CN110604713A - Essence containing water shield extract and preparation method thereof - Google Patents
Essence containing water shield extract and preparation method thereof Download PDFInfo
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- CN110604713A CN110604713A CN201911041550.7A CN201911041550A CN110604713A CN 110604713 A CN110604713 A CN 110604713A CN 201911041550 A CN201911041550 A CN 201911041550A CN 110604713 A CN110604713 A CN 110604713A
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- CN
- China
- Prior art keywords
- extract
- water shield
- essence
- water
- hyaluronic acid
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
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- Biotechnology (AREA)
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- Microbiology (AREA)
- Mycology (AREA)
- Gerontology & Geriatric Medicine (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the technical field of cosmetics, and particularly relates to an essence containing a water shield extract and a preparation method thereof. The essence disclosed by the invention comprises the following components in percentage by mass: 5-15% of water shield extract, 2-5% of licorice extract, 1-2% of centella asiatica extract, 0.1-0.3% of turmeric extract, 1-5% of propylene glycol, 1-5% of butanediol, 0.1-0.5% of sodium lauryl sulfate, 0.1-0.5% of triethanolamine, 0.1-0.5% of hyaluronic acid, 0.2-1.0% of hydroxymethyl cellulose, 0.2-1.0% of glutathione, 0.05-0.3% of carbomer, 0.05-0.3% of allantoin, 0.05-0.3% of essence and the balance of deionized water. The essence disclosed by the invention can effectively inhibit activities of tyrosinase, collagenase, hyaluronidase, elastase and the like, and can effectively increase skin elasticity, tighten skin and delay skin aging.
Description
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to an essence containing a water shield extract and a preparation method thereof.
Background
Water shield (water shield, Brasenia schrebei), also known as hoof grass, lake vegetable, water sunflower or dew sunflower, grows in ponds, lakes and marshes, is a perennial freshwater aquatic herbaceous plant of the water shield genus of the Nymphaeaceae family, is fresh and tender, and is one of the precious vegetables.
The water shield has high nutritive value and medicinal value, contains rich acidic heteropolysaccharide which is an immunopotentiator, can enhance the immunity of organisms, prevents diseases and has strong inhibiting effect on a plurality of tumors, and is rich in zinc element which is 'zinc king' in plants, can promote the intelligence development of children and prevent and treat the hyperactivity of children.
At present, water shield is primarily processed to be prepared into canned food, which is sold to southeast Asia countries such as Japan, Korea and the like and is deeply favored by southeast Asia people. The tender buds and petioles of the water shield are wrapped with transparent colloid, the appearance is crystal clear, and the taste is smooth. The modern clinical pharmacological test shows that the water shield extract has the activity of inhibiting tyrosinase, elastase, collagenase, hyaluronidase and the like, and can be used for preparing cosmetics with high additional value.
Some patents relate to the application of water shield in cosmetics, but the formula is complex and the antioxidant effect is poor, and the antioxidant effect of the prepared cosmetics still needs to be further improved.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: the water shield extract-containing essence has a good antioxidant effect on skin.
The second purpose of the invention is to provide a preparation method of the water shield extract-containing essence.
The technical scheme adopted by the invention for solving the technical problems is as follows:
an essence containing a water shield extract comprises the following components in percentage by mass: 5-15% of water shield extract, 2-5% of licorice extract, 1-2% of centella asiatica extract, 0.1-0.3% of turmeric extract, 1-5% of propylene glycol, 1-5% of butanediol, 0.1-0.5% of sodium lauryl sulfate, 0.1-0.5% of triethanolamine, 0.1-0.5% of hyaluronic acid, 0.2-1.0% of hydroxymethyl cellulose, 0.2-1.0% of glutathione, 0.05-0.3% of carbomer, 0.05-0.3% of allantoin, 0.05-0.3% of essence and the balance of deionized water.
The essence containing the water shield extract consists of the following components in percentage by mass: 5-15% of water shield extract, 2-5% of licorice extract, 1-2% of centella asiatica extract, 0.1-0.3% of turmeric extract, 1-5% of propylene glycol, 1-5% of butanediol, 0.1-0.5% of sodium lauryl sulfate, 0.1-0.5% of triethanolamine, 0.1-0.5% of hyaluronic acid, 0.2-1.0% of hydroxymethyl cellulose, 0.2-1.0% of glutathione, 0.05-0.3% of carbomer, 0.05-0.3% of allantoin, 0.05-0.3% of essence and 60-80% of deionized water.
The above essence containing water shield extract can be used as facial mask essence.
The water shield extract is water shield extract.
The preparation method of the water shield extract-containing essence comprises the following steps: weighing water shield extract, licorice extract, centella extract, turmeric extract, propylene glycol, butanediol, sodium lauryl sulfate, triethanolamine, hyaluronic acid, hydroxymethyl cellulose, glutathione, carbomer, allantoin and essence according to the weight percentage, and then uniformly mixing with deionized water to obtain the water shield.
The water shield extract is prepared by a preparation method comprising the following steps:
1) washing water shield with cold water, soaking for 8-10 hr, soaking with 60-70 deg.C water for 2-4 hr, pulverizing, soaking with ethanol for 6-8 hr to obtain crude extract;
2) centrifuging the crude extract in the step 1), collecting filtrate, and removing ethanol in the filtrate to obtain the product.
The mass fraction of the ethanol in the step 1) is 65-75%.
In the step 1), the volume ratio of ethanol to (the mixture of water shield and water) for soaking is 1: 1.
Preferably, the licorice extract is an alcohol-water extract of licorice, contains active substances such as glycyrrhizic acid, and is provided by Jiangsu Huibo Biotech limited.
Preferably, the centella asiatica extract contains active substances such as asiaticoside and madecassoside, and is provided by Jiangsu Huibobo Biotech limited.
Preferably, the turmeric extract is an alcohol-water extract of turmeric, contains active substances such as curcumin, and is provided by Jiangsu Huibo Biotech Co.
The water shield can inhibit activity of collagenase, and with increasing of collagenase in skin layers, the generation amount of collagen cannot keep up with enzymolysis speed, so that the collagen in the skin is reduced, and the skin is aged and loses vitality. The water shield can inhibit activity of collagenase, and can reduce collagen attenuation, thereby delaying aging. Researches find that the water shield extract can inhibit the activity of collagen enzyme, inhibit the hydrolysis of collagen and effectively prevent skin aging and vitality loss.
Thirdly, the water shield extract has the function of inhibiting hyaluronidase. The hyaluronidase is a specific lyase of hyaluronic acid, and the hyaluronic acid has good moisturizing effect and is a good transdermal enhancer. Therefore, the hyaluronic acid can not only keep the normal physiological function of the hyaluronic acid without being decomposed by inhibiting the activity of the hyaluronic acid, but also achieve the effects of resisting inflammation, allergy and tumor, and simultaneously supplement the hyaluronic acid and achieve better moisturizing effect.
Finally, the water shield extract also has the effect of inhibiting the activity of elastase. Elastase is not produced any more with age, and when the in vivo elastase is over-expressed, the elastase is promoted to excessively decompose the elastin, so that wrinkles are produced, the skin gradually loses elasticity, and the skin aging is accelerated. The water shield extract can effectively inhibit the activity of elastase, and has the effects of increasing skin elasticity, tightening skin, delaying aging and the like.
Glycyrrhrizae radix is dried root and rhizome of Glycyrrhiza uralensis Fisch of Leguminosae. Has the effects of invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain, and harmonizing the medicines. Modern clinical pharmacology tests show that the licorice extract can inhibit the activity of tyrosinase and dopachrome tautomerase (TRP-2) and inhibit the polymerization of 5, 6-dihydroxyindole, so as to prevent the formation of melanin and achieve the effect of whitening skin.
Centella asiatica is a dry whole plant of centella asiatica of centella of Umbelliferae, has the effects of clearing heat, promoting diuresis, removing toxic substances and relieving swelling, and is clinically used for treating traumatic injury, skin diseases and the like. The main active molecules of centella asiatica include asiaticoside, asiatic acid and madecassoside, and can inhibit fibrous tissue hyperplasia, promote skin growth, and inhibit skin ulcer.
Turmeric, a perennial herb of the family zingiberaceae, has the effects of breaking blood, promoting the circulation of qi, stimulating the menstrual flow, relieving pain and the like. It is clinically used for treating chest and abdomen distending pain, shoulder and arm pain, irregular menstruation, amenorrhea, traumatic injury, etc. The main active molecules of the turmeric comprise curcumin, bisdemethoxycurcumin, demethoxycurcumin, dihydrocurcumin and the like, and the turmeric extract has the effects of maintaining beauty, keeping young, improving skin color and the like.
Hyaluronic acid, an acidic mucopolysaccharide compound, has various physiological effects in the human body, can regulate vascular wall permeability, promote wound healing, preserve moisture and water, diffuse water electrolyte, operate and the like. Hyaluronic acid is known as an ideal natural moisturizing factor, can improve the skin nutrient metabolism, make the skin tender and smooth, remove wrinkles, increase the elasticity and prevent aging, and is a good transdermal absorption enhancer while moisturizing.
The invention relates to a water shield extract-containing essence, which takes a water shield extract, a turmeric extract, a centella extract, a liquorice extract and hyaluronic acid as main components and assists auxiliary agents such as allantoin, glutathione and the like, wherein the glutathione is tripeptide containing gamma-amido bond and sulfhydryl, contains active sulfhydryl and can metabolize human cells to generate H2O2Reducing the glutathione into water, removing free radicals in human bodies, damaging cell membranes by the free radicals, promoting aging of the organisms, preventing the glutathione from peroxidation on human body cells, improving the oxidation resistance of the skin and enabling the skin to generate luster; allantoin is an amphoteric compound, can combine multiple substances to form double salt, has effects of protecting from light, sterilizing, relieving pain, resisting oxidation, keeping skin moisture, moistening and softening, enhancing skin care product hydrophilicity, absorbing water, and preventing water dispersion, and can promote tissueGrowth, cell metabolism, softening stratum corneum proteins; the essence disclosed by the invention can inhibit fibrous tissue hyperplasia and promote skin growth under the synergistic effect of the components, has the effect of inhibiting collagenase activity, and can further inhibit the activity of tyrosinase and dopachrome tautomerase (TRP-2) to further inhibit the polymerization of 5, 6-dihydroxyindole, so that the formation of melanin is prevented, and the effects of whitening skin, improving elasticity and firming skin, delaying skin aging and the like are further achieved. The essence disclosed by the invention has small irritation to skin and good affinity with skin, has the effects of whitening, elasticity and skin tightening of skin and skin aging delaying, and is healthy and environment-friendly.
Detailed Description
Example 1
The essence containing the water shield extract in the embodiment is composed of the following components in parts by mass:
5 parts of water shield extract, 5 parts of licorice extract, 1 part of centella extract, 0.3 part of turmeric extract, 5 parts of propylene glycol, 1 part of butanediol, 0.1 part of sodium lauryl sulfate, 0.1 part of triethanolamine, 0.35 part of hyaluronic acid, 1.0 part of hydroxymethyl cellulose, 1.0 part of glutathione, 0.05 part of carbomer, 0.05 part of allantoin, 0.05 part of essence and 80 parts of deionized water.
The preparation method of the water shield extract-containing essence comprises the following steps:
A. preparing water shield extracting solution
1) Washing fresh water shield with cold water, soaking for 10 hours, soaking with 70 ℃ water for 2 hours, then crushing to obtain a mixture of water shield and water, and then soaking with 65% ethanol for 8 hours to obtain a crude extract; wherein the ratio of the volume of 65% ethanol used to the volume of the above mixture is 1: 1;
2) centrifuging the crude extract in the step 1) at 10000rpm for 10min, collecting filtrate, and then removing ethanol in the filtrate in vacuum to obtain the product;
B. preparation of essence
The skin care cream is prepared by uniformly stirring and mixing 5 parts of water shield extract, 5 parts of licorice extract, 1 part of centella extract, 0.3 part of turmeric extract, 5 parts of propylene glycol, 1 part of butanediol, 0.1 part of sodium lauryl sulfate, 0.1 part of triethanolamine, 0.35 part of hyaluronic acid, 1.0 part of hydroxymethyl cellulose, 1.0 part of glutathione, 0.05 part of carbomer, 0.05 part of allantoin, 0.05 part of essence and 80 parts of deionized water.
Example 2
The essence containing the water shield extract in the embodiment is composed of the following components in parts by mass:
15 parts of water shield extract, 5 parts of licorice extract, 2 parts of centella extract, 0.1 part of turmeric extract, 1 part of propylene glycol, 5 parts of butanediol, 0.5 part of sodium lauryl sulfate, 0.5 part of triethanolamine, 0.5 part of hyaluronic acid, 0.2 part of hydroxymethyl cellulose, 0.2 part of glutathione, 0.3 part of carbomer, 0.3 part of allantoin, 0.3 part of essence and 69.1 parts of deionized water.
The preparation method of the water shield extract-containing essence comprises the following steps:
A. preparing water shield extracting solution
1) Washing fresh water shield with cold water, soaking for 8 hours, soaking with 60 deg.C water for 4 hours, pulverizing to obtain water shield and water mixture, and soaking with 75% ethanol for 6 hours to obtain crude extract; wherein the ratio of the volume of 75% ethanol used to the volume of the mixture is 1: 1;
2) centrifuging the crude extract in the step 1) at 10000rpm for 12min, collecting filtrate, and then removing ethanol in the filtrate in vacuum to obtain the product;
B. preparation of essence
The skin care cream is prepared by stirring and uniformly mixing 15 parts of water shield extract, 5 parts of licorice extract, 2 parts of centella extract, 0.1 part of turmeric extract, 1 part of propylene glycol, 5 parts of butanediol, 0.5 part of sodium lauryl sulfate, 0.5 part of triethanolamine, 0.5 part of hyaluronic acid, 0.2 part of hydroxymethyl cellulose, 0.2 part of glutathione, 0.3 part of carbomer, 0.3 part of allantoin, 0.3 part of essence and 69.1 parts of deionized water.
Example 3
The essence containing the water shield extract in the embodiment is composed of the following components in parts by mass:
10 parts of water shield extract, 3.5 parts of licorice extract, 1 part of centella extract, 0.2 part of turmeric extract, 3 parts of propylene glycol, 3 parts of butanediol, 0.2 part of lauryl sodium sulfate, 0.3 part of triethanolamine, 0.3 part of hyaluronic acid, 0.6 part of hydroxymethyl cellulose, 0.6 part of glutathione, 0.15 part of carbomer, 0.15 part of allantoin, 0.15 part of essence and 76.85 parts of deionized water.
The preparation method of the water shield extract-containing essence comprises the following steps:
A. preparing water shield extracting solution
1) Washing fresh water shield with cold water, soaking for 8 hours, soaking with 60 deg.C water for 4 hours, pulverizing to obtain water shield and water mixture, and soaking with 75% ethanol for 6 hours to obtain crude extract; wherein the ratio of the volume of 75% ethanol used to the volume of the mixture is 1: 1;
2) centrifuging the crude extract in the step 1) at 10000rpm for 12min, collecting filtrate, and then removing ethanol in the filtrate in vacuum to obtain the product;
B. preparation of essence
The skin care cream is prepared by uniformly stirring and mixing 10 parts of water shield extract, 3.5 parts of licorice extract, 1 part of centella extract, 0.2 part of turmeric extract, 3 parts of propylene glycol, 3 parts of butanediol, 0.2 part of lauryl sodium sulfate, 0.3 part of triethanolamine, 0.3 part of hyaluronic acid, 0.6 part of hydroxymethyl cellulose, 0.6 part of glutathione, 0.15 part of carbomer, 0.15 part of allantoin, 0.15 part of essence and 76.85 parts of deionized water.
Experimental example 1
The extracts of examples 1 to 3 containing water shield extracts were tested for their antioxidant properties, i.e. their DPPH radical scavenging activity.
The activity of scavenging DPPH free radicals is determined by the following method:
1, 1-diphenyl-2-trinitrophenylhydrazine (DPPH) (15.0mg, accurate to 0.1mg) is accurately weighed, placed in a 500mL volumetric flask, and the volume is determined to 500mL by absolute ethyl alcohol to obtain DPPH solution.
1) Precisely remove DPPH solution (2mL) from the above-described water shield-containing water shield of examples 1-3Placing the extract essence (2mL) in a test tube, mixing well, standing for 35min, taking corresponding solvent (ethanol 4mL) as control sample, and measuring absorbance A at 517nm with spectrophotometer1。
2) Precisely transferring the water shield extract-containing essence (2mL) and absolute ethanol (2mL) of examples 1-3 into test tubes, mixing, standing for 35min, and measuring absorbance A at 517nm with spectrophotometer using corresponding solvent (ethanol 4mL) as control2。
3) Accurately transferring DPPH solution (2mL) and anhydrous ethanol (2mL) into test tube, mixing well, standing for 35min, determining absorbance A at 517nm with corresponding solvent (ethanol 4mL) as control sample, respectively using spectrophotometer3。
Clearance rate Y ═ 1- (A)1-A2)/A3]×100％
And (3) comparison test: replacing the water shield extract-containing essence in the steps 1) to 3) with commercially available water shield essence and commercially available licorice essence in a commercially available water shield mask respectively, and obtaining DPPH free radical scavenging rate by adopting the same method. The specific data are shown in table 1, and it can be seen from table 1 that the antioxidant performance of the essence prepared by the embodiment of the invention is obviously superior to that of commercially available water shield masks and liquorice masks.
TABLE 1 data of antioxidant performance test of examples 1-3 and commercially available masks
| Sample name | Results of antioxidant Property experiments |
| Example 1 | 72.4％ |
| Example 2 | 96.2％ |
| Example 3 | 88.8％ |
| Commercially available water shield mask | 54.3％ |
| Commercially available licorice facial mask | 23.1％ |
Experimental example 2
Tyrosinase inhibitory Activity assay
1) Experimental group
Sample group, 2mL of the water shield extract-containing essence of examples 1 to 3 was added to a test tube, Phosphate Buffered Saline (PBS) having pH6.8 (1.8mL) and 0.03% L-tyrosine solution (2mL) were added, the mixture was stirred at 37 ℃ for 10min, aqueous tyrosinase solution (350units/mL, 0.2mL) was added, the mixture was incubated at 37 ℃ for 25min, and absorbance at 475nm (B) was measured with an ultraviolet-visible spectrophotometer.
Blank group, the procedure is the same as that of the sample group, and the L-tyrosine solution (B) is replaced by the phosphate buffer solution with the same volume0)。
And in the control group, the steps are the same as those of the sample group, deionized water with the same volume is used for replacing the essence containing the water shield extract, and the absorbance A at 475nm is measured by an ultraviolet-visible spectrophotometer.
The total blank group comprises the same steps as the sample group, the equal volume of deionized water is used for replacing the essence containing the water shield extract, the equal volume of phosphate buffer is used for replacing the L-tyrosine solution, and the absorbance A at 475nm is measured by an ultraviolet visible light spectrophotometer0。
Tyrosinase activity inhibition rate ═ 1- (B-B)0)/(A-A0)]×100％。
2) Comparison group: the serum in the commercially available water shield mask and the serum in the commercially available licorice mask are respectively adopted to replace the serum containing the water shield extract in the experimental group, and the tyrosinase activity inhibition rate is obtained by adopting the same method.
Table 2 inhibition ratio of tyrosinase activity by the essence, commercially available water shield mask solution and commercially available licorice mask solution in examples 1 to 3
| Sample name | Inhibition rate of tyrosinase activity |
| Example 1 | 42.1％ |
| Example 2 | 38.5％ |
| Example 3 | 40.2％ |
| Commercially available water shield mask | 12.6％ |
| Commercially available licorice facial mask | 9.8％ |
As is clear from the data in tables 1 and 2, the water shield extract-containing essence solutions in examples 1 to 3 of the present invention, which contain water shield extract, turmeric extract, centella asiatica extract, licorice extract, and hyaluronic acid as main components and auxiliary agents such as allantoin and glutathione, have significant advantages in terms of oxidation resistance and tyrosinase activity inhibition, as compared to commercially available water shield masks and commercially available licorice masks.
In light of the foregoing description of preferred embodiments in accordance with the invention, it is to be understood that numerous changes and modifications may be made by those skilled in the art without departing from the scope of the invention. The technical scope of the present invention is not limited to the contents of the specification, and must be determined according to the scope of the claims.
Claims (6)
1. The essence containing the water shield extract is characterized by comprising the following components in percentage by mass: 5-15% of water shield extract, 2-5% of licorice extract, 1-2% of centella asiatica extract, 0.1-0.3% of turmeric extract, 1-5% of propylene glycol, 1-5% of butanediol, 0.1-0.5% of sodium lauryl sulfate, 0.1-0.5% of triethanolamine, 0.1-0.5% of hyaluronic acid, 0.2-1.0% of hydroxymethyl cellulose, 0.2-1.0% of glutathione, 0.05-0.3% of carbomer, 0.05-0.3% of allantoin, 0.05-0.3% of essence and the balance of deionized water.
2. The brasenia schreberi extract-containing essence of claim 1, which is characterized by comprising the following components in percentage by mass: 5-15% of water shield extract, 2-5% of licorice extract, 1-2% of centella asiatica extract, 0.1-0.3% of turmeric extract, 1-5% of propylene glycol, 1-5% of butanediol, 0.1-0.5% of sodium lauryl sulfate, 0.1-0.5% of triethanolamine, 0.1-0.5% of hyaluronic acid, 0.2-1.0% of hydroxymethyl cellulose, 0.2-1.0% of glutathione, 0.05-0.3% of carbomer, 0.05-0.3% of allantoin, 0.05-0.3% of essence and 60-80% of deionized water.
3. The water shield extract-containing essence of claim 1, wherein the water shield extract is a water shield extract.
4. The method for preparing the water shield extract-containing essence of any one of claims 1 to 3, comprising the following steps: weighing water shield extract, licorice extract, centella extract, turmeric extract, propylene glycol, butanediol, sodium lauryl sulfate, triethanolamine, hyaluronic acid, hydroxymethyl cellulose, glutathione, carbomer, allantoin and essence according to the weight percentage, and then uniformly mixing with deionized water to obtain the water shield.
5. The method of claim 4, wherein the water shield extract is prepared by a method comprising the steps of:
1) washing water shield with cold water, soaking for 8-10 hr, soaking with 60-70 deg.C water for 2-4 hr, pulverizing, soaking with ethanol for 6-8 hr to obtain crude extract;
2) centrifuging the crude extract in the step 1), collecting filtrate, and removing ethanol in the filtrate to obtain the product.
6. The method according to claim 5, wherein the mass fraction of ethanol in step 1) is 65 to 75%.
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| CN116473898A (en) * | 2023-04-21 | 2023-07-25 | 允斌(上海)健康科技有限公司 | Moisturizing repair composition, preparation method and application thereof |
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