CN1130219C

CN1130219C - Litholysizing bear gall powder

Info

Publication number: CN1130219C
Application number: CN01128739A
Authority: CN
Inventors: 王继平
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-07-26
Filing date: 2001-07-26
Publication date: 2003-12-10
Anticipated expiration: 2021-07-26
Also published as: CN1334119A

Abstract

The present invention relates to a traditional Chinese medicine for treating calculi of the liver and the gallbladder, which is prepared from 6 to 180 of longhairy antenoron herb, 6 to 15 of artemisia capillaries, 10 to 20 of galli stomachichum corium, 10 to 30 of white paeony root, 3 to 10 of matrimony vine, 10 to 25 of giant knotweed, 6 to 10 of costustoot, 6 to 10 of bitter orange, 6 to 30 of green tangerine peel, 10 to 25 of tangerine peel, 6 to 10 of nutgrass galingale rhizome, 10 to 30 of curcuma, 10 to 15 of mirabilite, 10 to 20 of rhubarb, 10 to 30 of herba pyrrosiae, 5 to 10 of liquorice, 10 to 30 of raw milkvetch root, 6 to 10 of bupleurum root, 6 to 10 of scutellaria, 6 to 15 of pumice pumex, 10 to 15 of raw haw, 6 to 15 of massa medicata fermentata, 6 to 15 of wheat germ, 10 to 60 of Chinese clematis, 3 to 8 of coptis, 10 to 40 of nacre, 10 to 20 of rehmannia root, 5 to 15 of bear gall and 6 to 10 of alum. The traditional Chinese medicine has the efficiency for dispersing stagnated liver qi, relieving qi stagnation, reducing fever, promoting the functions of the gallbladder, nourishing the liver, the gallbladder and yin blood, resolving phlegm and stasis and removing hepatic calculi. The present invention has the advantages of reasonable prescription and proper preparation, and thus, the traditional Chinese medicine has favorable therapeutical effects on cholelithiasis.

Description

The powder of treatment liver and bile stone

Technical field

The present invention relates to-kind with the pharmaceutical product of animals and plants, especially for the Litholysizing bear gall powder of treatment liver and bile stone as raw material.

Background technology

Existing is the dissolved stone medicine of main component with the Chinese herbal medicine, as CN1158740, in its prescription with Radix Gentianae as main component because this medical herbs distributes seldom, make cost higher.

Summary of the invention

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Herba Lysimachiae 6-180, Herba Artemisiae Scopariae 6-15, Endothelium Corneum Gigeriae Galli 10-20, Radix Paeoniae Alba 10-30, Fructus Lycii 3-10, Rhizoma Polygoni Cuspidati 10-25, Radix Aucklandiae 6-10, Fructus Aurantii 6-10, Pericarpium Citri Reticulatae Viride 6-30, Pericarpium Citri Reticulatae 10-25, Rhizoma Cyperi 6-10, Radix Curcumae 10-30 Natrii Sulfas 10-15, Radix Et Rhizoma Rhei 10-20, Folium Pyrrosiae 10-30, Radix Glycyrrhizae 5-10, Radix Astragali 10-30, Radix Bupleuri 6-10, Radix Scutellariae 6-10, Pumex 6-15 Fructus Crataegi 10-15, Massa Medicata Fermentata 6-15, Fructus Hordei Germinatus 6-15, Radix Clematidis 10-60, Rhizoma Coptidis 3-8, Concha Margaritifera 10-40, Radix Rehmanniae 10-20, Fel Ursi 5-15, Alumen 6-10.

With above component levigation, 100 orders that sieve, encapsulated or make powder, honeyed pill, the watered pill and all can behind mixing, the disinfection by ultraviolet light.

The present invention has the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, clearing heat secreting bile, the cloudy blood of nourishing the liver gallbladder, the stasis of blood of reducing phlegm, the molten hepatolith that disappears, and is used for liver and bile stone, acute and chronic cholecystitis, again fatty liver, gallbladder hydrops, urinary system calculus is had significant curative effect simultaneously.Have no wound, no pain, take medicine conveniently, have no side effect, calculus dissolving and excreting rate height, treat cholelithiasis 67 examples altogether, male's 24 examples, women's 43 examples, age 25-50 year 39 examples, person's 28 examples more than 50 years old, non-evident sympton or only show general indigestion symptom person 43 examples usually, stomachache arranged, feel sick, symptom's 24 examples such as vomiting, all patients are all through the Abdominal B type ultrasonography inspection more than twice or remake X line, CT, cholangiography inspection and make a definite diagnosis.Cure (the calculus image disappears, and symptom and sign disappear) 36 examples (53.73%), effectively (the calculus image dwindles, symptom and sign obviously alleviate) 22 examples (32.84%), invalid (calculus image no change, sx, sign or deposit) 9 examples (13.43%), total effective rate is 83.57%.

Below be the 67 routine clinical research reports of Litholysizing bear gall powder treatment cholelithiasis:

Cholelithiasis is surgical common disease, frequently-occurring disease, it is generally acknowledged and mostly be cholestasis, biliary tract antibacterial and parasitic infection, the cholesterol metabolism imbalance is principal element, the applicant since nineteen ninety-eight, to intend Litholysizing bear gall powder prescription therapeutic cholelithiasis 67 examples certainly, satisfactory effect now is summarized as follows in clinical practice:

1, clinical data

1.1 the patient of 67 routine patients for the special outpatient clinic treatment organized in treatment, male's 24 examples, women's 43 examples, age 25-50 year 39 examples, person's 28 examples more than 50 years old, non-evident sympton or only show general dyspepsia person's 43 examples usually, stomachache arranged, feel sick, symptom's 24 examples such as vomiting, all patients are all through the Abdominal B type ultrasonography inspection more than 2 times or remake X line, CT, gallbladder examination and make a definite diagnosis.

1.2 matched group 42 routine patients compare there was no significant difference from two groups of sexes of patient, age, the course of disease, the state of an illness, cardinal symptom, the professional aspect of treatment through making a definite diagnosis, and have comparability.

2, Therapeutic Method

2.1 the treatment group is made up of 29 pleasant impression Chinese medicines such as Fel Ursi, Natrii Sulfas, Alumen, Herba Artemisiae Scopariae, Radix Astragali, Radix Curcumae, Radix Et Rhizoma Rhei, names to be Litholysizing bear gall powder, drug dose is grasped flexibly according to patient age, body constitution, every day 3 times, and taking medicine after meal, 30 days is 1 course of treatment.

2.2 matched group is obeyed cholagogic and lithagogue tablet 3 times every day, each 5.

3, therapeutic outcome

3.1 criterion of therapeutical effect: adopt the whole nation unified diagnosis and curative effect judging standard, cure: sings and symptoms disappears, and imaging examination (B ultrasonic, PTC, ERCP, biliary tract vein or oral appearance must have wherein 2 kinds of inspection methods) calculus disappears; Produce effects: sings and symptoms alleviates, imaging examination, and calculus has obvious minimizing, reach more than 1/2, or calculus diminishes 1/2 above person; Effectively: sings and symptoms has and alleviates, and the imaging examination calculus reduces or the person of diminishing before the treatment; Invalid: the sings and symptoms no change, the imaging examination calculus does not have the changer.

3.2 two groups of total effectses relatively treatment are organized 67 examples, curing 36 examples (53.73%), produce effects 22 examples (32.84%), invalid 9 examples (13.43%), total effective rate is 86.57% matched group, 42 examples, cure 3 examples (7.14%), produce effects 16 examples (38.10%), invalid 13 examples (53.76%), 45.24%, two group of cure rate difference of total effective rate significance (ρ＜0.05) is arranged.

4, brief summary

Clinical observation result shows, Litholysizing bear gall powder treatment cholelithiasis total effective rate is 86.57%, and cure rate is 53.73%, acts on really, evident in efficacy, obviously is better than the control drug cholagogic and lithagogue tablet.

Litholysizing bear gall powder serves as main the composition with Chinese herbal medicine, mineral medicine and animal drugs, has the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, clearing heat secreting bile, nourishing the liver gallbladder cloudy blood, the stasis of blood of reducing phlegm, the molten hepatolith that disappears, full side's reasonable recipe, and compatibility is proper, thereby cholelithiasis is had the good curing effect.

Litholysizing bear gall powder is dosage form for oral administration, taking convenience, and no wound, no pain, clinical trial has no side effect, calculus dissolving and excreting rate height.

The specific embodiment 1:

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Herba Lysimachiae 6, Herba Artemisiae Scopariae 15, Endothelium Corneum Gigeriae Galli 10, the Radix Paeoniae Alba 30, Fructus Lycii 10, Rhizoma Polygoni Cuspidati 10, the Radix Aucklandiae 10, Fructus Aurantii 6, Pericarpium Citri Reticulatae Viride 18, Pericarpium Citri Reticulatae 18, Rhizoma Cyperi 8, Radix Curcumae 20, Natrii Sulfas 15, Radix Et Rhizoma Rhei 10, Folium Pyrrosiae 30, Radix Glycyrrhizae 5, Radix Astragali 10, Radix Bupleuri 10, Radix Scutellariae 6, Pumex 15 Fructus Crataegi 13, Massa Medicata Fermentata 10, Fructus Hordei Germinatus 10, Radix Clematidis 30, Rhizoma Coptidis 5, Concha Margaritifera 25, the Radix Rehmanniae 15, Fel Ursi 8, Alumen 8.With above component levigation, 100 orders that sieve, encapsulatedly behind mixing, the disinfection by ultraviolet light all can.

The specific embodiment 2:

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Herba Lysimachiae 180, Herba Artemisiae Scopariae 6, Endothelium Corneum Gigeriae Galli 10, the Radix Paeoniae Alba 30, Fructus Lycii 3, Rhizoma Polygoni Cuspidati 10, the Radix Aucklandiae 6, Fructus Aurantii 10, Pericarpium Citri Reticulatae Viride 30, Pericarpium Citri Reticulatae 10, Rhizoma Cyperi 10, Radix Curcumae 10 Natrii Sulfas 10, Radix Et Rhizoma Rhei 20, Folium Pyrrosiae 10, Radix Glycyrrhizae 5, Radix Astragali 10, Radix Bupleuri 6, Radix Scutellariae 10, Pumex 6 Fructus Crataegi 15, Massa Medicata Fermentata 6, Fructus Hordei Germinatus 15, Radix Clematidis 10, Rhizoma Coptidis 8, Concha Margaritifera 10, the Radix Rehmanniae 20, Fel Ursi 5, Alumen 10.With above component levigation, 100 orders that sieve, make powder behind mixing, the disinfection by ultraviolet light.

The specific embodiment 3:

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Herba Lysimachiae 80, Herba Artemisiae Scopariae 9, Endothelium Corneum Gigeriae Galli 15, the Radix Paeoniae Alba 20, Fructus Lycii 6, Rhizoma Polygoni Cuspidati 18, the Radix Aucklandiae 6, Fructus Aurantii 8, Pericarpium Citri Reticulatae Viride 6, Pericarpium Citri Reticulatae 25, Rhizoma Cyperi 6, Radix Curcumae 30g Natrii Sulfas 13, Radix Et Rhizoma Rhei 15, Folium Pyrrosiae 20, Radix Glycyrrhizae 7, Radix Astragali 30, Radix Bupleuri 10, Radix Scutellariae 6, Pumex 15, Fructus Crataegi 10, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 6, Radix Clematidis 60, Rhizoma Coptidis 3, Concha Margaritifera 40, the Radix Rehmanniae 10, Fel Ursi 15, Alumen 6.With above component levigation, 100 orders that sieve, make the watered pill behind mixing, the disinfection by ultraviolet light.

Claims

1. powder for the treatment of liver and bile stone is characterized in that it is made up of the component of following weight portion: Herba Lysimachiae 6-180, Herba Artemisiae Scopariae 6-15, Endothelium Corneum Gigeriae Galli 10-20, Radix Paeoniae Alba 10-30, Fructus Lycii 3-10, Rhizoma Polygoni Cuspidati 10-25, Radix Aucklandiae 6-10, Fructus Aurantii 6-10, Pericarpium Citri Reticulatae Viride 6-30, Pericarpium Citri Reticulatae 10-25, Rhizoma Cyperi 6-10, Radix Curcumae 10-30 Natrii Sulfas 10-15, Radix Et Rhizoma Rhei 10-20, Folium Pyrrosiae 10-30, Radix Glycyrrhizae 5-10, Radix Astragali 10-30, Radix Bupleuri 6-10, Radix Scutellariae 6-10, Pumex 6-15, Fructus Crataegi 10-15, Massa Medicata Fermentata 6-15, Fructus Hordei Germinatus 6-15, Radix Clematidis 10-60, Rhizoma Coptidis 3-8, Concha Margaritifera 10-40, Radix Rehmanniae 10-20, Fel Ursi 5-15, Alumen 6-10.