CN114305359B - Blood pressure data acquisition equipment and chip - Google Patents

Abstract

The embodiment of the application relates to the technical field of blood pressure measurement, and provides blood pressure data acquisition equipment and a chip. The blood pressure data acquisition device is used for measuring the blood pressure value of an object to be measured, and comprises: acquiring a plurality of pressure values applied to the object to be detected and blood vessel volume variation corresponding to the plurality of pressure values respectively, and enabling the duration of the plurality of pressure values applied to the object to be detected to respectively maintain preset maintaining duration; and obtaining the blood pressure value of the object to be measured according to the pressure values and the blood vessel volume variation corresponding to the pressure values. The embodiment of the application can solve the influence caused by the hysteresis phenomenon of the blood vessel and improve the accuracy of the blood pressure measurement value.

Description

Blood pressure data acquisition equipment and chip

Technical Field

The embodiment of the application relates to the technical field of blood pressure measurement, in particular to blood pressure data acquisition equipment and a chip.

Background

With the improvement of living standard, more and more people begin to pay more attention to their health condition. The blood pressure is an important physiological health index, and can reflect the health state of the human body to a certain extent. For example, hypertension increases the risk of renal failure, blindness, and other diseases. Hypertension is also often accompanied by the appearance of other risk factors, such as obesity, diabetes, and high cholesterol, further increasing health risks. Therefore, daily blood pressure monitoring is of great importance to people.

In practice, however, since the vessel wall is a viscoelastic body, there is a hysteresis in the strain of the vessel, and thus there may be a hysteresis in the data acquired during the blood pressure measurement, resulting in inaccurate blood pressure values to be finally measured.

Disclosure of Invention

The embodiment of the application aims to provide blood pressure data acquisition equipment and a blood pressure data acquisition chip, so as to reduce the influence caused by the hysteresis phenomenon of blood vessels and improve the accuracy of blood pressure value measurement results.

In a first aspect, an embodiment of the present application provides a blood pressure data collection device for measuring a blood pressure value of a subject to be measured, including: acquiring a plurality of pressure values applied to the object to be detected and blood vessel volume variation corresponding to the plurality of pressure values respectively, and enabling the duration of the plurality of pressure values applied to the object to be detected to respectively maintain preset maintaining duration; and obtaining the blood pressure value of the object to be measured according to the pressure values and the vascular volume variation corresponding to the pressure values.

As a possible embodiment, the number of pressure values is distributed uniformly in the preset pressure interval based on a preset pressure interval.

As a possible implementation manner, the acquiring a plurality of pressure values applied to the object to be measured and vascular volume variation amounts corresponding to the plurality of pressure values respectively further includes: if the pressure values and the blood vessel volume change amounts respectively corresponding to the pressure values uniformly distributed in the preset pressure interval do not meet the preset requirement, estimating a key pressure interval and a non-key pressure interval for calculating the blood pressure value of the object to be measured according to the pressure values uniformly distributed in the preset pressure interval and the blood vessel volume change amounts respectively corresponding to the pressure values; selecting a plurality of first pressure values in the key pressure interval, and selecting a plurality of second pressure values in the non-key pressure interval; wherein the first pressure values are densely distributed in the critical pressure interval, and the second pressure values are sparsely distributed in the non-critical pressure interval; the first pressure values and the second pressure values applied to the object to be detected are obtained, and the blood vessel volume variation corresponding to the first pressure values and the blood vessel volume variation corresponding to the second pressure values are obtained.

As a possible embodiment, the number of pressure values is non-uniformly distributed in the preset pressure interval based on morphological features of a preset ideal envelope curve.

As a possible implementation manner, the morphological characteristics of the preset ideal envelope curve include critical positions and non-critical positions; the plurality of pressure values are densely distributed at the key positions and sparsely distributed at the non-key positions.

As a possible implementation manner, the starting point and the ending point of the preset pressure interval are respectively an envelope starting point pressure and an envelope ending point pressure corresponding to a preset ideal envelope curve; the ideal envelope curve is used to calculate a blood pressure value.

As a possible implementation manner, the value range of the holding time period is as follows: 1 s-6 s.

As a possible implementation manner, the value range of the holding time period is as follows: 2 s-6 s.

As a possible embodiment, the holding time period is 3s.

As one possible implementation, the order in which the number of pressure values are applied is sequenced or non-sequenced; the sequencing includes: increasing or decreasing.

As a possible implementation manner, in a case where the order in which the plurality of pressure values are applied is non-sequential, the obtaining the blood pressure value of the object to be measured according to the plurality of pressure values and the blood vessel volume variation amounts corresponding to the plurality of pressure values respectively includes: sorting the plurality of pressure values in ascending or descending order; and obtaining the blood pressure value of the object to be measured according to the sequenced pressure values and the blood vessel volume variation corresponding to the pressure values.

As a possible implementation manner, before the obtaining the vascular volume variation corresponding to the plurality of pressure values, the method further includes: displaying a pressing prompt message through an interactive interface, wherein the pressing prompt message comprises: the pressure value to be applied in the current holding time period, the pressure value to be applied in the next holding time period or the holding time period corresponding to each applied pressure value.

In a second aspect, an embodiment of the present application provides a chip, where the chip is connected to a memory, and the memory stores instructions executable by the chip, where the instructions are executed by the chip, so that the chip can perform the blood pressure acquisition method according to the first aspect or any of the optional manners of the first aspect.

In a third aspect, an embodiment of the present application provides an electronic device, including: the chip of the second aspect, and a memory connected to the chip.

In a fourth aspect, an embodiment of the present application provides a computer readable storage medium storing a computer program, where the computer program is executed by a processor to implement the blood pressure acquisition method according to the first aspect or any one of the alternatives of the first aspect.

Compared with the prior art, the method and the device for measuring the blood vessel volume change of the application acquire a plurality of pressure values applied to the object to be measured and vascular volume change corresponding to the plurality of pressure values respectively; the time length for which the pressure value is applied is kept for a preset keeping time length which is longer than or equal to the time length required for eliminating the influence of the vascular hysteresis effect; and obtaining the blood pressure value of the object to be measured according to the blood vessel volume variation corresponding to the pressure values and the pressure values. By setting a certain holding time for the applied pressure value, the influence of the vascular hysteresis effect is eliminated, so that the data required for measuring the blood pressure are acquired more accurately, and the accuracy of the blood pressure value measurement result is improved.

Drawings

One or more embodiments are illustrated by way of example and not limitation in the figures of the accompanying drawings, in which like references indicate similar elements, and in which the figures of the drawings are not to be taken in a limiting sense, unless otherwise indicated.

FIG. 1 is a schematic diagram of the variation of cuff pressure P with time t provided by an embodiment of the present application;

FIG. 2 is a schematic diagram showing the variation of the pressure pulse wave in the cuff according to the variation of the pressure P in the cuff according to the embodiment of the present application;

FIG. 3 is a schematic diagram of calculating a blood pressure value by using a double Gaussian fitting method according to an embodiment of the application;

fig. 4 is a schematic structural diagram of a blood pressure data acquisition module for actively pressing a finger according to an embodiment of the present application;

fig. 5 is a schematic structural diagram of an air bag type blood pressure data acquisition module provided by an embodiment of the application;

fig. 6 is a schematic flow chart of a blood pressure acquisition method according to an embodiment of the present application;

FIG. 7 is a schematic illustration of an ideal envelope curve provided by an embodiment of the present application;

FIG. 8 is a schematic diagram of a uniform distribution of several pressure values provided by an embodiment of the present application;

FIG. 9 is a schematic diagram of a uniform stepwise variation of pressure values provided by an embodiment of the present application;

FIG. 10 is a schematic illustration of a non-uniform distribution of several pressure values provided by an embodiment of the present application;

FIG. 11 is a schematic illustration of a non-uniform piecewise variation in pressure values provided by an embodiment of the present application;

FIG. 12 is a flow chart of one implementation of step 301 provided by an embodiment of the present application;

FIG. 13 is a schematic diagram of a sequence of several pressure values from small to large in the acquisition process according to an embodiment of the present application;

FIG. 14 is a schematic diagram showing the order of the pressure values from large to small in the acquisition process according to the embodiment of the present application;

FIG. 15 is a schematic diagram showing the order of several pressure values in a non-sequenced acquisition process provided by an embodiment of the present application;

fig. 16 is a schematic structural diagram of an electronic device according to an embodiment of the present application.

Detailed Description

For the purpose of making the objects, technical solutions and advantages of the embodiments of the present application more apparent, the following detailed description of the embodiments of the present application will be given with reference to the accompanying drawings. However, those of ordinary skill in the art will understand that in various embodiments of the present application, numerous technical details have been set forth in order to provide a better understanding of the present application. However, the claimed application may be practiced without these specific details and with various changes and modifications based on the following embodiments. The following embodiments are divided for convenience of description, and should not be construed as limiting the specific implementation of the present application, and the embodiments can be mutually combined and referred to without contradiction.

Current blood pressure measurement tools in common use include: mercury sphygmomanometers based on korotkoff sounds, electronic sphygmomanometers based on oscillography or pulse wave methods, and the like. The blood pressure measurement scheme based on oscillography or pulse wave method needs to collect the fluctuation of arterial blood vessel volume of the measurement part (arm, finger, etc.) under the action of external force to calculate systolic pressure, diastolic pressure and mean arterial pressure, namely, needs a user to actively apply pressure to the measurement part to obtain the fluctuation of the blood vessel volume along with the external force under the action of external force. For example, the user manually increases the pressure at which the finger presses the pressure sensor (i.e., the pressure applied to the measurement site), while measuring the finger PPG signal by a photo-pulse wave (PPG) sensor to reflect the change of the blood vessel volume with the external force. The wall penetrating pressure, the mean arterial pressure and the external force have the following relation: transmural pressure = mean arterial pressure-external force.

Taking a traditional cuff oscillometric sphygmomanometer as an example, a schematic diagram of the change of the cuff pressure P with time t is shown in fig. 1, a blood vessel volume change is indicated by the pressure pulse wave in the cuff, and a schematic diagram of the change of the pressure pulse wave in the cuff with the cuff pressure P is shown in fig. 2. From the pressure-vessel volume change envelope to the blood pressure prediction, the general calculation method is as follows: the corresponding pressure at the change of the blood vessel volume is the average arterial pressure, and then the internal relation among the systolic pressure, the diastolic pressure and the average arterial pressure is determined according to the envelope characteristic, and finally the blood pressure value is obtained.

FIG. 3 is a schematic diagram of calculating blood pressure values using a double Gaussian fitting method. Referring to fig. 3, the method of calculating the blood pressure value is as follows

First, an envelope curve is fitted by a double gaussian function:

wherein A1 and B1 are respectively the ordinate and the abscissa of the peak point of the envelope curve, A2 is the ordinate of the intersection point of the envelope curve and the y axis, B2 is the difference between the abscissa of the peak point and the point which is positioned at the left side of the peak point and is half of the height of the peak point on the envelope curve, and B3 is the difference between the abscissa of the peak point and the point which is positioned at the right side of the peak point and is half of the height of the peak point on the envelope curve.

Then, after parameters of the envelope curve are obtained, the diastolic pressure (Diastole pressure, DBP), systolic pressure (systolic blood pressure, SBP) and mean arterial pressure (mean blood pressure, MBP) are calculated from the following formulas:

SBP＝2.5*MBP-1.6*DBP

From the principle of oscillography or pulse wave method, it is known that whether an accurate envelope curve can be obtained is one of the key factors that can accurately and stably measure blood pressure values, and whether an accurate envelope curve can be obtained depends on whether an accurate pressure value and its corresponding blood vessel volume variation can be acquired. However, the applicant found that, since the vessel wall is a viscoelastic body, there is a hysteresis in the strain of the vessel, so that there is a problem of hysteresis in the pressure value collected during the blood pressure measurement and the volume change amount of the vessel corresponding thereto, and thus the obtained envelope curve is deformed, which eventually causes an increase in the blood pressure measurement error.

In the actual collection process, the change of the blood vessel volume under the action of a certain external force can be accurately collected, and the blood pressure measurement accuracy is particularly important. In order to solve the technical problem that the obtained data may have hysteresis due to the hysteresis phenomenon of the strain of the blood vessel and thus inaccurate blood pressure measured values, the embodiment of the application provides a blood pressure acquisition method which is applied to electronic equipment, wherein the electronic equipment comprises a blood pressure data acquisition module, and a structural schematic diagram of the blood pressure data acquisition module can refer to fig. 4 or 5. Fig. 4 is a blood pressure data acquisition module for actively pressing a finger, including: cover plate 101, PPG sensor 102, pressure sensor 103, support structure 104 between cover plate 101 and pressure sensor 103. The PPG sensor 102 includes a light-emitting Diode (LED) 1021 and a Photodiode (PD) 1022. Fig. 5 is a schematic diagram of an air bag type blood pressure data acquisition module, including: a finger cuff balloon 201, a pressure sensor 202, a PPG sensor 203, and a gas tubing (gas tubing) 204. Wherein PPG sensor 203 comprises LED 2031 and PD 2032.

The flow chart of the blood pressure acquisition method provided by the embodiment of the application can refer to fig. 6, which comprises the following steps:

step 301: the method comprises the steps of obtaining a plurality of pressure values applied to an object to be detected and vascular volume variation corresponding to the plurality of pressure values respectively, and enabling the duration of the plurality of pressure values applied to the object to be detected to be kept for a preset keeping duration respectively.

The hold time period is greater than or equal to the time period required to eliminate the effects of the vascular hysteresis effect. The vascular hysteresis effect can be understood as: hysteresis in the strain of the vessel to external forces. The object to be measured is a user needing to measure blood pressure, the obtaining of the plurality of pressure values applied by the object to be measured can be the obtaining of the plurality of pressure values applied by the measuring part of the object to be measured, and the measuring part can be an arm, a finger and the like of the object to be measured.

In one example, the hold time is greater than or equal to 1s, which is advantageous to minimize the effects of vascular hysteresis in different measurement objects.

In one example, the duration of the hold for the different pressure values may be the same or different, e.g., if it is detected that valid data has not been collected while a certain pressure value is applied, the duration of the hold for the pressure value may be increased appropriately. In a specific implementation, if the effective data corresponding to the pressure value is collected under the action of the applied pressure value, the object to be tested can be prompted to change the applied pressure value, and the object to be tested is prompted to apply the pressure value, so that the holding time length can be adaptively changed based on whether the effective data is collected or not.

In an example, for a blood pressure data acquisition module that is actively pushed by a user, for example, referring to fig. 4, the obtaining a plurality of pressure values applied to an object to be measured may be: the user actively presses the measurement part with different pressing forces through the fingers to form a plurality of pressure values, and the plurality of pressure values can be acquired by the pressure sensor in the blood pressure data acquisition module. The blood vessel volume change corresponding to each pressure value can be obtained through pressure pulse waves acquired by a pressure pulse sensor in the blood pressure data acquisition module, or through photoelectric volume pulse waves acquired by a PPG sensor in the blood pressure data acquisition module. The object to be tested can apply a plurality of different pressure values with different pressing forces under the instruction of the electronic equipment, and each applied pressure value is kept for a certain time, so that each pressure value collected by the pressure sensor can be kept for a preset keeping time, the continuous change of the pressure value applied by the object to be tested is avoided, and the influence of a vascular hysteresis effect is eliminated.

In one example, for the cuff/balloon type blood pressure data acquisition module, the balloon type blood pressure data acquisition module may refer to fig. 5, and the acquisition of a plurality of pressure values applied to the object to be measured may be: in the process of acquiring inflation pressurization and deflation depressurization of the cuff/air bag, a plurality of pressure values with different sizes of an object to be tested are formed due to pressure change, and the plurality of pressure values can be acquired by the pressure sensors in the blood pressure data acquisition module. The blood vessel volume change amount corresponding to each pressure value can be obtained by collecting the pressure pulse wave in the cuff/air bag in the process of inflation/deflation (namely pressure change), and can also be obtained by collecting the photoelectric volume pulse wave PPG in the cuff/air bag in the process of pressure change, that is, the change of the pressure pulse wave and the photoelectric volume pulse wave can reflect the change of the blood vessel volume. The cuff/air bag type blood pressure data acquisition module can control the inflation/deflation suspension in the cuff/air bag to keep the air pressure in the cuff/air bag unchanged, and keep a certain keeping time for the time of the inflation/deflation suspension, so that a preset keeping time for the applied pressure value can be kept, the continuous change of the pressure value applied to the measuring part of the object to be measured is avoided, and the influence of the vascular hysteresis effect is eliminated.

Step 302: obtaining a blood pressure value of an object to be measured according to the plurality of pressure values and the blood vessel volume variation corresponding to the plurality of pressure values respectively;

wherein, one pressure value corresponds to one blood vessel volume variation, the blood vessel volume variation corresponding to different pressure values can reflect the fluctuation variation of the blood vessel volume under the action of different pressures, and the blood pressure value of the object to be measured can be calculated through the fluctuation variation of the blood vessel volume; the calculated blood pressure value of the subject may include: systolic pressure, diastolic pressure, mean arterial pressure. Specifically, an envelope curve may be fitted according to the vascular volume variation corresponding to different pressure values, and the blood pressure value may be calculated by using the fitted envelope curve, for example, a double gaussian fitting method as shown in fig. 3 may be used to calculate the blood pressure value.

In one example, the electronic device comprises a chip and a blood pressure data acquisition module connected with the chip, the blood pressure data acquisition module sends a plurality of acquired pressure values and blood vessel volume variation corresponding to the pressure values to the chip, and the blood pressure values are calculated by the chip according to the pressure values and the blood vessel volume variation corresponding to the pressure values.

In this embodiment, by setting a certain holding time period for the applied pressure value, the influence caused by the vascular hysteresis effect is advantageously eliminated, so that the data required for calculating the blood pressure value is more accurately collected, and the accuracy of measuring the blood pressure value is improved.

In one embodiment, the holding duration of each pressure value is used for balancing the duration required for eliminating the influence of the vascular hysteresis effect and the operation duration required for obtaining the blood pressure value, so that the long operation duration required for obtaining the blood pressure value is avoided while the influence of the vascular hysteresis effect is eliminated, for example, the pressing duration of the object to be tested on the test part is not too long, and the measurement experience of the object to be tested is improved.

In one embodiment, the value range of the hold time period is: 1 s-6 s. I.e. the holding time period may be greater than or equal to 1s and less than or equal to 6s, i.e. the holding time period does not exceed 6s at maximum, avoiding the long operation time period required for obtaining the blood pressure value.

In one embodiment, the value range of the hold time period is: 2 s-6 s. I.e., the holding time period may be greater than or equal to 2s and less than or equal to 6s. The method is beneficial to improving the accuracy of the blood pressure value measurement result and simultaneously enabling the user to keep good experience.

In one embodiment, the duration of the hold is 3s, the effect of vascular hysteresis can be substantially completely eliminated, and the duration of the operation required to obtain the blood pressure value is not too long.

In one embodiment, the step 301 further includes: and displaying a pressing prompt message through the interactive interface, wherein the pressing prompt message is used for prompting the pressure value to be applied in the current holding time period of the object to be tested, the pressure value to be applied in the next holding time period or the holding time period corresponding to each applied pressure value.

For example, the electronic device may have a display screen on which one or more of the above-mentioned pressing prompt messages may be displayed, or one or more of the above-mentioned pressing prompt messages may be played in a voice form, so that the object to be tested may clearly know the magnitude of the pressure value that needs to be applied currently, the magnitude of the pressure value that needs to be applied next, or the holding time period that needs to be corresponding to each pressure value.

In the embodiment of the application, it is considered that the existing linear pressure detection scheme often needs a user to slowly increase or decrease the external force applied to the pressure sensor, otherwise, the detected PPG signal fluctuation is too large, and finally, the blood pressure measurement result is inaccurate; in addition, if the detection process is to be accelerated by reducing the amount of sample data, important sample point data is easily lacking or a complete envelope curve cannot be obtained, so that the blood pressure measurement result is inaccurate. According to the embodiment of the application, a user does not need to slowly operate, only the user needs to sequentially maintain the applied pressure values of all the sizes according to the prompt of the interactive interface, and a complete envelope curve for calculating the blood pressure value can be obtained, so that the measurement of the blood pressure value of the user is completed quickly and accurately.

In one embodiment, the plurality of pressure values mentioned in step 301 are uniformly distributed in the preset pressure interval based on the preset pressure interval; the starting point and the ending point of the preset pressure interval are envelope starting point pressure and envelope ending point pressure corresponding to a preset ideal envelope curve respectively, and the ideal envelope curve is used for calculating a blood pressure value. When a plurality of pressure values uniformly distributed in a preset pressure interval are arranged according to the sequence of the sizes, the pressure difference value between any two adjacent pressure values is equal, namely the pressure intervals are equal.

A schematic diagram of an ideal envelope curve can be understood as referring to fig. 7, which is an envelope curve for calculating a blood pressure value obtained by fitting from a pressure value and a blood vessel volume change amount acquired under an ideal environment. In this embodiment, finger data of some reference users may be collected in advance in an ideal environment, an envelope curve corresponding to each reference user and used for calculating a blood pressure value may be fitted according to the finger data, and the envelope curves corresponding to different reference users may be analyzed to obtain an ideal envelope curve. The ideal environment is understood to be an environment which is not interfered by the outside and is accurate with reference to the user operation, and the finger data comprises: different pressure values to which the finger is subjected, and blood vessel volume variation acquired under the action of the different pressure values. Considering that for the same person, the measured blood pressure value may be influenced by different seasons, the ideal envelope curve may include ideal envelope curves corresponding to different seasons respectively, so that when the blood pressure is measured in different seasons, different ideal envelope curves may be adopted to adapt to the influence of different seasons on the blood pressure measurement.

In a specific implementation, in order to meet the personalized features of different users, the ideal envelope curve can be adjusted and updated in combination with the personalized features of the users.

The starting point of the preset pressure interval is the envelope starting point pressure corresponding to the ideal envelope curve, for example, the starting point pressure may be the point a pressure 0 in fig. 7, and the ending point of the pressure interval is the envelope ending pressure corresponding to the ideal envelope curve, for example, the point B pressure Fn in fig. 7. Based on a preset pressure interval, a plurality of pressure values uniformly distributed in the preset pressure interval may be: and uniformly dividing the pressure interval from 0 to Fn at preset pressure intervals. The preset pressure interval can be set according to actual needs, and the specific number of the pressure values obtained through division is determined by Fn and the preset pressure interval.

Referring to fig. 8, fig. 8 is a schematic diagram of 6 pressure values that are uniformly distributed, and the 6 pressure values are respectively corresponding to P1 to P6 on the envelope curve in fig. 8, that is, the abscissa sizes corresponding to the 6 points P1 to P6.

Referring to fig. 9, fig. 9 is a schematic diagram of a pressure uniform sectional change, which can be understood as a schematic diagram of a change of external force with time, which is applied to a blood vessel of an object to be measured, it can be seen from fig. 9 that the external force applied to the blood vessel uniformly changes with time, and each external force is maintained for a period of time.

In this embodiment, the plurality of pressure values are uniformly distributed in the preset pressure interval based on the preset pressure interval, so that the plurality of regular pressure values can be obtained more simply and conveniently, and when the preset pressure interval is smaller and the number of the pressure values uniformly distributed in the preset pressure interval is larger, the acquired pressure values and the data amount of the corresponding vascular volume variation are also more, the envelope curve obtained by fitting is also more accurate, so that the calculated blood pressure value is also more accurate.

In one embodiment, the number of pressure values mentioned in step 301 are non-uniformly distributed in the preset pressure interval based on morphological features of the preset ideal envelope curve. When a plurality of pressure values unevenly distributed in a preset pressure interval are arranged according to the order of magnitude, the pressure difference value between any two adjacent pressure values, namely the pressure interval, is not completely equal. The ideal envelope curve has been described above and will not be described in detail here.

The morphological characteristics of the ideal envelope curve include critical locations and non-critical locations on the ideal envelope curve, where several pressure values are densely distributed and sparsely distributed. Wherein, the key position includes: the peak position of the ideal envelope curve may be a critical pressure interval in which the peak point may be located in the ideal envelope curve, for example, the peak point may be between 90 and 120, and the pressure values between 90 and 120 may be densely distributed, and the pressure values outside 90 and 120 may be relatively sparsely distributed. Referring to fig. 7, the peak point in the ideal envelope curve is P4, and a critical pressure interval where P4 is located may be P3 to P5.

In one example, the critical locations correspond to critical pressure intervals and the non-critical locations correspond to non-critical pressure intervals, that is, the entire pressure interval corresponding to the ideal envelope curve may be divided into critical pressure intervals and non-critical pressure intervals. The plurality of pressure values comprise first partial pressure values densely distributed at key positions and second partial pressure values sparsely distributed at non-key positions, wherein the first partial pressure values are uniformly divided at first pressure intervals based on key pressure intervals, the second partial pressure values are uniformly divided at second pressure intervals based on non-key pressure intervals, and the first pressure intervals are smaller than the second pressure intervals. That is, pressures near critical locations of the ideal envelope curve are evenly divided based on a smaller pressure interval, and pressures near non-critical locations of the ideal envelope curve may be evenly divided based on a relatively larger pressure interval. This pressure division can also be understood as a non-uniform division, since a uniform division of two different pressure intervals is combined.

For example, the envelope starting point pressure of the ideal envelope curve is 30, the envelope ending point pressure is 180, the first pressure interval is 15, the second pressure interval is 30, the critical pressure interval is 90-120, the non-critical pressure interval of 30-90 can be pressure segmented at 30-segment intervals, the critical pressure interval of 90-120 can be pressure segmented at 15-segment intervals, and the non-critical pressure interval of 120-180 can be pressure segmented at 30-segment intervals.

Optionally, the key location may further include: the left half height position of the ideal envelope curve and the right half height position of the ideal envelope curve are understood to be positions of points which are positioned at the left side of the peak point and are half the height of the peak point on the ideal envelope curve, and the right half height position is understood to be positions of points which are positioned at the right side of the peak point and are half the height of the peak point on the ideal envelope curve.

Referring to fig. 10, fig. 10 is a schematic diagram of unevenly distributed 8 pressure values, and the 8 pressure values are respectively the pressure values corresponding to points P1 to P8 on the envelope curve in fig. 10, that is, the abscissa sizes corresponding to the 8 points P1 to P8.

Referring to fig. 11, fig. 11 is a schematic diagram of a pressure non-uniform segment change, which can be understood as a schematic diagram of a time-dependent change of an external force applied to a blood vessel of an object to be measured, it can be seen from fig. 11 that the external force applied to the blood vessel varies non-uniformly with time, and each external force is maintained for a period of time. As can be seen from fig. 9 and 11, each external force has fluctuation in a small range during a period of time, and in consideration of possible interference during the application of force by a user or during the detection of pressure by the pressure sensor, the holding time period for each pressure value in this embodiment is understood as a time period during which effective data is collected within an allowable error range and a preset time period range. The preset duration range may be understood as a preset value range of the holding duration, for example, 1s to 6s or 2s to 6s. The collected effective data comprises: the pressure value and the corresponding vascular volume change are small.

In this embodiment, the plurality of pressure values are unevenly distributed in the preset pressure interval based on the morphological features of the preset ideal envelope curve, so that the morphological features of the envelope curve obtained by fitting based on the actually collected pressure values and the vascular volume variation are closer to the morphological features of the ideal envelope curve, which is beneficial to calculating and obtaining accurate blood pressure values.

In this embodiment, the envelope curve required for calculating the blood pressure is obtained by collecting the segment pressure data, and the principle is as follows: based on the sampling theorem, the signal is not substantially distorted as long as the sampling frequency is sufficient; wherein the acquired segment pressure data comprises: and a plurality of pressure values which are maintained for a preset maintaining time period and respectively corresponding vascular volume change amounts. In this embodiment, a plurality of appropriate pressure values are selected in a preset pressure interval, and a plurality of pressure values are applied to an object to be measured, so that the blood pressure data acquisition module can acquire a plurality of pressure values and corresponding vascular volume variation amounts thereof, and each applied pressure value is kept for a period of time to eliminate the influence of vascular hysteresis effect, which is beneficial to obtaining an accurate and stable envelope curve, thereby obtaining an accurate blood pressure value.

In one embodiment, step 301 of obtaining a plurality of pressure values applied to the object to be measured and vascular volume variation amounts corresponding to the plurality of pressure values respectively may be implemented by a flowchart as shown in fig. 12:

step 3011: acquiring a plurality of pressure values and blood vessel volume variation corresponding to the plurality of pressure values which are applied to an object to be tested and are uniformly distributed in a preset pressure interval based on a preset pressure interval;

step 3012: if the blood vessel volume variation amounts respectively corresponding to the pressure values and the pressure values uniformly distributed in the preset pressure interval do not meet the preset requirement, estimating a key pressure interval and a non-key pressure interval for calculating the blood pressure value of the object to be measured according to the blood vessel volume variation amounts respectively corresponding to the pressure values and the pressure values uniformly distributed in the preset pressure interval;

step 3013: selecting a plurality of first pressure values in a key pressure interval and a plurality of second pressure values in a non-key pressure interval; wherein, a plurality of first pressure values are densely distributed in a key pressure interval, and a plurality of second pressure values are sparsely distributed in a non-key pressure interval;

step 3014: and acquiring a plurality of first pressure values and a plurality of second pressure values applied to the object to be tested, and acquiring blood vessel volume variation corresponding to the first pressure values and blood vessel volume variation corresponding to the second pressure values.

The starting point and the ending point of the preset pressure interval mentioned in step 3011 are the envelope starting point pressure and the envelope ending point pressure corresponding to the preset ideal envelope curve, respectively, and the ideal envelope curve may be used for calculating the blood pressure value by referring to the related description in the above embodiment, so that the repetition of the description is avoided.

In step 3012, the preset requirement may be set according to the actual requirement, so as to measure whether the pressure values uniformly distributed in the preset pressure interval and the corresponding vascular volume variable amounts thereof are ideal data, i.e. whether an accurate blood pressure value can be obtained by calculation.

For example, if the morphological similarity between the envelope curve obtained by fitting and the ideal envelope curve is greater than a preset similarity threshold according to a plurality of pressure values and the vascular volume variation corresponding to the pressure values uniformly distributed in the preset pressure interval, that is, the morphological similarity between the envelope curve obtained by fitting and the ideal envelope curve is higher, the plurality of pressure values and the vascular volume variation corresponding to the pressure values uniformly distributed in the preset pressure interval can be considered to meet the preset requirement.

For another example, if the plurality of pressure values and the corresponding vascular volume changes thereof uniformly distributed in the preset pressure interval do not include the pressure values and the corresponding vascular volume changes thereof in the key pressure interval for calculating the blood pressure value of the object to be measured, it may be determined that the plurality of pressure values and the corresponding vascular volume changes thereof uniformly distributed in the preset pressure interval do not meet the preset requirement. The critical pressure value interval and the non-critical pressure interval for calculating the object to be measured can be determined according to a plurality of pressure values uniformly distributed in the preset pressure interval and the corresponding vascular volume variation thereof. Specifically, the two largest vascular volume variable amounts V1 and V2 among the vascular volume variable amounts respectively corresponding to the plurality of pressure values uniformly distributed in the preset pressure interval may be determined, then the pressure values P1 and P2 corresponding to V1 and V2 are respectively determined, and the critical pressure interval may include intervals [ P1, P2]. However, the critical pressure interval may also include other intervals according to actual needs, which are not particularly limited in this embodiment. The non-critical pressure interval may include: and the preset pressure intervals are other than the key pressure interval.

In step 3013, the first pressure values are densely distributed in the critical pressure interval, and the second pressure values are sparsely distributed in the non-critical pressure interval, by: the method comprises the steps of uniformly dividing pressure values in a key pressure interval based on a preset first pressure interval to obtain a plurality of first pressure values, uniformly dividing pressure values in a non-key pressure interval based on a preset second pressure interval to obtain a plurality of second pressure values, wherein the preset first pressure interval is smaller than the preset second pressure interval, that is, the plurality of first pressure values can be uniformly distributed in the key pressure interval, the plurality of second pressure values can be uniformly distributed in the non-key pressure interval, and the distribution of the plurality of first pressure values is denser. However, the present invention is not limited thereto, the first pressure values may be unevenly distributed in the critical pressure interval, the second pressure values may be unevenly distributed in the non-critical pressure interval, and the density of the uneven distribution of the first pressure values is higher than the density of the uneven distribution of the second pressure values.

After the first pressure values and the second pressure values are selected, the force application object can be controlled to apply the first pressure values and the second pressure values to the measurement part of the object to be measured, so that the first pressure values and the second pressure values acquired by the pressure sensor can be acquired in step 3014, and the blood vessel volume variation corresponding to the first pressure values and the blood vessel volume variation corresponding to the second pressure values can be acquired according to the PPG signals acquired by the PPG sensor. For the blood pressure data acquisition module of the active pressing type of the user, the force application object can be the user, namely the object to be measured, and the electronic equipment can prompt a plurality of first pressure values and a plurality of second pressure values which should be applied by the object to be measured through the display interface. For the cuff/air bag type blood pressure data acquisition module, the application object may be an electronic device, for example, a cuff/air bag in the electronic device, and the electronic device may control the inflation amount and/or the deflation amount of the cuff/air bag so as to apply a plurality of first pressure values and a plurality of second pressure values to the measurement portion of the object to be measured. In a specific implementation, a correspondence between the inflation amount and/or the deflation amount and the pressure value may be preset, and the electronic device may obtain, according to the correspondence, the inflation amount and/or the deflation amount of the cuff/airbag to be controlled in order to apply a pressure value.

In one example, where step 301 is implemented as a flowchart in fig. 12, step 302 may be implemented by: and fitting according to the acquired first pressure values, the second pressure values and the blood vessel volume variation corresponding to the first pressure values and the blood vessel volume variation corresponding to the second pressure values to obtain an envelope curve for calculating the blood pressure value of the object to be measured, and calculating according to the envelope curve to obtain the blood pressure value of the object to be measured.

In an example, the first pressure values and the second pressure values selected in step 3013 may be different from the pressure values uniformly distributed in the preset pressure interval based on the preset pressure interval in step 3011, so that repeated acquisition of the same pressure values and corresponding vascular volume variation amounts is avoided, which is beneficial to shortening the data acquisition time. In this case, step 302 may be implemented by: according to the obtained pressure values and the corresponding vascular volume variable quantity thereof, the first pressure values and the corresponding vascular volume variable quantity thereof, and the second pressure values and the corresponding vascular volume variable quantity thereof which are uniformly distributed in the preset pressure interval based on the preset pressure interval, fitting to obtain an envelope curve for calculating the blood pressure value, and calculating the blood pressure value. In the example, more data can be combined to fit a more accurate envelope curve for calculating the blood pressure value, so that the accuracy of the calculated blood pressure value is improved.

In this embodiment, a uniform segmentation mode in which a plurality of pressure values are uniformly distributed in a preset pressure interval is preferentially adopted, and if the uniform segmentation mode can adopt ideal data, namely data meeting preset requirements, a non-uniform segmentation mode in which a plurality of pressure values are non-uniformly distributed in the preset pressure interval is not required to be adopted subsequently; if the data acquired by adopting the uniform segmentation mode does not meet the preset requirement, the non-uniform segmentation mode is adopted next, namely, the important data area is the dense part of the pre-estimated critical pressure interval segments, and the non-important data area is the sparse part of the pre-estimated non-critical pressure interval segments. The combination of the uniform segmentation and the non-uniform segmentation is beneficial to improving the accuracy of the calculated blood pressure value while reducing the time required for acquiring ideal data.

In one embodiment, the order in which the several pressure values are applied is a sequencing, the sequencing comprising: increasing or decreasing. That is, the order in which the several pressure values are applied may be from small to large or from large to small. Referring to fig. 13 and 14, fig. 13 is a schematic diagram of the sequence of several pressure values from small to large in the process of collection, that is, the schematic diagram of the pressure stepwise change from small to large with the change of time. Fig. 14 is a schematic diagram showing the sequence of several pressure values from large to small in the acquisition process, namely, the schematic diagram showing the stepwise change of the pressure from large to small in the time course.

In one embodiment, the order in which the plurality of pressure values are applied is non-ordered, i.e. it is understood that the order in which the plurality of pressure values are applied is not from small to large nor from large to small, for example, a schematic diagram in which the order in which the plurality of pressure values are non-ordered during the acquisition process may refer to fig. 15, and fig. 15 may also be understood as a schematic diagram in which the non-ordered pressure varies in segments over time.

In the case where the order in which the several pressure values are applied is non-sequential, the reference in step 302 is made to: obtaining a blood pressure value of an object to be measured according to a plurality of pressure values and blood vessel volume variation corresponding to the plurality of pressure values, wherein the blood pressure value comprises: sorting the pressure values in ascending or descending order; and obtaining the blood pressure value of the object to be measured according to the sequenced pressure values and the vascular volume variation corresponding to the pressure values. By ordering the plurality of pressure values in ascending or descending order, it is convenient to fit an envelope curve for calculating the blood pressure value.

In this embodiment, since the electronic device sorts the plurality of pressure values according to the ascending or descending order when performing data processing, and obtains the blood pressure value of the object to be measured based on the blood vessel volume variation corresponding to the sorted plurality of pressure values and the plurality of pressure values, the user can apply pressure to the blood vessel by using different pressing forces at will, without stably increasing or stably decreasing the applied pressing force, and the operation difficulty of the user for blood pressure detection is greatly reduced, so that the efficiency and accuracy of blood pressure measurement can be improved. For the user, the pressing operation is simpler and more convenient, so that the user experience can be improved.

In this embodiment, the user does not need to operate slowly, and only needs to sequentially maintain the pressures of each size according to the prompt of the interactive interface, so that a complete envelope curve can be obtained, and the blood pressure measurement of the user can be completed quickly and accurately. Namely, the scheme for measuring the blood pressure by collecting the sectional pressure data in the embodiment has the advantages of short collection time and good user experience, can overcome errors possibly caused by vascular hysteresis, and cannot deteriorate the overall performance. Referring to tables 1 and 2, table 1 is a blood pressure measurement of a linear change in pressure in the prior art, and table 2 is a blood pressure measurement of a piecewise change in pressure (i.e., each pressure value applied for a period of time) provided by an embodiment of the present application:

TABLE 1

	MAE	MD	SD
				Predicting systolic blood pressure	5.897652229	0.463854	8.055035
Predicting diastolic pressure	6.318760692	4.549675	7.612584

TABLE 2

	MAE	MD	SD
				Predicting systolic blood pressure	5.252771899	0.771083	6.927803
Predicting diastolic pressure	5.885391895	4.211872	6.5502

In tables 1 and 2, MD is the average error, SD is the standard deviation, MAE is the average absolute error, and MAE, MD, SD is as small as possible. As can be seen in combination with tables 1 and 2: for MAE, MD, SD, a pressure step change blood pressure measurement is better than a pressure linear change blood pressure measurement. In a specific implementation, MAE, MD, SD can be calculated by the following formula:

Wherein P is _i For the ith measurement value, P _si For the ith reference value, MD is the mean error, SD is the standard deviation, and MAE is the mean absolute error.

The above steps of the methods are divided, for clarity of description, and may be combined into one step or split into multiple steps when implemented, so long as they include the same logic relationship, and they are all within the protection scope of this patent; it is within the scope of this patent to add insignificant modifications to the algorithm or flow or introduce insignificant designs, but not to alter the core design of its algorithm and flow.

The embodiment of the present application further relates to a chip, and referring to fig. 16, the chip 401 is connected to a memory 402, where the memory stores instructions executable by the chip, and the instructions are executed by the chip, so that the chip can execute the blood pressure acquisition method in the above embodiment.

Where memory 402 and chip 401 are connected by a bus, the bus may include any number of interconnected buses and bridges, which connect together the various circuits of one or more of the chips 401 and memory 402. The bus may also connect various other circuits such as peripherals, voltage regulators, and power management circuits, which are well known in the art, and therefore, will not be described any further herein. The bus interface provides an interface between the bus and the transceiver. The transceiver may be one element or may be a plurality of elements, such as a plurality of receivers and transmitters, providing a means for communicating with various other apparatus over a transmission medium. The data processed by the chip 401 is transmitted over a wireless medium via an antenna, which further receives and transmits the data to the chip 401.

The chip 401 is responsible for managing the bus and general processing and may also provide various functions including timing, peripheral interfaces, voltage regulation, power management, and other control functions. And memory 402 may be used to store data used by chip 401 in performing operations.

The embodiment of the application also relates to an electronic device, referring to fig. 16, comprising: the chip 401 described above, and a memory 402 connected to the chip 401.

The embodiment of the application also relates to a computer readable storage medium which stores a computer program. The computer program implements the above-described method embodiments when executed by a processor.

That is, it will be understood by those skilled in the art that all or part of the steps in implementing the methods of the embodiments described above may be implemented by a program stored in a storage medium, where the program includes several instructions for causing a device (which may be a single-chip microcomputer, a chip or the like) or a processor (processor) to perform all or part of the steps in the methods of the embodiments of the application. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a random access Memory (RAM, random Access Memory), a magnetic disk, or an optical disk, or other various media capable of storing program codes.

It will be understood by those of ordinary skill in the art that the foregoing embodiments are specific examples of carrying out the application and that various changes in form and details may be made therein without departing from the spirit and scope of the application.

Claims (11)

1. A blood pressure data acquisition apparatus for measuring a blood pressure value of a subject to be measured, the apparatus comprising: the blood pressure data acquisition module comprises a pressure sensor and a PPG sensor;

the pressure sensor is used for acquiring a plurality of pressure values applied to the object to be detected;

the PPG sensor is used for acquiring blood vessel volume variation corresponding to the pressure values respectively;

the time length of the applied pressure values is respectively kept to be preset keeping time length, and the keeping time length is longer than or equal to the time length required for eliminating the influence of the vascular hysteresis effect so as to acquire effective vascular volume variation corresponding to the pressure values;

the chip is used for obtaining the blood pressure value of the object to be measured according to the pressure values and the blood vessel volume variation corresponding to the pressure values;

The plurality of pressure values are uniformly distributed in a preset pressure interval based on a preset pressure interval;

the chip is further used for estimating a key pressure interval and a non-key pressure interval for calculating the blood pressure value of the object to be measured according to the blood vessel volume variation corresponding to the plurality of pressure values and the plurality of pressure values which are uniformly distributed in the preset pressure interval when the plurality of pressure values and the blood vessel volume variation corresponding to the plurality of pressure values which are uniformly distributed in the preset pressure interval do not meet the preset requirement;

selecting a plurality of first pressure values in the key pressure interval, and selecting a plurality of second pressure values in the non-key pressure interval; wherein the first pressure values are densely distributed in the critical pressure interval, and the second pressure values are sparsely distributed in the non-critical pressure interval;

the first pressure values and the second pressure values applied to the object to be detected are obtained, and the blood vessel volume variation corresponding to the first pressure values and the blood vessel volume variation corresponding to the second pressure values are obtained.

2. The blood pressure data collection device of claim 1, wherein the plurality of pressure values are unevenly distributed in a preset pressure interval based on morphological features of a preset ideal envelope curve.

3. The blood pressure data collection device of claim 2, wherein the morphological features of the preset ideal envelope curve include critical locations and non-critical locations;

the plurality of pressure values are densely distributed at the key positions and sparsely distributed at the non-key positions.

4. A blood pressure data acquisition device according to any one of claims 1 to 3, wherein the start point and the end point of the preset pressure interval are respectively an envelope start point pressure and an envelope end point pressure corresponding to a preset ideal envelope curve; the ideal envelope curve is used to calculate a blood pressure value.

5. The blood pressure data collection device according to claim 1, wherein the holding time period has a value ranging from: 1 s-6 s.

6. The blood pressure data collection device of claim 5, wherein the holding time period has a range of values: 2 s-6 s.

7. The blood pressure data collection device of claim 6, wherein the hold time period is 3s.

8. The blood pressure data collection device of claim 1, wherein the order in which the number of pressure values are applied is sequenced or non-sequenced;

the sequencing includes: increasing or decreasing.

9. The blood pressure data collection device of claim 8, wherein,

the chip is also used for sorting the pressure values according to an ascending or descending order; and obtaining the blood pressure value of the object to be measured according to the sequenced pressure values and the blood vessel volume variation corresponding to the pressure values.

10. The blood pressure data collection device of claim 1, wherein,

the chip is further used for displaying a pressing prompt message through an interactive interface before the blood vessel volume change amounts corresponding to the pressure values are obtained, and the pressing prompt message comprises: the pressure value to be applied in the current holding time period, the pressure value to be applied in the next holding time period or the holding time period corresponding to each applied pressure value.

11. The chip is characterized in that the chip is connected with a memory, the memory stores instructions which can be executed by the chip, and the instructions are executed by the chip, so that the chip can obtain the blood pressure value of the object to be measured according to a plurality of pressure values applied to the object to be measured and blood vessel volume variation corresponding to the plurality of pressure values, which are acquired by a blood pressure data acquisition module;

The blood pressure data acquisition module comprises a pressure sensor and a PPG sensor, wherein the pressure values are obtained through the pressure sensor, and the blood vessel volume variation is obtained through the PPG sensor;

the time length of the applied pressure values is respectively kept to be preset keeping time length, and the keeping time length is longer than or equal to the time length required for eliminating the influence of the vascular hysteresis effect so as to acquire effective vascular volume variation corresponding to the pressure values;

the plurality of pressure values are uniformly distributed in a preset pressure interval based on a preset pressure interval;

the chip is further used for estimating a key pressure interval and a non-key pressure interval for calculating the blood pressure value of the object to be measured according to the blood vessel volume variation corresponding to the plurality of pressure values and the plurality of pressure values which are uniformly distributed in the preset pressure interval when the plurality of pressure values and the blood vessel volume variation corresponding to the plurality of pressure values which are uniformly distributed in the preset pressure interval do not meet the preset requirement;

selecting a plurality of first pressure values in the key pressure interval, and selecting a plurality of second pressure values in the non-key pressure interval; wherein the first pressure values are densely distributed in the critical pressure interval, and the second pressure values are sparsely distributed in the non-critical pressure interval;

The first pressure values and the second pressure values applied to the object to be detected are obtained, and the blood vessel volume variation corresponding to the first pressure values and the blood vessel volume variation corresponding to the second pressure values are obtained.