CN112972544B - Traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores and preparation method and application thereof - Google Patents
Traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores and preparation method and application thereof Download PDFInfo
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Abstract
The invention is suitable for the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores as well as a preparation method and application thereof, wherein the traditional Chinese medicine ointment comprises the following components in parts by weight: 2000-3000 parts of animal oil, 20-40 parts of scutellaria baicalensis, 20-40 parts of golden cypress, 20-40 parts of rheum officinale, 20-40 parts of honeysuckle, 20-40 parts of fructus forsythiae, 5-15 parts of radix angelicae, 5-15 parts of sanguisorba officinalis and 5-15 parts of tabellae argyi. The traditional Chinese medicine ointment provided by the embodiment of the invention adopts animal oil as a matrix, has a better moisturizing function, is added with medicines with antiviral effect and the like in modern pharmacological research, can better promote wound recovery and effectively prevent wound infection. The Chinese medicinal ointment can be used for treating burn, scald and pressure sore simultaneously, and has dual purposes. Animal experiments show that the traditional Chinese medicine ointment has remarkable anti-inflammatory and growth promoting effects, and is beneficial to wound recovery and healing.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores as well as a preparation method and application thereof.
Background
The burn and scald ointment is mainly a Meibao moist burn ointment, a Qiangli burn and scald ointment and the like which are commonly used for treating burns and scalds at present, but has the problems of weak scar removing capability, scar remaining after healing and the like. Burn and scald are high in summer, are common to children, teenagers, adults engaged in related industries and the like, and cause a life-long injury problem if improper treatment is carried out in the early stage of burn, so that attention needs to be paid.
The Shanddui Ningqing pressure sore nursing paste with better curative effect on pressure sore in the market has better effect on initial pressure sore, but the same problem is that the Shanddui Ningqing pressure sore nursing paste is not suitable for treating ulceration type pressure sore. Under the social environment that the aging is more serious, the physical function of the old is poor, the skin condition and the living ability are relatively insufficient, and the risk of pressure sores is further increased. The attention degree of pressure sores in China is far less than that of the western countries, and the market of pressure sore paste in the future has great potential.
The burn, scald and pressure sore products are still single, the market space is large, most medical companies have little investment on patients of the type, and the market demand and development are neglected.
Disclosure of Invention
The embodiment of the invention aims to provide a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores and aims to solve the problems in the background art.
The embodiment of the invention is realized in such a way that the traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores comprises the following components in parts by weight: 2000-3000 parts of animal oil, 20-40 parts of scutellaria baicalensis, 20-40 parts of golden cypress, 20-40 parts of rheum officinale, 20-40 parts of honeysuckle, 20-40 parts of fructus forsythiae, 5-15 parts of radix angelicae, 5-15 parts of sanguisorba officinalis and 5-15 parts of tabellae argyi.
As a preferable scheme of the embodiment of the invention, the traditional Chinese medicine ointment comprises the following components in parts by weight: 2200-2800 parts of animal oil, 25-35 parts of scutellaria baicalensis, 25-35 parts of golden cypress, 25-35 parts of rheum officinale, 25-35 parts of honeysuckle, 25-35 parts of fructus forsythiae, 8-12 parts of radix angelicae, 8-12 parts of sanguisorba officinalis and 8-12 parts of tabellae argyi.
As another preferable scheme of the embodiment of the invention, the traditional Chinese medicine ointment comprises the following components in parts by weight: 2400-2600 parts of animal oil, 28-32 parts of scutellaria baicalensis, 28-32 parts of golden cypress, 28-32 parts of rheum officinale, 28-32 parts of honeysuckle, 28-32 parts of fructus forsythiae, 9-11 parts of radix angelicae, 9-11 parts of sanguisorba officinalis and 9-11 parts of blumea balsamifera.
As another preferred aspect of the embodiments of the present invention, the animal oil is lard oil.
Another object of the present invention is to provide a method for preparing the above-mentioned traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, which comprises the following steps:
weighing animal oil, scutellaria baicalensis, golden cypress, rheum officinale, honeysuckle, fructus forsythiae, radix angelicae, garden burnet and blumea balsamifera tablets according to the parts by weight of the components;
pulverizing Scutellariae radix, cortex Phellodendri, radix et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sangusorbae, mixing with animal oil and tabellae Blumeae Preparatum, and making into ointment.
The embodiment of the invention also aims to provide the traditional Chinese medicine ointment prepared by the preparation method.
The other purpose of the embodiment of the invention is to provide an application of the traditional Chinese medicine ointment in preparing medicines for treating burns, scalds and/or pressure sores.
In the embodiment of the invention, when the traditional Chinese medicine ointment is used as burn and scald ointment, the traditional Chinese medicine ointment is suitable for treating diseases such as children's burns caused by hot water and fire, large-area burns and the like, can clear away heat and toxic materials, cool and relieve pain, prevent scalds from foaming in the early clinical period, and can promote skin regeneration, remove rotten meat and the like in the middle and later periods. The traditional Chinese medicine ointment takes animal oil as a substrate, the animal oil is sweet in taste, cool in nature and non-toxic, contains various fatty acids, and has equivalent content of saturated fatty acids and unsaturated fatty acids. Animal oil has been used for treating rhagadia manus et pedis, scrofula, etc. historically, it has also been used as a lipstick or a drug base in addition to being eaten. Scutellariae radix has effects of clearing heat and eliminating dampness, clearing pathogenic fire and removing toxic substance, and stopping bleeding, and can be used for treating acne, ulcer, pressure sore, etc. by external application. Cortex Phellodendri has effects of clearing heat, eliminating dampness, removing toxic substance, and treating sore, and can be used for treating pyocutaneous disease, toxic swelling, eczema, and eczema. Radix et rhizoma Rhei has effects of clearing away damp-heat, purging pathogenic fire, cooling blood, removing blood stasis, and removing toxic substance, and can be used for treating scald due to hot water and fire, upper gastrointestinal hemorrhage, etc. The honeysuckle and the forsythia have the efficacies of clearing away heat and toxic materials, can be used for treating heat-toxin sores and ulcers and the like, and also have the modern pharmacological efficacies of resisting inflammation and the like. Radix Angelicae Dahuricae has effects of subsiding swelling, expelling pus, dispelling pathogenic wind, relieving itching, etc., and can be used for treating acne and tinea, and also has skin caring effect. Sanguisorba root has the effects of cooling blood, stopping bleeding, removing toxicity and healing sores, and can be externally used for treating burns and scalds due to water and fire, carbuncles, swelling, sores and the like. The blumea balsamifera tablet is crystal prepared by extracting fresh leaves of blumea balsamifera of Compositae, has faint scent, and has effects of inducing resuscitation, refreshing mind, clearing heat, and relieving pain, and can be used for treating ear canal suppuration and ulceration by external application. The medicinal powder is adopted to prepare the ointment without using an extract, so that the application of the compatibility theory of the traditional Chinese medicine can be exerted, and the functions of multiple components and multiple targets can be exerted. In addition, the traditional Chinese medicine ointment can be prepared and applied to treating pressure sore and other diseases caused by long-term illness in bed or inconvenient movement, the growth and the diffusion of the pressure sore can be prevented in the early clinical period, and the recovery of the pressure sore and the regeneration of the pressure sore part can be stimulated in the middle and later periods.
Compared with the traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores on the market, the traditional Chinese medicine ointment for treating burns and scalds and/or pressure sores provided by the embodiment of the invention has higher efficiency of treating I-degree and II-degree burns and has little or no scars. The traditional Chinese medicine ointment adopts animal oil as a matrix, has a better moisturizing function, and can better promote wound recovery and effectively prevent wound infection by adding medicines with antiviral effect in modern pharmacological research. When the ointment is used as pressure sore ointment, compared with the common pressure sore ointment on the market, the ointment accords with the principle of the traditional pressure sore treatment, has the characteristics of obvious curative effect, convenient use and the like, and can even be used for treating stage III and stage IV pressure sores. The Chinese medicinal ointment can be used for treating burn, scald and pressure sore simultaneously, and has dual purposes. Animal experiments show that the traditional Chinese medicine ointment has remarkable anti-inflammatory and growth-promoting effects, and is beneficial to wound recovery and healing.
Drawings
FIG. 1 is a diagram showing the therapeutic effect of different scald parts of a child; in fig. 1, a is a graph showing the therapeutic effect of the child's belly, b is a graph showing the therapeutic effect of the leg, and c is a graph showing the therapeutic effect of the foot.
FIG. 2 is a diagram showing the treatment effect of different scald parts of an adult; in fig. 2, a is a graph showing the therapeutic effect of the foot, b is a graph showing the therapeutic effect of the shoulder, and c is a graph showing the therapeutic effect of the leg.
Fig. 3 is a diagram showing the therapeutic effect of the patient with electric burn.
FIG. 4 is a graph of the treatment effect of different parts of a pressure sore patient; in fig. 4, a is a graph showing the therapeutic effect of the caudal vertebra, b is a graph showing the therapeutic effect of the lateral surface of the lower leg, and c is a graph showing the therapeutic effect of the caudal vertebra.
FIG. 5 is an observation view of wound tissues 5d after scalding in different groups of mice; in FIG. 5, a is a model group, b is an administration group, and c is a positive control group.
FIG. 6 is an observation view of wound tissues 10d after scalding of mice of different groups; in FIG. 6, a is a model group, b is an administration group, and c is a positive control group.
FIG. 7 is an observation view of wound tissues of different groups of mice after being scalded for 15 d; in FIG. 7, a is a model group, b is an administration group, and c is a positive control group.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2000g of fresh lard, 40g of scutellaria baicalensis, 40g of golden cypress, 40g of rheum officinale, 40g of honeysuckle, 40g of fructus forsythiae, 15g of radix angelicae, 15g of sanguisorba officinalis and 15g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 2
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 3000g of fresh lard, 20g of scutellaria baicalensis, 20g of golden cypress, 20g of rheum officinale, 20g of honeysuckle, 20g of fructus forsythiae, 5g of radix angelicae, 5g of sanguisorba officinalis and 5g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 3
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2100g of fresh lard, 20g of scutellaria baicalensis, 40g of golden cypress, 20g of rheum officinale, 40g of honeysuckle, 20g of fructus forsythiae, 15g of radix angelicae, 5g of sanguisorba officinalis and 15g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 4
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2900g of fresh lard, 40g of scutellaria baicalensis, 20g of golden cypress, 40g of rheum officinale, 20g of honeysuckle, 40g of fructus forsythiae, 5g of radix angelicae, 15g of sanguisorba officinalis and 5g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 5
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2200g of fresh lard, 35g of scutellaria baicalensis, 35g of golden cypress, 35g of rheum officinale, 35g of honeysuckle, 35g of fructus forsythiae, 12g of radix angelicae, 12g of sanguisorba officinalis and 12g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 6
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2800g of fresh lard, 25g of scutellaria baicalensis, 25g of golden cypress, 25g of rheum officinale, 25g of honeysuckle, 25g of fructus forsythiae, 8g of radix angelicae, 8g of sanguisorba officinalis and 8g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 7
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2300g of fresh lard, 26g of scutellaria baicalensis, 27g of golden cypress, 26g of rheum officinale, 26g of honeysuckle, 26g of fructus forsythiae, 8g of radix angelicae, 12g of sanguisorba officinalis and 8g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 8
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2400g of fresh lard, 32g of scutellaria baicalensis, 32g of golden cypress, 32g of rheum officinale, 32g of honeysuckle, 32g of fructus forsythiae, 11g of radix angelicae, 11g of sanguisorba officinalis and 11g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 9
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2600g of fresh lard, 28g of scutellaria baicalensis, 28g of golden cypress, 28g of rheum officinale, 28g of honeysuckle, 28g of fructus forsythiae, 9g of radix angelicae, 9g of sanguisorba officinalis and 9g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Example 10
The embodiment provides a traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores, and the preparation method comprises the following steps:
s1, weighing 2400-2600 g of fresh lard, 28-32 g of scutellaria baicalensis, 28-32 g of golden cypress, 28-32 g of rheum officinale, 28-32 g of honeysuckle, 28-32 g of fructus forsythiae, 9-11 g of radix angelicae, 9-11 g of sanguisorba officinalis and 9-11 g of tabellae argyi for later use.
S2, pulverizing the weighed radix Scutellariae, cortex Phellodendri, radix Et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sanguisorbae, sieving with No. 8 sieve, mixing with the decocted fresh adeps Sus Domestica and folium Artemisiae Argyi, and making into ointment by conventional method.
Test example:
firstly, the traditional Chinese medicine ointment prepared in the embodiment 10 is used for treating different scald parts of children, and the treatment effect is shown in the attached drawing 1. In fig. 1, a is a graph showing the therapeutic effect of the child's belly, b is a graph showing the therapeutic effect of the leg, and c is a graph showing the therapeutic effect of the foot.
Secondly, the traditional Chinese medicine ointment prepared in the embodiment 10 is used for treating different scald parts of adults, and the treatment effect is shown in the attached figure 2. In fig. 2, a is a graph showing the therapeutic effect of the foot, b is a graph showing the therapeutic effect of the shoulder, and c is a graph showing the therapeutic effect of the leg.
Thirdly, the traditional Chinese medicine ointment prepared in the embodiment 10 is used for treating the patient suffering from the electric burn, and the treatment effect is shown in the attached figure 3.
Fourthly, the traditional Chinese medicine ointment prepared in the embodiment 10 is used for treating different parts of a pressure sore patient, and the treatment effect is shown in the attached figure 4. In fig. 4, a is a graph showing the therapeutic effect of the caudal vertebra, b is a graph showing the therapeutic effect of the lateral surface of the lower leg, and c is a graph showing the therapeutic effect of the caudal vertebra.
Fifthly, animal experiments:
1. the results of the influence of the traditional Chinese medicine ointment prepared in example 10 on the body weight and the activity of the scalded mice are shown in tables 1-2.
In 5 days after the mice are scalded and modeled, the weight average of each group body is obviously increased negatively. The weight average of 10d body is increasing, and the growth rate of the administration group is higher than that of the model group and the administration group, but no obvious difference exists. The weight average of each group is increasing positively, and the weight growth rate among the groups is not obviously different, but is lower than that of the normal group.
TABLE 1 weight gain Rate in mice after Scald
Comparing the data of the model set to the data of the model set,Pless than 0.05; comparing it with the model set,P＜0.01。
after the mice are scalded and modeled, the activity degree is increased to a certain extent within 5d, but no obvious difference is generated between the mice and normal groups. And 15d, the activity of each group is reduced, and the data are not statistically different compared with the normal group.
TABLE 2 post-scald mouse liveness
2. The effect result of the traditional Chinese medicine ointment prepared in the embodiment 10 on the healing of the wound surface of the scalded mouse is as follows:
wound tissues are respectively taken for observation at 5d, 10d and 15d after the mouse is scalded, and the observation is shown in figures 5-7. At 5d, the model group and the positive control group have obvious subcutaneous congestion and adhesion, and the administration group has no obvious subcutaneous congestion and adhesion. The wound of the 10d mouse has blood scab, the blood scab of the administration group is easy to separate, and the blood scab of the model group and the positive control group has canker below and is not easy to separate from tissues. One wound of the mice in the 15d administration group is completely healed, no congestion exists in the subcutaneous part, and subcutaneous congestion still exists in the administration group and the positive control group.
The first wound healing rate determination is carried out 5 days after the mice are scalded, the wound surfaces of the model group and the positive control group are enlarged, and the wound is generatedThe surface healing rate is negative, the wound surface of the administration group is reduced, the healing rate is positive, and the surface healing rate is very different from that of the model group (A)P< 0.01). The healing rate of the wound surface of each group 10d and 15d is increased along with time, and no significant difference exists among the groups (the specific result is shown in table 3).
TABLE 3 mouse wound healing Rate after Scald
Comparing the data of the model set to the data of the model set,Pless than 0.05; comparing with the model group,P＜0.01。
after 5d, 10d and 15d of the scald of the mouse, the scald wound is taken to determine the VEGF content, the 3 times of measurement values of the positive control group are higher than those of the model group and the administration group, and the difference is not significant (the specific result is shown in Table 4).
TABLE 4 mouse wound VEGF content after Scald
3. The influence of the traditional Chinese medicine ointment prepared in the embodiment 10 on the inflammatory reaction of the scalded mice is as follows:
mice 5d and 10d after scald are subjected to blood serum IL-1 and TNF-αThe content was measured, and as shown in tables 5 to 6, there was no significant difference between the groups. 15d the serum IL-1 content of the administration group is lower than that of the model group, and the difference is very obvious (P< 0.01); serum TNF-αThe content is lower than that of the model group and the positive control group, and the difference is obvious (P＜0.05）。
TABLE 5 post-scald IL-1 content in serum of mice
Comparing the data of the model set to the data of the model set,Pless than 0.05; comparing it with the model set,P＜0.01。
TABLE 6 mice serum TNF-αContent (wt.)
Comparing the data of the model set to the data of the model set,Pless than 0.05; comparing it with the model set,Pis less than 0.01; the delta is compared with that of the positive control group,P＜0.05。
furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (4)
1. The traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores is characterized by being prepared from the following components in parts by weight: 2400-2600 parts of animal oil, 28-32 parts of scutellaria baicalensis, 28-32 parts of golden cypress, 28-32 parts of rheum officinale, 28-32 parts of honeysuckle, 28-32 parts of fructus forsythiae, 9-11 parts of radix angelicae, 9-11 parts of sanguisorba officinalis and 9-11 parts of blumea balsamifera; the animal oil is lard oil.
2. A method for preparing the traditional Chinese medicine ointment for treating burns, scalds and/or pressure sores as claimed in claim 1, which is characterized by comprising the following steps:
weighing animal oil, scutellaria baicalensis, golden cypress, rheum officinale, honeysuckle, fructus forsythiae, radix angelicae, garden burnet and blumea balsamifera tablets according to the parts by weight of the components;
pulverizing Scutellariae radix, cortex Phellodendri, radix et rhizoma Rhei, flos Lonicerae, fructus forsythiae, radix Angelicae Dahuricae, and radix Sangusorbae, mixing with animal oil and tabellae Blumeae Preparatum, and making into ointment.
3. A Chinese medicinal ointment prepared by the preparation method of claim 2.
4. Use of a traditional Chinese medicine ointment as defined in any one of claims 1 and 3 for the preparation of a medicament for the treatment of burns and scalds and/or pressure sores.
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| CN106581241A (en) * | 2015-10-15 | 2017-04-26 | 吴志锋 | Burn and scald treating traditional Chinese medicine composition |
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