CN112569326A - Traditional Chinese medicine composition for treating costalgia and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating costalgia, and relates to the technical field of traditional Chinese medicines. In the invention, the traditional Chinese medicine composition comprises the following traditional Chinese medicine components: mirabilite, longhairy antenoron herb, weeping forsythia, dandelion, turmeric root-tuber, cape jasmine fruit, virgate wormwood herb, giant knotweed rhizome, rhubarb, barbed skullcap herb, Chinese thorowax root, abrus cantoniensis hance, immature bitter orange, szechwan chinaberry fruit and corydalis tuber. The traditional Chinese medicine composition has the advantages of convenience in preparation and taking, safety and no side effect, and is an optimal traditional Chinese medicine preparation for treating the costalgia with excessive heat in liver and gallbladder proved by examination in long-term diagnosis and treatment practice.

Description

Traditional Chinese medicine composition for treating costalgia and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating costalgia and a preparation method thereof.

Background

Hypochondriac pain (hypochondriac pain) is a disease mainly manifested by pain in one or both lateral flanks, and is also a common subjective symptom clinically. The hypochondrium, the lateral chest of the finger, is the general term from the axilla to the twelfth costal region. The hypochondriac pain causes a lot of damage to the body and life of the patient.

Currently, hypochondriac pain is generally thought to be caused by four reasons:

first, long-term overnight leads to different degrees of rib pain. The pain feeling under ribs can be caused to different degrees when people stay up for a long time, and the liver of a patient is overloaded and the health of the patient can be influenced to different degrees because the viscera of the patient are greatly damaged by long-time fatigue;

secondly, the diet is irregular for a long time. In normal times, the gastrointestinal dysfunction of a patient can be caused by careless diet, the liver and gall bladder can be infected, once fatty liver is suffered, the fatty liver is not treated completely, and rib pain can be caused easily after long-time irregular diet;

thirdly, rib pain is caused by depression. Depression or anxiety disorder are diseases in the aspect of nervous system, and the internal cardiac pressure of some patients is too high or the mood of some patients is not good for a long time, so that pain feeling of unilateral ribs can be caused, long-time depression or emotional depression has great influence on the health of people, the venation is blocked, or unsmooth economic operation is caused, and the feeling of local pain is caused;

fourthly, chronic diseases induce costal pain. The causes of rib pain are complex, rib pain is caused by infection of adjacent organs or diseases of a certain aspect, local edema is caused by liver diseases or inflammation infection of costal cartilage, and rib pain and body weakness of a patient can be caused.

However, at present, there is no agent that simply treats this condition.

Disclosure of Invention

The invention provides a traditional Chinese medicine composition for treating costalgia and a preparation method thereof, and aims to solve the problems in the background art.

In order to achieve the technical purpose, the invention adopts the following technical scheme:

the traditional Chinese medicine composition for treating costalgia is characterized by comprising the following traditional Chinese medicine components: mirabilite, longhairy antenoron herb, weeping forsythia, dandelion, turmeric root-tuber, cape jasmine fruit, virgate wormwood herb, giant knotweed rhizome, rhubarb, barbed skullcap herb, Chinese thorowax root, abrus cantoniensis hance, immature bitter orange, szechwan chinaberry fruit and corydalis tuber.

Preferably, the weight ratio of the traditional Chinese medicine components is as follows: 50-100 parts of mirabilite, 100-150 parts of lysimachia, 40-80 parts of fructus forsythiae, 50-100 parts of dandelion, 50-100 parts of radix curcumae, 40-80 parts of gardenia, 50-100 parts of oriental wormwood, 40-80 parts of polygonum cuspidatum, 15-50 parts of rheum officinale, 30-70 parts of sculellaria barbata, 30-70 parts of radix bupleuri, 40-80 parts of abrus cantoniensis hance, 40-80 parts of immature bitter orange, 40-80 parts of szechwan chinaberry fruit and 30-70 parts of rhizoma corydalis.

Preferably, the weight ratio of the traditional Chinese medicine components is as follows: 70-80 parts of mirabilite, 135 parts of desmodium 115-containing materials, 55-70 parts of fructus forsythiae, 70-80 parts of dandelion, 70-80 parts of radix curcumae, 55-70 parts of gardenia, 70-80 parts of oriental wormwood, 55-70 parts of polygonum cuspidatum, 30-45 parts of rheum officinale, 40-60 parts of sculellaria barbata, 40-60 parts of radix bupleuri, 55-70 parts of abrus cantoniensis hance, 55-70 parts of immature bitter orange, 55-70 parts of szechwan chinaberry fruit and 40-60 parts of rhizoma corydalis.

Preferably, the weight ratio of the traditional Chinese medicine components is as follows: 76 parts of mirabilite, 127 parts of desmodium, 63 parts of fructus forsythiae, 76 parts of dandelion, 76 parts of radix curcumae, 63 parts of gardenia, 76 parts of oriental wormwood, 63 parts of giant knotweed, 38 parts of rheum officinale, 51 parts of barbed skullcap herb, 51 parts of radix bupleuri, 63 parts of abrus cantoniensis hance, 63 parts of immature bitter orange, 63 parts of szechwan chinaberry fruit and 51 parts of corydalis tuber.

The mirabilite in the traditional Chinese medicine composition is crystal prepared by processing and refining sulfate mineral mirabilite family mirabilite. Sodium sulfate (Na) mainly containing water₂SO₄·10H₂O). The distribution is distributed in most areas of the country. Has the effects of relaxing bowels with purgative, moistening dryness, softening hard masses, clearing away fire and relieving swelling. It is often used for treating excess heat accumulation, abdominal distention and pain, constipation, and intestinal abscess with swelling and pain; it is indicated for acute mastitis, hemorrhoid with swelling and pain.

The herba Lysimachiae Christinae is fresh or dried whole plant of Lysimachia christinae Hance of Lysimachia of Primulaceae, such as Lysimachia christinae Hance, herba Desmodii Styracifolii, herba Lysimachiae Christinae, herba Lobeliae chinensis, radix rehmanniae, etc. Lysimachia christinae Hance is bitter, sour and slightly cold in taste. It enters liver, gallbladder, kidney and bladder meridians. Has the functions of clearing away heat and toxic material, promoting urination, removing urinary calculus, promoting blood circulation and dissipating blood stasis. Can be used for treating liver and gall calculus, cholecystitis, icterohepatitis, urinary calculus, edema, traumatic injury, venomous snake bite, and muscarine and drug poisoning; it is used externally to treat suppurative inflammation, burn and scald.

Fructus forsythiae is shrub deciduous in Forsythia of Oleaceae of twisted order of dicotyledons. Enter heart, liver and gallbladder meridians. Has the functions of clearing away heat and toxic material, dispersing accumulation of pathogen and eliminating swelling. It is indicated for warm heat, erysipelas, macula, superficial infection, abscess, swelling, scrofula and stranguria.

Dandelion is sweet in nature and taste, slightly bitter and cold. It enters liver and stomach meridians. Has diuretic, laxative, jaundice treating, and gallbladder promoting effects. It is used to treat heat-toxin, carbuncle, pyocutaneous disease, internal carbuncle, conjunctival congestion, swelling and pain, damp-heat, jaundice, stranguria with urine, furuncle, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, pulmonary abscess, intestinal abscess, damp-heat jaundice, and stranguria with pain.

The radix Curcumae is dried root tuber of Curcuma wenyujin Y, H.Chenet C.Ling, Curcuma longa LongaL, Curcuma kwangtungakwangsiensis S.G.Lee et C.F.Liang or Curcuma zedoaria phareocauli Val. Pungent and fragrant but not drastic, ascending first and descending second, entering heart and enveloping. For blood-qi-heart-abdominal pain, postpartum septicemia, heart-attacking and dying, heart-fire-attacking and venomous diseases.

Gardenia jasminoides is the fruit of Gardenia jasminoides Ellis of Rubiaceae. The fruit of gardenia is a traditional Chinese medicine, belongs to the first batch of medical and edible dual-purpose resources issued by the Ministry of health, and has the functions of protecting liver, benefiting gallbladder, reducing blood pressure, calming, stopping bleeding, reducing swelling and the like.

Herba Artemisiae Scopariae is a semi-shrub-like herbaceous plant of Artemisia of Compositae, and the plant has strong fragrance. Is rich in vitamins, multiple trace elements and more than 20 amino acids, and has good health promoting effect.

Giant knotweed (academic name: Reynoutria japonica Houtt.): polygonaceae, Polygonum perennial herb. The rhizome is used for medicine, and has the effects of promoting blood circulation, removing blood stasis, dredging channels, relieving cough, etc.

The radix et rhizoma Rhei is derived from dried root and rhizome of Rheum palmatum L, Rheum officinale Baill, Rheum officinale Kitag et al, Rheum tanguticum Maxim. ex Balf. Has effects in removing food stagnation, clearing away heat and dampness, purging pathogenic fire, cooling blood, removing blood stasis, and removing toxic materials.

The scientific name of barbed skullcap: scutellaria barbata d.don) (the plant material of Jiangsu province), which is called: stringy exterior syndrome (Sichuan Chengdu), thin baikal skullcap root (Sichuan Puge), tooth-brush grass (Jiangsu Suzhou), Tianji grass (Jiangsu Yixing), Shuichu baikal skullcap root (Jiangsu Nanjing), and Han Xin grass (Guangzhou plant). Is a perennial herb of the genus Scutellaria of the family Labiatae. The herba Scutellariae Barbatae has effects in clearing away heat and toxic materials, promoting blood circulation, dispelling blood stasis, relieving swelling and pain, and resisting cancer. Is cold in nature and sour in taste, and the whole herb contains various vitamins, trace elements, amino acids and other components. Has the effects of cooling blood, removing toxic substances, removing blood stasis, relieving pain, relieving swelling, clearing heat and promoting diuresis.

Chaihu is a herb recorded in the Chinese pharmacopoeia, and the medicinal part is the dry root of Bupleurum chinense or Bupleurum scorzonerifolium of Umbelliferae. Collected in spring and autumn, removed stems and leaves and silt, and dried. Bupleurum root, radix bupleuri is a commonly used exterior syndrome relieving drug. Is also called as Diwu, potherb mustard, mushroom grass and firewood, is bitter in nature and taste, slightly cold, and enters liver and gallbladder meridians. Has the functions of harmonizing exterior and interior, soothing liver and invigorating yang.

The herba abri is dried whole plant of Abrus cantoniensis of Leguminosae. Sweet, slightly bitter and cool. Has the functions of eliminating dampness and jaundice, clearing away heat and toxic material, soothing liver and relieving pain. It is commonly indicated for damp-heat yellow abscess, uncomfortable hypochondriac region, distending pain in stomach, and mammary abscess with swelling pain.

The fructus Aurantii Immaturus is Rutaceae plant Citrus aurantium L. and its cultivar or dried young fruit of Citrus sinensis Osbeck. Can be used for treating stagnation, abdominal distention, pain, dysentery, constipation, phlegm stagnation, qi stagnation, thoracic obstruction, and viscera prolapse.

The fructus Toosendan is dried mature fruit of Melia toosendan Sieb. Can be used for treating liver depression, pathogenic fire, distending pain of chest, hypochondrium, abdominal cavity, hernia pain, and abdominal pain due to parasitic infestation.

Corydalis yanhusuo (Y.H.Chou & Chun C.Hsu) W.T.Wang ex Z.Y.Su & C.Y.Wu) is a perennial herb of the family Papaveraceae, the genus Viola. The corydalis tuber is used as a medicine and has the functions of promoting blood circulation, removing blood stasis, promoting qi circulation and relieving pain.

In the present invention, the costalgia is a costalgia due to excessive heat of the liver and gallbladder.

The invention discloses application of a traditional Chinese medicine composition for treating costalgia in treating costalgia due to excessive heat of liver and gallbladder.

Preferably, in the invention, the traditional Chinese medicine composition is a water pill.

The invention further provides a method for preparing the traditional Chinese medicine composition for treating costalgia, which comprises the following steps:

s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.

Compared with the prior art, the invention has the beneficial effects that: the traditional Chinese medicine composition has the advantages of convenience in preparation and taking, safety and no side effect, and is an optimal traditional Chinese medicine preparation for treating the costalgia with excessive heat in liver and gallbladder proved by examination in long-term diagnosis and treatment practice.

Detailed Description

The present invention will be described in further detail with reference to the following examples, which are not intended to limit the invention thereto.

Example 1

50g of mirabilite, 100g of desmodium, 40g of fructus forsythiae, 50g of dandelion, 50g of radix curcumae, 40g of fructus gardeniae, 50g of oriental wormwood, 40g of giant knotweed rhizome, 15g of rheum officinale, 30g of barbed skullcap herb, 30g of radix bupleuri, 40g of abrus cantoniensis hance, 40g of immature bitter orange, 40g of szechwan chinaberry fruit and 30g of rhizoma corydalis.

The preparation of the water pill comprises the following steps:

s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.

Example 2

70g of mirabilite, 115g of desmodium, 55g of fructus forsythiae, 70g of dandelion, 70g of radix curcumae, 55g of fructus gardeniae, 70g of oriental wormwood, 55g of polygonum cuspidatum, 30g of rheum officinale, 40g of sculellaria barbata, 40g of radix bupleuri, 55g of abrus cantoniensis hance, 55g of immature bitter orange, 55g of szechwan chinaberry fruit and 40g of rhizoma corydalis.

The preparation of the water pill comprises the following steps:

s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.

Example 3

76g of mirabilite, 127g of desmodium, 63g of fructus forsythiae, 76g of dandelion, 76g of radix curcumae, 63g of gardenia, 76g of oriental wormwood, 63g of giant knotweed, 38g of rheum officinale, 51g of barbed skullcap herb, 51g of radix bupleuri, 63g of abrus cantoniensis hance, 63g of immature bitter orange, 63g of szechwan chinaberry fruit and 51g of rhizoma corydalis.

The preparation of the water pill comprises the following steps:

s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.

Example 4

80g of mirabilite, 135g of desmodium, 70g of fructus forsythiae, 80g of dandelion, 80g of radix curcumae, 70g of fructus gardeniae, 80g of oriental wormwood, 70g of giant knotweed, 45g of rheum officinale, 60g of barbed skullcap herb, 60g of radix bupleuri, 70g of abrus cantoniensis hance, 70g of immature bitter orange, 70g of szechwan chinaberry fruit and 60g of rhizoma corydalis.

The preparation of the water pill comprises the following steps:

s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.

Example 5

100g of mirabilite, 150g of desmodium, 80g of fructus forsythiae, 100g of dandelion, 100g of radix curcumae, 80g of fructus gardeniae, 100g of oriental wormwood, 80g of giant knotweed, 50g of rheum officinale, 70g of sculellaria barbata, 70g of radix bupleuri, 80g of abrus cantoniensis hance, 80g of immature bitter orange, 80g of szechwan chinaberry fruit and 70g of rhizoma corydalis.

The preparation of the water pill comprises the following steps:

s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.

Test example 1

And (4) checking: the pills prepared by the implementation 1-5 meet the requirements of pharmacopoeia by checking the standards under the pill items specified in pharmacopoeia of the people's republic of China 2015 edition.

Comparative example 1

30 patients with costalgia were selected, and were randomized and divided into three groups on average. Mecobalamin tablets (1 tablet at a time and three times per day in 1 day) and the traditional Chinese medicine composition (example 3, three times per day and 10 tablets at a time) of the invention were administered separately for two weeks without any other medicine and acupuncture treatment.

Symptom scoring criteria:

1 minute: the symptoms are light, and life and work are not affected;

and 2, dividing: severe symptoms, affecting life and work, but can be tolerated;

and 3, dividing: the symptoms are serious, normal life and work cannot be realized, and the patient cannot tolerate the symptoms.

The severity can be further expressed by taking a decimal number between 1 and 3.

Score before and after each group treatment (mean. + -. s)

	Mecobalamin tablets	The Chinese medicinal composition of the invention
			Before treatment	2.82±0.37	2.84±0.41
After treatment	2.15±0.24	1.23±0.19

As can be seen from the above table, the Chinese medicinal composition has more obvious actual clinical effect and is superior to mecobalamin tablets for nourishing nerves.

Typical clinical cases are:

the cases are as follows: patient female, 56 years old, complaining of symptoms: costalgia, bitter taste in mouth, irritability of gallbladder wall through B-ultrasonic examination, and unobvious effect when various medicines are taken. After the application of the applicant, after the traditional Chinese medicine composition is taken for 3 days, bitter taste symptom disappears, costalgia symptom disappears after 7 days, and gallbladder wall is recovered after 14 days through B ultrasonic examination.

The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It should be noted that, for a person skilled in the art, several modifications and refinements can be made without departing from the basic principle of the invention, and these modifications and refinements are also considered to be within the protective scope of the invention.

Claims (8)

1. The traditional Chinese medicine composition for treating costalgia is characterized by comprising the following traditional Chinese medicine components: mirabilite, longhairy antenoron herb, weeping forsythia, dandelion, turmeric root-tuber, cape jasmine fruit, virgate wormwood herb, giant knotweed rhizome, rhubarb, barbed skullcap herb, Chinese thorowax root, abrus cantoniensis hance, immature bitter orange, szechwan chinaberry fruit and corydalis tuber.

2. The traditional Chinese medicine composition for treating costalgia according to claim 1, wherein the weight ratio of the traditional Chinese medicine components is as follows: 50-100 parts of mirabilite, 100-150 parts of lysimachia, 40-80 parts of fructus forsythiae, 50-100 parts of dandelion, 50-100 parts of radix curcumae, 40-80 parts of gardenia, 50-100 parts of oriental wormwood, 40-80 parts of polygonum cuspidatum, 15-50 parts of rheum officinale, 30-70 parts of sculellaria barbata, 30-70 parts of radix bupleuri, 40-80 parts of abrus cantoniensis hance, 40-80 parts of immature bitter orange, 40-80 parts of szechwan chinaberry fruit and 30-70 parts of rhizoma corydalis.

3. The traditional Chinese medicine composition for treating costalgia according to claim 2, wherein the weight ratio of the traditional Chinese medicine components is as follows: 70-80 parts of mirabilite, 135 parts of desmodium 115-containing materials, 55-70 parts of fructus forsythiae, 70-80 parts of dandelion, 70-80 parts of radix curcumae, 55-70 parts of gardenia, 70-80 parts of oriental wormwood, 55-70 parts of polygonum cuspidatum, 30-45 parts of rheum officinale, 40-60 parts of sculellaria barbata, 40-60 parts of radix bupleuri, 55-70 parts of abrus cantoniensis hance, 55-70 parts of immature bitter orange, 55-70 parts of szechwan chinaberry fruit and 40-60 parts of rhizoma corydalis.

4. The traditional Chinese medicine composition for treating costalgia according to claim 3, wherein the weight ratio of the traditional Chinese medicine components is as follows: 76 parts of mirabilite, 127 parts of desmodium, 63 parts of fructus forsythiae, 76 parts of dandelion, 76 parts of radix curcumae, 63 parts of gardenia, 76 parts of oriental wormwood, 63 parts of giant knotweed, 38 parts of rheum officinale, 51 parts of barbed skullcap herb, 51 parts of radix bupleuri, 63 parts of abrus cantoniensis hance, 63 parts of immature bitter orange, 63 parts of szechwan chinaberry fruit and 51 parts of corydalis tuber.

5. The traditional Chinese medicine composition for treating costalgia according to any one of claims 1 to 4, wherein: the costalgia refers to costalgia caused by excessive heat of liver and gallbladder.

6. The use of the traditional Chinese medicine composition for treating costalgia according to claim 5 in treating costalgia with excess heat in liver and gallbladder.

7. The traditional Chinese medicine composition for treating costalgia according to any one of claims 1 to 6, wherein: the traditional Chinese medicine composition is a water pill.

8. A method of preparing the traditional Chinese medicine composition for treating costalgia of claim 7, comprising the steps of: s1 weighing: weighing the traditional Chinese medicine components according to the weight ratio;

s2 crushing: respectively crushing the weighed traditional Chinese medicine components, and sieving the crushed traditional Chinese medicine components with a 100-mesh sieve to obtain raw medicinal powder;

s3 mixing: mixing the above medicinal powders;

s4 strip-forming and pill-making: adding purified water into the raw material powder of S3 according to the proportion of 1: 1.2-1.5, fully stirring, and manually kneading into a lump; uniformly cutting the medicinal mass into blocks, rubbing into strips, and cutting into pills to obtain vegetarian pills;

s5 pelleting: and (4) polishing, drying and airing the vegetarian pills obtained in the step (S4) to obtain finished products, wherein each 10 pills are 1.0 g in weight.