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CN113350212A - Natural brightening essence and preparation method thereof - Google Patents

Natural brightening essence and preparation method thereof Download PDF

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Publication number
CN113350212A
CN113350212A CN202110812622.4A CN202110812622A CN113350212A CN 113350212 A CN113350212 A CN 113350212A CN 202110812622 A CN202110812622 A CN 202110812622A CN 113350212 A CN113350212 A CN 113350212A
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parts
skin
natural
essence
agent
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Inventor
张立强
其他发明人请求不公开姓名
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Guangzhou Xinzhuang Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26Optical properties
    • A61K2800/262Transparent; Translucent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48Thickener, Thickening system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52Stabilizers
    • A61K2800/524Preservatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention belongs to the technical field of cosmetics and discloses natural brightening essence and a preparation method thereof. The essence is in a slightly sticky and transparent liquid product system mode, can promote absorption efficiency of various raw materials and effective components in a product while ensuring sufficient moisturizing effect and maintenance effect, enhances whitening function and skin brightening function, and further achieves the effects of fine and smooth skin moistening, deep moisturizing, damaged cutin repairing, skin elasticity, skin whitening and skin brightening, color spot removing, color spot whitening, skin tightening and brightening, and water moistening and luster. The natural brightening essence is rich in natural whitening agents and various plant extract essential oils, and further improves the whitening effect of the product. The product is regulated by pH value and blended to obtain the maintenance essence most suitable for national skin. The essence does not contain any chemical components, has no side effect, and has high safety.

Description

Natural brightening essence and preparation method thereof
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to natural transparent essence and a preparation method thereof.
Background
The skin is the largest and most easily seen organ of the body and is also the natural barrier of the human body. It can not only reflect the health level of human body, but also reflect the concrete embodiment of "external beauty" of human body. "it is everyone who likes beauty", people have a continuous pursuit for beautifying their own cosmetics since ancient times. Conventional cosmetics are mainly used for skin care, skin cleansing and improvement of skin softness by virtue of their nutritional ingredients and moisture retention ingredients. With the change of living environment and the improvement of living standard of people, the skin care product with special effects such as whitening, anti-wrinkle and dark eye circle removal becomes a hot spot of personal care product industry. And the whitening products are more popular with consumers.
The basal layer cells of the human epidermis contain 4-5% of pigment cells, wherein melanin is a key factor determining the skin color and is also a main reason causing the skin color change. Two different types of melanin also have an effect on the color of the skin. Eumelanin is black or brown in color and is synthesized by tyrosinase. Pheomelanin is orange and is synthesized from tyrosine and cysteine.
The main means of whitening is to inhibit the generation of melanin and interfere the formation and transfer process of melanin. Within melanocytes, including the selective destruction of melanocytes and inhibition of tyrosinase activity; outside of the melanocyte includes interference with transfer of melanosomes, increased degradation of melanin in the keratin cell, and the like. Some substituted phenolic compounds such as hydroxyanisole, hydroquinone, resorcinol, arbutin and the like show specific toxicity to melanocytes; the mercury salt and some protein denaturants have an inhibitory effect on tyrosinase; ascorbic acid has reducing effect, and can prevent dopa generated by tyrosine under tyrosinase catalysis from being oxidized into dopaquinone.
There are many whitening products on the market at present. But the safety and effectiveness of each product are not uniform. Some whitening products have quick response, such as 'a whitening mask', and actually various prohibited components such as dexamethasone, beclomethasone, mercury, hydroquinone and the like are added in most of the products, so that health of consumers is endangered after the products are used. Some approved whitening agents, such as niacinamide, salicylic acid, vitamin C, kojic acid, etc., also cause irritation to the skin. Meanwhile, many products have insufficient moisturizing function, moistening function, maintenance function and whitening function.
At present, the whitening, moisturizing and moisturizing effects of the product are more obvious, and the reason for melanin formation must be comprehensively considered. Therefore, the whitening product with multiple functions, stability and safety is selected to play the role of synergistic whitening, and the whitening product has important significance.
Disclosure of Invention
In order to solve the problems in the prior art, the invention aims to provide a natural brightening essence and a preparation method thereof.
The technical scheme adopted by the invention is as follows: the natural transparent essence is mainly prepared from the following raw materials in parts by mass:
5-14 parts of allantoin, 1-42 parts of thickening agent, 1-10 parts of preservative, 10-136 parts of humectant, 1-27 parts of skin conditioner, 1-3 parts of chelating agent, 1-20 parts of emulsifier, 1-60 parts of skin softener, 1-5 parts of flavoring agent and 1-10 parts of solubilizer.
Preferably, the essence is mainly prepared from the following raw materials in parts by mass:
7-12 parts of allantoin, 5-35 parts of thickening agent, 2-8 parts of preservative, 50-110 parts of humectant, 5-22 parts of skin conditioner, 1.5-2.8 parts of chelating agent, 4-16 parts of emulsifier, 12-48 parts of skin softener, 2-4 parts of flavoring agent and 2-8 parts of solubilizer.
Preferably, the essence is mainly prepared from the following raw materials in parts by mass:
10 parts of allantoin, 30 parts of thickening agent, 6 parts of preservative, 80 parts of humectant, 18 parts of skin conditioner, 2 parts of chelating agent, 12 parts of emulsifier, 36 parts of skin emollient, 3 parts of flavoring agent and 6 parts of solubilizer.
Preferably, the thickener is a carbomer;
the preservative is methyl hydroxybenzoate;
the humectant is propylene glycol and/or niacinamide.
Preferably, the skin conditioning agent is sodium hyaluronate and/or hyaluronic acid;
the chelating agent is EDTA disodium;
the emulsifier is phenoxyethanol.
Preferably, the skin emollient comprises one or more of caprylhydroxamic acid, caprylate, ethylhexylglycerin, propylene glycol, and butylene glycol.
Preferably, the odorant is a floral essential oil; the floral essential oil includes, but is not limited to, one or more of lily essential oil, gentian essential oil, saffron essential oil and saussurea involucrate essential oil.
Preferably, the solubilizer is CO-40 and/or PEG-40.
A method for preparing natural transparent essence comprises selecting allantoin, thickener, humectant, skin conditioner, chelating agent, emulsifier, skin emollient, flavoring agent, solubilizer and solvent according to corresponding proportion, mixing, adding antiseptic and acid-base regulator, and mixing to obtain the final product.
Preferably, the solvent is water;
the acid-base regulator is potassium hydroxide solution; adjusting the pH value to 5-7 by the acid and the alkali;
the total volume ratio of the solvent to the allantoin, the thickening agent, the humectant, the skin conditioning agent, the chelating agent, the emulsifier, the skin emollient, the flavoring agent and the solubilizer is 2-5: 1.
The invention has the beneficial effects that:
the invention provides a natural brightening essence which is in a slightly-sticky and transparent liquid product system mode, can promote absorption efficiency of various raw materials and effective components in a product while ensuring sufficient moisturizing effect and maintenance effect, and enhances whitening function and skin brightening function, so as to achieve the effects of smoothing and moistening skin, deeply moisturizing, repairing damaged cutin, making skin elastic and smooth, whitening and brightening skin color, removing color spots, whitening, compacting and brightening, and moisturizing and moistening luster.
The natural brightening essence is rich in natural whitening agents and various plant extract essential oils, and further improves the whitening effect of the product. The product is regulated by pH value and blended to obtain the maintenance essence most suitable for national skin. The essence does not contain any chemical components, has no side effect, and has high safety.
Detailed Description
The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. The reagents used are all conventional products which are commercially available.
Example 1:
a preparation method of natural transparent essence comprises the steps of selecting 5 g of allantoin, 1 g of carbomer, 10 g of propylene glycol, 1 g of sodium hyaluronate, 1 g of EDTA disodium, 1 g of phenoxyethanol, 1 g of ethylhexyl glycerol, 1 g of lily essential oil, CO-401 g and 44 g of water according to corresponding proportion, mixing, adding 1 g of methylparaben and sodium hydroxide solution to adjust the pH value to 5-7, and uniformly mixing to obtain a finished product.
Example 2:
a preparation method of a natural transparent essence comprises the steps of selecting 14 g of allantoin, 42 g of carbomer, 136 g of nicotinamide, 27 g of hyaluronic acid, 3 g of disodium EDTA, 20 g of phenoxyethanol, 60 g of caprylyl hydroxamic acid, 5 g of gentian essential oil, PEG-4010 g and 1585 g of water according to corresponding proportion, mixing, adding 10 g of methylparaben and a sodium hydroxide solution, adjusting the pH value to 5-7, and uniformly mixing to obtain a finished product.
Example 3:
a preparation method of natural transparent essence comprises the steps of selecting 7 g of allantoin, 5 g of carbomer, 50 g of propylene glycol, 5 g of sodium hyaluronate, 1.5 g of EDTA disodium, 4 g of phenoxyethanol, 12 g of glyceryl caprylate, 2 g of saffron crocus essential oil, CO-402 g and 177 g of water according to corresponding proportion, mixing, adding 2 g of methylparaben and sodium hydroxide solution to adjust the pH value to 5-7, and uniformly mixing to obtain a finished product.
Example 4:
a preparation method of a natural brightening essence comprises the steps of selecting 12 g of allantoin, 35 g of carbomer, 110 g of nicotinamide, 22 g of hyaluronic acid, 2.8 g of disodium EDTA, 16 g of phenoxyethanol, 48 g of butanediol, 4 g of saussurea involucrate essential oil, PEG-408 g and 1289 g of water according to corresponding proportion, mixing, adding 8 g of methylparaben and sodium hydroxide solution, adjusting the pH value to 5-7, and uniformly mixing to obtain a finished product.
Example 5:
a preparation method of a natural transparent essence comprises the steps of selecting 10 g of allantoin, 30 g of carbomer, 80 g of propylene glycol, 18 g of sodium hyaluronate, 2 g of EDTA disodium, 12 g of phenoxyethanol, 36 g of caprylyl hydroxamic acid, 3 g of lily essential oil, CO-406 g and 985 g of water according to corresponding proportion, mixing, adding 6 g of methylparaben and sodium hydroxide solution to adjust the pH value to 5-7, and uniformly mixing to obtain a finished product.
Examples of the experiments
And (4) testing the moisture retention degree: the test principle is as follows: the water content of the horny layer of the human skin is tested by a capacitance method by using a human skin tester. The moisturizing ability of the product was evaluated by measuring the change in the water content of the stratum corneum of the skin before and after the use of the product in example 5 by volunteers.
Experimental example: the product obtained in example 5; control group: certain small bulb whitening essence is sold in the market. The lower jaw part is used as a blank control group, and the blank control group is not coated with any skin care product.
The test method comprises the following steps: selecting 30 volunteers, cleaning face with the same facial cleanser between 20-35 years of age, and smearing the experimental example and the control group products on two sides of the cheek respectively, wherein the smearing amount is kept consistent. The moisture content of the volunteers before and after use is tested by a human skin tester, and the moisture retention performance of the product is evaluated by taking the average value.
Figure BDA0003168997140000051
Figure BDA0003168997140000061
As can be seen from the above table, the product prepared in example 5 can significantly increase the moisture content of the skin, and has long moisturizing time and low moisture loss rate.
Cosmetic safety testing:
the skin irritation test was performed on the products prepared in all the above examples, and the skin irritation results were evaluated according to the skin irritation test of "technical standards for safety of cosmetics" 2015 edition:
item detection time point 24h 48h 72h Degree of irritation
Example 1 0 0 0 Has no irritation
Example 2 0 0 0 Has no irritation
Example 3 0 0 0 Has no irritation
Example 4 0 0 0 Has no irritation
Example 5 0 0 0 Has no irritation
As can be seen from the above table, the products prepared by using all the above examples have no irritation, have no obvious difference and meet the national standard.
The present invention is not limited to the above alternative embodiments, and any other products in various forms can be obtained by the present invention, and the present invention is within the protection scope of the present invention. The above embodiments should not be construed as limiting the scope of the present invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the above embodiments, or equivalent substitutions may be made to some or all of the technical features thereof, without departing from the scope of the present invention, and at the same time, such modifications or substitutions may not make the essence of the corresponding technical solutions depart from the scope of the embodiments of the present invention.

Claims (10)

1. The natural transparent essence is characterized by being prepared from the following raw materials in parts by mass:
5-14 parts of allantoin, 1-42 parts of thickening agent, 1-10 parts of preservative, 10-136 parts of humectant, 1-27 parts of skin conditioner, 1-3 parts of chelating agent, 1-20 parts of emulsifier, 1-60 parts of skin softener, 1-5 parts of flavoring agent and 1-10 parts of solubilizer.
2. The natural transparent essence according to claim 1, wherein the essence is mainly prepared from the following raw materials in parts by mass:
7-12 parts of allantoin, 5-35 parts of thickening agent, 2-8 parts of preservative, 50-110 parts of humectant, 5-22 parts of skin conditioner, 1.5-2.8 parts of chelating agent, 4-16 parts of emulsifier, 12-48 parts of skin softener, 2-4 parts of flavoring agent and 2-8 parts of solubilizer.
3. The natural transparent essence liquid as claimed in claim 2, which is prepared from the following raw materials in parts by mass:
10 parts of allantoin, 30 parts of thickening agent, 6 parts of preservative, 80 parts of humectant, 18 parts of skin conditioner, 2 parts of chelating agent, 12 parts of emulsifier, 36 parts of skin emollient, 3 parts of flavoring agent and 6 parts of solubilizer.
4. A natural lightening essence according to any one of claims 1 to 3 wherein the thickening agent is carbomer;
the preservative is methyl hydroxybenzoate;
the humectant is propylene glycol and/or niacinamide.
5. A natural lightening essence according to any one of claims 1 to 3 wherein the skin conditioning agent is sodium hyaluronate and/or hyaluronic acid;
the chelating agent is EDTA disodium;
the emulsifier is phenoxyethanol.
6. A natural lightening essence according to any one of claims 1 to 3 wherein the skin emollient comprises one or more of caprylyl hydroxamic acid, caprylic acid, ethylhexyl glycerin, propylene glycol and butylene glycol.
7. A natural lightening essence according to any one of claims 1 to 3, wherein the flavoring agent is a flower essential oil; the flower essential oil comprises one or more of lily essential oil, gentian essential oil, saffron essential oil and saussurea involucrate essential oil.
8. A natural lightening essence according to any one of claims 1 to 3 wherein the solubilizing agent is CO-40 and/or PEG-40.
9. A method for preparing a natural transparent essence according to any one of claims 1 to 8, wherein the natural transparent essence is prepared by mixing allantoin, a thickening agent, a humectant, a skin conditioner, a chelating agent, an emulsifier, a skin emollient, a flavoring agent, a solubilizer and a solvent according to a corresponding ratio, adding a preservative and an acid-base regulator, and uniformly mixing to obtain a finished product.
10. The method of claim 9, wherein the solvent is water;
the acid-base regulator is potassium hydroxide solution; adjusting the pH value to 5-7 by the acid and the alkali;
the total volume ratio of the solvent to the allantoin, the thickening agent, the humectant, the skin conditioning agent, the chelating agent, the emulsifier, the skin emollient, the flavoring agent and the solubilizer is 2-5: 1.
CN202110812622.4A 2021-07-19 2021-07-19 Natural brightening essence and preparation method thereof Pending CN113350212A (en)

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CN114028258A (en) * 2021-12-10 2022-02-11 朱学军 Whitening essence

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Application publication date: 20210907