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CN114450589A - 分析血液样本中红细胞方法及血液分析系统 - Google Patents

分析血液样本中红细胞方法及血液分析系统 Download PDF

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Publication number
CN114450589A
CN114450589A CN201980100664.6A CN201980100664A CN114450589A CN 114450589 A CN114450589 A CN 114450589A CN 201980100664 A CN201980100664 A CN 201980100664A CN 114450589 A CN114450589 A CN 114450589A
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suspension
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sample
red blood
volume distribution
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叶波
祁欢
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood

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Abstract

分析血液样本中红细胞的方法及血液分析系统(100)。该方法包括：从该血液样本获取第一试样，使该第一试样与第一反应试剂混合得到第一混悬液，该第一混悬液中，红细胞基本维持原有形态；从该血液样本获取第二试样，使该第二试样与含有溶血剂的第二反应试剂混合得到第二混悬液，该第二混悬液中，红细胞被裂解；检测该第一混悬液，获得逐个细胞的第一电信号，并根据该第一电信号获得细胞的第一体积分布信息；检测该第二混悬液，获得逐个细胞的光学信息，通过该光学信息识别白细胞，至少根据该白细胞的前向散射光信息获得白细胞的第二体积分布信息，或者检测该第二混悬液，获得逐个细胞的第二电信号，并根据该第二电信号获得白细胞的第三体积分布信息；用该第二体积分布信息或该第三体积分布信息校正该第一体积分布信息，获得该血液样本中红细胞的校正体积分布信息。

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PCT国内申请，说明书已公开。

Claims (30)

  1. PCT国内申请，权利要求书已公开。
CN201980100664.6A 2019-10-23 2019-10-23 分析血液样本中红细胞方法及血液分析系统 Pending CN114450589A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116067934A (zh) * 2023-03-28 2023-05-05 赛默飞世尔（上海）仪器有限公司 用于信号采集的方法和设备

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114729871A (zh) * 2021-08-05 2022-07-08 深圳迈瑞动物医疗科技有限公司 一种样本分析装置、动物用分析装置和样本分析方法
CN113777009B (zh) * 2021-08-31 2024-04-16 深圳迈瑞动物医疗科技股份有限公司 适用于绵羊、山羊和奶牛的细胞分析仪及细胞检测方法
CN114813522B (zh) * 2022-06-29 2022-10-21 深圳安侣医学科技有限公司 基于显微放大数字图像的血液细胞分析方法及系统

Citations (1)

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WO2007024661A2 (en) * 2005-08-24 2007-03-01 Beckman Coulter, Inc. Precise measurement of red blood cells in a blood sample

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US6410330B1 (en) * 2001-07-27 2002-06-25 Coulter International Corp. Method for measurement of nucleated red blood cells
WO2005076995A2 (en) * 2004-02-10 2005-08-25 Beckman Coulter, Inc. Method of measurement of nucleated red blood cells
US7822276B2 (en) * 2005-02-17 2010-10-26 Iris International, Inc. Method and apparatus for analyzing body fluids
JP4926812B2 (ja) * 2007-02-01 2012-05-09 シスメックス株式会社 血球分析装置および体液分析方法
EP3382035B1 (en) * 2011-12-27 2021-08-11 Abbott Laboratories Cellular analysis of body fluids
CN104515728B (zh) * 2013-09-30 2019-07-23 深圳迈瑞生物医疗电子股份有限公司 血液细胞分析仪及网织红细胞计数装置和计数修正方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007024661A2 (en) * 2005-08-24 2007-03-01 Beckman Coulter, Inc. Precise measurement of red blood cells in a blood sample

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116067934A (zh) * 2023-03-28 2023-05-05 赛默飞世尔（上海）仪器有限公司 用于信号采集的方法和设备

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