CN105597175A

CN105597175A - Hemodialysis device

Info

Publication number: CN105597175A
Application number: CN201610106083.1A
Authority: CN
Inventors: 陈锋
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-02-26
Filing date: 2016-02-26
Publication date: 2016-05-25
Anticipated expiration: 2036-02-26
Also published as: CN105597175B

Abstract

The invention discloses a hemodialysis device. The hemodialysis device comprises a dialysate tank, a dialysate induction catheter, a dialysis catheter, a dialysate eduction catheter and a peristaltic pump; the dialysate tank is connected with the dialysate induction catheter, the outlet end of the dialysate induction catheter and the inlet end of the dialysate eduction catheter are connected with the dialysis catheter, the dialysate eduction catheter is connected with the peristaltic pump, and the peristaltic pump is connected with the dialysate tank; the dialysis catheter comprises a permeable inner tube, a dialysis membrane and a permeable outer tube, the tube wall of the permeable inner tube is wrapped with the dialysis membrane, the permeable inner tube is sleeved with the permeable outer tube, the inlet end and the outlet end of the permeable inner tube are arranged on the same side in the permeable outer tube, the inlet end of the permeable inner tube is connected with the dialysate induction catheter, and the outlet end of the permeable inner tube is connected with the dialysate eduction catheter. The hemodialysis device further comprises Y-shaped lock catches. According to the hemodialysis device, the dialysis catheter is arranged in the artery in a human body during dialysis, hemodialysis is completed in blood vessels, blood does not need to be drawn out of the body for hemodialysis, influence on the blood pressure of the human body does not exist, and the hemodialysis device is more economical and safer.

Description

A kind of haemodialysis equipment

Technical field

The present invention relates to Medical Devices technical field, relate in particular to a kind of haemodialysis equipment.

Background technology

The main flow therapy of removing at present oedema mainly comprises two kinds: 1. drug diuresis: use medicine to make patient's hydrouria, thereby excessive moisture in body is excreted by the approach of " blood-kidney-urine "; 2. extracorporeal blood dialysis: the blood in patient body is extracted out, through the filtration of extracorporal dialysis instrument, the excessive moisture in blood is filtered, the remaining blood through " concentrating " feeds back in body again, thereby reaches the object of removing oedema.

Haemodialysis is also the common method for the treatment of acute and chronic kidney merit exhaustion (uremia) and acute drugs poisoning and pesticide poisoning. China has up to ten million Chronic Renal Failure Patients to sustain life with CHD every year at present, and has the trend of increasing year by year. Haemodialysis principle: the solution that dialysis refers to pellicle both sides is by disperse, infiltration and ultrafiltration, be that solute is by the high low side flow of a side direction concentration of concentration, and the process of the high side flow of the side direction osmotic pressure that hydrone is forced down by infiltration finally reaches dynamic equilibrium. Haemodialysis reaches therapeutic purposes by solution disperse and ultrafiltration between blood and dislysate.

Mainly there is following shortcoming in the therapy of prior art: 1. drug diuresis method: shortcoming is to be prone to toxic and side effect and resistance phenomenon after using in a large number medicine, or because critical patient is often associated with kidney failure, blocked the diuresis approach of appeal, causes diuretic effect not good; 2. extracorporeal blood dialysis process: (1) is external owing to blood will being extracted out, then feeds back in patient body, can cause blood volume in patient body sharply reduce or raise during this time, causes unstable blood pressure even to cause death; (2) extracorporal dialysis process can only continue several hours conventionally, cannot continue, for a long time, reposefully for patient gives excessive moisture; (3) extracorporal dialysis instrument is huge, is difficult to transport, needs specially patient to be delivered to dialysate chamber, or huge extracorporal dialysis machine is transported to patient bedside, increases treatment difficulty; (4) instrument is expensive, reaches hundreds thousand of even millions of.

Summary of the invention

Goal of the invention of the present invention is: for the problem of above-mentioned existence, provide a kind of haemodialysis equipment. Dialysis tubing in haemodialysis equipment of the present invention is placed in artery in human body in the time of dialysis, directly in blood vessel, complete haemodialysis in vivo, and externally carry out hemodialysis through machine again without blood is extracted out, thereby on human blood-pressure without impact,, safety more more economical than external hemodialysis and wound are little.

In order to realize foregoing invention object, the technical solution used in the present invention is as follows:

A kind of haemodialysis equipment, comprise dialysis liquid bath, dislysate ingress pipe, dialysis tubing, dislysate delivery line and peristaltic pump, described dialysis liquid bath is connected with dislysate ingress pipe entrance point, the dislysate ingress pipe port of export is connected with dialysis tubing respectively with the arrival end of dislysate delivery line, the port of export of dislysate delivery line is connected with peristaltic pump, and peristaltic pump is connected with dialysis liquid bath by conduit; Described dialysis tubing comprises permeability inner tube, dialysis membrane and permeability outer tube, described dialysis membrane is wrapped in outside permeability inner pipe wall, described permeability outer tube sleeve is in permeability inner tube periphery, the arrival end of described permeability inner tube and the port of export are arranged at the same side in permeability outer tube, the arrival end of described permeability inner tube is connected with the port of export of dislysate ingress pipe, and the port of export of permeability inner tube is connected with the arrival end of dislysate delivery line; Described haemodialysis equipment also comprises Y type snap close, and one end of Y type snap close is enclosed within permeability outer tube periphery, and the two ends of bifurcated are enclosed within respectively the periphery of dislysate ingress pipe and dislysate delivery line.

The operation principle of haemodialysis equipment of the present invention is: before patient is dialysed, first by puncture, dialysis tubing is inserted in human body in femoral artery or radial artery with seal wire or sheath pipe, dialysis tubing can retain about a week in artery as required in vivo, then with Y type snap close, dislysate ingress pipe and dislysate delivery line and permeability outer tube are connected, and dislysate ingress pipe is guided into the arrival end of permeability inner tube, dislysate delivery line is guided into the port of export of permeability inner tube, connect other parts simultaneously, open peristaltic pump, in dialysis liquid bath, dislysate is inputted by dislysate ingress pipe in the permeability inner tube of dialysis tubing, in the permeability inner tube of dialysis tubing, be now the dislysate of hyperosmosis, blood enters permeability outer tube, be that permeability inner tube is outward the lower blood of osmotic pressure (containing great quantities of spare moisture), middle across dialysis membrane, dialysis membrane only allows that the hydrone of molecular weight passes through, most of macromolecule composition in blood can not pass through, excessive moisture in blood is sustainable like this infiltrates through in dislysate, leave blood, and along with dislysate delivery line transfers out external, reach dialysis object, meanwhile in pipe, the dislysate of high concentration continues to upgrade by flowing, and keeps higher permeable pressure head, reaches and continues the effect of dialysing. in the time that needs stop dialysing, close peristaltic pump, folder locking button, snap close is made up of flexible material, realizes the temporary transient cutout of dislysate.

Further, the arrival end of described permeability outer tube relative permeability inner tube and the opposite side at port of export place are also provided with hard plastic stub bar. Acting as in the time that dialysis tubing is inserted in human vas of hard plastic stub bar, plays the effect of breakthrough, prevents that tube head is excessively soft, inserts and does not enter blood vessel.

Further, on described dislysate ingress pipe, be provided with dislysate flow speed control valve. Control the flow velocity of dislysate by dislysate flow speed control valve is set, when ensureing dialytic efficiency, alleviate patient's misery.

Further, described dialysis liquid bath is outside equipped with temperature regulating device. By the temperature of temperature regulating device control dislysate, ensure the normal temperature demand of blood when patient dialyses.

Further, described permeability inner tube comprises straight tube and bend pipe, and straight tube and bend pipe are integrated, and bend pipe is looped around straight tube periphery in the shape of a spiral. The structure of permeability inner tube of the present invention can fully improve the contact area of blood and dislysate, effectively improves the dialytic efficiency of blood.

Further, the tube wall of described permeability outer tube is hollow out paliform, and the tube wall of described permeability inner tube is that hollow out is latticed, and the material of described inner and outer tubes is polyureas amine ester. The polyureas amine ester that the present invention adopts has stable chemical performance, good biocompatibility, the feature such as smooth surface and elasticity and hydrophily are good.

Further, on described dislysate ingress pipe and dislysate delivery line, be provided with snap close.

Further, on described dislysate ingress pipe and dislysate delivery line, be provided with knob. Knob of the present invention is auxiliary to be separated dialysis tubing completely with dislysate ingress pipe and dislysate delivery line.

Further, the diameter of described permeability inner tube is 0.5 ~ 2mm, and length is 200 ~ 300mm.

Further, the diameter of described permeability outer tube is 3 ~ 5mm, and length is 150 ~ 300mm.

The material of dialysis membrane of the present invention is polyether sulfone. The polyether sulphone hollow fibre film that adopts biofacies compatibility and the better novel high polymer material of dialysis function to make, due to the effect of the oxygen-ether linkage in polyether sulfone materials molecular structure, its hydrophily and heat resistance, decay resistance further improve, while contact with blood, protein adsorption reduces, especially in the time contacting with strong oxidizer, no longer produce free radical, activation to complement is few, has better convection current and disperse performance.

In sum, owing to having adopted technique scheme, the invention has the beneficial effects as follows:

(1) haemodialysis equipment of the present invention can be realized body inner blood dialysis, externally carries out hemodialysis through machine again without blood is extracted out, thus on human blood-pressure without impact, greatly improved the security of haemodialysis;

(2) dialysis tubing in haemodialysis equipment of the present invention is a kind of portable, disposable cast parts, the object that reaches beside sickbed dialysis, allows patient can directly accept on one's sick bed dialysis treatment, can be used for rescue, severe treatment, and reduction medical expense, safety, mild, effective;

(3) haemodialysis equipment of the present invention has advantages of reasonable in design, easy to use, is a kind of desirable haemodialysis utensil, can be widely used in clinical.

Brief description of the drawings

Examples of the present invention will be described by way of reference to the accompanying drawings, wherein:

Fig. 1 is the structural representation of haemodialysis equipment of the present invention;

Fig. 2 is the annexation figure that haemodialysis equipment dialysis tubing of the present invention and dislysate import and export pipe;

Fig. 3 is the structural representation of dialysis tubing of the present invention;

Fig. 4 is the dialyse partial enlarged drawing of dialysis membrane and inner tube of the present invention.

Wherein, 1-dialysis liquid bath; 2-dislysate ingress pipe; 3-dialysis tubing; 4-dislysate delivery line; 5-peristaltic pump; 6-permeability outer tube; 7-permeability inner tube; 8-dialysis membrane; 9-Y type snap close; 10-dislysate flow speed control valve; 11-hard plastic stub bar; 12-knob; 13-snap close.

Detailed description of the invention

As shown in Fig. 1 ~ 4, a kind of haemodialysis equipment, comprise dialysis liquid bath 1, dislysate ingress pipe 2, dialysis tubing 3, dislysate delivery line 4 and peristaltic pump 5, dialysis liquid bath 1 is connected with dislysate ingress pipe 2 entrance points, dislysate ingress pipe 2 ports of export are connected with dialysis tubing 3 respectively with the arrival end of dislysate delivery line 4, the port of export of dislysate delivery line 4 is connected with peristaltic pump 5, and peristaltic pump 5 is connected with dialysis liquid bath 1 by conduit; Dialysis tubing 3 comprises permeability inner tube 7, dialysis membrane 8 and permeability outer tube 6, dialysis membrane 8 is wrapped in outside permeability inner tube 7 tube walls, permeability outer tube 6 is enclosed within permeability inner tube 7 peripheries, the arrival end of permeability inner tube 7 and the port of export are arranged at the same side in permeability outer tube 6, the arrival end of permeability inner tube 7 is connected with the port of export of dislysate ingress pipe 2, and the port of export of permeability inner tube 7 is connected with the arrival end of dislysate delivery line 4; Permeability inner tube 7 comprises straight tube and bend pipe, and straight tube and bend pipe connect as one, and bend pipe is looped around straight tube periphery in the shape of a spiral, and the tube wall of permeability inner tube 7 is that hollow out is latticed; The arrival end of permeability outer tube 6 relative permeability inner tubes 7 and the opposite side at port of export place are also provided with hard plastic stub bar, and the tube wall of permeability outer tube 6 is hollow out paliform; Haemodialysis equipment also comprises Y type snap close 9, one end of Y type snap close 9 is enclosed within permeability outer tube 6 peripheries, the two ends of bifurcated are enclosed within respectively the periphery of dislysate ingress pipe 2 and dislysate delivery line 4, and dislysate ingress pipe 2 is guided into the arrival end of permeability inner tube 7, dislysate delivery line 4 is guided into the port of export of permeability inner tube 7; On dislysate ingress pipe 2 and dislysate delivery line 4, be provided with snap close 13 and knob 12. On dislysate ingress pipe 2, be provided with dislysate flow speed control valve 10, dialysis liquid bath 1 is outside equipped with temperature regulating device.

Further, the material of outer tube 6 and inner tube 7 is polyureas amine ester; The material of dialysis membrane 8 is polyether sulfone; The diameter of inner tube 7 is 0.5 ~ 2mm, and length is 200 ~ 300mm; The diameter of described outer tube 6 is 3 ~ 5mm, and length is 150 ~ 300mm.

The using method of haemodialysis equipment of the present invention is: before patient is dialysed, first by puncture, dialysis tubing is inserted in human body in artery with seal wire or sheath pipe, then with Y type snap close 9, dislysate ingress pipe 2 and dislysate delivery line 4 are connected with permeability outer tube 6, and dislysate ingress pipe 2 is guided into the arrival end of permeability inner tube 7, dislysate delivery line 4 is guided into the port of export of permeability inner tube 7, connect other parts simultaneously, open peristaltic pump 5, in dialysis liquid bath 1, dislysate is inputted by dislysate ingress pipe 2 in the permeability inner tube 7 of dialysis tubing 3, in the permeability inner tube 7 of dialysis tubing 3, be now the dislysate of hyperosmosis, blood enters permeability outer tube 6, be outside permeability inner tube 7, to be the lower blood of osmotic pressure (containing great quantities of spare moisture), middle across dialysis membrane 8, 8 hydrones of allowing molecular weight of dialysis membrane pass through, most of macromolecule composition in blood can not pass through, excessive moisture in blood is sustainable like this infiltrates through in dislysate, leave blood, and along with dislysate delivery line 4 transfers out external, reach dialysis object, meanwhile in pipe, the dislysate of high concentration continues to upgrade by flowing, and keeps higher permeable pressure head, reaches and continues the effect of dialysing. in the time that needs stop dialysing, to close peristaltic pump 5, and Y type snap close 9 or snap close 13 folders are closed, Y type snap close 9 or snap close 13 are made up of flexible material, realize the temporary transient cutout of dislysate, if will separate completely, by the knob of spin dialysis liquid ingress pipe 2 and dislysate delivery line 4, auxiliary dislysate ingress pipe 2 and dislysate delivery line 4 separate with the permeability inner tube 7 of dialysis tubing 3, and disconnection dislysate ingress pipe 2 and dislysate delivery line 4 are connected with dialysis tubing 3.

Method dialysis tubing 3 being placed in human body artery in the present invention is prior art, and dislysate flow speed control valve 10 and temperature regulating device are also prior art, no longer describe in detail at this. After dislysate circulates for several times in equipment, osmotic pressure will reduce, and when water absorbing capacity drops to certain value, can abandon, and more renews penetrating fluid.

The present invention is not limited to aforesaid detailed description of the invention. The present invention expands to any new feature or any new combination disclosing in this manual, and the arbitrary new method disclosing or step or any new combination of process.

Claims

1. a haemodialysis equipment, comprise dialysis liquid bath, dislysate ingress pipe, dialysis tubing, dislysate delivery line and peristaltic pump, it is characterized in that, described dialysis liquid bath is connected with dislysate ingress pipe entrance point, the dislysate ingress pipe port of export is connected with dialysis tubing respectively with the arrival end of dislysate delivery line, the port of export of dislysate delivery line is connected with peristaltic pump, and peristaltic pump is connected with dialysis liquid bath by conduit; Described dialysis tubing comprises permeability inner tube, dialysis membrane and permeability outer tube, described dialysis membrane is wrapped in outside permeability inner pipe wall, described permeability outer tube sleeve is in permeability inner tube periphery, the arrival end of described permeability inner tube and the port of export are arranged at the same side in permeability outer tube, the arrival end of described permeability inner tube is connected with the port of export of dislysate ingress pipe, and the port of export of permeability inner tube is connected with the arrival end of dislysate delivery line; Described haemodialysis equipment also comprises Y type snap close, and one end of Y type snap close is enclosed within permeability outer tube periphery, and the two ends of bifurcated are enclosed within respectively the periphery of dislysate ingress pipe and dislysate delivery line.

2. haemodialysis equipment according to claim 1, is characterized in that, the arrival end of described permeability outer tube relative permeability inner tube and the opposite side at port of export place are also provided with hard plastic stub bar.

3. haemodialysis equipment according to claim 1, is characterized in that, on described dislysate ingress pipe, is provided with dislysate flow speed control valve.

4. haemodialysis equipment according to claim 1, is characterized in that, described dialysis liquid bath is outside equipped with temperature regulating device.

5. haemodialysis equipment according to claim 1, is characterized in that, described inner tube comprises straight tube and bend pipe, and straight tube and bend pipe connect as one, and bend pipe is looped around straight tube periphery in the shape of a spiral.

6. haemodialysis equipment according to claim 1, is characterized in that, the tube wall of described permeability outer tube is hollow out paliform, and the tube wall of described permeability inner tube is that hollow out is latticed, and the material of described inner and outer tubes is polyureas amine ester.

7. haemodialysis equipment according to claim 1, is characterized in that, on described dislysate ingress pipe and dislysate delivery line, is provided with snap close.

8. haemodialysis equipment according to claim 1, is characterized in that, on described dislysate ingress pipe and dislysate delivery line, is provided with knob.

9. according to the haemodialysis equipment described in the arbitrary claim of claim 1 to 8, it is characterized in that, the diameter of described permeability inner tube is 0.5 ~ 2mm, and pipe range is 200 ~ 300mm.

10. according to the haemodialysis equipment described in the arbitrary claim of claim 1 to 8, it is characterized in that, the diameter of described permeability outer tube is 3 ~ 5mm, and length is 150 ~ 300mm.