CN113230541B - Sacral nerve stimulation device - Google Patents
Sacral nerve stimulation device Download PDFInfo
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- CN113230541B CN113230541B CN202110733118.5A CN202110733118A CN113230541B CN 113230541 B CN113230541 B CN 113230541B CN 202110733118 A CN202110733118 A CN 202110733118A CN 113230541 B CN113230541 B CN 113230541B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36062—Spinal stimulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36125—Details of circuitry or electric components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/36139—Control systems using physiological parameters with automatic adjustment
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- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
- H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
- H02J50/10—Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
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- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
- H02J7/00—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
- H02J7/0029—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries with safety or protection devices or circuits
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- H—ELECTRICITY
- H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
- H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
- H02J7/00—Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
- H02J7/007—Regulation of charging or discharging current or voltage
- H02J7/00712—Regulation of charging or discharging current or voltage the cycle being controlled or terminated in response to electric parameters
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Abstract
The invention discloses a sacral nerve stimulation device, which comprises a stimulation electrode, a pulse generator and an intelligent terminal, wherein the stimulation electrode is used for stimulating a load object, the pulse generator is in communication connection with the intelligent terminal, the intelligent terminal comprises a processor module, a communication module and a display module, the stimulation electrode is electrically connected with the pulse generator, the pulse generator is internally provided with the sacral nerve stimulation module, a spinal nerve stimulation module and a sphincter stimulation module, and the spinal nerve stimulation module comprises an electric stimulation module, a temperature and humidity detection module, a human body state detection module and a wireless transmission module; the stimulating electrode comprises a sacral nerve stimulating electrode, a spinal nerve stimulating electrode and a sphincter stimulating electrode. The invention can realize three stimulation modes simultaneously or separately, and the in-vitro telemetry equipment can transmit corresponding working modes, working states and electrode stimulation parameters to the in-vivo pulse generator through the wireless module, thereby meeting the change requirement of stimulation frequency and changing the frequency to improve the treatment effect.
Description
Technical Field
The invention belongs to the technical field of medical appliances, and relates to a sacral nerve stimulation device.
Background
The sacral nerve electric stimulator is also called as a bladder pacemaker, and is a novel minimally invasive and reversible therapy for treating bladder urination dysfunction. Sacral nerve stimulation, also known as sacral nerve modulation, is a medical electrical stimulation therapy. In terms of urination dysfunction, the symptoms of urinary frequency, urgent urinary incontinence, non-obstructive urinary retention of patients who are not or cannot tolerate conservative treatment (oral medication, behavioral treatment) are mainly treated. A programmable stimulator, the sacral nerve stimulator, is typically implanted subcutaneously, and is connected to the sacral nerve by a lead and delivers electrical stimulation. Since in these symptoms the nerves and brain are no longer able to communicate effectively, this results in dysfunction of the intestines/bladder. Treatment at this time often mimics signaling through the central nervous system. One major neural route is from the brain through the back along the spinal cord, which is commonly referred to as the sacral region. This area controls the daily functions of the pelvic floor, urinary sphincter, bladder and intestinal tract. By stimulating the sacral nerve (located in the posterior lumbar region), the stimulator can generate electrical signals that control pelvic floor contraction. Over time, these contractions will reconstruct the strength of the organs and muscles. This effectively relieves all symptoms of urination/defecation dysfunction and in many cases completely eliminates them.
The frequency of stimulation of the sacral nerve stimulation is required to vary during the course of treatment, on the one hand, when treating different conditions, and on the other hand, when treating the same condition, a single frequency of long-term stimulation also tends to cause the patient to develop tolerance, changing the frequency to improve the efficacy of the treatment.
Meanwhile, the sacral nerve stimulator is used for treating diseases including, but not limited to, urinary excretion dysfunction, constipation, stress incontinence, urge incontinence, urinary retention dysfunction, pelvic pain, prostatitis, prostatodynia and the like.
The existing devices therefore do not meet the above requirements.
Disclosure of Invention
In order to solve the above problems, the present invention provides a sacral nerve stimulation device, which can realize three stimulation modes simultaneously or separately, and an external telemetry device can transmit corresponding working modes, working states and electrode stimulation parameters to an internal pulse generator through a wireless module, so as to meet the requirement of change of stimulation frequency, and change the frequency to improve the treatment effect.
The technical scheme of the invention is as follows:
the sacral nerve stimulation device comprises a stimulation electrode, a pulse generator and an intelligent terminal, wherein the stimulation electrode is used for stimulating a load object, the pulse generator is in communication connection with the intelligent terminal, the intelligent terminal comprises a processor module, a communication module and a display module, the stimulation electrode is electrically connected with the pulse generator, the sacral nerve stimulation module, a spinal nerve stimulation module and a sphincter stimulation module are arranged in the pulse generator, and the spinal nerve stimulation module comprises an electric stimulation module, a temperature and humidity detection module, a human body state detection module and a wireless transmission module; the stimulation electrodes include a sacral nerve stimulation electrode connected to a sacral nerve stimulation module, a spinal nerve stimulation electrode connected to a spinal nerve stimulation module, and a sphincter stimulation electrode connected to a sphincter stimulation module.
The temperature and humidity detection module is used for detecting the tightness of the equipment and guaranteeing the reliability of the equipment; the human body state detection module is used for detecting the action states of a patient, such as running, sleeping, walking and the like, and outputting different stimulation frequencies to the patient according to different states.
Preferably, the sacral nerve stimulating electrodes are one, the spinal nerve stimulating electrodes are two, the sphincter stimulating electrodes are one, and the processor module comprises a first processor for controlling the sacral nerve stimulating electrodes, a second processor for controlling the spinal nerve stimulating electrodes and a third processor for controlling the sphincter stimulating electrodes.
Preferably, the electric stimulation module comprises a complete machine power supply module, an electric stimulation voltage control module and an electric stimulation output module, wherein the complete machine power supply module comprises a charging coil, the charging coil is electrically connected to a storage battery through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit and a battery charging management module in sequence, and the storage battery is electrically connected to a main control MCU through the DC/DC module and a step-up and step-down circuit; the step-up and step-down circuit is further connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is further electrically connected to the battery through a DC/DC module; the voltage reference module is connected to the data selector through the D/A digital-to-analog conversion module, the current source module and the reversing circuit in sequence; the current source module, the reversing circuit and the data selector are electrically connected to the boost circuit.
Preferably, the electric stimulation voltage control module and the electric stimulation output module comprise charging coils, the charging coils are electrically connected to a storage battery sequentially through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit and a battery charging management module, and the storage battery is electrically connected to a main control MCU through the DC/DC module and a step-up/down circuit; the step-up and step-down circuit is further connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is further electrically connected to the battery through a DC/DC module; the voltage reference module is electrically connected to the load object through the D/A digital-to-analog conversion module, the current source module, the reversing circuit, the data selector and the capacitor array in sequence; the D/A digital-to-analog conversion module, the reversing circuit and the data selector are all electrically connected to the main control MCU, and the current source module, the reversing circuit and the data selector are electrically connected to the booster circuit.
Preferably, the stimulation electrode tip is provided with a stimulation point in contact with the nerve, which is held in contact with the nerve by a fixation or clamping device.
Preferably, the stimulating electrode is made of one or more of silver, platinum alloy, nickel and nickel alloy, the outer sleeve of the stimulating electrode is a medical polymer insulating tube, and the medical polymer material adopted in the medical polymer insulating tube can be one or more of nylon, polyurethane and polytetrafluoroethylene.
Preferably, the intelligent terminal is a palm computer, a PDA or a smart phone, and the intelligent terminal further comprises keys, wherein the keys comprise a switch key, a navigation key, a display screen, a stimulation voltage increasing key, a stimulation voltage decreasing key, a stimulation starting key, a stimulation closing key and a synchronous key.
Preferably, the device further comprises a wireless charger for charging the pulse generator.
Preferably, the wireless communication module is connected with the intelligent terminal through a Zigbee, bluetooth or infrared communication mode.
The invention has the beneficial effects that: the invention has three electrode leads, can realize three stimulation modes simultaneously or separately, and the external telemetry equipment can transmit corresponding working modes, working states and electrode stimulation parameters to the internal pulse generator through the wireless module, thereby meeting the change requirement of stimulation frequency and changing the frequency to improve the treatment effect; the invention also provides an electric stimulation device, wherein the current output by the pain electric stimulation current source is fed to the reversing circuit, and meanwhile, the main control is used for controlling the reversing circuit to perform current reversing on the current fed to the reversing circuit, so that the output current is ensured to have positive and negative directions, and the output current can be accurately controlled.
Drawings
Fig. 1 is a schematic structural diagram of an apparatus according to an embodiment of the present invention.
Fig. 2 is a perspective view of an in vivo structural arrangement of an embodiment of the present invention.
Fig. 3 is a diagram of the overall architecture of the electro-stimulation module.
Fig. 4 is a diagram of the overall architecture of the overall power module.
Fig. 5 is a diagram showing the overall architecture of the electric stimulation voltage control module and the electric stimulation output module.
Fig. 6 is a schematic structural diagram of an intelligent terminal.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the drawings attached to the specification.
The sacral nerve stimulation device comprises a pulse generator 1 implanted in a human body, an intelligent terminal 2 arranged outside the human body for remote measurement and a stimulation electrode implanted in the human body, wherein the pulse generator 1 is in communication connection with the intelligent terminal 2, and the stimulation electrode is electrically connected with the pulse generator 1. The intelligent terminal 2 comprises a processor module, a communication module and a display module, wherein the pulse transmitter 1 is provided with a sacral nerve stimulation module, a spinal nerve stimulation module and a sphincter stimulation module, and the spinal nerve stimulation module comprises an electric stimulation module, a temperature and humidity detection module, a human body state detection module and a wireless transmission module; the stimulation electrodes include a sacral nerve stimulation electrode connected to a sacral nerve stimulation module, a spinal nerve stimulation electrode connected to a spinal nerve stimulation module, and a sphincter stimulation electrode connected to a sphincter stimulation module.
As an embodiment of the present invention, the stimulation electrodes implanted in the body have three or four electrode leads, one being the sacral nerve stimulation electrode 4, one or two being the medical pain stimulation electrode 5, one being the sphincter stimulation electrode 6, and one being an external telemetry device. The user can send related control instructions to the pulse generator 1 through the intelligent terminal 2, such as respectively sending sacral nerve stimulation signals to treat urinary incontinence and other symptoms, and sending pain treatment stimulation signals to treat pelvic pain and other related pain signals and stimulate sphincter signals.
As one embodiment of the invention, the processor module includes a first processor for controlling the sacral nerve stimulation electrode, a second processor for controlling the spinal nerve stimulation electrode, and a third processor for controlling the sphincter stimulation electrode.
The stimulation device can be divided into three stimulation systems, namely a sacral nerve stimulation system, a spinal nerve stimulation system and a sphincter stimulation system, wherein the sacral nerve stimulation module comprises an intelligent terminal 2, a sacral nerve stimulation module and a sacral nerve stimulation electrode, which are arranged in the pulse emitter 1, the spinal nerve stimulation system comprises the intelligent terminal 2, the spinal nerve stimulation module and the spinal nerve stimulation electrode, which are arranged in the pulse emitter 1, and the sphincter stimulation system comprises the intelligent terminal 2, the sphincter stimulation module and the sphincter stimulation electrode, which are arranged in the pulse emitter 1. The intelligent terminals in the three systems are the same device.
As an embodiment of the present invention, as shown in fig. 2, the sacral nerve stimulation system includes a sacral nerve stimulation electrode 4, which is electrically connected to an in vivo implanted pulse generator module through a feedthrough, a stimulation point contacting with the sacral nerve 3-2 is provided at the end of the sacral nerve stimulation electrode 4, the electrode end can be kept in good contact with the sacral nerve 3-2 by a fixing or clamping device, and the stimulation electrode must be designed to meet the conditions of long-term implantation, i.e., no toxicity, minimal foreign body reaction, good biocompatibility, etc.
As an embodiment of the present invention, as shown in FIG. 2, the spinal nerve stimulating system comprises a spinal nerve stimulating electrode 5, which is a stimulating electrode for treating pain, the spinal nerve stimulating electrode 5 is electrically connected with an in-vivo implanted pulse generator module through a feed-through, the tail end of the spinal nerve stimulating electrode 5 is provided with a stimulating point contacting with the spinal nerve 3-3, the tail end of the electrode can be kept in good contact with the spinal nerve 3-3 through a fixing or clamping device, and the stimulating electrode must be designed to meet the condition of being implanted for a long time, i.e., no toxicity, minimal foreign body reaction, good biocompatibility, etc.
As an embodiment of the present invention, as shown in fig. 2, the sphincter stimulation module includes a stimulation sphincter electrode 6, that is, the stimulation sphincter electrode 6, which is electrically connected to the in vivo implantation pulse generator module through a feedthrough, the stimulation sphincter electrode 6 is provided with a stimulation point such as S3, S4 at the end thereof, which is in good contact with the nerve root of the sphincter attachment, and the electrode end is made to maintain good contact with the sphincter nerve by a fixing or clamping device, so that the stimulation electrode must be designed to meet the conditions of long-term implantation, that is, non-toxicity, minimal foreign body reaction, good biocompatibility, etc.
As one implementation mode of the invention, the three stimulating electrodes are all made of one or more of silver, platinum alloy, nickel and nickel alloy, the outer sleeve of the stimulating electrode is a medical polymer insulating tube, and the medical polymer material adopted in the medical polymer insulating tube can be one or more of nylon, polyurethane and polytetrafluoroethylene.
As an embodiment of the invention, as shown in fig. 3, the electric stimulation module comprises a complete machine power supply module, an electric stimulation voltage control module and an electric stimulation output module, wherein the electric stimulation module comprises a charging coil, the charging coil is electrically connected to a storage battery through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit and a battery charging management module in sequence, and the storage battery is electrically connected to a main control MCU through a DC/DC module and a buck-boost circuit; the step-up and step-down circuit is also connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is also electrically connected to the battery through a DC/DC module; the voltage reference module is electrically connected to the load object through the D/A digital-to-analog conversion module, the current source module, the reversing circuit, the data selector and the capacitor array in sequence; the D/A digital-to-analog conversion module, the reversing circuit and the data selector are all electrically connected to the main control MCU, and the current source module, the reversing circuit and the data selector are electrically connected to the booster circuit; the main control MCU is also electrically connected to the charging coil through the reverse modulation module.
The reverse modulation module is used for transmitting data by adjusting the change of the resonance frequency of the charging coil through the change of the voltage control resonance capacitor, when the resonance frequency of the charging coil is changed, the reverse impedance on the transmitting coil of the wireless charger is changed, the output voltage waveform of the radio frequency power amplifier of the external machine is changed, the change reflects the change of the resonance frequency of the implant, and the voltage waveform of the implant control resonance capacitor change, namely the detailed information of the data to be transmitted, can be obtained by demodulating the envelope of the voltage waveform.
As an embodiment of the present invention, as shown in fig. 4, the power supply module of the whole machine includes a charging coil, the charging coil is electrically connected to a storage battery sequentially through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit, and a battery charging management module, and the storage battery is electrically connected to a main control MCU through the DC/DC module and a step-up/down circuit; the step-up and step-down circuit is also connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is also electrically connected to the battery through a DC/DC module; the voltage reference module is connected to the data selector through the D/A digital-to-analog conversion module, the current source module and the reversing circuit in sequence; the current source module, the reversing circuit and the data selector are electrically connected to the boost circuit.
As an embodiment of the present invention, as shown in fig. 5, the electric stimulation voltage control module and the electric stimulation output module include a charging coil, the charging coil is electrically connected to a storage battery sequentially through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit, and a battery charging management module, and the storage battery is electrically connected to a main control MCU through the DC/DC module and a step-up/down circuit; the step-up and step-down circuit is also connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is also electrically connected to the battery through a DC/DC module; the voltage reference module is electrically connected to the load object through the D/A digital-to-analog conversion module, the current source module, the reversing circuit, the data selector and the capacitor array in sequence; the D/A digital-to-analog conversion module, the reversing circuit and the data selector are all electrically connected to the main control MCU, and the current source module, the reversing circuit and the data selector are electrically connected to the booster circuit.
As an embodiment of the present invention, a wireless charger for charging the pulse generator is further included. The power information can be transmitted to a display module of the intelligent device outside the body through a wireless communication technology. When the electric quantity of the in-vivo pulse generator is too low, the in-vivo pulse generator is charged by the in-vitro wireless charger.
The operation process of the electric stimulation module is as follows:
Firstly, the wireless charger is used for wirelessly charging the internal coil, current received by the internal charging coil passes through the AD/DC module, so that direct current is formed, the formed direct current is subjected to overvoltage and overcurrent protection, voltage and current in a circuit are monitored and detected, then the current is conducted to the electromagnetic battery charging management module, and the battery charging management module is used for providing the current for the lithium ion battery.
When the integral device starts to work, the lithium ion battery output power supply passes through the DC/DC switch power supply, so that the functions of short-circuit protection, overvoltage protection, undervoltage protection, overcurrent protection, other protection and the like of the lithium ion battery output power supply are realized, and finally, corresponding voltages are output through the DC/DC power supply and the Buck-Boost voltage-boosting module and provided for the main control MCU and the voltage reference module, so that the power supply of the main control MCU and the high-precision reference voltage are realized.
The current source module outputs corresponding electric stimulation current waveforms according to the voltage waveforms output by the D/A digital-to-analog converter. The current is directly output to a subsequent commutation circuit and output to a load through a MUX.
Meanwhile, the voltage reference module feeds back the required accurate voltage value to the main control MCU, and the main control MCU sends out a control signal which passes through the DP digital point potentiometer module and then controls and adjusts the voltage value output by the Boost circuit module by using the DP digital potentiometer module. And then, the current source module, the reversing circuit and the MUX are respectively powered by corresponding voltage after Boost.
As described above, the corresponding voltage output by the DC/DC is transmitted to the voltage reference module through the Buck-Boost voltage-boosting module, meanwhile, the voltage reference module feeds back the required accurate voltage value to the main control MCU, meanwhile, the main control MCU sends out a control signal, the control signal passes through the DP digital potentiometer module, the DP digital potentiometer module DP is only a variable resistor, the main control MCU firstly controls the DP digital potentiometer module, different resistance values are output to the feedback end of the Boost voltage-boosting circuit, and then the Boost outputs different direct current voltage values.
And controlling and adjusting the voltage value output by the Boost circuit module. And then, the current source module, the reversing circuit and the MUX are respectively powered by corresponding voltage after Boost.
And then the main control MCU respectively controls the digital-analog D/A conversion modules, continuous signal output is obtained through D/A conversion, the maximum voltage output by the D/A conversion is determined by the reference voltage, and meanwhile, the main control MCU is used for controlling the D/A conversion modules, and finally, the signals sent by the D/A conversion modules are output to the current sources, so that the function of controlling and outputting currents with different sizes and shapes is realized.
The main control MCU controls the reversing circuit to perform current reversing to the current input to the reversing circuit, so that the current source module which is used for outputting unidirectional current in the positive direction and the reverse direction can only output unidirectional current, and the reversing circuit can be used for outputting bidirectional current.
And output to MUX, and output to nerve fiber via capacitor array to achieve the purpose of electrically stimulating nerve. The main control MCU controls the MUX multiplexer to control the transmission output position of current, the current is output to the capacitor array through the MUX multiplexer and then is output to a load (namely nerve fibers, muscle tissues and the like), and the purpose of using the capacitor array is to avoid polarization easily caused by direct current transmission to the load due to direct current transmission to the electrode.
As an embodiment of the present invention, as shown in fig. 6, the smart terminal is a palm computer, a PDA or a smart phone, and the smart terminal further includes keys including a switch key 21, a navigation key 22, a display screen 23, a stimulus voltage increasing key 24, a stimulus voltage decreasing key 25, a stimulus on key 26, a stimulus off key 27, and a synchronization key 28.
The intelligent terminal 2 can respectively telemeter (program) the sacral nerve stimulation system and the spinal nerve stimulation system through the communication module, so as to transmit corresponding control instructions to the sacral nerve stimulation system and the spinal nerve stimulation system, can manually start or close the sacral nerve stimulation system and the spinal nerve stimulation system through external telemetering equipment, and can also display related parameters such as working modes, working states, electrode stimulation parameters and the like of the sacral nerve stimulation system and the spinal nerve stimulation system on the display module.
As an embodiment of the invention, the stimulation electrode is connected to the pulse generator via a feedthrough.
Finally, it should be noted that: the above examples are only specific embodiments of the present invention, and are not intended to limit the scope of the present invention, but it should be understood by those skilled in the art that the present invention is not limited thereto, and that the present invention is described in detail with reference to the foregoing examples: any person skilled in the art may modify or easily conceive of the technical solution described in the foregoing embodiments, or perform equivalent substitution of some of the technical features, while remaining within the technical scope of the present disclosure; such modifications, changes or substitutions do not depart from the spirit and scope of the corresponding technical solutions. Are intended to be encompassed within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (6)
1. The sacral nerve stimulation device is characterized by comprising a stimulation electrode, a pulse generator and an intelligent terminal, wherein the stimulation electrode is used for stimulating a load object, the pulse generator is in communication connection with the intelligent terminal, the intelligent terminal comprises a processor module, a communication module and a display module, the stimulation electrode is electrically connected with the pulse generator, the sacral nerve stimulation module, the spinal nerve stimulation module and the sphincter stimulation module are arranged in the pulse generator, and the spinal nerve stimulation module comprises an electric stimulation module, a temperature and humidity detection module, a human body state detection module and a wireless transmission module; the stimulation electrodes include a sacral nerve stimulation electrode connected to a sacral nerve stimulation module, a spinal nerve stimulation electrode connected to a spinal nerve stimulation module, a sphincter stimulation electrode connected to a sphincter stimulation module; the sacral nerve stimulating electrode is provided with one, the spinal nerve stimulating electrodes are provided with two, the sphincter stimulating electrode is provided with one, and the processor module comprises a first processor for controlling the sacral nerve stimulating electrode, a second processor for controlling the spinal nerve stimulating electrode and a third processor for controlling the sphincter stimulating electrode; the electric stimulation module comprises a complete machine power supply module, an electric stimulation voltage control module and an electric stimulation output module, the complete machine power supply module comprises a charging coil, the charging coil is electrically connected to a storage battery through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit and a battery charging management module in sequence, and the storage battery is electrically connected to a main control MCU through the DC/DC module and a voltage-boosting circuit; the step-up and step-down circuit is further connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is further electrically connected to the battery through a DC/DC module; the voltage reference module is connected to the data selector through the D/A digital-to-analog conversion module, the current source module and the reversing circuit in sequence; the current source module, the reversing circuit and the data selector are electrically connected to the boost circuit;
The electric stimulation voltage control module and the electric stimulation output module comprise charging coils, the charging coils are electrically connected to a storage battery through an AD/DC module, an overvoltage protection circuit, an overcurrent protection circuit and a battery charging management module in sequence, and the storage battery is electrically connected to a main control MCU through the DC/DC module and a step-up and step-down circuit; the step-up and step-down circuit is further connected to the main control MCU through a circuit and a voltage reference module, the main control MCU is electrically connected to the step-up circuit through a DP digital potentiometer, and the step-up circuit is further electrically connected to the battery through a DC/DC module; the voltage reference module is electrically connected to the load object through the D/A digital-to-analog conversion module, the current source module, the reversing circuit, the data selector and the capacitor array in sequence; the D/A digital-to-analog conversion module, the reversing circuit and the data selector are all electrically connected to the main control MCU, and the current source module, the reversing circuit and the data selector are electrically connected to the booster circuit;
when the integral device starts to work, the output power of the storage battery passes through the DC/DC module, so that the functions of short-circuit protection, overvoltage protection, undervoltage protection, overcurrent protection and other protection of the output power of the storage battery are realized, and finally, the power passing through the DC/DC is provided for the main control MCU and the voltage reference module by outputting corresponding voltage through the Buck-Boost step-down circuit, so that the power supply and high-precision reference voltage of the main control MCU are realized;
The voltage reference module feeds back the required accurate voltage value to the main control MCU, the main control MCU sends out a control signal, the control signal passes through the DP digital potentiometer, the DP digital potentiometer is used for controlling and adjusting the voltage value output by the boosting circuit, and then the current source module, the reversing circuit and the data selector are respectively powered by corresponding voltage after Boost;
The main control MCU is used for respectively controlling the D/A digital-to-analog conversion modules, continuous signal output is obtained through D/A digital-to-analog conversion, the maximum voltage output by the D/A digital-to-analog conversion is determined by the reference voltage, meanwhile, the main control MCU is used for controlling the D/A digital-to-analog conversion modules, and finally, signals sent by the D/A are output to the current source modules, so that the function of controlling and outputting currents with different sizes and shapes is realized.
2. The sacral nerve stimulation device according to claim 1, wherein the stimulation electrodes are connected to the pulse generator by a feedthrough.
3. The sacral nerve stimulation device according to claim 1, wherein the stimulation electrode tip is provided with stimulation points that contact the nerve, the stimulation points being held in contact with the nerve by a fixation or clamping device.
4. The sacral nerve stimulation device according to claim 1, wherein the stimulation electrode is made of one or more of silver, platinum alloy, nickel and nickel alloy, the outer sleeve of the stimulation electrode is a medical polymer insulating tube, and the medical polymer material adopted in the medical polymer insulating tube is one or more of nylon, polyurethane and polytetrafluoroethylene.
5. The sacral nerve stimulation device of claim 1, wherein the smart terminal is a palm top computer or a smart phone, the smart terminal further comprising keys including a switch key, a navigation key, a stimulation voltage increase key, a stimulation voltage decrease key, a stimulation on key, a stimulation off key, a synchronization key.
6. The sacral nerve stimulation device according to claim 1, further comprising a wireless charger for charging the pulse generator.
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| CN2020112715551 | 2020-11-13 | ||
| CN202011271555.1A CN112402793A (en) | 2020-11-13 | 2020-11-13 | Sacral nerve stimulation device |
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| CN115245414A (en) * | 2021-04-28 | 2022-10-28 | 合肥工业大学 | A kind of intelligent ankle-foot orthosis and production method |
| CN113907761B (en) * | 2021-10-09 | 2024-05-07 | 中国人民解放军军事科学院军事医学研究院 | Bipolar implantable myoelectric electrode assembly for stimulation and recording and application method thereof |
| CN114042252A (en) * | 2021-11-09 | 2022-02-15 | 北京惠仁阳光医疗器械有限公司 | Portable nerve dry magnetic stimulation rehabilitation treatment equipment |
| CN115738078B (en) * | 2022-11-09 | 2023-11-10 | 杭州神络医疗科技有限公司 | Low-power-consumption operation method and device based on battery voltage |
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