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CN114085730A - 微流体细胞培养 - Google Patents

微流体细胞培养 Download PDF

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Publication number
CN114085730A
CN114085730A CN202110967507.4A CN202110967507A CN114085730A CN 114085730 A CN114085730 A CN 114085730A CN 202110967507 A CN202110967507 A CN 202110967507A CN 114085730 A CN114085730 A CN 114085730A
Authority
CN
China
Prior art keywords
microfluidic device
microfluidic
moiety
growth chamber
conditioned
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110967507.4A
Other languages
English (en)
Chinese (zh)
Inventor
R·D·小罗维
克丽诗汀·毕奥蒙特
阿蕯凡·卡卢那卡兰
娜塔莉·马克斯
J·M·麦克尤恩
M·P·怀特
J·坦纳·内维尔
王钢锋
安德鲁·W·麦克法兰
D·马莱奥
凯斯·J·布林格
关晓
凯文·T·查普曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Cellular Analysis Inc
Original Assignee
Berkeley Lights Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berkeley Lights Inc filed Critical Berkeley Lights Inc
Publication of CN114085730A publication Critical patent/CN114085730A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202110967507.4A 2015-04-22 2016-04-22 微流体细胞培养 Pending CN114085730A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562151325P 2015-04-22 2015-04-22
US62/151,325 2015-04-22
CN201680036332.2A CN107849505B (zh) 2015-04-22 2016-04-22 微流体细胞培养

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201680036332.2A Division CN107849505B (zh) 2015-04-22 2016-04-22 微流体细胞培养

Publications (1)

Publication Number Publication Date
CN114085730A true CN114085730A (zh) 2022-02-25

Family

ID=58055846

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202110967507.4A Pending CN114085730A (zh) 2015-04-22 2016-04-22 微流体细胞培养
CN201680036332.2A Active CN107849505B (zh) 2015-04-22 2016-04-22 微流体细胞培养

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201680036332.2A Active CN107849505B (zh) 2015-04-22 2016-04-22 微流体细胞培养

Country Status (4)

Country Link
EP (1) EP3286296A4 (de)
CN (2) CN114085730A (de)
HK (1) HK1253068A1 (de)
TW (2) TWI744230B (de)

Cited By (1)

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TWI832371B (zh) * 2022-08-10 2024-02-11 醫華生技股份有限公司 生物微粒培養設備及其微結構

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KR102547782B1 (ko) * 2017-01-31 2023-06-23 알피니티 유에스에이, 인크. 일체형 펌프를 갖는 바이오프로세스 용기
CN108485972B (zh) * 2018-03-28 2021-06-25 东南大学 一种用于细胞组织培养与实时监测的微流控芯片及其使用方法
AU2019301819B2 (en) * 2018-07-12 2023-01-12 Berkeley Lights, Inc. Screening plant protoplasts for disease resistant traits
CN116174068A (zh) 2019-04-30 2023-05-30 伯克利之光生命科技公司 用于包封和测定细胞的方法
CA3142449A1 (en) * 2019-06-20 2020-12-24 President And Fellows Of Harvard College Isolating live cells after high-throughput, long-term, time-lapse microscopy
CN114341341A (zh) * 2019-08-29 2022-04-12 发那科株式会社 细胞制造装置及其制造方法
JP7641280B2 (ja) * 2019-10-25 2025-03-06 バークレー ライツ，インコーポレイテッド マイクロ流体デバイスを作動させるためのシステム
JP7339138B2 (ja) * 2019-12-02 2023-09-05 株式会社日立製作所 細胞培養装置
TWI820630B (zh) * 2021-04-28 2023-11-01 友達光電股份有限公司 細胞操作面板、細胞分離裝置及執行細胞操作的方法
CN113996355B (zh) * 2021-10-28 2023-06-06 上海浚真生命科学有限公司 取样装置
US12252678B2 (en) 2021-12-01 2025-03-18 Microfluidx Ltd Systems and methods for bioprocessing
TWI859685B (zh) * 2022-12-30 2024-10-21 財團法人工業技術研究院 微流體結構、可攜式核酸檢測套組以及於戶外檢測樣本的核酸的方法
TWI849811B (zh) * 2023-03-21 2024-07-21 好孕行生醫股份有限公司 用以提供垂直溫差環境之加熱培養裝置及其使用方法
TWI848840B (zh) * 2023-10-25 2024-07-11 財團法人金屬工業研究發展中心 細胞改質系統及裝置
CN117262436B (zh) * 2023-11-21 2024-01-26 山东大学齐鲁医院 一种肿瘤切片存储装置

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US20140154703A1 (en) * 2011-01-06 2014-06-05 Alison Skelley Circulating tumor cell capture on a microfluidic chip incorporating both affinity and size
CN107257711A (zh) * 2014-12-05 2017-10-17 加利福尼亚大学董事会 具有集成网状地线的单面光致动微流体器件

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US20060154361A1 (en) * 2002-08-27 2006-07-13 Wikswo John P Bioreactors with substance injection capacity
US20060226012A1 (en) * 2005-04-08 2006-10-12 Kanagasabapathi Thirukumaran T Integrated microfluidic transport and sorting system
US20090137426A1 (en) * 2007-06-12 2009-05-28 Samsung Electronics Co., Ltd. Microarray, substrate for microarray and methods of fabricating the same
US20140154703A1 (en) * 2011-01-06 2014-06-05 Alison Skelley Circulating tumor cell capture on a microfluidic chip incorporating both affinity and size
US20120208266A1 (en) * 2011-02-11 2012-08-16 Dana Craig Bookbinder Enzyme cleavable cell release polymeric surface
CN107257711A (zh) * 2014-12-05 2017-10-17 加利福尼亚大学董事会 具有集成网状地线的单面光致动微流体器件

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI832371B (zh) * 2022-08-10 2024-02-11 醫華生技股份有限公司 生物微粒培養設備及其微結構

Also Published As

Publication number Publication date
CN107849505A (zh) 2018-03-27
TWI819383B (zh) 2023-10-21
HK1253068A1 (zh) 2019-06-06
TW201643241A (zh) 2016-12-16
TWI744230B (zh) 2021-11-01
TW202233824A (zh) 2022-09-01
EP3286296A1 (de) 2018-02-28
CN107849505B (zh) 2021-09-07
EP3286296A4 (de) 2019-01-09

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