CN116584494A - Agricultural composition containing fenoxycarb and chlorantraniliprole - Google Patents

Abstract

The invention belongs to the technical field of pesticide compounding, and relates to an agricultural composition containing fenoxycarb and chlorantraniliprole. The invention provides an agricultural composition containing fenoxycarb and chlorantraniliprole, the active ingredients of which include fenoxycarb and chlorantraniliprole. The ratio is 20～12:1. The present invention finds through indoor toxicity testing that fenoxycarb and chlorantraniliprole have excellent insecticidal effects within a certain proportion range, showing a synergistic effect.

Description

An agricultural composition containing fenoxycarb and chlorantraniliprole

technical field

The invention belongs to the technical field of pesticide compounding, and relates to an agricultural composition containing fenoxycarb and chlorantraniliprole.

Background technique

Fenoxycarb, its chemical name is 2-(p-phenoxyphenoxy) ethyl carbamate, it is a non-terpene carbamate compound, has stomach toxicity and contact action, and has As an insect growth regulator, it has a broad-spectrum insecticidal effect; however, its insecticidal effect is non-neurological, and it has a strong juvenile hormone activity on a variety of insects, which can lead to egg killing, inhibit the metamorphosis of adult stages and the growth of larvae. Moulting, resulting in the death of larvae or pupal stage, specific insecticide, harmless to bees and beneficial organisms. Fenoxycarb is mainly used in warehouses to prevent and control storage pests. Wells have the function of regulating insect growth, such as destroying the unique metamorphosis of insects, spraying barns to prevent the reproduction of Coleoptera and Lepidoptera pests, spraying indoor cracks to prevent cockroaches, fleas etc. It can be made into bait to control various ant colonies such as fire ants and termites. It can be used to prevent mosquito larvae from developing into adults in cotton fields, orchards, vegetable gardens and ornamental plants. It can effectively prevent and control psyllids, scales, leaf rollers, etc. It is also effective against pests that are resistant to the current commonly used pesticides.

Chlorantraniliprole is a brand-new o-amidobenzamide insecticide, which has excellent control effects on various agricultural pests such as Lepidoptera, Coleoptera, Hemiptera, Diptera, etc., especially In rice production, it has a good control effect on Lepidoptera pests and has a high safety factor. It has high safety against non-target arthropods (such as rice field spiders), and has extremely low toxicity to mammals, fish and birds. In recent years, the drug has been widely used in the comprehensive management of rice pests. However, long-term chemical pesticide input also brings many negative effects, such as environmental pollution, pest resistance, pesticide residues on harvested crops, and damage to non-target organisms.

Essential oil is also called aromatic oil or volatile oil. Plant essential oil is a kind of volatile secondary metabolites in plants. It is composed of simple compounds with relatively small molecular weight, which can be distilled with water vapor and is a general term for oily liquid substances that can be volatilized at room temperature. Salt Artemisia (Artemisia halodendron) is a common semi-shrub on grassland and shifting sand, distributed in northeast, northwest and Inner Mongolia (Beijing Institute of Botany, Chinese Academy of Sciences, 1975). In traditional Chinese medicine, it is used for relieving cough, eliminating phlegm, relieving asthma, relieving exterior syndrome, and removing dampness. Indications for chronic bronchitis, asthma, etc. ("National Chinese Herbal Medicine Compilation" compilation group, 1975). So far, there is no report about the compounding of Artemisia salina and other insecticides.

Insecticide varieties containing a single active ingredient often have different degrees of defects in the control of agricultural pests, such as: narrow insecticidal spectrum, pests are prone to resistance after continuous use, and frequent use will aggravate environmental pollution. The combination of active ingredients with different mechanisms of action can effectively overcome the above shortcomings. At the same time, the synergistic effect produced by mixing the two active components can improve the control effect, expand the insecticidal spectrum, delay the generation of pest resistance, and reduce environmental pollution. It is an important means of comprehensive pest control. However, in most cases, the compound effects of pesticides are additive, and there are fewer compounds showing synergistic effects, especially those with very obvious synergistic effects and high co-toxicity coefficients. At present, there is no report on the combination of the two active ingredients fenoxycarb and chlorantraniliprole, or the combination of the three active ingredients fenoxycarb, chlorantraniliprole, and Artemisia salina essential oil.

Contents of the invention

The object of the present invention is to provide an agricultural composition containing fenoxycarb and chlorantraniliprole, the active ingredients of which are fenoxycarb and chlorantraniliprole compounded according to a specific ratio. The mechanism of action is different. It has been verified that their combination produces a good synergistic effect, expands the insecticidal spectrum, slows down the generation of drug resistance, improves the insecticidal effect, and is conducive to the sustainable development of the environment. The object of the present invention is to provide an agricultural composition compounded by fenoxycarb, chlorantraniliprole and Artemisia salina essential oil. It has been verified that their compounding produces a good synergistic effect.

Based on the above purpose, the present invention provides an agricultural composition containing fenoxycarb and chlorantraniliprole, the active ingredients of which include fenoxycarb and chlorantraniliprole; in terms of mass ratio, fenoxycarb and chlorantraniliprole The ratio of benzamide is 20-12:1.

Those of ordinary skill in the art are easy to know that to improve the efficacy of agricultural compositions and avoid the occurrence of drug resistance, multiple pesticides are used in combination or in combination. However, due to the unknown components and internal mechanisms, multiple pesticides are used in combination. Or whether the control effect after combined use is synergistic is difficult to predict. After in-depth experimental research, the inventors have conducted in-depth experiments, and according to the comprehensive effect evaluation shown in field experiments, the insecticidal composition of the present invention has excellent control effects on Lepidoptera pests, and is better than the use effect of a single agent. .

Preferably, in the agricultural composition provided by the present invention, the ratio of fenoxycarb to chlorantraniliprole is 17-14:1 in terms of mass ratio.

More preferably, in the agricultural composition provided by the present invention, in terms of mass ratio, the ratio of fenoxycarb to chlorantraniliprole is 15.5:1.

Further, in the agricultural composition provided by the present invention, Artemisia salina essential oil is also included.

Further, in the agricultural composition provided by the present invention, the ratio of fenoxycarb, chlorantraniliprole and Artemisia salina essential oil is 20-12:1:5-10 in terms of mass ratio.

Specifically, the preparation method of Artemisia halodendron essential oil provided by the present invention is obtained by steam distillation after the whole plant of Artemisia halodendron is dried and pulverized.

According to actual application requirements, the composition of the present invention can be prepared into one of dosage forms such as aqueous emulsion, microemulsion, suspension concentrate, wettable powder, and water-dispersible granule according to methods known to those skilled in the art. The functional composition also contains auxiliary agents required for the preparation of pesticide formulations, auxiliary agents can be solvents, emulsifiers, wetting agents, stabilizers, dispersants, thickeners, pH regulators, defoamers, antifreeze One or a combination of agents, fillers, etc. The adjuvants described in the present invention can be all known substances, such as various adjuvants commonly used in pesticide preparations, which can vary according to different situations.

The method of application can be spraying, root irrigation, root soaking, seed soaking, watering, throwing, spreading, furrow application, hole application, etc. Spray treatment is preferred when controlling pests, and the preferred formulation for controlling pests is water emulsion.

The present invention also provides a method for preparing fenoxycarb, chlorantraniliprole and Artemisia salina essential oil into an emulsion in water, the suspending agent is composed of the following components by weight percentage: active ingredient 20-40%, edible vegetable oil 10-15% , silicone oil 3-5%, alkylphenol polyoxyethylene ether formaldehyde condensate 7-10%, cyanoethyl cellulose 3-5%, glycerin 3-6%, water supplement 100%.

Mix the fenoxycarb, chlorantraniliprole, and Artemisia salina essential oil in the above weight ratio with edible vegetable oil, silicone oil, and cyanoethyl cellulose under mechanical stirring, and add the alkylphenol polyoxyethylene ether formaldehyde condensate to stir and mix uniform, then add glycerol and water, and stir for 30 minutes at a speed of 8,000 rpm to prepare a water emulsion.

The composition of the present invention is mainly used for controlling pests in food crops and vegetables, and the pests are preferably Lepidoptera pests, such as cotton bollworm, diamondback moth, stem borer or noctuid.

Compared with the prior art, the technical solution provided by the present invention has the following beneficial effects or advantages:

Compared with the prior art, the main contribution of the present invention is to provide an agricultural composition containing fenoxycarb and chlorantraniliprole, which has an excellent control effect on plant pests. The inventor of this patent conducted a field drug efficacy test on the composition and found that within the given ratio range of the present invention, the composition has a better control effect on plant pests than a single dose, indicating that the combination has a synergistic effect . Another contribution of the present invention lies in the compounding of fenoxycarb, chlorantraniliprole and Artemisia salina essential oil. The effect of the composition on controlling plant pests is better than that of a single dose, indicating that the combination has a synergistic effect.

Detailed ways

In the following, the technical solution of the present invention will be described in conjunction with examples, but the present invention is not limited to the following examples.

Example 1

This example provides an indoor combined toxicity test of an agricultural composition containing fenoxycarb and chlorantraniliprole against diamondback moth.

Test worms: third-instar larvae of Plutella xylostella xylostella with the same individual size and physiological state were reared indoors for generations.

Test agents: fenoxycarb (purchased from Hubei Xinrunde Chemical Co., Ltd.), chlorantraniliprole (purchased from Chongqing Huage Biochemical Co., Ltd.), Artemisia halodendron essential oil (dried whole plant of Artemisia halodendron) After crushing, obtained by steam distillation).

Test method: adopt poisonous leaf method, refer to "People's Republic of China Agricultural Industry Standard NY/T1154.2-2006", the specific method is as follows.

First, use a puncher with a diameter of 1 cm to punch out the leaf butterfly, put it into a petri dish, and keep it moist. Then use a capillary dropper to start with a low concentration of each treatment agent, drip 1 μL of the drug solution on each leaf butterfly, and after the solvent evaporates, combine it with another leaf butterfly coated with starch paste to form a poisonous leaf butterfly. wells in the wells of the tissue culture plate. Finally, one test insect was connected to each well of the tissue culture plate, and placed in an intelligent insect culture room with a temperature of 26±1°C and a relative humidity of 70%. After 2 to 4 hours of inoculation, after the test insects have eaten the leaf butterfly containing the medicine, add clean feed into the wells of the culture plate and continue to raise until the investigation, and eliminate the test insects that have not eaten a whole leaf butterfly. Four repetitions were set up for each treatment, and each repetition was not less than 12 venomous leaf butterflies, and the corresponding organic solvent treatment without the drug was set as the control. 24 hours after treatment, the death of test insects was investigated, and the total number of insects and the number of dead insects were recorded.

Statistical analysis was carried out with SPSS statistical analysis software, and the LC ₅₀ of each agent was calculated, and the co-toxicity coefficient (CTC value) of the mixture was calculated according to Sun Yunpei's method. The test results are shown in Table 1.

Actual toxicity index (ATI) = (standard drug LC ₅₀ /test drug LC ₅₀ )×100.

Theoretical toxicity index (TTI) = toxicity index of agent A × percentage content of A in the mixture + toxicity index of agent B × percentage content of B in the mixture.

Co-toxicity coefficient (CTC) = [measured toxicity index (ATI) of mixture/theoretical toxicity index (TTI) of mixture]×100.

According to the classification standard of NY/T11547.7-2006 combined action of insecticides: co-toxicity coefficient (CTC) ≥ 120 means synergistic effect; co-toxicity coefficient (CTC) ≤ 80 means antagonism; 80 < co-toxicity coefficient (CTC) )<120 shows an additive effect.

Table 1. Indoor combined toxicity assay

It can be seen from the above table 1 that when the weight ratio of fenoxycarb and chlorantraniliprole is 20:1 and 5:1, it shows an additive effect, and the weight ratio of fenoxycarb and chlorantraniliprole is between 20 and 5:1. When the ratio is 12:1, it shows a synergistic effect, and the co-toxicity coefficient (CTC) is ≥120. When the mass ratio of fenoxycarb and chlorantraniliprole was 15.5:1, the co-toxicity coefficient reached 161.17. When the weight ratio of fenoxycarb, chlorantraniliprole and Artemisia salina essential oil is 20-12:1:5-10, it also exhibits synergistic effect, and the co-toxicity coefficient (CTC) is ≥120.

Formulation Example 1

This preparation example provides an aqueous emulsion preparation of an agricultural composition containing fenoxycarb and chlorantraniliprole.

The emulsion in water is composed of the following components by weight percentage: active ingredient (in terms of mass ratio, phenoxycarb: chlorantraniliprole=20:1) 20%, sunflower oil 10%, silicone oil 3%, alkylphenol Polyoxyethylene ether formaldehyde condensate 7%, cyanoethyl cellulose 3%, glycerin 3%, water make up 100%.

Mix fenoxycarb, chlorantraniliprole, edible vegetable oil, silicone oil, and cyanoethyl cellulose in the above weight ratio evenly under mechanical stirring, add alkylphenol polyoxyethylene ether formaldehyde condensate, stir and mix evenly, and then add Glycerol and water were stirred at a speed of 8000 rpm for 30 minutes to obtain a water emulsion.

Formulation Example 2

This preparation example provides an aqueous emulsion preparation of an agricultural composition containing fenoxycarb and chlorantraniliprole.

The emulsion in water is composed of the following components by weight percentage: active ingredient (in terms of mass ratio, fenoxycarb: chlorantraniliprole: Artemisia salina essential oil=20:1:5) 40%, sunflower oil 15%, silicone oil 5%, alkylphenol polyoxyethylene ether formaldehyde condensate 10%, cyanoethyl cellulose 5%, glycerin 6%, water to make up 100%.

Mix the fenoxycarb, chlorantraniliprole, artemisia essential oil, edible vegetable oil, silicone oil, and cyanoethyl cellulose in the above weight ratio evenly under mechanical stirring, and add the alkylphenol polyoxyethylene ether formaldehyde condensate to stir and mix uniform, then add glycerol and water, and stir for 30 minutes at a speed of 8,000 rpm to prepare a water emulsion.

Example 2

This example provides an agricultural composition containing fenoxycarb and chlorantraniliprole for the control test of rice stem borer.

The test location is Jinhua City, Zhejiang Province, and the rice variety is Zhejingyou 77. The test groups are shown in Table 2. Each treatment is repeated 3 times, and the area of each treatment plot is 666.7m ² . Each test plot is arranged in random blocks. When the pesticide was applied, it was at the early stage of the occurrence of rice stem borer. A paddy field was selected as a blank control area. The control area was sprayed with water and no pesticide was applied. The rest of the test fields were treated with pesticides. Different water emulsions were sprayed. The preparation method refers to the preparation Example. For each 667m ² , add 450kg of water according to the prescribed dosage, and the dosage of active ingredients is uniformly 5g/hm ² . Use Gongnong-16 manual sprayer to spray evenly by hand.

Investigate the insect population base before spraying, investigate the number of live insects on the 3rd, 7th, and 14th days after spraying, calculate the control effect, and observe the safety of the test agent on the crops, and calculate the control effect of each repetition according to the following formula.

Control effect = [1-(the number of insects in the blank control group before spraying × the number of insects in the treatment group after spraying) / (the number of insects in the blank control group after spraying × the number of insects in the treatment group before spraying)] × 100%

Table 2: Control effect of rice stem borer

From the test results in Table 2, it can be seen that the combination of fenoxycarb and chlorantraniliprole can effectively control rice stem borer, and the combination of fenoxycarb, chlorantraniliprole and Artemisia salina essential oil can effectively control rice stem borer. Chilo borer, 3 days, 7 days, and 14 days after application, the control effect on rice stem borer was significantly better than that of the three control pesticides, showing a synergistic effect. According to the observation of the whole process of the field test, within the range of the test dosage, the rice grows well, and there is no phytotoxicity phenomenon in each treatment, which shows that it is safe to the rice.

As mentioned above, the present invention can be better realized. The above-mentioned embodiment is only a description of the preferred implementation of the present invention, and does not limit the scope of the present invention. Various changes and improvements made by technicians to the technical solutions of the present invention shall fall within the scope of protection determined by the present invention.

Claims (8)

1. An agricultural composition containing fenoxycarb and chlorantraniliprole is characterized in that the active ingredients comprise fenoxycarb and chlorantraniliprole;

the mass ratio of the fenoxycarb to the chlorantraniliprole is 20-12:1.

2. The agricultural composition of claim 1, wherein the ratio of fenoxycarb to chlorantraniliprole is 17-14:1 in terms of mass ratio.

3. The agricultural composition of claim 1, wherein the ratio of fenoxycarb to chlorantraniliprole is 15.5:1 in terms of mass ratio.

4. The agricultural composition of claim 1 further comprising an essential oil of artemisia halodendron.

5. The agricultural composition of claim 4, wherein the ratio of fenoxycarb, chlorantraniliprole and artemisia halodendron essential oil is 20-12:1:5-10 in terms of mass ratio.

6. Use of the agricultural composition according to any one of claims 1 to 5 for controlling insect pests of food crops and vegetables.

7. The use according to claim 6, wherein the pest is a lepidopteran pest.

8. The use according to claim 6, wherein the pest is cotton bollworm, plutella xylostella, borer or noctuid.