CN110743088B - Three-chamber double-balloon blood oxygenation in situ perfusion system - Google Patents

Abstract

The present invention relates to a perfusion system, in particular to a three-chamber double-balloon blood oxygenation in-situ perfusion system, and belongs to the technical field of blood oxygenation perfusion. An extraction perfusion catheter can be inserted into the superior vena cava and the inferior vena cava, and the superior vena cava and the inferior vena cava can be blocked as required through the first balloon and the second balloon, so that the blood in the superior vena cava and the inferior vena cava can be drawn out through the first blood extraction cavity and the second blood extraction cavity, respectively, and the extracted blood can be oxygenated with oxygen through the extraction-driven oxygenation perfusion mechanism, and after oxygenation, the blood can be perfused into the right atrium of the heart through the blood perfusion cavity and the blood perfusion hole, which can effectively realize the perfusion of blood after oxygenation and reduce the burden on the heart; during use, it is only necessary to puncture the femoral vein or the jugular vein, and then insert the extraction perfusion catheter into the required position in the superior vena cava and the inferior vena cava, which can effectively reduce trauma and is safe and reliable.

Description

Three-chamber double-balloon blood oxygenation in situ perfusion system

Technical Field

The invention relates to a perfusion system, in particular to a three-chamber double-bag blood oxygenation in-situ perfusion system, belonging to the technical field of blood oxygenation perfusion.

Background Art

Extracorporeal membrane oxygenation (ECMO) is a treatment modality that is commonly used in patients to replace or assist the respiratory and/or cardiac functions of medically disabled patients. In its broadest sense, ECMO uses one or more catheters and pump systems to draw blood out of the patient's body. The blood is then pumped through a gas exchanger where carbon dioxide (CO ₂ ) is removed from the blood and oxygen (O ₂ ) is added. The oxygenated blood is then pumped back into the patient's circulatory system where it can be distributed to the rest of the body. In some ECMO systems, blood is drawn from the venous system and returned to the arterial system. In other forms, blood is drawn from the venous system and returned to the venous system.

ECMO is usually achieved by percutaneously inserting a large-caliber cannula into a major peripheral vein or major peripheral artery of the body (e.g., femoral vein, subclavian vein, jugular vein; femoral artery, subclavian artery, etc.). However, many patients' right ventricles do not function properly, and/or there are major problems with pulmonary circulation, making this form of treatment ineffective. At the same time, for patients with pulmonary failure, etc., when blood is drawn from the femoral artery, the perfusion of the extraction site is reduced, which increases the patient's cardiac burden. In addition, when the existing ECMO is used, it is necessary to puncture and incise the cannula from multiple locations, which is very traumatic.

Summary of the invention

The purpose of the present invention is to overcome the deficiencies in the prior art and provide a three-chamber double-bag blood oxygenation in situ perfusion system, which has a compact structure, can effectively achieve perfusion after blood oxygenation, reduce cardiac burden, reduce trauma, and is safe and reliable.

According to the technical solution provided by the present invention, the three-chamber double-balloon blood oxygenation in-situ perfusion system comprises a blood extraction and perfusion mechanism and an extraction-driven oxygenation and perfusion mechanism adaptedly connected to the blood extraction and perfusion mechanism;

The blood extraction and perfusion mechanism comprises an extraction and perfusion tube that can be inserted into the superior vena cava and the inferior vena cava, a first capsule and a second capsule are arranged on the extraction and perfusion tube, the first capsule and the second capsule are wrapped on the circumferential outer wall of the extraction and perfusion tube, and the first capsule is adjacent to the head end of the extraction and perfusion tube; a first blood extraction cavity, a second blood extraction cavity and a blood perfusion cavity are arranged in the extraction and perfusion tube; the blood perfusion cavity is connected with the blood perfusion hole on the outer wall of the extraction and perfusion tube, and the blood perfusion hole is located between the first capsule and the second capsule; the second blood extraction cavity is connected with the blood extraction liquid inlet hole on the extraction and perfusion tube, and the blood extraction liquid inlet hole is located between the second capsule and the tail end of the extraction and perfusion tube, the first blood extraction cavity is distributed along the length direction of the extraction and perfusion tube, and the first blood extraction cavity passes through the extraction and perfusion tube;

After the extraction and perfusion catheter is placed in the superior vena cava and the inferior vena cava, the first balloon and the second balloon are respectively located on both sides of the blood inlet of the right atrium, and the first balloon and the second balloon can respectively block the venous cavities where they are located, and the blood perfusion holes correspond to the blood inlet of the right atrium; the extraction-driven oxygenation perfusion mechanism can respectively extract blood from the superior vena cava and the inferior vena cava through the first blood extraction cavity and the second blood extraction cavity, and the extracted blood can be oxygenated with oxygen in the extraction-driven oxygenation perfusion mechanism, and the oxygenated blood can be perfused into the right atrium of the heart through the blood perfusion cavity and the blood perfusion hole.

It also includes a first balloon inflation and deflation pipe that can be communicated with the first balloon and a second balloon inflation and deflation pipe that can be communicated with the second balloon. A first balloon inflation and deflation pipe sealing valve is provided on the first balloon inflation and deflation pipe, and the first balloon can be inflated or deflated as required through the first balloon inflation and deflation pipe sealing valve and the first balloon inflation and deflation pipe. A second balloon inflation and deflation pipe sealing valve is provided on the second balloon inflation and deflation pipe, and the second balloon can be inflated or deflated as required through the second balloon inflation and deflation pipe sealing valve and the second balloon inflation and deflation pipe.

A first connecting tube for blood extraction and placement connected to the first blood extraction cavity, a second connecting tube for blood extraction and placement connected to the second blood extraction cavity, and a connecting tube for blood perfusion and placement connected to the blood perfusion cavity are provided at the tail end of the extraction and perfusion placement tube;

The first connecting tube for blood extraction and placement and the second connecting tube for blood extraction and placement can be connected to the blood oxygenation tube group in the extraction-driven oxygenation perfusion mechanism. The blood oxygenation tube group includes a blood oxygenation circulation tube that allows blood to circulate and an oxygen circulation sleeve sleeved on the blood oxygenation circulation tube. The blood oxygenation circulation tube includes a water-blocking and breathable portion located in the oxygen circulation sleeve and blood circulation connecting portions located at both ends of the oxygen circulation sleeve. The oxygen entering the oxygen circulation tube from the oxygen inlet of the oxygen circulation sleeve can be oxygenated with the blood in the blood oxygenation circulation tube through the water-blocking and breathable portion. The oxygenated blood is perfused into the right atrium of the heart through the blood perfusion cavity and the blood perfusion hole through the oxygenated blood delivery drive device.

The liquid outlet of the oxygenated blood delivery drive device is connected to the blood perfusion tube through the oxygenated blood delivery tube; and also includes a blood heating device that can heat the blood in the oxygenated blood delivery tube.

It also includes a medicine injection port for injecting required medicine into the oxygenated blood delivery tube, a medicine injection port sealing cap for sealing the medicine injection port, and a free oxygen release port for releasing oxygen in the oxygen circulation tube, and an oxygen release switch for controlling the oxygen release state is arranged in the free oxygen release port.

A first connecting tube joint for blood extraction and placement is provided at the end of the first connecting tube for blood extraction and placement, the first connecting tube for blood extraction and placement is connected to one end of the first connecting tube for extraction and placement through the first connecting tube joint for blood extraction and placement, and the other end of the first connecting tube for extraction and placement is connected to the blood collection device for extraction and placement;

A second blood extraction tube connecting tube joint is provided at the end of the second blood extraction tube connecting tube. The second blood extraction tube connecting tube is connected to one end of the extraction driven second blood extraction tube connecting tube through the second blood extraction tube connecting head. The other end of the extraction driven second blood extraction tube is connected to the extraction driven blood receiver. The extraction driven blood receiver is connected to the blood oxygenation circulation tube. Blood extraction pressure measuring joints are provided on both the first blood extraction tube connecting tube and the second blood extraction tube connecting tube.

A blood extraction driver is provided on the first extraction drive connecting tube and/or the second extraction drive connecting tube.

A blood perfusion pressure measuring joint is arranged on the blood perfusion catheter connecting tube, and the blood heating device comprises a water bath heating structure.

When an extraction and perfusion tube is respectively inserted into the superior vena cava and the inferior vena cava, the blood perfusion hole of an extraction and perfusion tube corresponds to the blood inlet of the right atrium; a magnetic body is arranged at the head end of each extraction and perfusion tube, and the head ends of the two extraction and perfusion tubes are attracted to each other by the corresponding magnetic bodies and then aligned close to each other.

The water-blocking and breathable portion is made of a water-blocking and breathable film.

The advantages of the present invention are as follows: the extraction and perfusion catheter can be inserted into the superior vena cava and the inferior vena cava, and the superior vena cava and the inferior vena cava can be blocked as required through the first and second sacs, so that the blood in the superior vena cava and the inferior vena cava can be extracted through the first blood extraction cavity and the second blood extraction cavity respectively, and the extracted blood can be oxygenated with oxygen through the extraction-driven oxygenation and perfusion mechanism, and after oxygenation, the blood can be perfused into the right atrium of the heart through the blood perfusion cavity and the blood perfusion hole, which can effectively realize the perfusion of blood after oxygenation and reduce the burden on the heart; during use, it is only necessary to puncture the femoral vein or the jugular vein, and then insert the extraction and perfusion catheter into the required position in the superior vena cava and the inferior vena cava, which can effectively reduce trauma and is safe and reliable.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a stereoscopic view of the extraction and perfusion catheter of the present invention.

FIG. 2 is a schematic diagram of the structure of the extraction and perfusion catheter of the present invention.

FIG3 is a schematic diagram showing the distribution of the first blood extraction chamber, the second blood extraction chamber and the blood perfusion chamber in the extraction and perfusion catheter of the present invention.

FIG. 4 is a schematic diagram showing the distribution of the first blood extraction cavity and the blood perfusion cavity in the extraction and perfusion catheter of the present invention.

FIG. 5 is a schematic diagram of the first blood extraction chamber of the present invention within the extraction and perfusion catheter.

FIG. 6 is a perspective view of a specific implementation structure of the present invention.

FIG. 7 is a schematic diagram of the structure of FIG. 6 .

FIG8 is a schematic diagram of another specific implementation structure of the present invention.

FIG. 9 is a diagram showing a state of use of the present invention.

FIG. 10 is another usage state diagram of the present invention.

Explanation of the accompanying drawings: 1-extraction and perfusion catheter, 2-first sac, 3-second sac, 4-blood perfusion hole, 5-blood extraction liquid inlet hole, 6-first sac inflation and deflation tube, 7-first sac inflation and deflation tube sealing valve, 8-second sac inflation and deflation tube, 9-second sac inflation and deflation tube sealing valve, 10-blood extraction catheter first connecting tube, 11-blood extraction catheter first connecting tube joint, 12-blood perfusion catheter connecting tube, 13-blood perfusion catheter connecting tube joint, 14-blood extraction catheter second connecting tube, 15-blood extraction catheter second connecting tube joint, 16-blood extraction first cavity, 17-blood extraction second cavity, 18-blood Liquid perfusion cavity, 19-first bladder inflation and deflation tube built-in part, 20-second bladder inflation and deflation tube built-in part, 21-extraction drive first connecting tube, 22-extraction drive second connecting tube, 23-extraction drive blood receiver, 24-blood circulation connection part, 25-oxygen inlet, 26-oxygen circulation sleeve, 27-free oxygen release port, 28-oxygenated blood delivery drive device, 29-blood heating device, 30-medicine liquid injection connecting tube, 31-water-blocking and breathable part, 32-liquid extraction pressure measuring joint, 33-blood perfusion pressure measuring joint, 34-delivery perfusion connecting tube, 35-superior vena cava, 36-inferior vena cava and 37-heart.

DETAILED DESCRIPTION

The present invention will be further described below in conjunction with specific drawings and embodiments.

In order to effectively realize the perfusion of blood after oxygenation, reduce the burden on the heart and reduce trauma, the present invention includes a blood extraction and perfusion mechanism and an extraction drive oxygenation and perfusion mechanism adaptedly connected to the blood extraction and perfusion mechanism;

The blood extraction and perfusion mechanism comprises an extraction and perfusion tube 1 which can be inserted into the superior vena cava 35 and the inferior vena cava 36, a first sac 2 and a second sac 3 are arranged on the extraction and perfusion tube 1, the first sac 2 and the second sac 3 are wrapped around the circumferential outer wall of the extraction and perfusion tube 1, and the first sac 2 is adjacent to the head end of the extraction and perfusion tube 1; a first blood extraction cavity 16, a second blood extraction cavity 17 and a blood perfusion cavity 18 are arranged in the extraction and perfusion tube 1; the blood perfusion cavity 18 is connected with the blood perfusion hole 4 on the outer wall of the extraction and perfusion tube 1, and the blood perfusion hole 4 is located between the first sac 2 and the second sac 3; the second blood extraction cavity 17 is connected with the blood extraction liquid inlet hole 5 on the extraction and perfusion tube 1, and the blood extraction liquid inlet hole 5 is located between the second sac 3 and the tail end of the extraction and perfusion tube 1, and the first blood extraction cavity 16 is distributed along the length direction of the extraction and perfusion tube 1, and the first blood extraction cavity 16 passes through the extraction and perfusion tube 1;

After the extraction and perfusion catheter 1 is inserted into the superior vena cava 35 and the inferior vena cava 36, the first balloon 2 and the second balloon 3 are respectively located on both sides of the blood inlet of the right atrium, and the first balloon 2 and the second balloon 3 can respectively block the venous cavities where they are located, and the blood perfusion hole 4 corresponds to the blood inlet of the right atrium; the extraction-driven oxygenation perfusion mechanism can respectively extract the blood in the superior vena cava 35 and the inferior vena cava 36 through the blood extraction first cavity 16 and the blood extraction second cavity 17, and the extracted blood can be oxygenated with oxygen in the extraction-driven oxygenation perfusion mechanism, and the oxygenated blood can be perfused into the right atrium of the heart 37 through the blood perfusion cavity 18 and the blood perfusion hole 4.

Specifically, the blood extraction and perfusion mechanism and the extraction, drive and oxygenation perfusion mechanism must be made of materials that meet medical standards. The specific material type can be selected as needed, which is well known to those skilled in the art and will not be described in detail here.

The extraction and perfusion catheter 1 is tubular, and the extraction and perfusion catheter 1 can be placed in the superior vena cava 35 and the inferior vena cava 36, so as to extract blood from the superior vena cava 35 and the inferior vena cava 36. The first capsule 2 and the second capsule 3 are generally air bags, and the first capsule 2 and the second capsule 3 are annular, that is, the first capsule 2 and the second capsule 3 are wrapped on the circumferential outer wall of the extraction and perfusion catheter 1, the first capsule 2 is adjacent to the head end of the extraction and perfusion catheter 1, and the second capsule 3 is located between the first capsule 2 and the tail end of the extraction and perfusion catheter 1. Generally, the head end of the extraction and perfusion catheter 1 is the end that can be inserted into the superior vena cava 35 and the inferior vena cava 36, and when in use, the tail end of the extraction and perfusion catheter 1 is located outside the body.

A first blood extraction chamber 16, a second blood extraction chamber 17 and a blood perfusion chamber 18 are provided in the extraction and perfusion tube 1. The first blood extraction chamber 16, the second blood extraction chamber 17 and the blood perfusion chamber 18 are isolated from each other, that is, the first blood extraction chamber 16, the second blood extraction chamber 17 and the blood perfusion chamber 18 are not connected to each other. Generally, the first blood extraction chamber 16, the second blood extraction chamber 17 and the blood perfusion chamber 18 are distributed along the length direction of the extraction and perfusion tube 1. A blood perfusion hole 4 and a blood extraction liquid inlet hole 5 are also provided on the extraction and perfusion tube 1. The blood perfusion hole 4 is connected to the blood perfusion chamber 18, and the blood extraction liquid inlet hole 5 is connected to the second blood extraction chamber 17. Of course, the first blood extraction chamber 16 is connected to the end hole at the head end of the extraction and perfusion tube 1, as shown in Figures 1, 2, 3, 4 and 5. The blood perfusion hole 4 is located between the first sac body 2 and the second sac body 3, and the blood extraction liquid inlet hole 5 is located between the second sac body 3 and the tail end of the extraction and perfusion tube 1, that is, the blood can enter the blood extraction second cavity 17 through the blood extraction liquid inlet hole 5, and can enter the blood extraction first cavity 16 through the end hole at the head end of the extraction and perfusion tube 1. The blood entering the blood perfusion cavity 18 can pass through the blood perfusion hole 4 to carry out the required blood perfusion output.

In the embodiment of the present invention, the extraction and perfusion catheter 1 can be inserted through the femoral vein, at which time, the head end of the extraction and perfusion catheter 1 is located in the superior vena cava 35, and the second capsule 3 is located in the inferior vena cava 36, as shown in Figure 10; or, the extraction and perfusion catheter 1 can be inserted through the jugular vein, at which time, the head end of the extraction and perfusion catheter 1 is located in the inferior vena cava 36, and the second capsule 3 is located in the superior vena cava 35, as shown in Figure 9. That is, when the first capsule 2 and the second capsule 3 are inserted after puncture at different positions, the positions of the first capsule 2 and the second capsule 3 are different, but the first capsule 2 and the second capsule 3 can block the venous lumen. That is, the superior vena cava 35 or the inferior vena cava 36 can be blocked by the first balloon 2, and the inferior vena cava 36 or the superior vena cava 35 can be blocked by the second balloon 3. Regardless of the positions of the first balloon 2 and the second balloon 3, the blood perfusion hole 4 on the extraction and perfusion catheter 1 needs to correspond to the blood inlet of the right atrium, so that the oxygenated blood can be perfused into the blood inlet of the right atrium through the blood perfusion hole 4.

During specific implementation, the extraction and perfusion catheter 1 is inserted into the corresponding positions of the superior vena cava 35 and the inferior vena cava 36 according to the required position. The extraction-driven oxygenation perfusion mechanism can provide the power for blood extraction and perfusion, and can realize oxygenation of oxygen and blood after extraction, and can perfuse the oxygenated blood into the right atrium of the heart 37 through the blood perfusion cavity 18 and the blood perfusion hole 4. After the oxygenated blood is perfused into the right atrium of the heart 37, the specific flow of blood is consistent with the existing ones, which is well known to those skilled in the art and will not be described here. By oxygenating blood after blood extraction, perfusion of oxygenated blood can be effectively achieved, which is particularly suitable for situations of lung failure or decreased cardiac function performance, and reduces the burden on the heart. When in use, it only needs to be inserted from the femoral vein or jugular vein, which can effectively reduce trauma.

As shown in Figures 1, 2, 3, 4 and 5, it also includes a first balloon inflation and deflation pipe 6 that can be communicated with the first balloon 2 and a second balloon inflation and deflation pipe 8 that can be communicated with the second balloon 3. A first balloon inflation and deflation pipe sealing valve 7 is arranged on the first balloon inflation and deflation pipe 6, and the first balloon 2 can be inflated or deflated as required through the first balloon inflation and deflation pipe sealing valve 7 and the first balloon inflation and deflation pipe 6. A second balloon inflation and deflation pipe sealing valve 9 is arranged on the second balloon inflation and deflation pipe 8, and the second balloon 3 can be inflated or deflated as required through the second balloon inflation and deflation pipe sealing valve 9 and the second balloon inflation and deflation pipe 8.

In the embodiment of the present invention, initially, the first balloon 2 and the second balloon 3 need to be in an empty state, and only when the extraction and perfusion tube 1 is placed in the desired position, the first balloon 2 and the second balloon 3 need to be in a filled state. The first balloon inflation and deflation tube 6 is connected and communicated with the first balloon 2, and the process of inflating and deflation of the first balloon 2 through the first balloon inflation and deflation tube sealing valve 7 and the first balloon inflation and deflation tube 6 is consistent with the existing, and is specifically well known to personnel in the technical field, and will not be repeated here. Similarly, the second balloon 3 can be inflated and deflated through the second balloon inflation and deflation tube 8 and the second balloon inflation and deflation tube sealing valve 9. The portion of the first balloon inflation and deflation tube 6 located in the extraction and perfusion tube 1 is the first balloon inflation and deflation tube built-in portion 19, and the portion of the second balloon inflation and deflation tube 8 buried in the extraction and perfusion tube 1 forms the second balloon inflation and deflation tube built-in portion 20.

As shown in Figures 9 and 10, when the first balloon 2 and the second balloon 3 are in a filled state, the first balloon 2 and the second balloon 3 can block the blood in the superior vena cava 35 and the inferior vena cava 36 from flowing directly into the liquid inlet of the right atrium, so that the blood in the superior vena cava 35 and the inferior vena cava 36 can be extracted respectively through the first blood extraction chamber 16 and the second blood extraction chamber 17, which is convenient for subsequent blood oxygenation, and after oxygenation, the oxygenated blood is perfused into the right atrium of the heart 37 through the blood perfusion chamber 18 and the blood perfusion hole 4.

As shown in Fig. 6, Fig. 7 and Fig. 8, a first connecting tube 10 for blood extraction tube connected to the first blood extraction cavity 16, a second connecting tube 14 for blood extraction tube connected to the second blood extraction cavity 17 and a connecting tube 12 for blood perfusion tube connected to the blood perfusion cavity 18 are provided at the tail end of the extraction and perfusion tube 1;

The first blood extraction tube connecting tube 10 and the second blood extraction tube connecting tube 14 can be connected to the blood oxygenation tube group in the extraction drive oxygenation perfusion mechanism. The blood oxygenation tube group includes a blood oxygenation circulation tube that allows blood to circulate and an oxygen circulation sleeve 26 sleeved on the blood oxygenation circulation tube. The blood oxygenation circulation tube includes a water-blocking and breathable portion 31 located in the oxygen circulation sleeve 26 and blood circulation connecting portions 24 located at both ends of the oxygen circulation sleeve 26. The oxygen entering the oxygen circulation sleeve 26 from the oxygen inlet 25 of the oxygen circulation sleeve 26 can be oxygenated with the blood in the blood oxygenation circulation tube through the water-blocking and breathable portion 31. The oxygenated blood is perfused into the right atrium of the heart 37 through the blood perfusion cavity 18 and the blood perfusion hole 4 through the oxygenated blood delivery drive device 28.

In the embodiment of the present invention, the first blood extraction tube connecting tube 10, the second blood extraction tube connecting tube 14 and the blood perfusion tube connecting tube 12 are located at the tail end of the extraction and perfusion tube 1, and can be connected to the first blood extraction cavity 16 through the first blood extraction tube 10, can be connected to the second blood extraction cavity 17 through the second blood extraction tube connecting tube 14, and can be connected to the blood perfusion cavity 18 through the blood perfusion tube connecting tube 12, so that the first blood extraction tube connecting tube 10, the second blood extraction tube connecting tube 14 and the blood perfusion tube connecting tube 12 can be connected to the extraction drive oxygenation perfusion mechanism accordingly.

In specific implementation, the extraction drive oxygenation perfusion mechanism includes a blood oxygenation perfusion and oxygenated blood delivery drive device 28, wherein the first blood extraction tube connection tube 10 and the second blood extraction tube connection tube 14 can be connected to the blood oxygenation tube group, that is, blood can enter the blood oxygenation tube group after being respectively extracted through the first blood extraction tube connection tube 10 and the second blood extraction tube connection tube 14. The blood oxygenation tube group includes an oxygen circulation sleeve 26 and a blood oxygenation circulation tube, the length of the blood oxygenation circulation tube is greater than that of the oxygen circulation sleeve 26, and the diameter of the oxygen circulation sleeve 26 is greater than that of the water-blocking and breathable part 31, and blood can enter the water-blocking and breathable part 31 through the blood circulation connection part 24 at one end of the oxygen circulation sleeve 26, and flow out from the blood circulation connection part 24 at the other end of the blood circulation tube 26 into the oxygenated blood delivery drive device 28.

Oxygen enters the oxygen circulation sleeve 26 through the oxygen inlet 25. The oxygen entering the oxygen circulation sleeve 26 can combine with the blood in the water-blocking and breathable portion 31 through the water-blocking and breathable portion 31 to achieve blood oxygenation. The oxygenated blood can enter the oxygenated blood delivery drive device 28, and the oxygenated blood delivery drive device 28 can drive the oxygenated blood to be perfused into the right atrium of the heart 37 through the blood perfusion cavity 18 and the blood perfusion hole 4.

The water-blocking and breathable portion 31 is made of a water-blocking and breathable film. In a specific implementation, the entire tube wall or part of the tube wall of the water-blocking and breathable portion 31 is made of a water-blocking and breathable film. The water-blocking and breathable film can prevent blood from entering the oxygen circulation sleeve 26 without affecting the oxygenation of blood. In addition, after the blood is blocked by the water-blocking and breathable portion 31, the contact area between blood and oxygen can be increased, and the reliability of blood oxygenation can be improved. The water-blocking and breathable membrane can adopt an existing commonly used structural form, as long as it can block the blood from flowing into the oxygen circulation sleeve 26 without affecting the oxygenation of blood. The specific structure is well known to those skilled in the art and will not be described here.

Furthermore, the liquid outlet of the oxygenated blood delivery drive device 28 is adaptably connected to the blood perfusion tube connection tube 12 through the oxygenated blood delivery tube 34; and also includes a blood heating device 29 that can heat the blood in the oxygenated blood delivery tube 34.

In the embodiment of the present invention, the oxygenated blood delivery driving device 28 can be connected to the blood perfusion cannula connecting tube 12 through the oxygenated blood delivery tube 34, so that the oxygenated blood can enter the blood perfusion chamber 18 through the oxygenated blood delivery tube 34 and the blood perfusion cannula connecting tube 12. The oxygenated blood delivery driving device 28 can be a peristaltic pump, a centrifugal pump, or other forms that can provide power for blood delivery. The specific type of the oxygenated blood delivery driving device 28 can be selected as needed, and will not be described in detail here.

The blood in the oxygenated blood delivery tube 34 can be heated by the blood heating device 29. The blood heating device 29 includes a water bath heating structure. The water bath heating structure generally includes hot water for heating, etc. The specific structural form can be selected according to needs, as long as it can achieve heating of the blood in the oxygenated blood delivery tube 34. The specific structure is well known to those skilled in the art and will not be described here. A blood perfusion pressure measuring joint 33 is provided on the blood perfusion catheter connection tube 12. The blood perfusion pressure measuring joint 33 can be connected to a blood pressure measuring device. The device for blood measurement can be in the form of a blood pressure measuring sensor or a pressure gauge. The specific form of the blood perfusion pressure measuring joint 33 can be adapted to the blood measurement device. After the blood perfusion pressure measuring joint 33 cooperates with the blood measurement device, the blood pressure entering the blood perfusion chamber 18 can be measured, and the blood entering the blood perfusion chamber 18 can be monitored.

Furthermore, it also includes a medicine injection port for injecting required medicine into the oxygenated blood delivery tube 34, a medicine injection port sealing cap for sealing the medicine injection port, and a free oxygen release port 27 for releasing oxygen in the oxygen circulation sleeve 26, and an oxygen release switch for controlling the oxygen release state is provided in the free oxygen release port 27.

In the embodiment of the present invention, a number of medical solutions can be injected into the oxygenated blood delivery tube 34 through the medical solution injection port. Generally, a medical solution injection connecting tube 30 can be provided on the oxygenated blood delivery tube 34, and a medical solution injection port can be formed through the medical solution injection connecting tube 30. The medical solution injection connecting tube 30 can be closed by a medical solution injection port sealing cap matched with the medical solution injection connecting tube 30, that is, when the required medical solution needs to be injected, the medical solution injection port sealing cap is separated from the medical solution injection connecting tube 30, and after the injection of the medical solution is completed, the medical solution injection port sealing cap is installed on the medical solution injection connecting tube 30 to ensure the reliability before and after the injection of the medical solution.

The free oxygen release port 27 and the oxygen inlet port 25 are respectively located at the two ends of the oxygen circulation sleeve 26. Oxygen can enter the oxygen circulation sleeve 26 through the oxygen inlet port 25, and oxygen that is not oxygenated with blood is released through the free oxygen release port 27, thereby avoiding gas embolism caused by free oxygen entering the oxygen-blood delivery tube 34. The oxygen release switch can be in the form of a manual valve or a solenoid valve, etc., and the oxygen state released through the free oxygen release port 27 can be effectively controlled by the oxygen release switch to ensure the reliability of the blood oxygenation process.

Furthermore, a first blood extraction tube connecting pipe joint 11 is provided at the end of the first blood extraction tube connecting pipe 10, and the first blood extraction tube connecting pipe 10 is connected to one end of the extraction drive first connecting pipe 21 through the first blood extraction tube connecting pipe joint 11, and the other end of the extraction drive first connecting pipe 21 is connected to the extraction drive blood receiver 23;

A blood extraction tube second connecting tube joint 15 is provided at the end of the blood extraction tube second connecting tube 14, and the blood extraction tube second connecting tube 14 is connected to one end of the extraction drive second connecting tube 22 through the blood extraction tube second connecting head 15, and the other end of the extraction drive second connecting tube 22 is connected to the extraction drive blood receiver 23, and the extraction drive blood receiver 23 is connected to the blood oxygenation circulation tube; blood extraction pressure measuring joints 32 are provided on both the blood extraction tube first connecting tube 10 and the blood extraction tube second connecting tube 14.

In the embodiment of the present invention, the extraction-driven blood receiver 23 can be a non-powered blood storage container, or a blood extraction driver that can provide blood extraction capability. The specific selection can be made according to needs, and will not be repeated here. When the extraction-driven blood receiver 23 adopts a blood extraction driver, the blood in the superior vena cava 35 and the inferior vena cava 36 can be extracted under the action of the extraction-driven blood receiver 23, and enter the extraction-driven blood receiver 23 through the extraction-driven first connecting tube 21 and the extraction-driven second connecting tube 22; at this time, the extraction-driven blood receiver 23 can adopt the form of a commonly used pump body. When the extraction-driven blood receiver 23 is a non-powered blood storage container, the extracted blood will be concentrated in the extraction-driven blood receiver 23. After the blood in the superior vena cava 35 and the inferior vena cava 36 is extracted, it can enter the blood oxygenation tube group through the extraction-driven blood receiver 23 for subsequent oxygenation with oxygen.

In specific implementation, a blood extraction pressure measuring joint 32 is provided on both the first blood extraction tube connecting tube 10 and the second blood extraction tube connecting tube 14. The blood pressure of the blood passing through the first blood extraction tube connecting tube 10 and the second blood extraction tube connecting tube 14 can be measured respectively through the blood extraction pressure measuring joint 32, so that blood monitoring can be achieved during the entire blood extraction process. A blood perfusion tube connecting tube joint 13 is provided at the end of the blood perfusion tube connecting tube 12. The blood perfusion tube connecting tube 12 can be adapted and connected to the oxygenated blood delivery tube 34 through the blood perfusion tube connecting tube joint 13.

In addition, a blood extraction driver is provided on the first extraction drive connecting tube 21 and/or the second extraction drive connecting tube 22. In the embodiment of the present invention, the blood extraction driver can adopt the above-mentioned peristaltic pump, centrifugal pump or other pump body capable of realizing blood extraction or extraction drive, which can be selected according to actual needs and will not be described in detail here. When the blood extraction driver is provided on both the first extraction drive connecting tube 21 and the second extraction drive connecting tube 22, the blood extraction driver can provide extraction power for the blood extracted from the superior vena cava 35 and the inferior vena cava 36.

Furthermore, when an extraction and perfusion tube 1 is respectively inserted into the superior vena cava 35 and the inferior vena cava 36, the blood perfusion hole 4 of an extraction and perfusion tube 1 corresponds to the blood inlet of the right atrium; a magnetic body is arranged at the head end of each extraction and perfusion tube 1, and the head ends of the two extraction and perfusion tubes 1 are attracted to each other by the corresponding magnetic bodies and then aligned close to each other.

In the embodiment of the present invention, when blood is extracted, oxygenated and perfused, the stability of one extraction and perfusion catheter 1 in the superior vena cava 35 and the inferior vena cava 36 is relatively low. In actual work, two extraction and perfusion catheters 1 can be used, and the head ends of the two extraction and perfusion catheters 1 are connected by magnetic attraction. The mutual connection of the two extraction and perfusion catheters 1 can improve the stability and reliability in the superior vena cava 35 and the inferior vena cava 36. After the two extraction and perfusion catheters 1 are connected by magnetic attraction, they can also achieve the function of the above-mentioned one extraction and perfusion catheter 1, that is, the two extraction and perfusion catheters 1 need to extract blood from the superior vena cava 35 and the inferior vena cava 36, and after extraction, the oxygenated blood can be perfused into the right atrium again, so that the specific position state of the two extraction and perfusion catheters 1 in the superior vena cava 35 and the inferior vena cava 36 can be selected according to needs, which will not be repeated here.

Claims (8)

1. A three-chamber double-balloon blood oxygenation in-situ perfusion system, characterized by: comprising a blood extraction and perfusion mechanism and an extraction-driven oxygenation and perfusion mechanism adaptedly connected to the blood extraction and perfusion mechanism; The blood extraction and perfusion mechanism comprises an extraction and perfusion catheter (1) which can be inserted into the superior vena cava (35) and the inferior vena cava (36); a first sac (2) and a second sac (3) are arranged on the extraction and perfusion catheter (1); the first sac (2) and the second sac (3) are wrapped around the circumferential outer wall of the extraction and perfusion catheter (1); the first sac (2) is adjacent to the head end of the extraction and perfusion catheter (1); a first blood extraction cavity (16), a second blood extraction cavity (17) and a blood perfusion cavity (18) are arranged in the extraction and perfusion catheter (1); the blood perfusion cavity ( 18) is connected to the blood perfusion hole (4) on the outer wall of the extraction and perfusion tube (1), and the blood perfusion hole (4) is located between the first sac (2) and the second sac (3); the second blood extraction cavity (17) is connected to the blood extraction liquid inlet hole (5) on the extraction and perfusion tube (1), and the blood extraction liquid inlet hole (5) is located between the second sac (3) and the tail end of the extraction and perfusion tube (1); the first blood extraction cavity (16) is distributed along the length direction of the extraction and perfusion tube (1), and the first blood extraction cavity (16) passes through the extraction and perfusion tube (1); After the extraction and perfusion catheter (1) is placed in the superior vena cava (35) and the inferior vena cava (36), the first sac (2) and the second sac (3) are respectively located on both sides of the blood inlet of the right atrium, and the first sac (2) and the second sac (3) can respectively block the venous cavities where they are located, and the blood perfusion hole (4) corresponds to the blood inlet of the right atrium; the extraction-driven oxygenation perfusion mechanism can respectively extract blood from the superior vena cava (35) and the inferior vena cava (36) through the first blood extraction cavity (16) and the second blood extraction cavity (17), and the extracted blood can be oxygenated with oxygen in the extraction-driven oxygenation perfusion mechanism, and the oxygenated blood can be perfused into the right atrium of the heart (37) through the blood perfusion cavity (18) and the blood perfusion hole (4); It also includes a first balloon inflation/deflation pipe (6) that can be communicated with the first balloon (2) and a second balloon inflation/deflation pipe (8) that can be communicated with the second balloon (3); a first balloon inflation/deflation pipe sealing valve (7) is provided on the first balloon inflation/deflation pipe (6); the first balloon (2) can be inflated or deflated as required through the first balloon inflation/deflation pipe sealing valve (7) and the first balloon inflation/deflation pipe (6); a second balloon inflation/deflation pipe sealing valve (9) is provided on the second balloon inflation/deflation pipe (8); the second balloon (3) can be inflated or deflated as required through the second balloon inflation/deflation pipe sealing valve (9) and the second balloon inflation/deflation pipe (8); A first blood extraction tube connecting tube (10) connected to a first blood extraction chamber (16), a second blood extraction tube connecting tube (14) connected to a second blood extraction chamber (17), and a blood perfusion tube connecting tube (12) connected to a blood perfusion chamber (18) are provided at the tail end of the extraction and perfusion tube (1); The first blood extraction tube connecting tube (10) and the second blood extraction tube connecting tube (14) can be connected to the blood oxygenation tube group in the extraction drive oxygenation perfusion mechanism. The blood oxygenation tube group includes a blood oxygenation circulation tube that allows blood to circulate and an oxygen circulation sleeve (26) sleeved on the blood oxygenation circulation tube. The blood oxygenation circulation tube includes a water-blocking and breathable portion (31) located in the oxygen circulation sleeve (26) and blood circulation connecting portions (24) located at both ends of the oxygen circulation sleeve (26). Oxygen entering the oxygen circulation tube (26) from the oxygen inlet (25) of the oxygen circulation sleeve (26) can be oxygenated with the blood in the blood oxygenation circulation tube through the water-blocking and breathable portion (31). The oxygenated blood is perfused into the right atrium of the heart (37) through the blood perfusion cavity (18) and the blood perfusion hole (4) through the oxygenated blood delivery drive device (28). 2. The three-chamber double-balloon blood oxygenation in-situ perfusion system according to claim 1 is characterized in that: the liquid outlet of the oxygenated blood delivery drive device (28) is adaptively connected to the blood perfusion catheter connection tube (12) through the oxygenated blood delivery tube (34); and also includes a blood heating device (29) that can heat the blood in the oxygenated blood delivery tube (34). 3. The three-chamber double-balloon blood oxygenation in-situ perfusion system according to claim 2 is characterized in that it also includes a liquid medicine injection port for injecting the required liquid medicine into the oxygenated blood delivery tube (34), a liquid medicine injection port sealing cap for blocking the liquid medicine injection port, and a free oxygen release port (27) for releasing the oxygen in the oxygen circulation tube (26), and an oxygen release switch for controlling the oxygen release state is arranged in the free oxygen release port (27). 4. The three-chamber double-balloon blood oxygenation in-situ perfusion system according to claim 1 is characterized in that: a first connecting tube joint (11) for blood extraction and placement is provided at the end of the first connecting tube (10) for blood extraction and placement, the first connecting tube (10) for blood extraction and placement is connected to one end of the first connecting tube (21) for extraction and placement through the first connecting tube joint (11), and the other end of the first connecting tube (21) for extraction and placement is connected to the blood collection device (23) for extraction and placement; A second blood extraction tube connecting tube joint (15) is provided at the end of the second blood extraction tube connecting tube (14); the second blood extraction tube connecting tube (14) is connected to one end of the extraction drive second connecting tube (22) via the second blood extraction tube connecting tube joint (15); the other end of the extraction drive second connecting tube (22) is connected to an extraction drive blood receiver (23); and the extraction drive blood receiver (23) is connected to a blood oxygenation circulation tube; blood extraction pressure measuring joints (32) are provided on both the first blood extraction tube connecting tube (10) and the second blood extraction tube connecting tube (14). 5. The three-chamber double-balloon blood oxygenation in-situ perfusion system according to claim 4, characterized in that a blood extraction driver is arranged on the first extraction drive connecting tube (21) and/or the second extraction drive connecting tube (22). 6. The three-chamber double-balloon blood oxygenation in-situ perfusion system according to claim 2 is characterized in that: a blood perfusion pressure measuring joint (33) is provided on the blood perfusion catheter connecting tube (12), and the blood heating device (29) includes a water bath heating structure. 7. The three-chamber double-balloon blood oxygenation in situ perfusion system according to claim 1 is characterized in that: when an extraction and perfusion tube (1) is respectively inserted into the superior vena cava (35) and the inferior vena cava (36), the blood perfusion hole (4) of an extraction and perfusion tube (1) corresponds to the blood inlet of the right atrium; a magnetic body is arranged at the head end of each extraction and perfusion tube (1), and the head ends of the two extraction and perfusion tubes (1) are attracted to each other by the corresponding magnetic bodies and then aligned close to each other. 8. The three-chamber double-balloon blood oxygenation in-situ perfusion system according to claim 1, characterized in that: the water-blocking and breathable portion (31) is made of a water-blocking and breathable membrane.