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CN114245495A - Heating structure and medical nebulizer with solvent separation function - Google Patents

Heating structure and medical nebulizer with solvent separation function Download PDF

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Publication number
CN114245495A
CN114245495A CN202210034621.6A CN202210034621A CN114245495A CN 114245495 A CN114245495 A CN 114245495A CN 202210034621 A CN202210034621 A CN 202210034621A CN 114245495 A CN114245495 A CN 114245495A
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China
Prior art keywords
liquid medicine
heating
unit
units
separation function
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Pending
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CN202210034621.6A
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Chinese (zh)
Inventor
周孜聪
杜方楠
柴可
杜垚
邓晓琪
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Bulu Biotechnology Chengdu Co ltd
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Bulu Biotechnology Chengdu Co ltd
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Priority to CN202210034621.6A priority Critical patent/CN114245495A/en
Publication of CN114245495A publication Critical patent/CN114245495A/en
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    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05BELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B3/00Ohmic-resistance heating
    • H05B3/0033Heating devices using lamps
    • H05B3/0085Heating devices using lamps for medical applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • A61M11/044Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical with electrodes immersed in the liquid
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05BELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B3/00Ohmic-resistance heating
    • H05B3/02Details
    • H05B3/03Electrodes
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05BELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B3/00Ohmic-resistance heating
    • H05B3/10Heating elements characterised by the composition or nature of the materials or by the arrangement of the conductor
    • H05B3/12Heating elements characterised by the composition or nature of the materials or by the arrangement of the conductor characterised by the composition or nature of the conductive material
    • H05B3/14Heating elements characterised by the composition or nature of the materials or by the arrangement of the conductor characterised by the composition or nature of the conductive material the material being non-metallic
    • H05B3/145Carbon only, e.g. carbon black, graphite
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05BELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B3/00Ohmic-resistance heating
    • H05B3/20Heating elements having extended surface area substantially in a two-dimensional plane, e.g. plate-heater
    • H05B3/22Heating elements having extended surface area substantially in a two-dimensional plane, e.g. plate-heater non-flexible

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Resistance Heating (AREA)

Abstract

The application discloses heating structure and medical atomizer with solvent separation function, wherein, the heating structure with solvent separation function includes: the liquid medicine soaking units are used for soaking target liquid medicine, and are in a sheet shape; the heating units are used for heating the target liquid medicine to separate out a solvent of the target liquid medicine, the shape of each heating unit is matched with the liquid medicine soaking unit, and N is a positive integer; the heating units and the liquid medicine soaking units are arranged at intervals, and each heating unit is clamped between the two liquid medicine soaking units to form a liquid medicine absorber; a liquid medicine absorption unit for absorbing the target liquid medicine, the liquid medicine absorption unit being provided on the liquid medicine absorber; and a first electrode penetrating the chemical absorber and connecting the N heating units in parallel. This heating structure with solvent separation function has got rid of the solvent that influences the taste and can promote the taste of atomizing liquid medicine greatly, makes the patient have better taste and experiences.

Description

Heating structure with solvent separation function and medical atomizer
Technical Field
The application belongs to the technical field of medical equipment, concretely relates to heating structure and medical atomizer with solvent separation function.
Background
The atomizer is an important component for atomizing the solution, and the performance of the atomizer has a significant influence on the precision of measurement, chemical interference and the like. Therefore, the atomizer is required to have stable spraying, fine and uniform droplets, and high atomization efficiency. Atomizers are widely used in all industries. In the medical field, the atomizer can deliver the medicine to a deeper lesion position.
The existing atomizer is easy to destroy pharmacological components, and the atomized liquid medicine has poor taste.
Disclosure of Invention
The purpose of the present application is to provide a heating structure having a solvent separation function and a medical vaporizer that improve the taste of the atomized liquid medicine without destroying pharmacological components.
According to a first aspect of embodiments of the present application, there is provided a heat generating structure having a solvent separation function, which may include:
the device comprises N +1 liquid medicine soaking units, a liquid medicine soaking unit and a liquid medicine collecting unit, wherein the liquid medicine soaking units are used for soaking target liquid medicine and are in a sheet shape;
the heating units are used for heating the target liquid medicine to separate out a solvent of the target liquid medicine, the shape of each heating unit is matched with that of the liquid medicine soaking unit, and N is a positive integer;
the heating units and the liquid medicine soaking units are arranged at intervals, and each heating unit is clamped between two liquid medicine soaking units to form a liquid medicine absorber;
a liquid medicine absorption unit for absorbing the target liquid medicine, the liquid medicine absorption unit being provided on the liquid medicine absorber;
and a first electrode penetrating the chemical absorber, the first electrode being configured to connect the N heating units in parallel.
In some optional embodiments of the present application, the material of the liquid medicine infiltration unit and the material of the liquid medicine absorption unit are both porous ceramic materials.
In some optional embodiments of the present application, the liquid medicine infiltration unit and the adjacent heating unit are bonded by an adhesive.
In some optional embodiments of the present application, the heat generating unit includes:
two protective films;
the electrothermal layer is used for heating the target liquid medicine, is sheet-shaped, is provided with grooves at two ends close to the length direction of the electrothermal layer, and is clamped between the two protective films;
a second electrode disposed inside the groove;
and the fixing frame is arranged on the periphery of the protective film and used for fixing the protective film and the electric heating layer.
In some optional embodiments of the present application, the material of the protective film is PET, PEN, or PI.
In some optional embodiments of the present application, the material of the electrothermal layer is graphene or carbon crystal.
In some optional embodiments of the present application, the first electrode is a metal electrode and the second electrode is a silver electrode or a copper electrode.
In some optional embodiments of the present application, the material of the fixing frame is ceramic powder.
In some optional embodiments of the present application, an upper surface of the liquid medicine absorption unit is waved.
According to a second aspect of embodiments of the present application, there is provided a medical vaporizer, which may include: a heat generating structure having a solvent separating function as described in any one of the embodiments of the first aspect.
The technical scheme of the application has the following beneficial technical effects:
according to the structure of the embodiment of the application, the target liquid medicine is absorbed by the liquid medicine absorption unit, the liquid medicine soaks the target liquid medicine by the liquid medicine soaking unit, the absorbed target liquid medicine is heated by the heating unit, and the solvent of the target liquid medicine can be effectively separated by controlling the accurate temperature gradient of the heating unit without damaging pharmacological components. The solvent influencing the taste is removed, so that the taste of the atomized liquid medicine can be greatly improved, and the patient has better taste experience.
Drawings
Fig. 1 is a schematic structural view of a heat generating structure having a solvent separation function in an exemplary embodiment of the present application;
FIG. 2 is an exploded view of a heating structure with solvent separation in an exemplary embodiment of the present application;
FIG. 3 is an exploded view of a heat generating unit in an exemplary embodiment of the present application;
FIG. 4 is a schematic structural diagram of a heat generating unit in an exemplary embodiment of the present application;
fig. 5 is a thermal simulation diagram of a heat generating structure having a solvent separation function in an exemplary embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more apparent, the present application is further described in detail below with reference to the accompanying drawings in combination with the detailed description. It should be understood that the description is intended to be exemplary only, and is not intended to limit the scope of the present application. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present application.
In the drawings, a schematic diagram of a layer structure according to an embodiment of the application is shown. The figures are not drawn to scale, wherein certain details are exaggerated and possibly omitted for clarity. The shapes of various regions, layers, and relative sizes and positional relationships therebetween shown in the drawings are merely exemplary, and deviations may occur in practice due to manufacturing tolerances or technical limitations, and a person skilled in the art may additionally design regions/layers having different shapes, sizes, relative positions, as actually required.
It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
In the description of the present application, it is noted that the terms "first", "second", and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In addition, the technical features mentioned in the different embodiments of the present application described below may be combined with each other as long as they do not conflict with each other.
The heating structure and the medical vaporizer provided with the solvent separation function according to the embodiments of the present application will be described in detail with reference to the accompanying drawings.
As shown in fig. 1, in a first aspect of embodiments of the present application, there is provided a heat generating structure having a solvent separation function, which may include:
n +1 liquid medicine soaking units 3016, wherein the liquid medicine soaking unit 3016 is used for soaking the target liquid medicine, and the liquid medicine soaking unit 3016 is in a sheet shape;
n heating units 3015, where the heating units 3015 are configured to heat the target liquid medicine to separate a solvent of the target liquid medicine, the shape of the heating units 3015 is adapted to the liquid medicine infiltrating unit 3016, and N is a positive integer;
the heating units 3015 and the liquid medicine soaking units 3016 are arranged at intervals, and each heating unit 3015 is sandwiched between two liquid medicine soaking units 3016 to form a liquid medicine absorber;
a liquid medicine absorption unit 3017 for absorbing the target liquid medicine, the liquid medicine absorption unit 3017 being provided on the liquid medicine absorber;
and a first electrode 3019 penetrating through the liquid medicine absorber, the first electrode 3019 being configured to connect N of the heat generating units 3015 in parallel.
The above-described structure of the embodiment absorbs the target medical solution by the medical solution absorption unit 3017, soaks the target medical solution by the medical solution soakage unit 3016, and then heats the absorbed target medical solution by the heating unit 3015, and the solvent of the target medical solution can be effectively separated without damaging the pharmacological components by the precise temperature gradient control of the heating unit 3015. The solvent influencing the taste is removed, so that the taste of the atomized liquid medicine can be greatly improved, and the patient has better taste experience. As shown in fig. 2, a liquid medicine infiltrating unit 3016 and a liquid medicine absorbing unit 3017 of equal thickness are fired by porous ceramic powder, the liquid medicine infiltrating unit 3016 and the heating unit 3015 are arranged regularly at intervals, the liquid medicine absorbing unit 3017 is arranged above the arrangement of the liquid medicine infiltrating unit and the heating unit, and the functional components are fired into sheet units by LTCC low temperature co-firing technology and then fired into a whole. LTCC low temperature co-firing technology: the method is a technology for manufacturing low-temperature sintered ceramic powder into sheet units with accurate thickness and compactness, further processing different sheet units according to different functions, and sintering all the sheet units into an integral composite material.
In some optional embodiments of the present application, the chemical solution infiltration unit 3016 and the chemical solution absorption unit 3017 are both made of porous ceramic materials. Specifically, porous sinterable ceramic powder may be selected.
In some optional embodiments of the present application, the liquid medicine infiltrating unit 3016 is bonded to the adjacent heat generating unit 3015 by an adhesive. Specifically, a resin adhesive can be selected to improve the stability of the liquid medicine soaking unit 3016 and the heating unit 3015.
As shown in fig. 3, in some optional embodiments of the present application, the heat generating unit 3015 includes:
two protective films 3013;
the electric heating layer 3011 is used for heating the target liquid medicine, the electric heating layer 3011 is in a sheet shape, grooves are arranged at two ends of the electric heating layer 3011 in the length direction, and the electric heating layer 3011 is sandwiched between the two protective films 3013;
a second electrode 3012 disposed inside the groove;
and a fixing frame 3014 disposed on the periphery of the protective film 3013, wherein the fixing frame 3014 is used to fix the protective film 3013 and the electric heating layer 3011.
In the heating unit 3015, silver paste electrodes are formed on the material of the electrothermal layer 3011 by laser etching, grooving and pouring, and the silver paste electrodes are solidified and integrated with the electrothermal layer 3011. Wherein, laser etching: the high-energy pulse laser beam is adopted to etch a groove on the surface of a part, and is mostly applied to high-precision machining.
In the above embodiment, the first electrode 3019 may be installed by punching a hole in a CNC machining manner, punching two through holes, punching all the second electrodes 3012, and installing the first electrode 3019, an anode, and a cathode, so that all the heating units 3015 inside are connected in parallel and operate at the same power. CNC machining: conventional numerically controlled machining is used herein to drill holes in composite materials to incorporate electrodes. The above units are combined and put into a mould, and ceramic powder or glass powder is filled in the mould, and the mould is pressed and sintered into a whole, as shown in figure 4. And (3) mould pressing and sintering: filling the mold with a filling material, such as ceramic powder, and sintering under a certain pressure.
In some optional embodiments of the present application, the material of the protective film 3013 is PET, PEN, or PI. Because the material has good stability, insulativity and corrosion resistance, the heating unit and the liquid medicine soaking unit 3016 are separated, no leakage and short circuit risk exist, and the resin is harmless and corrosion resistant, thereby meeting the EMC and safety requirements of medical instruments.
In some optional embodiments of the present application, the material of the electrothermal layer 3011 is graphene or carbon crystal. Because the material is heated in a surface shape, the heat in the final composite material finished product is ensured to be uniformly distributed, and the temperature gradient is accurately controlled. The electrothermal layer 3011 is thin and has insufficient thermal stability, and needs a resin protective film 3013 for support.
In some optional embodiments of the present application, the first electrode 3019 is a metal electrode, and the second electrode 3012 is a silver electrode or a copper electrode.
In some optional embodiments of the present application, the fixing frame 3014 is made of ceramic powder.
In some optional embodiments of the present application, an upper surface of the liquid medicine absorption unit 3017 is waved. The wavy shape is to enlarge the contact area and increase the absorption efficiency.
As shown in fig. 5, it can be clearly seen from the cross-sectional and longitudinal sectional views of the thermal simulation that the liquid medicine reaches the bottom through the same temperature gradient regardless of which point of the liquid medicine absorption unit 3017 enters the heating structure with the solvent separation function of the present application. The heating structure with the solvent separation function realizes the accurate control of the heating gradient of the liquid medicine components. On the basis, the heating power of each heating unit 3015 can be controlled only by adjusting the total voltage on the composite material metal electrode.
In an alternative embodiment of the present application, the target medical solution is listed as follows, which is a composition table of herbal solution for throat discomfort, in which the alcohol content is 16.23%, and this herbal solution is represented as alcohol solvent type medical solution.
Figure BDA0003467805840000061
Figure BDA0003467805840000071
By searching the boiling points of all the components, the alcohol is 78.3 deg.C at the lowest, while the main pharmacological components in the herbal liquid have boiling points above 200 deg.C, and other solvents, such as glycerol, have boiling points of 290 deg.C. Aiming at the alcohol separation, the separation temperature is controlled between 80 ℃ and 100 ℃, so that the purpose of alcohol separation can be realized, and according to experimental experience, 95 ℃ is preferred. Aiming at the atomization of pharmacological components, the liquid medicine can be atomized only when the boiling point of other solvents after removing alcohol is at least reached, and the pharmacological components can be damaged when the temperature is too high. According to experimental experience, a temperature of 270 ℃ lower than the boiling point of glycerol by 20 ℃ is preferred to be sufficient for good atomization. The reason is that the application environment has a large airflow to generate negative pressure, and the glycerin can be fully atomized at 270 ℃.
Taking the herbal liquid as an example, the heating structure with the solvent separation function sets the corresponding electrifying power according to the technical parameters of the 95 ℃ separation alcohol temperature and the 270 ℃ atomization critical temperature. And programming the corresponding parameters into the MCU of the control system of the machine applied by the application so as to realize the functions. The heating structure with the solvent separation function can be adopted for carrying out power-on separation aiming at different liquid medicines or herbal liquids and aiming at solvent components with low boiling points.
The heating structure with the solvent separation function in the embodiment can realize accurate control of temperature gradient; the structural units are manufactured independently, and the integral composite material is formed by low-temperature co-firing, so that the optimal performance is kept; the alcohol solvent can be separated under the premise of not damaging pharmacological components due to the accurate solvent separation function; the heating unit 3015 and the liquid medicine soaking unit 3016 are separated, no leakage and short circuit risk exist, and resin is harmless and corrosion resistant, so that EMC and safety requirements of medical instruments are met.
According to a second aspect of embodiments of the present application, there is provided a medical vaporizer, which may include: a heat generating structure having a solvent separating function as described in any one of the embodiments of the first aspect.
While the present embodiments have been described with reference to the accompanying drawings, it is to be understood that the invention is not limited to the precise embodiments described above, which are meant to be illustrative and not restrictive, and that various changes may be made therein by those skilled in the art without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (10)

1. A heating structure having a solvent separation function, comprising:
n +1 liquid medicine soaking units (3016), wherein the liquid medicine soaking unit (3016) is used for soaking the target liquid medicine, and the liquid medicine soaking unit (3016) is in a sheet shape;
the heating units (3015) are used for heating the target liquid medicine to separate out a solvent of the target liquid medicine, the shape of the heating units (3015) is matched with that of the liquid medicine soaking unit (3016), and N is a positive integer;
the heating units (3015) and the liquid medicine soaking units (3016) are arranged at intervals, and each heating unit (3015) is arranged between two liquid medicine soaking units (3016) to form a liquid medicine absorber;
a liquid medicine absorbing unit (3017) for absorbing the target liquid medicine, the liquid medicine absorbing unit (3017) being provided on the liquid medicine absorber;
and a first electrode (3019) that penetrates the liquid medicine absorber, wherein the first electrode (3019) is used for connecting the N heating units (3015) in parallel.
2. The heating structure with the solvent separation function according to claim 1, wherein the material of the liquid medicine impregnating unit (3016) and the material of the liquid medicine absorbing unit (3017) are both porous ceramic materials.
3. The heating structure with the solvent separation function according to claim 1, wherein the liquid medicine impregnating unit (3016) and the adjacent heating unit (3015) are bonded by an adhesive.
4. The heat generating structure with solvent separating function according to claim 1, wherein the heat generating unit (3015) comprises:
two protective films (3013);
the electrothermal layer (3011) is used for heating the target liquid medicine, the electrothermal layer (3011) is in a sheet shape, grooves are arranged at two ends of the electrothermal layer (3011) in the length direction, and the electrothermal layer (3011) is clamped between the two protective films (3013);
a second electrode (3012) disposed inside the groove;
and the fixing frame (3014) is arranged on the periphery of the protective film (3013), and the fixing frame (3014) is used for fixing the protective film (3013) and the electric heating layer (3011).
5. The heating structure with solvent separation function according to claim 4, wherein the material of the protective film (3013) is PET, PEN or PI.
6. The heating structure with solvent separation function according to claim 4, wherein the material of the electrothermal layer (3011) is graphene or carbon crystal.
7. The heating structure with solvent separation function according to claim 4, wherein the first electrode (3019) is a metal electrode, and the second electrode (3012) is a silver electrode or a copper electrode.
8. The heating structure with the solvent separation function according to claim 4, wherein the material of the fixing frame (3014) is ceramic powder.
9. The heating structure with the solvent separation function according to claim 1, wherein an upper surface of the liquid medicine absorption unit (3017) is waved.
10. A medical vaporizer, comprising: a heat generating structure having a solvent separating function as claimed in any one of claims 1 to 9.
CN202210034621.6A 2022-01-13 2022-01-13 Heating structure and medical nebulizer with solvent separation function Pending CN114245495A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008058455A1 (en) * 2006-11-11 2008-05-22 Tafelberg International Limited Pulmonary medicament delivery device
CN208096022U (en) * 2018-04-03 2018-11-16 珠海惠友电子有限公司 A kind of Bidirectional heating component
US20200214361A1 (en) * 2019-01-05 2020-07-09 Shenzhen First Union Technology Co., Ltd. Atomizing core
CN112888093A (en) * 2021-01-13 2021-06-01 深圳麦克韦尔科技有限公司 Heating assembly, electronic atomization device and preparation method of heating assembly
CN214015964U (en) * 2020-10-14 2021-08-24 品度生物科技(深圳)有限公司 Liquid guide heating structure, atomization bin and atomizer
US20210345670A1 (en) * 2018-11-29 2021-11-11 Shenzhen First Union Technology Co., Ltd. Electronic cigarette atomizer and electronic cigarette comprising same

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008058455A1 (en) * 2006-11-11 2008-05-22 Tafelberg International Limited Pulmonary medicament delivery device
CN208096022U (en) * 2018-04-03 2018-11-16 珠海惠友电子有限公司 A kind of Bidirectional heating component
US20210345670A1 (en) * 2018-11-29 2021-11-11 Shenzhen First Union Technology Co., Ltd. Electronic cigarette atomizer and electronic cigarette comprising same
US20200214361A1 (en) * 2019-01-05 2020-07-09 Shenzhen First Union Technology Co., Ltd. Atomizing core
CN214015964U (en) * 2020-10-14 2021-08-24 品度生物科技(深圳)有限公司 Liquid guide heating structure, atomization bin and atomizer
CN112888093A (en) * 2021-01-13 2021-06-01 深圳麦克韦尔科技有限公司 Heating assembly, electronic atomization device and preparation method of heating assembly

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