CN115337083B

CN115337083B - Medical instrument assembly

Info

Publication number: CN115337083B
Application number: CN202110524195.XA
Authority: CN
Inventors: 赵潺; 夏超然; 孙月广; 李川
Original assignee: Beijing Huashi Novi Medical Technology Co ltd; Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Current assignee: Beijing Huashi Novi Medical Technology Co ltd; Peking Union Medical College Hospital Chinese Academy of Medical Sciences
Priority date: 2021-05-13
Filing date: 2021-05-13
Publication date: 2025-01-10
Anticipated expiration: 2041-05-13
Also published as: CN115337083A

Abstract

The present invention belongs to the field of medical instruments, and discloses a medical instrument assembly, including a medical puncture device, an implant and a hollow auxiliary guide needle. The medical puncture device is configured to be able to push the hollow puncture needle forward to puncture the front closed end of the syringe by pressing a pressing portion and make the injection containing area, the peripheral wall needle hole and the front needle hole connected, and the auxiliary guide needle can be connected to the implant guide structure, so that the implant can be introduced into the needle cavity of the hollow puncture needle through the needle cavity of the auxiliary guide needle and the implant guide structure, thereby realizing the injection, exploration, expansion or instrument implantation of the animal's visible or potential tissue gap, cavity system, and blood vessel, and in particular, realizing the precise control of the puncture depth, stable injection and quantitative injection.

Description

Medical instrument assembly

Technical Field

The invention relates to the technical field of medical appliances, in particular to a medical appliance assembly.

Background

At present, medical instruments can be implanted by means of a conventional injector when treating tissue gaps, lumen systems and vessels of animals in medicine. When in puncture, the puncture depth of the syringe needle needs to be manually controlled, and whether the needle pierces a target area is judged according to the experience of medical staff, but the physiological structures of different patients are generally different, the experience of the medical staff is not necessarily accurate, and thus the puncture accuracy cannot be effectively ensured. When the injector push rod is continuously pressed, if the injection speed is required to be stabilized, the fluid is prevented from being negligent and urgent, and medical staff is required to have a skillful operation method, but in practice, the stability of each injection is difficult to ensure.

Disclosure of Invention

In view of at least one of the above-mentioned drawbacks or shortcomings of the prior art, the present invention provides a medical device assembly that can achieve injection, penetration, dilation or instrument implantation of an apparent or potential tissue space, lumen system, vessel of an animal, and in particular can achieve precise control of penetration depth, stable infusion and quantitative infusion.

In order to achieve the above object, the present invention provides a medical apparatus assembly, including a medical puncturing device, an implant and a hollow auxiliary guide needle, the medical puncturing device includes a syringe, an elastic pushing assembly, a hollow puncturing needle, at least one injection containing area and an implant guiding structure, the syringe includes a front closed end and a rear open end of the syringe, the elastic pushing assembly includes a pressing portion and a movable sealing portion which is located in a syringe cavity and can form a front-back elastic connection with the pressing portion, the hollow puncturing needle is fixedly connected to the pressing portion and forms a front end needle hole and a peripheral wall needle hole, the injection containing area is formed in a syringe cavity area enclosed by the front closed end of the syringe, the peripheral wall of the syringe cavity and the movable sealing portion together;

wherein, medical piercing depth sets up can be through pressing the pressing part in order to with cavity pjncture needle forward pushing to puncture the needle cylinder front dead end and make injection accommodation area perisporium pinhole with front end pinhole intercommunication, supplementary guide needle can with implant guide structure connects, makes the implant can pass through supplementary guide needle's needle chamber with implant guide structure is with the guide into cavity pjncture needle intracavity.

Optionally, the implant guiding structure comprises an inclined guiding groove formed on the movable sealing part and extending obliquely towards the hollow puncture needle, and the auxiliary guiding needle can penetrate into the inner cavity of the syringe from the rear opening end of the syringe and penetrate through the inclined guiding groove to penetrate into the peripheral wall needle hole in front of the movable sealing part.

Optionally, the inclined guide groove is arranged in a penetrating way along the front-back direction, the implant guide structure further comprises a unidirectional valve component which is embedded in the inclined guide groove and can be opened and closed or a guide groove sealing piece which is inserted in the inclined guide groove, and the auxiliary guide needle can prop open the unidirectional valve component forwards or pierce the guide groove sealing piece forwards.

Optionally, the inclined guide groove is formed on the upper surface of the movable sealing part and is a non-through groove, and the auxiliary guide needle can pierce the inclined guide groove forward.

Alternatively, the peripheral wall pin hole is formed as an inclined hole opening toward the obliquely rear, and the front end of the auxiliary guide pin is aligned with the inclined hole when the auxiliary guide pin passes through the inclined guide groove.

Optionally, the implant guiding structure includes an inclined guiding needle hole formed in a peripheral wall of the hollow puncture needle and opening toward an inclined rear direction, the medical puncture device includes a guiding state in which the injection accommodating area, the peripheral wall needle hole and the front end needle hole are communicated, in the guiding state, the inclined guiding needle hole is located at a rear of the movable sealing part, and the auxiliary guiding needle can extend into the syringe cavity from a syringe rear opening end and penetrate into the inclined guiding needle hole.

Optionally, the implant guiding structure further comprises a unidirectional valve component embedded in the inclined guiding pinhole and capable of opening and closing or a pinhole sealing piece inserted in the inclined guiding pinhole, and the auxiliary guiding needle can prop open the unidirectional valve component forwards or pierce the pinhole sealing piece forwards.

Optionally, the implant guiding structure comprises a middle guiding groove formed at the middle position of the rear end face of the pressing part and capable of being pierced, the hollow puncture needle is formed with a rear end needle hole, the rear end needle hole and the middle guiding groove are axially aligned, and the auxiliary guiding needle can pierce the middle guiding groove forwards from the outside of the rear opening end of the needle cylinder and penetrate the rear end needle hole.

Optionally, the implant comprises a filamentous implant, a tubular implant, a needle implant, an electrode, and a sensor.

Optionally, the medical device assembly is configured to enable implantation of the implant into an apparent or potential tissue space, lumen or vessel of an animal.

When the medical apparatus assembly is used, the pressing part in the medical puncturing device is firstly applied with pressure to drive the hollow puncturing needle to puncture the front closed end of the needle cylinder, and when the hollow puncturing needle punctures the apparent or potential tissue gap, cavity system and vessel of an animal and the peripheral wall needle hole is positioned in the injection containing area, the peripheral wall needle hole and the front needle hole are communicated. By reasonable design, the pressure of the injection in the injection containing area can be larger than the pressure in the tissue gap, the cavity system and the vessel, and under the condition of pressure difference, the injection can flow into the displayed or potential tissue gap, the cavity system and the vessel through the peripheral wall needle hole and the front end needle hole in sequence.

In the injection process, the movable sealing part and the pressing part are kept in front-back elastic connection, so that the pressing part is kept pressed without further increasing the pressing force, and the injection can continuously flow into the pinhole of the peripheral wall under the action of the rebound force between the movable sealing part and the pressing part, thereby realizing the injection, penetration and expansion of the obvious or potential tissue gap, cavity system and vessel.

In particular, before the hollow puncture needle pierces the apparent or potential tissue gap, cavity system and vessel, the external pressure applied to the needle hole at the front end is greater than the injection pressure of the injection containing area, so that the injection cannot flow out of the needle hole at the front end, and therefore, whether the hollow puncture needle pierces the apparent or potential tissue gap, cavity system and vessel can be judged by observing whether the movable sealing part moves forwards under the action of the rebound force between the movable sealing part and the pressing part, thereby reminding an operator of the current penetration depth and ensuring the accurate control of the penetration depth. The injection is controlled by the pressure change of the injection containing area, so that the applied thrust is not required to be increased continuously in the injection process, the fluid negligence and emergency can be prevented, and the injection stability is ensured.

After the infusion, the auxiliary guide needle is connected to the implant guiding structure in the medical puncture device, then the implant is led into the needle cavity of the hollow puncture needle through the needle cavity of the auxiliary guide needle and the implant guiding structure, and further extends out from the front needle hole to the tissue gap, the cavity system and the vessel, so that the implantation of the instrument is realized.

Additional features and advantages of the invention will be set forth in the detailed description which follows.

Drawings

The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate the invention and together with the description serve to explain, without limitation, the invention. In the drawings:

FIGS. 1-5 are schematic illustrations of a medical puncturing device in various states of a tissue space, lumen system, vascular puncture and infusion process of an animal in accordance with embodiments of the present invention;

FIGS. 6-10 are schematic views of another medical puncturing device according to an embodiment of the present invention in different states during tissue space, luminal system, vascular puncturing and infusion of an animal;

Fig. 11 to 13 are schematic views showing a partial structure of a medical puncturing device having a plurality of injection containing regions in various states according to an embodiment of the present invention;

fig. 14 to 16 are schematic views showing a partial structure of another medical puncturing device provided with a plurality of injection containing regions in different states according to the embodiment of the present invention;

FIG. 17 is a schematic view of a portion of a medical puncturing device having a through angled guide slot and a one-way valve assembly in accordance with an embodiment of the present invention;

FIG. 18 is a schematic view of a partial construction of a medical device assembly employing the medical puncturing device of FIG. 17;

FIG. 19 is a schematic view showing a partial structure of a medical puncturing device provided with a non-penetrating inclined guide groove in accordance with an embodiment of the present invention;

FIG. 20 is a schematic view of a partial construction of a medical puncturing device provided with an inclined guide needle hole and a one-way valve assembly in accordance with an embodiment of the present invention;

FIG. 21 is a schematic view of a portion of a medical puncturing device provided with an angled guide pinhole and a pinhole seal in accordance with an embodiment of the present invention;

FIG. 22 is a schematic illustration of a medical device assembly with a central guide slot in accordance with an embodiment of the present invention for implantation of an implant into a tissue space, lumen system, vessel of an animal;

Fig. 23-26 are schematic views of another medical puncturing device according to an embodiment of the present invention in different states during tissue space, luminal system, vascular puncturing and infusion of an animal.

Reference numerals illustrate:

1. Needle cylinder 2 pressing part

3. Elastic sheath for movable sealing part 4

5 (5') Spring 6 hollow puncture needle

7. Front end seal of injection containing zone 8

9. Pinhole seal for one-way flapper assembly 10

11. Auxiliary guide needle for implant 12

13. Pressure control slider for isolation seal part 21

1A axial limit part 2c middle guide groove

3A inclined guide groove 6a front end needle hole

6B peripheral wall pinhole 6c inclined guide pinhole

Front injection containing area 7a and rear injection containing area 7b

6B1 front peripheral wall pinhole 6b2 rear peripheral wall pinhole

Detailed Description

The following describes the detailed implementation of the embodiments of the present invention with reference to the drawings. It should be understood that the detailed description and specific examples, while indicating and illustrating the invention, are not intended to limit the invention.

It should be noted that, without conflict, the embodiments of the present invention and features of the embodiments may be combined with each other.

In embodiments of the present invention, the terms "forward, rearward, front end, rear end" and the like are used based on the perspective of an operator (e.g., surgeon, physician, nurse, technician, etc.) using the medical puncturing device or medical instrument assembly of the present invention, i.e., the direction relatively far from the operator is the forward direction and the direction relatively close to the operator is the rearward direction when the operator uses the medical puncturing device or medical instrument assembly.

The invention will be described in detail below with reference to the drawings in connection with exemplary embodiments.

As shown in fig. 1 to 22, a first exemplary embodiment of the present invention provides a medical puncturing device comprising a syringe 1, an elastic pushing assembly, a hollow puncturing needle 6 and at least one injection containing region 7.

The syringe 1 includes a front closed end and a rear open end, and when in production, the syringe 1 can be designed into a structure with two open ends along the axial direction, and the front end opening of the syringe 1 is provided with a front end sealing element 8 to realize sealing, wherein the front end sealing element 8 is made of rubber or other materials which can be punctured by the hollow puncture needle 6.

The elastic pushing component comprises a pressing part 2 and a movable sealing part 3, wherein the movable sealing part 3 is positioned in the inner cavity of the needle cylinder and can axially move, the pressing part 2 is usually at least partially extended out of the rear opening end of the needle cylinder for manual pressing by an operator, the movable sealing part 3 and the pressing part 2 can form front-back elastic connection by applying pressure to the pressing part 2, and at the moment, if the position of the pressing part 2 is kept unchanged, the movable sealing part 3 has a forward moving trend under the action of resilience force between the movable sealing part and the pressing part 2.

Furthermore, the pressing part 2 may also comprise a portion which protrudes into the interior of the needle cylinder and which together with the peripheral wall of the interior of the needle cylinder and the movable sealing part 3 may define a closed area, i.e. the rear of the movable sealing part 3 may be formed with a closed area which may contain a flowing or non-flowing medium, such as a sterilizing gas or the like. Or the part of the pressing part 2 extending into the inner cavity of the syringe can also define a non-closed area together with the peripheral wall of the inner cavity of the syringe and the movable sealing part 3, i.e. the rear part of the movable sealing part 3 can be formed with a non-closed area for connecting with the external environment.

The hollow puncture needle 6 is fixedly connected to the pressing portion 2, and the hollow puncture needle 6 does not move forward to puncture the front closed end of the syringe without applying pressure to the pressing portion 2, but is not limited to a state in which the hollow puncture needle 6 has punctured the front closed end of the syringe when the product leaves the factory. Whereas, for the hollow puncture needle 6 itself, a front end needle hole 6a and a peripheral wall needle hole 6b are formed, the front end needle hole 6a and the peripheral wall needle hole 6b communicate through the needle lumen of the hollow puncture needle 6.

The injection containing area 7 is used for storing injection. Wherein the injections include, but are not limited to, liquids, solutions, suspensions, gels, oils, ointments, emulsions, creams, foams, lotions, pastes, etc., may be stored separately in the injection containing area 7, or may be stored as a mixture. The injection is preferably a liquid (e.g., solution, suspension, etc.) or semi-solid composition (e.g., gel) that is easy to handle, and is preferably capable of shaping after injection and enlargement of the tissue space, lumen system, vessel. For example, the injection may be performed at or near the target site, and the injection may then be coagulated and set, possibly with greater strength to maintain a distended tissue space, lumen, vessel.

Injectables can have fluidity, including formulations having low viscosity, high viscosity, or water-like viscosity, such as pasty materials. The fluidity of the formulation may allow it to conform to irregularities, crevices, cracks and/or interstices at the tissue site. For example, the formulation may be used to fill one or more voids, enlarge tissue voids (e.g., manifest tissue voids) and/or form potential tissue voids into manifest tissue voids, and optionally enlarge the resulting voids. In addition, some injectables can harden upon contact with aqueous media (e.g., body fluids, water, etc.) to form a drug depot that facilitates controlled drug release.

The injection containing area 7 is formed in the area of the cylinder cavity surrounded by the cylinder front closed end, the cylinder cavity peripheral wall and the movable sealing part 3. Since the movable sealing part 3 is axially movable during injection, the injection agent accommodating area 7 has a variable volume, so that the injection agent pressure in the injection agent accommodating area 7 can be changed with the axial movement of the movable sealing part 3.

At the time of puncturing with the medical puncturing device of the present exemplary embodiment, by applying pressure to the pressing portion 2, the hollow puncture needle 6 can be pushed forward to the front closed end of the puncture cylinder, and when the hollow puncture needle 6 punctures the apparent or potential tissue gap, lumen system, vessel and the peripheral wall pinhole 6b is located in the injection containing region 7, the peripheral wall pinhole 6b and the front end pinhole 6a communicate. By reasonable design, the pressure of the injection in the injection containing area 7 can be larger than the pressure in the apparent or potential tissue gap, cavity system and vessel, and under the condition of pressure difference, the injection can flow into the apparent or potential tissue gap, cavity system and vessel through the peripheral wall needle hole 6b and the front end needle hole 6a in sequence.

In the injection process, the movable sealing part 3 and the pressing part 2 are kept in front-back elastic connection, so that the pressing part 2 is kept pressed, the pressing force is not required to be further increased, and the injection can continuously flow into the peripheral wall needle hole 6b under the action of the rebound force between the movable sealing part 3 and the pressing part 2, thereby realizing the injection, penetration and expansion of the obvious or potential tissue gap, lumen system and vessel.

Before the hollow puncture needle 6 penetrates the apparent or potential tissue gap, lumen system, vessel, the external pressure applied at the front needle hole 6a is greater than the injection pressure in the injection containing region 7, so that the injection cannot flow out of the front needle hole 6 a. For example, in the case of the puncturing process of the suprachoroidal space of the eye, when the hollow puncture needle 6 punctures the sclera but does not puncture the suprachoroidal space, the injection does not flow out of the front needle hole 6a regardless of whether the peripheral needle hole 6b communicates with the injection containing region 7, because the sclera is dense, and when the front needle hole 6a is located in the sclera, a large external pressure is formed at the front needle hole 6a, which is larger than the injection pressure in the injection containing region 7, so that the injection cannot flow out.

Therefore, by observing whether the movable sealing part 3 moves forwards under the action of the resilience force between the movable sealing part and the pressing part 2, whether the hollow puncture needle 6 is penetrated into a visible or potential tissue gap, a cavity system or a vessel can be judged, so that the current puncture depth of an operator is reminded, and the accurate control of the puncture depth is ensured. The injection is controlled by the pressure change of the injection in the injection containing area 7, so that the applied thrust is not required to be increased again during the injection process, the injection is prevented from being neglected, and the injection stability is ensured.

In some embodiments, the medical puncturing device further comprises at least one penetrable isolation seal 13 disposed in the region of the barrel interior chamber between the movable seal 3 and the forward, closed end of the barrel and capable of sliding axially. With this structure, the injection containing regions 7 are formed in plurality, and the plurality of injection containing regions 7 are sequentially arranged in isolation in the axial direction by the isolation seal portion 13. The multiple injection containing regions 7 may store the same injection or different injections.

For example, referring to fig. 11 to 16, the injection containing region 7 includes a front injection containing region 7a and a rear injection containing region 7b which are partitioned front and rear.

In the embodiment shown in fig. 11 to 13, the peripheral wall pinhole 6b includes a front peripheral wall pinhole and a rear peripheral wall pinhole that are disposed at intervals in the front-rear direction. With this structure, if the hollow puncture needle 6 is first pierced so that the front peripheral wall needle hole communicates with the front injection accommodating area 7a and the rear peripheral wall needle hole is sealed by the isolation seal 13, the injection in the front injection accommodating area 7a will flow into the apparent or potential tissue gap, lumen system, vessel through the front peripheral wall needle hole and the front end needle hole 6a, the injection dose in the front injection accommodating area 7a is continuously reduced by the resilience force between the movable seal 3 and the pressing part 2, and the movable seal 3 and the isolation seal 13 are continuously moved forward. By reasonable design, before the isolation sealing part 13 blocks the front peripheral wall pinhole, the rear peripheral wall pinhole is communicated with the rear injection containing region 7b, so that the injection in the rear injection containing region 7b flows into the apparent or potential tissue gap, lumen system and vessel through the rear peripheral wall pinhole and the front end pinhole 6a in sequence. Thus, in this embodiment, sequential injection of injectate within the anterior and posterior injectate-containing areas 7a, 7b into the apparent or potential tissue space, lumen system, vasculature may be achieved.

In another embodiment shown in fig. 11 to 13, the hollow puncture needle 6 may be pierced such that the front peripheral wall needle hole communicates with the front injection containing region 7a and the rear peripheral wall needle hole communicates with the rear injection containing region 7b, thereby enabling the injection in the front injection containing region 7a and the rear injection containing region 7b to be mixed and then injected into the apparent or potential tissue space, lumen system, vessel.

In the embodiment shown in fig. 14 to 16, only one peripheral wall needle hole 6b is provided, and by reasonable design, the hollow puncture needle 6 can be pierced such that the front portion of the peripheral wall needle hole 6b communicates with the front injection containing region 7a and the rear portion of the peripheral wall needle hole 6b is sealed by being surrounded by the isolation seal 13. At this time, the injection in the front injection accommodating area 7a flows into the apparent or potential tissue gap, lumen system, and vessel through the front portion of the peripheral wall needle hole 6b and the front end needle hole 6a in this order, the injection dose in the front injection accommodating area 7a is continuously reduced by the elastic force between the movable seal part 3 and the pressing part 2, and the movable seal part 3 and the isolation seal part 13 are continuously moved forward. Also by reasonable design, the rear part of the peripheral wall pinhole 6b can be communicated with the rear injection containing region 7b before the front part of the front peripheral wall pinhole is blocked by the isolating sealing part 13, so that the injection in the rear injection containing region 7b flows into the apparent or potential tissue gap, lumen system and vessel sequentially through the rear part of the peripheral wall pinhole 6b and the front end pinhole 6 a. Thus, in this embodiment, sequential injection of injectate within the anterior and posterior injectate-containing areas 7a, 7b into the apparent or potential tissue space, lumen system, vasculature may also be achieved.

In another embodiment shown in fig. 14 to 16, the hollow puncture needle 6 may be pierced such that the front portion of the peripheral wall needle hole 6b communicates with the front injection containing region 7a, the rear portion of the peripheral wall needle hole 6b communicates with the rear injection containing region 7b, and the portion between the front and rear portions of the peripheral wall needle hole 6b is sealed by being surrounded by the isolation seal 13, whereby the injections in the front injection containing region 7a and the rear injection containing region 7b can be mixed and then injected into the apparent or potential tissue gap, lumen system, vessel.

It should be noted that the explicit or potential tissue gap, lumen system, vessel described herein may be suprachoroidal space, epidural space, pleural space, peritoneal space, articular space, artery, vein, etc., and is not particularly limited, so the medical puncturing device of the present exemplary embodiment also has the advantage of being highly versatile.

The specific position of the hollow puncture needle 6 may slightly differ after shipment and before the medical puncture device of the present exemplary embodiment is used, i.e., the medical puncture device may be set in various shipment configurations.

For example, the hollow spike 6 has pierced the movable seal 3 but has not pierced the forward closed end of the barrel. At this time, the peripheral wall needle hole 6b may be located behind the movable seal portion 3, surrounded and sealed by the movable seal portion 3, or in communication with the injection containing region 7, and the front end needle hole 6a may be in communication with the injection containing region 7 or surrounded and sealed by the front closed end of the cylinder.

Or the hollow spike 6 has pierced the removable seal 3 and the front closed end of the barrel. At this time, the peripheral wall pin hole 6b may be located behind the movable seal portion 3, sealed around by the movable seal portion 3, or in communication with the injection containing region 7, with the front end pin hole 6a being located outside the front closed end of the cylinder.

Or the hollow puncture needle 6 is not penetrated through the movable sealing part 3, namely, is wholly positioned behind the movable sealing part 3. Accordingly, the peripheral wall pinhole 6b and the front end pinhole 6a are located behind the movable seal part 3.

It can be seen that, as long as the peripheral wall needle hole 6b and the injection containing area 7 are not communicated with each other when the product leaves the factory, no matter whether the hollow puncture needle 6 punctures the movable sealing part 3 and the front closed end of the syringe, whether the front end needle hole 6a is positioned outside the front closed end of the syringe or not can avoid the possibility that the injection leaks out from the front end needle hole 6a before puncturing.

In fact, as is clear from the foregoing, if the external pressure to which the distal needle hole 6a is subjected before the communication with the apparent or potential tissue gap, lumen system, and vessel is made larger than the injection pressure in the injection containing region 7 by the reasonable design, the leakage of the injection from the distal needle hole 6a does not occur in advance even if the peripheral needle hole 6b communicates with the injection containing region 7 at the time of product shipment.

Further, there will be a corresponding embodiment as a remedy for the case where the backflow of the injection agent is likely to occur since the peripheral wall pin hole 6b is located behind the movable seal portion 3 and the front end pin hole 6a is located in the injection agent accommodating region 7, and this will not be described in detail herein.

Among different product forms, it is preferable that the hollow puncture needle 6 does not puncture the movable sealing portion 3 when the product leaves the factory, that is, the hollow puncture needle 6 is entirely located behind the movable sealing portion 3. When the medical puncturing device with the delivery form is used for puncturing, the pressing part 2 can be pressed to drive the hollow puncturing needle 6 to sequentially puncture the movable sealing part 3 and the front closed end of the syringe forwards until the front needle hole 6a enters the apparent or potential tissue gap, the cavity system and the vascular, and the peripheral needle hole 6b is communicated with the injection containing region 7.

In order to ensure that the hollow puncture needle 6 can finally puncture the front closed end of the needle cylinder, puncture guiding structures such as a guide groove, a guiding blind hole or a guiding slit for guiding the hollow puncture needle 6 to puncture can be arranged on the rear end surface of the movable sealing part 3.

After the hollow needle 6 pierces the front closed end of the barrel, the medical puncturing device comprises at least two different states, namely a superficial tissue puncturing state and a diversion state.

In the surface tissue puncturing state, the length range of the hollow puncture needle 6 extending from the front closed end of the needle cylinder is the surface tissue puncturing length range, and in the surface tissue puncturing range, the front end of the hollow puncture needle 6 is penetrated into the surface tissue but is not penetrated into the apparent or potential tissue gap, cavity system and vessel, and the external pressure applied to the front end needle hole 6a is larger than the injection pressure in the injection containing region 7 at the moment because the surface tissue is relatively dense, so that the injection cannot flow outwards no matter whether the peripheral wall needle hole 6b is communicated with the injection containing region 7 or not.

In the deflected state, the length of the hollow needle 6 extending from the front closed end of the barrel is in the deflected length range, in which the hollow needle 6 has penetrated into the apparent or potential tissue space, lumen, vessel. As previously mentioned, by proper design, it is ensured that the injection pressure in the injection receiving area 7 is greater than the pressure in the apparent or potential tissue space, lumen system, vessel. When the peripheral wall needle hole 6b communicates with the injection containing region 7, the injection in the injection containing region 7 can flow into the apparent or potential tissue gap, lumen system, vessel through the peripheral wall needle hole 6b and the front end needle hole 6a in sequence in the presence of an internal-external pressure difference.

Various alternative embodiments for controlling the cessation of fluid injection by a medical puncturing device are described below.

In one embodiment, when the medical puncturing device is in the diversion state, the movable sealing part 3 can move forward to block the peripheral wall needle hole 6b under the action of the resilience force between the movable sealing part and the pressing part 2, and the injection liquid is stopped immediately after the peripheral wall needle hole 6b is blocked. It can be seen that the axial position of the circumferential wall needle aperture 6b within the injection-receiving zone 8 defines the maximum injection volume of the medical puncturing device.

For example, when it is desired to empty the injection containing zone 7, the movable seal 3 may be restricted from blocking the peripheral wall pin hole 6b when it moves forward to abut against the front closed end of the barrel, so that the peripheral wall pin hole 6b is located at the front end of the injection containing zone 7. However, in practice, as the injection in the injection containing region 7 gradually flows into the apparent or potential tissue space, lumen system, and vessel, there is a state in which the injection pressure in the injection containing region 7 is the same as the pressure in the apparent or potential tissue space, lumen system, and vessel, and at this time, the movable seal portion 3 is not moved any more due to the balance of the stress. To empty the injectate-containing area 7, the forward thrust exerted on the movable seal 3 is also increased.

For example, referring to the embodiment shown in fig. 6 to 10, a sliding groove (not shown) extending along the axial direction may be provided on the peripheral wall of the syringe 1, and a sliding block (i.e., a portion of the pressing portion 2 extending out of the syringe 1) matching the sliding groove may be provided on the pressing portion 2, so that the upper limit of the pressing movement travel of the pressing portion 2 is greater, when the movable sealing portion 3 is no longer moved due to the balanced stress, a greater pressing force may be applied to the sliding block of the pressing portion 2, so that the pressing portion 2 is driven to move forward, the resilience force between the movable sealing portion 3 and the pressing portion 2 is increased, the stress balance state of the movable sealing portion 3 is broken, and the movable sealing portion 3 is driven to move forward continuously, so that the injection containing region 7 may discharge more fluid, even empty.

Alternatively, the movable seal 3 may be pushed further against the front closed end of the barrel by other actuation arrangements, an alternative actuation arrangement being described in the following embodiments.

In another embodiment, the medical puncturing device comprises a manual control connected to the movable sealing portion 3 and extending partially out of the syringe. For example, the movable sealing portion 3 may be elastically connected to the manual control portion in the front-rear direction, or the manual control portion may be directly and fixedly connected to the movable sealing portion 3, but it is obvious that it is more advantageous to maintain a stable liquid injection speed in the case of elastic connection.

When the injection dose in the apparent or potential tissue gap, cavity system and vessel does not reach the original target, and the movable sealing part 3 is not moved due to the stress balance, the operator can drive the movable sealing part 3 to move forwards continuously by controlling the part of the manual control part extending out of the needle cylinder until the discharged injection dose reaches the original target. With the solution according to this embodiment, the problem of the previous embodiment that the injection containing area 7 cannot be emptied is solved. Of course, the present embodiment is not limited to application in the case where the injection agent accommodation region 7 is to be emptied.

Referring to fig. 23 to 26, a circumferential wall portion of the cylinder 1 located behind the movable seal portion 3 may be provided with a cylinder circumferential wall chute extending in the axial direction, in which case the manual control portion includes a pressurizing control slider 21 slidably engaged with the cylinder circumferential wall chute, the pressurizing control slider 21 extending out of the cylinder 1 through the cylinder circumferential wall chute portion for user operation, and the movable seal portion 3 and the pressurizing control slider 21 are elastically connected in the front-rear direction, for example, a spring 5' as shown in the drawing is provided between the movable seal portion 3 and the pressurizing control slider 21. Under this structure, by further applying pressure to the pressurizing control slider 21 to slide forward along the axial direction of the cylinder peripheral wall chute, the movable seal part 3 and the pressurizing control slider 21 can be elastically compressed, and when the position of the pressurizing control slider is maintained, the movable seal part 3 can break the stress balance state and continue to move forward under the action of the resilience force until the injected dose of the outer row reaches the original target.

In another embodiment, the medical puncturing device may enable quantitative injection of an injection. Specifically, referring to fig. 1 to 10, an axial limiting portion 1a for limiting forward movement of the movable sealing portion 3 is provided in the cylinder inner cavity in front of the movable sealing portion 3, and when the medical puncturing device is in a diversion state, the circumferential wall needle hole 6b is located in front of the axial limiting portion 1a, and the movable sealing portion 3 can move forward under the action of resilience force with the pressing portion 2.

To realize that the movable sealing portion 3 moves to be limited by the axial limiting portion 1a, two cases are divided:

The first condition is that the pressure of the injection in the injection containing area 7 is not less than the pressure in the apparent or potential tissue gap, lumen, vessel until the movable sealing part 3 moves to be limited by the axial limiting part 1a, in other words, the movable sealing part 3 can be pushed forward to be limited by the axial limiting part 1a only by the resilience force between the movable sealing part 3 and the pressing part 2 at this time without any other driving structure.

The second condition is that before the movable sealing part 3 is pushed to abut against the axial limiting part 1a under the action of the resilience force between the movable sealing part 3 and the pressing part 2, the pressure of the injection in the injection containing area 7 is the same as the pressure in the apparent or potential tissue gap, lumen system and vessel (i.e. the movable sealing part 3 is not moved any more due to the stress balance), at this time, the movable sealing part 3 cannot be pushed to be limited by the axial limiting part 1a only by virtue of the resilience force between the movable sealing part 3 and the pressing part 2, so that the movable sealing part 3 needs to be pushed forward further by an additionally arranged driving structure, for example, the driving structure can be the manual control part. In either case, however, the axial stopper 1a provided in the present embodiment is the basis for achieving quantitative injection of the injection.

The following describes various different puncture and injection timings of the medical puncture device.

In one embodiment, before the hollow puncture needle 6 extends out from the front closed end of the needle cylinder, the peripheral wall needle hole 6b is always kept above the injection containing area 7, so that the phenomenon of early leakage of liquid at the front end needle hole 6a can be avoided, and the reliability of the medical puncture device can be improved.

In another embodiment, the peripheral wall needle aperture 6b at least partially communicates with the injectate holding area 7 when the medical puncturing device is in a superficial tissue puncturing state, i.e., when the length of the hollow spike 6 extending from the forward closed end of the barrel is within the superficial tissue puncturing length (or when the forward end of the hollow spike 6 is penetrating into superficial tissue but not yet penetrating into the apparent or potential tissue gap, lumen system, vessel). In other words, before the front end of the hollow puncture needle 6 is pierced into the apparent or potential tissue gap, lumen system, vessel, the injection agent containing region 7, the peripheral wall needle hole 6b and the front end needle hole 6a are brought into communication in advance, so that the injection agent is injected into the needle cavity of the hollow puncture needle 6 in advance, at least a part of the air is discharged, and the amount of air entering the apparent or potential tissue gap, lumen system, vessel is reduced.

More preferably, the peripheral wall needle hole 6b is communicated with the injection agent accommodating area 7 at the same time when the front end of the hollow puncture needle 6 starts to puncture the surface tissue, so that when the front end of the hollow puncture needle 6 is punctured into the apparent or potential tissue gap, cavity system or vessel, the needle cavity of the hollow puncture needle 6 is already filled with the injection agent, and the possibility of air entering the apparent or potential tissue gap, cavity system or vessel is completely stopped.

In another embodiment, when the medical puncturing device is in a deflected state, i.e., when the length of the hollow puncturing needle 6 extending from the forward closed end of the syringe is within the deflected length range (or when the forward end of the hollow puncturing needle 6 is penetrated into the apparent or potential tissue gap, lumen system, vessel), the peripheral wall needle aperture 6b is already fully positioned within the injectate holding area 7 such that the flow rate of the peripheral wall needle aperture 6b is maximized, thereby enhancing the injection speed.

The above three embodiments may be implemented either alone or in combination.

An embodiment in which reverse overflow from the peripheral wall needle hole 6b by reverse flow of the fluid is prevented will be described.

When the front needle hole 6a is in communication with the injection containing area 7 while the peripheral needle hole 6b is still located behind the movable sealing portion 3, or when the front needle hole 6a is located in a visible or potential tissue gap, lumen, vessel while the peripheral needle hole 6b is still located behind the movable sealing portion 3, there is a risk that the injection flows back and overflows reversely from the peripheral needle hole 6 b. Therefore, the elastic sheath 4 sleeved outside the hollow puncture needle 6 can be arranged in the elastic pushing component, and when the peripheral wall needle hole 6b is positioned behind the movable sealing part 3 (namely, when the peripheral wall needle hole 6b is not communicated with the injection containing area 7), the elastic sheath 4 can keep to seal the peripheral wall needle hole 6b, so that backflow and overflow of the injection can be effectively avoided, the rear area of the movable sealing part 3 can be prevented from being polluted, the fluid loss can be reduced, and the reliability of the product can be improved.

In fact, the elastic sheath 4 can be used only as an elastic connection member between the movable seal portion 3 and the pressing portion 2 even if it is not used to seal the peripheral wall pin hole 6 b. Specifically, by pressing the pressing portion 2 forward, the elastic sheath 4 between the movable seal portion 3 and the pressing portion 2 is pressed, thereby forming a repulsive force between the movable seal portion 3 and the pressing portion 2, driving the movable seal portion 3 to move forward. The elastic connection member between the movable seal portion 3 and the pressing portion 2 may be a spring 5 whose both ends in the axial direction are connected to the movable seal portion 3 and the pressing portion 2, respectively. The spring 5 and the elastic sheath 4 may be provided separately or in combination.

The elastic connection between the movable sealing part 3 and the pressing part 2 may be achieved by other means than the provision of an elastic connection member. For example, the movable seal portion 3 and the pressing portion 2 may be provided as an integrally molded elastic member.

Various embodiments of the ability to implant medical devices into the apparent or potential tissue space, lumen system, vasculature, etc. through a medical puncturing device are described below, for ease of understanding, the implanted medical device is exemplified by a wire-like or tubular implant 11, although the implant 11 could alternatively be a needle-like implant, electrode, sensor, etc.

Specifically, the medical puncturing device is provided with an implant guiding structure for guiding the implant 11 into the needle cavity of the hollow puncture needle 6.

In one embodiment, referring to fig. 17 to 19, the implant guiding structure includes an inclined guide groove 3a formed on the movable sealing part 3 and extending obliquely toward the hollow puncture needle 6. When the injectate holding area 7, the peripheral wall needle hole 6b and the front end needle hole 6a are communicated, the injectate is first to be injected into the apparent or potential tissue gap, lumen system, vessel expansion, and then the implant 11 is implanted into the expanded apparent or potential tissue gap, lumen system, vessel through the inclined guide groove 3a, the peripheral wall needle hole 6b, the needle cavity of the hollow puncture needle 6 and the front end needle hole 6 a.

The inclined guide groove 3a may be a through groove penetrating in the front-rear direction or a non-through groove formed on the upper surface of the movable seal portion 3.

When the inclined guide groove 3a is a through groove, the implant guide structure may further include a one-way valve assembly 9 which is embedded in the inclined guide groove 3a and can be opened and closed, and the one-way valve assembly 9 is in a normally closed state when no external force is applied, so that the injection in the injection containing area 7 is prevented from leaking from the one-way valve assembly, but when an opening force is applied, a plurality of valves of the implant guide structure can be opened, so that the implant 11 can penetrate from an opening to the peripheral wall needle hole 6b. Alternatively, the implant guiding structure may comprise a guiding groove seal inserted into the inclined guiding groove 3a, and the guiding groove seal may be pulled out when the implant 11 is required to be implanted.

When the inclined guide groove 3a is a non-penetrating groove, the implant 11 can be directly penetrated by the implant 11 or the implant 11 can be penetrated through the penetrating opening to penetrate the peripheral wall needle hole 6b after being penetrated by other penetrating members.

In this embodiment, to match the guiding of the inclined guide groove 3a, the peripheral wall pinhole 6b may be provided as an inclined hole opening obliquely rearward, so that the peripheral wall pinhole 6b can be aligned with the inclined guide groove 3a to accurately introduce the implant 11.

In another embodiment, referring to fig. 20 and 21, the implant guiding structure comprises an inclined guiding needle hole 6c formed in the circumferential wall of the hollow puncture needle 6 and opening obliquely rearward, the inclined guiding needle hole 6c also being always maintained behind the movable sealing part 3 in the guiding state of the medical puncturing device, through which inclined guiding needle hole 6c the implant 11 can be threaded into the needle cavity of the hollow puncture needle 6 and implanted through the front needle hole 6a into the dilated apparent or potential tissue gap, lumen system, vessel.

Similar to the previous embodiment, the implant guiding structure may further comprise a unidirectional valve assembly 9 inserted into the inclined guide needle hole 6c and capable of opening and closing, or a needle hole sealing member 10 inserted into the inclined guide needle hole 6c, and the implantation operation of the implant 11 may be performed by opening the unidirectional valve assembly 9 or pulling out the needle hole sealing member 10.

In another embodiment, referring to fig. 22, the implant guiding structure includes a center guide groove 2c formed at a center position of a rear end surface of the pressing part 2 and pierceable, the hollow puncture needle 6 is formed with a rear end needle hole, and the rear end needle hole is disposed in axial alignment with the center guide groove 2 c. When the implant 11 is needed to be implanted, the middle guide groove 2c can be pierced first, then the implant 11 is penetrated into the needle cavity of the hollow puncture needle 6 through the piercing opening of the middle guide groove 2c and the rear end needle hole of the hollow puncture needle 6, and then the expanded and obvious or potential tissue gap, cavity system and vessel can be further implanted through the front end needle hole 6 a.

Several embodiments of medical puncturing devices formed in a split structure are described below.

In one embodiment, a medical puncturing device includes a puncturing control module and a fluid storage module formed separately from one another. Wherein, the puncture control module comprises a first syringe unit, an elastic pushing component and a hollow puncture needle 6 which are arranged in the cylinder cavity of the first syringe unit, and the puncture control module can also comprise an elastic sheath 4, a spring 5 and other components as can be known in combination with the different embodiments. And the fluid storage module includes a second syringe unit, an injection solution accommodating zone 7 formed in a barrel cavity of the second syringe unit, and a module housing detachably mounted at a rear end of the second syringe unit. A detachable connection structure is formed between the first needle cylinder unit and the second needle cylinder unit, and the first needle cylinder unit and the second needle cylinder unit are spliced with each other to form the needle cylinder 1. It will be appreciated that in connection with the various embodiments described above, the fluid storage module may also include a front end seal 8 or the like.

Therefore, the puncture control module and the fluid storage module can be respectively produced and assembled into the medical puncture device. The module package is used for sealing the rear end of the injection containing area 7, and can be disassembled when the puncture control module and the fluid storage module are assembled.

In another embodiment, a medical puncturing device includes a puncturing control module and a fluid storage module formed separately from one another. Wherein, the puncture control module comprises a first syringe unit, a pressing part 2 and a hollow puncture needle 6 which are arranged in the cylinder cavity of the first syringe unit, and the puncture control module can also comprise an elastic sheath 4, a spring 5 and other components as can be known in combination with the different embodiments. And the fluid storage module includes a second cylinder unit, an injection containing zone 7 formed in a cylinder chamber of the second cylinder unit, and a movable sealing part 3 enclosed at a rear end of the second cylinder unit, the movable sealing part 3 being adapted to seal a rear end of the injection containing zone 7. A detachable connection structure is formed between the first needle cylinder unit and the second needle cylinder unit, the first needle cylinder unit and the second needle cylinder unit are spliced with each other to form a needle cylinder 1, and the movable sealing part 3 and the pressing part 2 are elastically connected front and back. It will be appreciated that in connection with the various embodiments described above, the fluid storage module may also include a front end seal 8 or the like.

In another embodiment, a medical puncturing device includes a puncturing control module, a transitional coupling module, and a fluid storage module formed independently of one another. Wherein, the puncture control module comprises a first syringe unit, a pressing part 2 and a hollow puncture needle 6 which are arranged in the cylinder cavity of the first syringe unit, and the puncture control module can also comprise an elastic sheath 4, a spring 5 and other components as can be known in combination with the different embodiments. The transitional coupling module comprises a second syringe unit and a movable sealing part 3 arranged in the cylinder cavity of the second syringe unit. The fluid storage module comprises a third needle unit, an injectate-containing area 7 formed in the barrel cavity of the third needle unit, and a module package removably packaged at the rear end of the third needle unit. The first needle cylinder unit, the second needle cylinder unit and the third needle cylinder unit are sequentially and detachably connected, the first needle cylinder unit, the second needle cylinder unit and the third needle cylinder unit are sequentially spliced to form the needle cylinder 1, and the movable sealing part 3 and the pressing part 2 are elastically connected front and back. It will be appreciated that in connection with the various embodiments described above, the fluid storage module may also include a front end seal 8 or the like.

A second exemplary embodiment of the present invention provides a medical device assembly, referring to fig. 18 and 22, comprising an implant 11 and a medical puncturing device as described above with implant guiding structures, whereby the implant 11 can be implanted through the medical puncturing device into an apparent or potential tissue space, lumen system, vessel (including but not limited to suprachoroidal space, epidural space, pleural space, peritoneal cavity, joint cavity, artery, vein) of an animal. In addition, the medical device assembly in the present exemplary embodiment obviously has all the technical effects brought by the above-described medical puncturing device, so that the detailed description is not repeated here.

In one embodiment, the medical device assembly further includes a hollow auxiliary guide needle 12 adapted for use with the implant guiding structure, the auxiliary guide needle 12 having a needle cavity aperture of sufficient size for penetration of the implant 11. When the implantation operation of the implant 11 is performed, the auxiliary guide needle 12 is connected with the implant guide structure, so that the implant 11 can sequentially pass through the needle cavity of the auxiliary guide needle 12 and the implant guide structure to be guided into the needle cavity of the hollow puncture needle 6, and then the obvious or potential tissue gap, cavity system and vessel are implanted through the front needle hole 6 a.

For example, referring to fig. 18, the implant guiding structure includes a through inclined guide groove 3a and a one-way flap assembly 9 fitted into the inclined guide groove 3a and openable, and the peripheral wall needle hole 6b is provided as an inclined hole opening obliquely rearward. When the implant 11 is implanted, the auxiliary guide needle 12 is used to open the unidirectional valve component 9 so as to be penetrated in the inclined guide groove 3a, the front end of the auxiliary guide needle 12 penetrates into the peripheral wall needle hole 6b, and then the implant 11 is sequentially implanted into the apparent or potential tissue gap, cavity system and vessel through the needle cavity of the auxiliary guide needle 12, the needle cavity of the hollow puncture needle 6 and the front end needle hole 6 a.

In another embodiment, the implant guiding structure includes an inclined guide groove 3a penetrating in the front-rear direction and a guide groove seal inserted into the inclined guide groove 3a, and the auxiliary guide needle 12 can pierce the guide groove seal forward and the front end penetrates the peripheral wall needle hole 6b to communicate with the needle cavity of the hollow puncture needle 6.

In another embodiment, an inclined guide groove 3a is formed on the upper surface of the movable sealing portion 3 and is a non-penetrating groove, and the auxiliary guide needle 12 can pierce the inclined guide groove 3a forward and the front end penetrates the peripheral wall needle hole 6b so as to communicate with the needle cavity of the hollow piercing needle 6.

The peripheral wall pin hole 6b in the above-described embodiment may be formed as an inclined hole opening obliquely rearward so that the front end of the auxiliary guide pin 12 can be aligned with the inclined hole when the auxiliary guide pin 12 passes through the inclined guide groove 3 a.

In another embodiment, the implant guiding structure comprises an inclined guiding pin hole 6c formed in the circumferential wall of the hollow puncture needle 6 and opening obliquely rearward, the inclined guiding pin hole 6c being located behind the movable sealing part 3 in the guiding state of the medical puncturing device, and the auxiliary guiding pin 12 being capable of extending into the lumen of the needle cylinder from the rear open end of the needle cylinder and penetrating into the inclined guiding pin hole 6c, thereby communicating with the needle lumen of the hollow puncture needle 6.

Further, the implant guiding structure may further comprise a one-way valve assembly 9 inserted into the inclined guiding pinhole 6c and openable or a pinhole seal 10 inserted into the inclined guiding pinhole 6c, so that the auxiliary guiding needle 12 can prop open the one-way valve assembly 9 forward or puncture the pinhole seal 10 forward, thereby communicating with the needle cavity of the hollow puncture needle 6.

Alternatively, referring to fig. 22, the implant guiding structure includes a central guide groove 2c, and the hollow puncture needle 6 is formed with a rear end needle hole disposed in axial alignment with the central guide groove 2 c. When the implant 11 is implanted, the auxiliary guide needle 12 is firstly utilized to puncture the middle guide groove 2c, so that the auxiliary guide needle 12 is axially positioned at the rear end needle hole of the hollow puncture needle 6, then the implant 11 sequentially penetrates into the needle cavity of the hollow puncture needle 6 through the needle cavity of the auxiliary guide needle 12 and the rear end needle hole of the hollow puncture needle 6, and further is implanted into the apparent or potential tissue gap, cavity system and vessel through the front end needle hole 6 a.

The foregoing details of the optional implementation of the embodiment of the present invention have been described in conjunction with the accompanying drawings, but the embodiment of the present invention is not limited to the specific details of the foregoing implementation, and various simple modifications may be made to the technical solution of the embodiment of the present invention within the scope of the technical concept of the embodiment of the present invention, where all the simple modifications belong to the protection scope of the embodiment of the present invention.

In addition, the specific features described in the foregoing embodiments may be combined in any suitable manner, and in order to avoid unnecessary repetition, various possible combinations are not described further.

In addition, any combination of various embodiments of the present invention may be performed, so long as the concept of the embodiments of the present invention is not violated, and the disclosure of the embodiments of the present invention should also be considered.

Claims

1. The medical apparatus assembly is characterized by comprising a medical puncturing device, an implant (11) and a hollow auxiliary guide needle (12), wherein the medical puncturing device comprises a needle cylinder (1), an elastic pushing assembly, a hollow puncturing needle (6), at least one injection containing area (7) and an implant guide structure, the needle cylinder (1) comprises a needle cylinder front closed end and a needle cylinder rear open end, the elastic pushing assembly comprises a pressing part (2) and a movable sealing part (3) which is positioned in a needle cylinder inner cavity and can form front-back elastic connection with the pressing part (2), the hollow puncturing needle (6) is fixedly connected with the pressing part (2) and is provided with a front end needle hole (6 a) and a peripheral wall needle hole (6 b), and the injection containing area (7) is formed in a needle cylinder inner cavity area surrounded by the needle cylinder front closed end, the needle cylinder inner cavity peripheral wall and the movable sealing part (3);

Wherein, medical piercing depth sets up can be through pressing press portion (2) in order to with cavity pjncture needle (6) forward push to puncture before the cylinder blind end makes injection holding area (7) perisporium pinhole (6 b) with front end pinhole (6 a) intercommunication, supplementary guide needle (12) can with implant guide structure connection, make implant (11) can pass through the needle chamber of supplementary guide needle (12) with implant guide structure is with the guide to the guide into the needle intracavity of cavity pjncture needle (6).

2. The medical device assembly according to claim 1, wherein the implant guiding structure comprises an inclined guiding groove (3 a) formed on the movable sealing part (3) and extending obliquely towards the hollow puncture needle (6), the auxiliary guiding needle (12) being able to penetrate into the syringe lumen from the syringe rear opening end and through the inclined guiding groove (3 a) to penetrate into the peripheral wall needle hole (6 b) located in front of the movable sealing part (3).

3. The medical device assembly according to claim 2, wherein the inclined guide groove (3 a) is provided through in the front-rear direction, the implant guide structure further comprises a one-way valve assembly (9) which is embedded in the inclined guide groove (3 a) and can be opened and closed or a guide groove sealing member which is inserted in the inclined guide groove (3 a), and the auxiliary guide needle (12) can prop open the one-way valve assembly (9) forward or puncture the guide groove sealing member forward.

4. Medical device assembly according to claim 2, wherein the inclined guide groove (3 a) is formed on the upper surface of the movable sealing part (3) and is a non-penetrating groove, and the auxiliary guide needle (12) is capable of piercing the inclined guide groove (3 a) forward.

5. The medical instrument assembly according to claim 2, wherein the peripheral wall pinhole (6 b) is formed as an inclined hole opening obliquely rearward, and a front end of the auxiliary guide needle (12) is aligned with the inclined hole when the auxiliary guide needle (12) passes through the inclined guide groove (3 a).

6. The medical device assembly according to claim 1, wherein the implant guiding structure comprises an inclined guiding needle hole (6 c) formed in a peripheral wall of the hollow puncture needle (6) and opening obliquely rearward, the medical puncturing device comprising a guiding state in which the injection agent accommodating area (7), the peripheral wall needle hole (6 b) and the front end needle hole (6 a) are in communication, in which guiding state the inclined guiding needle hole (6 c) is located rearward of the movable sealing part (3), and the auxiliary guiding needle (12) is capable of extending into the syringe lumen from the syringe rear opening end and penetrating into the inclined guiding needle hole (6 c).

7. The medical device assembly according to claim 6, wherein the implant guiding structure further comprises a one-way flap assembly (9) embedded in the inclined guiding needle hole (6 c) and openable or a needle hole seal (10) inserted in the inclined guiding needle hole (6 c), the auxiliary guiding needle (12) being capable of spreading the one-way flap assembly (9) forward or piercing the needle hole seal (10) forward.

8. The medical device assembly according to claim 1, wherein the implant guiding structure comprises a puncturable middle guiding groove (2 c) formed at a middle position of a rear end face of the pressing portion (2), the hollow puncture needle (6) is formed with a rear end needle hole, the rear end needle hole and the middle guiding groove (2 c) are axially aligned, and the auxiliary guiding needle (12) can puncture the middle guiding groove (2 c) from outside a rear opening end of the syringe and penetrate into the rear end needle hole.

9. The medical device assembly according to claim 1, wherein the implant (11) comprises a wire implant, a tubular implant, a needle implant, an electrode and a sensor.

10. The medical device assembly according to any one of claims 1 to 9, wherein the medical device assembly is arranged to enable implantation of the implant (11) in a apparent or potential tissue space, lumen or vessel of an animal.