CN110876708A - Composition for repairing damaged cells - Google Patents
Composition for repairing damaged cells Download PDFInfo
- Publication number
- CN110876708A CN110876708A CN201911161808.7A CN201911161808A CN110876708A CN 110876708 A CN110876708 A CN 110876708A CN 201911161808 A CN201911161808 A CN 201911161808A CN 110876708 A CN110876708 A CN 110876708A
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- composition
- damaged cells
- ophiopogonin
- bifidobacterium
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- 239000000203 mixture Substances 0.000 title claims abstract description 80
- 229930190017 ophiopogonin Natural products 0.000 claims abstract description 44
- 241000186000 Bifidobacterium Species 0.000 claims abstract description 42
- 229930182494 ginsenoside Natural products 0.000 claims description 21
- 229940089161 ginsenoside Drugs 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical group O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000008367 deionised water Substances 0.000 claims description 11
- 229910021641 deionized water Inorganic materials 0.000 claims description 11
- 239000002537 cosmetic Substances 0.000 claims description 8
- 235000008434 ginseng Nutrition 0.000 claims description 6
- 239000011159 matrix material Substances 0.000 claims description 6
- 240000004371 Panax ginseng Species 0.000 claims 1
- 235000002789 Panax ginseng Nutrition 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000037303 wrinkles Effects 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 5
- 208000003351 Melanosis Diseases 0.000 abstract description 4
- 230000002195 synergetic effect Effects 0.000 abstract description 4
- 206010014970 Ephelides Diseases 0.000 abstract description 3
- 230000036039 immunity Effects 0.000 abstract description 3
- 230000001815 facial effect Effects 0.000 abstract description 2
- 230000004060 metabolic process Effects 0.000 abstract description 2
- 230000001172 regenerating effect Effects 0.000 abstract description 2
- 238000002474 experimental method Methods 0.000 description 15
- 239000006071 cream Substances 0.000 description 10
- 230000001153 anti-wrinkle effect Effects 0.000 description 8
- 230000003020 moisturizing effect Effects 0.000 description 8
- 241000208340 Araliaceae Species 0.000 description 5
- 241000699666 Mus <mouse, genus> Species 0.000 description 5
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 5
- 235000003140 Panax quinquefolius Nutrition 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 238000004806 packaging method and process Methods 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 3
- 238000010298 pulverizing process Methods 0.000 description 3
- 230000032683 aging Effects 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 229940088710 antibiotic agent Drugs 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000032677 cell aging Effects 0.000 description 2
- 230000001413 cellular effect Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 238000011049 filling Methods 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 150000002338 glycosides Chemical class 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000000194 supercritical-fluid extraction Methods 0.000 description 2
- 241000186016 Bifidobacterium bifidum Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010048245 Yellow skin Diseases 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 210000004177 elastic tissue Anatomy 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a composition for repairing damaged cells, which comprises active components and a carrier, wherein the active components comprise bifidobacterium and ophiopogonin, and the weight percentage of the components in the composition is as follows: 1.5-2.8% of bifidobacterium; ophiopogonin 2.3-3.6%; the balance of carrier. The bifidobacteria and the ophiopogonin are compounded to generate a synergistic effect, and the repairing and improving degree reaches more than 20%; the panaxoside is compounded with the bifidobacterium and the ophiopogonin, so that the immunity of the organism can be enhanced, the damaged cells can be repaired more conveniently, and the repair improvement degree is as high as more than 90%. The composition for repairing damaged cells slows down the metabolism of free radicals on cell tissues, smoothes facial wrinkles, lightens dark eye circles and eliminates under-eye puffiness, and achieves the effects of nourishing, repairing, regenerating, removing wrinkles, freckles, removing yellow and dark spots.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a composition for repairing damaged cells.
Background
Aging is a problem to be faced by all organisms, cellular aging is a part of life, and the process is irreversible, but more and more research is being carried out to delay the aging process to be longer, and the most fundamental way to cure cellular aging is to repair cells. Only if the damaged cells are effectively treated in time, the young state is really maintained. At present, antibiotics or hormones are used for repairing cells in the market, if the antibiotics or hormones are used excessively, harm is caused to human bodies, and the repairing degree of the repairing cells is less than 10%.
Disclosure of Invention
In order to solve the technical problems, the invention provides a composition for repairing damaged cells, which comprises active components and a carrier, wherein the active components comprise bifidobacterium and ophiopogonin, and the weight percentage of each component in the composition is as follows:
1.5-2.8% of bifidobacterium;
ophiopogonin 2.3-3.6%;
the balance of carrier.
Preferably, the active components also comprise ginsenoside, and the weight percentage of each component in the composition is as follows:
1.5-2.8% of bifidobacterium;
ophiopogonin 2.3-3.6%;
ginsenoside 0.8-2.2%;
the balance of carrier.
The bifidobacterium, the ophiopogonin and the ginsenoside have synergistic effect, and the capability of repairing damaged cells is obviously improved.
Preferably, the ginsenoside is extracted from the stem of ginseng, which is more easily absorbed by the skin.
Preferably the carrier is deionized water or a cosmetic base. The composition for repairing damaged cells can be made into jelly-shaped transparent cream, essence water or flowing emulsion according to different cosmetic matrixes.
The invention has the beneficial effects that: the bifidobacterium and the ophiopogonin are compounded to generate a synergistic effect, so that damaged cells are repaired, and the repair improvement degree reaches more than 20% (when the bifidobacterium and the ophiopogonin are used alone, the repair improvement degree is 10% or less); after the ginsenoside, the bifidobacterium and the ophiopogonin are compounded, the three have synergistic effect to enhance the immunity of the organism, are more beneficial to repairing damaged cells, and the repairing improvement degree is up to more than 90 percent. The composition for repairing damaged cells promotes the formation of collagen elastic fibers, enhances the immunity of the organism, enhances the natural water-retaining barrier of the skin, enables the skin to be moisturized for a long time, provides nutrients and water for the skin, effectively prevents coagulation, slows down the metabolism of free radicals on cell tissues, provides nutrients for the deep layer of the skin, smoothes facial wrinkles, lightens dark eye circles, eliminates eye bags and edema, and achieves the effects of nourishing, repairing, regenerating, removing wrinkles, resisting wrinkles, removing freckles, removing yellow and darkening. Make the skin plump, firm and elastic.
Drawings
Fig. 1 is a schematic flow chart of a preparation process of the moisturizing and anti-wrinkle essence cream in embodiment 7 of the invention.
Detailed Description
The related bifidobacteria, ophiopogonin and ginsenoside are obtained by the following means:
bifidobacteria: activating strain, fermenting, centrifuging, lyophilizing, and pulverizing.
Ophiopogonin: pulverizing radix Ophiopogonis, defatting, and extracting by supercritical extraction. It can also be obtained commercially, such as ophiopogonin from the Tibet Hanlin chemical company Limited.
Ginsenoside: pulverizing Ginseng radix, defatting, and extracting with supercritical extraction to obtain ginsenoside. It can also be obtained from commercial sources, such as ginsenoside produced by the Tibet Hanlin chemical company Limited.
The degree of improvement in repair involved in the cell repair experiment was "the ratio of repaired cells (B/cell) (B × 100%/a) after repair of damaged cells (a/cell)".
The clinical test for removing wrinkles in eyes relates to the wrinkle removing improvement degree, namely the proportion of the area of removed wrinkles compared with the area of wrinkles in the eyes before treatment.
The improvement degree of spot removing related to clinical experiments of spot removing, yellow and dark removing is 'the proportion of the spot area removed compared with the area of skin spot before treatment'; the related yellow-removing improvement degree is the proportion of the whitened area compared with the area of yellow skin before treatment; the degree of darkening removal and improvement is the proportion of the area which is brightened compared with the area of the skin which is darkened before treatment.
Example 1
The composition for repairing damaged cells comprises the following components in percentage by weight:
1.8% of bifidobacterium; ophiopogonin 2.6%; and 95.6% of deionized water. The components are stirred uniformly to obtain the composition for repairing damaged cells.
The composition for repairing damaged cells is used for cell repair experiments, mice are used as receptors, the composition for repairing damaged cells is smeared on damaged parts once in the morning and at night, the damaged cells are repaired, the repair result is shown in table 1, and the repair improvement degree of the composition containing bifidobacterium and ophiopogonin reaches 20% or more after the composition is used for 28 days.
Clinical experiments of removing eye wrinkles by using the composition for repairing damaged cells are carried out, the composition is applied to an affected part once in the morning and at night to treat the eye wrinkles, the treatment results are shown in table 2, and the composition containing bifidobacterium and ophiopogonin can be obtained, wherein the wrinkle removal improvement degree is 18% or more after the composition is used for 90 days.
Clinical experiments of removing spots, yellow and dark are carried out by using the composition for repairing damaged cells, the composition is applied to the face once in the morning and at night for treatment, the treatment results are shown in table 3, and the composition containing the bifidobacterium and the ophiopogonin can be obtained after being used for 90 days, and the improvement degree of the spots, the yellow and the dark can reach 10% or more.
TABLE 1 results of cellular repair of Bifidobacterium and ophiopogonin
TABLE 2 wrinkle removal results with Bifidobacterium and ophiopogonin
TABLE 3 speckle removing, yellow removing, and dark removing effects of Bifidobacterium and ophiopogonin
Example 2
The composition for repairing damaged cells comprises the following components in percentage by weight:
1.8% of bifidobacterium; ophiopogonin 2.6%; 1.2 percent of ginsenoside; and 94.4 percent of deionized water. The components are stirred uniformly to obtain the composition for repairing damaged cells.
The composition for repairing damaged cells is used for cell repair experiments, mice are used as receptors, the composition for repairing damaged cells is smeared on damaged parts once in the morning and at night, the damaged cells are repaired, the repair result is shown in table 4, and the repair improvement degree of the composition containing bifidobacterium, ophiopogonin and ginsenoside reaches 90% or more after the composition is used for 28 days.
Clinical experiments of removing eye wrinkles by using the composition for repairing damaged cells are carried out, the composition is applied to an affected part once in the morning and at night, the eye wrinkles are treated, the treatment results are shown in table 5, and the wrinkle removing improvement degree of the composition containing bifidobacterium, ophiopogonin and panaxoside reaches 90% or more after the composition is used for 90 days.
Clinical experiments of removing freckles, yellow and dark are carried out by using the composition for repairing damaged cells, the composition is applied to the face once in the morning and at night for treatment, the treatment results are shown in table 6, and the composition containing bifidobacterium, ophiopogonin and ginseng stem glycoside can be obtained, the freckle removing improvement degree reaches 60% or more and the yellow and dark removing improvement degree reaches 90% or more after the composition is used for 90 days.
TABLE 4 results of cell repair of Bifidobacterium, ophiopogonin and ginseng Stem glycoside
TABLE 5 wrinkle-removing results of Bifidobacterium, ophiopogonin and panaxoside
TABLE 6 speckle removing, yellow removing, and dark removing effects of Bifidobacterium and ophiopogonin
Example 3
The composition for repairing damaged cells comprises the following components in percentage by weight:
1.5% of bifidobacterium; ophiopogonin 2.3%; and 96.2% of deionized water. The components are stirred uniformly to obtain the composition for repairing damaged cells.
The composition for repairing damaged cells is used for cell repair experiments, mice are used as receptors, the composition for repairing damaged cells is smeared on damaged parts once in the morning and at night, and the damaged cells are repaired, so that the composition containing the bifidobacteria and the ophiopogonin has the repair improvement degree of 20% or more after being used for 28 days.
Example 4
The composition for repairing damaged cells comprises the following components in percentage by weight:
2.8% of bifidobacterium; ophiopogonin 3.6%; and 93.6 percent of deionized water. The components are stirred uniformly to obtain the composition for repairing damaged cells.
The composition containing the bifidobacterium and the ophiopogonin can be obtained by using the composition for repairing the damaged cells to carry out cell repair experiments, taking a mouse as a receptor, smearing the composition for repairing the damaged cells on the damaged part once in the morning and at night, and repairing the damaged cells, wherein the repairing improvement degree of the composition containing the bifidobacterium and the ophiopogonin reaches 20% or more after the composition is used for 28 days.
Example 5
The composition for repairing damaged cells comprises the following components in percentage by weight:
1.5% of bifidobacterium; ophiopogonin 2.3%; ginsenoside 0.8%; and 95.4% of deionized water. The components are stirred uniformly to obtain the composition for repairing damaged cells.
The composition containing the bifidobacterium, the ophiopogonin and the ginseng stem glucoside has a repairing improvement degree of 90 percent or more after being used for 28 days.
Example 6
The composition for repairing damaged cells comprises the following components in percentage by weight:
2.8% of bifidobacterium; ophiopogonin 3.6%; 2.2 percent of ginsenoside; and 92.8% of deionized water. The components are stirred uniformly to obtain the composition for repairing damaged cells.
The composition for repairing damaged cells is used for cell repair experiments, mice are used as receptors, the composition for repairing damaged cells is smeared on damaged parts once in the morning and at night, and the damaged cells are repaired, so that the composition containing the bifidobacterium, the ophiopogonin and the ginsenoside has the repair improvement degree of 90% or more after being used for 28 days.
Example 7
A composition (moisturizing and anti-wrinkle essence cream) for repairing damaged cells comprises the following components in percentage by weight: 1.8% of bifidobacterium; ophiopogonin 2.6%; 1.2 percent of ginsenoside; and the cosmetic base is 94.4 percent. The cosmetic matrix comprises the following components in percentage by weight:
the process flow for preparing the moisturizing and anti-wrinkle essence cream is shown in figure 1 and comprises the following steps:
① mixing and stirring:
⑴ adding ophiopogonin, ginsenoside and cosmetic matrix into a reaction kettle, stirring at room temperature at 40 rpm for 15 min, and mixing.
⑵ adding Bacillus bifidus into the reaction kettle, stirring for 10 min, sequentially adding essence, antisepticising, stirring for 5 min, stopping the machine, detecting, discharging, inspecting, and packaging.
② and filling with a semi-automatic filling machine.
③ packaging, adopting semi-automatic packaging, performing outer packaging on the filled product, and simultaneously performing identification detection, wherein each bottle of the product is provided with an identification printed with a product trademark, a net content, an execution standard, a production license number, an enterprise trademark, a production address, main raw materials of the product and the like, the finished product is boxed and boxed, the boxed batch is subjected to finished product inspection by a technical quality department, and can be put in storage after being qualified, and if the finished product is unqualified, the finished product is destroyed.
The composition for repairing damaged cells can be made into jelly-shaped transparent cream, namely moisturizing and anti-wrinkle essence cream by adding the matrix, and can be made into essence water or flowing emulsion by adding other matrixes.
When the moisturizing and anti-wrinkle essence cream is used for cell repair experiments, a mouse is used as a receptor, the composition for repairing damaged cells is applied to the damaged part once in the morning and at night, the damaged cells are repaired, the repair result is shown in table 7, and the repair improvement degree of the moisturizing and anti-wrinkle essence cream reaches 80% or more after the moisturizing and anti-wrinkle essence cream is used for 28 days. The cosmetic matrix is added to prepare the finished product which can be sold on the market, and the finished product has the function of repairing damaged cells. On the other hand, the addition of the matrix reduces the concentration of the effective components, so the effect is slightly reduced.
Table 7 cell repair results using moisturizing anti-wrinkle essence cream
Comparative example 1 (not according to the invention)
The composition comprises the following components in percentage by weight:
1.8% of bifidobacterium; and 98.2 percent of deionized water. The components are stirred uniformly to obtain the composition.
When the composition for repairing damaged cells is used for cell repair experiments, the composition for repairing damaged cells is smeared on damaged parts once in the morning and at night by taking a mouse as a receptor, the damaged cells are repaired, the repair result is shown in table 8, and the repair improvement degree is 10% or less after 28 days of use.
TABLE 8 results of cellular repair of Bifidobacterium
Comparative example 2 (not according to the invention)
The composition comprises the following components in percentage by weight:
ophiopogonin 2.6%; 97.4 percent of deionized water. The components are stirred uniformly to obtain the composition.
When a cell repair experiment is carried out by using the composition for repairing damaged cells, the composition for repairing damaged cells is smeared on a damaged part once in the morning and at night by using a mouse as a receptor, the damaged cells are repaired, the repair result is shown in table 9, and the repair improvement degree is 10% or less after 28 days of use.
TABLE 9 cell repair results for ophiopogonin
COMPARATIVE EXAMPLE 3 (not in accordance with the invention)
The composition comprises the following components in percentage by weight:
1.2 percent of ginsenoside; and 98.8 percent of deionized water. The components are stirred uniformly to obtain the composition.
When a cell repair experiment is carried out by using the composition for repairing damaged cells, the composition for repairing damaged cells is smeared on a damaged part once in the morning and at night by using a mouse as a receptor, the damaged cells are repaired, the repair result is shown in table 10, and the repair improvement degree is below 10% after 28 days of use.
TABLE 10 cell repair results for ginsenosides
Claims (4)
1. A composition for repairing damaged cells comprising an active ingredient and a carrier, wherein: the active components of the composition comprise bifidobacterium and ophiopogonin, and the weight percentage of each component in the composition is as follows:
1.5-2.8% of bifidobacterium;
ophiopogonin 2.3-3.6%;
the balance of carrier.
2. The composition for repairing damaged cells of claim 1, wherein: the active components also comprise ginsenoside, and the weight percentage of each component in the composition is as follows:
1.5-2.8% of bifidobacterium;
ophiopogonin 2.3-3.6%;
ginsenoside 0.8-2.2%;
the balance of carrier.
3. The composition for repairing damaged cells of claim 2, wherein: the ginsenoside is extracted from the stem of Panax ginseng.
4. The composition for repairing damaged cells of claim 1, wherein: the carrier is deionized water or a cosmetic matrix.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911161808.7A CN110876708A (en) | 2019-11-25 | 2019-11-25 | Composition for repairing damaged cells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911161808.7A CN110876708A (en) | 2019-11-25 | 2019-11-25 | Composition for repairing damaged cells |
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| Publication Number | Publication Date |
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| CN110876708A true CN110876708A (en) | 2020-03-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201911161808.7A Pending CN110876708A (en) | 2019-11-25 | 2019-11-25 | Composition for repairing damaged cells |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102198075A (en) * | 2011-06-08 | 2011-09-28 | 浙江欧诗漫集团有限公司 | Pearl whitening essence |
| CN102755281A (en) * | 2012-07-13 | 2012-10-31 | 无锡紫昂生物科技有限公司 | Cosmetic containing microbial modulator |
| CN107789288A (en) * | 2017-12-24 | 2018-03-13 | 姚佑灿 | One kind convergence Firm elite |
| CN108836925A (en) * | 2018-07-16 | 2018-11-20 | 广州市科能化妆品科研有限公司 | It is a kind of to resist the composition for doing quick Chinese medical extract and preparation method and the application in cosmetics |
| CN110037981A (en) * | 2019-06-06 | 2019-07-23 | 大连樱凝科技有限公司 | A kind of skin care item and the preparation method and application thereof |
-
2019
- 2019-11-25 CN CN201911161808.7A patent/CN110876708A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102198075A (en) * | 2011-06-08 | 2011-09-28 | 浙江欧诗漫集团有限公司 | Pearl whitening essence |
| CN102755281A (en) * | 2012-07-13 | 2012-10-31 | 无锡紫昂生物科技有限公司 | Cosmetic containing microbial modulator |
| CN107789288A (en) * | 2017-12-24 | 2018-03-13 | 姚佑灿 | One kind convergence Firm elite |
| CN108836925A (en) * | 2018-07-16 | 2018-11-20 | 广州市科能化妆品科研有限公司 | It is a kind of to resist the composition for doing quick Chinese medical extract and preparation method and the application in cosmetics |
| CN110037981A (en) * | 2019-06-06 | 2019-07-23 | 大连樱凝科技有限公司 | A kind of skin care item and the preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 中国香料香精化妆品工业协会: "《化妆品原料规格实用手册》", 31 December 2002 * |
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Application publication date: 20200313 |
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