CN112043802A - Preparation for treating vaginitis - Google Patents
Preparation for treating vaginitis Download PDFInfo
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- CN112043802A CN112043802A CN202011157353.4A CN202011157353A CN112043802A CN 112043802 A CN112043802 A CN 112043802A CN 202011157353 A CN202011157353 A CN 202011157353A CN 112043802 A CN112043802 A CN 112043802A
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Abstract
The invention relates to the field of traditional Chinese medicines, in particular to a preparation for treating vaginitis, which is prepared from the following traditional Chinese medicinal materials in parts by weight: 3.0-12.0 parts of radix stemonae, 3.0-12.0 parts of cynanchum atratum, 3.0-12.0 parts of rhizoma alismatis, 2.0-10.0 parts of bighead atractylodes rhizome, 2.0-10.0 parts of radix sophorae flavescentis, 2.0-10.0 parts of radix astragali preparata, 2.0-10.0 parts of rhizoma bambusae, 2.0-15.0 parts of clinopodium herb, 2.0-10.0 parts of anemone rubrum, 2.0-15.0 parts of cherry leaf, 3.0-9.0 parts of hairyvein agrimony and 3.0-9.0 parts of herba hyperici japonici. The invention selects a medicine formula, and the medicine components are matched according to the syndrome differentiation and are mutually assisted in action, so that the effects of eliminating inflammation, repairing lesion focus, enhancing immunity and building the body are achieved together. The components of the composition are all natural traditional Chinese medicinal materials, and the composition is simple and convenient to prepare, wide in medicinal source and low in cost. Clinical application proves that the preparation has mild medicine property, no obvious toxic or side effect, and higher treatment effective rate and cure rate.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a preparation for treating vaginitis.
Background
Gynecological vaginitis is inflammation of vaginal mucosa and connective tissue under the mucosa, and is a common disease in gynecological outpatient service. Normal healthy women have a natural defense function against pathogen invasion due to anatomical and biochemical characteristics, when the natural defense function of the vagina is destroyed, the pathogen is easy to invade to cause vagina inflammation, young women and postmenopausal women have low vagina resistance due to lack of estrogen, thin vagina epithelium, reduced intracellular glycogen content and high vagina pH value of about 7, and are easy to infect compared with adolescent and reproductive women.
Vaginitis is a disease caused by the change of the pH value of the vagina, weakened resistance and the invasion of pathogenic bacteria. The common symptoms are increased vaginal secretion, pruritus vulvae, burning pain, frequent micturition, painful urination and dyspareunia. Vaginitis is a common disease and frequently encountered disease, if the vaginitis is not timely treated, the vaginitis is converted into chronic inflammation and is long-lasting and sterile, not only is the health, life and work of a body seriously affected, but also pathogens can infect a fetus through placenta to cause abortion, premature birth, congenital developmental deformity and mental retardation, and pelvic inflammation, peritonitis, septicemia and life crisis can be caused.
Western medicine mainly adopts pain-relieving and inflammation-diminishing antibiotics to treat vaginitis, and the medicines have toxic and side effects and adverse reactions of different degrees. At present, the medicines for treating gynecological inflammation are mainly divided into western medicines, traditional Chinese medicines and combination of the western medicines and the traditional Chinese medicines. However, the treatment of the medicines has the defects of poor curative effect, long treatment course, incapability of completely eradicating, easy relapse after treatment and the like.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides a preparation for treating vaginitis, which has the advantages of good curative effect, short treatment course, difficult relapse, convenient use and low cost, and solves the problems mentioned in the background technology.
(II) technical scheme
In order to achieve the purpose, the invention is realized by the following technical scheme:
a preparation for treating vaginitis is prepared from the following Chinese medicinal materials in parts by weight: 3.0-12.0 parts of radix stemonae, 3.0-12.0 parts of cynanchum atratum, 3.0-12.0 parts of rhizoma alismatis, 2.0-10.0 parts of bighead atractylodes rhizome, 2.0-10.0 parts of radix sophorae flavescentis, 2.0-10.0 parts of radix astragali preparata, 2.0-10.0 parts of rhizoma bambusae, 2.0-15.0 parts of clinopodium herb, 2.0-10.0 parts of anemone rubrum, 2.0-15.0 parts of cherry leaf, 3.0-9.0 parts of hairyvein agrimony and 3.0-9.0 parts of herba hyperici japonici.
The preferable preparation for treating vaginitis is a decoction prepared from the following Chinese medicinal materials in parts by weight: 5.0 to 10.0 parts of stemona root, 5.0 to 10.0 parts of cynanchum atratum, 5.0 to 10.0 parts of rhizoma alismatis, 5.0 to 8.0 parts of bighead atractylodes rhizome, 5.0 to 8.0 parts of sophora flavescens, 4.0 to 8.0 parts of radix astragali preparata, 5.0 to 8.0 parts of rhizopus bambusicola, 5.0 to 10.0 parts of clinopodium herb, 5.0 to 8.0 parts of anemone chinensis, 5.0 to 10.0 parts of cherry leaf, 4.0 to 8.0 parts of hairyvein agrimony and 4.0 to 8.0 parts of hypericum japonicum.
The preferable preparation for treating vaginitis is a decoction prepared from the following Chinese medicinal materials in parts by weight: 7.0 parts of stemona root, 8.0 parts of cynanchum atratum, 6.0 parts of rhizoma alismatis, 7.0 parts of bighead atractylodes rhizome, 6.0 parts of radix sophorae flavescentis, 7.0 parts of radix astragali preparata, 6.5 parts of rhizoma bambusae, 7.5 parts of herba clinopodii, 7.0 parts of gynura bicolor, 8.0 parts of cherry leaf, 6.5 parts of hairyvein agrimony and 6.5 parts of herba hyperici japonici.
The preferable preparation for treating vaginitis is a decoction prepared from the following Chinese medicinal materials in parts by weight: 9.0 parts of stemona root, 7.0 parts of cynanchum atratum, 7.5 parts of rhizoma alismatis, 6.5 parts of bighead atractylodes rhizome, 7.0 parts of radix sophorae flavescentis, 6.0 parts of radix astragali preparata, 7.5 parts of rhizoma bambusae, 8.5 parts of herba clinopodii, 6.0 parts of gynura bicolor, 7.0 parts of cherry leaf, 7.0 parts of hairyvein agrimony and 5.5 parts of herba hyperici japonici.
The medicinal properties of the raw materials are as follows:
stemona root, sweet, bitter and slightly cold in taste; enters lung meridian and has the effects of moistening lung, descending qi, relieving cough, killing parasites and killing lice; can be used for treating chronic cough, pulmonary tuberculosis cough, and pertussis; it is used for treating head louse, body louse, enterobiasis, and pudendal pruritus; honey radix Stemonae has effects of moistening lung and relieving cough; can be used for treating cough due to yin deficiency. In vitro antibacterial test for pathogenic microorganism resisting effect shows that the radix Stemonae ethanol extract has antibacterial effect on Staphylococcus aureus, Staphylococcus albus, beta hemolytic streptococcus, Bacillus anthracis, Bacillus pneumoniae, Bacillus dysenteriae, Bacillus proteus, plague bacillus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, Salmonella paratyphi and human type Bacillus tuberculosis. The radix Stemonae water extract (1: 3) has effect in inhibiting various dermatophytes, and can inhibit growth of Trichophyton sinense at 20% concentration, Trichophyton schoenleinii, Microsporum Okawayanum and Microsporum lanuginosum at 40% concentration.
Cynanchum atratum is bitter, salty and slightly cold in taste, enters stomach, liver and kidney channels, and has the effects of clearing heat and cooling blood, inducing diuresis and treating stranguria, and detoxifying and treating sore; can be used for treating fever due to pathogenic heat, yin deficiency, bone steaming, fatigue, puerperal fever due to blood deficiency, heat stranguria, blood stranguria, carbuncle, cellulitis, and toxic swelling. The main chemical components of cynanchum atratum comprise steroidal glycosides, alkaloids, aromatics, volatile oil, fatty acids and others; the pharmaceutical components of cynanchum atratum are mainly steroidal glycosides, and the pharmacological actions mainly include antibiosis, antiphlogosis, immunosuppression and the like.
Alisma orientale, sweet and light in taste and cold in nature; entering kidney and bladder meridians; has effects in promoting diuresis, eliminating dampness, clearing away heat, eliminating turbid pathogen, and reducing blood lipid; can be used for treating dysuria, edema, abdominal distention, diarrhea, oliguria, phlegm retention, vertigo, pyretic stranguria, pain, and hyperlipidemia. Alismatis rhizoma contains various tetracyclic triterpene ketol derivatives, choline, lecithin, sesquiterpene, calcium, magnesium, and potassium; and contains flavone, organic acid, amino acid, polysaccharide, volatile oil, fatty acid, resin, protein, starch, etc. Rhizoma Alismatis has effects of reducing blood viscosity, promoting urination, relieving spasm, protecting liver, resisting inflammation, and regulating immunity.
White atractylodes rhizome, bitter, sweet and warm; spleen and stomach meridians entered; has the effects of invigorating spleen, invigorating qi, eliminating dampness, and promoting diuresis; mainly has effects of tranquilizing, vasodilating, resisting blood coagulation, resisting gastric ulcer, protecting liver, promoting bile flow, promoting urination, strengthening body, enhancing immunity, resisting oxidation, resisting bacteria, etc.; bai Zhu is used for strengthening spleen, drying dampness and inducing diuresis. Atractylodis rhizoma has effects in regulating gastrointestinal motility, relieving inflammation, and promoting urination; rhizoma Atractylodis Macrocephalae has remarkable and persistent diuretic effects, and its effective component is beta-eucalyptol, which can strongly inhibit (Na)+ -,K+ -) Phosphorylation by ATPase (i.e., Na. E1 Na. E1P).
Kuh-seng, bitter in taste and cold in nature; the channels of heart, liver, stomach, large intestine and bladder; has effects in clearing away heat, eliminating dampness, killing parasite, and promoting urination; it can be used for treating dysentery due to damp-heat pathogen, hematochezia, jaundice, dysuresia, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, and pyocutaneous disease due to damp toxin. The matrine has obvious inhibition effect on dysentery bacillus, colon bacillus, proteus, beta hemolytic streptococcus and staphylococcus aureus; the radix Sophorae Flavescentis and total matrines have inhibitory effect on cytopathic effect caused by Coxsackie B3 group virus. Matrine has significant anti-inflammatory and antipyretic effects.
Radix astragali Preparata, sweet and warm; entering lung and spleen meridians; invigorating qi, consolidating superficial resistance, promoting urination, removing toxic substances, expelling pus, healing sore, and promoting granulation; can be used for treating deficiency of qi, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, exterior deficiency, spontaneous perspiration, qi deficiency, edema, carbuncle, cellulitis, intractable ulcer, blood deficiency, sallow complexion, internal heat, and diabetes.
Zhugen Qin, sweet and slightly bitter in flavor, cold in nature; nourishing yin, purging fire, promoting blood circulation, and regulating menstruation; it is used to treat cough due to overstrain and heat, rheumatic arthralgia, menoxenia, and traumatic injury. The rhizoma Bambusae seven contains stearic acid, palmitic acid, betulin, Na, Mg, K, Cu, Zn, Ca and other elements, and also contains volatile oil, total saponin, total polyphenol and total polysaccharide, wherein the total polyphenol has strong antibacterial activity.
Herba Pteridis Dactylinae, bitter and sweet in taste, and cool in nature; entering liver meridian; has the effects of clearing away heat and toxic materials, and promoting diuresis; external use for diminishing inflammation and relieving swelling; the herba Scisseria has tranquilizing, antiinflammatory, antibacterial, and antipyretic effects.
The gynura bicolor is sweet in taste and cool in nature; entering lung and liver meridians; has effects in clearing away heat, cooling blood, relieving cough, eliminating phlegm, removing toxic materials, and relieving swelling; the semiaquilegia root contains iron elements with hematopoiesis function, flavonoid compounds, provitamin A and an enzyme agent manganese element, thereby having the effects of promoting blood circulation, stopping bleeding, detoxifying and reducing swelling. The components of flavonoids, zinc, manganese, vitamin E and the like contained in the semiaquilegia root can enhance the immunity of a human body, and the elements of iron, copper and the like have good effects on treating various blood diseases. The semiaquilegia root not only can enhance the oxidation resistance of the organism and remove free radicals, but also has the pharmacological functions of antibiosis, anti-inflammation, blood sugar and blood fat regulation and anticoagulation.
Cherry leaf, sweet in flavor and mild in nature; spleen and liver meridian entered; has the effects of warming the middle-jiao and strengthening the spleen, relieving cough and stopping bleeding, detoxifying and killing insects; it can be used for treating stomach cold, dyspepsia, diarrhea, cough, hematemesis, carbuncle, ulcer, carbuncle, snake and insect bite, and trichomonas vaginalis.
Agrimony is bitter, astringent and flat; heart and liver meridian entered; has effects in stopping bleeding, stopping malaria, relieving dysentery, removing toxic materials, and tonifying deficiency; has effects in tonifying heart, increasing blood pressure, promoting blood coagulation, stopping bleeding, cooling blood, and inhibiting bacteria; the herba et Gemma Agrimoniae contains chemical components such as phenol, ester, flavone, glucoside, organic acid, volatile oil, etc.; has analgesic, antiinflammatory, antibacterial, antiinflammatory, antiviral, and immunity enhancing effects; the organic acid and phenol components contained in herba et Gemma Agrimoniae have effect in inactivating and removing Trichomonas vaginalis.
Herba Hyperici Japonici, pungent and cool in nature; entering liver meridian; has the effects of clearing liver and stopping endogenous wind.
(III) advantageous effects
The invention provides a preparation for treating vaginitis, which has the following beneficial effects:
(1) the preparation of the invention is mainly prepared into decoction by stemona root, cynanchum atratum, rhizoma alismatis, bighead atractylodes rhizome, sophora flavescens, radix astragali preparata, rhizoma notoginseng, clinopodium polycephalum, gynura bicolor, cherry leaf, hairyvein agrimony and hypericum japonicum. Wherein, radix Stemonae has effects of invigorating spleen and kidney, replenishing blood and qi, relieving swelling and pain, and astringing for hemostasis; radix Cynanchi Atrati has effects of clearing away heat and toxic materials, relieving swelling and leukorrhagia; rhizoma Alismatis has effect in clearing away heat; radix Sophorae Flavescentis has effects of clearing heat, eliminating dampness, dispelling pathogenic wind, killing parasite, stopping bleeding, and removing toxic substance; rhizoma Bambusae is effective in nourishing yin and lowering fire; the herba Scissiae has effects of dispelling pathogenic wind and clearing heat; herba Hyperici Japonici has effects of clearing liver-fire, calming endogenous wind, suppressing hyperactive liver, and clearing pathogenic fire; the rhizoma atractylodis macrocephalae has the effects of strengthening spleen and replenishing qi; the folium Pruni Pseudocerasi has effects of promoting diuresis, treating stranguria, killing parasite, relieving itching, dispelling cold, replenishing fire, warming spleen and stomach, and invigorating spleen.
(2) The invention selects a medicine formula, and the medicine components are matched according to the syndrome differentiation and are mutually assisted in action, so that the effects of eliminating inflammation, repairing lesion focus, enhancing immunity and building the body are achieved together.
(3) The components of the composition are all natural traditional Chinese medicinal materials, and the composition is simple and convenient to prepare, wide in medicinal source and low in cost. Clinical application proves that the preparation has mild medicine property, no obvious toxic or side effect, and higher treatment effective rate and cure rate.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example 1
A preparation for treating vaginitis is prepared from the following Chinese medicinal materials in parts by weight: 9.0 g of stemona root, 7.0 g of cynanchum atratum, 7.5 g of alisma orientale, 6.5 g of atractylodes macrocephala, 7.0 g of sophora flavescens, 6.0 g of astragalus membranaceus preparata, 7.5 g of rhizomadryvine root, 8.5 g of clinopodium polycephalum, 6.0 g of gynura bicolor, 7.0 g of cherry leaf, 7.0 g of agrimony and 5.5 g of hypericum japonicum.
The preparation method of the preparation for treating vaginitis comprises the following steps:
(1) weighing the above radix Stemonae, radix Cynanchi Atrati, Alismatis rhizoma, Atractylodis rhizoma, radix Sophorae Flavescentis, radix astragali Preparata, rhizoma Panacis japonici, herba Scisseria chinensis, herba Begoniae Laciniatae, folium Pruni Pseudocerasi, herba et Gemma Agrimoniae and herba Gei Piloselloidis respectively;
(2) putting all the Chinese medicinal materials weighed by the fool book into a decocting tool, and adding clean water meeting the standard of drinking water for life, wherein the water adding amount is 4-5 cm higher than the surface of the Chinese medicinal materials; soaking for 45 minutes before decocting to fully moisten the decoction so as to facilitate the full decoction; boiling with strong fire, decocting with slow fire for half an hour, removing residue, and collecting decoction.
Example 2
A preparation for treating vaginitis is prepared from the following Chinese medicinal materials in parts by weight: 7.0 g of stemona root, 8.0 g of cynanchum atratum, 6.0 g of alisma orientale, 7.0 g of atractylodes macrocephala, 6.0 g of sophora flavescens, 7.0 g of astragalus membranaceus preparata, 6.5 g of rhizomadryvine root, 7.5 g of clinopodium polycephalum, 7.0 g of gynura bicolor, 8.0 g of cherry leaf, 6.5 g of agrimony and 6.5 g of herba hyperici japonici.
The preparation method of the preparation for treating vaginitis comprises the following steps:
(1) weighing the above radix Stemonae, radix Cynanchi Atrati, Alismatis rhizoma, Atractylodis rhizoma, radix Sophorae Flavescentis, radix astragali Preparata, rhizoma Panacis japonici, herba Scisseria chinensis, herba Begoniae Laciniatae, folium Pruni Pseudocerasi, herba et Gemma Agrimoniae and herba Gei Piloselloidis respectively;
(2) putting all the Chinese medicinal materials weighed by the fool book into a decocting tool, and adding clean water meeting the standard of drinking water for life, wherein the water adding amount is 4-5 cm higher than the surface of the Chinese medicinal materials; soaking for 45 minutes before decocting to fully moisten the decoction so as to facilitate the full decoction; boiling with strong fire, decocting with slow fire for half an hour, removing residue, and collecting decoction.
Example 3
A preparation for treating vaginitis, 11.0 g of radix stemonae, 6.0 g of cynanchum atratum, 11.0 g of rhizoma alismatis, 4.0 g of bighead atractylodes rhizome, 9.0 g of radix sophorae flavescentis, 5.0 g of radix astragali preparata, 4.0 g of rhizoma bambusae, 10.0 g of herba clinopodii, 10.0 g of gynura bicolor, 5.0 g of cherry leaf, 9.0 g of hairyvein agrimony and 5.0 g of herba hyperici japonici.
The preparation method of the preparation for treating vaginitis comprises the following steps:
(1) weighing the above radix Stemonae, radix Cynanchi Atrati, Alismatis rhizoma, Atractylodis rhizoma, radix Sophorae Flavescentis, radix astragali Preparata, rhizoma Panacis japonici, herba Scisseria chinensis, herba Begoniae Laciniatae, folium Pruni Pseudocerasi, herba et Gemma Agrimoniae and herba Gei Piloselloidis respectively;
(2) putting all the Chinese medicinal materials weighed by the fool book into a decocting tool, and adding clean water meeting the standard of drinking water for life, wherein the water adding amount is 4-5 cm higher than the surface of the Chinese medicinal materials; soaking for 45 minutes before decocting to fully moisten the decoction so as to facilitate the full decoction; boiling with strong fire, decocting with slow fire for half an hour, removing residue, and collecting decoction.
Example 4
A preparation for treating vaginitis, 10.0 g of radix stemonae, 9.5 g of cynanchum atratum, 9.0 g of rhizoma alismatis, 5.0 g of bighead atractylodes rhizome, 8.0 g of radix sophorae flavescentis, 8.0 g of radix astragali preparata, 6.0 g of rhizoma bambusae, 8.0 g of herba clinopodii, 8.0 g of gynura bicolor, 7.0 g of cherry leaf, 8.0 g of hairyvein agrimony and 7.0 g of herba hyperici japonici.
The preparation method of the preparation for treating vaginitis comprises the following steps:
(1) weighing the above radix Stemonae, radix Cynanchi Atrati, Alismatis rhizoma, Atractylodis rhizoma, radix Sophorae Flavescentis, radix astragali Preparata, rhizoma Panacis japonici, herba Scisseria chinensis, herba Begoniae Laciniatae, folium Pruni Pseudocerasi, herba et Gemma Agrimoniae and herba Gei Piloselloidis respectively;
(2) putting all the Chinese medicinal materials weighed by the fool book into a decocting tool, and adding clean water meeting the standard of drinking water for life, wherein the water adding amount is 4-5 cm higher than the surface of the Chinese medicinal materials; soaking for 45 minutes before decocting to fully moisten the decoction so as to facilitate the full decoction; boiling with strong fire, decocting with slow fire for half an hour, removing residue, and collecting decoction.
Example 5
A preparation for treating vaginitis, 6.0 g of radix stemonae, 11.5 g of cynanchum atratum, 5.0 g of rhizoma alismatis, 9.0 g of bighead atractylodes rhizome, 5.0 g of radix sophorae flavescentis, 9.0 g of radix astragali preparata, 9.0 g of rhizoma bambusae, 6.0 g of herba clinopodii, 5.0 g of gynura bicolor, 10.0 g of cherry leaf, 5.0 g of hairyvein agrimony and 9.0 g of herba hyperici japonici.
The preparation method of the preparation for treating vaginitis comprises the following steps:
(1) weighing the above radix Stemonae, radix Cynanchi Atrati, Alismatis rhizoma, Atractylodis rhizoma, radix Sophorae Flavescentis, radix astragali Preparata, rhizoma Panacis japonici, herba Scisseria chinensis, herba Begoniae Laciniatae, folium Pruni Pseudocerasi, herba et Gemma Agrimoniae and herba Gei Piloselloidis respectively;
(2) putting all the Chinese medicinal materials weighed by the fool book into a decocting tool, and adding clean water meeting the standard of drinking water for life, wherein the water adding amount is 4-5 cm higher than the surface of the Chinese medicinal materials; soaking for 45 minutes before decocting to fully moisten the decoction so as to facilitate the full decoction; boiling with strong fire, decocting with slow fire for half an hour, removing residue, and collecting decoction.
The processing technology of the radix astragali Preparata in the above embodiments is as follows:
(1) refining Mel, placing Mel in a pan, heating to boil slowly, maintaining slight boiling with slow fire, removing foam and wax floating on the surface, and filtering to remove impurities such as dead bee with gauze or gauze; the thick honey can be diluted by adding boiled water, filtered and refined continuously. Generally, the tortoise is soaked in the water, the stickiness of the hand test is slightly stronger than that of the cow honey, the color is slightly deepened, the temperature is 105t, and the specific gravity is 1.30;
(2) taking refined honey, diluting with a proper amount of boiled water, spraying into the raw astragalus slices, uniformly stirring, and moistening for 4-6 hours (so that the honey is completely absorbed);
(3) putting the astragalus slices into a frying pan, frying with slow fire, turning over frequently during frying, and frying until the astragalus slices are dark yellow and uniform, have slight focal spots and are glossy; the decoction pieces are not sticky, and the hand feeling is changed from heavy stagnation to light when the decoction pieces are fried; the decoction pieces are stirred by hand with slight sandy noise after being taken out of the pot and cooled. The agglomeration is loose, the powder can be scattered by gentle rubbing, and the pieces of decoction are not adhered;
(4) taking out and cooling. 25kg of refined honey is used for every 100 astragalus roots.
Clinical effect verification test
1. Clinical data
The general data were from 160 out-patient cases aged 26 to 55 years, with an average age of 41.8 years. All patients were randomized, evenly divided into 3 treatment groups and one control group, 40 per group. The 4 groups have no significant difference in age, disease course, disease condition and the like (P >0.05) and are comparable.
2. Diagnostic criteria
Leucorrhea is increased, or yellow or smelly, pudendum pruritus, trichomonas or mold is found by smear microscopy of vaginal secretion, and 150 patients are all patients with vaginitis with the symptoms.
3. Criteria for efficacy assessment
And (3) curing: the leucorrhea and the color are normal, the pudendum is not itchy, and the vaginal secretion smear microscopic examination does not generate trichomonas or mould.
The method has the following advantages: the leucorrhea and color are normal, the pudendum is not itchy, and smear microscopy of vaginal secretion finds 1-2 trichomonas or mould.
And (4) invalidation: there was no improvement in clinical signs and no change compared to pre-treatment.
4. Method of treatment
The raw materials are cleaned, decocted, fumigated and washed for external use, one dose is taken every day, each dose is divided into morning and evening 2 times, each time is 20 minutes, 10 days are a treatment course, and two treatment courses are used continuously. Wherein, the treatment group 1 is treated by the traditional Chinese medicine external lotion of the embodiment 1 of the invention; the treatment group 2 is treated by the traditional Chinese medicine external lotion of the embodiment 2 of the invention; the treatment group 3 was treated with the traditional Chinese medicine external lotion of example 3 of the present invention.
The control group is treated by taking western medicines, namely fluconazole is orally taken 2-3 times a day, 1-2 granules are taken each time, 10 days are 1 treatment course, and two treatment courses are used continuously.
5. Therapeutic results
Treatment group 1: 26 cases are cured clinically, accounting for 65.0 percent; 12 effective cases account for 30.0 percent; invalid 2 cases; the total effective rate is 95.0%.
Treatment group 2: 24 cases are cured clinically, accounting for 60.0 percent; 12 effective cases account for 30.0 percent; invalid 4 cases; the total effective rate is 90.0%.
Treatment group 3: 20 cases are cured clinically, accounting for 50.0 percent; 14 cases are effective, accounting for 35 percent; 6 cases of invalidation; the total effective rate is 85%.
Control group: 17 cases are cured clinically, accounting for 42.5%; the effective 10 cases account for 25.0 percent; invalid 13 cases; the total effective rate is 67.5%.
The treatment results show that the cure rate and the total effective rate of the treatment group are obviously better than those of the control group, and the treatment group has comparability (P < 0.05).
The preparation of the invention is mainly prepared into decoction by stemona root, cynanchum atratum, rhizoma alismatis, bighead atractylodes rhizome, sophora flavescens, radix astragali preparata, rhizoma notoginseng, clinopodium polycephalum, gynura bicolor, cherry leaf, hairyvein agrimony and hypericum japonicum. Wherein, radix Stemonae has effects of invigorating spleen and kidney, replenishing blood and qi, relieving swelling and pain, and astringing for hemostasis; radix Cynanchi Atrati has effects of clearing away heat and toxic materials, relieving swelling and leukorrhagia; rhizoma Alismatis has effect in clearing away heat; radix Sophorae Flavescentis has effects of clearing heat, eliminating dampness, dispelling pathogenic wind, killing parasite, stopping bleeding, and removing toxic substance; rhizoma Bambusae is effective in nourishing yin and lowering fire; the herba Scissiae has effects of dispelling pathogenic wind and clearing heat; herba Hyperici Japonici has effects of clearing liver-fire, calming endogenous wind, suppressing hyperactive liver, and clearing pathogenic fire; the rhizoma atractylodis macrocephalae has the effects of strengthening spleen and replenishing qi; the folium Pruni Pseudocerasi has effects of promoting diuresis, treating stranguria, killing parasite, relieving itching, dispelling cold, replenishing fire, warming spleen and stomach, and invigorating spleen.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (4)
1. A preparation for treating vaginitis is characterized by being prepared from the following Chinese medicinal materials in parts by weight: 3.0-12.0 parts of radix stemonae, 3.0-12.0 parts of cynanchum atratum, 3.0-12.0 parts of rhizoma alismatis, 2.0-10.0 parts of bighead atractylodes rhizome, 2.0-10.0 parts of radix sophorae flavescentis, 2.0-10.0 parts of radix astragali preparata, 2.0-10.0 parts of rhizoma bambusae, 2.0-15.0 parts of clinopodium herb, 2.0-10.0 parts of anemone rubrum, 2.0-15.0 parts of cherry leaf, 3.0-9.0 parts of hairyvein agrimony and 3.0-9.0 parts of herba hyperici japonici.
2. The preparation for treating vaginitis according to claim 1, which is prepared from the following Chinese medicinal materials in parts by weight: 5.0 to 10.0 parts of stemona root, 5.0 to 10.0 parts of cynanchum atratum, 5.0 to 10.0 parts of rhizoma alismatis, 5.0 to 8.0 parts of bighead atractylodes rhizome, 5.0 to 8.0 parts of sophora flavescens, 4.0 to 8.0 parts of radix astragali preparata, 5.0 to 8.0 parts of rhizopus bambusicola, 5.0 to 10.0 parts of clinopodium herb, 5.0 to 8.0 parts of anemone chinensis, 5.0 to 10.0 parts of cherry leaf, 4.0 to 8.0 parts of hairyvein agrimony and 4.0 to 8.0 parts of hypericum japonicum.
3. The preparation for treating vaginitis according to claim 2, wherein the preparation is prepared from the following Chinese medicinal materials in parts by weight: 7.0 parts of stemona root, 8.0 parts of cynanchum atratum, 6.0 parts of rhizoma alismatis, 7.0 parts of bighead atractylodes rhizome, 6.0 parts of radix sophorae flavescentis, 7.0 parts of radix astragali preparata, 6.5 parts of rhizoma bambusae, 7.5 parts of herba clinopodii, 7.0 parts of gynura bicolor, 8.0 parts of cherry leaf, 6.5 parts of hairyvein agrimony and 6.5 parts of herba hyperici japonici.
4. The preparation for treating vaginitis according to claim 2, wherein the preparation is prepared from the following Chinese medicinal materials in parts by weight: 9.0 parts of stemona root, 7.0 parts of cynanchum atratum, 7.5 parts of rhizoma alismatis, 6.5 parts of bighead atractylodes rhizome, 7.0 parts of radix sophorae flavescentis, 6.0 parts of radix astragali preparata, 7.5 parts of rhizoma bambusae, 8.5 parts of herba clinopodii, 6.0 parts of gynura bicolor, 7.0 parts of cherry leaf, 7.0 parts of hairyvein agrimony and 5.5 parts of herba hyperici japonici.
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