CN111743873A - Medicated bath traditional Chinese medicine composition and preparation and application thereof - Google Patents
Medicated bath traditional Chinese medicine composition and preparation and application thereof Download PDFInfo
- Publication number
- CN111743873A CN111743873A CN202010778324.3A CN202010778324A CN111743873A CN 111743873 A CN111743873 A CN 111743873A CN 202010778324 A CN202010778324 A CN 202010778324A CN 111743873 A CN111743873 A CN 111743873A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- traditional chinese
- medicine composition
- medicated bath
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 69
- 239000000203 mixture Substances 0.000 title claims abstract description 69
- 238000002360 preparation method Methods 0.000 title claims abstract description 30
- 239000002994 raw material Substances 0.000 claims abstract description 29
- 241000366182 Melaleuca alternifolia Species 0.000 claims abstract description 19
- 208000003251 Pruritus Diseases 0.000 claims abstract description 18
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims abstract description 11
- 235000003097 Artemisia absinthium Nutrition 0.000 claims abstract description 11
- 240000001851 Artemisia dracunculus Species 0.000 claims abstract description 11
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims abstract description 11
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims abstract description 11
- 241001504070 Huperzia Species 0.000 claims abstract description 11
- 239000001138 artemisia absinthium Substances 0.000 claims abstract description 11
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 11
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 10
- 240000000249 Morus alba Species 0.000 claims abstract description 10
- 239000000843 powder Substances 0.000 claims description 26
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 18
- 239000000706 filtrate Substances 0.000 claims description 17
- 239000007938 effervescent tablet Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000000463 material Substances 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 9
- 238000009777 vacuum freeze-drying Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 239000002202 Polyethylene glycol Substances 0.000 claims description 6
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 claims description 6
- 229920001223 polyethylene glycol Polymers 0.000 claims description 6
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 6
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 6
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 6
- 206010061218 Inflammation Diseases 0.000 claims description 4
- 239000002552 dosage form Substances 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 3
- 239000013040 bath agent Substances 0.000 claims description 3
- 241000246044 Sophora flavescens Species 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 230000003860 sleep quality Effects 0.000 abstract description 8
- 230000000694 effects Effects 0.000 description 20
- 230000007803 itching Effects 0.000 description 9
- 238000001035 drying Methods 0.000 description 6
- 239000000047 product Substances 0.000 description 6
- 244000045947 parasite Species 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 230000003213 activating effect Effects 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 230000002040 relaxant effect Effects 0.000 description 4
- 238000007873 sieving Methods 0.000 description 4
- 210000002435 tendon Anatomy 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 3
- 230000003467 diminishing effect Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000002791 soaking Methods 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- 238000003287 bathing Methods 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- 239000002195 soluble material Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 1
- 241000735527 Eupatorium Species 0.000 description 1
- 229920002582 Polyethylene Glycol 600 Polymers 0.000 description 1
- 206010062519 Poor quality sleep Diseases 0.000 description 1
- 241001671204 Stemona Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000036299 sexual function Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of traditional Chinese medicine compositions, in particular to a medicated bath traditional Chinese medicine composition and preparation and application thereof. The medicated bath traditional Chinese medicine composition provided by the invention is prepared from the following raw materials in parts by mass: 30-100 parts of melaleuca alternifolia, 10-25 parts of beefwood-like clubmoss herb, 1-15 parts of mulberry leaf, 1-15 parts of radix sophorae flavescentis, 3-20 parts of wormwood, 1-10 parts of radix stemonae and 1-25 parts of fructus kochiae. The medicated bath traditional Chinese medicine composition provided by the invention can effectively treat skin itch of patients and improve the sleep quality of patients.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine compositions, in particular to a medicated bath traditional Chinese medicine composition and preparation and application thereof.
Background
The medicated bath has unique efficacy on human body and is always valued by the medical field since ancient times. Adding Chinese liquor and white vinegar before bathing can also promote health, such as cleaning body and relieving fatigue, treating hemorrhoid and constipation, and improving sexual function. Medicated baths have been in china for thousands of years. It is described that the fragrant bath is popular from the beginning of the week. The fragrant soup is the liquid medicine decocted by the traditional Chinese medicine eupatorium. The product has fragrant smell, and has effects of relieving summer heat, eliminating dampness, refreshing brain. From the beginning of the Qing Dynasty, medicated bath is advocated by doctors as an effective method for preventing and treating diseases, and the therapy can be introduced into the lives of ordinary people.
The traditional Chinese medicine medicated bath integrates the treatment methods of disease prevention, disease treatment, body perfuming, body shaping, health care and body building, and is not distinguished to be precious and widely adopted from ancient times to the present. The general theory of action mechanism of medicated bath is that the herbs act on the superficial, local and affected parts of the body, and absorbed by the channels, travel along the meridians and blood vessels, and reach the zang-fu organs from the exterior to the interior, thus producing the therapeutic effect. The traditional Chinese medicine bath products in the market at present are various in types, and although most products have the effects of inhibiting bacteria, relieving itching, relieving fatigue and improving sleep, the effects are weak, and the treatment effect is not ideal. In addition, in the traditional Chinese medicine skin-nourishing products developed by taking melaleuca alternifolia as a raw material in the prior art, such as 'a traditional Chinese medicine solution for skin diseases and a preparation method thereof' (CN 110755533A), the traditional Chinese medicine skin-nourishing products have the defects of complex preparation process and single effect, and are not suitable for patients with skin pruritus, difficult sleep and other symptoms in the common population.
Disclosure of Invention
In order to solve the problems, the invention provides a medicated bath traditional Chinese medicine composition and preparation and application thereof. The medicated bath traditional Chinese medicine composition provided by the invention has obvious drug effect and multiple curative effects, such as bacteriostasis, skin nourishing, tendon relaxing, collateral activating, heart calming, nerve soothing and the like.
In order to achieve the purpose, the invention provides the following technical scheme:
the invention provides a medicated bath traditional Chinese medicine composition which is prepared from the following raw materials in parts by mass:
30-100 parts of melaleuca alternifolia, 10-25 parts of beefwood-like clubmoss herb, 1-15 parts of mulberry leaf, 1-15 parts of radix sophorae flavescentis, 3-20 parts of wormwood, 1-10 parts of radix stemonae and 1-25 parts of fructus kochiae.
Preferably, the medicated bath traditional Chinese medicine composition is prepared from the following raw materials in parts by mass:
70-90 parts of melaleuca alternifolia, 15-20 parts of beefwood-like clubmoss herb, 3-5 parts of mulberry leaf, 3-5 parts of sophora flavescens, 5-8 parts of wormwood, 2-4 parts of radix stemonae and 2-3 parts of fructus kochiae.
Preferably, the dosage form of the traditional Chinese medicine composition comprises external powder, effervescent tablets and external solution.
The invention also provides a preparation method of the medicated bath traditional Chinese medicine composition, which comprises the following steps: decocting the raw materials to obtain filtrate, namely the traditional Chinese medicine composition.
Preferably, the weight ratio of the total weight of the raw materials to the water in the decoction is 1 (3-10).
Preferably, the decocting times are 2 times, and the time of each decocting is 20-50 min.
Preferably, when the Chinese medicinal composition is an effervescent tablet, the preparation method further comprises: vacuum freeze-drying the filtrate to obtain powder, mixing the obtained powder with adjuvants, and tabletting to obtain effervescent tablet;
when the traditional Chinese medicine composition is external powder, the preparation method further comprises the following steps: and carrying out vacuum freeze drying on the filtrate to obtain the external powder of the traditional Chinese medicine composition.
Preferably, the auxiliary materials comprise one or more of citric acid, sodium bicarbonate, polyethylene glycol and polyvinylpyrrolidone.
The invention also provides application of the medicated bath traditional Chinese medicine composition or the medicated bath traditional Chinese medicine composition prepared by the preparation method in preparing a medicated bath agent for diminishing inflammation, relieving itching and relieving fatigue.
The invention provides a medicated bath traditional Chinese medicine composition which is prepared from the following raw materials in parts by mass: 30-100 parts of melaleuca alternifolia, 10-25 parts of beefwood-like clubmoss herb, 1-15 parts of mulberry leaf, 1-15 parts of radix sophorae flavescentis, 3-20 parts of wormwood, 1-10 parts of radix stemonae and 1-25 parts of fructus kochiae. The melaleuca alternifolia in the traditional Chinese medicine composition has the effects of diminishing inflammation, inhibiting bacteria, relieving itching, relieving pain, expelling parasites, preventing corrosion and the like, and is matched with traditional Chinese medicines such as fructus kochiae, radix stemonae and herba lycopodii which have the effects of killing parasites and relieving itching, and relaxing tendons and activating collaterals, so that the traditional Chinese medicine composition disclosed by the invention achieves the remarkable effects of relieving itching, relieving fatigue and improving sleep.
According to the embodiment, the medicated bath traditional Chinese medicine composition provided by the invention has the technical effects of improving sleep quality and treating skin itch.
Detailed Description
The invention provides a medicated bath traditional Chinese medicine composition which is prepared from the following raw materials in parts by mass: 30-100 parts of melaleuca alternifolia, 10-25 parts of beefwood-like clubmoss herb, 1-15 parts of mulberry leaf, 1-15 parts of radix sophorae flavescentis, 3-20 parts of wormwood, 1-10 parts of radix stemonae and 1-25 parts of fructus kochiae.
The preparation raw materials of the medicated bath traditional Chinese medicine composition comprise, by mass, 30-100 parts of melaleuca alternifolia, and preferably 70-90 parts.
Based on the mass parts of melaleuca alternifolia, the preparation raw materials of the medicated bath traditional Chinese medicine composition provided by the invention comprise 10-25 parts of beefwood-like clubmoss herb, preferably 15-20 parts.
The preparation raw materials of the medicated bath traditional Chinese medicine composition provided by the invention comprise 1-15 parts of mulberry leaves, preferably 3-5 parts of melaleuca alternifolia by mass.
The preparation raw materials of the medicated bath traditional Chinese medicine composition provided by the invention comprise 1-15 parts of radix sophorae flavescentis, preferably 3-5 parts of melaleuca alternifolia by mass.
The preparation raw materials of the medicated bath traditional Chinese medicine composition provided by the invention comprise 3-20 parts of wormwood, preferably 5-8 parts by mass based on the mass parts of melaleuca alternifolia.
The preparation raw materials of the medicated bath traditional Chinese medicine composition provided by the invention comprise 1-10 parts of radix stemonae, preferably 2-4 parts of radix stemonae, based on the mass parts of melaleuca alternifolia.
The preparation raw materials of the medicated bath traditional Chinese medicine composition provided by the invention comprise 1-25 parts of fructus kochiae, preferably 2-3 parts of melaleuca alternifolia by mass.
The melaleuca alternifolia and the wormwood in the invention have the efficacies of aromatizing, eliminating dampness, inhibiting bacteria and nourishing skin; the belvedere fruit and the stemona root have the effects of removing dampness, inhibiting bacteria, killing parasites and relieving itching; the beefwood-like clubmoss herb has the effects of relaxing tendons and activating collaterals; folium Mori has effects of dispelling pathogenic wind and heat, clearing lung-heat, moistening dryness, removing liver fire, and improving eyesight; radix Sophorae Flavescentis has effects of clearing heat, eliminating dampness, and killing parasite. The traditional Chinese medicine composition for medicated bath provided by the invention can also have the technical effects of killing parasites, relieving itching, eliminating fatigue, dispelling wind and heat, relaxing tendons, activating collaterals and improving the sub-health state of a human body. The medicated bath traditional Chinese medicine composition provided by the invention is prepared from natural traditional Chinese medicine raw materials, does not contain preservatives, and has no stimulation to the skin of a patient. The source of the traditional Chinese medicine raw materials is not particularly limited, and the traditional Chinese medicine is prepared by adopting conventional commercially available medicinal products.
The dosage form of the medicated bath traditional Chinese medicine composition provided by the invention preferably comprises external powder, effervescent tablets, external solution and the like.
The invention also provides a preparation method of the medicated bath traditional Chinese medicine composition, which comprises the following steps: decocting the raw materials to obtain filtrate, namely the traditional Chinese medicine composition.
The traditional Chinese medicine composition is obtained by decocting raw materials to obtain filtrate. In the invention, the decoction is divided into two times of decoction; the time of each decoction is preferably 20-50 min, more preferably 30min, the mass ratio of the raw materials to the water in each decoction is preferably 1 (3-10), more preferably the mass ratio of the raw materials to the water in the first decoction is 1:7, and the mass ratio of the raw materials to the water in the second decoction is 1: 5. The invention preferably combines the two times of decoction and filters the obtained filtrate to obtain the traditional Chinese medicine composition. The invention takes the filtrate as the external solution.
In the present invention, when the Chinese medicinal composition is used as an external powder, the preparation method preferably further comprises: the filtrate was freeze-dried in vacuo to obtain a powder. In the invention, the pressure of the vacuum freeze drying is preferably 1.5Pa to 10Pa, more preferably 2.3Pa, and the temperature is preferably-40 ℃ to-80 ℃, more preferably-65 ℃; after crushing, the powder is preferably sieved through a 100-mesh sieve. The powder is preferably filled into a bath bag, and the bath bag is preferably made of non-woven fabric, cotton cloth or soluble material. The invention furthest retains the original medicinal properties of the traditional Chinese medicine composition by carrying out vacuum freeze drying treatment on the filtrate.
In the present invention, when the Chinese medicinal composition is used as an effervescent tablet, the preparation method preferably comprises: vacuum freeze drying the filtrate to obtain powder, mixing the obtained powder with adjuvants, and tabletting to obtain effervescent tablet. In the present invention, the preparation method of the powder is the same as that of the external powder, and is not described herein again. In the present invention, the auxiliary material preferably includes one or more of citric acid, sodium bicarbonate, polyethylene glycol and polyvinylpyrrolidone; when the auxiliary materials are citric acid, sodium bicarbonate, polyethylene glycol and polyvinylpyrrolidone, the mass ratio of the powder to the citric acid, the sodium bicarbonate, the polyethylene glycol and the polyvinylpyrrolidone is preferably 43.5:25:25:4: 2.5. In the present invention, the molecular weight of polyethylene glycol is preferably 600. The present invention has no particular requirement on the manner of such mixed compression, as is well known to those skilled in the art.
The sources of the auxiliary materials are not particularly limited, and the auxiliary materials can be prepared from conventional commercial products.
The preparation method of the medicated bath traditional Chinese medicine composition pair provided by the invention is simple, the use is convenient, and the medicated bath traditional Chinese medicine composition pair is suitable for long-term use by patients.
The invention also provides application of the medicated bath traditional Chinese medicine composition or the medicated bath traditional Chinese medicine composition prepared by the preparation method in preparing a medicated bath agent for diminishing inflammation, relieving itching and relieving fatigue.
In the invention, the usage of the medicated bath traditional Chinese medicine composition is preferably as follows: putting 120-300 g of the medicated bath traditional Chinese medicine composition in the form of effervescent tablets, 120-300 g of a bath bag or 50-150 g of an external solution into 30-50L of water, and after the contents in the bath bag are completely dissolved or the effervescent tablets are completely dissolved in the water, carrying out whole-body immersion bath on a patient, wherein the bath water temperature is preferably 35-40 ℃.
In order to further illustrate the present invention, the following examples are provided to describe the medicated bath Chinese medicinal composition and its preparation and application in detail, but they should not be construed as limiting the scope of the present invention.
Example 1
Taking 70 parts of freshly-harvested melaleuca alternifolia and 15 parts of beefwood-like clubmoss herb, removing impurities, drying, crushing, and screening by a No. 4 sieve; taking 3 parts of newly harvested mulberry leaves and 5 parts of wormwood, removing impurities, and drying in the sun; taking 3 parts of radix sophorae flavescentis, 2 parts of radix stemonae and 2 parts of fructus kochiae, cleaning, drying, and cutting into 2-4 mm tablets.
Mixing the above materials, adding water 7 times the weight of the materials, soaking for 20min, decocting for 30min, filtering, and collecting filtrate; adding water 5 times the weight of the raw materials into the residues, decocting for 30min, filtering, and mixing the filtrates to obtain the Chinese medicinal composition.
Vacuum freeze drying the Chinese medicinal composition at 2.3Pa and 65 deg.C for 48 hr, pulverizing, and sieving with 100 mesh sieve to obtain powder.
Adding 25% of citric acid, 25% of sodium bicarbonate, 4% of PEG600, 2.5% of polyvinylpyrrolidone and the like into the powder according to the mass percentage of the powder, uniformly mixing, sieving by a 100-mesh sieve, and tabletting to obtain the medicated bath traditional Chinese medicine composition in the form of effervescent tablets.
The using method comprises the following steps: 120-300 g of the Chinese medicinal composition for medicated bath in the form of effervescent tablets is taken and placed in a bathtub or a bathtub, the water temperature is controlled to be between 35 and 40 ℃, and the patient can be soaked in the whole body after the effervescent tablets are dissolved.
Example 2
Taking 90 parts of freshly-collected melaleuca alternifolia and 20 parts of beefwood-like clubmoss herb, removing impurities, drying, crushing, and sieving with a 4-mesh sieve; taking 5 parts of newly harvested mulberry leaves and 8 parts of wormwood, removing impurities, and drying in the sun; taking 5 parts of radix sophorae flavescentis, 4 parts of radix stemonae and 3 parts of fructus kochiae, cleaning, drying and cutting into 2-4 mm tablets.
Mixing the above materials, adding water 7 times the weight of the materials, soaking for 20min, decocting for 30min, filtering, and collecting filtrate; adding water 5 times the weight of the raw materials into the residues, decocting for 30min, filtering, and mixing the filtrates to obtain the Chinese medicinal composition.
Vacuum freeze drying the Chinese medicinal composition at 2.3Pa and 65 deg.C for 48 hr, pulverizing, and sieving with 100 mesh sieve to obtain powder. Mixing the powders, and packaging into non-woven fabric/cotton cloth/soluble material bath bag containing powder of Chinese medicinal composition 120 g.
The using method comprises the following steps: placing a bath bag in a bathtub or bathtub, controlling the water temperature at 35-40 deg.C, and soaking the patient's body after the effervescent agent is dissolved.
Application example 1
40 subjects with skin itch and poor sleep quality within the age of 40-80 are selected, the effervescent tablets and the bath bags provided by the embodiment of the invention are used for respectively treating, bathing is carried out for 10-20 minutes every day, three weeks are a treatment course, and the physical conditions of the subjects are tracked after the three treatment courses are finished.
The therapeutic effect judgment standard for improving the sleep quality is as follows: the sleep quality is obviously improved; no obvious/no effect: the sleep quality was not significantly improved, with little or no change. The determination standard of the curative effect of skin itch is as follows: has the following effects: the pruritus is completely disappeared or obviously relieved; no obvious/no effect: the itching was not significantly improved, with no or no significant changes.
The statistical results are shown in table 1.
TABLE 1 statistics on the effect of subjects on improving sleep quality and skin itch
As can be seen from Table 1, the medicated bath traditional Chinese medicine composition with various dosage forms provided by the embodiment can improve the sleep quality of patients and effectively treat the problem of skin itch of the patients. And the use method is convenient and fast, and is convenient for market popularization.
Although the present invention has been described with reference to the preferred embodiments, it should be understood that various changes and modifications can be made therein by those skilled in the art without departing from the spirit and scope of the invention as defined in the appended claims.
Claims (9)
1. A medicated bath traditional Chinese medicine composition is prepared from the following raw materials in parts by mass:
30-100 parts of melaleuca alternifolia, 10-25 parts of beefwood-like clubmoss herb, 1-15 parts of mulberry leaf, 1-15 parts of radix sophorae flavescentis, 3-20 parts of wormwood, 1-10 parts of radix stemonae and 1-25 parts of fructus kochiae.
2. The medicated bath traditional Chinese medicine composition according to claim 1, which is prepared from the following raw materials in parts by mass:
70-90 parts of melaleuca alternifolia, 15-20 parts of beefwood-like clubmoss herb, 3-5 parts of mulberry leaf, 3-5 parts of sophora flavescens, 5-8 parts of wormwood, 2-4 parts of radix stemonae and 2-3 parts of fructus kochiae.
3. The medicated bath traditional Chinese medicine composition according to claim 1 or 2, wherein the dosage form of the traditional Chinese medicine composition comprises external powder, effervescent tablets and external solution.
4. The method for preparing a medicated bath traditional Chinese medicine composition according to any one of claims 1 to 3, which is characterized by comprising the following steps:
decocting the raw materials to obtain filtrate, namely the traditional Chinese medicine composition;
or
The raw materials are refluxed and extracted to obtain liquid medicine, namely the traditional Chinese medicine composition.
5. The preparation method according to claim 4, wherein the weight ratio of the total weight of the raw materials to water in the decoction is 1 (3-10).
6. The preparation method according to claim 4, wherein the number of the decoction is 2, and the time of each decoction is 20-50 min.
7. The method of claim 4, wherein when the Chinese medicinal composition is an effervescent tablet, the method further comprises: vacuum freeze-drying the filtrate to obtain powder, mixing the obtained powder with adjuvants, and tabletting to obtain effervescent tablet;
when the traditional Chinese medicine composition is external powder, the preparation method further comprises the following steps: and carrying out vacuum freeze drying on the filtrate to obtain the external powder of the traditional Chinese medicine composition.
8. The preparation method of claim 7, wherein the auxiliary materials comprise one or more of citric acid, sodium bicarbonate, polyethylene glycol and polyvinylpyrrolidone.
9. The application of the medicated bath traditional Chinese medicine composition as claimed in any one of claims 1 to 3 or the medicated bath traditional Chinese medicine composition prepared by the preparation method as claimed in any one of claims 4 to 8 in preparing anti-inflammation, itching-relieving and fatigue-relieving medicated bath agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010778324.3A CN111743873A (en) | 2020-08-05 | 2020-08-05 | Medicated bath traditional Chinese medicine composition and preparation and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010778324.3A CN111743873A (en) | 2020-08-05 | 2020-08-05 | Medicated bath traditional Chinese medicine composition and preparation and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111743873A true CN111743873A (en) | 2020-10-09 |
Family
ID=72712966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010778324.3A Pending CN111743873A (en) | 2020-08-05 | 2020-08-05 | Medicated bath traditional Chinese medicine composition and preparation and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111743873A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115192631A (en) * | 2022-08-29 | 2022-10-18 | 北京明阳华夏科技有限公司 | Preparation method of cinnamon extract, cinnamon extract and application of cinnamon extract |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660264A (en) * | 2004-12-20 | 2005-08-31 | 四川省今伟科技发展有限公司 | Combination of Chinese traditional for feet bath and preparation method |
| CN102920844A (en) * | 2012-11-19 | 2013-02-13 | 倪娜 | Medicament for prevention and adjunctive treatment of puerperal fever of puerpera |
| CN108379411A (en) * | 2018-05-15 | 2018-08-10 | 黄巧明 | The Chinese medicine bathing instant granular of improvement sleep quality and preparation and application method |
| CN110755533A (en) * | 2019-11-28 | 2020-02-07 | 北斗星量子生物医药科技(深圳)有限公司 | Traditional Chinese medicine solution for treating skin diseases and preparation method and application thereof |
-
2020
- 2020-08-05 CN CN202010778324.3A patent/CN111743873A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660264A (en) * | 2004-12-20 | 2005-08-31 | 四川省今伟科技发展有限公司 | Combination of Chinese traditional for feet bath and preparation method |
| CN102920844A (en) * | 2012-11-19 | 2013-02-13 | 倪娜 | Medicament for prevention and adjunctive treatment of puerperal fever of puerpera |
| CN108379411A (en) * | 2018-05-15 | 2018-08-10 | 黄巧明 | The Chinese medicine bathing instant granular of improvement sleep quality and preparation and application method |
| CN110755533A (en) * | 2019-11-28 | 2020-02-07 | 北斗星量子生物医药科技(深圳)有限公司 | Traditional Chinese medicine solution for treating skin diseases and preparation method and application thereof |
Non-Patent Citations (3)
| Title |
|---|
| 国家中医药管理局专业技术资格考试专家委员会: "《中医骨伤科学》", 31 March 2011, 中国中医药出版社 * |
| 肖国仕等: "《皮肤病诊疗手册》", 30 April 2019, 河南科学技术出版社 * |
| 葛静: "《学用药浴不生病随身查》", 31 July 2014, 天津科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115192631A (en) * | 2022-08-29 | 2022-10-18 | 北京明阳华夏科技有限公司 | Preparation method of cinnamon extract, cinnamon extract and application of cinnamon extract |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102091258B (en) | Chinese medicinal composition for dispelling scars and preparation method thereof | |
| CN103768567B (en) | A kind of black plaster and preparation method thereof | |
| CN103740558A (en) | Dendrobium nobile wine and preparation method thereof | |
| CN102166278B (en) | Chinese medicinal composition for treating pediatric rheumatoid arthritis and preparation method thereof | |
| CN102772704A (en) | Medicament for treating geriatric disease | |
| CN103316145B (en) | A kind of Traditional Chinese medicine foot soaping liquid and preparation method for the treatment of lower limb distending pain | |
| CN108379411A (en) | The Chinese medicine bathing instant granular of improvement sleep quality and preparation and application method | |
| CN111840405A (en) | Sleep-aiding foot patch and preparation method thereof | |
| CN111743873A (en) | Medicated bath traditional Chinese medicine composition and preparation and application thereof | |
| CN117959374A (en) | Preparation method and application of Chinese medicine health-care roasted smoked drink composition with both medicinal and edible properties | |
| CN104207567B (en) | A kind of multifunctional health-care medical pillow and making method thereof | |
| CN105709020A (en) | Foot bath powder with folium artemisiae argyi decoction dregs and preparation method thereof | |
| CN1205887A (en) | Pain relieving ointment | |
| CN1089854A (en) | Wet dressing quick-acting antidiarrheal medicine | |
| CN109674704A (en) | A kind of Chinese medicine bathing antibacterial liquid/particle improving damp-heat constitution and preparation and application method | |
| CN104547574A (en) | Traditional Chinese medicine for treating kidney deficiency | |
| CN109223866A (en) | A kind of wormwood powder for dipping feet and preparation method thereof | |
| CN109602851A (en) | A kind of Chinese medicine bathing antibacterial liquid/particle improving yin-deficiency constitution and preparation and application method | |
| CN105169034A (en) | Traditional Chinese medicine composition for treating hypertension and preparation method thereof | |
| CN110613767A (en) | Traditional Chinese medicine formula for treating amblyopia and application thereof | |
| CN104666799A (en) | Blood circulation activating and blood stasis removing medicinal liquor for soft tissue injury and preparation method of medicinal liqour | |
| CN104524397A (en) | Traditional Chinese medicine composition for assisted rehabilitation of stroke and preparation method of composition | |
| CN104069402B (en) | A kind of Chinese medicine composition and its preparation method and application of hair growth, white hair | |
| CN109924553A (en) | A kind of Chinese herbal medicine socks for preventing and treating tinea pedis | |
| CN109223972A (en) | A kind of Chinese medicine composition that treating prostate and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201009 |