CN110833615A - A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method - Google Patents
A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method Download PDFInfo
- Publication number
- CN110833615A CN110833615A CN201911319985.3A CN201911319985A CN110833615A CN 110833615 A CN110833615 A CN 110833615A CN 201911319985 A CN201911319985 A CN 201911319985A CN 110833615 A CN110833615 A CN 110833615A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- chinese medicine
- medicine composition
- chronic rhinitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 41
- 206010039083 rhinitis Diseases 0.000 title claims abstract description 38
- 201000009151 chronic rhinitis Diseases 0.000 title claims abstract description 31
- 238000002560 therapeutic procedure Methods 0.000 title claims abstract description 24
- 238000002360 preparation method Methods 0.000 title claims abstract description 19
- 239000000843 powder Substances 0.000 claims abstract description 85
- 239000003814 drug Substances 0.000 claims abstract description 83
- 241000213006 Angelica dahurica Species 0.000 claims abstract description 27
- 241000951473 Schizonepeta Species 0.000 claims abstract description 26
- 235000007516 Chrysanthemum Nutrition 0.000 claims abstract description 25
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 25
- 241000218378 Magnolia Species 0.000 claims abstract description 24
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 24
- 235000008397 ginger Nutrition 0.000 claims abstract description 24
- 244000291564 Allium cepa Species 0.000 claims abstract description 23
- 235000006679 Mentha X verticillata Nutrition 0.000 claims abstract description 23
- 235000002899 Mentha suaveolens Nutrition 0.000 claims abstract description 23
- 235000001636 Mentha x rotundifolia Nutrition 0.000 claims abstract description 23
- 241001180876 Saposhnikovia Species 0.000 claims abstract description 23
- 235000002732 Allium cepa var. cepa Nutrition 0.000 claims abstract description 22
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims abstract 3
- 244000067505 Xanthium strumarium Species 0.000 claims abstract 3
- 244000273928 Zingiber officinale Species 0.000 claims abstract 3
- 241000628997 Flos Species 0.000 claims description 24
- 238000002156 mixing Methods 0.000 claims description 21
- 238000001035 drying Methods 0.000 claims description 20
- 239000009670 cang er zi wan Substances 0.000 claims description 15
- 238000000605 extraction Methods 0.000 claims description 10
- 239000012467 final product Substances 0.000 claims description 10
- 239000003973 paint Substances 0.000 claims description 10
- 238000010298 pulverizing process Methods 0.000 claims description 10
- 238000007873 sieving Methods 0.000 claims description 10
- 238000005303 weighing Methods 0.000 claims description 10
- 230000000694 effects Effects 0.000 abstract description 49
- 210000004072 lung Anatomy 0.000 abstract description 20
- 206010019233 Headaches Diseases 0.000 abstract description 13
- 206010028748 Nasal obstruction Diseases 0.000 abstract description 13
- 231100000869 headache Toxicity 0.000 abstract description 13
- 206010039101 Rhinorrhoea Diseases 0.000 abstract description 12
- 208000024891 symptom Diseases 0.000 abstract description 10
- 208000010753 nasal discharge Diseases 0.000 abstract description 8
- 208000000059 Dyspnea Diseases 0.000 abstract description 6
- 206010013975 Dyspnoeas Diseases 0.000 abstract description 6
- 208000002173 dizziness Diseases 0.000 abstract description 5
- 230000002045 lasting effect Effects 0.000 abstract description 3
- 241000723353 Chrysanthemum Species 0.000 description 22
- 241001506766 Xanthium Species 0.000 description 22
- 241000234314 Zingiber Species 0.000 description 21
- 229940079593 drug Drugs 0.000 description 19
- 208000002193 Pain Diseases 0.000 description 10
- 230000006870 function Effects 0.000 description 10
- 230000036407 pain Effects 0.000 description 10
- 208000011580 syndromic disease Diseases 0.000 description 10
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 6
- 230000007812 deficiency Effects 0.000 description 6
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000001737 promoting effect Effects 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 4
- 241000699670 Mus sp. Species 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 4
- 208000036071 Rhinorrhea Diseases 0.000 description 4
- 230000009471 action Effects 0.000 description 4
- 230000000857 drug effect Effects 0.000 description 4
- 239000000284 extract Substances 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 230000004054 inflammatory process Effects 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- 239000006187 pill Substances 0.000 description 4
- 210000001944 turbinate Anatomy 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 241000283973 Oryctolagus cuniculus Species 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 230000004438 eyesight Effects 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 210000002850 nasal mucosa Anatomy 0.000 description 3
- 210000001331 nose Anatomy 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- 235000019640 taste Nutrition 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 210000001835 viscera Anatomy 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- UJBOOUHRTQVGRU-UHFFFAOYSA-N 3-methylcyclohexan-1-one Chemical compound CC1CCCC(=O)C1 UJBOOUHRTQVGRU-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 2
- 241000125175 Angelica Species 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 208000017667 Chronic Disease Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 241000721047 Danaus plexippus Species 0.000 description 2
- 235000001287 Guettarda speciosa Nutrition 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 206010061876 Obstruction Diseases 0.000 description 2
- 206010039085 Rhinitis allergic Diseases 0.000 description 2
- 206010053459 Secretion discharge Diseases 0.000 description 2
- 201000010105 allergic rhinitis Diseases 0.000 description 2
- 230000037005 anaesthesia Effects 0.000 description 2
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 208000027744 congestion Diseases 0.000 description 2
- 210000003128 head Anatomy 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 239000002398 materia medica Substances 0.000 description 2
- 201000009240 nasopharyngitis Diseases 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000001034 respiratory center Anatomy 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 206010041232 sneezing Diseases 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 239000007929 subcutaneous injection Substances 0.000 description 2
- 238000010254 subcutaneous injection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 210000004876 tela submucosa Anatomy 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- NFLGAXVYCFJBMK-DTWKUNHWSA-N (+)-menthone Chemical compound CC(C)[C@H]1CC[C@H](C)CC1=O NFLGAXVYCFJBMK-DTWKUNHWSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 241000758794 Asarum Species 0.000 description 1
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- IUCNQFHEWLYECJ-FNAJZLPOSA-L Atractyloside Chemical compound [K+].[K+].O1[C@H](CO)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OC(=O)CC(C)C)[C@@H]1O[C@H]1C[C@@]2(C)[C@@H]3CC[C@@H](C(=C)[C@@H]4O)C[C@]34CC[C@@H]2[C@H](C(O)=O)C1 IUCNQFHEWLYECJ-FNAJZLPOSA-L 0.000 description 1
- 206010006002 Bone pain Diseases 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 206010015958 Eye pain Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000229179 Ledebouriella Species 0.000 description 1
- 240000005378 Magnolia kobus Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241001480037 Microsporum Species 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 208000000112 Myalgia Diseases 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000005141 Otitis Diseases 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 241000223229 Trichophyton rubrum Species 0.000 description 1
- 241001480046 Trichophyton schoenleinii Species 0.000 description 1
- GLNADSQYFUSGOU-GPTZEZBUSA-J Trypan blue Chemical compound [Na+].[Na+].[Na+].[Na+].C1=C(S([O-])(=O)=O)C=C2C=C(S([O-])(=O)=O)C(/N=N/C3=CC=C(C=C3C)C=3C=C(C(=CC=3)\N=N\C=3C(=CC4=CC(=CC(N)=C4C=3O)S([O-])(=O)=O)S([O-])(=O)=O)C)=C(O)C2=C1N GLNADSQYFUSGOU-GPTZEZBUSA-J 0.000 description 1
- 208000037386 Typhoid Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 241001251949 Xanthium sibiricum Species 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 230000036982 action potential Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000013572 airborne allergen Substances 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000003444 anaesthetic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- FYQXODZRNSCOTR-UHFFFAOYSA-N atractyloside Natural products O1C(CO)C(OS(O)(=O)=O)C(OS(O)(=O)=O)C(OC(=O)CC(C)C)C1OC1CC2(C)C3CCC(C(=C)C4O)CC34CCC2C(C(O)=O)C1 FYQXODZRNSCOTR-UHFFFAOYSA-N 0.000 description 1
- 230000002457 bidirectional effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 229930004069 diterpene Natural products 0.000 description 1
- 150000004141 diterpene derivatives Chemical class 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 239000012259 ether extract Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000005089 fruit drop Effects 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 150000001261 hydroxy acids Chemical class 0.000 description 1
- 230000035874 hyperreactivity Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 238000010409 ironing Methods 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 235000014571 nuts Nutrition 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 235000014102 seafood Nutrition 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- HTSABYAWKQAHBT-UHFFFAOYSA-N trans 3-methylcyclohexanol Natural products CC1CCCC(O)C1 HTSABYAWKQAHBT-UHFFFAOYSA-N 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- 230000001515 vagal effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 210000002268 wool Anatomy 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy, which comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk. The invention also discloses a preparation process of the traditional Chinese medicine composition for treating chronic rhinitis by using the navel therapy. The medicament of the invention is powder which can be directly used for umbilical administration, is convenient for clinical application, convenient for carrying and low in cost, has the effects of dispelling wind and cold, freeing lung and dredging orifices, can effectively improve the clinical symptoms of nasal obstruction, dyspnea, sneeze, watery nasal discharge, headache, dizziness and the like of chronic rhinitis patients, has obvious clinical treatment effect and lasting curative effect, and has the total effective rate of more than 90 percent through comparison and observation of clinical treatment effect.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy and a preparation process thereof.
Background
Along with the change of living conditions and living environment of people, the prevalence of electric fans and air conditioners in chronic rhinitis tends to increase year by year. Rhinitis is a chronic disease of nasal mucosa and submucosa chronic congestion and swelling, turbinate hypertrophy of turbinates, filamentous secretion discharge in nasal passages, nasal obstruction, sticky nasal discharge, sneeze, heavy nasal sound and headache. Clinically, most chronic rhinitis patients are allergic to common airborne allergens (mites, pollen, pets, molds and the like), certain foods (nuts, milk, peanuts, seafood and the like) and medicines. The disease course is long and lingering, and the disease is not easy to be cured completely in clinic, thereby seriously affecting the life quality of people.
At present, for chronic rhinitis patients, the main treatment mode of western medicine is symptomatic treatment, hormone medicine treatment is most commonly used in the western medicine treatment means, the treatment aims to mainly inhibit inflammatory reaction of nasal mucosa and reduce nasal hyperreactivity, diseases cannot be eradicated fundamentally, clinical symptoms can be improved, and toxic and side effects are easily caused to the patients by long-term application of the hormone medicine.
Rhinitis is a chronic disease of nasal mucosa and submucosa chronic congestion and swelling, turbinate hypertrophy of turbinates, filamentous secretion discharge in nasal passages, nasal obstruction, sticky nasal discharge, sneeze, heavy nasal sound and headache. The chronic rhinitis belongs to the category of allergic rhinitis in the traditional Chinese medicine, and common reasons comprise cold attacking lung, cold evil lodging lung, deficiency and cold of lung qi and lung qi obstruction. It is often seen in the elderly, women, children, and people with common cold. Clinically, western medicine hormone treatment usually takes effect at that time, and after the treatment is stopped, nasal obstruction, rhinorrhea and sneezing appear, and symptoms are repeated; the traditional Chinese medicine preparation has better effect on treating rhinitis, but needs to be taken for a long time, so that a patient can not insist on the rhinitis for a long time and has certain side effect. The traditional Chinese medicine navel therapy is a traditional natural therapy, has the advantages of remarkable curative effect, quick response, safety, reliability, few side effects and the like, and has unique characteristics in clinical application. The main causes are lung qi deficiency, weak defensive exterior, wind-cold attacking the nasal orifice due to deficiency, the pathogenic factors fighting positively, lung qi failing to regulate, body fluid stopping and accumulating, nasal orifice obstruction, sneezing and snivel due to the cold, spleen qi failing to distribute to the lung due to spleen deficiency, lung qi failing to be rooted in the kidney, kidney deficiency failing to control and take up, qi failing to return to original qi, wind evil invading the interior. Therefore, allergic rhinitis is diseased in the lung, but its pathological changes have a certain relationship with the spleen and kidney. In clinical manifestations, the physician needs to relieve nasal obstruction, strengthen healthy qi to eliminate pathogens, tonify lung qi and strengthen the exterior, with the syndrome of deficiency and excess complicated with each other.
In clinical reports of treating chronic rhinitis by using Chinese patent medicines, the Chinese patent medicines show that the treatment course is short, the effect is quick, the curative effect is safe and reliable, and the Chinese patent medicines have the effect of treating both principal and secondary aspects of disease. However, most of the existing Chinese patent medicines are decoction during treatment and the components of the prescription are complex, so the traditional Chinese patent medicines are not convenient for patients in clinical use, and the volatilization of effective components caused by improper decoction methods during decoction often causes the reduction of drug effect.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating chronic rhinitis by using navel therapy and a preparation process thereof, and aims to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy is characterized in that: the paint comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
The composition preferably comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
Preferably, the Chinese medicinal composition is powder.
Preferably, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: sun drying radix Angelicae Dahuricae, flos Magnoliae, fructus Xanthii, herba Schizonepetae, radix Saposhnikoviae, rhizoma Zingiberis recens, herba Menthae, flos Chrysanthemi and Bulbus Allii Fistulosi respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Compared with the prior art, the medicament is powder, can be directly applied to umbilical region administration, is convenient for clinical application, convenient to carry and low in cost, has the effects of dispelling wind and cold, dispersing lung qi and dredging orifices, can effectively improve the clinical symptoms of nasal obstruction, dyspnea, sneeze, watery nasal discharge, headache, dizziness and the like of chronic rhinitis patients, has obvious clinical treatment effect and lasting curative effect, and has the total effective rate of over 90 percent through comparison and observation of the clinical treatment effect.
Detailed Description
The invention is further illustrated by the following examples, without limiting the scope of the invention.
Example 1
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 30g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 2
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 90g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 3
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 30g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 4
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 150g, flos Magnoliae 150g, fructus Xanthii 150g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 90g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 5
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 30g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 6
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 90g, radix Saposhnikoviae 90g, rhizoma Zingiberis recens 90g, herba Menthae 90g, flos Chrysanthemi 90g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 7
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 30g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 30g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Example 8
The invention provides a technical scheme, and a traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
In the embodiment, the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
In the embodiment, the traditional Chinese medicine composition is powder.
In the embodiment, the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: drying radix Angelicae Dahuricae 450g, flos Magnoliae 450g, fructus Xanthii 450g, herba Schizonepetae 270g, radix Saposhnikoviae 270g, rhizoma Zingiberis recens 90g, herba Menthae 270g, flos Chrysanthemi 270g, and Bulbus Allii Fistulosi 90g in the sun respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Examples of the experiments
The drugs prepared in the above examples 1 to 8 were tested with the cocklebur fruit drop pills for treating rhinitis (manufactured by Sichuan Herun pharmaceutical Co., Ltd.) in an efficient manner, and the results are shown in Table 1. In order to show the treatment effect of the medicine on chronic rhinitis, 100 chronic rhinitis patients are selected in total and observed in clinical treatment effect, and the age is 21-67 years old. The groups were randomly divided into 9 groups. Of these, 8 groups were the example group, and one group was the control group. The medicine is applied to the embodiment group, 1-3g of proper amount of powder is taken each time, the powder is blended into a soft paste by boiling water, the soft paste is filled on the umbilical region of a patient, moxibustion is carried out by a moxa column, 1 time is taken every day, the time is 60min-120min each time, and the medicine is fixed on the umbilical region for 6-8 hours by an adhesive tape after the moxibustion is finished; fructus Xanthii dripping pill (produced by Sichuan Herun pharmaceutical Co., Ltd.) for treating rhinitis in control group has 28 pills each time, and 3 times a day. Each group took 2 weeks as a course of treatment.
The clinical curative effect standard of the chronic rhinitis is as follows:
the effect is shown: the main symptoms of nasal obstruction, rhinorrhea, dyspnea and sneeze are slightly better, the symptoms recover more than 30% before treatment, and headache and dizziness are obviously changed;
the method has the following advantages: the main symptoms of nasal obstruction, rhinorrhea, dyspnea, sneeze and the like recover more than 60 percent than before treatment, and the headache disappears;
improvement: nasal obstruction, rhinorrhea, dyspnea, sneeze, headache and dizziness disappear;
and (4) invalidation: the patient had no significant reduction or worsening of the underlying symptoms.
The total effective rate is (significant effect + effective + improvement)/the total number of people is multiplied by 100%.
TABLE 1 comparison of clinical treatment effects of examples 1-8 and fructus Xanthii dripping pill for treating rhinitis
The total efficiency of the invention is: (285+131+351)/800 × 100 ═ 95.875%.
The angelica dahurica in the medicine has pungent and slightly bitter taste, warm nature and fragrant smell, governs hand-foot yangming, ascends the head and face, and has the effects of relieving exterior syndrome and dispelling cold, dispelling wind and relieving pain, dredging nasal orifices, eliminating dampness and stopping leukorrhagia, reducing swelling and expelling pus, and dispelling wind and relieving itching. Flos Magnoliae is pungent in flavor and warm in nature, and has the functions of expelling wind and cold, dredging the orifice, warming and dredging the channels, ascending clear and improving eyesight, and dispelling wind and heat, and can help clear yang and ascend the head and brain. The cocklebur fruit is pungent and bitter in taste and warm in nature, has the effects of dispelling wind-cold, freeing nasal orifices, eliminating dampness and relieving pain, and has the effects of freeing the brain top and externally reaching the skin, and the three medicines are monarch medicines together and have the effects of dispelling wind and cold, freeing lung and freeing orifices and relieving pain. Schizonepeta, herba Schizonepetae is pungent, slightly bitter, slightly warm in nature, and has the effects of dispelling pathogenic wind and relieving exterior syndrome; promoting eruption; the action of stopping bleeding. Fang Feng is pungent and sweet in flavor and warm in nature. Has effects in relieving exterior syndrome, inducing perspiration, dispelling pathogenic wind, and removing dampness. The ginger is pungent in flavor and slightly warm in nature, has the functions of sweating and relieving exterior syndrome, warming middle energizer and arresting vomiting, warming lung and relieving cough, and relieving fish and crab toxicity and drug toxicity, and is used as a ministerial drug for enhancing the functions of expelling wind and removing cold, ventilating lung and relieving exterior syndrome and easing nasal obstruction. The mint is cool in nature and pungent in taste, has the functions of clearing lung and soothing liver, and clearing heat and promoting eyesight, and the chrysanthemum is sweet and bitter in taste and slightly cold in nature, and has the effects of dispelling wind and heat, calming liver yang, clearing liver and improving eyesight, and clearing heat and removing toxicity. The two herbs are used together as adjuvant drugs to clear bitter and cold and descend to harmonize the actions of the drugs and inhibit the dryness of the drugs. The scallion stalk is pungent in flavor and warm in nature, has the functions of invigorating yang and promoting qi circulation, and is used as a guiding drug for ascending and descending the clear and turbid, dispersing wind-cold and relieving lung orifice pain with brain fluid self-consolidating .
Modern pharmacological research shows that the angelica has the effects of relieving fever, easing pain, resisting inflammation and exciting the center, and the angelica toxin can excite the brain-extending respiratory center, the blood vessel movement center, the vagal center and the spinal cord in a small amount to excite the respiration: 15g (crude drug)/kg of angelica dahurica decoction is used for intragastric administration, the heat clearing effect is obvious on the rabbits with fever caused by subcutaneous injection of peptone on the back, the effect is superior to 0.1g/kg of aspirin, the inhibition rates of the acetic acid writhing reaction of mice are 69.6%, 52.86% and 40.53% respectively when the angelica dahurica decoction, the ether extract and the water extract are used for intragastric administration, and the inhibition rates of the acetic acid writhing reaction of the mice are respectively 69.6%; the compound preparation has an obvious inhibiting effect on ear inflammation of mice with xylene, can improve the in-vivo hypersensitive state of allergic disease patients, improves microcirculation by enhancing the immunity of organisms, and has the effects of relieving fever, easing pain and resisting inflammation; flos Magnoliae has inhibitory effect on various pathogenic fungi, and 15-30% flos Magnoliae decoction or infusion has local anesthetic effect on animals (infiltration anesthesia on guinea pig and interdiction anesthesia on frog). The Japanese magnolia flower M.kobus has obvious antiviral effect on the gonococcal choriomeningitis virus in vitro and in vivo (the mice are injected with the decoction subcutaneously). Fructus Xanthii has antiinflammatory effect, and diterpene hydroxy acid atractyloside contained in the product has antiinflammatory effect as shown by rat carrageenin edema test. The LD50 for intraperitoneal injection, subcutaneous injection and oral administration is 2.9, 5.3 and 350mg/kg respectively. The cocklebur fruit decoction has certain bacteriostasis to staphylococcus aureus in vitro, and the acetone or ethanol extract thereof also has bacteriostasis to trichophyton rubrum in vitro. Fructus Xanthii 100% decoction 0.3 ml/mouse has effect of relieving cough; 15ml/kg has no phlegm eliminating effect on rabbit, and the tincture has breath exciting effect on frog. The schizonepeta has the effects of relieving fever and easing pain: the typhoid mixed vaccine is used for heating the rabbits, and schizonepeta decoction or ethanol infusion is administered at 2g/kg for intragastric administration, so that the febrifuge mixed vaccine only has weak antipyretic effect. The herba Schizonepetae decoction has antipyretic and analgesic effects. D-menthone in the schizonepeta is a main analgesic component, and 3-methylcyclohexanone also has an analgesic effect. The divaricate saposhnikovia root has a bidirectional regulation effect, can sweat and stop sweating, can stop diarrhea, relax bowels, stop bleeding and dredge channels, so the application in clinic is relatively wide; the herba Menthae contains menthol, and the substance has effects of refreshing breath, relieving abdominal pain and cholecystspasm, resisting corrosion, killing bacteria, promoting urination, eliminating phlegm, invigorating stomach, promoting digestion, etc., and can be used for treating headache and myalgia. The ginger alcohol extract has an exciting effect on the blood vessel movement center and the respiratory center of the anesthetized cat. The chrysanthemum extract is injected into abdominal cavity of mouse, so that the diffusion of local trypan blue injected into intradermal tissue amine is small, the capillary resistance can be enhanced, and the chrysanthemum extract can inhibit the permeability of capillary and has anti-inflammatory effect. The Bulbus Allii Fistulosi has effect in inhibiting Shigella shigella in vitro, and the water infusion is diluted with test tube at a ratio of 1:10 to inhibit Trichophyton schoenleinii and Microsporum ozoloides, and has antibacterial and antifungal effects.
The navel-applying therapy with traditional Chinese medicine refers to an external treatment method for preventing and treating diseases by applying traditional Chinese medicine on the navel (Shenque acupoint) and combining moxibustion or hot ironing under the guidance of holistic concept and treatment principle of syndrome differentiation, so that the medicine stimulates qi of meridians and collaterals, dredges qi and blood, and regulates viscera by virtue of the force of moxibustion and the nature of moxibustion. Modern researches find that drug molecules and all physical molecules easily penetrate through the horny layer of the umbilical skin, enter intercellular substance and rapidly diffuse into blood to reach the whole body; meanwhile, the medicine can quickly form physical vapor pressure under body temperature or other heat sources, so that action potentials of tissue cells can be converted into nerve impulses, and the self-regulation function of the organism is mobilized through the reflection of the internal organs of the body, thereby achieving the purposes of regulating the functions of the internal organs, balancing yin and yang, strengthening the body resistance and eliminating evil.
The invention adopts angelica dahurica, biond magnolia flower, siberian cocklour fruit, fineleaf schizonepeta herb, divaricate saposhnikovia root, ginger, mint, fistular onion stalk and chrysanthemum to form the traditional Chinese medicine navel therapy prescription, and the angelica dahurica has the effects of dispelling cold and relieving exterior syndrome: dispelling pathogenic wind and relieving pain, and dredging nasal orifice, and can be used for treating common cold and wind cold, headache, nasal obstruction, migraine, supra-orbital bone pain, nasal discharge, and smellless odor, and is often combined with rhizoma Ligustici Chuanxiong, flos Magnoliae, fructus Xanthii, and radix Saposhnikoviae, and is described in compendium of materia Medica: for nasosinusitis, epistaxis, toothache and supra-orbital pain, the magnolia flower has the functions of dispelling wind-cold and relieving stuffy nose, and is used for wind-cold headache, nasal obstruction, nasosinusitis and thick nasal discharge, and it enters lung meridian and passes through nose to dispel wind-cold for treating thick nasal discharge, smelling neither smell nor odor, nasosinusitis and other symptoms in Chinese pharmacopoeia, and is often combined with dahurian angelica root, asarum herb, ledebouriella root, cocklebur fruit and the like. Xanthium sibiricum (materia Medica Mongolian fish pot): "Zhi headache and Shu Tong Tomen, Zhu Feng Du ren in marrow", has the actions of dispersing wind and alleviating pain, dispelling dampness and killing parasites. It is good at treating headache due to wind-cold, nasosinusitis and toothache. The three ingredients are used as monarch drugs to enhance the functions of relieving exterior syndrome, dispelling cold, ventilating lung, dredging orifices, dispelling wind and relieving pain. The clinical test results show that: the traditional Chinese medicine for treating chronic rhinitis by using the navel therapy has good curative effect, statistical difference (P is less than 0.05) exists between two groups, and the traditional Chinese medicine is simple, convenient and easy to implement, has no toxic or side effect, and is easy to accept by patients.
The traditional Chinese medicine raw materials with the mixture ratio integrate the drug effects of the traditional Chinese medicines, and are reasonably matched to enable the drug effects to be more thoroughly exerted, and meanwhile, the situation of drug effect offset among the traditional Chinese medicines is avoided. The medicine of the invention is researched by combining modern pharmacological action and modern pharmacodynamics, so that the medicines of the invention have the functions of enhancing immunologic function, resisting inflammation and inhibiting bacteria after being reasonably matched. And the selected raw materials of various Chinese patent medicines have low cost, are suitable for large-scale production and are convenient for more patients to use clinically.
The specific use method of the medicine comprises the following steps: the application method comprises mixing 1-3g of the powder with boiling water, making into soft paste, applying to umbilical region of patient, performing warm moxibustion with moxa stick or moxa wool, and fixing the medicine on umbilical region with adhesive plaster for 6-8 hr.
In conclusion, the medicament and the preparation method thereof provided by the invention fully exert the medicinal effects of various components, and the medicament finally prepared into the navel can be used for direct administration on the navel, is more favorable for remarkable absorption effect, has quick response time, is convenient for clinical application, is convenient to carry, has low cost, has the effects of dispersing lung qi, relieving exterior syndrome, dispelling wind and cold, relieving stuffy nose, strengthening body resistance and eliminating evil, can effectively improve the clinical symptoms of nasal obstruction, dyspnea, sneeze, watery nasal discharge, headache, dizziness and the like of patients with chronic rhinitis, has remarkable clinical treatment effect and lasting curative effect, and has the total effective rate of over 90 percent through comparison and observation of clinical effects.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein, and any reference thereto is therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (4)
1. A traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy is characterized by comprising the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of biond magnolia flower, 5-15 parts of cocklebur fruit, 3-9 parts of schizonepeta, 3-9 parts of divaricate saposhnikovia root, 1-3 parts of ginger, 3-9 parts of mint, 3-9 parts of chrysanthemum and 1-3 parts of fistular onion stalk.
2. The traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy according to claim 1, which is characterized in that: the paint comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 5 parts of cocklebur fruit, 3 parts of fineleaf schizonepeta herb, 3 parts of divaricate saposhnikovia root, 1 part of ginger, 3 parts of mint, 3 parts of chrysanthemum and 1 part of fistular onion stalk.
3. The traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy according to claim 1, which is characterized in that: the traditional Chinese medicine composition is powder.
4. The traditional Chinese medicine composition for treating chronic rhinitis by umbilical therapy according to claim 1, which is characterized in that: the preparation process of the traditional Chinese medicine composition comprises the following steps:
a: sun drying radix Angelicae Dahuricae, flos Magnoliae, fructus Xanthii, herba Schizonepetae, radix Saposhnikoviae, rhizoma Zingiberis recens, herba Menthae, flos Chrysanthemi and Bulbus Allii Fistulosi respectively;
b: weighing the components in the step a according to the formula amount, mixing and pulverizing to obtain coarse powder for later use;
c: b, sieving the coarse powder obtained in the step b by using a 200-mesh fine sieve for extraction, and obtaining fine powder for later use;
d: c, drying the fine powder obtained in the step c to obtain dry fine powder for later use;
e: and d, uniformly mixing the dried fine powder obtained in the step d to obtain dried powder, and obtaining a final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911319985.3A CN110833615A (en) | 2019-12-19 | 2019-12-19 | A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911319985.3A CN110833615A (en) | 2019-12-19 | 2019-12-19 | A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110833615A true CN110833615A (en) | 2020-02-25 |
Family
ID=69578515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911319985.3A Pending CN110833615A (en) | 2019-12-19 | 2019-12-19 | A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110833615A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114191533A (en) * | 2021-12-29 | 2022-03-18 | 潍坊医学院附属医院 | Navel treatment traditional Chinese medicine preparation for treating allergic rhinitis and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668160A (en) * | 2015-11-10 | 2017-05-17 | 顾立新 | External traditional Chinese medicinal prescription for treating chronic rhinitis |
-
2019
- 2019-12-19 CN CN201911319985.3A patent/CN110833615A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106668160A (en) * | 2015-11-10 | 2017-05-17 | 顾立新 | External traditional Chinese medicinal prescription for treating chronic rhinitis |
Non-Patent Citations (2)
| Title |
|---|
| 韩凤芹等: "针药并治鼻窒鼻鼽鼻渊52例", 《光明中医》 * |
| 黄宗勖: "《黄宗勖》", 31 August 2004, 中国中医药出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114191533A (en) * | 2021-12-29 | 2022-03-18 | 潍坊医学院附属医院 | Navel treatment traditional Chinese medicine preparation for treating allergic rhinitis and preparation method thereof |
| CN114191533B (en) * | 2021-12-29 | 2022-09-16 | 潍坊医学院附属医院 | Navel-therapy traditional Chinese medicine preparation for treating allergic rhinitis and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105012392A (en) | A kind of traditional Chinese medicine composition for treating rhinitis and preparation method thereof | |
| CN103316146B (en) | A kind of traditional Chinese medicine preparation for anesthesia | |
| CN104491676A (en) | Goiter-treating stasis-removing soup | |
| CN105168650A (en) | Traditional Chinese medicinal composition for anesthesia and analgesia for operations of general surgery | |
| CN103990103A (en) | Medicine for local anaesthesia and preparation method of medicine | |
| CN110833615A (en) | A Chinese medicinal composition for treating chronic rhinitis by umbilical therapy, and its preparation method | |
| CN103720762B (en) | Treat rhinitis fumigant and preparation method thereof | |
| CN106389881A (en) | Ointment capable of invigorating blood circulation and dissipating blood stasis | |
| CN110652544A (en) | Pharmaceutical composition for treating rhinitis and preparation method thereof | |
| CN108686058A (en) | Seven apertures rhinitis-treating spray and preparation method thereof | |
| CN108686009A (en) | Prevent and/or treat essential oil composition, preparation method, application and the preparation of rhinitis | |
| CN102225111B (en) | Traditional Chinese medicine granule for treating headache caused by rhinitis and preparation method thereof | |
| WO2021103777A1 (en) | Spraying agent for preventing and treating allergic asthma combined with allergic rhinitis in children and teenagers | |
| CN105561270A (en) | Analgesic Chinese herbal medicine for external application and preparation method thereof | |
| CN110384785A (en) | A kind of external application Chinese medicine medical fluid and preparation method thereof for treating virus flu | |
| CN103169905A (en) | Traditional Chinese medicine capsule preparation for treating lung-heart disease and preparation method thereof | |
| CN107625915A (en) | A kind of herbal ointment and preparation method thereof | |
| CN106110193A (en) | A kind of external skin ulcer convergence ointment and compound method thereof | |
| CN105687656A (en) | Pharmaceutical composition for treating myelitis and preparation method thereof | |
| CN104606447A (en) | Traditional Chinese medicine preparation for treating exogenous fever | |
| CN105641226A (en) | Hot-compress salt for treating dysmenorrhea and preparation method | |
| CN100490866C (en) | Ready prepared Chinese medicine for treating deep source nasal congestion | |
| CN104435232B (en) | A kind of traditional Chinese medicine composition for treating toothache | |
| CN103977223A (en) | Traditional Chinese medicinal composition for dispelling cold and dredging orifices and preparation method thereof | |
| CN104435855A (en) | Traditional Chinese medicine composition for treating viral myocarditis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200225 |
|
| RJ01 | Rejection of invention patent application after publication |