CN102988847A - Medicine composition used for treating vaginitis - Google Patents
Medicine composition used for treating vaginitis Download PDFInfo
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Abstract
The invention relates to a medicine composition used for treating vaginitis, and belongs to the technical field of medicine. The medicine composition is composed of amur corktree bark, common cnidium fruit, sessile stemona root tuber, lightyellow sophora root, flatspine pricklyash, hairyvein agrimonia herb, borneol, and the like. The medicine composition has the functions of heat clearing, detoxifying, dampness eliminating, and disinfecting. The medicine composition is used in treating vaginitis, especially trichomonas vaginitis and mycotic vaginitis. The medicine composition provides a substantial effect in years of clinical applications.
Description
Technical field
The present invention relates to a kind of colpitic pharmaceutical composition for the treatment of, have heat-clearing and toxic substances removing, the effect of removing dampness and killing parasites; The clinical vaginitis that is used for the treatment of.Belong to medical technical field.
Background technology
Vaginitis is that pathogen is invaded vagina, makes vaginal mucosa produce inflammation.Vaginitis belongs to the category of TCM Gynecology " leukorrheal diseases ", " pudendal pruritus ", and common clinically is trichomonal vaginitis, colpitis mycotica, bacterial vaginosis and senile vaginitis Four types.
Trichomonal vaginitis (trichomonal vaginitis) is the common disease of gynecological.It is per vaginam trichomonal.Trichomonal vaginitis can by the sexual intercourse direct contagion, also can pass through common plunge bath, swimming pool, the infect indirectlies such as sitting type toilet seat.Trichomonal vaginitis not only can affect women's daily life, the consequence such as also might lead to complications, infertile, and serious also might bring out precancerous lesion.Therefore, in time treat trichomonal vaginitis.
Colpitis mycotica is that particularly Candida albicans is as a kind of vagina of main pathogens take candidiasis, so be called again the beads vaginitis, its sickness rate has been higher than trichomonal vaginitis at present.Colpitis mycotica patient's main manifestations is leucorrhoea grow in quantity, pudendum, pruritus of vagina, burning sensation, and painful urination, Chang Fahong, edema around the pudendum, epidermis changes varied; Very shallow vesicle pimple can occur; It is rotten to the corn also can to form the eczema shape; Can cause individually small white pustule, ulcer occurs when serious.
Chinese medicine think its cause of disease of vaginitis mainly be in damp-heat accumulation, worm-eaten the moon due to, pathogenesis is the liver,spleen,kidney malfunction and appoints that to be with two arteries and veins to lose solid.Damp and hot heresy has inside and outside dividing.Cause damp and invade outward as occupying for a long time wetland etc., strongly fragrant and heat-transformation, or menstrual period, puerperal, damp and hot evil poison is taken advantage of a weak point in opponent's defence and the people, and this is that diseases caused by exogenous pathogenic factor are damp and hot.If plain body deficiency-weakness of spleen-QI, or depression of liver-QI, wood gram spleen soil, dysfunction of the spleen in transportation stays in water is wet, stops pouring down Jiao, accumulate and heat-transformation, then be that interior life is damp and hot.Damp-heat accumulation, ligament are not solid, and then leukorrhagia increases, yellow skin.With the passing of time the damp contamination becomes poison, or infects the pyretic toxicity pathogen, and as seen the absurd row of intenseness of heat forcing blood, or noxious dampness corrosion skin then are with defecation with blood and pus, or are seen " erosion of the vulva " " erosion of vulva ".Web rot is infested, or health preserving is careless, the evil straight external genitals of violating of worm, causalgia in pudendal pruritus, the moon then in worm-eaten the moon.Primary disease is take damp as trouble, so its disease is touching, repeatedly outbreak is difficult for speed more, Chang Bingfa menoxenia, amenorrhea, the illness such as infertile.Rule together inside and outside taking in the treatment, the men and women rules together, the method effect of continuous use is fine.The direct result of prolonged application metronidazole makes pathogenic bacteria produce drug resistance exactly, destroy the restricting relation between vaginal microbial flora, intravaginal flora is got muddled, mutual inhibitory action is changed, cause conk vigorous, treatment cycle constantly prolongs, and the touching difficulty of inflammation is more brought unnecessary spirit and economic loss to the patient.
Fructus Cnidii temperature in the medicine of the present invention, kidney and enhancing body, killing parasites for relieving itching has the effect of the trichomonas vaginitis killed.The Radix Sophorae Flavescentis heat clearing and damp drying, wind dispelling insecticide, diuresis, Cortex Phellodendri, Herba Agrimoniae, the Radix Stemonae can be strengthened the effect of heat-clearing and toxic substances removing parasite killing, Pericarpium Zanthoxyli parasite killing dispelling wind for relieving itching, the Borneolum Syntheticum heat-clearing and toxic substances removing is antipruritic.All medicines share, and leukorrhagia is controlled in the parasite killing dehumidifying, heat-clearing and toxic substances removing, and the only pudendal pruritus of dispeling the wind has good therapeutical effect to vaginitis.
Through the retrieval prior art, finding has with the similar prior art of patent of the present invention: Dong Li the present invention a kind of external used medicine for the treatment of various gynecological diseases---Fuyanyu.No. 1 powder and capsule cures mainly the multiple gynecologicals diseases such as vulvitis, vaginitis, cervical erosion, cervicitis.Comprise Chinese medicine: Rhizoma Pinelliae, float the Rhizoma Pinelliae, Herba Andrographis, Radix Sophorae Tonkinensis, Radix Arnebiae (Radix Lithospermi), Herba Senecionis Scandentis, Rhizoma Polygoni Cuspidati, Herba Solani Nigri, Fructus Cnidii, dried Alumen, Borneolum Syntheticum.No. 2 capsule for suppository cures mainly the early metaphase cervical cancer, comprises Chinese medicine: Herba Crotalariae sessiliflorae, rhizoma sparganic, Rhizoma Curcumae, Pseudobulbus cremastrae seu pleiones, process arsenic, Realgar, Fructus Cnidii, Borax, Moschus, dried Alumen, Borneolum Syntheticum, Endothelium Corneum Gigeriae Galli.(application (patent) number: CN97112812.X).But compare with medicine of the present invention, drug prescription taste of Chinese medicine of the present invention is few, and is conventional medicine, low price; Preparation technology is simple, and production cost is low, has alleviated patient economy burden.
The colpitic medicine for the treatment of is main mainly with the chemical medicine composition on the existing market, though therapeutic effect is better, produces easily the untoward reaction such as drug dependence and heavy damage vagina internal medium even the vagina inner skin of burning; Medicine of the present invention is pure Chinese medicinal preparation, have no adverse reaction, clinical practice for many years, successful.
Summary of the invention
Pharmaceutical composition of the present invention is to be formed by Chinese drug preparations such as Cortex Phellodendri, Fructus Cnidii, the Radix Stemonae, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli, Herba Agrimoniae, Borneolum Syntheticums, be guiding treatment vaginitis, especially trichomonal vaginitis and colpitis mycotica with the traditional Chinese medical science " heat-clearing and toxic substances removing; removing dampness and killing parasites " theory.
For achieving the above object, the colpitic pharmaceutical composition for the treatment of provided by the invention is prepared from by the processing of the crude drug of following weight parts:
Cortex Phellodendri 20-30 part Fructus Cnidii 15-20 part Radix Stemonae 10-20 part Radix Sophorae Flavescentis 10-20 part
Pericarpium Zanthoxyli 6-10 part Herba Agrimoniae 6-15 part Borneolum Syntheticum 1-3 part.
Preferred plan is prepared from by the processing of the crude drug of following weight parts:
15 parts of 15 parts of Radix Sophorae Flavescentiss of 18 parts of Radixs Stemonae of 25 parts of Fructus Cnidiis of Cortex Phellodendri
2 parts of 12 parts of Borneolum Syntheticums of 8 parts of Herba Agrimoniaes of Pericarpium Zanthoxyli.
The present invention treats colpitic pharmaceutical composition, and external can be treated vaginitis, especially trichomonal vaginitis and colpitis mycotica.
Pharmaceutical composition ingredients modern pharmacological research of the present invention shows:
1. Cortex Phellodendri: heat clearing and damp drying, pathogenic fire purging is except steaming, and skin ulcer is treated in detoxifcation.Its main component berberine hydrochloride has anti-trichomonal, anti-leishmania donovani, anti-trypanosomicide, kill the effect such as paramecium.
2. Radix Sophorae Flavescentis: hardship, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Heat clearing and damp drying, parasite killing, diuresis.Be used for hematodiarrhoea, have blood in stool jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
The matrine that Radix Sophorae Flavescentis contains has active anticancer, oxymatrine has effect in increasing leukocyte, oxymatrine can obviously resist the exudative inflammation that Oleum Tiglii, carrageenin (rat) and glacial acetic acid (mice) bring out, all there is antibacterial action the matrine inside and outside, action intensity is suitable with chloromycetin in the body, the alcohol leaching mastic has the anti-trichomonal effect outward, and its intensity and hops are close.
3. Fructus Cnidii: hot, bitter, temperature; Slightly poisonous.Return kidney channel.Warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, cold womb, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, external treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis.
The xanthotoxol that Fructus Cnidii contains has significant antifungal effect, and Fructus Cnidii also has anti-trichomonal effect, gonadotropic Effect, local anesthetic action, and osthole can suppress the mice passive cutaneous anaphylaxis, PCA strongly.
4. the Radix Stemonae: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Be used for new chronic cough and cough lung impairment and cough, pertussis; Outer for head louse, body louse, enterobiasis, pudendal pruritus disease.
5. Pericarpium Zanthoxyli: suffering, temperature.Return spleen, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching.Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.Pericarpium Zanthoxyli is to 10 kinds of gram positive bacterias such as anthrax bacillus, Hemolytic streptococcus, diphtheria corynebacterium, Diplococcus pneumoniae, staphylococcus aureus, lemon yellow and Staphylococcus albus, bacillus subtilis, and the enteral pathogenic bacterium such as escherichia coli, Song Nei Shi dysentery bar flute, Bacillus proteus, typhoid fever and Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera all have obvious inhibitory action.
6. Herba Agrimoniae: astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, detoxifcation.Be used for hemoptysis, spit blood, metrostaxis, malaria, dysentery is taken off the power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.
7. Borneolum Syntheticum has antiinflammatory action, analgesic effect, antibacterial action: Borneolum Syntheticum can suppress or kill the clinical common bacterias such as staphylococcus aureus, beta hemolytic streptococcus, viridans streptococci.
Clinical observation 85 routine vaginitis patients, trichomonal vaginitis 25 examples wherein, colpitis mycotica 40 examples, bacterial vaginitis 20 examples.Medicine decocting liquid washout of the present invention (every dose of medicine can decoct with 2 times) with it, every day 2 times, a week is a course for the treatment of.Cure altogether in the course for the treatment of and suffer from 66 examples, 15 examples that take a turn for the better, invalid 4 examples.That is to say that medicine of the present invention is 77.6% to colpitic cure rate, total effective rate is 95.3%.
Effect assessment: recovery from illness: dense property or foam sample leucorrhea disappearance pruritus vulvae, frequent micturition dysurea disappear, and be congested without vulvovaginal, and after the treatment, check secretions after each menstruation is clean is through 3 feminine genders of continuous review.Take a turn for the better: leucorrhea reduces, and pruritus vulvae, frequent micturition dysurea symptom take a turn for the better, and pudendum is without hyperemia, and secretions smear for microscopic examination infusorian reduces debility.Invalid: clinical symptoms and sign are without change.Recovery from illness adds up to effectively with improvement.
The specific embodiment
Below with embodiment the colpitic pharmaceutical composition for the treatment of of the present invention is further described, this will help the present invention and effect thereof are further understood, embodiment does not limit protection scope of the present invention, its protection domain is decided by claim.
Embodiment 1
Treating colpitic medicine is comprised of the Chinese crude drug of following weight parts: Cortex Phellodendri 20g, Fructus Cnidii 15g, Radix Stemonae 10g, Radix Sophorae Flavescentis 10g, Pericarpium Zanthoxyli 6g, Herba Agrimoniae 6g, Borneolum Syntheticum 1g.
Above-mentioned medical material adds water 1000ml and fries in shallow oil into 300ml, for patient's washout once; Medicinal residues add water 800ml and fry in shallow oil into the 300ml medicinal liquid, wash once for the patient again.
Embodiment 2
Treating colpitic medicine is comprised of the Chinese crude drug of following weight parts: Cortex Phellodendri 30g, Fructus Cnidii 20g, Radix Stemonae 20g, Radix Sophorae Flavescentis 20g, Pericarpium Zanthoxyli 10g, Herba Agrimoniae 15g, Borneolum Syntheticum 3g.
Above-mentioned medical material adds water 1000ml and fries in shallow oil into 300ml, for patient's washout once; Medicinal residues add water 800ml and fry in shallow oil into the 300ml medicinal liquid, wash once for the patient again.
Embodiment 3
Treating colpitic medicine is comprised of the Chinese crude drug of following weight parts: Cortex Phellodendri 25g, Fructus Cnidii 18g, Radix Stemonae 15g, Radix Sophorae Flavescentis 15g, Pericarpium Zanthoxyli 8g, Herba Agrimoniae 12g, Borneolum Syntheticum 2g.
Above-mentioned medical material adds water 1000ml and fries in shallow oil into 300ml, for patient's washout once; Medicinal residues add water 800ml and fry in shallow oil into the 300ml medicinal liquid, wash once for the patient again.
Below in conjunction with concrete case drug effect of the present invention is described further:
Case 1: the Wang, the woman, 30 years old, summer in 2009 conscious pruritus vulvae, gynecologial examination finds that vaginal wall is congested, the surface is covered with white films sample thing, vaginal secretions is the yellow-white of thickness, is diagnosed as colpitis mycotica.The corresponding method of the prescription of the embodiment 2 of medicine of the present invention and reference decocts washout with it, and every day, washout was 2 times, transference cure after three days.
Case 2: stone, woman, 38 years old, conscious pruritus vulvae when examining, vagina formicant itching, endurable.The visible vagina of gynecologial examination has the petechia, many places, and vaginal secretions is the foam sample, is diagnosed as trichomonal vaginitis.Decoct washout with the prescription of embodiment 3 and with reference to corresponding method, every day, washout was 2 times, transference cure after the week.
Claims (2)
1. treat colpitic pharmaceutical composition for one kind, it is characterized in that being prepared from by the crude drug processing of following weight parts:
Cortex Phellodendri 20-30 part Fructus Cnidii 15-20 part Radix Stemonae 10-20 part Radix Sophorae Flavescentis 10-20 part
Pericarpium Zanthoxyli 6-10 part Herba Agrimoniae 6-15 part Borneolum Syntheticum 1-3 part.
2. a kind of colpitic pharmaceutical composition for the treatment of according to claim 1 is characterized in that being prepared from by the crude drug processing of following weight parts:
15 parts of 15 parts of Radix Sophorae Flavescentiss of 18 parts of Radixs Stemonae of 25 parts of Fructus Cnidiis of Cortex Phellodendri
2 parts of 12 parts of Borneolum Syntheticums of 8 parts of Herba Agrimoniaes of Pericarpium Zanthoxyli.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524845A (en) * | 2018-06-22 | 2018-09-14 | 李秀勤 | The stifled logical liquid of the external application Chinese medicine stasis of blood |
| CN112043802A (en) * | 2020-10-26 | 2020-12-08 | 河南健悦生物科技有限公司 | Preparation for treating vaginitis |
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2011
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108524845A (en) * | 2018-06-22 | 2018-09-14 | 李秀勤 | The stifled logical liquid of the external application Chinese medicine stasis of blood |
| CN112043802A (en) * | 2020-10-26 | 2020-12-08 | 河南健悦生物科技有限公司 | Preparation for treating vaginitis |
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Application publication date: 20130327 |