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CN1140274C - Gu'anning ointment for treating hyperosteogeny and its prepn. method - Google Patents

Gu'anning ointment for treating hyperosteogeny and its prepn. method Download PDF

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Publication number
CN1140274C
CN1140274C CNB981105327A CN98110532A CN1140274C CN 1140274 C CN1140274 C CN 1140274C CN B981105327 A CNB981105327 A CN B981105327A CN 98110532 A CN98110532 A CN 98110532A CN 1140274 C CN1140274 C CN 1140274C
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radix
medicine
rhizoma
days
oil
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CN1213554A (en
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刘方明
赵升传
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Abstract

The present invention relates to a Chinese medicinal prescription of an external-use emplastrum, namely Gu'anning ointment for treating hyperosteogeny, and a preparation method thereof, which belongs to the technical field of medicine preparation and the preparation method thereof. The Gu'anning ointment having the functions of expelling wind, dissipating cold, promoting blood circulation to remove blood stasis, promoting qi circulation to relieve pain, and strengthening tendon and bone is prepared into black ointment by Chinese herbal medicinal materials of olibanum, myrrh, corydalis tuber, dragon's blood, manchurian wildginger, borneol and muskone in conventional technology according to a certain proportion. The Chinese medicinal prescription has conspicuous curative effect of treating hyperostosis and the symptoms such as the pain, the numbness and the swelling of the neck, the shoulders, the knees, the waist, the legs, etc. caused by hyperostosis and is convenient in use, carry and store.

Description

A kind of medicine for the treatment of hyperosteogeny and preparation method thereof
The present invention is a kind of Chinese medicine plaster for the treatment of hyperosteogeny disease, and this medicine belongs to the preparation and the preparation method technical field of Chinese medicine.
Hyperosteogeny is a series of degeneration of human body osteoarthrosis and surrounding soft tissue and the result of hypertrophy variation, usually with bony spur, hyperosteogeny, spinal canal stenosis, intervertebral disk hernia, ostealleosis, rheumatism involving the bone is commonly referred to as hyperosteogeny, the people is to after the middle age, osteoarthrosis and surrounding soft tissue thereof begin to degenerate and engender the hypertrophy phenomenon, peripheral vessels is oppressed at outgrowth position again, neural and around causing and the pain of region of interest tissue, numb swelling, joint motion is limited etc., all suffer from this sick people the lighter inconvenience of living, weight person's uneasy in either sitting or lying, sleeping and eating is not peaceful, some even permanent disbility, and treating this at present, sick to remove the massage physiotheraping effect be not very desirable, therefore, develops a kind of easy to use, curative effect is certain, cheap external preparation, fit and must go, CN1057965A discloses a kind of prescription and method for making thereof of Kezeng cream of external, and Kezeng cream has certain curative effect for hyperosteogeny, but his effect is not clearly, action time is short, easily recurrence, and price comparison is more expensive.
Purpose of the present invention just provides a kind of with low cost, and hyperosteogeny is had medicine of better therapeutical effect and preparation method thereof.Main contents of the present invention: this medicine is that raw material is made with the Chinese herbal medicine, and its constituent percentage by weight is as follows:
Radix Notoginseng 1.5-2% Rhizoma Chuanxiong 1.5-2% Radix Angelicae Dahuricae 1.5-2% Olibanum 1.5-1%
Myrrha 0.5-1% Semen Persicae 0.5-1% Rhizoma Corydalis 0.5-1% Flos Carthami 0.5-1%
Sanguis Draxonis 0.5-1% Borneolum Syntheticum 0.5-1% catechu 0.5-1% Herba Asari 0.5-1%
Cortex Cinnamomi 0.5-1% Rhizoma Et Radix Notopterygii 0.5-1% Radix Saposhnikoviae 0.5-1% Herba Schizonepetae 0.5-1%
Radix Clematidis 0.5-1% Fructus Psoraleae 0.5-1% Rhizoma Drynariae 1-1.5%
Radix Achyranthis Bidentatae 1-1.5% Radix Angelicae Sinensis 1-1.5% Radix Astragali 1-1.5%
Artificial Moschus 0.1-0.5% Oleum Sesami 50-60% Plumbum preparatium 20-30%.
Preparation method of the present invention comprises the steps:
1, soaks: medicine is weighed accurately by recipe quantity, except that Borneolum Syntheticum, artificial Moschus, get Radix Notoginseng, Olibanum, Myrrha, Sanguis Draxonis, catechu and be ground into fine powder, getting Oleum Sesami soaks medicines such as Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Semen Persicae, Rhizoma Corydalis, Flos Carthami, Radix Astragali, Rhizoma Drynariae, Herba Asari, Cortex Cinnamomi, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Herba Schizonepetae, Radix Clematidis, Fructus Psoraleae, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis in Oleum sesami, (steeped spring 5 days, soaked summer 2 days, soaked hot day 7 days, soaked winter 10 days).
2. the fried oil of getting it filled
It is withered and yellow that the medicine that soaked oil is heated to spice with slow fire earlier, and temperature is no more than 220 ℃, and is fried to the outside dark brown of spice, inner coke yellow, but not carbonization, blackening be advisable, from fire cold slightly remove slag, filter promptly get medicine oil.
3. oil refining
The heating of fluid after removing slag is tempered, and treats that refining can descend pellet when dripping into pearl.
4. pilling and pasting
At this moment otherwise stop stirring the good oil of refining is added the Plumbum preparatium,, in case the heavy poly-the bottom of a pan of red powder emits to the greatest extent to white cigarette, medicine oil is taken out during for pitchy by brown stain and splashes on a small quantity in the cold water, takes out after the several seconds, and the tack-free denseness of ointment is suitable.
5. releasing fire-toxin
After plaster was boiled into, impouring was got ready in the cold water and is constantly stirred, and should change cold water in addition when the water heating, and the back of condensing is taken out and pinched pressure repeatedly, and makes agglomerate, is dipped in the cold water, changes water every day one time, soaks (15 days winters, 5 days summers) 7.
6. mix the fines medicine
Get the plaster agglomerate and put in the container, in water-bath, dissolve, make temperature in the time of 60~70 ℃, mix into fines medicines such as Radix Notoginseng, Olibanum, Myrrha, Sanguis Draxonis, catechu, Borneolum Syntheticum, stir evenly.
7. the stand is coated with
Take by weighing the plaster of constant weight, spread out in paper or cloth etc. and mount on the backing material,, the artificial Moschus is spread on the plaster surface can collects standby.
The present invention is that raw material is made with the Chinese herbal medicine, we's Radix Angelicae Dahuricae at first for this reason, Herba Asari, Radix Saposhnikoviae, Herba Schizonepetae, Radix Clematidis, Cortex Cinnamomis etc. win wet with expelling wind and cold, again with Rhizoma Chuanxiong, Olibanum, Myrrha, Semen Persicae, Flos Carthami, Radix Achyranthis Bidentatae, Radix Notoginseng, the product blood circulation promoting and blood stasis dispelling of Sanguis Draxonis, detumescence relieves the pain, qi being the governor of blood, the capable then blood of gas is capable, eliminate as early as possible in order to make local pain caused by ecchymoma, join Rhizoma Corydalis in the event side again, Borneolum Syntheticum, the promoting the circulation of QI to relieve pain of having one's ideas straightened out such as Herba Asari, numbness for a long time must be empty, must nourishing liver and kidney, benefiting QI and nourishing blood, so just again with Rhizoma Drynariae, Fructus Psoraleae, Radix Angelicae Sinensis, nourishing the liver and kidney such as the Radix Astragali, strong muscles and bones, benefiting QI and nourishing blood, catechu is antipruritic with its convergence, and its counteracting toxic substances is mainly used in the Plumbum preparatium in the side, removing dampness is antipruritic, is the excipient of plaster simultaneously.
The medicine of full side is auxilliary mutually to be usefulness, giving consideration to both the incidental and fundamental, and eliminating evil is main, and does not hinder healthy energy, setting upright is to help, and does not stay heresy, and it has expelling wind and cold, blood circulation promoting and blood stasis dispelling, circulation of qi promoting relieve the pain, the effect of bone and muscle strengthening, and reaching the bones and muscles pain and the rheumatic Bi syndrome that cause thus for hyperosteogeny has better curative effect.This medicine is through Hospital Affiliated to Shandong Medical College's clinical observation, the preclinical pharmacology experiment confirm, this medicine has good antiinflammation to acute exudative inflammation, chronic hyperplastic inflammation also had remarkable antagonism, and the painful effect in significant non-specific town is arranged, test by microcirculation improvement, the result as can be seen, this medicine has good antagonism pituitrin and causes the microcirculation disturbance effect, capacity of returns slip in the time of can obviously reducing microcirculation disturbance, this effect of this medicine is one of mechanism of the painful effect in its antiinflammatory town, also from certain angle illustrated compound Chinese medicinal preparation the effect of unique characteristics.The total effective rate that this group is treated two courses of treatment reaches 100%, and curative effect is extremely remarkable, and to cervical spondylosis, hyperosteogeny, three kinds of various disease of intervertebral disk hernia all obtain good therapeutic effect.The effective percentage for the treatment of two courses of treatment illustrates with administration time to prolong that than significantly improving a course of treatment curative effect of this medicine also strengthens, after finishing for second course of treatment, patient's sings and symptoms be improved significantly, all symptoms have 49.7% to disappear, 42.7% alleviates, 7.6% no change is only arranged, illustrate that this medicine has remarkable blood circulation promoting and blood stasis dispelling, bone and muscle strengthening, expelling cold and dampness, the analgesic effect of regulating the flow of vital energy, it is short that we observe the course of disease, and the patient treatment that symptom is lighter is effective.
Toxicological study is found before clinical, this medicine can not produce acute toxic reaction because of contact absorbs to the animal of complete and imperfect skin, skin is had no stimulation, only minimum several animals there is the mild skin anaphylaxis, very fast alleviation after the drug withdrawal, do not have other untoward reaction, illustrate that this clinical drug application safety is reliable.
The present invention has that raw material is extensive, and cost is low, craft science, and constant product quality, effect is lasting, and is easy to use, good effect.This medicine can be used as the at first medicine of treatment hyperosteogeny disease.
Embodiment: manufacture method:
1, soak: medicine is weighed accurately by recipe quantity, except that Borneolum Syntheticum 200g artificial Moschus 100g, get Radix Notoginseng 500g, Olibanum 300g, Myrrha 300g, Sanguis Draxonis 300g, catechu 200g, be ground into fine powder, with Rhizoma Chuanxiong 500g, Radix Angelicae Dahuricae 500g, Semen Persicae 300g, Rhizoma Corydalis 300g, Flos Carthami 300g, Radix Astragali 400g, Rhizoma Drynariae 400g, Herba Asari 200g, Cortex Cinnamomi 300g, Rhizoma Et Radix Notopterygii 300g, Radix Saposhnikoviae 300g, Herba Schizonepetae 300g, Radix Clematidis 300g, Fructus Psoraleae 400g, Radix Achyranthis Bidentatae 400g, Radix Angelicae Sinensis 400g, soak in Oleum Sesami 18000g Deng medicine, (steeped spring 5 days, soaked summer 2 days, soaked autumn 7 days, soaked winter 10 days).
2, the fried oil of getting it filled
It is withered and yellow that the medicine that soaked oil is heated to spice with slow fire earlier, and temperature is no more than 220 ℃, and is fried to the outside dark brown of spice, inner coke yellow, but not carbonization, blackening be advisable, from fire cold slightly remove slag, filter promptly get medicine oil.
3. oil refining
The heating of fluid after removing slag is tempered, and treats that refining can descend pellet when dripping into pearl.
4. pilling and pasting
At this moment otherwise stop stirring the good medicine oil of refining is added Plumbum preparatium 7200g,, in case the heavy poly-the bottom of a pan of red powder, emit to the greatest extent to white cigarette, medicine oil is taken out during for pitchy by brown stain and splashes on a small quantity in the cold water, takes out after the several seconds, if cream is tack-free thick useless suitable.
5. releasing fire-toxin
After plaster was boiled into, impouring was got ready in the cold water and is constantly stirred, and should change cold water in addition when the water heating, and the back of condensing is taken out and pinched pressure repeatedly, and makes agglomerate, is dipped in the cold water, changes water every day one time, soaks (15 days winters, 5 days summers) 7.
6. mix the fines medicine
Get the plaster agglomerate and put in the container, in water-bath, dissolve, make temperature in the time of 60~70 ℃, mix into fines medicines such as Radix Notoginseng 500g, Olibanum 300g, Myrrha 300g, Sanguis Draxonis 300g, catechu 200g, Borneolum Syntheticum 200g, stir evenly.
7. the stand is coated with
Take by weighing the plaster of constant weight, spread out in paper or cloth etc. and mount on the backing material,, artificial Moschus 100g evenly is spread on the plaster surface can collects standby.

Claims (4)

1, a kind of medicine for the treatment of hyperosteogeny disease is characterized in that this medicine is that raw material is made with the Chinese herbal medicine, and its raw material percentage composition is as follows:
Radix Notoginseng 1.5-2% Rhizoma Chuanxiong 1.5-2% Radix Angelicae Dahuricae 1.5-2% Olibanum 1.5-1%
Myrrha 0.5-1% Semen Persicae 0.5-1% Rhizoma Corydalis 0.5-1% Flos Carthami 0.5-1%
Sanguis Draxonis 0.5-1% Borneolum Syntheticum 0.5-1% catechu 0.5-1% Herba Asari 0.5-1%
Cortex Cinnamomi 0.5-1% Rhizoma Et Radix Notopterygii 0.5-1% Radix Saposhnikoviae 0.5-1% Herba Schizonepetae 0.5-1%
Radix Clematidis 0.5-1% Fructus Psoraleae 0.5-1% Rhizoma Drynariae 1-1.5%
Radix Achyranthis Bidentatae 1-1.5% Radix Angelicae Sinensis 1-1.5% Radix Astragali 1-1.5%
Artificial Moschus 0.1-0.5% Oleum Sesami 50-60% Plumbum preparatium 20-30%.
2, wherein the percentage by weight of each raw material is as follows for the medicine of treatment hyperosteogeny according to claim 1:
Radix Notoginseng 1.5% Rhizoma Chuanxiong 1.5% Radix Angelicae Dahuricae 1.5% Olibanum 0.9% Myrrha 0.9%
Semen Persicae 0.9% Rhizoma Corydalis 0.9% Flos Carthami 0.9% Sanguis Draxonis 0.9% Borneolum Syntheticum 0.6%
Catechu 0.6% Herba Asari 0.6% Cortex Cinnamomi 0.9% Rhizoma Et Radix Notopterygii 0.9% Radix Saposhnikoviae 0.9%
Herba Schizonepetae 0.9% Radix Clematidis 0.9% Fructus Psoraleae 1.3% Rhizoma Drynariae 1.3%
Radix Achyranthis Bidentatae 1.3% Radix Angelicae Sinensis 1.3% Radix Astragali 1.3% artificial Moschus 0.3%
Oleum Sesami 55% Plumbum preparatium 22%.
3,, it is characterized in that said medicament is a said black plaster dosage form on the pharmaceutics according to the medicine of the described treatment hyperosteogeny of one of right 1-2.
4,, it is characterized in that preparation method of the present invention comprises the steps: according to the preparation method of right 3 described treatment hyperosteogeny medicines
(1), soaks: medicine is weighed accurately by recipe quantity, except that Borneolum Syntheticum, artificial Moschus, get Radix Notoginseng, Olibanum, Myrrha, Sanguis Draxonis, catechu and be ground into fine powder, medicines such as Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Semen Persicae, Rhizoma Corydalis, Flos Carthami, Radix Astragali, Rhizoma Drynariae, Herba Asari, Cortex Cinnamomi, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Herba Schizonepetae, Radix Clematidis, Fructus Psoraleae, Radix Achyranthis Bidentatae, Radix Angelicae Sinensis are soaked in Oleum Sesami, steeped spring 5 days, soaked summer 2 days, soaked hot day 7 days, soaked winter 10 days.
(2) the fried oil of getting it filled
It is withered and yellow that the medicine that soaked oil is heated to spice with slow fire earlier, and temperature is no more than 220 ℃, and is fried to the outside dark brown of spice, and inner coke yellow, but not carbonization, blackening be advisable removes slag from fire is cold slightly, filters and promptly gets medicine oil.
(3) oil refining
The heating of fluid after removing slag is tempered, and treats that refining can descend pellet when dripping into pearl.
(4) pilling and pasting
At this moment otherwise stop stirring the good oil of refining is added the Plumbum preparatium,, in case the heavy poly-the bottom of a pan of red powder emits to the greatest extent to white cigarette, medicine oil is taken out during for pitchy by brown stain and splashes on a small quantity in the cold water, takes out after the several seconds, and the tack-free denseness of ointment is suitable.
(5) releasing fire-toxin
After plaster was boiled into, impouring was got ready in the cold water and is constantly stirred, and should change cold water in addition when the water heating, and the back of condensing is taken out and pinched pressure repeatedly, and makes agglomerate, is dipped in the cold water, changes water every day one time, soaks 15 days winters, 5 days summers 7.
(6) mix the fines medicine
Get the plaster agglomerate and put in the container, in water-bath, dissolve, make temperature in the time of 60~70 ℃, mix into fines medicines such as Radix Notoginseng, Olibanum, Myrrha, Sanguis Draxonis, catechu, Borneolum Syntheticum, stir evenly.
(7) stand is coated with
Take by weighing the plaster of constant weight, spread out in paper or cloth etc. and mount on the backing material,, the artificial Moschus is spread on the plaster surface can collects standby.
CNB981105327A 1998-10-28 1998-10-28 Gu'anning ointment for treating hyperosteogeny and its prepn. method Expired - Fee Related CN1140274C (en)

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Application Number Priority Date Filing Date Title
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CN1140274C true CN1140274C (en) 2004-03-03

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1943635B (en) * 2006-10-27 2010-04-21 王德振 Chinese traditional medicinal preparation for treating bone injuries and osteonosus

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001091769A2 (en) * 2000-06-01 2001-12-06 Theralife, Inc. Compositions for enhancing therapeutic effects containing herbals and/or nutritional supplements and/or minerals and/or vitamins
CN102920874B (en) * 2012-11-19 2014-03-12 刘方明 Medicinal paste for treating infection
CN107412622A (en) * 2017-08-24 2017-12-01 李永富 A kind of ointment for rheumatic spur and its preparation method and application
CN109419926A (en) * 2017-08-29 2019-03-05 河北万岁药业有限公司 Wheeling spur treats cream and its preparation process
CN112603958B (en) * 2021-01-12 2022-01-04 南方医科大学 A kind of traditional Chinese medicine composition for treating myofasculitis, preparation method and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1943635B (en) * 2006-10-27 2010-04-21 王德振 Chinese traditional medicinal preparation for treating bone injuries and osteonosus

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