CN112220876A - Medicinal moxibustion traditional Chinese medicine and preparation method thereof - Google Patents
Medicinal moxibustion traditional Chinese medicine and preparation method thereof Download PDFInfo
- Publication number
- CN112220876A CN112220876A CN202011285476.6A CN202011285476A CN112220876A CN 112220876 A CN112220876 A CN 112220876A CN 202011285476 A CN202011285476 A CN 202011285476A CN 112220876 A CN112220876 A CN 112220876A
- Authority
- CN
- China
- Prior art keywords
- parts
- prescription
- prepared
- moxibustion
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 46
- 238000002360 preparation method Methods 0.000 title claims description 17
- 239000000203 mixture Substances 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims abstract description 14
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 12
- 230000001543 purgative effect Effects 0.000 claims abstract description 12
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229940116229 borneol Drugs 0.000 claims abstract description 11
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 11
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000008141 laxative Substances 0.000 claims abstract description 11
- 238000010926 purge Methods 0.000 claims abstract description 11
- 244000197580 Poria cocos Species 0.000 claims abstract description 10
- 235000008599 Poria cocos Nutrition 0.000 claims abstract description 10
- 241001522129 Pinellia Species 0.000 claims abstract description 9
- 241000007126 Codonopsis pilosula Species 0.000 claims abstract description 6
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 6
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 6
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 6
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 6
- 235000006533 astragalus Nutrition 0.000 claims abstract description 6
- 244000131316 Panax pseudoginseng Species 0.000 claims abstract description 5
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims abstract description 5
- 241000405414 Rehmannia Species 0.000 claims abstract description 5
- 241000045403 Astragalus propinquus Species 0.000 claims abstract description 3
- 240000006766 Cornus mas Species 0.000 claims abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- 239000000463 material Substances 0.000 claims description 25
- 238000000227 grinding Methods 0.000 claims description 15
- 241001106462 Ulmus Species 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 14
- 239000002245 particle Substances 0.000 claims description 14
- 239000000843 powder Substances 0.000 claims description 14
- 238000003756 stirring Methods 0.000 claims description 13
- 230000009471 action Effects 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 7
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 5
- 241000180649 Panax notoginseng Species 0.000 claims description 5
- 241000227129 Aconitum Species 0.000 claims description 4
- 241001061264 Astragalus Species 0.000 claims description 3
- 235000001188 Peltandra virginica Nutrition 0.000 claims description 3
- 210000004233 talus Anatomy 0.000 claims description 3
- 208000002193 Pain Diseases 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 7
- 210000004369 blood Anatomy 0.000 abstract description 7
- 230000001717 pathogenic effect Effects 0.000 abstract description 7
- 208000024891 symptom Diseases 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 238000010792 warming Methods 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 5
- 230000003014 reinforcing effect Effects 0.000 abstract description 5
- 230000000638 stimulation Effects 0.000 abstract description 5
- 230000001225 therapeutic effect Effects 0.000 abstract description 4
- 241000173529 Aconitum napellus Species 0.000 abstract description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract description 2
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 208000003455 anaphylaxis Diseases 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 210000003205 muscle Anatomy 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 41
- 208000011580 syndromic disease Diseases 0.000 description 13
- 208000004998 Abdominal Pain Diseases 0.000 description 8
- 241000699670 Mus sp. Species 0.000 description 8
- 208000031971 Yin Deficiency Diseases 0.000 description 8
- 229940079593 drug Drugs 0.000 description 8
- 238000001467 acupuncture Methods 0.000 description 7
- 210000003734 kidney Anatomy 0.000 description 7
- 238000002485 combustion reaction Methods 0.000 description 6
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 230000008093 supporting effect Effects 0.000 description 6
- 206010013935 Dysmenorrhoea Diseases 0.000 description 5
- 241000699666 Mus <mouse, genus> Species 0.000 description 5
- 210000001015 abdomen Anatomy 0.000 description 5
- 238000003825 pressing Methods 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 5
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 4
- 230000036541 health Effects 0.000 description 4
- 235000008216 herbs Nutrition 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 230000003821 menstrual periods Effects 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 235000015961 tonic Nutrition 0.000 description 4
- 230000001256 tonic effect Effects 0.000 description 4
- 229960000716 tonics Drugs 0.000 description 4
- 241001391944 Commicarpus scandens Species 0.000 description 3
- 241000209020 Cornus Species 0.000 description 3
- 208000004880 Polyuria Diseases 0.000 description 3
- 208000031975 Yang Deficiency Diseases 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 230000027758 ovulation cycle Effects 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 229940126680 traditional chinese medicines Drugs 0.000 description 3
- 210000001113 umbilicus Anatomy 0.000 description 3
- 206010067484 Adverse reaction Diseases 0.000 description 2
- 206010008479 Chest Pain Diseases 0.000 description 2
- 206010010071 Coma Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010012218 Delirium Diseases 0.000 description 2
- 206010013954 Dysphoria Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 208000029082 Pelvic Inflammatory Disease Diseases 0.000 description 2
- 241001619461 Poria <basidiomycete fungus> Species 0.000 description 2
- 206010057071 Rectal tenesmus Diseases 0.000 description 2
- 230000006838 adverse reaction Effects 0.000 description 2
- 230000000172 allergic effect Effects 0.000 description 2
- 208000010668 atopic eczema Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 206010013990 dysuria Diseases 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000001939 inductive effect Effects 0.000 description 2
- 238000010409 ironing Methods 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 238000000554 physical therapy Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 239000002893 slag Substances 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 230000001502 supplementing effect Effects 0.000 description 2
- 208000012271 tenesmus Diseases 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- UIAGMCDKSXEBJQ-IBGZPJMESA-N 3-o-(2-methoxyethyl) 5-o-propan-2-yl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1C1=CC=CC([N+]([O-])=O)=C1 UIAGMCDKSXEBJQ-IBGZPJMESA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010000097 Abdominal tenderness Diseases 0.000 description 1
- 241000233788 Arecaceae Species 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 201000009273 Endometriosis Diseases 0.000 description 1
- 239000009636 Huang Qi Substances 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 208000037093 Menstruation Disturbances Diseases 0.000 description 1
- 206010027339 Menstruation irregular Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010041956 Stasis syndrome Diseases 0.000 description 1
- 238000000692 Student's t-test Methods 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 206010046798 Uterine leiomyoma Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 229940023019 aconite Drugs 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 231100000460 acute oral toxicity Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000004883 areola Anatomy 0.000 description 1
- 208000005634 blind loop syndrome Diseases 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003610 charcoal Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 208000010643 digestive system disease Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 208000017561 flaccidity Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 231100000037 inhalation toxicity test Toxicity 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 229960000715 nimodipine Drugs 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000002611 ovarian Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 208000017443 reproductive system disease Diseases 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 238000009602 toxicology test Methods 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a medicinal moxibustion traditional Chinese medicine, which consists of a tonifying prescription and a purging prescription, wherein the tonifying prescription is prepared from the following components in parts by weight: 5-10 parts of dogwood, 5-10 parts of prepared rehmannia root, 5-10 parts of Chinese yam, 5-10 parts of astragalus membranaceus, 5-10 parts of codonopsis pilosula and 5-10 parts of prepared monkshood; the purgative prescription is prepared from the following components in parts by weight: 5-10 parts of poria cocos, 5-10 parts of cortex moutan, 5-10 parts of rhizoma alismatis, 5-10 parts of pinellia ternate, 2.5-5 parts of pseudo-ginseng and 2.5-5 parts of borneol. A method for preparing Chinese medicinal moxibustion strip comprises preparing moxibustion strip from reinforcing formula and purging formula respectively. The application has the following beneficial effects: the traditional Chinese medicine composition can be flexibly selected according to different symptoms and constitutions, can be used in a dialectical manner, naturally emits heat through scientific compatibility, is strong in permeation, does not have any stimulation or discomfort, and does not cause anaphylactic reaction; moderate heat, and has good therapeutic effects of warming muscle, dispelling cold, dispelling pathogenic wind, eliminating dampness, promoting qi and blood circulation, warming and dredging collaterals, promoting blood circulation for removing blood stasis, and relieving pain by permeating into channels and collaterals through transdermal absorption.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine physiotherapy and health care, in particular to a traditional Chinese medicine for moxibustion and a preparation method thereof.
Background
Acupuncture is a method of preventing and treating diseases by acupuncture and moxibustion. The acupuncture therapy is to insert a metal needle into a certain acupoint of a human body, and to adjust nutrient, defensive and qi and blood by applying manipulations; moxibustion is achieved by rubbing moxa into moxa sticks or moxa cones, and igniting the moxa sticks to warm the skin surface of acupuncture points, thereby warming and dredging channels and collaterals and harmonizing qi and blood.
Moxibustion therapy is that moxa or other medicines are placed on acupuncture points of the body surface for burning and warm-pressing, and by virtue of the mild heat of moxibustion fire and the action of medicines, the moxibustion therapy has the effects of warming and activating qi and blood, strengthening body resistance and eliminating pathogenic factors through the conduction of meridians and collaterals, thereby achieving the purposes of treating diseases, preventing diseases and protecting health.
In the prior art, a single moxa only has the stimulation effects of acupoint burning and warm ironing, and although the moxa has a certain health-care curative effect, the effect needs to be improved. The medicinal moxibustion strip prepared from other traditional Chinese medicine components has complex formula components, poor pertinence and unreasonable curative effect, or has too simple formula components, and is restricted to adapt to constitutional symptoms. In addition, the existing moxibustion stick has the defects of poor toughness, easy scattering of powder slag and breakage, high combustion speed and difficult control.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a medicinal moxibustion traditional Chinese medicine which can be selected for use according to symptoms, is not easy to break and drop slag, has long burning time, more obvious stimulation of burning and warm ironing and has obvious health care and physical therapy effects.
The invention also aims to provide a preparation method of the medicinal moxibustion traditional Chinese medicine.
In order to achieve the purpose, the technical scheme of the invention is as follows: a traditional Chinese medicine for moxibustion consists of a tonifying prescription and a purging prescription, wherein the tonifying prescription is prepared from the following components in parts by weight: 5-10 parts of dogwood, 5-10 parts of prepared rehmannia root, 5-10 parts of Chinese yam, 5-10 parts of astragalus membranaceus, 5-10 parts of codonopsis pilosula and 5-10 parts of prepared monkshood;
the purgative prescription is prepared from the following components in parts by weight: 5-10 parts of poria cocos, 5-10 parts of cortex moutan, 5-10 parts of rhizoma alismatis, 5-10 parts of pinellia ternate, 2.5-5 parts of pseudo-ginseng and 2.5-5 parts of borneol.
Preferably, the medicinal moxibustion traditional Chinese medicine consists of a tonifying prescription and a purging prescription, wherein the tonifying prescription is prepared from the following components in parts by weight: 6-8 parts of dogwood, 6-8 parts of prepared rehmannia root, 6-8 parts of Chinese yam, 6-8 parts of astragalus, 6-8 parts of codonopsis pilosula and 6-8 parts of prepared monkshood;
the purgative formula is prepared from the following components in parts by weight: 6-8 parts of poria cocos, 6-8 parts of cortex moutan, 6-8 parts of rhizoma alismatis, 6-8 parts of pinellia ternate, 3-4 parts of pseudo-ginseng and 3-4 parts of borneol.
A preparation method of a medicinal moxibustion traditional Chinese medicine comprises preparing a reinforcing formula and a purgative formula into moxibustion sticks respectively, wherein the preparation method of the reinforcing formula comprises the following steps:
(1) material preparation and grinding: grinding and crushing the components respectively until the particle size is 85-110 meshes; then uniformly mixing all the components to form a mixture;
(2) mixing and stirring: adding 50-75% ethanol solution into the mixture, wherein the addition amount of the ethanol solution is 40-55% of the total weight of the mixture, and stirring at the rotating speed of 80-100rpm for 20-50 minutes per minute to form a wet material;
(3) hydraulic forming: putting the wet material into a tubular mold, and applying 85-115 tons of pressure to press and mold under the action of ultrasonic waves;
(4) drying: baking at 40-45 deg.C for 30-60 min.
The preparation method of the purgative prescription comprises the following steps:
(1) material preparation and grinding: respectively grinding and crushing the tuckahoe, the cortex moutan, the rhizoma alismatis, the pinellia ternate and the panax notoginseng until the particle size is 85-110 meshes, and grinding and crushing the borneol until the particle size is 120-180 meshes; then uniformly mixing all the components to form a mixture;
(2) mixing and stirring: adding 50-75% ethanol solution into the mixture, wherein the addition amount of the ethanol solution is 40-55% of the total weight of the mixture, and stirring at the rotating speed of 80-100rpm for 20-50 minutes per minute to form a wet material;
(3) hydraulic forming: putting the wet material into a tubular mold, and applying 85-115 tons of pressure to press and mold under the action of ultrasonic waves;
(4) drying: baking at 25-35 deg.C for 45-90 min.
Preferably, in the step (2) of the supplementing prescription and the purging prescription, the elm bark powder is added mainly for bonding, and is also plant fiber, flammable and convenient for ignition. Preferably, the addition amount of the elm bark powder is 1-3% of the total mass of the mixture. The elm bark powder has higher viscosity, is used for enhancing the combination compactness among all components, ensures that the finally prepared medicinal moxibustion is firmer and has toughness, is not easy to break and drop dust, can control the combustion speed and prolongs the service life. In addition, the elm bark has the effects of inducing diuresis, treating stranguria and relieving swelling, and can prevent the elm bark from having the effect of relieving swelling after being carelessly burnt by medicinal moxibustion.
The frequency of ultrasonic wave is 65-95KHz for carry out ultrasonic vibration to the wet material in the cast mould, make each component can make the even clearance of filling between the granule of the effective component of each component when the suppression, improve closely knit nature, make the texture more symmetrical, also can make the burning more even in addition, the temperature remains stably, and the drug effect is also more stable.
Preferably, the ultrasonic wave is generated by a clamp type ultrasonic processor fixed on the outer side wall of the tubular mold, the clamp type ultrasonic processor comprises a transducer assembly and a functional clamp, the transducer assembly comprises a transducer and an amplitude transformer, the transducer is connected with the amplitude transformer, and the transducer assembly is connected with the functional clamp. The functional clamp can comprise an irradiation front edge near rod block and an irradiation front edge pipe supporting block, wherein functional clamp cavities for receiving ultrasonic irradiation are arranged in the irradiation front edge near rod block and the irradiation front edge pipe supporting block, and the irradiation front edge near rod block is connected with the pipe type mold for clamping the pipe type mold receiving ultrasonic irradiation; the irradiation front edge near rod block and/or the irradiation front edge pipe supporting block are/is connected with the amplitude transformer through a connecting screw rod.
Compared with the prior art, it has the following beneficial effects: the traditional Chinese medicine is prepared from two prescriptions, namely a purgation prescription and a tonifying prescription, can be flexibly selected according to different symptoms and constitutions, can be used in a dialectical mode, is prepared from 6 selected traditional Chinese medicines, is not added with any toxic additive, is prepared from pure natural components at a proper temperature, maintains the properties of the traditional Chinese medicines, and is safe; after being ignited, the various traditional Chinese medicines take effect synergistically, naturally emit heat, are strong in permeation, free of any stimulation and discomfort, free of anaphylactic reaction, and have the conditioning and health-care effects of clearing away heart-fire, soothing nerves, nourishing yang, moistening lung, nourishing heart, benefiting intelligence, tonifying qi and reinforcing kidney, and the fragrance is pleasant; moderate heat, and has good therapeutic effects of warming muscle, dispelling cold, dispelling pathogenic wind, eliminating dampness, promoting qi and blood circulation, warming and dredging collaterals, promoting blood circulation for removing blood stasis, and relieving pain by permeating into channels and collaterals through transdermal absorption.
Detailed Description
The present invention will be described in detail with reference to specific examples. The embodiment is merely the best case, but the practical use direction of the present invention is not limited thereto.
The invention is based on the words of Huangdi's internal channel, Ling Shu and Jing Mai: preponderance causes purgation, deficiency causes tonification, heat causes excess, cold causes retention, and collapse causes moxibustion. That is, excess yin and yang excess of the body is removed by purgation, insufficiency is compensated when yin and yang are too little, needles are not retained when pathogenic heat is pathogenic heat, needles are retained when cold is pathogenic heat, and qi deficiency such as flaccidity and edema is treated by moxibustion. Combining the theory of Huangdi's inner channel, Ling Shu and Jing Mai, the moxibustion strip of the invention is divided into a tonifying prescription moxibustion strip and a purging prescription moxibustion strip.
Wherein the prescription moxibustion stick comprises Corni fructus, radix rehmanniae Preparata, rhizoma Dioscoreae, radix astragali, radix Codonopsis and 6 major tonics of radix Aconiti lateralis Preparata; radix rehmanniae Preparata is added to the above herbs to nourish yin, tonify kidney, replenish essence and benefit marrow, and is used as monarch drug. Dogwood fruit can nourish liver and kidney and astringe essence; the Chinese yam is used as ministerial drug for tonifying spleen yin and securing essence. The three medicines are matched to nourish the liver, spleen and kidney to form 'three tonics'. In order to strengthen the tonifying effect and strengthen the three major tonics of astragalus, codonopsis pilosula and prepared aconite root, the three tonics are cooperated to take effect to improve the tonifying effect. Has good treatment and improvement effects on various symptoms such as low fever, feverish palms and soles, hectic fever in the afternoon, night sweat, dry mouth and throat, vexation and insomnia, dizziness and tinnitus, red tongue with little coating, thready and rapid pulse and the like, and has lung yin deficiency syndrome, heart yin deficiency syndrome, stomach yin deficiency syndrome, spleen yin deficiency syndrome, liver yin deficiency syndrome, kidney yin deficiency syndrome and the like.
Wherein the XIE prescription moxibustion strip comprises 6 laxative drugs including Poria, cortex moutan, Alismatis rhizoma, rhizoma Pinelliae, Notoginseng radix and Borneolum Syntheticum; wherein Alismatis rhizoma is used as principal drug for promoting diuresis and eliminating turbid pathogen. Cortex moutan is effective for purging ministerial fire; poria cocos, radix Poria cocos, Poria. The three herbs are matched to form the three purgations. In order to strengthen the purgative effect, the three diarrhea-relieving herbs of pinellia tuber, notoginseng and borneol are added, and the three diarrhea-relieving herbs are cooperated to take effect to improve the purgative effect. Has good treatment and improvement effects on various yang deficiency syndromes such as fever, abdominal distension, pain and tenderness, chest distress, dysphoria, even coma and delirium, thick breath, excessive phlegm and saliva, constipation, diarrhea, tenesmus, difficulty in urination, dribbling and painful urination, strong and forceful pulse, pale tongue, thick and greasy tongue fur and the like.
A traditional Chinese medicine for medicinal moxibustion is prepared from the following raw materials in parts by weight:
the preparation method of the medicinal moxibustion traditional Chinese medicine comprises the following steps of:
(1) material preparation and grinding: grinding and crushing the components respectively until the particle size is 90-100 meshes; then uniformly mixing all the components to form a mixture;
(2) mixing and stirring: adding 60-70% ethanol solution into the mixture, wherein the addition amount of the ethanol solution is 45-50% of the total weight of the mixture, and stirring at the rotating speed of 85-95rpm per minute for 35-45 minutes to form a wet material;
(3) hydraulic forming: putting the wet material into a tubular mold, and applying pressure of 90-110 tons under the action of ultrasonic waves for pressing and molding;
(4) drying: baking at 40-45 deg.C for 40-55 min.
The preparation method of the purgative prescription comprises the following steps:
(1) material preparation and grinding: respectively grinding and crushing the tuckahoe, the cortex moutan, the rhizoma alismatis, the pinellia ternate and the panax notoginseng until the particle size is 90-100 meshes, and grinding and crushing the borneol until the particle size is 140-160 meshes; then uniformly mixing all the components to form a mixture;
(2) mixing and stirring: adding 60-70% ethanol solution into the mixture, wherein the addition amount of the ethanol solution is 45-50% of the total weight of the mixture, and stirring at the rotating speed of 85-95rpm per minute for 35-45 minutes to form a wet material;
(3) hydraulic forming: putting the wet material into a tubular mold, and applying pressure of 90-110 tons under the action of ultrasonic waves for pressing and molding;
(4) drying: baking at 25-35 deg.C for 50-70 min.
In the step (2) of the supplementing formula and the purging formula, the elm bark powder is added for mainly performing a bonding function, and is also plant fiber, flammable and convenient to ignite. Preferably, the addition amount of the elm bark powder is 1.5-2.5% of the total mass of the mixture. More preferably, the addition amount of the elm bark powder is 2% of the total mass of the mixture, and the particle size of the elm bark powder is 150-fold 180-mesh sieve. Preferably, the elm bark powder has a particle size of passing through a 160 mesh sieve, thus having an optimum viscosity in combination with each component. The elm bark powder has higher viscosity, is used for enhancing the combination compactness among all components, ensures that the finally prepared medicinal moxibustion is firmer and has toughness, is not easy to break and drop dust, can control the combustion speed and prolongs the service life. In addition, the elm bark powder has the effects of inducing diuresis, treating stranguria and relieving swelling, and can prevent the medicinal moxibustion from having the effect of relieving swelling after being carelessly burnt.
The frequency of the ultrasonic wave is 70-90KHz, and the ultrasonic vibration device is used for carrying out ultrasonic vibration on wet materials in the tubular mold, so that the components can be pressed, the effective components of the components can be uniformly filled in gaps among particles, the compactness is improved, the texture is more uniform, the combustion is more uniform, the temperature is kept stable, and the drug effect is more stable. Preferably, the frequency of the ultrasonic wave is 85 KHz.
Preferably, the ultrasonic wave is generated by a clamp type ultrasonic processor fixed on the outer side wall of the tubular mold, the clamp type ultrasonic processor comprises a transducer assembly and a functional clamp, the transducer assembly comprises a transducer and an amplitude transformer, the transducer is connected with the amplitude transformer, and the transducer assembly is connected with the functional clamp. The functional clamp can comprise an irradiation front edge near rod block and an irradiation front edge pipe supporting block, wherein functional clamp cavities for receiving ultrasonic irradiation are arranged in the irradiation front edge near rod block and the irradiation front edge pipe supporting block, and the irradiation front edge near rod block is connected with the pipe type mold for clamping the pipe type mold receiving ultrasonic irradiation; the irradiation front edge near rod block and/or the irradiation front edge pipe supporting block are/is connected with the amplitude transformer through a connecting screw rod. The tubular mould can be made into various shapes with plum blossom-shaped cross section and the like according to requirements. In order to facilitate ignition and smoke guide, the middle part of the moxibustion stick is provided with a through hole with the inner diameter of 1-5 mm.
This application uses ethanol solution as the stirring solvent, and the addition is about 50% of mixture, can guarantee like this when can the intensive mixing even, ethanol solution also can extract each component active ingredient, and the dispersion, can not increase wet material whole weight too much, and ethanol solution drying volatilizees comparatively fast, and the stoving time is short, practices thrift the energy consumption, improves production efficiency, and can dry under the low temperature condition, can not react and produce the toxic substance, and keeps the property of a medicine of each traditional chinese medicine. And cutting and packaging the finished product, and storing the product at room temperature in a sealed, shady and cool and ventilated state.
Wherein, in the step (3), the press forming pressure range is set according to the following table parameters:
under the above-mentioned pressure condition of press forming of this application, it is that each component is compressed and has appropriate inseparable type, and the surface can not ash and fall the sediment, and have good wilfulness, the firepower is mild when the moxa stick burns, central high-temperature region top temperature is about 600 ℃, peripheral low temperature zone minimum temperature is less than 400 ℃, can not produce the charcoal fire of dryness-heat when burning, this kind of mild fire more is favorable to the health, by the difficult getting angry of moxibustion person, the security of moxa-moxibustion has been increased, the comfort of by the moxibustion person has been improved.
The components herein are ground to a particle size of 85-110 mesh, which facilitates mixing and utilizes ignition and controls the rate of combustion. The borneol is ground and pulverized to be finer, so that the borneol is favorably dispersed among the component particles to better exert the effect.
Toxicology test
First, mouse inhalation toxicity test
1. Materials:
1.1, experimental materials:
the sample was a moxa stick prepared in any of the above examples, and a healthy mouse was placed in a space of 10 cubic meters after ignition.
1.2, animals:
the weight of the healthy mice is 20-28g, and the healthy mice are male and female.
2. The method and the result are as follows:
2.1, test method:
40 NIH white mice with weight of 20-28g and half of each male and female are randomly divided into 4 time period groups by means of horns' method, and the results are shown in the following table.
2.2, results:
the toxic reaction of the mouse is not observed in 1 week after the tested mouse inhales combustion air mixed with the moxibustion strips with relatively high concentration in different periods, which shows that the traditional Chinese medicine for moxibustion is a nontoxic substance. The experimental effects of the other examples are also as described above.
Second, mouse oral acute toxicity test (LD50)
1. Materials:
1.1, experimental materials:
any of the examples samples obtained in the present invention were ground into a powder and blended into food.
1.2, animals:
NIH healthy mice, 20-28g weight, and half male and half female.
2. The method and the result are as follows:
2.1, test method:
40 NIH white mice with the weight of 20-28g and half of each male and female are randomly divided into 4 dosage groups by a horns' method, and the mice are subjected to hollow abdominal intragastric perfusion twice at the gastric perfusion rate of 0.5ml/10g.b.w for 24 hours, the two times are separated by 4 hours, and the results are observed for one week and shown in the following table.
2.2, results:
the tested mice are orally taken with different dosages (LD50 is more than 20.6g/kg. b.w), no toxic reaction of the mice is observed, and the experimental effects of other examples are also as described above; the Chinese medicine for moxibustion is proved to be nontoxic.
The moxibustion application method is that one end of a moxa roll is ignited and is directed at a position to be moxibustion, and the position 2-3 cm away from the skin is subjected to smoking, so that the local part of a patient is warm and does not have burning pain. Generally, moxibustion is performed for 10-15 minutes per acupoint, with the degree of skin areola as the index. Acting on the conception vessel, the kidney channel, the spleen channel and the stomach channel of the abdomen, mainly treating the large acupoints such as Shenque, moisture, Tianshu, Qihai and Guanyuan, has the functions of regulating Chong and ren channels, strengthening the spleen and benefiting the stomach and regulating intestines and fu, and is mainly used for conditioning and treating chest distress, dysphoria, even coma and delirium, thick breath, abundant phlegm and saliva, constipation, tenesmus, dysuria, dribbling and unsmooth pain, forceful pulse, pale tongue, thick and greasy tongue fur, dysmenorrheal, irregular menstruation, pelvic inflammation and other reproductive system diseases, diarrhea, bellyache and other gastrointestinal digestive system diseases.
Clinical data
1.1 general data.
40 subjects who met the inclusion criteria were each from the Guangzhou department of cloud vein medical science and technology, Inc. The subjects were randomly divided into 20 cases each of the drug moxibustion group (treatment group) and moxibustion group (control group). The moxibustion group is divided into yin deficiency and yang deficiency according to actual symptoms, the reinforcing formula moxibustion strip is used for yin deficiency, the purging formula moxibustion strip is used for yang deficiency, and the two groups of patients have no statistical significance (P is more than 0.05) in comparison difference in age and disease course and have comparability.
1.2 inclusion criteria.
(1) The diagnosis standard of primary dysmenorrhea (congealing cold and blood stasis syndrome) is met; (2) the age is more than or equal to 18 years and less than or equal to 35 years; (3) menstrual cycle regularity (28 ± 7) d; (4) signing an informed consent; (5) the VAS score is more than or equal to 3 points; (6) CMSS score > 10.
1.3 exclusion criteria.
(1) The western medicine diagnosis belongs to secondary dysmenorrhea, and the examination proves that the patients with secondary dysmenorrhea are caused by pelvic inflammation, endometriosis, hysteromyoma, ovarian lesion and the like; (2) combined with primary diseases such as cardiovascular and cerebrovascular diseases, liver, kidney and hemopoietic system which seriously endanger life and mental patients, and other diseases which are not suitable for moxibustion; (3) lactating women and pregnant or recently pregnancies; (4) those with allergic constitution, or those known to be allergic to the medicinal component; (5) taking analgesic, sedative and hormone medicine within 1 month before treatment; (6) are participating in other clinical trials.
2. Methods of treatment.
(1) Point selection: the patient takes the supine position and fully exposes the umbilicus and lower abdomen. Shenque acupoint: in the middle of the abdomen, in the center of the umbilicus. Guanyuan acupoint: on the lower abdomen, on the midline of the abdomen, 3 cun below the umbilicus. The acupuncture point location is carried out according to the national standard of the people's republic of China (GB 12346-90).
(2) The moxibustion timing and course of treatment are as follows: moxibustion is applied 5 days before menstruation, and is continuously applied for 7 days in each menstrual cycle and for 3 months in each menstrual cycle.
(3) The operation method comprises the following steps: the medicinal moxibustion group selects the moxibustion strip of the invention to apply moxibustion according to dialectical evidence, and each acupoint is applied for 20 minutes, 1 time/day and 7 times in total. Moxibustion was applied to the control group. The moxibustion is performed by igniting one end of the moxa roll, aiming at the acupoint to be moxibustion, and performing moxibustion at a distance of about 2-3 cm from the skin, so that the local part of the patient is warm and hot without burning pain, and the moxibustion is performed for 20 minutes every acupoint until the skin is reddish and moist.
3, the treatment effect.
3.1 Observation index.
3.1.1 Abdominal pain VAS score.
The pain degree of dysmenorrheal and abdominal pain is evaluated by adopting a Visual Analogue Scale (VAS) which is commonly used internationally, and the change of VAS scores in the treatment group and the control group before and after the treatment and between the groups is compared.
3.1.2 evaluation of the curative effect of the traditional Chinese medicine syndrome.
The changes of the Chinese medicine syndrome score before and after treatment and between the treatment groups and the control group are compared.
The therapeutic effect judgment standard is drawn up according to nimodipine method and clinical research guiding principle of new Chinese medicine.
(1) And (3) healing: the abdominal pain disappears under the menstrual period, and n is more than or equal to 95 percent.
(2) The effect is shown: the abdominal pain during the menstrual period is obviously relieved, and n is more than or equal to 70% and less than 95%.
(3) The method has the following advantages: the abdominal pain is relieved during the menstrual period, and n is more than or equal to 30% and less than 70%.
(4) And (4) invalidation: the abdominal pain under menstrual period is not obviously improved, and n is less than 30 percent.
The curative effect index (n) is (the integral of the traditional Chinese medicine syndrome before treatment-the integral of the traditional Chinese medicine syndrome after 3 months of treatment) or the integral of the traditional Chinese medicine syndrome before treatment multiplied by 100 percent.
3.1.3 adverse reaction observation.
Adverse reactions, which may be associated with therapeutic agents, are well documented.
3.2 statistical methods.
Statistical processing is carried out by using SPSS19.0 statistical software, and the detection result is expressed by mean +/-standard deviation; the significance of the difference between the two groups was tested by t-test. P < 0.05 is a statistically significant sign of the difference. The grade data were analyzed by Ridit.
4 treatment results.
4.1 comparison of pain VAS scores before and after treatment in the two groups, see Table 1.
Table 1 two groups of patients were compared before and after pain VAS scores.
The results in table 1 show that the VAS scores of both groups after treatment were significantly reduced compared to those before treatment, and the treated groups were much lower than the control group, demonstrating a more significant pain relief effect.
4.2 the curative effect of the traditional Chinese medicine syndrome before and after two groups of treatment is judged.
In 20 cases of the treatment group, 3 cases are cured, 13 cases with obvious effect, 4 cases with effect and 1 case with no effect, and the total effective rate is 95 percent; in 20 cases of the control group, 1 case is cured, 6 cases with obvious effect, 8 cases with effect and 4 cases with no effect, and the total effective rate is 80 percent. Ridit analysis showed that the treatment was superior to the control in efficacy, as shown in Table 2.
Table 2 compares the therapeutic effects of the two groups of patients.
| Group of | Cure of disease | Show effect | Is effective | Invalidation | Total effective rate (%) |
| Treatment group | 3 | 13 | 4 | 1 | 95 |
| Control group | 1 | 7 | 8 | 4 | 80 |
The tests show that the externally-applied traditional Chinese medicine moxibustion stick has obvious curative effect on treating primary dysmenorrhea caused by nerve, endocrine and immune network imbalance and partial microcirculation disturbance of uterus, and the curative effect is superior to that of a pure moxibustion treatment control group. And (4) conclusion: the externally applied traditional Chinese medicine moxibustion stick has a better treatment effect in clinical treatment of primary dysmenorrhea. No adverse reaction appeared during observation.
In addition, clinical application proves that the invention has good curative effect on other symptoms. In general, based on the theory of traditional Chinese medicine channels and collaterals, the Chinese herbal medicines with strong infiltration capacity are collected, the heat of the palm of a user and the inherent original qi are used as driving forces, and three curative effects of medicine, heat treatment and acupoint stimulation are exerted on an affected part. Avoids the bitter skin and flesh of acupuncture and moxibustion, has quicker and stronger effect taking speed, and has quicker and more thorough effects of promoting blood circulation, removing blood stasis and relieving pain.
The above description is only a preferred embodiment of the present invention, and the scope of the present invention should not be limited thereby, and all the simple equivalent changes and modifications made in the claims and the description of the present invention are within the scope of the present invention.
Claims (5)
1. A traditional Chinese medicine for moxibustion is characterized in that: the prescription consists of a tonifying prescription and a purgative prescription, wherein the tonifying prescription is prepared from the following components in parts by weight: 5-10 parts of dogwood, 5-10 parts of prepared rehmannia root, 5-10 parts of Chinese yam, 5-10 parts of astragalus membranaceus, 5-10 parts of codonopsis pilosula and 5-10 parts of prepared monkshood;
the purgative prescription is prepared from the following components in parts by weight: 5-10 parts of poria cocos, 5-10 parts of cortex moutan, 5-10 parts of rhizoma alismatis, 5-10 parts of pinellia ternate, 2.5-5 parts of pseudo-ginseng and 2.5-5 parts of borneol.
2. The traditional Chinese medicine for medicinal moxibustion according to claim 1, which is characterized in that the tonifying prescription is prepared from the following components in parts by weight: 6-8 parts of dogwood, 6-8 parts of prepared rehmannia root, 6-8 parts of Chinese yam, 6-8 parts of astragalus, 6-8 parts of codonopsis pilosula and 6-8 parts of prepared monkshood;
the purgative formula is prepared from the following components in parts by weight: 6-8 parts of poria cocos, 6-8 parts of cortex moutan, 6-8 parts of rhizoma alismatis, 6-8 parts of pinellia ternate, 3-4 parts of pseudo-ginseng and 3-4 parts of borneol.
3. The method for preparing a medicinal moxibustion traditional Chinese medicine according to claim 1 or 2, characterized in that the tonifying prescription and the purging prescription are respectively made into moxibustion sticks, wherein the preparation method of the tonifying prescription comprises the following steps:
(1) material preparation and grinding: grinding and crushing the components respectively until the particle size is 85-110 meshes; then uniformly mixing all the components to form a mixture;
(2) mixing and stirring: adding 50-75% ethanol solution into the mixture, wherein the addition amount of the ethanol solution is 40-55% of the total weight of the mixture, and stirring at the rotating speed of 80-100rpm for 20-50 minutes per minute to form a wet material;
(3) hydraulic forming: putting the wet material into a tubular mold, and applying 85-115 tons of pressure to press and mold under the action of ultrasonic waves;
(4) drying: baking at 40-45 deg.C for 30-60 min;
the preparation method of the purgative prescription comprises the following steps:
(1) material preparation and grinding: respectively grinding and crushing the tuckahoe, the cortex moutan, the rhizoma alismatis, the pinellia ternate and the panax notoginseng until the particle size is 85-110 meshes, and grinding and crushing the borneol until the particle size is 120-180 meshes; then uniformly mixing all the components to form a mixture;
(2) mixing and stirring: adding 50-75% ethanol solution into the mixture, wherein the addition amount of the ethanol solution is 40-55% of the total weight of the mixture, and stirring at the rotating speed of 80-100rpm for 20-50 minutes per minute to form a wet material;
(3) hydraulic forming: putting the wet material into a tubular mold, and applying 85-115 tons of pressure to press and mold under the action of ultrasonic waves;
(4) drying: baking at 25-35 deg.C for 45-90 min.
4. The method for preparing a medicinal moxibustion traditional Chinese medicine according to claim 1 or 2, characterized in that in the step (2) of the tonifying prescription and the purging prescription, elm bark powder is added; the addition amount of the elm bark powder is 1-3% of the total mass of the mixture.
5. The method for preparing a medicinal moxibustion traditional Chinese medicine according to claim 3, characterized in that the frequency of the ultrasonic wave is 65-95 KHz.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011285476.6A CN112220876A (en) | 2020-11-17 | 2020-11-17 | Medicinal moxibustion traditional Chinese medicine and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011285476.6A CN112220876A (en) | 2020-11-17 | 2020-11-17 | Medicinal moxibustion traditional Chinese medicine and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112220876A true CN112220876A (en) | 2021-01-15 |
Family
ID=74123470
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011285476.6A Pending CN112220876A (en) | 2020-11-17 | 2020-11-17 | Medicinal moxibustion traditional Chinese medicine and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112220876A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773907A (en) * | 2010-02-05 | 2010-07-14 | 严锦璇 | Forceps-shaped ultrasonic processor and application thereof |
| CN105619867A (en) * | 2016-01-06 | 2016-06-01 | 中国工程物理研究院化工材料研究所 | Method for performing pressing formation on powder material under assistance of ultrasonic vibration |
| CN108969740A (en) * | 2018-08-30 | 2018-12-11 | 刘春兰 | A kind of thunder gunpowder moxibustion item and preparation method thereof |
-
2020
- 2020-11-17 CN CN202011285476.6A patent/CN112220876A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101773907A (en) * | 2010-02-05 | 2010-07-14 | 严锦璇 | Forceps-shaped ultrasonic processor and application thereof |
| CN105619867A (en) * | 2016-01-06 | 2016-06-01 | 中国工程物理研究院化工材料研究所 | Method for performing pressing formation on powder material under assistance of ultrasonic vibration |
| CN108969740A (en) * | 2018-08-30 | 2018-12-11 | 刘春兰 | A kind of thunder gunpowder moxibustion item and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 王海萍: "灸法补泻刍议" * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101810685B (en) | Chinese medicinal composition for treating gonitis and preparation method thereof | |
| CN114306563B (en) | Gynecological climacteric menstruation moxibustion and preparation method thereof | |
| CN103316146A (en) | Traditional Chinese medicinal preparation for anesthesia | |
| CN103041023A (en) | Traditional Chinese medicine composition for treating kidney deficiency infertility of women | |
| CN102631655B (en) | Medicine for treating coronary heart disease and preparation method for medicine | |
| CN104998168A (en) | Blood-enriching and qi-tonifying compound traditional Chinese lozenge and preparation technology thereof | |
| CN116942780B (en) | Traditional Chinese medicine compound for relieving chronic obstructive emphysema and feikang hot compress patch | |
| CN101455795B (en) | Traditional Chinese medicine preparation for treating spontaneous perspiration and preparation method thereof | |
| CN214511887U (en) | Multifunctional thumb-tack needle | |
| CN105031331A (en) | Navel patch for treating dysmenorrhoea and preparation method thereof | |
| CN112220876A (en) | Medicinal moxibustion traditional Chinese medicine and preparation method thereof | |
| CN108434362A (en) | A kind of Chinese mugwort cake | |
| CN114533831A (en) | Traditional Chinese medicine composition with effects of warming spleen and stomach for dispelling cold and eliminating dampness, and promoting blood circulation for removing obstruction in channels to relieve pain and fomenting bag thereof | |
| CN113876867A (en) | Agilawood moxa stick for treating irregular menstruation and preparation method thereof | |
| CN102579607B (en) | Chinese medicine composition for treating acne | |
| CN111265609A (en) | Traditional Chinese medicine composition for adjuvant treatment of true myopia and preparation method thereof | |
| CN104547553A (en) | Traditional Chinese medicine for treating nervous endocrine disorder | |
| CN114146134B (en) | Traditional Chinese medicine composition with effects of warming channels and relieving pain and application thereof | |
| CN1060073C (en) | Externally used medicine bag for curing chronic pelvic infection, endometriosis, chronic cervicitis and menalgia and its making process | |
| CN112263471A (en) | Multifunctional thumb-tack needle | |
| CN103393927B (en) | Medicine for treating climacteric syndrome and preparation method thereof | |
| CN114732882B (en) | Traditional Chinese medicine composition and preparation method and application thereof | |
| CN108310269A (en) | A kind of Chinese mugwort cake | |
| CN106389991A (en) | Navel treatment drug composition for andrology diseases as well as preparation method and application of navel treatment drug composition | |
| CN112353684A (en) | Multifunctional cowherb seed medicinal moxibustion patch |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |