CN106108877B - A kind of survey meter of blood pressure - Google Patents
A kind of survey meter of blood pressure Download PDFInfo
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- CN106108877B CN106108877B CN201610389439.7A CN201610389439A CN106108877B CN 106108877 B CN106108877 B CN 106108877B CN 201610389439 A CN201610389439 A CN 201610389439A CN 106108877 B CN106108877 B CN 106108877B
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- 230000036772 blood pressure Effects 0.000 title claims abstract description 91
- 230000010355 oscillation Effects 0.000 claims abstract description 59
- 238000000605 extraction Methods 0.000 claims abstract description 20
- 238000000034 method Methods 0.000 claims abstract description 19
- 230000008859 change Effects 0.000 claims description 29
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- 230000005540 biological transmission Effects 0.000 claims description 7
- 238000004364 calculation method Methods 0.000 claims description 7
- 238000007872 degassing Methods 0.000 claims description 5
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- 230000004069 differentiation Effects 0.000 claims description 3
- 230000000740 bleeding effect Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 abstract description 29
- 238000009530 blood pressure measurement Methods 0.000 abstract description 10
- 230000000903 blocking effect Effects 0.000 abstract description 3
- 210000002302 brachial artery Anatomy 0.000 abstract description 3
- 230000000694 effects Effects 0.000 description 7
- 230000035488 systolic blood pressure Effects 0.000 description 7
- 238000012360 testing method Methods 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000006837 decompression Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 230000035487 diastolic blood pressure Effects 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 206010020772 Hypertension Diseases 0.000 description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
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- 208000031104 Arterial Occlusive disease Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000005434 White Coat Hypertension Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 238000000540 analysis of variance Methods 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 208000021328 arterial occlusion Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
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- 238000006243 chemical reaction Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
- A61B5/0225—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers the pressure being controlled by electric signals, e.g. derived from Korotkoff sounds
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Abstract
The invention discloses a kind of survey meter of blood pressure, including fingerstall, oversleeve, cuff pressure sensor assembly, oversleeve pressure sensor module, gas source module, AD acquisition modules, processor module etc., wherein, reason device module includes linear control unit, wave of oscillation extraction unit and the blood pressure parameter calculating part of inflating；It is linear to inflate control unit, for controlling fingerstall or cuff to realize different mode of operations；Wave of oscillation extraction unit, linear the pressure oscillation ripple signal that control unit obtained is inflated for extracting.The survey meter of blood pressure of the present invention uses the blood pressure measurement methods that finger fingerstall pressurizes, and without blocking brachial artery flow, maximum possible reduces the influence to patient, the influence in especially sleeping；Blood pressure is calibrated using pulse wave blood pressure collimation technique (cuff+fingerstall), measurement accuracy degree is improved.
Description
Technical field
The present invention relates to blood pressure measurement device, and in particular to a kind of survey meter of blood pressure.
Background technology
Angiocardiopathy (Cardiovascular disease, CVD) current developed country's death rate holds pride of place
Important diseases, are also the class disease of death rate highest one in China, the World Health Organization has been classified as the 21 century harm mankind
The number one killer of health, it has become the major public health problem in China and the world.The health of serious influence people and
Quality of life, therefore, early prediction and mid-term diagnoses and treatment to angiocardiopathy have and its important meaning.
Blood pressure is the weight for reflecting the physiological parameters such as cardiac pumping function, vascular resistence, viscosity of blood and whole body blood volume
Index is wanted, is clinically widely applied.Blood pressure have significantly changes over time characteristic, clinic progress single or
The situation that few blood pressure measurement can not reliably reflect under the fluctuation and active state of blood pressure.Ambulatory blood pressure monitoring is at 24 hours
A kind of diagnostic techniques of blood pressure under interior automatic discontinuous property Timing measurement daily life state.Because ambulatory blood pressure overcomes clinic blood
The limitation of less pendulous frequency, the error of observation and White coat effect etc. is pressed, can objectively reflect the real standard and ripple of blood pressure
Dynamic situation, therefore make a definite diagnosis in clinical doubtful hyperpietic, judge " white coat hypertension " and intractable hypertension, the anti-height of evaluation
Obtain increasingly being widely applied in terms of the curative effect and guiding treatment of blood pressure medication.Ambulatory blood pressure monitoring typically uses oscillography
Method, it is a kind of Techniques of Non-Invasive Blood Pressure Measurement, can be using decompression measurement and boosting measurement both of which.Decompression measurement be first to
Cuff, which is inflated, is forced into arterial occlusion, then in deflation course, collection pressure oscillation ripple in the cuff that arterial pulse is produced
Signal；And measurement of boosting is to gather the pressure oscillation ripple signal in cuff simultaneously in cuff pressure process.Oscillographic method measurement is logical
Frequently with curve fitting algorithm and amplitude coefficient is coordinated to calculate pressure value, detailed process is:First by the peak value sequence of the wave of oscillation
Row carry out curve fitting, static pressure (flip-flop of pressure in cuff) value, as mean pressure corresponding to matched curve maximum；
Systolic pressure amplitude and diastolic pressure amplitude are obtained using maximum amplitude and amplitude coefficient, is then obtained by matched curve corresponding quiet
Pressure value, as systolic pressure and diastolic pressure.
Conventional dynamic blood pressure instrument is that Timing measurement is added on the basis of electronic sphygmomanometer, and reduces the body of sphygmomanometer
Product, to reach the 24 hours blood pressure information of acquisition that is easy to carry.It is limited in that measurement brachial arterial pressure influences on sleep
Larger, nighttime blood pressures measurement accuracy is vulnerable to influence, while measurement frequency is relatively low, if effective pendulous frequency deficiency measurement sum
70%, measurement data is then invalid.
Existing pressure oscillation ripple is mostly using upper arm cuff measuring method, it is necessary to which a period of time blocks arteria brachialis blood completely
The noise that stream, the multiple extravasated blood for measuring the numbness and measurement position that will cause whole upper arm, and pump are sent during quickly inflating
It is larger, easily user's sleep is impacted, the accuracy of influence night measurement.Meanwhile, existing pressure oscillation ripple is adopted mostly
With decompression measuring method, cause single measurement overlong time (45-60s), Consumer's Experience is poor.
Patent document CN101612039A discloses a kind of self-adaption blood pressure detector, and the device can be according to measured
The linear aeration speed of heart rate automatic adjusument, eliminate influence of the individual difference to testing result, detection time is short, testing result
Accurately.But the device is mainly the speed linearly inflated is adjusted by the heart rate according to measured, testing result it is accurate
Property has much room for improvement.
The content of the invention
In view of the shortcomings of the prior art, the purpose of the present invention, which is aimed to provide, a kind of can not only improve users'comfort but also can be with
Ensure the survey meter of blood pressure of testing result accuracy.
To achieve the above object, the present invention is adopted the following technical scheme that：
A kind of survey meter of blood pressure, including
Fingerstall with air bag, it is looped around on the first determination part, the initial pressure vibration for obtaining the first determination part
Ripple signal；
Cuff pressure sensor assembly, the pressure oscillation ripple signal for fingerstall to be obtained is converted to voltage signal, including
Cuff pressure sensor；
Cuff, it is looped around on determination part, the initial pressure wave of oscillation signal for obtaining the second determination part；
Cuff pressure sensor assembly, the pressure oscillation ripple signal for cuff to be obtained is converted to voltage signal, including
Cuff pressure sensor；
Gas source module, is connected by main gas circuit with fingerstall and cuff, is that air bag and cuff provide source of the gas, including gas
Pump；
AD acquisition modules, the voltage signal for collecting cuff pressure sensor assembly or cuff pressure sensor assembly,
And voltage signal is converted into data signal；
Processor module, for handling the signal that AD acquisition modules are gathered；
Processor module includes linear control unit, wave of oscillation extraction unit and the blood pressure parameter calculating part of inflating；
It is linear to inflate control unit, fingerstall or cuff is realized different mode of operations by controlling gas source module；
Wave of oscillation extraction unit, for being extracted to the data signal produced by AD acquisition modules, obtains final to analyze
Pressure oscillation ripple signal；
Blood pressure parameter calculating part, is calculated for the final pressure wave of oscillation signal obtained according to wave of oscillation extraction unit
Go out blood pressure parameter value.
It is above-mentioned it is linear inflate control unit be used to controlling gas source module make fingerstall or cuff realize first it is linear inflate pattern and
Second it is linear inflate pattern, and linearly inflate air bag in pattern or the pressure change rate K in cuff for setting first1Most
Big pressure P1And second linear air bag in pattern or the pressure change rate K in cuff of inflating2With maximum pressure P2Value；Wherein
P1Less than P2；
The described first linear pattern of inflating is：After air bag or cuff inflation, the real-time pressure in air bag or cuff is gathered in real time
Strong P simultaneously calculates real-time pressure change rate K, is less than P in P1Before, air pump voltage U is adjusted in real time by PID to track pressure change
Rate K1, until realizing that the pressure in air bag or cuff linearly rises to P from 01；
The described second linear pattern of inflating is：It is more than P in P1And less than P2Before, air pump voltage U is adjusted in real time by PID
To track pressure change rate K2, up to realizing the pressure in air bag or cuff from P1Linearly rise to P2；When P is more than P2Afterwards, air bag or
Cuff stops inflation.
The air pump voltage U is tried to achieve by following relational expression：
U=Kp*e+Ki* ∑ e+kd* Δs e
Wherein：Kp is proportional unit coefficient；Ki is integral unit coefficient；Kd is differentiation element coefficient；Δ e is error
Differential, equal to error current and the difference of preceding first-order error；
E is control error：E=K-Kn；KnFor K1Or K2；
K=Pi-P(i-1)；PiFor current collection point pressure value, P(i-1)For the pressure of the previous collection point of current collection point
Value.
The wave of oscillation extraction unit is used to extract the data signal produced by AD acquisition modules, is obtained most with analyzing
End pressure wave of oscillation signal, specific process is：
P is chosen first1Pressure waveform data above, passes it through 3Hz low pass software filtering, then pass through least square
Method fitting obtains actual ramp signal, by P1Raw pressure signal above subtracts the ramp signal that fitting is obtained, again finally
By 0.5Hz software high-pass filtering, final pressure wave of oscillation signal is obtained.
The processor module also includes analysis of heart rate variability portion, for the most final pressure obtained according to wave of oscillation extraction unit
Forced oscillation ripple signal of change draws heart rate variability parameter value, and by the heart rate variability parameter value calculated and the heart set in advance
Rate Mutation parameter value is compared；If the heart rate variability parameter value calculated is more than the heart rate variability parameter value of setting, open
Dynamic blood pressure parameter calculating part, survey calculation pressure value；If the heart rate variability parameter value calculated is less than the heart rate variability of setting
Parameter value, then survey calculation heart rate variability parameter value always.
Above-mentioned survey meter of blood pressure also includes：
Fingerstall valve module, for control fingerstall and main gas circuit connection whether, to control charge and discharge of the gas source module to air bag
Gas, including fingerstall valve；
Cuff valve module, for control cuff and main gas circuit connection whether, to control charge and discharge of the gas source module to cuff
Gas, including cuff valve；
Uniform valve module, for realizing uniform pressure release, including at the uniform velocity valve to the gas in air bag and cuff；
Rapid degassing valve module, for realizing quick pressure releasing, including rapid-release valve to air bag and cuff.
The fingerstall valve, cuff valve, rapid-release valve and air pump are connected with four interfaces of the first four-way valve respectively；
Fingerstall valve is also connected with an interface of triple valve, and two other interface of the triple valve is passed with fingerstall and cuff pressure respectively
Sensor is connected；Cuff valve is also connected with an interface of the second four-way valve, the other three interface point of second four-way valve
It is not connected with the uniform velocity valve, cuff and cuff pressure sensor.
The AD acquisition modules include one 24 50Hz A/D converter.
Above-mentioned survey meter of blood pressure also includes user interactive module, for showing detection information in real time and receiving user
Instruction；
Data transmission module, for carrying out data transmission with mobile terminal, realizes remote control.
Above-mentioned survey meter of blood pressure also includes acceleration sensor module, for providing positioning user's posture and sleep state
Required 3-axis acceleration signal.
The beneficial effects of the present invention are：
The survey meter of blood pressure of the present invention uses the blood pressure measurement methods that finger fingerstall pressurizes, without blocking brachial artery flow,
Maximum possible reduces the influence to patient, the influence in especially sleeping；Blood pressure is surveyed using boosting fast measurement technique
Amount, single measurement only needs 15s, and Consumer's Experience is good；School is carried out to blood pressure using pulse wave blood pressure collimation technique (cuff+fingerstall)
Standard, improves measurement accuracy degree.
Brief description of the drawings
Fig. 1 is the structured flowchart of survey meter of blood pressure of the present invention；
Fig. 2 is the flow chart linearly inflated；
Fig. 3 is the flow chart that the wave of oscillation is extracted；
Fig. 4 is PID control block diagram；
Fig. 5 is linear design sketch of inflating；
Fig. 6 is the ramp signal of linear rise stage and fitting；
Fig. 7 be direct high pass after wave of oscillation signal design sketch；
Fig. 8 is the design sketch for removing the wave of oscillation signal after ramp signal and high pass；
Fig. 9 is the connection block diagram of survey meter of blood pressure gas path component of the present invention；
In figure：1st, fingerstall；2nd, cuff pressure sensor assembly；21st, cuff pressure sensor；3rd, cuff；4th, cuff pressure
Sensor assembly；41st, cuff pressure sensor；5th, gas source module；51st, air pump；6th, processor module；61st, it is linear to inflate control
Portion；62nd, wave of oscillation extraction unit；63rd, blood pressure parameter calculating part；64th, analysis of heart rate variability portion；7th, fingerstall valve module；71st, fingerstall
Valve；8th, cuff valve module；81st, cuff valve；9th, uniform valve module；91st, average rate valve；10th, Rapid degassing valve module；101st, quickly put
Air valve；11st, power transfer module；12nd, the first four-way valve；13rd, triple valve；14th, the second four-way valve；15th, family interactive module；16、
Acceleration sensor module；17th, data transmission module；18th, AD acquisition modules.
Embodiment
Below, with reference to accompanying drawing and embodiment, the present invention is described further：
As shown in Fig. 1 and Fig. 9, survey meter of blood pressure of the invention includes the fingerstall 1 with air bag, and it is looped around the first measure
In portion, the initial pressure wave of oscillation signal for obtaining the first determination part；Cuff pressure sensor assembly 2, for fingerstall to be obtained
The initial pressure wave of oscillation signal obtained is converted to voltage signal, including cuff pressure sensor 21；Cuff 3, it is looped around measure
In portion, the initial pressure wave of oscillation signal for obtaining the second determination part；Cuff pressure sensor assembly 4, for cuff 3 to be obtained
The initial pressure wave of oscillation signal obtained is converted to voltage signal, including cuff pressure sensor 41；Gas source module 5, passes through main gas
Road is connected with fingerstall 1 and cuff 3, is that air bag and cuff provide source of the gas, including air pump 51；AD acquisition modules 18, can be used
Single-chip microcomputer, FPGA, ARM etc., for gathering the voltage on cuff pressure sensor assembly 2 and cuff pressure sensor assembly 4
Other signals such as the battery electric quantity and temperature of signal and this survey meter of blood pressure, and corresponding voltage signal is converted into numeral
Signal；Processor module 6, the signal for handling the collection of AD acquisition modules 18；Processor module 6 includes linear control unit of inflating
61, wave of oscillation extraction unit 62 and blood pressure parameter calculating part 63；It is linear to inflate control unit 61, for controlling fingerstall 1 or cuff 3 real
Existing different mode of operation；Wave of oscillation extraction unit 62, for being extracted to the data signal produced by AD acquisition modules 18, with
Analysis obtains final pressure wave of oscillation signal；Blood pressure parameter calculating part 63, for being obtained most according to wave of oscillation extraction unit 62
End pressure wave of oscillation signal and calculate blood pressure parameter value.
The survey meter of blood pressure of the present invention has following several mode of operations：
1st, correction mode
Booster air pump 51, inflates simultaneously to cuff 3 and fingerstall 1, and fingerstall 1 only needs to maintain lower pressure (50mmHg) to survey
Feel one's pulse ripple, so when fingerstall 1 reaches the pressure value of setting, such as during 45-55mmHg, air pump 51 then suspends to fingerstall 1 dozen
Gas, and preserve pressure in fingerstall 1；Air pump 51 then continues to inflate to cuff 3, until the pressure in cuff exceedes systolic pressure (normally
The systolic pressure value of people is probably 110-130mmHg), homogenous linear deflation then is carried out to cuff 31, until the pressure in cuff
Less than systolic pressure, the first pulse crest value that detect adopted by cuff pressure sensor in the cuff pressure signal collected is
Systolic pressure after calibration, then Rapid degassing is carried out to cuff and air bag by vent valve, complete correction work.
2nd, fingerstall, which works independently, measures blood pressure
After the completion of the survey meter of blood pressure calibration of the present invention, as shown in Figure 2, it is necessary to which fingerstall 1, then surround by initialization apparatus
On the finger of user；Again by the Working mode set of fingerstall 1 be first it is linear inflate pattern and second it is linear inflate pattern, and
The pressure change rate K that setting first is linearly inflated in pattern in the air bag of fingerstall 11(such as 40/fs) and maximum pressure P1(such as 40mmHg)
And the second linear pressure change rate K inflated in pattern in the air bag of fingerstall 12(such as 120/ (14*fs)) and maximum pressure P2(such as
160mmHg)；
In addition, in order to be able to farthest shorten time of measuring, as shown in figure 5, the first linear pattern of inflating can be set
Quickly to inflate the stage (pressure from 0 to 40mmHg, about 1s), second it is linear inflate pattern to inflate the stage at a slow speed (pressure from
40 to 160mmHg, about 14s).That is, by the way of being realized and linearly inflating using survey meter of blood pressure of the present invention, single
The time of measurement only needs 15S or so, or even shorter, and (time of single measurement needs 45-60s with existing decompression measuring method
) time of measuring is significantly shortened, so as to significantly improve the comfort level of user.Certainly, above-mentioned first is linear
Inflate pattern and the second linear time of measuring for inflating pattern, different values can be set according to the demand of different user.
Air pump 51 starts, and the collection in real time of cuff pressure sensor 21 and AD acquisition modules 18 refers to pressure P in air bag simultaneously
Pressure change rate K is calculated, is less than P in P1Before, air pump voltage U is adjusted in real time by PID to track target, pressure rate of change K1,
Until realizing that the first linear pressure inflated in pattern in the air bag of fingerstall 1 linearly rises to P from 01；
Similarly, it is more than P in P1And less than P2Before, air pump voltage U is adjusted in real time by PID to track target, pressure change
Rate K2, until realizing the second linear pressure inflated in pattern in the air bag of fingerstall 1 from P1Linearly rise to P2；
As P is more than P2, then air pump 51 stop inflate.
That is, linear inflate of fingerstall 1 controls air pump by PID to realize in real time, it is specific as shown in figure 4,
Using the real-time change rate K of pressure in the air bag of fingerstall 1 as PID control amount, by giving pressure change rate sets target value (K1With
K2), compared with feeding back obtained current real-time pressure change rate K, obtain the input quantity for controlling error as PID control, then
Calculated by increment type PID and obtain output quantity, control air pump 1, which is adjusted, to be output to the tolerance Q of air bag (air pump is output to the gas of air bag
Q is measured mainly by controlling the voltage of air pump to realize), detect the pressure in air bag to enter finally by cuff pressure sensor
PID is adjusted row next time.In this way, by carrying out feedback adjustment to the rate of change k measured in real time, can accurately ensure to be surveyed
The accuracy for the pressure measured, thereby may be ensured that the stability and accuracy of air pressure wave of oscillation signal.
Wherein, above-mentioned air pump voltage U is tried to achieve by following relational expression：
U=Kp*e+Ki* ∑ e+kd* Δs e
Wherein：Kp is proportional unit coefficient；Ki is integral unit coefficient；Kd is differentiation element coefficient；Δ e is micro- for error
Point, equal to error current and the difference of preceding first-order error；
E is control error：E=K-Kn；KnFor K1Or K2；
K=Pi-P(i-1)；PiFor current collection point pressure value, P(i-1)For the pressure of the previous collection point of current collection point
Value.
By above-mentioned relational expression, the voltage U of air pump can be accurately controlled, and then air pump regulation can be accurately controlled
It is output to the tolerance Q of air bag.
Meanwhile, wave of oscillation extraction unit 62 can be extracted final to obtain to the data signal produced by AD acquisition modules 18
Pressure swings ripple signal, as shown in figure 3, the extraction flow of the final pressure wave of oscillation is：P is chosen first1Pressure waveform above
Data, pass it through 3Hz low pass software filtering, then obtain actual ramp signal by least square fitting, by P1With
On raw pressure signal subtract the obtained ramp signal of fitting, as shown in fig. 6, the envelope effect of the wave of oscillation is good, and algorithm letter
It is single, realized beneficial on single-chip microcomputer；Finally pass through 0.5Hz software high-pass filtering again, you can obtain final pressure wave of oscillation letter
Number, effect is as shown in Figure 8.The wave of oscillation effect obtained using survey meter of blood pressure of the present invention is significantly better than using traditional blood pressure measurement
Instrument grasps obtained wave of oscillation effect using bandpass filter, and effect is specifically as shown in Figure 7.
Finally, the final pressure wave of oscillation signal meter that blood pressure parameter calculating part 63 can be obtained according to wave of oscillation extraction unit 62
Calculation draws blood pressure parameter value, such as mean pressure, diastolic pressure, systolic pressure.
3rd, cuff, which works independently, measures blood pressure
Cuff work independently with fingerstall work independently measuring blood pressure the course of work it is consistent, just do not repeating herein.
From the foregoing, the survey meter of blood pressure of the present invention has following technical advantage：
1st, blood pressure instrument of the invention, the blood pressure measurement methods pressurizeed using finger fingerstall, without blocking brachial artery flow, most
Greatly may influence of the reduction to patient, the influence in especially sleeping；
2nd, survey meter of blood pressure of the invention, fingerstall uses the scheme without photoelectric sensor, and fingerstall is worn and easy to use, profit
Used in family；
3rd, survey meter of blood pressure of the invention, as a result of small pump and fingerstall ballonet, volume and more traditional dynamic of power consumption
State blood pressure instrument is reduced；
4th, survey meter of blood pressure of the invention, is measured, single measurement is only needed using boosting fast measurement technique to blood pressure
15s is wanted, Consumer's Experience is good；
5th, survey meter of blood pressure of the invention, is calibrated using pulse wave blood pressure collimation technique (cuff+fingerstall) to blood pressure,
Improve measurement accuracy degree.
In addition, effective pendulous frequency in order to improve this survey meter of blood pressure, also sets up intentionally in above-mentioned processor module 6
Rate analysis of variance portion 64, the pressure oscillation ripple signal of change for being obtained according to wave of oscillation extraction unit 62 show that heart rate variability is joined
Numerical value, and the heart rate variability parameter value calculated is compared with heart rate variability parameter value set in advance；If calculating
The heart rate variability parameter value gone out is more than the heart rate variability parameter value of setting, then starts blood pressure parameter calculating part, survey calculation blood pressure
Value；If the heart rate variability parameter value calculated is less than the heart rate variability parameter value of setting, always survey calculation heart rate variability
Parameter value.That is, the survey meter of blood pressure of the present invention also has the mode of operation of a measurement heart rate, the heart rate of user can be entered
Row measurement, meanwhile, it can be judged whether to carry out blood pressure measurement to the blood pressure of user according to the result of measurement, to ensure blood pressure measurement
Effective degree.Empirical tests, using the survey meter of blood pressure of the present invention, its effective pendulous frequency reaches the 99% of overall measurement number of times
More than, it is ensured that the validity of measurement data, from so as to solve existing survey meter of blood pressure nighttime blood pressures measurement accuracy easily by
To the technical problem of influence.
Wherein, return shown in Fig. 1 and Fig. 9, in this survey meter of blood pressure, in addition to fingerstall valve module 7, for controlling fingerstall
Whether is connection with main gas circuit, to control gas source module 5 to the inflation/deflation of air bag, including fingerstall valve 71；Cuff valve module 8, is used
In control cuff 3 and main gas circuit connection whether, to control gas source module 5 to the inflation/deflation of cuff 3, including cuff valve 81；
Even valve module 9, for realizing uniform pressure release, including at the uniform velocity valve 91 to the gas in air bag and cuff 3；Rapid degassing valve module
10, for realizing quick pressure releasing, including rapid-release valve 101 to air bag and cuff 3；In addition to a Power convert mould certainly,
Block 11, to provide electricity for above-mentioned modules, realizes cell voltage to the conversion of each target voltage.
As shown in figure 9, above-mentioned fingerstall valve 72, cuff valve 81, rapid-release valve 101 and air pump 51 are respectively with the one or four
Four interfaces of port valve 12 are connected；Fingerstall valve 72 is also connected with an interface of triple valve 13, and the triple valve 13 is in addition
Two interfaces are connected with fingerstall 1 and cuff pressure sensor 21 respectively；Cuff valve 81 also connects with one of the second four-way valve 14
Mouthful be connected, the other three interface of second four-way valve 14 respectively with the uniform velocity valve 91, cuff 3 and cuff pressure sensor 41
It is connected.That is, the present invention is by dexterously utilizing two four-way valves and a triple valve by each valve of the present invention, gas
Pump and cuff pressure sensor, cuff pressure sensor link together, to allow this survey meter of blood pressure to have difference
Mode of operation, protect the accuracy for further having demonstrate,proved comfortableness that this survey meter of blood pressure uses and testing result.
Wherein, above-mentioned AD acquisition modules 18 include the A/D converter and supporting auxiliary circuit for being 24 50Hz, adopt
With 24 A/D converters without dynamic gain and related modulate circuit, hardware, it is possible to reduce the complexity and circuit filtering of circuit
Caused wave distortion, user adaptation is good, can be effectively prevented from air pump and produce noise.
Wherein, return again to shown in Fig. 1, this survey meter of blood pressure also includes user interactive module 15, for showing inspection in real time
Measurement information and reception user instruction so that this survey meter of blood pressure has more hommization
This survey meter of blood pressure also includes acceleration sensor module 16, for providing positioning user's posture and sleep state institute
The 3-axis acceleration signal needed, including acceleration transducer.To obtain the posture of user, so as to decide whether to survey again
Take blood pressure, reduce the possibility of measuring error, while the depth of sleep can be obtained by acceleration transducer, can be as pre-
One of factor that measuring blood pressure changes, so that the frequency of change blood pressure measurement.
This survey meter of blood pressure also includes data transmission module 17, for carrying out data transmission with mobile terminal, realizes long-range
Control, can use wireless and wired method, including wireless such as bluetooth, wired such as serial ports, USB.
It will be apparent to those skilled in the art that technical scheme that can be as described above and design, make other various
It is corresponding to change and deformation, and all these change and deformation should all belong to the protection domain of the claims in the present invention
Within.
Claims (8)
1. a kind of survey meter of blood pressure, it is characterised in that including
Fingerstall with air bag, it is looped around on the first determination part, the initial pressure wave of oscillation letter for obtaining the first determination part
Number；
Cuff pressure sensor assembly, the pressure oscillation ripple signal for fingerstall to be obtained is converted to voltage signal, including fingerstall
Pressure sensor；
Cuff, it is looped around on determination part, the initial pressure wave of oscillation signal for obtaining the second determination part；
Cuff pressure sensor assembly, the pressure oscillation ripple signal for cuff to be obtained is converted to voltage signal, including cuff
Pressure sensor；
Gas source module, is connected by main gas circuit with fingerstall and cuff, is that air bag and cuff provide source of the gas, including air pump；
AD acquisition modules, the voltage signal for collecting cuff pressure sensor assembly or cuff pressure sensor assembly, and will
Voltage signal is converted to data signal；
Processor module, for handling the signal that AD acquisition modules are gathered；
Processor module includes linear control unit, wave of oscillation extraction unit and the blood pressure parameter calculating part of inflating；
It is linear to inflate control unit, fingerstall and/or cuff is realized different mode of operations by controlling gas source module：Straightening die
Formula, fingerstall, which work independently, measures blood pressure and cuff works independently and measures blood pressure；Wherein, the correction mode is：
Linear control unit of inflating controls gas source module to cuff and fingerstall while inflating；
Wave of oscillation extraction unit, for being extracted to the data signal produced by AD acquisition modules, to analyze acquisition final pressure
Wave of oscillation signal；
Blood pressure parameter calculating part, bleeding is calculated for the final pressure wave of oscillation signal obtained according to wave of oscillation extraction unit
Press parameter value；
Linear control unit of inflating is used to controlling gas source module fingerstall or cuff is realized the first linear pattern and second linear of inflating
Inflate pattern, and air bag in pattern or the pressure change rate K in cuff are linearly inflated for setting first1With maximum pressure P1
And second linear air bag in pattern or the pressure change rate K in cuff of inflating2With maximum pressure P2Value；Wherein P1Less than P2；
The described first linear pattern of inflating is：After air bag or cuff inflation, the real-time pressure P in real-time collection air bag or cuff is simultaneously
Real-time pressure change rate K is calculated, using real-time pressure change rate K as PID control amount, by pressure change rate K1Become with real-time pressure
Rate K compares, and obtains the input quantity for controlling error as PID control, is less than P in P1Before, air pump is adjusted by PID in real time
Voltage U is to track pressure change rate K1, until realizing that the pressure in air bag or cuff linearly rises to P from 01；
The described second linear pattern of inflating is：By pressure change rate K2Compared with real-time pressure change rate K, obtain controlling error
As the input quantity of PID control, it is more than P in P1And less than P2Before, air pump voltage U is adjusted in real time by PID to track pressure change
Rate K2, up to realizing the pressure in air bag or cuff from P1Linearly rise to P2；When P is more than P2Afterwards, air bag or cuff stop filling
Gas；
The air pump voltage U is tried to achieve by following relational expression：
U=Kp*e+Ki* ∑ e+kd* Δs e
Wherein：Kp is proportional unit coefficient；Ki is integral unit coefficient；Kd is differentiation element coefficient；Δ e is the differential of error,
Equal to error current and the difference of preceding first-order error；
E is control error：E=K-Kn；KnFor K1Or K2；
K=Pi-P(i-1)；PiFor current collection point pressure value, P(i-1)For the pressure value of the previous collection point of current collection point.
2. survey meter of blood pressure as claimed in claim 1, it is characterised in that the wave of oscillation extraction unit is used for AD acquisition modules
Produced data signal is extracted, and final pressure wave of oscillation signal is obtained to analyze, and specific process is：
P is chosen first1Pressure waveform data above, passes it through 3Hz low pass software filtering, then intend by least square method
Conjunction obtains actual ramp signal, by P1Raw pressure signal above subtracts the ramp signal that fitting is obtained, and finally passes through again
0.5Hz software high-pass filtering, obtains final pressure wave of oscillation signal.
3. survey meter of blood pressure as claimed in claim 1, it is characterised in that the processor module also includes analysis of heart rate variability
Portion, the final pressure wave of oscillation signal of change for being obtained according to wave of oscillation extraction unit draws heart rate variability parameter value, and will
The heart rate variability parameter value calculated is compared with heart rate variability parameter value set in advance；If the heart rate calculated becomes
Different parameter value is more than the heart rate variability parameter value of setting, then starts blood pressure parameter calculating part, survey calculation pressure value；If calculating
The heart rate variability parameter value gone out is less than the heart rate variability parameter value of setting, then survey calculation heart rate variability parameter value always.
4. survey meter of blood pressure as claimed in claim 1, it is characterised in that also include：
Fingerstall valve module, for control fingerstall and main gas circuit connection whether, to control gas source module to the inflation/deflation of air bag, bag
Include fingerstall valve；
Cuff valve module, for control cuff and main gas circuit connection whether, to control gas source module to the inflation/deflation of cuff, bag
Include cuff valve；
Uniform valve module, for realizing uniform pressure release, including at the uniform velocity valve to the gas in air bag and cuff；
Rapid degassing valve module, for realizing quick pressure releasing, including rapid-release valve to air bag and cuff.
5. survey meter of blood pressure as claimed in claim 4, it is characterised in that the fingerstall valve, cuff valve, rapid-release valve and
Air pump is connected with four interfaces of the first four-way valve respectively；Fingerstall valve is also connected with an interface of triple valve, the threeway
Two other interface of valve is connected with fingerstall and cuff pressure sensor respectively；Cuff valve also connects with one of the second four-way valve
Mouth is connected, and the other three interface of second four-way valve is connected with the uniform velocity valve, cuff and cuff pressure sensor respectively.
6. the survey meter of blood pressure as described in claim 1 or 4, it is characterised in that the AD acquisition modules include one 24 50Hz
A/D converter.
7. the survey meter of blood pressure as described in claim 1 or 4, it is characterised in that also including user interactive module, in real time
Show detection information and receive user instruction；
Data transmission module, for carrying out data transmission with mobile terminal, realizes remote control.
8. the survey meter of blood pressure as described in claim 1 or 4, it is characterised in that also including acceleration sensor module, for carrying
For the 3-axis acceleration signal required for positioning user's posture and sleep state.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610389439.7A CN106108877B (en) | 2016-06-03 | 2016-06-03 | A kind of survey meter of blood pressure |
| PCT/CN2017/086341 WO2017206838A1 (en) | 2016-06-03 | 2017-05-27 | Blood pressure measurement instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610389439.7A CN106108877B (en) | 2016-06-03 | 2016-06-03 | A kind of survey meter of blood pressure |
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| CN106108877A CN106108877A (en) | 2016-11-16 |
| CN106108877B true CN106108877B (en) | 2017-09-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201610389439.7A Active CN106108877B (en) | 2016-06-03 | 2016-06-03 | A kind of survey meter of blood pressure |
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| WO (1) | WO2017206838A1 (en) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106108877B (en) * | 2016-06-03 | 2017-09-26 | 广州中科新知科技有限公司 | A kind of survey meter of blood pressure |
| WO2018168797A1 (en) * | 2017-03-15 | 2018-09-20 | オムロン株式会社 | Blood pressure measurement device, blood pressure measurement method, and program |
| CN107115110A (en) * | 2017-06-14 | 2017-09-01 | 陈畅 | A kind of type vibration wire survey meter of blood pressure |
| CN107692994A (en) * | 2017-09-04 | 2018-02-16 | 深圳市保身欣科技电子有限公司 | The double gas circuit blood pressure measuring devices of auto-manual based on intelligent mobile terminal |
| CN108703773B (en) * | 2018-06-07 | 2024-03-12 | 深圳市德力凯医疗设备股份有限公司 | Cerebral blood flow automatic regulating and monitoring device |
| CN108784742B (en) * | 2018-06-07 | 2024-03-12 | 深圳市德力凯医疗设备股份有限公司 | Cerebral blood flow automatic regulating and monitoring equipment |
| CN108742574B (en) * | 2018-06-07 | 2024-05-10 | 深圳市德力凯医疗设备股份有限公司 | Noninvasive continuous blood pressure measuring instrument |
| CN110025303A (en) * | 2019-04-17 | 2019-07-19 | 深圳大学 | A human blood pressure measuring device, method and system |
| CN112826468B (en) * | 2019-11-05 | 2023-12-01 | 深圳市大富智慧健康科技有限公司 | Blood pressure detection device, blood pressure detection system, and blood pressure monitoring method |
| CN113116322B (en) * | 2020-01-10 | 2024-06-25 | 深圳市理邦精密仪器股份有限公司 | Blood pressure measuring method and blood pressure measuring device |
| CN113520307B (en) * | 2020-04-20 | 2023-04-18 | 华为技术有限公司 | Wearable equipment |
| CN113520358A (en) * | 2020-04-21 | 2021-10-22 | 华为技术有限公司 | Blood pressure detection method and wearable device |
| CN112914530B (en) * | 2021-01-19 | 2024-06-04 | 深圳市迈泰生物医疗有限公司 | Automatic calibration type intelligent sphygmomanometer |
| CN113080910B (en) * | 2021-03-31 | 2024-05-17 | 广东乐心医疗电子股份有限公司 | Blood pressure measuring device and sphygmomanometer |
| CN113143238B (en) * | 2021-04-19 | 2022-07-12 | 研和智能科技(杭州)有限公司 | Blood pressure measuring device based on pressure signal and PPG signal |
| CN113712523B (en) * | 2021-09-01 | 2023-11-14 | 南京润楠医疗电子研究院有限公司 | System and method for rapidly and accurately determining servo reference value of volume compensation method |
| CN113729637A (en) * | 2021-09-29 | 2021-12-03 | 天津工业大学 | Fingerstall device for real-time air pressure tracking and air pressure tracking method |
| CN114259394B (en) * | 2021-12-13 | 2024-04-09 | 重庆邮电大学 | Pre-adaptive training system with comprehensive rehabilitation training strategy |
| TWI813432B (en) * | 2022-08-30 | 2023-08-21 | 豪展醫療科技股份有限公司 | Pressurization control method for blood pressure measurement and blood pressure machine using the pressurization control method |
| CN116649938B (en) * | 2023-07-31 | 2023-10-20 | 深圳市长坤科技有限公司 | Blood pressure measurement system based on bluetooth communication |
| CN117297571B (en) * | 2023-11-01 | 2024-04-05 | 广州逆熵电子科技有限公司 | Blood pressure measuring method of blood pressure watch and blood pressure watch |
| CN117942447A (en) * | 2024-03-27 | 2024-04-30 | 赤峰学院附属医院 | Defecation and bowel cleaning device |
| CN118648885A (en) * | 2024-06-18 | 2024-09-17 | 上海市高血压研究所 | Dynamic blood pressure monitoring system combining inflation and PTT measurement and its application method |
| CN119818045B (en) * | 2025-03-17 | 2025-05-13 | 新昌县天姥实验室 | Cuff blood pressure measuring method, system and device based on pressure sensing device |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2979933B2 (en) * | 1993-08-03 | 1999-11-22 | セイコーエプソン株式会社 | Pulse wave analyzer |
| US5590649A (en) * | 1994-04-15 | 1997-01-07 | Vital Insite, Inc. | Apparatus and method for measuring an induced perturbation to determine blood pressure |
| US20120238887A1 (en) * | 2001-02-26 | 2012-09-20 | Gerdt David W | Hydrostatic finger cuff for blood wave form analysis and diagnostic support |
| JP2003250770A (en) * | 2002-02-28 | 2003-09-09 | Omron Corp | Electronic sphygmomanometer |
| CN1507833A (en) * | 2002-12-16 | 2004-06-30 | 中国人民解放军空军航空医学研究所 | Integrated dynamic physiological parameter detecting and recording method and apparatus |
| CN100361625C (en) * | 2004-03-26 | 2008-01-16 | 香港中文大学 | non-invasive blood pressure measuring device and method |
| US20060195035A1 (en) * | 2005-02-28 | 2006-08-31 | Dehchuan Sun | Non-invasive radial artery blood pressure waveform measuring apparatus system and uses thereof |
| CN101612039B (en) * | 2009-07-28 | 2011-07-27 | 中国人民解放军第三军医大学野战外科研究所 | Self-adaption blood pressure detector |
| US20110152650A1 (en) * | 2009-12-21 | 2011-06-23 | General Electric Company | Adaptive pump control during non-invasive blood pressure measurement |
| JP5811766B2 (en) * | 2011-10-26 | 2015-11-11 | オムロンヘルスケア株式会社 | Electronic blood pressure monitor |
| CN202505340U (en) * | 2012-01-20 | 2012-10-31 | 亚弘电科技股份有限公司 | Multi-Balloon Sphygmomanometer |
| CN103349546A (en) * | 2013-07-16 | 2013-10-16 | 吕品 | Device and method for measuring pulse waves and blood pressures |
| CN203736185U (en) * | 2014-03-11 | 2014-07-30 | 天创聚合科技（上海）有限公司 | Blood pressure detecting device with function of cardiovascular function detection |
| CN104055499B (en) * | 2014-06-16 | 2016-06-22 | 朱宇东 | Monitor wearable Intelligent bracelet and the method for Human Physiology sign continuously |
| CN106108877B (en) * | 2016-06-03 | 2017-09-26 | 广州中科新知科技有限公司 | A kind of survey meter of blood pressure |
| CN205964031U (en) * | 2016-06-03 | 2017-02-22 | 广州中科新知科技有限公司 | Blood pressure measuring instrument |
-
2016
- 2016-06-03 CN CN201610389439.7A patent/CN106108877B/en active Active
-
2017
- 2017-05-27 WO PCT/CN2017/086341 patent/WO2017206838A1/en active Application Filing
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| WO2017206838A1 (en) | 2017-12-07 |
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Denomination of invention: Blood pressure measuring instrument Effective date of registration: 20190703 Granted publication date: 20170926 Pledgee: Bank of China, Limited by Share Ltd, Guangzhou, Panyu branch Pledgor: GUANGZHOU SENVIV TECHNOLOGY CO., LTD. Registration number: 2019440000250 |
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Denomination of invention: Blood pressure measuring instrument Effective date of registration: 20200409 Granted publication date: 20170926 Pledgee: Bank of China, Limited by Share Ltd, Guangzhou, Panyu branch Pledgor: GUANGZHOU SENVIV TECHNOLOGY Co.,Ltd. Registration number: Y2020440000073 |