CN1616041A - Chinese medicine composition for treating chronic ulcerative colitis - Google Patents
Chinese medicine composition for treating chronic ulcerative colitis Download PDFInfo
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- CN1616041A CN1616041A CN 200410078380 CN200410078380A CN1616041A CN 1616041 A CN1616041 A CN 1616041A CN 200410078380 CN200410078380 CN 200410078380 CN 200410078380 A CN200410078380 A CN 200410078380A CN 1616041 A CN1616041 A CN 1616041A
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating chronic ulcerative colitis, and belongs to the field of Chinese medicine technology. The Chinese medicine composition is prepared with eight kinds of Chinese medicinal materials, including astragalus root, white atractylodes rhizome, haw, Dangshen, red peony root, etc. The medicine of the present invention is prepared in various preparation forms for easy taking. The medicine has the excellent effect of promoting granulation, promoting blood regeneration and promoting ulcer to heal and has high effective rate.
Description
[technical field]
The present invention relates to a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis, belong to the field of Chinese medicines.
[background technology]
Chronic ulcerative colitis is a kind of clinically common digestive system disease, and present western medicine produces effects very few, and side effect is many, easily recurrence.The therapeutic modality of Chinese medicine is a lot of at present, for example: application number: 98100231, denomination of invention " a kind of medicine for the treatment of chronic ulcerative colitis and preparation method thereof ", it is mainly formed by medical material infusions such as Radix Notoginseng, Margarita, Endoconcha Sepiae, Fructus Evodiaes.Effectively improve local microcirculation, dredge the meridian passage, putrefaction-removing granulation-promoting, protection ulcer surface are to reach therapeutic purposes; And for example: application number: 03101319, denomination of invention " a kind of colitis enema ", it be Herba Agrimoniae, the Radix Pulsatillae, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis, licorice, Pericarpium Papaveris, the Pseudobulbus Bletillae (Rhizoma Bletillae), etc. composition.Effect with sterilization detoxifcation, removing the necrotic tissue and promoting granulation, hemostasis antidiarrhea and analgesic.However, treatment does not still have specific medicament for chronic ulcerative colitis, and the curative effect of medicine of the prior art still can not be satisfactory.
[summary of the invention]
Therefore, still there is the vast market demand in people for the treatment chronic ulcerative colitis pharmaceutical preparation of better efficacy, and particularly curative effect is reliable, and it is fast that clinical symptoms is recovered, cure rate height, the Chinese medicine preparation that toxicity, side effect is relatively little.Up to the present, still find no the data of any destruction novelty of the present invention, present inventor people is through studying intensively for many years, by clinical practice and checking repeatedly, a large amount of clinical observation materials have been collected, obtained to the treatment chronic ulcerative colitis have the Chinese medicine composition of better curative effect, thereby finished the present invention.
Purpose of the present invention is exactly that a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis with better curative effect will be provided.
The present invention is achieved in that it mainly is to be made by following bulk drugs: the Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Fructus Crataegi, Radix Codonopsis, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Poria, Rhizoma Coptidis.
Drug component consumption of the present invention is that the following weight parts scope all has better curative effect:
30～70 parts of the Radixs Astragali, 10～40 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10～40 parts of Fructus Crataegis, 10～40 parts of Radix Codonopsis, 5～20 parts of Radix Paeoniae Rubra, 5～20 parts of the Radix Paeoniae Albas, 5～20 parts of Poria, 5～20 parts of Rhizoma Coptidis.
Be preferably: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Preparation technology uses " specification requirement of new Chinese medicine Study on Preparation " in principle, the effective constituent that mainly contains that uses modern preparation new technique to extract medicine is used as medicine, add some accessory substances,, can be made into capsule, electuary, tablet, oral liquid as water, sugar, starch etc.
Chinese medicine composition is decocted in water for oral dose, and every part is adopted gram to be unit, and every day, potion divided secondary to take, and two weeks were a course of treatment.
Medicine of the present invention is made other dosage forms, conveniently takes, and medication the longest 4 courses of treatment, the shortest 2 courses of treatment, to inside ulcer, do not hold back mouthful person for a long time and play the effect that the granulation promoting hemopoietic is put on flesh equally, the function of impelling ulcer healing is promptly arranged, total effective rate 92%.
[specific embodiment]
The present invention is described further by clinical observation test and embodiment.
Test example 1, clinical observation on the therapeutic effect data
Chronic ulcerative colitis is a kind of clinically common digestive system disease, and present western medicine produces effects very few, and side effect is many, and recurrence is many, and we adopt from intending Chinese medicine decoction and treat 68 examples, and satisfactory efficacy is now reported the result as follows:
1, physical data: this is organized 68 routine patients and all makes a definite diagnosis through enteroscopy, and all cases meet national digestive disease diagnostic criteria in 78 years, wherein male 38 examples, woman's 30 examples, minimum 22 years old of age, maximum 67 years old, the course of disease is the longest 11 years, and is the shortest 1.5 years, all accepts Western medicine or other treatment is invalid.Mainly show with dense hemafecia, Mucous Stool or hemafecia.Often with characteristics such as tenesmus, part is with inappetence, weak, nauseating, anemia, 1～4/HP of stool laboratory leukocyte, 3～5/HP of erythrocyte, mucous hyperemia under the intestinal mirror, edema, coarse rough, the pus tongue is all adhered on the intestinal mucosa surface, mucosal erosion, touch easily hemorrhage, stool is cultivated all negative.
2, Therapeutic Method: adopt from intending multiple intestinal soup decoction.Every day, potion divided secondary to take, and two weeks were a course of treatment, and prescription is as follows:
Radix Astragali 50g, Rhizoma Atractylodis Macrocephalae (parched), Fructus Crataegi, each 30g of Radix Codonopsis, Radix Paeoniae Rubra, each 15g of the Radix Paeoniae Alba, Poria, each 10g of Rhizoma Coptidis.
3, therapeutic outcome:
68 examples are cured 43 examples (symptom complete obiteration, stool routine examination are normal, enteroscopy intestinal mucosa recover normal); Produce effects 19 examples (symptom disappears substantially, stool routine examination is normal, and the intestinal mirror partly recovers); Invalid 5 examples (symptom no change); Improvement example 1 example, total effective rate 92%, medication the longest 4 courses of treatment, the shortest 2 courses of treatment.
4, know from experience: the traditional Chinese medical science claims " intestinal is out-of-the-way " to primary disease, and the common coldheat complex of primary disease, deficiency and excess see that also qi depression to blood stasis adopts the treatment by Chinese herbs cold and heat, reinforcement and elimination in combination with existing.Can wet three warmers, strong taste, hemopoietic granulation promoting, evacuation of pus expelling the toxic substance from the body with tonic of the Radix Astragali among the we, the Radix Astragali not only can be controlled human body skin table skin infection, and to inside ulcer, do not hold back mouthful person for a long time and play the effect that the granulation promoting hemopoietic is put on flesh equally, the function of impelling ulcer healing is promptly arranged.So we are worth clinical further research and application.
Embodiment 1: the preparation of electuary type of the present invention
Getting each composition bulk drugs is: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Preparation technology meets " specification requirement of new Chinese medicine Study on Preparation " in principle, use modern preparation new technique, said medicine dried be crushed to more than 100 orders, add some accessory substances, through decocting, concentrate, technology infusion such as mixing forms, every bag 10 grams of preparation electuary, per three comprise the suitable Radix Astragali 50 grams, Rhizoma Atractylodis Macrocephalae (parched) 30 grams, Fructus Crataegi 30 grams, Radix Codonopsis 30 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 15 grams, the active ingredient of Poria 10 grams, Rhizoma Coptidis 10 grams.
Embodiment 2: the preparation of oral agents dosage form of the present invention.
Getting each composition bulk drugs is: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
Preparation technology meets " specification requirement of new Chinese medicine Study on Preparation " in principle, said medicine is used modern preparation new technique, add some accessory substances, extract active ingredient and prepare oral agents, by the suitable Radix Astragali 50 grams of per three bottles of effective doses, Rhizoma Atractylodis Macrocephalae (parched) 30 grams, Fructus Crataegi 30 grams, Radix Codonopsis 30 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 15 grams, the active ingredient of Poria 10 grams, Rhizoma Coptidis 10 grams is calculated.
Claims (2)
1, a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis, it is characterized in that it mainly is to be made by following bulk drugs: 30～70 parts of the Radixs Astragali, 10～40 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 10～40 parts of Fructus Crataegis, 10～40 parts of Radix Codonopsis, 5～20 parts of Radix Paeoniae Rubra, 5～20 parts of the Radix Paeoniae Albas, 5～20 parts of Poria, 5～20 parts of Rhizoma Coptidis.
2, a kind of Chinese medicine composition for the treatment of chronic ulcerative colitis according to claim 1, it is characterized in that wherein the consumption of crude drug is: 50 parts of the Radixs Astragali, 30 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 30 parts of Fructus Crataegis, 30 parts of Radix Codonopsis, 15 parts of Radix Paeoniae Rubra, 15 parts of the Radix Paeoniae Albas, 10 parts of Poria, 10 parts of Rhizoma Coptidis.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410078380 CN1616041A (en) | 2004-09-27 | 2004-09-27 | Chinese medicine composition for treating chronic ulcerative colitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200410078380 CN1616041A (en) | 2004-09-27 | 2004-09-27 | Chinese medicine composition for treating chronic ulcerative colitis |
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| CN1616041A true CN1616041A (en) | 2005-05-18 |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857453B (en) * | 2006-03-03 | 2010-05-12 | 延边大学 | A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method |
| CN102370687A (en) * | 2011-11-17 | 2012-03-14 | 中国中医科学院中医临床基础医学研究所 | Compound Chinese medicinal preparation for treating colonitis and preparation method thereof |
| CN102008565B (en) * | 2009-09-07 | 2012-05-23 | 成都中医药大学 | A kind of pharmaceutical composition for treating ulcerative colitis and preparation method thereof |
| CN103893457A (en) * | 2014-03-31 | 2014-07-02 | 王红 | Traditional Chinese medicine for treating ulcerative colitis |
| CN104436088A (en) * | 2013-09-18 | 2015-03-25 | 香港浸会大学 | A kind of Chinese herbal medicine formula for treating inflammatory bowel disease and preparation method thereof |
| CN105998264A (en) * | 2016-06-19 | 2016-10-12 | 练燕华 | Traditional Chinese medicine for treating chronic ulcerative colitis |
-
2004
- 2004-09-27 CN CN 200410078380 patent/CN1616041A/en active Pending
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1857453B (en) * | 2006-03-03 | 2010-05-12 | 延边大学 | A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method |
| CN102008565B (en) * | 2009-09-07 | 2012-05-23 | 成都中医药大学 | A kind of pharmaceutical composition for treating ulcerative colitis and preparation method thereof |
| CN102370687A (en) * | 2011-11-17 | 2012-03-14 | 中国中医科学院中医临床基础医学研究所 | Compound Chinese medicinal preparation for treating colonitis and preparation method thereof |
| CN102370687B (en) * | 2011-11-17 | 2017-12-08 | 中国中医科学院中医临床基础医学研究所 | A kind of compound Chinese medicinal preparation for treating colitis and preparation method thereof |
| CN104436088A (en) * | 2013-09-18 | 2015-03-25 | 香港浸会大学 | A kind of Chinese herbal medicine formula for treating inflammatory bowel disease and preparation method thereof |
| CN104436088B (en) * | 2013-09-18 | 2017-10-13 | 香港浸会大学 | Chinese herbal medicine formula for treating inflammatory bowel disease and preparation method thereof |
| CN103893457A (en) * | 2014-03-31 | 2014-07-02 | 王红 | Traditional Chinese medicine for treating ulcerative colitis |
| CN103893457B (en) * | 2014-03-31 | 2018-04-17 | 王红 | One kind treats ulcerative colitis Chinese medicine |
| CN105998264A (en) * | 2016-06-19 | 2016-10-12 | 练燕华 | Traditional Chinese medicine for treating chronic ulcerative colitis |
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