CN114734497A - A biological tissue slicer - Google Patents
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- 238000005520 cutting process Methods 0.000 abstract description 3
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/0006—Means for guiding the cutter
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/26—Means for mounting or adjusting the cutting member; Means for adjusting the stroke of the cutting member
- B26D7/2614—Means for mounting the cutting member
- B26D7/2621—Means for mounting the cutting member for circular cutters
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B26—HAND CUTTING TOOLS; CUTTING; SEVERING
- B26D—CUTTING; DETAILS COMMON TO MACHINES FOR PERFORATING, PUNCHING, CUTTING-OUT, STAMPING-OUT OR SEVERING
- B26D7/00—Details of apparatus for cutting, cutting-out, stamping-out, punching, perforating, or severing by means other than cutting
- B26D7/26—Means for mounting or adjusting the cutting member; Means for adjusting the stroke of the cutting member
- B26D7/2628—Means for adjusting the position of the cutting member
- B26D7/2635—Means for adjusting the position of the cutting member for circular cutters
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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Abstract
Description
技术领域technical field
本发明涉及实验设备领域,具体为一种生物组织切片机。The invention relates to the field of experimental equipment, in particular to a biological tissue slicer.
背景技术Background technique
现有的生物组织切片机是采用的人工刀切方式进行组织切片,切片不仅用于观察正常细胞组织的形态结构,也是病理学和法医学等学科用以研究、观察及判断细胞组织的形态变化的主要方法,而且也已相当广泛地用于其他许多学科领域的研究中。The existing biological tissue slicer adopts the artificial knife cutting method to make tissue slices. Slices are not only used to observe the morphological structure of normal cell tissue, but also used in pathology and forensic science to study, observe and judge the morphological changes of cell tissue. The main method, and has also been used quite widely in research in many other disciplines.
但是现有的生物组织切片机大多数是采用的人工操作,效率慢工作时间长。而采用机械化切片的机器大多数是实现切片功能,切片完全后再进行切片的转移和压实完成切片的整个组装。整个流程的厚度不均匀,且切片组装时间长,不利于工业化生产。However, most of the existing biological tissue slicers are manually operated, and the efficiency is slow and the working time is long. Most of the machines that use mechanized slicing are to realize the slicing function. After the slicing is completed, the transfer and compaction of the slicing are performed to complete the entire assembly of the slicing. The thickness of the whole process is not uniform, and the slice assembly time is long, which is not conducive to industrial production.
发明内容SUMMARY OF THE INVENTION
本发明为了解决现有技术中存在的缺陷,提供一种切片厚度一致,并且切片速度快的生物组织切片机。In order to solve the defects existing in the prior art, the present invention provides a biological tissue slicer with uniform slice thickness and fast slice speed.
本发明首先提供一种生物组织切片机,包括切片箱、设置在切片箱内的推片装置、设置在推片装置前端的切片盘、侧面推动切片盘水平向滑动的第一推杆、设置在切片盘另一侧的转动承接板;所述切片盘设置成上切片盘和下切片盘,上切片盘顶部连接一第二推杆,下切片盘设置于切片箱滑槽内;上切片盘经第二推杆竖直向升降与下切片盘实现分合,上切片盘和下切片盘组合成的切片盘经第一推杆推动在切片箱滑槽内滑动到转动承接板中完成切片和转移。The present invention first provides a biological tissue slicer, comprising a slice box, a slice pusher arranged in the slicer box, a slicer disc arranged at the front end of the slicer device, a first push rod for laterally pushing the slicer to slide horizontally, and The rotating receiving plate on the other side of the slicing plate; the slicing plate is arranged into an upper slicing plate and a lower slicing plate, a second push rod is connected to the top of the upper slicing plate, and the lower slicing plate is arranged in the chute of the slicing box; The second push rod vertically moves up and down to realize opening and closing with the lower slicing tray. The slicing tray formed by the upper slicing tray and the lower slicing tray is pushed by the first push rod and slides into the rotating receiving plate in the chute of the slicing box to complete the slicing and transfer. .
本发明还提供如下优化方案:The present invention also provides the following optimization scheme:
优选的,所述上切片盘顶部设置有上切片盘滑槽。Preferably, the top of the upper slicing tray is provided with an upper slicing tray chute.
优选的,所述第二推杆底部设置有第二推杆滑块与上切片盘滑槽适配。Preferably, the bottom of the second push rod is provided with a second push rod sliding block to fit with the upper slicing tray chute.
优选的,所述下切片盘侧面设置有下切片盘侧面孔。Preferably, the side surface of the lower slicing disc is provided with a side hole of the lower slicing disc.
优选的,所述第一推杆前端设置有第一推杆卡合块与下切片盘侧面孔适配。Preferably, the front end of the first push rod is provided with a first push rod engaging block to fit with the side hole of the lower slicing plate.
优选的,所述转动承接板设置有转动承接板滑槽承接下切片盘。Preferably, the rotating receiving plate is provided with a sliding groove of the rotating receiving plate to receive the lower slicing plate.
优选的,所述转动承接板中线底部设置有转动装置。Preferably, a rotating device is provided at the bottom of the center line of the rotating receiving plate.
优选的,所述推片装置包括尾部的第三推杆、连接第三推杆前端的置物腔。Preferably, the pusher device includes a third push rod at the tail and a storage cavity connected to the front end of the third push rod.
优选的,所述置物腔设置成圆形。Preferably, the storage cavity is arranged in a circular shape.
优选的,所述置物腔顶部设置有置物腔开口。Preferably, the top of the storage cavity is provided with an opening of the storage cavity.
本发明的有益效果是:The beneficial effects of the present invention are:
1、本发明的生物组织切片机能进行单片切片的直接切割和组装,切割的同时完成组装,快速高效;1. The biological tissue slicer of the present invention can directly cut and assemble a single slice, and complete the assembly while cutting, which is fast and efficient;
2、本发明的生物组织切片机整个流程都是机械化操作,操作精度高,切片厚度一致;2. The entire process of the biological tissue slicer of the present invention is a mechanized operation, with high operation precision and consistent slice thickness;
3、本发明的生物组织切片机切片厚度可调,将上切片盘的切片厚度进行调整就可以进行切片厚度的调整;3. The slice thickness of the biological tissue slicer of the present invention is adjustable, and the slice thickness can be adjusted by adjusting the slice thickness of the upper slice plate;
4、本发明的生物组织切片机整个切片过程中是在密封空间内进行切片工作,污染少。4. During the whole slicing process of the biological tissue slicer of the present invention, the slicing work is performed in a sealed space, and the pollution is less.
附图说明Description of drawings
图1为本发明的生物组织切片机的第一立体图;Fig. 1 is the first perspective view of the biological tissue slicer of the present invention;
图2为本发明的生物组织切片机的第二立体图;2 is a second perspective view of the biological tissue slicer of the present invention;
图3为本发明的生物组织切片机的第一立体透视图;3 is a first perspective perspective view of the biological tissue slicer of the present invention;
图4为本发明的生物组织切片机的第二立体透视图;4 is a second perspective view of the biological tissue slicer of the present invention;
图5为本发明的生物组织切片机的透视侧视图;5 is a perspective side view of the biological tissue slicer of the present invention;
图6为本发明的生物组织切片机的第一内部立体图;6 is a first internal perspective view of the biological tissue slicer of the present invention;
图7为本发明的生物组织切片机的第二内部立体图;7 is a second internal perspective view of the biological tissue slicer of the present invention;
具体的附图标记为:The specific reference signs are:
1切片箱;2推片装置;3切片盘;4第一推杆;5转动承接板;6第二推杆;11切片箱滑槽;12切片箱上切片盘进口;13切片箱下切片盘进口;14切片盘出口;21第三推杆;22置物腔;31上切片盘;32下切片盘;33连接槽;34连接卡块;41第一推杆卡合块;51转动承接板滑槽;52转动装置;53转动承接板中间卡合块;61第二推杆滑块;221置物腔开口;311上切片盘滑槽;312上切片盘切刀;313上切片盘弧形部;314上切片盘连接块;321下切片盘侧面孔;322下切片盘挡板;323下切片盘弧形部;324下切片盘连接块。1 Slicing box; 2 Pushing device; 3 Slicing plate; 4 First push rod; 5 Rotating receiving plate; 6 Second push rod; 11 Slicing box chute; Inlet; 14 Slicing tray outlet; 21 Third push rod; 22 Storage cavity; 31 Upper slicing tray; 32 Lower slicing tray; 33 Connecting groove; 34 Connecting block; 52 Rotating device; 53 Rotating the middle engaging block of the receiving plate; 61 Second push rod slider; 221 Storage cavity opening; 311 Upper slicing tray chute; 312 Upper slicing tray cutter; 313 Upper slicing tray arc; 314 upper slicing disc connecting block; 321 lower slicing disc side hole; 322 lower slicing disc baffle; 323 lower slicing disc arc part; 324 lower slicing disc connecting block.
具体实施方式Detailed ways
为了使本领域的技术人员更好地理解发明的技术方案,下面结合具体实施方式对本发明作进一步的详细说明。In order to make those skilled in the art better understand the technical solution of the invention, the present invention will be further described in detail below with reference to the specific embodiments.
如图1-7所示,本发明首先提供一种生物组织切片机,包括切片箱1、设置在切片箱1内的推片装置2、设置在推片装置2前端的切片盘3、侧面推动切片盘3水平向滑动的第一推杆4、设置在切片盘3另一侧的转动承接板5;所述切片盘3设置成上切片盘31和下切片盘32,上切片盘31顶部连接一第二推杆6,下切片盘32设置于切片箱滑槽11内;上切片盘31经第二推杆6竖直向升降与下切片盘32实现分合,上切片盘31和下切片盘32组合成的切片盘3经第一推杆4推动在切片箱滑槽11内滑动到转动承接板5中完成切片和转移。As shown in Figures 1-7, the present invention first provides a biological tissue slicer, comprising a
如图1和2所示,所述切片箱1优选的设置成方形箱,并且更优选的设置成长方形箱。所述切片箱1侧面设置有切片箱上切片盘进口12、切片箱下切片盘进口13、切片盘出口14。切片箱上切片盘进口12优选的设置在第一推杆4一侧,切片箱下切片盘进口13也优选的设置在第一推杆4一侧。如图6和7所示,推片装置2用于推动组织片的水平向位移。切片盘3设置成上切片盘31和下切片盘32,上切片盘31在背面设置有上切片盘切刀312,上切片盘31整体设置有上切片盘弧形部313,两侧设置上切片盘连接块314。下切片盘32在前端设置有下切片盘挡板322,下切片盘32整体设置有下切片盘弧形部323,两侧设置下切片盘连接块324。所述上切片盘连接块314和下切片盘连接块324适配,并且其中上切片盘连接块314或下切片盘连接块324的相接面上设置有连接槽33,另一个上设置有连接卡块34,这样设置来进行上切片盘31和下切片盘32的固定连接。并且优选的上切片盘切刀312设置成圆形,并且优选的只是在弧形的下半圆的外侧设置有环形的切刀,其余内侧部分设置成透明材质,优选的为玻璃材质。下切片盘挡板322优选的设置成透明材质,优选的为玻璃材质。上切片盘31中间的上切片盘弧形部313优选的设置成上半圆形,下切片盘弧形部323优选的设置成下半圆形。上切片盘切刀312、下切片盘挡板322、上切片盘弧形部313和下切片盘弧形部323围合成一完整的组织切片。As shown in Figures 1 and 2, the
如图3和4所示,为了与第二推杆6连接,所述上切片盘31顶部设置有上切片盘滑槽311。切片箱上切片盘进口12顶部设置成倒T型,用于和上切片盘滑槽311配合滑动稳定卡合上切片盘31。As shown in FIGS. 3 and 4 , in order to connect with the
所述第二推杆6底部设置有第二推杆滑块61与上切片盘滑槽311适配。第二推杆滑块61能直接与上切片盘滑槽311适配,在上切片盘31的水平向位移时能产生相对位移,而在竖直向上固定上切片盘31。A second
为了能与第一推杆4稳定连接,所述下切片盘32侧面设置有下切片盘侧面孔321。所述下切片盘侧面孔321可以设置成圆形孔,也可以设置成长方形孔或者其他不规则孔形。所述第一推杆4前端设置有第一推杆卡合块41与下切片盘侧面孔321适配。所述第一推杆卡合块41设置成圆形或者长方形,并且与下切片盘侧面孔321的孔形适配。In order to be stably connected with the
所述转动承接板5设置有转动承接板滑槽51承接下切片盘32。转动承接板滑槽51的高度优选的设置成与切片箱滑槽11的高度一致。转动承接板滑槽51优选的在中间设置有转动承接板中间卡合块53,转动承接板中间卡合块53与下切片盘侧面孔321的孔形一致,能卡合进下切片盘32的侧面。The
所述转动承接板5中线底部设置有转动装置52。所述转动装置52优选的为旋转电机。所述转动装置52以转动承接板5的中心点为转动圆心。转动承接板5可以设置成以旋转电机为圆心点,以半径方向圆周向设置多个转动承接板滑槽51,优选的设置两个以上,更优选的设置两个、四个、八个。A
所述推片装置2包括尾部的第三推杆21、连接第三推杆21前端的置物腔22。所述推片装置2包括尾部的第三推杆21,第三推杆21前端设置有置物腔22,第三推杆21的前端部分在置物腔22内水平向位移,并推动设置在置物腔22内的组织片沿置物腔22的轴向位移。第三推杆21的推动方向与第一推杆4的推动方向优选在同一水平线,并且相互间夹角呈90度。所述置物腔22设置成圆形。所述置物腔22顶部设置有置物腔开口221。所述置物腔开口221优选的设置在置物腔22的顶部,并且优选的设置成以置物腔22的直径为开口宽度以方便组织片能直接放入置物腔22内。The
切片箱1优选的在两侧设置有切片箱上切片盘进口12、切片箱下切片盘进口13、切片盘出口14。切片箱上切片盘进口12与上切片盘31的大小一致,切片箱下切片盘进口13与下切片盘32的大小一致,切片盘出口14与上切片盘31和下切片盘32组合成的完整的切片盘3大小一致。切片箱1的正面优选的设置有切片箱1开口用于组织片的放入和取出,优选的切片箱1的正面设置成透明。The
实施例Example
如图1-7所示,本实施例的生物组织切片机,包括切片箱1、设置在切片箱1内的推片装置2、设置在推片装置2前端的切片盘3、侧面推动切片盘3水平向滑动的第一推杆4、设置在切片盘3另一侧的转动承接板5;所述切片盘3设置成上切片盘31和下切片盘32,上切片盘31顶部连接一第二推杆6,下切片盘32设置于切片箱滑槽11内;上切片盘31经第二推杆6竖直向升降与下切片盘32实现分合,上切片盘31和下切片盘32组合成的切片盘3经第一推杆4推动在切片箱滑槽11内滑动到转动承接板5中完成切片和转移。所述上切片盘31顶部设置有上切片盘滑槽311。所述第二推杆6底部设置有第二推杆滑块61与上切片盘滑槽311适配。所述下切片盘32侧面设置有下切片盘侧面孔321。所述第一推杆4前端设置有第一推杆卡合块41与下切片盘侧面孔321适配。所述转动承接板5设置有转动承接板滑槽51承接下切片盘32。所述转动承接板5中线底部设置有转动装置52。所述推片装置2包括尾部的第三推杆21、连接第三推杆21前端的置物腔22。所述置物腔22设置成圆形。所述置物腔22顶部设置有置物腔开口221。As shown in FIGS. 1-7 , the biological tissue slicer of this embodiment includes a
本实施例的生物组织切片机的使用方法为:The use method of the biological tissue slicer of the present embodiment is:
将组织片从切片箱1开口伸入切片箱1,并从置物腔开口221放置于置物腔22内,设置在第三推杆21的前端并关闭置物腔开口221。然后将上切片盘31从切片箱上切片盘进口12卡合好,水平横向推入切片箱1,启动第二推杆6竖直向收缩到与切片箱上切片盘进口12适配的位置,使上切片盘31的上切片盘滑槽311与第二推杆滑块61横向插入并完成插合。同样的,将下切片盘32的下切片盘侧面孔321与第一推杆4的第一推杆卡合块41插合后,启动第一推杆4将下切片盘32从切片箱下切片盘进口13推入切片箱滑槽11。一直到下切片盘32停止在置物腔22的前端位置后,停止第一推杆4。然后启动第三推杆21将组织片推动到下切片盘挡板322并与其完全贴合后,启动第二推杆6竖直向带动上切片盘31从组织片的正上方位置下切,缓慢切割组织片成组织切片,并在这个过程中,连接槽33与连接卡块34逐渐接近并最终插合后完成组织切片的装片过程,然后启动第一推杆4将切片盘3整个从切片盘出口14推出,整个过程中第二推杆6与上切片盘31横向逐渐分离开,完成脱离。然后切片盘3从切片箱滑槽11内滑动到转动承接板5内,下切片盘侧面孔321与转动承接板中间卡合块53插合,然后启动转动装置52进行转动承接板5的转动并将新的转动承接板滑槽51转动到与切片盘出口14对应的位置完成切片盘3的转移。The tissue piece is inserted from the opening of the
综上所述,首先在整个过程中,整个切片盘3的位移平稳,整个过程中切片的厚度的把握精准,不存在太多的切片的转动和位移,整个流程中只有上切片盘31的水平和竖直向的位移,并且在多个角度上都设置有位移限定偏转的装置,使得整个过程中上切片盘31不会有转动和偏移,下切片盘32也通过切片箱滑槽11进行位移的限定,这样首先能确保最终的切片盘3内的组织切片完整并且厚度均匀,并且减少整个流程中可能存在的卡死和位移不流畅的可能性,整个过程中将上切片盘31和下切片盘32的位移偏转可能性减少到了最低,整个流程的废片极少,适合流水线生产。To sum up, first of all, in the whole process, the displacement of the
以上仅是本发明的优选实施方式,应当指出的是,上述优选实施方式不应视为对本发明的限制,本发明的保护范围应当以权利要求所限定的范围为准。对于本技术领域的普通技术人员来说,在不脱离本发明的精神和范围内,还可以做出若干改进和润饰,这些改进和润饰也应视为本发明的保护范围。The above are only the preferred embodiments of the present invention. It should be noted that the above preferred embodiments should not be regarded as limitations of the present invention, and the protection scope of the present invention should be based on the scope defined by the claims. For those skilled in the art, without departing from the spirit and scope of the present invention, several improvements and modifications can also be made, and these improvements and modifications should also be regarded as the protection scope of the present invention.
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