CN115644943A - A clinical sample collection and temporary storage inspection box for bone tumors - Google Patents
A clinical sample collection and temporary storage inspection box for bone tumors Download PDFInfo
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- 238000007689 inspection Methods 0.000 title claims abstract description 52
- 208000018084 Bone neoplasm Diseases 0.000 title claims abstract description 13
- 238000005070 sampling Methods 0.000 claims abstract description 79
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- 238000003825 pressing Methods 0.000 claims description 8
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical group [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
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- 206010005949 Bone cancer Diseases 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 abstract description 31
- 206010035226 Plasma cell myeloma Diseases 0.000 abstract description 29
- 201000000050 myeloid neoplasm Diseases 0.000 abstract description 29
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- 238000009423 ventilation Methods 0.000 description 4
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Abstract
本发明提供一种骨肿瘤临床用样本采集与临时储存送检盒,解决了在对患者进行骨髓瘤取样过程,穿刺取样造成骨髓瘤样本采集太少,在采集过程出现空采,采样后需要样本组织暴露短时间暴露外界的问题;本发明包括送检盒,送检盒下端开设有贯穿孔,贯穿孔上端同轴固定连接有定位筒,定位筒下端同轴连接有穿刺针,穿刺针为中空结构,穿刺针下端开设有通孔,定位筒内上下滑动连接有切割筒,切割筒上方连接有升降活塞筒,升降活塞筒上端固定连接有磁铁盘,升降活塞筒上端连接有升降架,升降架下端固定连接有和磁铁盘相配合的磁铁环,升降活塞上端同轴固定连接有提拉绳,提拉绳贯穿升降架;本发明结构精巧,具有很强的实用性。The invention provides a bone tumor clinical sample collection and temporary storage inspection box, which solves the problem of too little myeloma sample collection caused by puncture sampling during the myeloma sampling process of patients, empty sampling occurs during the collection process, and samples are required after sampling The problem of tissue exposure to the outside world for a short time; the invention includes a test box, a through hole is opened at the lower end of the test box, a positioning cylinder is fixedly connected to the upper end of the through hole, and a puncture needle is coaxially connected to the lower end of the positioning cylinder, and the puncture needle is hollow Structure, the lower end of the puncture needle is provided with a through hole, the positioning cylinder slides up and down to connect with the cutting cylinder, the upper end of the cutting cylinder is connected with the lifting piston cylinder, the upper end of the lifting piston cylinder is fixedly connected with the magnet disk, the upper end of the lifting piston cylinder is connected with the lifting frame, the lifting frame The lower end is fixedly connected with a magnet ring matched with the magnet disk, and the upper end of the lifting piston is coaxially fixedly connected with a lifting rope, and the lifting rope runs through the lifting frame; the structure of the present invention is exquisite and has strong practicability.
Description
技术领域technical field
本发明涉及肿瘤样本采集及储存设备技术领域,具体是一种骨肿瘤临床用样本采集与临时储存送检盒。The invention relates to the technical field of tumor sample collection and storage equipment, in particular to a bone tumor clinical sample collection and temporary storage inspection box.
背景技术Background technique
在骨髓瘤的诊断治疗过程,首先需要对骨髓瘤进行诊断,确认患者得的是否为骨髓瘤,在诊断过程中,对骨髓瘤进行组织切除,然后对切除的组织样本进行检测分析,是一种较为准确的诊疗方式。In the diagnosis and treatment of myeloma, it is first necessary to diagnose myeloma to confirm whether the patient has myeloma. During the diagnosis process, the myeloma tissue is excised, and then the excised tissue samples are tested and analyzed. more accurate diagnosis.
但是目前在对患者进行骨髓瘤诊断切片分析过程,大多数采用穿刺针对患处进行穿刺,然后在通过留在穿刺针内的骨髓瘤组织,进行活检,但是在骨髓瘤组织采集和送检的过程,易出现骨髓瘤组织采样太少、在穿刺针拔出的过程骨髓瘤组织脱落,造成取样失败、骨髓瘤在采样完成后需要与外界环境接触,增大了外界环境对检测精准性的影响,同时在送检的过程不能很好地避免外界环境影响。However, in the current process of analyzing myeloma diagnostic slices for patients, most of them use puncture to puncture the affected area, and then perform biopsy through the myeloma tissue left in the puncture needle, but in the process of myeloma tissue collection and inspection, It is easy to have too little myeloma tissue sampling, and the myeloma tissue falls off during the process of pulling out the puncture needle, resulting in sampling failure. Myeloma needs to be in contact with the external environment after sampling, which increases the impact of the external environment on the detection accuracy. In the process of sending for inspection, the influence of the external environment cannot be well avoided.
因此,本发明提供一种骨肿瘤临床用样本采集与临时储存送检盒来解决上述问题。Therefore, the present invention provides a bone tumor clinical sample collection and temporary storage inspection box to solve the above problems.
发明内容Contents of the invention
针对上述情况,为克服现有技术之缺陷,本发明提供一种骨肿瘤临床用样本采集与临时储存送检盒,有效的解决了在对患者进行骨髓瘤取样过程,穿刺取样造成骨髓瘤样本采集太少,在采集过程出现空采,采样后需要样本组织暴露短时间暴露外界以及不能实现采样送检一体化操作的问题。In view of the above situation, in order to overcome the defects of the prior art, the present invention provides a bone tumor clinical sample collection and temporary storage inspection box, which effectively solves the problem of myeloma sample collection caused by puncture sampling during the myeloma sampling process of patients. Too little, there will be empty sampling during the collection process, the sample tissue needs to be exposed to the outside world for a short time after sampling, and the integrated operation of sampling and inspection cannot be realized.
本发明包括送检盒,所述的送检盒下端开设有贯穿孔,所述的贯穿孔上端同轴固定连接有定位筒,所述的定位筒下端同轴连接有穿刺针,所述的穿刺针为中空结构,所述的穿刺针下端开设有通孔,所述的定位筒内上下滑动连接有切割筒,所述的切割筒上方连接有升降活塞筒,所述的升降活塞筒上端固定连接有磁铁盘,所述的升降活塞筒上端连接有升降架,所述的升降架下端固定连接有和所述的磁铁盘相配合的磁铁环,所述的升降活塞上端同轴固定连接有提拉绳,所述的提拉绳贯穿所述的升降架,所述的提拉绳另一端和转动连接在所述的送检盒内的单向线轮相连,所述的单向线轮和转动连接在所述的送检盒内部的驱动轴同轴相连,所述的驱动轴和固定连接在所述的送检盒内部的驱动电机相连;The present invention includes an inspection box, the lower end of the inspection box is provided with a through hole, the upper end of the through hole is coaxially fixedly connected with a positioning cylinder, and the lower end of the positioning cylinder is coaxially connected with a puncture needle, and the puncture The needle is a hollow structure, the lower end of the puncture needle is provided with a through hole, the positioning cylinder is connected with a cutting cylinder sliding up and down, the lifting piston cylinder is connected above the cutting cylinder, and the upper end of the lifting piston cylinder is fixedly connected There is a magnet plate, the upper end of the lifting piston cylinder is connected with a lifting frame, the lower end of the lifting frame is fixedly connected with a magnet ring matching the magnet plate, and the upper end of the lifting piston is coaxially fixedly connected with a lifting frame. Rope, the lifting rope runs through the lifting frame, the other end of the lifting rope is connected to the one-way wire wheel that is rotatably connected in the inspection box, and the one-way wire wheel is connected to the rotating The drive shaft connected to the inside of the inspection box is connected coaxially, and the drive shaft is connected to the drive motor fixedly connected to the inside of the inspection box;
所述的送检盒内固定连接有气泵,所述的气泵下端固定连接有气缸套,所述的气缸套内上下滑动连接有U形管,所述的U形管上端和所述的升降架固定连接,所述的升降架固定连通有进气管,所述的进气管和所述的U形管相连通;An air pump is fixedly connected to the inspection box, a cylinder liner is fixedly connected to the lower end of the air pump, and a U-shaped tube is slid up and down inside the cylinder liner, and the upper end of the U-shaped tube is connected to the lifting frame. Fixedly connected, the lift frame is fixedly communicated with an air intake pipe, and the air intake pipe communicates with the U-shaped pipe;
所述的U形管置于所述的气缸套一端内部固定连接有压力进气阀,所述的压力进气阀包括和所述的U形管固定连接的外环套管,所述的外环套管内部同轴固定连接有进气阀套,所述的进气阀套下侧开设有若干通气框,所述的进气阀套内部同轴上下滑动连接有升降压力活塞,所述的升降压力活塞下端通过弹簧和所述的进气阀套相连。The U-shaped tube is placed inside one end of the cylinder liner and is fixedly connected with a pressure intake valve. The pressure intake valve includes an outer ring sleeve fixedly connected with the U-shaped tube. The inside of the ring sleeve is coaxially fixedly connected with an intake valve sleeve, and the lower side of the intake valve sleeve is provided with a number of ventilation frames, and the inside of the intake valve sleeve is coaxially slid up and down and connected with a lifting pressure piston. The lower end of the lifting pressure piston is connected with the intake valve sleeve through a spring.
优选的,所述的贯穿孔下端固定连接有紧固外螺纹套,所述的穿刺针贯穿所述的紧固外螺纹套,所述的紧固外螺纹套下端径向滑动连接有若干等间距分布的紧固弧形板,所述的紧固弧形板下端均开设有弧形轨道,所述的弧形轨道内滑动连接有滑动伸缩杆,所述的滑动伸缩杆和螺纹连接在所述的紧固外螺纹套外围的紧固螺母套固定连接。Preferably, the lower end of the through hole is fixedly connected with a fastening external thread sleeve, the puncture needle passes through the fastening external thread sleeve, and the lower end of the fastening external thread sleeve is radially slidably connected with several equidistant Distributed fastening arc-shaped plates, the lower ends of the fastening arc-shaped plates are provided with arc-shaped tracks, and sliding telescopic rods are slidably connected in the arc-shaped rails, and the sliding telescopic rods and threaded connections are connected to the The fastening nut sleeve on the periphery of the fastening external thread sleeve is fixedly connected.
优选的,所述的切割筒内同轴置有载物盘,所述的载物盘上端固定连接有铁质环,所述的载物盘上固定连接有红外接收器;Preferably, a loading tray is coaxially placed inside the cutting cylinder, an iron ring is fixedly connected to the upper end of the loading tray, and an infrared receiver is fixedly connected to the loading tray;
所述的切割筒右侧固定连接有隔板,所述的隔板右端转动连接有往复丝杠,所述的往复丝杠和转动连接在所述的送检盒内部的转动套筒转动连接,所述的往复丝杠和固定连接在所述的转动套筒内的取样电机相连,所述的转动套筒和固定连接在所述的送检盒内的支撑圆盘转动连接,所述的转动套筒内部固定连接有和所述的往复丝杠位置对称的限位杆,所述的限位杆上左右滑动连接有试管支撑架,所述的试管支撑架右端和所述的转动套筒通过弹簧相连,所述的试管支撑架上端固定连接有试管限位套,所述的试管限位套内置有取样试管,所述的往复丝杠上螺纹连接有和所述的转动套筒左右滑动连接的取样架,所述的隔板上开设有和所述的取样架相配合的取样窗,所述的取样架下端固定连接有和所述的铁质环相配合的环形电磁铁,所述的取样架下端固定连接有和所述的红外接收器相配合的红外发射器,所述的红外接收器和所述的环形电磁铁相连;The right side of the cutting cylinder is fixedly connected with a partition, and the right end of the partition is rotatably connected with a reciprocating screw, and the reciprocating screw is rotatably connected to the rotating sleeve inside the inspection box. The reciprocating lead screw is connected to the sampling motor fixedly connected in the rotating sleeve, and the rotating sleeve is connected to the support disc fixedly connected in the inspection box, and the rotating The inside of the sleeve is fixedly connected with a limit rod that is symmetrical to the position of the reciprocating screw. The test tube support frame is slidably connected to the left and right sides of the limit rod. The right end of the test tube support frame and the rotating sleeve pass through The upper end of the test tube support frame is fixedly connected with a test tube stopper, and the test tube stopper is built with a sampling test tube. The sampling rack, the said dividing plate is provided with the sampling window matched with the said sampling rack, the lower end of the said sampling rack is fixedly connected with the annular electromagnet matched with the said iron ring, said The lower end of the sampling frame is fixedly connected with an infrared emitter matched with the infrared receiver, and the infrared receiver is connected with the ring electromagnet;
所述的转动套筒内部开设有滑行轨道,所述的滑行轨道左端固定连通有滑行直轨,所述的滑行直轨滑动连接有和所述的取样架固定连接的滑行销;The inside of the rotating sleeve is provided with a sliding track, the left end of the sliding track is fixedly connected with a sliding straight rail, and the sliding straight rail is slidably connected with a sliding pin fixedly connected with the sampling rack;
所述的送检盒下端固定连接有和所述的试管支撑架相配合试管加持装置。The lower end of the test delivery box is fixedly connected with a test tube holding device matched with the test tube support frame.
优选的,所述的升降活塞筒内部上下滑动连接有转动轴杆,所述的转动轴干上开设有滑动螺纹轨,所述的升降活塞筒内部固定连接有和所述的滑动螺纹轨相配合的滑动销;Preferably, the inside of the lifting piston barrel is slidably connected with a rotating shaft rod up and down, and a sliding threaded rail is provided on the stem of the rotating shaft, and the inside of the lifting piston barrel is fixedly connected with a sliding threaded rail that matches the sliding threaded rail. the sliding pin;
所述的转动轴干下端和所述的切割筒固定连接,所述的切割筒下端轴心处转动连接有转动球,所述的切割筒下端一侧固定连接有L形杆,所述的穿刺针内部低端开设有和所述的L形杆相配合的倒L形限位弧形轨;The lower end of the rotating shaft is fixedly connected to the cutting cylinder, a rotating ball is rotatably connected to the shaft center of the lower end of the cutting cylinder, an L-shaped rod is fixedly connected to one side of the lower end of the cutting cylinder, and the puncture The inner low end of the needle is provided with an inverted L-shaped limit arc rail matched with the L-shaped rod;
所述的定位筒侧壁固定连接有两个对称分布的弧形限位块,所述的定位筒和穿刺针均开设有和所述的弧形限位块相配合的弧形限位轨。Two symmetrically distributed arc-shaped limiting blocks are fixedly connected to the side wall of the positioning cylinder, and both the positioning cylinder and the puncture needle are provided with arc-shaped limiting rails matched with the arc-shaped limiting blocks.
优选的,所述的试管限位套包括和所述的试管支撑架固定连接的左半环套,所述的左半环套右侧置有和所述的试管支撑架左右滑动的右半环套,所述的右半环套右端固定连接有矩形磁铁,所述的试管支撑架右侧上端固定连接有矩形电磁铁,所述的矩形电磁铁外界电源。Preferably, the test tube stop cover includes a left half ring fixedly connected to the test tube support frame, and a right half ring that slides left and right with the test tube support frame is arranged on the right side of the left half ring cover. The right end of the right half-ring sleeve is fixedly connected with a rectangular magnet, the upper end of the right side of the test tube support frame is fixedly connected with a rectangular electromagnet, and the external power supply of the rectangular electromagnet.
优选的,所述的试管加持装置包括和所述的送检盒固定连接的承托架,所述的承托架上端前后两侧对称置有加持条,所述的加持条君合所述的承托架前后滑动连接,所述的加持条和所述的承托架通过弹簧相连;Preferably, the test tube holding device includes a support bracket fixedly connected to the inspection box, and the front and rear sides of the upper end of the support bracket are symmetrically provided with support strips, and the support strips are consistent with the above-mentioned The supporting frame is slidingly connected front and back, and the said reinforcing bar is connected with the said supporting frame through a spring;
所述的加持条右侧下端均固定连接有滑动推板,所述的承托架开设有和所述的滑动推板相配合的滑行仓,所述的滑行仓内均固定连接有伸缩液压杆,两个所述的伸缩液压杆和固定连接在所述的承托架上的进油弯管通过三通管相连通,所述的进油弯管后端前后滑动连接有按压活塞杆,所述的按压活塞杆后端固定连接有滑动杆,所述的滑动杆和前后滑动连接在所述的承托架上的矩形滑套固定连接;The lower end of the right side of the support bar is fixedly connected with a sliding push plate, and the support frame is provided with a sliding chamber that matches the sliding push plate, and a telescopic hydraulic rod is fixedly connected in the sliding chamber , the two telescopic hydraulic rods and the oil inlet elbow fixedly connected to the support bracket are connected through a three-way pipe, and the rear end of the oil inlet elbow is slidingly connected with a pressing piston rod back and forth, so The rear end of the pressing piston rod is fixedly connected with a sliding rod, and the sliding rod is fixedly connected with the rectangular sliding sleeve slidingly connected front and rear on the support bracket;
所述的矩形滑套内上下滑动连接有限位楔形板,所述的限位楔形板下端和所述的矩形滑套通过弹簧相连;The limiting wedge plate is slid up and down inside the rectangular sliding sleeve, and the lower end of the limiting wedge plate is connected to the rectangular sliding sleeve through a spring;
所述的转动套筒外壁同轴固定连接有驱动环,所述的驱动环上固定连接有驱动杆架,所述的驱动杆架上转动连接有驱动轮。A drive ring is coaxially and fixedly connected to the outer wall of the rotating sleeve, a drive rod frame is fixedly connected to the drive ring, and a drive wheel is rotatably connected to the drive rod frame.
优选的,所述的送检盒内部上端固定连接有若干UV杀菌灯,所述的送检盒内固定连接有智能温控器。Preferably, several UV germicidal lamps are fixedly connected to the upper end of the inspection delivery box, and an intelligent temperature controller is fixedly connected to the inspection delivery box.
优选的,所述的送检盒上固定连接有控制模块,所述的控制模块内部集成有控制单元,所述的红外发射器、红外接收器、驱动电机、取样电机、气泵、环形电磁铁、矩形电磁铁、UV杀菌灯和智能温控器均和所述的控制模块相连。Preferably, a control module is fixedly connected to the inspection box, and a control unit is integrated inside the control module, and the infrared emitter, infrared receiver, driving motor, sampling motor, air pump, ring electromagnet, The rectangular electromagnet, the UV germicidal lamp and the intelligent temperature controller are all connected with the control module.
本发明针对现有的骨髓瘤样本采集和送检盒进行改进,通过增设穿刺针、通孔、切割筒、升降活塞筒、磁铁盘、升降架、磁铁环、气泵、U形管、压力进气阀、提拉绳和单向线轮以及驱动电机有效的解决了对患者进行穿刺过程保证骨髓瘤组织能够顺利切除以及在输送过程不至于脱落的问题;通过设置紧固外螺纹套、紧固弧形板、弧形轨道和滑动伸缩杆以及紧固螺母套有效的解决了对穿刺针进行有效固定加持的问题;通过设置载物盘、往复丝杠、转动套筒、取样架、试管支撑架、取样试管、滑行轨道和取样电机有效地解决了对将样本组织置于取样试管内部,以及将取样试管进行翻转收纳的问题;通过设置转动轴杆、滑动螺纹轨、滑动销、L形杆和L形限位弧形轨有效地实现了对切割筒进行转动实现对通孔进行密封和打开,保证骨髓瘤组织更好地进入穿刺针内部的问题;通过设置承托架、加持条、滑动推板、滑行仓和伸缩液压杆有效的解决了对取样试管进行限位加持的问题;通过设置UV杀菌灯和智能温控器有效的解决了对样本进行低温无菌防护的问题;且结构简洁稳定,具有极高的普适性。The present invention improves the existing myeloma sample collection and inspection box by adding a puncture needle, a through hole, a cutting cylinder, a lifting piston cylinder, a magnet plate, a lifting frame, a magnet ring, an air pump, a U-shaped tube, and a pressure intake The valve, the lifting rope, the one-way wire wheel and the driving motor effectively solve the problem of ensuring the smooth resection of the myeloma tissue during the puncture process of the patient and the problem that the myeloma tissue will not fall off during the delivery process; Shaped plate, arc-shaped track, sliding telescopic rod and fastening nut sleeve effectively solve the problem of effectively fixing and supporting the puncture needle; by setting the loading plate, reciprocating screw, rotating sleeve, sampling rack, test tube The sampling test tube, sliding track and sampling motor effectively solve the problem of placing the sample tissue inside the sampling test tube and flipping and storing the sampling test tube; The arc-shaped rail of the shape limit can effectively realize the rotation of the cutting cylinder to seal and open the through hole, so as to ensure that the myeloma tissue can better enter the inside of the puncture needle; , the sliding chamber and the telescopic hydraulic rod effectively solve the problem of limiting the sampling tube; by setting the UV germicidal lamp and the intelligent temperature controller, the problem of low-temperature aseptic protection for the sample is effectively solved; and the structure is simple and stable, It has high universality.
附图说明Description of drawings
图1为本发明立体示意图。Fig. 1 is a schematic perspective view of the present invention.
图2为本发明剖视示意图。Fig. 2 is a schematic cross-sectional view of the present invention.
图3为本发明送检盒内部结构立体图。Fig. 3 is a perspective view of the internal structure of the inspection box of the present invention.
图4为本发明切割筒升降驱动结构局部示意图。Fig. 4 is a partial schematic diagram of the lifting and lowering driving structure of the cutting cylinder of the present invention.
图5为本发明样本组织收纳结构局部示意图。Fig. 5 is a partial schematic diagram of the sample tissue storage structure of the present invention.
图6为本发明穿刺针内部结构剖视示意图。Fig. 6 is a schematic cross-sectional view of the internal structure of the puncture needle of the present invention.
图7为本发明压力进气阀内部结构示意图。Fig. 7 is a schematic diagram of the internal structure of the pressure intake valve of the present invention.
图8为本发明取样试管转动翻转结构示意图。Fig. 8 is a schematic diagram of the rotating and flipping structure of the sampling test tube of the present invention.
图9为本发明加持条驱动结构示意图。Fig. 9 is a schematic diagram of the drive structure of the brace bar of the present invention.
图10为本发明切割筒转动驱动结构示意图。Fig. 10 is a schematic diagram of the rotation driving structure of the cutting cylinder of the present invention.
图11为本发明取样结构剖视示意图。Fig. 11 is a schematic cross-sectional view of the sampling structure of the present invention.
图12为本发明L形限位弧形轨立体示意图。Fig. 12 is a three-dimensional schematic view of the L-shaped limiting arc rail of the present invention.
图13位本发明转动套筒内部结构示意图。Fig. 13 is a schematic diagram of the internal structure of the rotating sleeve of the present invention.
其中,1、送检盒;2、贯穿孔;3、定位筒;4、穿刺针;5、通孔;6、切割筒;7、升降活塞筒;8、磁铁盘;9、升降架;10、磁铁环;11、提拉绳;12、单向线轮;13、驱动轴;14、驱动电机;15、气泵;16、气缸套;17、U形管;18、进气管;19、外环套管;20、进气阀套21、通气框;22、升降压力活塞;23、紧固外螺纹套;24、紧固弧形板;25、弧形轨道;26、滑动伸缩杆;27、紧固螺母套;28、载物盘;29、铁质环;30隔板;31、往复丝杠;32、转动套筒;33、取样电机;34、支撑圆盘;35、限位杆;36、试管支撑架;37、取样试管;38、取样架;39、取样窗;41、滑行轨道;42、滑行直轨;43、滑行销;44、转动轴杆;45、滑动螺纹轨;46、转动球;47、L形杆;48、L形限位弧形轨;49、弧形限位块;50、弧形限位轨;51、左半环套;52、右半环套;53、矩形磁铁;54、矩形电磁铁;55、承托架;56、加持条;57、滑动推板;58、滑行仓;59、伸缩液压杆;60、进油弯管;61、按压活塞杆;62、滑动杆;63、矩形滑套;64、限位楔形板;65、驱动环;66、驱动轮;67、驱动杆架;68、UV杀菌灯;69、智能温控器;70、控制模块。Among them, 1. Inspection box; 2. Through hole; 3. Positioning cylinder; 4. Puncture needle; 5. Through hole; 6. Cutting cylinder; 7. Lifting piston cylinder; 8. Magnet plate; , magnet ring; 11, pull rope; 12, one-way wire wheel; 13, drive shaft; 14, drive motor; 15, air pump; 16, cylinder liner; 17, U-shaped pipe; 18, intake pipe; Ring casing; 20, intake valve sleeve 21, ventilation frame; 22, lifting pressure piston; 23, fastening external thread sleeve; 24, fastening arc plate; 25, arc track; 26, sliding telescopic rod; 27 , fastening nut cover; 28, loading tray; 29, iron ring; 30 partition; 31, reciprocating screw; 32, rotating sleeve; 33, sampling motor; 34, support disc; 35, limit rod ; 36, test tube support frame; 37, sampling test tube; 38, sampling rack; 39, sampling window; 41, sliding track; 42, sliding straight rail; 43, sliding pin; 44, rotating shaft rod; 45, sliding thread rail; 46, rotating ball; 47, L-shaped rod; 48, L-shaped limit arc rail; 49, arc limit block; 50, arc limit rail; 51, left half ring sleeve; 52, right half ring sleeve ;53, rectangular magnet; 54, rectangular electromagnet; 55, supporting bracket; 56, holding bar; 57, sliding push plate; Piston rod; 62, sliding rod; 63, rectangular sliding sleeve; 64, limit wedge plate; 65, driving ring; 66, driving wheel; 67, driving rod frame; 68, UV germicidal lamp; 69, intelligent temperature controller; 70. Control module.
具体实施方式Detailed ways
有关本发明的前述及其他技术内容、特点与功效,在以下配合参考附图1至图13对实施例的详细说明中,将可清楚的呈现。以下实施例中所提到的结构内容,均是以说明书附图为参考。The aforementioned and other technical contents, features and effects of the present invention will be clearly presented in the following detailed description of the embodiments with reference to the accompanying drawings 1 to 13 . The structural contents mentioned in the following embodiments are all based on the accompanying drawings of the description.
下面将参照附图描述本发明的各示例性的实施例。Exemplary embodiments of the present invention will be described below with reference to the accompanying drawings.
实施例一,本发明为一种骨肿瘤临床用样本采集与临时储存送检盒,包括送检盒1,所述的送检盒1上端固定连接有转动手柄,通过转动手柄的转动带动所述的送检盒1转动,所述的送检盒1内部固定连接有蓄电池,所述的蓄电池为后续结构提供电源,所述的送检盒1下端开设有贯穿孔2,所述的贯穿孔2上端同轴固定连接有定位筒3,所述的转动手柄和所述的贯穿孔2、定位筒3同轴,所述的定位筒3下端同轴连接有穿刺针4,所述的穿刺针4和所述的定位筒3在本实施例中通过螺纹连接,所述的穿刺针4为中空结构,所述的穿刺针4下端侧壁开设有通孔5,骨髓瘤组织通过所述的通孔5进入所述的穿刺针4内部,便于后续将进入所述的穿刺针4内部的骨髓瘤组织进行切除,所述的定位筒3内上下滑动连接有切割筒6,所述的切割筒6上方连接有升降活塞筒7,在本实施例中所述的切割筒6和所述的升降活塞筒7固定连接,所述的升降活塞筒7上端固定连接有磁铁盘8,所述的升降活塞筒7上端连接有升降架9,所述的升降架9下端固定连接有和所述的磁铁盘8相配合的磁铁环10,通过所述的磁铁环10和磁铁盘8的相互吸引,实现所述的升降架9和所述的升降活塞筒7的连接,所述的升降活塞上端同轴固定连接有提拉绳11,所述的提拉绳11贯穿所述的升降架9,所述的提拉绳11另一端和转动连接在所述的送检盒1内的单向线轮12相连,同时所述的提拉绳11绕过转动连接在所述的送检盒1内部的导向轮,然后缠绕在所述的单向线轮12上,所述的单向线轮12为现有的单向轮,所述的单向线轮12和转动连接在所述的送检盒1内部的驱动轴13同轴相连,所述的驱动轴13和固定连接在所述的送检盒1内部的驱动电机14相连,在对所述的升降活塞筒7进行提升的过程,所述的驱动电机14转动带动所述的单向线轮12同步转动,在所述的升降活塞筒7下降时,所述的单向线轮12空转,保证所述的提拉绳11和所述的升降活塞筒7同步滑动;Embodiment 1, the present invention is a clinical sample collection and temporary storage inspection box for bone tumors, including an inspection box 1, the upper end of the inspection box 1 is fixedly connected with a rotating handle, and the rotation of the rotating handle drives the inspection box 1. The inspection box 1 rotates, and the interior of the inspection box 1 is fixedly connected with a battery, and the battery provides power for the subsequent structure. The lower end of the inspection box 1 is provided with a through
所述的送检盒1内固定连接有气泵15,所述的气泵15下端固定连接有气缸套16,所述的气缸套16内上下滑动连接有U形管17,所述的U形管17上端和所述的升降架9固定连接,所述的气泵15对所述的气缸套16进行供气,同时所述的U形管17在所述的气缸套16内上下滑动,所述的升降架9固定连通有进气管18,所述的进气管18和所述的U形管17相连通,所述的U形管17滑动的过程带动所述的升降架9同步滑动;An
所述的U形管17置于所述的气缸套16一端内部固定连接有压力进气阀,所述的压力进气阀包括和所述的U形管17固定连接的外环套管19,所述的外环套管19内部同轴固定连接有进气阀套20,所述的进气阀套20下侧开设有若干通气框21,所述的进气阀套20内部同轴上下滑动连接有升降压力活塞22,所述的升降压力活塞22下端通过弹簧和所述的进气阀套20相连,当所述的升降架9向下滑动至和所述的定位筒3相接触时,所述的U形管17不能滑动,此时对所述的气缸套16持续供气,所述的气压大于所述的升降压力活塞22下方的弹力时,所述的升降压力活塞22向下滑动,将所述的通气框21打开,进而气流通过所述的U形管17内部向所述的升降架9下端流动,在流动过程,使所述的升降活塞筒7和所述的升降架9脱离配合,然后所述的升降活塞筒7在持续气压的作用下,带动所述的切割筒6持续向所述的穿刺针4下端滑动,然后使所述的切割筒6和所述的通孔5配合,便于后续采样;The
本实施例在具体实施时,当需要采样时,首先将所述的穿刺针4连接在所述的定位筒3下端,然后通过对所述的气缸套16进行供气,通过所述的U形管17、升降架9、压力进气阀将所述的切割筒6输送至所述的穿刺针4低端和所述的通孔5配合,然后通过医护人员将转动所述的转动手柄,对患者患处进行穿刺,穿刺完成后,所述的骨髓瘤组织进入所述的切割筒6内,然后启动所述的驱动电机14,所述的驱动电机14转动通过所述的提拉绳11对所述的切割筒6和升降活塞进行提升,同时通过所述的切割筒6实现对骨髓瘤样本组织进行切除,然后将所述的切割筒6提升至所述的送检盒1内,完成整个取样,然后将所述的穿刺针4拆卸清洗,同时通过转运所述的送检盒1,将所述的样本组织直接送至检验区,减少了和外界的接触。In the actual implementation of this embodiment, when sampling is required, the
实施例二,在实施例一的基础上,为了便于对所述的穿刺针4进行拆卸,同时减少对穿刺针4和定位筒3的改造形变,提高对穿刺针4的普适性,故本实施例提供一种对穿刺针4进行有效加持固定的结构,具体的,所述的贯穿孔2下端固定连接有紧固外螺纹套23,所述的穿刺针4贯穿所述的紧固外螺纹套23,所述的紧固外螺纹套23下端径向滑动连接有若干等间距分布的紧固弧形板24,所述的紧固弧形板24下端均开设有弧形轨道25,所述的弧形轨道25内滑动连接有滑动伸缩杆26,所述的滑动伸缩杆26和螺纹连接在所述的紧固外螺纹套23外围的紧固螺母套27固定连接,通过转动所述的紧固螺母套27带动所述的滑动伸缩杆26转动的同时伸缩,然后在所述的滑动伸缩杆26和所述的弧形轨道25配合的作用下,所述的紧固弧形板24沿所述的紧固外螺纹套23进行滑动,进而实现对所述的穿刺针4的限位固定,同时通过所述的紧固螺母套27和所述的紧固外螺纹套23的配合,实现了对所述的紧固弧形板24的锁定,增强了对所述的穿刺针4加持固定的稳定性。
实施例三,在实施例二的基础上,在通过所述的切割筒6对样本组织进行储存时,在后期检测时,需要将样本组织从所述的切割筒6内取出,取用不方便,不能将样本组织直接输送至取样试管37内,故本实施例提供一种取样完成后,直接将样本组织转送至试管内部的结构,具体的,所述的切割筒6内同轴置有载物盘28,所述的载物盘28上端固定连接有铁质环29,所述的载物盘28上固定连接有红外接收器;
所述的切割筒6右侧固定连接有隔板30,所述的隔板30右端转动连接有往复丝杠31,所述的往复丝杠31和转动连接在所述的送检盒1内部的转动套筒32转动连接,所述的往复丝杠31和固定连接在所述的转动套筒32内的取样电机33相连,所述的取样电机33转动带动所述的往复丝杠31同步转动,所述的转动套筒32和固定连接在所述的送检盒1内的支撑圆盘34转动连接,所述的转动套筒32内部固定连接有和所述的往复丝杠31位置对称的限位杆35,所述的限位杆35上左右滑动连接有试管支撑架36,所述的试管支撑架36右端和所述的转动套筒32通过弹簧相连,初始状态,所述的试管支撑架36位于所述的限位杆35的最左端,所述的试管支撑架36上端固定连接有试管限位套,所述的试管限位套内置有取样试管37,所述的往复丝杠31上螺纹连接有和所述的转动套筒32左右滑动连接的取样架38,所述的隔板30上开设有和所述的取样架38相配合的取样窗39,所述的取样架38透过所述的取样窗39伸入所述的切割筒6内部,所述的取样架38下端固定连接有和所述的铁质环29相配合的环形电磁铁,所述的取样架38下端固定连接有和所述的红外接收器相配合的红外发射器,所述的红外接收器和所述的环形电磁铁相连,所述的往复丝杠31转动带动所述的取样架38向所述的切割筒6一侧滑动,所述的取样架38滑动至所述的切割筒6内,然后当和所述的载物盘28和所述的取样架38配合时,所述的红外接收器和红外发射器控制所述的环形电磁铁通电,在所述的环形电磁铁吸力作用,所述的取样架38实现对所述的载物盘28的吸附,同时所述的取样架38向所述的转动套筒32一侧滑动,带动所述的载物盘28同步滑动,滑动至所述的取样架38和所述的试管支撑架36相配合,进而所述的取样架38滑动带动所述的试管支撑架36同步滑动;The right side of the
所述的转动套筒32内部开设有滑行轨道41,所述的滑行轨道41左端固定连通有滑行直轨42,所述的滑行直轨42滑动连接有和所述的取样架38固定连接的滑行销43,所述的取样架38持续滑动带动所述的滑行销43在所述的滑行直轨42和滑行轨道41内滑动,进而在所述的滑行销43和所述的滑行轨道41配合作用下,所述的转动套筒32转动,进而带动所述的支撑圆盘34同步转动,进而实现对所述的试管支撑架36和取样架38的同步转动,进而实现对所述的取样试管37的翻转,同时将样本组织投落至所述的取样试管37内;The inside of the
所述的送检盒1下端固定连接有和所述的试管支撑架36相配合试管加持装置,所述的试管夹持装置为一个弹性夹,使所述的取样试管37翻转后进入所述的弹性夹内部,实现对所述的取样试管37的固定,翻转完成后,所述的取样架38反向滑动,实现对各个部分的复位。The lower end of the inspection box 1 is fixedly connected with a test tube clamping device matched with the test
实施例四,在实施例二的基础上,在通过切割筒6对样本组织进行切割时,所述的切割筒6和所述的通孔5初始为贯通状态,会使外界细菌进入所述的穿刺针4内部,同时在穿刺过程,骨髓瘤组织进入所述的通孔5内的主动性较少,故本实施例提供一种在切割之前对所述的通孔5进行密封的结构,具体的,所述的升降活塞筒7内部上下滑动连接有转动轴杆44,所述的转动轴干上开设有滑动螺纹轨45,所述的升降活塞筒7内部固定连接有和所述的滑动螺纹轨45相配合的滑动销,通过所述的滑动销的上下滑动和所述的滑动螺纹轨45的配合,实现了所述的切割筒6的转动;
所述的转动轴杆44下端和所述的切割筒6固定连接,所述的切割筒6下端轴心处转动连接有转动球46,所述的切割筒6下端一侧固定连接有L形杆47,所述的穿刺针4内部低端开设有和所述的L形杆47相配合的倒L形限位弧形轨48;The lower end of the
所述的定位筒3侧壁固定连接有两个对称分布的弧形限位块49,所述的定位筒3和穿刺针4均开设有和所述的弧形限位块49相配合的弧形限位轨50,通过所述的弧形限位块49和弧形限位轨50的配合实现了所述的升降活塞的上下滑动,并且不会发生自转,同时需要注意的是所述的转动轴杆44上端和所述的升降活塞内壁下端通过磁铁吸附,保证当所述的升降活塞向下滑动时,会带动所述的切割筒6同步滑动,当所述的切割筒6滑动至最下端,所述的L形杆47进入所述的L形限位弧形轨48内部时,所述的升降活塞筒7持续向下滑动,所述的切割筒6发生180度转动,实现对通孔5的密封,同时将需要对骨髓瘤组织进行切割时,所述的升降活塞筒7上升,先带动所述的切割筒6转动至所述的切割筒6和所述的通孔5联通,然后持续提升所述的切割筒6,实现对骨髓瘤组织的切割。The side wall of the
实施例五,在实施例四的基础上,为了保证所述的取样试管37不会在翻转过程脱落,同时顺利进入所述的试管限位套内,故本实施例提供一种新的试管限位套,具体的,所述的试管限位套包括和所述的试管支撑架36固定连接的左半环套51,所述的左半环套51右侧置有和所述的试管支撑架36左右滑动的右半环套52,所述的右半环套52右端固定连接有矩形磁铁53,所述的试管支撑架36右侧上端固定连接有矩形电磁铁54,所述的矩形电磁铁54外界电源,通过所述的矩形电磁铁54的启闭,实现对所述的试管限位套的启闭。
实施例六,在实施例四的基础上,为了保证所述的取样试管37在翻转过程能够顺利进入所述的试管加持装置,同时有效固定,故本实施例提供一种显得试管加持装置,具体的,所述的试管加持装置包括和所述的送检盒1固定连接的承托架55,所述的承托架55上端前后两侧对称置有加持条56,所述的加持条56君合所述的承托架55前后滑动连接,所述的加持条56和所述的承托架55通过弹簧相连,所述的加持条56在所述的承托架55上前后滑动;
所述的加持条56右侧下端均固定连接有滑动推板57,所述的承托架55开设有和所述的滑动推板57相配合的滑行仓58,所述的滑行仓58内均固定连接有伸缩液压杆59,两个所述的伸缩液压杆59和固定连接在所述的承托架55上的进油弯管60通过三通管相连通,所述的进油弯管60后端前后滑动连接有按压活塞杆61,所述的按压活塞杆61后端固定连接有滑动杆62,所述的滑动杆62和前后滑动连接在所述的承托架55上的矩形滑套63固定连接;The lower end of the right side of the
所述的矩形滑套63内上下滑动连接有限位楔形板64,所述的限位楔形板64下端和所述的矩形滑套63通过弹簧相连;The inside of the rectangular sliding
所述的转动套筒32外壁同轴固定连接有驱动环65,所述的驱动环65上固定连接有驱动杆架67,所述的驱动杆架67上转动连接有驱动轮66,所述的转动套筒32转动带动所述的驱动环65转动,所述的驱动环65带动所述的驱动轮66同步转动,所述的驱动轮66转动带动所述的限位楔形板64滑动,所述的限位楔形板64滑动带动所述的按压活塞杆61滑动,所述的按压活塞杆61滑动带动所述的伸缩液压杆59滑动,将所述的加持条56撑开,便于所述的取样试管37进入,所述的加持条56在弹簧的作用下,实现对所述的取样试管37的加持,同时所述的驱动轮66反向转动时,所述的驱动轮66压动所述的限位楔形板64向下滑动,进而所述的矩形滑套63不会发生滑动,实现对取样试管37的有效加持。The outer wall of the
实施例七,在实施例四或五或六的基础上,为了保证送检盒1内的环境,所述的送检盒1内部上端固定连接有若干UV杀菌灯68,所述的送检盒1内固定连接有智能温控器69,通过所述的UV杀菌灯68保证所述的送检盒1内部为无菌环境,同时通过所述的智能温控器69实现对所述的送检盒1内温度的控制。
实施例八,在实施例三或六的基础上,所述的送检盒1上固定连接有控制模块70,所述的控制模块70内部集成有控制单元,所述的红外发射器、红外接收器、驱动电机14、取样电机33、气泵15、环形电磁铁、矩形电磁铁54、UV杀菌灯68和智能温控器69均和所述的控制模块70相连,通过所述的控制模块实现对所述的红外发射器、红外接收器、驱动电机14、取样电机33、气泵15、环形电磁铁、矩形电磁铁54、UV杀菌灯68和智能温控器69的有效统一控制。Embodiment 8, on the basis of
本发明针对现有的骨髓瘤样本采集和送检盒进行改进,通过增设穿刺针、通孔、切割筒、升降活塞筒、磁铁盘、升降架、磁铁环、气泵、U形管、压力进气阀、提拉绳和单向线轮以及驱动电机有效的解决了对患者进行穿刺过程保证骨髓瘤组织能够顺利切除以及在输送过程不至于脱落的问题;通过设置紧固外螺纹套、紧固弧形板、弧形轨道和滑动伸缩杆以及紧固螺母套有效的解决了对穿刺针进行有效固定加持的问题;通过设置载物盘、往复丝杠、转动套筒、取样架、试管支撑架、取样试管、滑行轨道和取样电机有效地解决了对将样本组织置于取样试管内部,以及将取样试管进行翻转收纳的问题;通过设置转动轴杆、滑动螺纹轨、滑动销、L形杆和L形限位弧形轨有效地实现了对切割筒进行转动实现对通孔进行密封和打开,保证骨髓瘤组织更好地进入穿刺针内部的问题;通过设置承托架、加持条、滑动推板、滑行仓和伸缩液压杆有效的解决了对取样试管进行限位加持的问题;通过设置UV杀菌灯和智能温控器有效的解决了对样本进行低温无菌防护的问题;且结构简洁稳定,具有极高的普适性。The present invention improves the existing myeloma sample collection and inspection box by adding a puncture needle, a through hole, a cutting cylinder, a lifting piston cylinder, a magnet plate, a lifting frame, a magnet ring, an air pump, a U-shaped tube, and a pressure intake The valve, the lifting rope, the one-way wire wheel and the driving motor effectively solve the problem of ensuring the smooth resection of the myeloma tissue during the puncture process of the patient and the problem that the myeloma tissue will not fall off during the delivery process; Shaped plate, arc-shaped track, sliding telescopic rod and fastening nut sleeve effectively solve the problem of effectively fixing and supporting the puncture needle; by setting the loading plate, reciprocating screw, rotating sleeve, sampling rack, test tube The sampling test tube, sliding track and sampling motor effectively solve the problem of placing the sample tissue inside the sampling test tube and flipping and storing the sampling test tube; The arc-shaped rail of the shape limit can effectively realize the rotation of the cutting cylinder to seal and open the through hole, so as to ensure that the myeloma tissue can better enter the inside of the puncture needle; , the sliding chamber and the telescopic hydraulic rod effectively solve the problem of limiting the sampling tube; by setting the UV germicidal lamp and the intelligent temperature controller, the problem of low-temperature aseptic protection for the sample is effectively solved; and the structure is simple and stable, It has high universality.
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CN215688324U (en) * | 2021-09-16 | 2022-02-01 | 邱野 | Living body sampling and submitting device for oncology department |
CN114652408A (en) * | 2022-03-22 | 2022-06-24 | 河北省儿童医院 | Paediatrics blood tumour biopsy sample is with supplementary fixing device |
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US4747414A (en) * | 1985-02-20 | 1988-05-31 | Biologie Et Industrie S.A.R.L. | Instrument for bone marrow puncture |
US20020042581A1 (en) * | 1999-03-19 | 2002-04-11 | Cervi Paul Laurence | Biopsy needle |
WO2021243807A1 (en) * | 2020-06-02 | 2021-12-09 | 南京融康博临床医学研究院有限公司 | Tumor sampling device for lung cancer |
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CN114652408A (en) * | 2022-03-22 | 2022-06-24 | 河北省儿童医院 | Paediatrics blood tumour biopsy sample is with supplementary fixing device |
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