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CN116212162B - Microinjection auxiliary device - Google Patents

Microinjection auxiliary device Download PDF

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Publication number
CN116212162B
CN116212162B CN202211723328.7A CN202211723328A CN116212162B CN 116212162 B CN116212162 B CN 116212162B CN 202211723328 A CN202211723328 A CN 202211723328A CN 116212162 B CN116212162 B CN 116212162B
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CN
China
Prior art keywords
gear
rod
shell
liquid suction
push rod
Prior art date
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Active
Application number
CN202211723328.7A
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Chinese (zh)
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CN116212162A (en
Inventor
邹远康
翟茂登
骆文静
郑刚
张建彬
赵芳
周杨
孙亚菲
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Fourth Military Medical University FMMU
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Fourth Military Medical University FMMU
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Priority to CN202211723328.7A priority Critical patent/CN116212162B/en
Publication of CN116212162A publication Critical patent/CN116212162A/en
Application granted granted Critical
Publication of CN116212162B publication Critical patent/CN116212162B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3134Syringe barrels characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M5/3135Syringe barrels characterised by constructional features of the proximal end
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31515Connection of piston with piston rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • A61M5/31526Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • A61M5/3153Dosing by single stroke limiting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31556Accuracy improving means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566Means improving security or handling thereof
    • A61M5/31573Accuracy improving means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M2005/3114Filling or refilling

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention relates to the technical field of microinjection mechanisms, and particularly discloses a microinjection auxiliary device, which comprises a shell, wherein one end of the shell is provided with a fixing piece for connecting a capillary tube; the shell is internally provided with a liquid suction mechanism and a connecting mechanism, the liquid suction mechanism comprises a liquid suction gear, a piston push rod and a connecting rod, the liquid suction gear is positioned between the piston push rod and the connecting rod and meshed with the piston push rod and the connecting rod through a rack, the connecting rod moves along the direction away from the capillary, and the piston push rod is inserted into the capillary; the liquid suction gear is coaxially provided with a ratchet wheel, a hollow injection gear is sleeved outside the ratchet wheel, and a pawl is arranged on the inner wall of the injection gear; the injection mechanism comprises a connecting gear meshed with the injection gear and a pressing rod meshed with the connecting gear through a rack; pressing down the pressing rod, and enabling the liquid suction gear to rotate along with the ratchet wheel; the push rod is lifted up, and the ratchet wheel is kept static. The invention solves the problems that the sucking and injecting quantity and the injecting pressure are difficult to control, the sucking and injecting quantity can not be adjusted, the injecting operation is complex and the like when the microinjection needle is used.

Description

Microinjection auxiliary device
Technical Field
The invention belongs to the technical field of medical instruments, relates to the technical field of microinjection, and particularly relates to a microinjection auxiliary device.
Background
The microinjection needle is a disposable injection needle formed by drawing after heating a capillary glass tube, the needle point material is fragile and easy to break, the injection quantity is tiny, and the injection support device is unstable during injection, so that the problems of difficulty in accurately controlling the suction quantity and the injection quantity are solved. The microinjection needle is usually prepared before use, and after one use, another injection needle should be replaced, so that the device is convenient to replace and the tightness of the device is ensured.
At present, most of injection use conditions of microinjection needles are pneumatic, the injection is carried out by utilizing gas pressure, the problems that the pressure is difficult to control, the operation is complex during injection and the like exist, the inner diameters can be ensured to be uniform when a capillary glass tube is drawn, but the lengths are different, the graduations are difficult to accurately mark, and the quantity of each suction and injection is difficult to control.
Disclosure of Invention
In order to solve the problems that the pressure is difficult to control, the scale is not accurately calibrated, the sucking and injecting quantity is difficult to control, the operation is complex during injection and the like when the microinjection needle is used, the invention provides a microinjection auxiliary device which is realized by adopting the following technical scheme:
The microinjection auxiliary device comprises a cuboid shell, wherein a liquid suction mechanism and an injection mechanism are arranged in the shell, a fixing piece is arranged at one end of the shell in the length direction, and the shell is detachably connected with one end of a capillary tube through the fixing piece;
The liquid suction mechanism comprises a linkage gear, a piston push rod and a connecting rod which are arranged in parallel, and the piston push rod and the connecting rod are both in sliding connection with the inner wall of the shell; the piston push rod and the capillary tube are coaxially arranged, and a first rack is arranged at one end, far away from the capillary tube, of the piston push rod in the length direction; a second rack is arranged at one end, close to the capillary tube, of the connecting rod in the length direction;
the linkage gear comprises a liquid suction gear which is rotationally connected with the inner wall of the shell, the liquid suction gear is positioned between the piston push rod and the connecting rod, and the liquid suction gear is meshed with the piston push rod through a first rack and is meshed with the connecting rod through a second rack; the connecting rod is moved in a direction away from the capillary tube, the liquid suction gear drives the piston push rod to be far away from one end of the liquid suction gear is inserted into the capillary tube;
The linkage gear also comprises a hollow injection gear coaxially arranged with the liquid suction gear, one end of the liquid suction gear is coaxially and fixedly connected with a ratchet wheel, the injection gear is sleeved outside the ratchet wheel, at least one pawl is arranged on the inner wall of the injection gear, and the pawl and the ratchet wheel form a ratchet mechanism; the pawl is rotationally connected with the inner wall of the injection gear through a torsion spring; the injection gear and the ratchet wheel are both rotationally connected with the inner wall of the shell;
The injection mechanism comprises a pressing rod and a connecting gear, the pressing rod is in sliding connection with the shell, the connecting gear is meshed with the injection gear, a third rack is arranged in the length direction of the pressing rod and is meshed with the connecting gear, and one end, far away from the connecting gear, of the pressing rod penetrates through the shell to extend out; when the pressing rod moves along the direction close to the connecting gear, the pawl is abutted with the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel to drive the ratchet wheel to rotate, and at the moment, the liquid suction gear rotates along with the ratchet wheel to drive the piston push rod to move towards the direction far away from the liquid suction gear; when the pressing rod moves along the direction away from the connecting gear, the pawl slides over the back of the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel, and the ratchet wheel is kept stationary.
Further, one end, far away from the capillary, of the connecting rod is coaxially connected with a push rod, and one end, far away from the connecting rod, of the push rod penetrates through the shell to extend out and is in sliding connection with the shell.
Further, one end of the pressing rod, which is far away from the connecting gear, is connected with a pressing button through a damping spring.
Further, one end of the pressing rod, which is far away from the pressing button, is connected with a transmission piece through a return spring, and the pressing rod is coaxially and fixedly connected with the return spring;
The transmission part comprises a connecting plate arranged along the length direction of the pressing rod, and the connecting plate is in sliding connection with the inner wall of the shell; a blocking plate is vertically fixed at one end, far away from the pressing button, of the connecting plate, a guide rod is vertically fixed on the blocking plate, and the guide rod axially penetrates through the reset spring to be in sliding connection with the pressing rod;
The connecting plate is provided with a fourth rack along the length direction of the pressing rod, the injection mechanism further comprises an adjusting gear meshed with the fourth rack, the adjusting gear is rotationally connected with the shell, and one end of the adjusting gear penetrates through the shell and is coaxially fixed with a knob.
By adopting the technical scheme, the push rod is pulled towards the direction far away from the shell, so that the connecting rod can be driven to move towards the direction far away from the liquid suction gear, the liquid suction gear can be driven to rotate, and then the piston push rod is driven to move along the direction far away from the liquid suction gear, so that one end of the piston push rod is inserted into the capillary tube; pushing the push rod towards the direction close to the shell, so that the piston push rod can be pulled out of the capillary tube; thus, the push rod can complete the process of sucking liquid by the capillary tube by controlling the movement of the piston push rod;
Before injection, the knob is rotated to drive the connecting plate to drive the pressing rod to move towards the direction away from the blocking plate, so that the injection quantity can be adjusted; when the injection is performed, the pressing button is pressed, the pressing rod can be driven to be pressed down, so that the connecting gear is driven to rotate, the liquid suction gear is driven to rotate, the piston push rod moves towards the direction away from the liquid suction gear, and the injection can be completed; after the injection is completed, the reset spring drives the push rod back to the position in front of the injector for the next operation. And the reset spring and the damping spring reduce the possibility of excessive force and improve the stability of injection.
Further, the device also comprises a liquid suction amount adjusting mechanism, wherein the liquid suction amount adjusting mechanism comprises a threaded rod coaxially arranged with the connecting rod, a movable groove for the threaded rod to be inserted is formed in the axis direction of the connecting rod, one end of the threaded rod is in sliding connection with the connecting rod, and the other end of the threaded rod is in rotary connection with the shell;
One end of the threaded rod far away from the connecting rod an adjusting button is fixedly connected through the shell; the threaded rod threaded connection has the stopper, the stopper is located between adjusting knob and the connecting rod, and the stopper keeps away from threaded rod one end protrusion in the casing, and the spacing groove that supplies the stopper to follow threaded rod axial motion has been seted up to the casing.
Through adopting above-mentioned technical scheme, pulling push rod for after piston push rod one end inserts the capillary completely in, rotate the adjusting knob, can adjust the distance between stopper and the connecting rod, thereby realize the regulation to the interior liquid absorption volume of capillary.
Further, the fixing piece comprises a fixing cap and an inverted cone-shaped silica gel sleeve for the capillary to axially pass through, and the inverted cone-shaped silica gel sleeve is wrapped on the outer wall of the capillary and is detachably connected with the capillary;
The casing length direction one end is provided with the connecting pipe that supplies back taper silica gel cover male, and the less one end of back taper silica gel cover diameter orientation casing, connecting pipe outer wall and fixed cap inner wall threaded connection, when connecting pipe and fixed cap are connected, the connecting pipe presss from both sides tight back taper silica gel cover.
Further, the shell is provided with a buckle for supporting fingers.
Through the technical scheme, when the capillary tube is installed, one end of the capillary tube passes through the reverse taper silica gel sleeve along the axial direction of the reverse taper silica gel sleeve, the reverse taper silica gel sleeve is inserted into the connecting tube, and then one end of the capillary tube far away from the reverse taper silica gel sleeve passes through the fixing cap along the axial direction of the fixing cap, so that the fixing cap is in threaded connection with the connecting tube, the reverse taper silica gel sleeve can be clamped, the detachable connection of the capillary tube and the shell is realized, and the stability of the capillary tube and the convenience for replacing the capillary tube are improved; the arrangement of the buckle can support the small finger of an operator during injection, so that the possibility of dropping the injection auxiliary device is reduced.
Compared with the prior art, the microinjection auxiliary device has the following technical effects:
1. through setting up casing, connecting rod, push rod, imbibition gear and piston push rod, the push rod is pulled towards keeping away from the casing direction, can drive the connecting rod towards keeping away from imbibition gear direction motion to drive imbibition gear rotation, in order to drive piston push rod along keeping away from imbibition gear direction motion, and then make piston push rod one end insert in the capillary; pushing the push rod towards the direction close to the shell, so that the piston push rod can be pulled out of the capillary tube; therefore, the push rod can complete the process of sucking liquid by the capillary tube by controlling the movement of the piston push rod.
2. The injection quantity can be adjusted by arranging a ratchet wheel, a pawl, an injection gear, a connecting gear, a pressing rod, a reset spring, a damping spring, a transmission piece and a knob and rotating the knob before injection to drive a connecting plate to drive the pressing rod to move towards a direction far away from a blocking plate; when the injection is performed, the pressing button is pressed, the pressing rod can be driven to be pressed down, so that the connecting gear is driven to rotate, the liquid suction gear is driven to rotate, the piston push rod moves towards the direction away from the liquid suction gear, and the injection can be completed; after the injection is completed, the reset spring drives the push rod back to the position in front of the injector for the next operation. And the reset spring and the damping spring reduce the possibility of excessive force and improve the stability of injection.
3. Through setting up threaded rod, stopper and adjusting knob, pulling push rod for after piston push rod one end inserts the capillary completely in, rotate the adjusting knob, can adjust the distance between stopper and the connecting rod, thereby realize the regulation to the interior liquid absorption volume of capillary.
4. Through setting up reverse taper silica gel cover, fixed cap, connecting pipe and buckle, when installing the capillary, pass back with capillary one end along reverse taper silica gel cover axis direction, insert the connecting pipe with reverse taper silica gel cover, afterwards pass the fixed cap with capillary one end far away from reverse taper silica gel cover along fixed cap axis direction for fixed cap and connecting pipe threaded connection can make reverse taper silica gel cover clamped, realizes the detachable connection of capillary and casing, has improved the stability of capillary and has changed the convenience of capillary; the arrangement of the buckle can support the small finger of an operator during injection, so that the possibility of dropping the injection auxiliary device is reduced.
Drawings
Fig. 1 is a schematic overall structure of an auxiliary microinjection apparatus according to an embodiment of the present invention.
Fig. 2 is a schematic structural view of a fixing member according to an embodiment of the present invention.
Fig. 3 is a schematic perspective view of a pipetting mechanism and an injection mechanism according to an embodiment of the invention.
Fig. 4 is a diagram showing the relationship between the liquid suction mechanism and the injection mechanism in the embodiment of the present invention.
Fig. 5 is a schematic structural diagram of a linkage gear according to an embodiment of the present invention.
Fig. 6 is a schematic structural view of an injection mechanism according to an embodiment of the present invention.
Fig. 7 is a schematic structural view of a liquid suction amount adjusting mechanism in an embodiment of the present invention.
Reference numerals illustrate: 1. a capillary tube; 2. a fixing cap; 3. an inverted cone-shaped silica gel sleeve; 4. a piston push rod; 5. a linkage gear; 6. a connecting rod; 7. a push rod; 8. an adjusting knob; 9. a limiting block; 10. a threaded rod; 11. an adjusting gear; 12. a knob; 13. a transmission member; 14. a return spring; 15. pressing the rod; 16. a damping spring; 17. pressing a button; 18. and (5) a buckle.
Detailed Description
The details of the present invention are explained in further detail below with reference to fig. 1-7.
The invention discloses a microinjection auxiliary device. Referring to fig. 1 and 2, the auxiliary device includes a housing, and the housing main body has a rectangular parallelepiped-like structure in appearance, one end of the housing in a length direction is provided with a fixing member for fixing the capillary tube 1, and one end of the capillary tube 1 is detachably connected with the housing through the fixing member; the housing is integrally formed with a clasp 18 for holding a finger. The fixing piece comprises a fixing cap 2 and an inverted cone-shaped silica gel sleeve 3 which is used for the capillary 1 to axially pass through, the inverted cone-shaped silica gel sleeve 3 is wrapped on the outer wall of the capillary 1 and is detachably connected with the capillary 1, and the smaller diameter end of the inverted cone-shaped silica gel sleeve 3 faces the shell; the casing is provided with the connecting pipe that supplies back taper silica gel cover 3 male, and connecting pipe outer wall and fixed cap 2 inner wall threaded connection, and when connecting pipe and fixed cap 2 were connected, back taper silica gel cover 3 was located the airtight space that forms between fixed cap 2 and the casing, and the connecting pipe presss from both sides tight back taper silica gel cover 3, has realized the pressurization of back taper silica gel cover 3 and has fixed.
When the capillary 1 is installed, one end of the capillary 1 passes through the reverse taper silica gel sleeve 3, the reverse taper silica gel sleeve 3 is inserted into the connecting pipe, and then one end of the capillary 1, which is far away from the reverse taper silica gel sleeve 3, axially passes through the fixing cap 2, so that the inner wall of the fixing cap 2 is in threaded connection with the outer wall of the connecting pipe, the reverse taper silica gel sleeve 3 can be clamped, the detachable connection of the capillary 1 and the shell is realized, and the stability of the capillary 1 and the convenience of replacing the capillary 1 are improved.
Referring to fig. 3, 4 and 5, a liquid suction mechanism is arranged in the shell, the liquid suction mechanism comprises a linkage gear 5, a push rod 7 and a piston push rod 4, the linkage gear 5 comprises a liquid suction gear, and two ends of the direction of a rotating shaft of the liquid suction gear are rotatably connected with the shell. The piston push rod 4 is coaxially arranged with the capillary tube 1, a first rack is arranged in the length direction of the piston push rod 4, and the liquid suction gear is meshed with the piston push rod 4 through the first rack and is used for driving one end, far away from the liquid suction gear, of the piston push rod 4 to be inserted into the capillary tube 1; one end of the push rod 7 is fixedly connected with a connecting rod 6, the connecting rod 6 and the push rod 7 are coaxially arranged and are parallel to the piston push rod 4, and a liquid suction gear is positioned between the piston push rod 4 and the connecting rod 6; a second rack is arranged on one surface of the connecting rod 6, which faces the piston push rod 4 in the length direction, and the liquid suction gear is meshed with the connecting rod 6 through the second rack; the push rod 7 is far away from the connecting rod 6 one end of the pipe penetrates through the shell to extend out and is connected with the shell in a sliding way. And the piston push rod 4 and the connecting rod 6 are both in sliding connection with the inner wall of the shell through a sliding groove mechanism.
Therefore, the push rod 7 is pulled towards the direction far away from the shell, the connecting rod 6 can be driven to move towards the direction far away from the liquid suction gear, the liquid suction gear can be driven to rotate, and the piston push rod 4 is driven to move along the direction far away from the push rod 7, so that one end of the piston push rod 4 is inserted into the capillary tube 1; pushing the push rod 7 in a direction approaching the housing can draw the piston push rod 4 out of the capillary tube 1. Thus, the push rod 7 can complete the process of sucking the liquid by the capillary tube 1 by controlling the movement of the piston push rod 4.
Referring to fig. 5 and 6, the linkage gear 5 further includes a hollow injection gear coaxially disposed with the liquid suction gear, and the injection gear is rotatably connected with the inner wall of the housing. The diameter of the liquid suction gear is smaller than the inner diameter of the injection gear, one end of the liquid suction gear is coaxially and fixedly connected with a ratchet wheel, the injection gear is sleeved outside the ratchet wheel, at least one pawl is arranged on the inner wall of the injection gear, and the pawl and the ratchet wheel form a ratchet mechanism; the pawl is rotationally connected with the inner wall of the injection gear through a torsion spring.
The injection mechanism is further arranged in the shell and comprises a pressing rod 15 and a connecting gear, a third rack is arranged in the length direction of the pressing rod 15, the pressing rod 15 is meshed with the connecting gear through the third rack, the connecting gear is meshed with the injection gear, and an included angle exists between a straight line where the length direction of the pressing rod 15 is located and the axis of the connecting rod 6. The end of the pressing rod 15 far away from the connecting gear penetrates through the shell, and the end of the pressing rod 15 far away from the connecting gear is connected with a pressing button 17 through a damping spring 16. When the pressing rod 15 is pressed downwards along the direction close to the shell, the pressing rod 15 drives the connecting gear to rotate so as to drive the injection gear to rotate, at the moment, the pawl is abutted with the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel so as to drive the ratchet wheel to rotate, and then drive the liquid suction gear to rotate, so that the piston push rod 4 moves towards the direction far away from the liquid suction gear, and injection is realized.
One end of the pressing rod 15, which is far away from the pressing button 17, is connected with a transmission piece 13 through a return spring 14, and the pressing rod 15 is fixedly connected with the return spring 14 in a coaxial way; the transmission piece 13 comprises a connecting plate arranged along the length direction of the pressing rod 15, the connecting plate is in sliding connection with the inner wall of the shell through a chute mechanism, a blocking plate is vertically fixed at one end of the connecting plate far away from the pressing button 17, the connecting plate and the blocking side form an L shape, a guide rod is vertically fixed on the blocking plate, and the guide rod axially penetrates through the reset spring 14 to be in sliding connection with the pressing rod 15.
The connecting plate is provided with the fourth rack along the length direction of the pressing rod 15, and injection mechanism still includes the adjusting gear 11 with fourth rack meshing, and adjusting gear 11 rotates with the casing to be connected, and adjusting gear 11 one end passes the coaxial fixedly connected with knob 12 of casing. The knob 12 is rotated, so that the transmission piece 13 can be driven to move, and the pressing rod 15 is driven to move, and the injection quantity is adjusted; at this time, the pawl slides over the back of the tooth-shaped protrusion on the outer peripheral surface of the ratchet wheel, and the ratchet wheel is kept stationary.
Before injection, the knob 12 is rotated to drive the connecting plate to drive the pressing rod 15 to move towards the direction away from the blocking plate, so that the maximum injection amount during one injection can be adjusted; when in injection, the pressing button 17 is pressed, the pressing rod 15 can be driven to be pressed down, so that the connecting gear is driven to rotate, the liquid suction gear is driven to rotate, the piston push rod 4 moves towards the direction far away from the liquid suction gear, and the injection can be completed; after the injection is completed, the return spring 14 drives the push rod 15 back to the position in front of the syringe for the next operation. And the return spring 14 and the damping spring 16 reduce the possibility of excessive force and improve the stability of injection.
Referring to fig. 7, the auxiliary device further includes a liquid suction amount adjusting mechanism including a threaded rod 10, a stopper 9, and an adjusting knob 8; the movable groove for inserting the threaded rod 10 is formed in the axis direction of the connecting rod 6, and the threaded rod 10 is coaxially arranged with the connecting rod 6 and is in sliding connection.
One end of the threaded rod 10, which is far away from the connecting rod 6, penetrates through the shell and is fixedly connected with the adjusting button 8, and the threaded rod 10 is rotatably connected with the shell through a bearing. The threaded rod 10 passes stopper 9 and stopper 9 threaded connection, and stopper 9 is kept away from threaded rod 10 one end protrusion in the casing, and the casing has seted up the spacing groove that supplies stopper 9 along threaded rod 10 axial motion. When the limiting block 9 is completely attached to one end of the limiting groove, which is close to the adjusting button 8, the limiting block 9 is positioned at an initial position, and at the moment, the piston push rod 4 is positioned at a critical position for completely extracting the capillary tube 1.
So, pulling push rod 7 for after piston push rod 4 one end inserts in the capillary 1 completely, rotate adjusting knob 8, can adjust the distance between stopper 9 and the connecting rod 6, thereby control push rod 7 is towards the distance that is close to the casing direction motion, and then realize the regulation to the interior liquid absorption volume of capillary 1.
In addition, the corresponding position of the shell and the limiting block 9 is provided with scales by combining with an internal structure, the peripheral surface of the push rod 7 and the surface of the knob 12 are also provided with scales by combining with the internal structure, and the scales at the knob 12 are used for intuitively and accurately displaying and controlling the quantity of injection liquid; the scales on the outer peripheral surface of the push rod 7 and the scales on the corresponding positions of the shell and the limiting block 9 are matched to intuitively and accurately display and control the amount of liquid sucked.
The implementation principle of the microinjection auxiliary device is as follows: before use, the capillary tube 1 is fixed with the shell by adopting the reverse taper silica gel sleeve 3 and the fixing cap 2, the push rod 7 is pulled to enable the push rod 7 to move along the direction far away from the shell, and the liquid suction gear can be driven to rotate by the connecting rod 6, so that the piston push rod 4 is driven to be inserted into the capillary tube 1, and preparation before liquid suction is carried out;
the adjusting button 8 is rotated, so that the limiting block 9 moves towards the direction close to the push rod 7, and the distance between the limiting block 9 and the connecting rod 6 is adjusted, so that the distance of the push rod 7 moving towards the direction close to the shell is adjusted, the retreating distance of the piston push rod 4 moving towards the direction close to the liquid suction gear can be controlled, and the liquid suction amount is adjusted; after the adjustment of the liquid suction amount is completed, pushing the push rod 7 towards the direction close to the shell until one end of the connecting rod 6 is attached to the limiting block 9, so that liquid suction can be realized;
Before the injector, the knob 12 is rotated, the driving piece 13 drives the pressing rod 15 to lift the pressing rod 15 towards a direction away from the shell, so that the maximum injection quantity of one injection is adjusted, at the moment, the pawl slides over the back of the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel, and the ratchet wheel is kept still; when in injection, the pressing button 17 is pressed down, the pressing rod 15 can be driven to be pressed down, so that the injection gear is driven to rotate through the connecting gear, at the moment, the pawl is abutted with the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel, so that the ratchet wheel is driven to rotate, the liquid suction gear is driven to rotate, and the piston push rod 4 moves towards the direction far away from the liquid suction gear, so that injection can be realized; the return spring 14 and the damper spring 16 reduce the potential for excessive force during injection by the operator and improve the stability of the injection during injection.
In conclusion, the appearance of the shell body is similar to a cuboid structure, and a mechanical transmission module is arranged in the shell body; the single hand holds the utility model, which accords with the finger structure of human body, is convenient and practical, and has beautiful appearance. The injection time is as follows: the quantitative liquid can be sucked once, and then the liquid is injected for a plurality of times in a small amount; the liquid suction mechanism, the injection mechanism and the liquid suction amount adjusting structure are all realized by adopting a mode of combining a metal rod and a gear, so that the stability is high and the adjustability is high. The invention uses the cooperation of the injection gear and the ratchet wheel in the linkage gear 5, thereby being convenient for carrying out small-dose injection for many times. The connecting pipe is matched with the fixing cap 2, so that the pressurizing and fixing of the inverted cone-shaped silica gel sleeve 3 are realized, and the tightness and stability of the capillary tube 1 are ensured.
Therefore, the microinjection auxiliary device effectively solves the problems that the pressure is difficult to control, the accurate calibration scale is not available, the sucking and injecting amount is difficult to control, the operation is complex during injection and the like when the microinjection needle is used.

Claims (7)

1. A microinjection assisting apparatus, characterized in that: the device comprises a cuboid shell, wherein a liquid suction mechanism and an injection mechanism are arranged in the shell, a fixing piece is arranged at one end of the shell in the length direction, and the shell is detachably connected with one end of a capillary tube (1) through the fixing piece;
the liquid suction mechanism comprises a linkage gear (5), a piston push rod (4) and a connecting rod (6) which are arranged in parallel, and the piston push rod (4) and the connecting rod (6) are both in sliding connection with the inner wall of the shell; the piston push rod (4) is coaxially arranged with the capillary tube (1), and a first rack is arranged at one end, far away from the capillary tube (1), of the piston push rod (4) in the length direction; a second rack is arranged at one end, close to the capillary tube (1), of the connecting rod (6) in the length direction;
The linkage gear (5) comprises a liquid suction gear which is rotationally connected with the inner wall of the shell, the liquid suction gear is positioned between the piston push rod (4) and the connecting rod (6), and the liquid suction gear is meshed with the piston push rod (4) through a first rack and is meshed with the connecting rod (6) through a second rack; the connecting rod (6) moves along the direction away from the capillary tube (1), and the liquid suction gear drives one end of the piston push rod (4) away from the liquid suction gear to be inserted into the capillary tube (1);
The linkage gear (5) further comprises a hollow injection gear coaxially arranged with the liquid suction gear, one end of the liquid suction gear is coaxially and fixedly connected with a ratchet wheel, the injection gear is sleeved outside the ratchet wheel, at least one pawl is arranged on the inner wall of the injection gear, and the pawl and the ratchet wheel form a ratchet mechanism; the pawl is rotationally connected with the inner wall of the injection gear through a torsion spring; the injection gear and the ratchet wheel are both rotationally connected with the inner wall of the shell;
The injection mechanism comprises a pressing rod (15) which is in sliding connection with the shell and a connecting gear which is meshed with the injection gear, a third rack is arranged in the length direction of the pressing rod (15), the third rack is meshed with the connecting gear, and one end, far away from the connecting gear, of the pressing rod (15) penetrates through the shell to extend out; when the pressing rod (15) moves along the direction approaching to the connecting gear, the pawl is abutted with the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel to drive the ratchet wheel to rotate, and at the moment, the liquid suction gear rotates along with the ratchet wheel to drive the piston push rod (4) to move towards the direction far away from the liquid suction gear; when the pressing rod (15) moves along the direction away from the connecting gear, the pawl slides over the back of the tooth-shaped bulge on the outer peripheral surface of the ratchet wheel, and the ratchet wheel is kept stationary.
2. A microinjection assisting apparatus according to claim 1, characterized in that the end of the connecting rod (6) remote from the capillary tube (1) is coaxially connected with a push rod (7), and the end of the push rod (7) remote from the connecting rod (6) extends through the housing and is slidably connected with the housing.
3. A microinjection assisting apparatus according to claim 1, characterized in that the end of the pressing rod (15) remote from the connecting gear is connected with a pressing button (17) through a damping spring (16).
4. A microinjection auxiliary device according to claim 3, characterized in that the end of the pressing rod (15) far away from the pressing button (17) is connected with a transmission member (13) through a return spring (14), and the pressing rod (15) is fixedly connected with the return spring (14) coaxially;
The transmission part (13) comprises a connecting plate arranged along the length direction of the pressing rod (15), and the connecting plate is in sliding connection with the inner wall of the shell; a blocking plate is vertically fixed at one end, far away from the pressing button (17), of the connecting plate, a guide rod is vertically fixed on the blocking plate, and the guide rod axially penetrates through the reset spring (14) to be in sliding connection with the pressing rod (15);
The connecting plate is provided with a fourth rack along the length direction of the pressing rod (15), the injection mechanism further comprises an adjusting gear (11) meshed with the fourth rack, the adjusting gear (11) is rotationally connected with the shell, and one end of the adjusting gear (11) penetrates through the shell to be coaxially fixed with a knob (12).
5. A microinjection auxiliary device according to claim 1, further comprising a liquid suction amount adjusting mechanism, wherein the liquid suction amount adjusting mechanism comprises a threaded rod (10) coaxially arranged with the connecting rod (6), a movable groove for inserting the threaded rod (10) is formed in the axis direction of the connecting rod (6), one end of the threaded rod (10) is in sliding connection with the connecting rod (6), and the other end of the threaded rod is in rotating connection with the shell;
One end of the threaded rod (10) far away from the connecting rod (6) penetrates through the shell to be fixedly connected with an adjusting button (8); threaded rod (10) threaded connection has stopper (9), stopper (9) are located between adjusting knob (8) and connecting rod (6), and stopper (9) are kept away from threaded rod (10) one end protrusion in the casing, and the spacing groove that supplies stopper (9) along threaded rod (10) axial motion is seted up to the casing.
6. A microinjection auxiliary device according to claim 1, characterized in that the fixing part comprises a fixing cap (2) and an inverse cone-shaped silica gel sleeve (3) for the capillary tube (1) to axially pass through, wherein the inverse cone-shaped silica gel sleeve (3) is wrapped on the outer wall of the capillary tube (1) and is detachably connected with the capillary tube (1);
The utility model discloses a shell, including casing length direction one end is provided with and supplies reverse taper silica gel cover (3) male connecting pipe, and the less one end of reverse taper silica gel cover (3) diameter towards the casing, connecting pipe outer wall and fixed cap (2) inner wall threaded connection, when connecting pipe and fixed cap (2) are connected, connecting pipe clamp reverse taper silica gel cover (3).
7. Microinjection aid according to claim 1, characterized in that the housing is provided with a catch (18) for holding a finger.
CN202211723328.7A 2022-12-30 2022-12-30 Microinjection auxiliary device Active CN116212162B (en)

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CN1168639A (en) * 1994-12-09 1997-12-24 米奇弗琴特科技生产联合体 Syringe
CN112773979A (en) * 2021-02-04 2021-05-11 中国人民解放军总医院第一医学中心 Quantitative injector

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Publication number Priority date Publication date Assignee Title
JP4350525B2 (en) * 2002-03-18 2009-10-21 イーライ リリー アンド カンパニー Drug dispensing device with gear set giving mechanical advantages
US10213555B1 (en) * 2015-06-17 2019-02-26 Irina M Carranza Syringe having a mechanically operated mechanism for injecting precise volumes of a solution
CN211584687U (en) * 2019-12-21 2020-09-29 北京鑫禾丰医疗技术有限公司 Micro-injection pump propulsion structure
CN215275092U (en) * 2021-04-27 2021-12-24 周雨胜 Adjustable continuous quantitative injector

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1168639A (en) * 1994-12-09 1997-12-24 米奇弗琴特科技生产联合体 Syringe
CN112773979A (en) * 2021-02-04 2021-05-11 中国人民解放军总医院第一医学中心 Quantitative injector

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