CN112014552A - Detection device - Google Patents

Abstract

The invention discloses a detection device, which comprises a first cavity for collecting a sample, a second cavity for retaining the sample and a sealing element, wherein the first cavity is positioned in a cup body, the second cavity is positioned in a sample bottle, the sample bottle is detachable, and the second cavity can be independent of the device; the sealing element comprises two operating positions: the sealing element comprises a first working position and a second working position, and when the sealing element is in the first working position, the second cavity is communicated with the first cavity; when the sealing element is in the second working position, the second cavity is not communicated with the first cavity; the device comprises two working states: a standing state and a pouring state. The detection device has the function of collecting samples into the sample bottle for secondary detection, and the sample bottle can be independently detached from the interior of the detection device, so that the purity of the retained samples is ensured; the device can be placed on a desktop in a toppling mode, and the test element in the cup body is displayed in an inclined and upward mode, so that an operator can read results conveniently.

Description

a detection device

technical field

The present invention relates to a detection device, in particular to a device capable of collecting, detecting and retaining samples.

Background technique

The following description of the background art is only the introduction of some background common sense, and will not constitute any limitation to the present invention.

At present, detection devices for detecting whether a sample contains analyte substances are widely used in hospitals or at home. These detection devices for rapid diagnosis include one or more detection reagent strips, such as early pregnancy detection, drug abuse detection, etc. Wait. This kind of rapid diagnosis detection device is very convenient, and the detection result can be obtained on the detection reagent strip in one minute, or at most ten minutes.

Drug detection is widely used, and is often used in anti-drug departments, public security bureaus, drug rehabilitation centers, physical examination centers, national military recruitment physical examination offices and other institutions. There are various types of drug testing and frequent frequency, and there is a huge market demand for drug testing urine cups that can automatically separate the remaining samples from the tested samples.

In the prior art, there are a large number of disposable detection devices that integrate collection and detection. For example, as described in Chinese Patent No. 2008103055231, it includes a cup body. The side of the cup body is provided with a test board containing test paper, and the cup body and the test board are located. The area can be connected. As described in paragraph 0005 of the description of the document, the tested person places urine in the urine cup. At this time, the positioning component controls the liquid outlet on the test board to not communicate with the communication hole on the cup body. When the inspector needs to perform the inspection, the inspector adjusts the positioning component, connects the liquid outlet with the communication hole, and at the same time inverts the cup body, the urine flows into the test strip cavity, and starts the reaction autonomously. After the reaction is completed, the results are interpreted and recorded, and the urine cup is placed upright, thereby realizing the separation of the urine in the detection area and the urine in the urine cup. Although the detection device can realize the separation of the urine in the detection area and the urine in the urine cup, the form of this separation is not complete, and the separation of the urine in the detection area and the urine in the urine cup is substantially Still in the same detection device, which is very inconvenient. For example: the operator needs to keep a sample of the urine in the urine cup for subsequent secondary testing. At this time, he will either save it together with the testing area (whether the test agent in the testing area will produce and/or volatilize substances) Affect the urine in the urine cup, which we do not know); or extract part of the urine in the urine cup and store it in another collection container (although this method can ensure that the sample is not contaminated, the operation is relatively cumbersome).

In view of the above technical problems, it is necessary to improve them and provide another way to solve the deficiencies of the existing traditional technology.

SUMMARY OF THE INVENTION

The technical problem to be solved by the present invention is to provide a detection device for solving the above-mentioned technical problems.

The technical solution adopted by the present invention to solve the above technical problems is as follows: a detection device, comprising a first cavity for collecting samples, a second cavity for retaining samples, and a sealing element, the first cavity is located in the cup body, and the second cavity is located in the cup body. Located in the sample bottle, the sample bottle is detachable, and the second cavity can be independent from the outside of the device;

The sealing element includes two working positions: a first working position and a second working position. When the sealing element is in the first working position, the second cavity is in a communication state with the first cavity; when the sealing element is in the second working position, the first The second cavity is in a non-communication state with the first cavity;

The device includes two working states: an upright state and a dumped state.

Further, it also includes a first cover body, the first cover body is detachably connected with the cup body, and the space formed by the assembly of the first cover body and the cup body is a first cavity.

Further, the cup body is provided with a first channel, the sample bottle includes a bottle mouth, and the first channel can extend into the bottle mouth.

Further, the first cover body is provided with a second channel, the sample bottle includes a bottle mouth, and the second channel can extend into the bottle mouth.

Further, the cup body is provided with a first channel, the sample bottle includes a bottle mouth, the first channel extends into the bottle mouth, the first cover is provided with a second channel, the second channel is opposite to the first channel, and the sealing element can be inserted into the first and second channels.

Further, the cup body is located on one side of the first channel and is provided with a blank area, and the blank area is used for installing the sample bottle.

Further, the first channel and the second channel are both cylindrical channels, the inner diameter of the first channel is the same as the inner diameter of the second channel, a second cover body is detachably connected to the second channel, and the second cover body can be closed. sample bottle.

Further, the first cover body is provided with a buckle, and the buckle can fix the sealing element.

Further, the first cavity is provided with a test element capable of detecting the sample, and the test element can be read when the device is in a pouring state.

Further, when the device is in a poured state and the first working position of the device is sealed, the sample in the first cavity can enter the second cavity.

The beneficial effects of the present invention are: the detection device of the present invention has the function of collecting samples into a sample bottle for secondary detection in addition to the basic function of collecting and detecting samples, and the sample bottle can be detached from the detection device separately. Therefore, the sample in the sample bottle must not be affected by the test element in the detection device to ensure the purity of the retained sample; the device can be poured on the table, and the test element in the cup body is displayed tilted upward, which is convenient for the operator to directly To read the results, compared with the common detection device that needs to be picked up to read the results, the device is more convenient to read the results, especially when the operator records a large number of device test results, he can have a lot of time left; , in the pouring state, the device can automatically retain the sample, and the sample in the first cavity can enter the second cavity, which reduces the subsequent steps of removing the sample bottle and improves the detection efficiency; the detection device of the present invention is designed Sophisticated, simple to use and easy to operate.

Description of drawings

1 is a schematic diagram of the overall structure of a detection device;

Fig. 2 is the sectional view of Fig. 1;

Fig. 3 is the exploded view of Fig. 1;

Fig. 4 is a kind of schematic diagram when the detection device adds the sample;

Figure 5 is a cross-sectional view of a detection device in an overturned state;

6 is a cross-sectional view of the sealing element after sealing the first channel and the second channel;

Figure 7 is a schematic view of the sample vial after separation from the device.

Detailed Description

The structures involved in the present invention or the technical terms used are further described below. If there is no special indication, they should be understood and interpreted according to the general terms commonly used in the art.

detect

Detection means assaying or testing for the presence of a substance or material such as, but not limited to, chemicals, organic compounds, inorganic compounds, metabolites, drugs or drug metabolites, organic tissue or metabolites of organic tissue, nucleic acids, protein or polymer. In addition, detection refers to the quantity of a test substance or material. Further, the assay also means immunoassay, chemical assay, enzymatic assay, and the like.

sample

Detection devices or collected samples of the present invention include biological fluids (eg, patient fluids or clinical samples). Liquid samples or liquid samples, or fluid samples or fluid samples, can be derived from solid or semi-solid samples, including excreta, biological tissue and food samples. A solid or semi-solid sample can be converted to a liquid sample by any suitable method, such as mixing, mashing, macerating, incubating, dissolving or using enzymes in a suitable solution (eg water, phosphate solution or other buffer solution) Digestion of solid samples. "Biological samples" include animal, plant and food samples, including, for example, urine, saliva, blood and components thereof, spinal fluid, vaginal secretions, sperm, feces, sweat, secretions, tissues, of human or animal origin, Organs, tumors, tissues and organ cultures, cell cultures and media. Preferably the biological sample is urine, preferably the biological sample is saliva. Food samples include food-processed substances, final products, meat, cheese, wine, milk and reference water. Plant samples include those derived from any plant, plant tissue, plant cell culture and media. "Environmental samples" are derived from the environment (eg, liquid samples from lakes or other bodies of water, sewage samples, soil samples, groundwater, seawater, and waste liquid samples). Environmental samples may also include sewage or other waste water.

test element

The so-called "test element" here refers to the element that can detect the sample or whether the sample contains the analyte of interest. It can be called the test element. This detection is based on whatever technical principle, immunology, chemistry, electricity, Optical, molecular, nucleic acid, physics, etc. The test element can be selected as a lateral flow test strip, which can detect a variety of analytes. Of course, other suitable test elements can also be used in the present invention.

Various test elements can be used in combination with the present invention. One form is test strips. Test strips for analysis of analytes (eg, drugs or metabolites indicative of medical conditions) in a sample can be in various formats, such as in the form of immunoassays or chemical assays. The test strips can be analyzed in a non-competitive or competitive mode. The test strip generally includes a water-absorbing material with a sample application area, a reagent area and a test area. Add the sample to the sample application area and flow to the reagent area by capillary action. In the reagent area, the sample binds to the reagent if the analyte is present. The sample then continues to flow to the detection zone. Other reagents, such as molecules that specifically bind to the analyte, are immobilized in the detection zone. These reagents react with the analyte (if present) in the sample and bind the analyte in this zone, or bind to one of the reagents in the reagent zone. The label used to display the detection signal is present in the reagent zone or separate label zone.

In a typical non-competitive assay mode, a signal is generated if the analyte is present in the sample, and no signal is generated if the analyte is not present. In the competition method, a signal is generated if the analyte is not present in the sample, and no signal is generated if the analyte is present.

The test element can be a test paper, and a material that absorbs or does not absorb water can be selected. Test strips can include a variety of materials for liquid sample transfer. One of the test paper materials can be overlaid on another material, such as filter paper overlaid on a nitrocellulose membrane. One area of the test strip can be selected from one or more materials, while the other area can be selected from other different materials or materials. Test strips can be adhered to a support or hard surface to improve the strength of the test strips.

The analyte is detected by a signal generating system, such as using one or more enzymes that specifically react with the analyte, using the method of immobilizing the specific binding substance on the detection test paper as described above, and combining one or more enzymes. The composition of the signal generating system is immobilized on the analyte detection area of the test strip. The signal-generating substance may be in the sample application area, the reagent area, or the detection area, or the entire test strip, and the substance may impregnate one or more materials of the test strip. The signal-containing solution is added to the surface of the test paper or one or more materials of the test paper are immersed in the signal-containing solution. The test paper to which the signal containing solution was added was allowed to dry.

The various areas of the test strip can be arranged in the following ways: sample addition area, reagent area, detection area, control area, determination of whether the sample is adulterated or not, and liquid sample absorption area. The control area is located after the detection area. All zones can be arranged on a strip of test strips using only one material. It is also possible to use different materials for different zones. Each zone can be in direct contact with the liquid sample, or different zones can be arranged according to the direction of the liquid sample flow, and the end of each zone can be connected and overlapped with the front end of another zone. The material used can be a material with better water absorption such as filter paper, glass fiber or nitrocellulose membrane. Test strips can also take other forms.

The commonly used reagent strips are nitrocellulose membrane reagent strips, that is, the detection area includes a nitrocellulose membrane, and specific binding molecules are immobilized on the nitrocellulose membrane to display the detection results; it can also be a cellulose acetate membrane or a nylon membrane, etc. . For example, the following patents describe reagent strips or devices containing reagent strips: US 4,857,453; US 5,073,484; US 5,119,831; US 5,185,127; US 5,275,785; US 5,766,961; US 5,770,460; US 5,916,815; US 5,976,895; US 6,248,598; US 6,140,136; The test strips disclosed in the above patent documents and similar devices with test strips can be applied to the test element or detection device of the present invention to detect the analyte, such as the detection of the analyte in the sample.

The detection reagent strips used in the present invention may be so-called lateral flow test strips. The specific structures and detection principles of these detection reagent strips are well known to those skilled in the art in the prior art. A common detection reagent strip includes a sample collection area or a sample application area, a labeling area, a detection area and a water absorption area. The sample collection area includes a sample receiving pad, and the labeling area includes a labeling pad. Including the necessary chemical substances that can detect whether the analyte is contained, such as immunological reagents or enzymatic chemical reagents. The commonly used detection reagent strips are nitrocellulose membrane reagent strips, that is, the detection area includes a nitrocellulose membrane, and specific binding molecules are immobilized on the nitrocellulose membrane to display the detection results; it can also be a cellulose acetate membrane or a nylon membrane, etc. Etc., of course, a detection result control area may also be included downstream of the detection area. Usually, the control area and the detection area appear in the form of horizontal lines, which are detection lines or control lines. Such detection reagent strips are traditional reagent strips, and of course, other types of reagent strips that utilize capillary action for detection can also be used. In addition, the general detection reagent strip has dry chemical reagent components, such as immobilized antibodies or other reagents. When encountering liquid, the liquid flows along the reagent strip with capillary action, and with the flow, the dry reagent components are dissolved in the The liquid, thus proceeding to the next zone for processing, reacts with the dry reagents in that zone to perform the necessary detection. Liquid flow occurs primarily through capillary action. All of these can be applied to the detection device of the present invention, or are arranged in the first chamber to contact the liquid sample, or used to detect the presence or quantity of the analyte in the liquid sample entering the first chamber.

Except that the reagent strip described above or the lateral flow reagent strip itself is used to contact the liquid sample to test whether the liquid sample contains the analyte. In some preferred ways, the test elements can also be arranged on some carriers. For example, in the present invention, as shown in FIG. 2 , the carrier 40 has many grooves 43 for installing the test elements, and the test elements are reagent strips. . Generally, the reagent strip includes a sample application area, a marking area and a detection area. The reagent strip is located in the groove 43. When placing the reagent strip, the sample application area is placed on the opening side of the groove 43, and then the groove 43 is slightly exposed. At one point, a portion of the sample application area is reserved for absorbing liquid samples. Typically, the sample application area is located upstream of the labeling area, and the labeling area is located upstream of the detection area. In some ways, the reagent strips in each groove 43 are different, and one analyte can be detected separately. The groove 43 has an installation sharp corner 45, which can be stuck when the reagent strip is installed to prevent the reagent strip from falling off. In some ways, after the reagent strip is installed in the groove 43 of the carrier 40, a transparent film is covered on the carrier 40, and the film can also prevent the reagent strip from falling off, and the film seals the groove 43 area of the carrier 40, In addition, the transparent film is easy to observe the final test results. The transparent film can also be a transparent plastic sheet, as long as the plastic sheet is transparent in the marked area of the reagent strip.

analyte

Examples of analytes that can be used in the present invention include small molecules, including drugs (eg, drugs of abuse). "Substance of Abuse" (DOA) refers to the use of drugs (usually to paralyze nerves) for non-medical purposes. Abuse of these drugs can lead to physical and mental damage, dependence, addiction and/or death. Examples of drugs of abuse include cocaine; amphetamines AMP (eg, black beauty, white amphetamine tablets, dextroamphetamine, dextroamphetamine tablets, Beans); methamphetamine MET (crank, methamphetamine, crystal , speed); barbiturates BAR (eg, Valium, Roche Pharmaceuticals, Nutley, New Jersey); sedatives (ie, sleep aids); lysergic acid diethylamide (LSD); inhibitors (downers, goofballs, barbs, blue devils, yellow jackets, meprodol); tricyclic antidepressants (TCA, i.e. imipramine, amitriptyline, and doxepin); MDMA; phencyclidine pyridine (PCP); tetrahydrocannabinol (THC, pot, dope, hash, weed, etc.); opiates (i.e. morphine MOP or, opium, cocaine COC; heroin, oxycodone); Anxiety drugs and sedative-hypnotics, anti-anxiety drugs are a class of drugs mainly used to reduce anxiety, tension, fear, stabilize emotions, and have both hypnotic and sedative effects, including benzodiazepines BZO (benzodiazepines), atypical BZ, Fusion diazepine NB23Cs, benzoazepines, ligands for BZ receptors, ring-opening BZs, diphenylmethane derivatives, piperazine carboxylates, piperidine carboxylates, quinazolinones, Thiazine and thiazole derivatives, other heterocycles, imidazole-type sedative/analgesics (such as oxydihydrocodeinone OXY, methadone MTD), propylene glycol derivatives - carbamates, aliphatic compounds, anthracene derivatives Wait. The detection kit of the present invention can also be used for the detection of overdose which belongs to medical use but is easy to take, such as tricyclic antidepressants (imipramine or the like) and acetaminophen. These drugs are metabolized into small molecular substances after being absorbed by the human body. These small molecular substances exist in blood, urine, saliva, sweat and other body fluids or in some body fluids.

For example, analytes detected with the present invention include, but are not limited to, creatinine, bilirubin, nitrite, proteins (non-specific), hormones (eg, human villi-stimulating hormone, progesterone hormone, follicle stimulating hormone, etc. ), blood, leukocytes, sugars, heavy metals or toxins, bacterial substances (such as proteins or carbohydrates against specific bacteria, such as e.g. Escherichia coli 0157:H7, Staphylococcus, Salmonella, Clostridium, Campylobacter, L. monocytogenes, Vibrio, or Cactobacillus) and urine samples for substances related to physiological characteristics, such as pH and specific gravity. Any other clinical urine chemical analysis can be detected in the form of lateral lateral flow detection with the device of the present invention.

Cup body and first cup lid

3, a detection device includes a cup body 10 and a first cover body 20, the first cover body 20 is used to cover the cup body 10, the first cover body 20 is detachably connected with the cup body 10, and the cup body 10 A first cavity 11 is provided inside, the first cavity 11 includes a first opening, and the first cavity 11 can also be called a detection cavity, which is used to detect the analyte in the sample. When the first cover body 20 covers the cup body 10 , the first cavity 11 is sealed to avoid leakage of the sample. Specifically, the cup body 10 and the first cover body 20 are connected by threaded fitting, which is a technical means commonly used in the field and has a good sealing effect on the sample.

Preferably, referring to FIG. 2 , the test elements are located in the first cavity 11, and different test elements are arranged in the grooves 43 of the carrier 40. When the detection device leaves the factory, the test elements are installed in the first cavity 11. It cannot be removed, which can prevent the test element from being replaced without authorization. Specifically, the cup body 10 includes a cup bottom 13 and a cup mouth 12, the cup bottom 13 and the cup mouth 12 are connected by ultrasonic welding, and the contact position between the upper side of the cup bottom 13 and the lower side of the cup mouth 12 is set as flat as possible, which is convenient for ultrasonic waves. Welding takes place.

first chamber and second chamber

The second cavity 31 is arranged in the sample bottle 30, and the second cavity 31 can also be called a sample retention cavity, which is used for retaining the sample for secondary detection. By connecting the second cavity 31 with the first cavity 11, and allowing some samples to enter In the second cavity, the sample retention is completed; the sample bottle 30 is detachable, and the second cavity 31 can be independent from the outside of the device, that is, the second cavity 31 is separated from the first cavity 11 . Specifically, referring to FIG. 2 , the cup body 10 is provided with a first channel 14 , the direction of the first channel 14 is downward, the sample bottle 30 includes a bottle mouth 32 , and the first channel 14 can extend into the bottle mouth 32 . The device includes two working states: the upright state and the pouring state. With reference to Figures 2 and 5, when the device is in the upright state, the sample in the first chamber 11 cannot enter the second chamber under the action of gravity. 31; when the device is in the pouring state, the sample in the first chamber 11 will enter the second chamber 31 by itself under the action of gravity.

Referring to FIG. 5, when the device is in an overturned state, the device can be placed on the table stably. At this time, the test elements in the cup body 10 are displayed inclined upward, which is convenient for the operator to directly read the results. It is more convenient for the device to read the results, especially when the operator records a large number of device test results, there is a lot of time left; in addition, in the dumping state, the device can automatically carry out sample testing. When the sample is retained, the sample in the first cavity 11 can enter the second cavity 31 , which reduces the subsequent steps of removing the sample bottle 30 and improves the detection efficiency.

Preferably, the cup body 10 is provided with a blank area 15 on one side of the first channel 14, and the blank area 15 provides enough space for the installation of the sample bottle 30, so that the sample bottle 30 installed on the cup body 10 does not appear obtrusive , but also helps to improve the stability of the device when placed.

Preferably, as an alternative to “the sample bottle 30 is detachably connected to the cup body 10”, the sample bottle 30 can also be detachably connected to the first cover 20. Specifically, the first cover 20 is provided with a second Channel 21, the direction of the second channel 21 is upward, and the second channel 21 can extend into the bottle mouth 32. At this time, the device includes two working states: the upright state and the inverted state. When the device is in the upright state, the first The sample in the first chamber 11 cannot enter the second chamber 31 under the action of gravity; when the device is in an upside-down state, the sample in the first chamber 11 will automatically enter the second chamber 31 under the action of gravity. In this technical solution, compared with the technical solution of "the sample bottle 30 is detachably connected to the cup body 10", when the device is in the dumping state, the automatic sample retention of the sample cannot be completed. The inversion operation of the device requires one more step, which is relatively cumbersome. Therefore, the above-mentioned technical solution of "the sample bottle 30 is detachably connected to the cup body 10" is preferred.

Preferably, there are many ways for the sample bottle 30 to be detachably connected to the cup body 10 or the first cover body 20. The simplest way is to set the bottle mouth 32 of the sample bottle 30 on the first channel 14 or the second The outer side of the channel 21 can also be directly pulled out of the sample bottle 30 when it needs to be removed, which is convenient and fast; the detachable connection can also be made by setting an external thread on the first channel 14 or the second channel 21 or Correspondingly, a corresponding external thread or an internal thread is set at the position of the bottle mouth 32 of the sample bottle 30 to realize the threaded connection between the channel and the sample bottle 30. In this way, the sample bottle 30 and the cup body 10 or The connection of the first cover body 20 is relatively firm, and it is not easy to fall off.

First cavity, second cavity and sealing element

The detection device further includes a sealing element, and the function of the sealing element is to seal the channel that originally extended into the bottle mouth 32 when the sample bottle 30 is removed, that is, after the sample bottle 30 is removed separately, the cup body 10 will not leakage of samples. Further, the sealing element can be inserted into the channel, whether the sample bottle 30 is detachably connected to the cup body 10 or the sample bottle 30 is detachably connected to the first cover 20, the sealing element can be inserted into the first cover body 20. The channel 14 or the second channel 21 is used to seal the cup body 10 after the sample bottle 30 is disassembled. The sealing element includes two working positions: the first working position and the second working position. The first working position is essentially the position where the sealing element does not enter the channel, and the second cavity 31 is in a communication state with the first cavity 11 at this time; The second working position is essentially the position where the sealing element enters the channel. At this time, the communication relationship between the channel and the first cavity 11 is blocked by the sealing element, so that the second cavity 31 and the first cavity 11 are in a non-communication state. Specifically, when the above-mentioned "sample bottle 30 is detachably connected to the cup body 10", the sealing element can seal the first channel 14; when the above-mentioned "sample bottle 30 is detachably connected to the first cover 20", the sealing element can seal The second channel 21 .

As a preferred technique, referring to FIG. 2 and FIG. 6 , the first cover 20 is provided with a buckle 22 , and the sealing element 50 can be fixed on the buckle 22 , and the sealing element 50 is in the first working position. The cup body 10 is provided with a first channel 14 , the sample bottle 30 includes a bottle mouth 32 , the first channel 14 extends into the bottle mouth 32 , the first cover 20 is provided with a second channel 21 , and the second channel 21 is connected to the first channel 21 . The channel 14 is facing directly, and the second channel 21 is provided so that the sealing element 50 can also seal the first channel 14 when the first channel 14 is fixed to the bottle mouth 32 . When the sealing element 50 is disassembled from the buckle 22, the sealing element 50 can be inserted into the first channel 14 and the second channel 21, the state at this time is referring to FIG. 6, the sealing element 50 is in the second working position, the second The cavity 31 is in a communication state with the first cavity 11 . Specifically, the first channel 14 and the second channel 21 are both cylindrical channels, the inner diameter of the first channel 14 is the same as the inner diameter of the second channel 21 , the sealing element 50 is cylindrical, and its radius is the same as that of the first channel 14 and the second channel 21 . The channel 21 is the same, and the sealing element 50 can completely seal the first channel 14 and the second channel 21 .

After the second cavity 31 is filled with samples, the sealing element 50 is used to cut off the connection between the second cavity 31 and the first cavity 11. Since the second cavity 31 is full of samples, the solid sealing element 50 is used to enter the first channel. During the process of 14, since the gas or the sample cannot be discharged, it will be difficult for the sealing element 50 to enter the first channel 14. Preferably, the sealing element 50 is made of a hollow cylinder first, and the hollow cylinder can solve the problem that the gas or the sample cannot be discharged. Technical problem, meanwhile, the hollow cylindrical sealing element 50 can reduce the weight of the sealing element 50 and the manufacturing cost of the device.

Since the first cover 20 is provided with a second channel 21, referring to FIG. 5, if the second channel 21 is not sealed, the sample will leak from the second channel 21. Preferably, the second channel 21 is detachable. The second cover body 33 is connected. After the sealing element 50 seals the first channel 14 and the second channel 21 , the second cover body 33 can be used to cover the sample vial 30 , as shown in FIG. 7 .

In order to make it easier for technicians to understand the technical solutions of the present invention, the following assembly process is given in conjunction with the detection device provided by the present invention. Referring to Figures 1 to 3 , the operator first assembles the first cover 20 and the cup body 10 After screwing, the sealing element 50 is fixed to the buckle 22, the second cover 33 is fixed to the second channel 21, and the sample bottle 30 is fixed to the first channel 14 through the bottle mouth 32 to complete the assembly.

The method of use is described below: referring to Figures 4-7, unscrew the first cover 20, add the sample into the first cavity 11, cover the first cover 20, realize the sampling operation, and test the sample and the first cavity 11 The element makes contact and the test element performs the detection of the analyte. The operator dumps the device, the device is in the dumping state, and the side of the test element in the cup body 10 is displayed tilted upward. At this time, the device is placed stably on the table. As shown in FIG. 5, the operator can directly read the results. Meanwhile, in the pouring state, the sample in the first cavity 11 enters into the second cavity 31 through the first channel 14 to complete the sample retention operation. Referring to FIG. 6 , the operator puts the device upright again, removes the sealing element 50 from the buckle 22 , removes the second cover 33 from the second channel 21 , and then inserts the sealing element 50 through the second channel 21 Into the first channel 14, the sealing element 50 seals the first channel 14 and the second channel 21, and the first cavity 11 and the second cavity 31 are in a non-communication state. The operator then removes the sample vial 30, and uses the second cap body 33 to cover the sample vial 30, as shown in FIG. 7 . The operator can also secure the sample vial 30 to the catch 22 if desired.

The above are only specific embodiments of the invention, but the protection scope of the invention is not limited to this. Any changes or substitutions that are not thought of through creative work, or some simple changes in operation procedures, should be covered by the protection of the invention. Therefore, the protection scope of the invention should be subject to the protection scope defined by the claims.

The invention shown and described herein may be practiced in the absence of any element, limitation, specifically disclosed herein. The terms and expressions employed are to be used as terms of description rather than limitation and it is not intended that the use of these terms and expressions exclude any equivalents of the features shown and described, or parts thereof, and it should be recognized that each Both modifications are possible within the scope of the present invention. It should therefore be understood that while the invention has been specifically disclosed by various embodiments and optional features, modifications and variations of the concepts described herein may be employed by those of ordinary skill in the art and are considered to fall within the scope of It is within the scope of the invention as defined in the appended claims.

The contents of articles, patents, patent applications, and all other documents and electronically available information described or recorded herein are hereby incorporated by reference in their entirety to the same extent as if each individual publication was specifically As if indicated separately for reference. Applicants reserve the right to incorporate into this application any and all materials and information from any such articles, patents, patent applications or other documents.

Claims (10)

1. A detection device, characterized in that it comprises a first cavity for collecting samples, a second cavity for retaining samples and a sealing element, the first cavity is located in a cup body, the second cavity is located in a sample bottle, the sample bottle is located being detachable, the second chamber can be independent from the outside of the device; The sealing element includes two working positions: a first working position and a second working position. When the sealing element is in the first working position, the second cavity is in a communication state with the first cavity; when the sealing element is in the second working position, the first The second cavity is in a non-communication state with the first cavity; The device includes two working states: an upright state and a dumped state. 2 . The detection device according to claim 1 , further comprising a first cover body, the first cover body and the cup body are detachably connected, and the first cover body and the cup body are assembled together to form a The space is the first cavity. 3 . The detection device according to claim 1 , wherein the cup body is provided with a first channel, the sample bottle includes a bottle mouth, and the first channel can extend into the bottle mouth. 4 . 4 . The detection device according to claim 2 , wherein the first cover body is provided with a second channel, the sample bottle includes a bottle mouth, and the second channel can extend into the bottle mouth. 5 . 5. The detection device according to claim 2, wherein the cup body is provided with a first channel, the sample bottle includes a bottle mouth, the first channel extends into the bottle mouth, and the first cover is provided with a second channel , the second channel is opposite to the first channel, and the sealing element can be inserted into the first channel and the second channel. 6 . The detection device according to claim 3 or 5 , wherein the cup body is located on one side of the first channel with a blank area, and the blank area is used for installing the sample bottle. 7 . 7. A detection device according to claim 6, wherein the first channel and the second channel are both cylindrical channels, the inner diameter of the first channel is the same as the inner diameter of the second channel, and the second channel is detachable A second cover body is connected to the type, and the second cover body can cover the sample bottle. 8 . The detection device according to claim 4 or 7 , wherein the first cover is provided with a buckle, and the buckle can fix the sealing element. 9 . 9 . The detection device according to claim 1 , wherein a test element capable of detecting the sample is provided in the first cavity, and the test element can be read when the device is in a pouring state. 10 . 10 . The detection device according to claim 1 , wherein the sample in the first cavity can enter into the second cavity when the device is in a poured state and the first working position of the sealing device is sealed. 11 .

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