect is non-neurological, and it has a strong juvenile hormone activity on a variety of insects, which can lead to egg killing, inhibit the metamorphosis of adult stages and the growth of larvae. Moulting, resulting in the death of larvae or pupal stage, specific insecticide, harmless to bees and beneficial organisms. Fenoxycarb is mainly used in warehouses to prevent and control storage pests. Wells have the function of regulating insect growth, such as destroying the unique metamorphosis of insects, spraying barns to prevent the reproduction of Coleoptera and Lepidoptera pests, spraying indoor cracks to prevent cockroaches, fleas etc. It can be made into bait to control various ant colonies such as fire ants and termites. It can be used to prevent mosquito larvae from developing into adults in cotton fields, orchards, vegetable gardens and ornamental plants. It can effectively prevent and control psyllids, scales, leaf rollers, etc. It is also effective against pests that are resistant to the current commonly used pesticides.

Phoxim is an organophosphorus insecticide with high efficiency and low toxicity. It has stomach killing and contact killing effects, and is mainly used to control underground pests. Phoxim is an organophosphorus insecticide mainly used to prevent and control underground pests. It is suitable for pest control of crops such as peanuts, wheat, rice, cotton, and corn, and is also used to control pests such as fruit trees, vegetables, mulberry, and tea. Grubs, mole crickets, needleworms, etc. have good effects. Phoxim has a wide insecticidal spectrum, strong knockdown power, no systemic effect, and is very effective against Phosphoptera larvae. Phoxim is unstable to light in the field and decomposes quickly, so the residual period is short and the residual risk is small. However, when the drug is applied to the soil, the residual period is very long, which is suitable for controlling underground pests. It has a good effect on the larvae of various Lepidoptera pests that harm peanuts, wheat, rice, cotton, corn, fruit trees, vegetables, mulberry, tea and other crops, and has a certain killing effect on eggs. Also suitable for controlling warehouse and sanitation pests.

Malathion, also known as Marathon, 4049 Marathion, etc., is a highly efficient and low-toxic organic phosphorus contact insecticide, which has strong systemic effect and good contact killing, stomach toxicity and certain fumigation Function: After the pesticide contacts the pest, it quickly enters the insect body through osmosis and oxidizes into malaoxon, thereby quickly exerting its poisonous effect. Generally, the pest can be knocked down within a few minutes after spraying, effectively controlling the spread of locusts. When malathion enters the body of warm-blooded animals, it is hydrolyzed by carboxylesterase in the body, thus losing its toxicity, but its toxicity to humans, livestock and other warm-blooded animals is very low, and the residual period is short.

Quetiaphos is a broad-spectrum organophosphorus insecticide and acaricide. With its excellent dual functions of stomach toxicity and contact killing, it can control many stubborn and difficult pests. It is especially effective against pyrethroid pesticide-resistant pests. Quetiaphos can also control spider mite and other mite pests, and has certain ovicidal effect. Quetiaphos degrades quickly in plants, has a short residual effect period, and has low residual toxins, making it safe to use in fruits and vegetables. Quetiaphos has good permeability in plants, and is suitable for various crops such as rice, cotton, peanuts, citrus, vegetables and some tropical and subtropical fruit trees.

Profenofos is an acetylcholinesterase-inhibiting organophosphorus insecticide. It has good penetration on plant leaves, but it is not a systemic drug. It has strong contact, stomach poisoning and certain fumigation effects. Profenofos is used to control various pests of cotton, vegetables, fruit trees and other crops, especially the control effect of resistant cotton bollworm is excellent.

Insecticide varieties containing a single active ingredient often have different degrees of defects in the control of agricultural pests, such as: narrow insecticidal spectrum, pests are prone to resistance after continuous use, and frequent use will aggravate environmental pollution. The combination of active ingredients with different mechanisms of action can effectively overcome the above shortcomings. At the same time, the synergistic effect produced by mixing multiple active components can improve the control effect, expand the insecticidal spectrum, delay the generation of pest resistance, and reduce environmental pollution. It is an important means of comprehensive pest control. However, in most cases, the compound effects of pesticides are additive, and there are fewer compounds showing synergistic effects, especially those with very obvious synergistic effects and high co-toxicity coefficients. However, there is no report about the compounding of fenoxycarb and organophosphorus pesticides.

Contents of the invention

The object of the present invention is to provide an agricultural composition containing fenoxycarb and organophosphorus pesticides, the active ingredients of which are fenoxycarb and organophosphorus pesticides compounded according to a specific ratio, and the action mechanisms of these pesticides are different , by verifying that their combination produces a good synergistic effect, expands the insecticidal spectrum, slows down the generation of drug resistance, improves the insecticidal effect, and is conducive to the sustainable development of the environment.

Based on the above purpose, the present invention provides an agricultural composition containing fenoxycarb and organophosphorus pesticides, its active ingredients include component A and component B, the component A is fenoxycarb, and the component B It is an organophosphorus pesticide; the organophosphorus pesticide is selected from phoxim, malathion, quinathion and profenofos.

Those of ordinary skill in the art are easy to know that to improve the efficacy of agricultural compositions and avoid the occurrence of drug resistance, multiple pesticides are used in combination or in combination. However, due to the unknown components and internal mechanisms, multiple pesticides are used in combination. Or whether the control effect after combined use is synergistic is difficult to predict. After in-depth experiments and explorations, the inventors found that the agricultural composition of the present invention has excellent control effects on lepidopteran pests, and is better than that of a single agent.

Furthermore, in the agricultural composition provided by the present invention, the active ingredients include fenoxycarb and phoxim; in terms of mass ratio, the ratio of fenoxycarb and phoxim is 7-18:1.

Furthermore, in the agricultural composition provided by the present invention, the active ingredients include fenoxycarb and malathion; in terms of mass ratio, the ratio of fenoxycarb and malathion is 1-9:1.

Furthermore, in the agricultural composition provided by the present invention, the active ingredients include fenoxycarb and quinalphos; in terms of mass ratio, the ratio of fenoxycarb and quinalphos is 1:6-24.

Further, in the agricultural composition provided by the present invention, the active ingredients include fenoxycarb and profenofos; in terms of mass ratio, the ratio of fenoxycarb and profenofos is 1:14-31.

Further, in the agricultural composition provided by the present invention, the active ingredients include fenoxycarb, phoxim and malathion; in terms of mass ratio, the ratio of fenoxycarb, phoxim and malathion is 11～19:3～12:1.

Further, in the agricultural composition provided by the present invention, the active ingredients include fenoxycarb, quinalfos and profenofos; in terms of mass ratio, the ratio of fenoxycarb, quetiafos and profenofos is 3～ 13:1:26-39.

According to actual application requirements, the composition of the present invention can be prepared into one of dosage forms such as aqueous emulsion, microemulsion, wettable powder, and water-dispersible granule according to methods known to those skilled in the art. The functional composition also contains auxiliary agents required for the preparation of pesticide formulations, auxiliary agents can be solvents, emulsifiers, wetting agents, stabilizers, dispersants, thickeners, pH regulators, defoamers, antifreeze One or a combination of agents, fillers, etc. The adjuvants described in the present invention can be all known substances, such as various adjuvants commonly used in pesticide preparations, which can vary according to different situations.

The method of application can be spraying, root irrigation, root soaking, seed soaking, watering, throwing, spreading, furrow application, hole application, etc. Spray treatment is preferred when controlling pests, and the preferred formulation for controlling pests is microemulsion.

The present invention also provides a method for preparing fenoxycarb and organophosphorus pesticides into microemulsions. The microemulsions are composed of the following components in weight percent: 20% to 40% of active ingredients, 10% to 20% of solvents and co-solvents, and 10% of emulsifiers ～20%, penetrant 1～5%, water make up 100%.

Put the fenoxycarb and organophosphorus pesticides in the above weight ratio into the solvent and co-solvent to dissolve them all, add a certain proportion of emulsifier and penetrant to the preparation kettle to make the oil phase, and stir at 1000-6000 rpm Slowly inject deionized water to make up to 100%, and after passing the inspection, a transparent microemulsion is prepared.

The composition of the present invention is mainly used for preventing and controlling pests in food crops and vegetables, and the pests are preferably Lepidoptera pests, such as cotton bollworm, diamondback moth, cabbage caterpillar, noctuid and the like.

Compared with the prior art, the technical solution provided by the present invention has the following beneficial effects or advantages:

Compared with the prior art, the main contribution of the present invention is to provide an agricultural composition containing fenoxycarb and organophosphorus pesticides, the active ingredients include component A and component B, the component A is fenoxycarb, The component B is an organophosphorus pesticide; the organophosphorus pesticide is selected from phoxim, malathion, quinathion and profenofos; the composition has an excellent control effect on plant pests. The inventor of this patent conducted a field drug efficacy test on the composition and found that within the given ratio range of the present invention, the composition has a better control effect on plant pests than a single dose, indicating that the combination has a synergistic effect .

Detailed ways

In the following, the technical solution of the present invention will be described in conjunction with examples, but the present invention is not limited to the following examples.

Example 1

This example provides an indoor joint toxicity test of an agricultural composition containing fenoxycarb and an organophosphorus pesticide against diamondback moth.

Test worms: third-instar larvae of Plutella xylostella xylostella with the same individual size and physiological state were reared indoors for generations.

Test agents: fenoxycarb (purchased from Hubei Xinrunde Chemical Co., Ltd.), phoxim (Hubei Jiufenglong Chemical Co., Ltd.), malathion (Hubei Jiufenglong Chemical Co., Ltd.), quinthion ( Hubei Jiufenglong Chemical Co., Ltd.), profenofos (Hubei Jiufenglong Chemical Co., Ltd.).

Test method: adopt poisonous leaf method, refer to "People's Republic of China Agricultural Industry Standard NY/T1154.2-2006", the specific method is as follows.

First, use a puncher with a diameter of 1 cm to punch out the leaf butterfly, put it into a petri dish, and keep it moist. Then use a capillary dropper to start with a low concentration of each treatment agent, drip 1 μL of the drug solution on each leaf butterfly, and after the solvent evaporates, combine it with another leaf butterfly coated with starch paste to form a poisonous leaf butterfly. wells in the wells of the tissue culture plate. Finally, one test insect was connected to each well of the tissue culture plate, and placed in an intelligent insect culture room with a temperature of 26±1°C and a relative humidity of 70%. After 2 to 4 hours of inoculation, after the test insects have eaten the leaf butterfly containing the medicine, add clean feed into the wells of the culture plate and continue to raise until the investigation, and eliminate the test insects that have not eaten a whole leaf butterfly. Four repetitions were set up for each treatment, and each repetition was not less than 12 venomous leaf butterflies, and the corresponding organic solvent treatment without the drug was set as the control. 24 hours after treatment, the death of test insects was investigated, and the total number of insects and the number of dead insects were recorded.

Statistical analysis was carried out with SPSS statistical analysis software, and the LC ₅₀ of each agent was calculated, and the co-toxicity coefficient (CTC value) of the mixture was calculated according to Sun Yunpei's method. The test results are shown in Table 1.

Actual toxicity index (ATI) = (standard drug LC ₅₀ /test drug LC ₅₀ )×100.

Theoretical toxicity index (TTI) = toxicity index of agent A × percentage content of A in the mixture + toxicity index of agent B × percentage content of B in the mixture.

Co-toxicity coefficient (CTC) = [measured toxicity index (ATI) of mixture/theoretical toxicity index (TTI) of mixture]×100.

According to the classification standard of NY/T11547.7-2006 combined action of insecticides: co-toxicity coefficient (CTC) ≥ 120 means synergistic effect; co-toxicity coefficient (CTC) ≤ 80 means antagonism; 80 < co-toxicity coefficient (CTC) )<120 shows an additive effect.

Table 1. Indoor combined toxicity assay

It can be seen from the above Table 1 that when the weight ratio of fenoxycarb and phoxim is 7-18:1, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥ 120. When the weight ratio of fenoxycarb and malathion is 1-9:1, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥120. When the weight ratio of fenoxycarb and quetiaphos is 1:6-24, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥120. When the weight ratio of fenoxycarb and profenofos is 1:14-31, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥120. When the weight ratio of fenoxycarb, phoxim and malathion is 11-19:3-12:1, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥120. When the weight ratio of fenoxycarb, quetiafos and profenofos is 3-13:1:26-39, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥120.

Formulation Example 1

This preparation example provides the microemulsion preparation of the binary compound agricultural composition of fenoxycarb and phoxim.

The microemulsion is composed of the following components by weight percentage: 20% of active ingredient, 8% of solvent, 2% of co-solvent, 10% of emulsifier, 1% of penetrant, and 100% of water supplement.

The active ingredients are fenoxycarb and phoxim, and the ratio of fenoxycarb to phoxim is 13:1 in terms of mass ratio.

The solvent is cyclohexanone, the cosolvent is N-methylpyrrolidone, the emulsifier is styrylphenol polyoxyethylene ether, and the penetrating agent is sodium alkylbenzenesulfonate.

Put the fenoxycarb and phoxim in the above weight ratio into the solvent and co-solvent and dissolve them all, then add a certain proportion of emulsifier and penetrant to the preparation kettle to make the oil phase, and slowly stir at 2000 rpm Inject deionized water to make up to 100%, and after passing the inspection, a transparent microemulsion is prepared.

Formulation Example 2

This preparation example provides the microemulsion preparation of the binary compound agricultural composition of fenoxycarb and malathion.

The microemulsion is composed of the following components by weight percentage: active ingredient 30%, solvent 10%, co-solvent 3%, emulsifier 12%, penetrant 3%, water supplement 100%.

The active ingredients are fenoxycarb and malathion, and the proportion of fenoxycarb and malathion is 1:1 in terms of mass ratio.

The solvent is cyclohexanone, the cosolvent is N-methylpyrrolidone, the emulsifier is styrylphenol polyoxyethylene ether, and the penetrating agent is sodium alkylbenzenesulfonate.

Put the fenoxycarb and malathion in the above weight ratio into the solvent and co-solvent and dissolve them all, add a certain proportion of emulsifier and penetrant to the preparation kettle to make the oil phase, and stir at 3000 rpm Slowly inject deionized water to make up to 100%, and after passing the inspection, a transparent microemulsion is prepared.

Formulation Example 3

This preparation example provides the microemulsion preparation of the binary compound agricultural composition of fenoxycarb and quinthiofos.

The microemulsion is composed of the following components by weight percentage: active ingredient 40%, solvent 15%, cosolvent 5%, emulsifier 20%, penetrant 5%, and water supplement 100%.

The active ingredients are fenoxycarb and quinalphos, and the ratio of fenoxycarb and quinalphos is 1:15 in terms of mass ratio.

The solvent is cyclohexanone, the cosolvent is N-methylpyrrolidone, the emulsifier is styrylphenol polyoxyethylene ether, and the penetrating agent is sodium alkylbenzenesulfonate.

Put the fenoxycarb and quetiafos in the above weight ratio into the solvent and co-solvent and dissolve them all, then add a certain proportion of emulsifier and penetrant to the preparation kettle to make the oil phase, and slowly stir at 6000 rpm Inject deionized water to make up to 100%, and after passing the inspection, a transparent microemulsion is prepared.

Formulation Example 4

This preparation example provides the microemulsion preparation of the agricultural composition compounded by fenoxycarb and profenofos binary.

The microemulsion is composed of the following components by weight percentage: 20% of active ingredient, 8% of solvent, 2% of co-solvent, 10% of emulsifier, 1% of penetrant, and 100% of water supplement.

The active ingredients are fenoxycarb and phoxim, and the ratio of fenoxycarb to profenofos is 1:22 in terms of mass ratio.

The solvent is cyclohexanone, the cosolvent is N-methylpyrrolidone, the emulsifier is styrylphenol polyoxyethylene ether, and the penetrating agent is sodium alkylbenzenesulfonate.

Put the fenoxycarb and profenofos in the above weight ratio into the solvent and co-solvent and dissolve them all, then add a certain proportion of emulsifier and penetrant to the preparation kettle to make the oil phase, slowly stir at 2000 rpm Inject deionized water to make up to 100%, and after passing the inspection, a transparent microemulsion is prepared.

Formulation Example 5

This preparation example provides the microemulsion preparation of the ternary compound agricultural composition of fenoxycarb, phoxim and malathion.

The microemulsion is composed of the following components by weight percentage: 20% of active ingredient, 8% of solvent, 2% of co-solvent, 10% of emulsifier, 1% of penetrant, and 100% of water supplement.

The active ingredients are fenoxycarb, phoxim and malathion, and the ratio of fenoxycarb, phoxim and malathion is 15:7:1 in terms of mass ratio.

The solvent is cyclohexanone, the cosolvent is N-methylpyrrolidone, the emulsifier is styrylphenol polyoxyethylene ether, and the penetrating agent is sodium alkylbenzenesulfonate.

Put the fenoxycarb, phoxim and malathion in the above weight ratio into the solvent and co-solvent and dissolve them all, then add a certain proportion of emulsifier and penetrant in the preparation kettle to make the oil phase Slowly inject deionized water to make up to 100% under stirring per minute, and after passing the inspection, a transparent microemulsion is prepared.

Formulation Example 6

This preparation example provides the microemulsion preparation of the ternary compound agricultural composition of fenoxycarb, quetiafos and profenofos.

The microemulsion is composed of the following components by weight percentage: 20% of active ingredient, 8% of solvent, 2% of co-solvent, 10% of emulsifier, 1% of penetrant, and 100% of water supplement.

The active ingredients are fenoxycarb, quinafos and profenofos, and the ratio of fenoxycarb, quinafos and profenofos is 7:1:30 in terms of mass ratio.

The solvent is cyclohexanone, the cosolvent is N-methylpyrrolidone, the emulsifier is styrylphenol polyoxyethylene ether, and the penetrating agent is sodium alkylbenzenesulfonate.

Put the fenoxycarb, quetiafos and profenofos in the above weight ratio into the solvent and the co-solvent and dissolve them all, then add a certain proportion of emulsifier and penetrant in the preparation kettle to make the oil phase, at 2000 rpm Slowly inject deionized water under stirring for 1 minute to make up to 100%, and after passing the inspection, a transparent microemulsion is prepared.

Example 2

This example provides an agricultural composition containing fenoxycarb and organophosphorus pesticides for the control test of cabbage beet armyworm.

The test site is Hanzhong City, Shaanxi Province. The cabbage variety is Zhonggan 11. In addition to beet armyworm, diamondback moth and Spodoptera litura occur in the field. The test groupings are shown in Table 2. The preparation method is referred to the preparation examples to make microemulsions. Each treatment is repeated 3 times, and the area of each treatment plot is 100m ² . Each test plot is arranged in random blocks. The single-dose treatments of fenoxycarb, phoxim, malathion, quinathion, and profenofos are all commercially available emulsifiable concentrate formulations. The pesticide was applied at the rosette stage of cabbage, and the control area was sprayed with clear water without spraying the pesticide, and the rest of the test fields were the pesticide-treated zone, sprayed with different microemulsions. For each 667m ² , add 500kg of water according to the prescribed dosage, and the dosage of active ingredients is uniformly 5g/hm ² . Use Gongnong-16 manual sprayer to spray evenly by hand. Investigate the insect population base before spraying, investigate the number of living insects on the 2nd and 7th days after spraying, calculate the control effect, and observe the safety of the test agent on the crops, and calculate the control effect of each repetition according to the following formula.

Control effect = [1-(the number of insects in the blank control group before spraying × the number of insects in the treatment group after spraying) / (the number of insects in the blank control group after spraying × the number of insects in the treatment group before spraying)] × 100%

Table 2: Control effect of cabbage beet armyworm

From the test results in Table 2, it can be seen that the combination of fenoxycarb and organophosphorus pesticides can effectively control cabbage beet armyworm, and the control effect on cabbage beet armyworm 2 days and 7 days after application is significantly better than that of 5 pesticides. The control medicament showed a synergistic effect, and it was found that the attenuation rate of the anti-efficacy after compounding was lower than that of the control medicament. The direct impact on crops was observed irregularly during the test period, and the test and control chemicals did not produce abnormal phenomena on the growth of cabbage. Effects on other pests and diseases Through the observation of the blank area and the pesticide treatment area, the test pesticide has a good control effect on diamondback moth and Spodoptera litura, which occur simultaneously with beet armyworm, and is safe and harmless to crops. The impact on other non-target organisms was observed irregularly during the test, and no impact on other non-target organisms was found.

As mentioned above, the present invention can be better realized. The above-mentioned embodiment is only a description of the preferred implementation of the present invention, and does not limit the scope of the present invention. Various changes and improvements made by technicians to the technical solutions of the present invention shall fall within the scope of protection determined by the present invention.

Claims (10)

1. An agricultural composition containing fenoxycarb and organophosphorus pesticides, characterized in that, the active ingredient comprises component A and component B, and said component A is fenoxycarb, and said component B is organophosphorus Pesticide; the organophosphorus pesticide is selected from phoxim, malathion, quinathion and profenofos. 2. The agricultural composition according to claim 1, wherein the active ingredient comprises fenoxycarb and phoxim; In terms of mass ratio, the ratio of fenoxycarb to phoxim is 7-18:1. 3. The agricultural composition according to claim 1, wherein the active ingredient comprises fenoxycarb and malathion; In terms of mass ratio, the ratio of fenoxycarb to malathion is 1-9:1. 4. The agricultural composition according to claim 1, wherein the active ingredient comprises fenoxycarb and quetiaphos; In terms of mass ratio, the ratio of fenoxycarb to quetiafos is 1:6-24. 5. The agricultural composition according to claim 1, wherein the active ingredient comprises fenoxycarb and profenofos; In terms of mass ratio, the ratio of fenoxycarb to profenofos is 1:14-31. 6. The agricultural composition according to claim 1, wherein the active ingredient comprises fenoxycarb, phoxim and malathion; In terms of mass ratio, the ratio of fenoxycarb, phoxim and malathion is 11-19:3-12:1. 7. The agricultural composition according to claim 1, wherein the active ingredient comprises fenoxycarb, quetiafos and profenofos; In terms of mass ratio, the ratio of fenoxycarb, quetiafos and profenofos is 3-13:1:26-39. 8. The application of the agricultural composition according to any one of claims 1 to 7 in preventing and controlling food crops and vegetable pests. 9. The application according to claim 8, characterized in that the pests are Lepidoptera pests. 10. The application according to claim 9, wherein the pests are cotton bollworm, diamondback moth, cabbage caterpillar, and noctuid.