CN110464499B - Environment-friendly PRF film pressing guide plate system - Google Patents
Environment-friendly PRF film pressing guide plate system Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C13/00—Dental prostheses; Making same
- A61C13/0003—Making bridge-work, inlays, implants or the like
- A61C13/0004—Computer-assisted sizing or machining of dental prostheses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C13/00—Dental prostheses; Making same
- A61C13/0003—Making bridge-work, inlays, implants or the like
- A61C13/0006—Production methods
- A61C13/0019—Production methods using three dimensional printing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C13/00—Dental prostheses; Making same
- A61C13/08—Artificial teeth; Making same
- A61C13/087—Artificial resin teeth
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Abstract
本发明提供一种环保型PRF压膜导板系统,包括:3D打印机,其中,所述3D打印机包括设置在一端的第一扫描模块,设置在另一端的第二扫描模块,以及设置在中间部分的第一打印模块和第二打印模块;所述第一打印模块对牙骨缺牙部分的断面或形状进行扫描获取缺失牙齿三维造型数据,通过缺失牙齿三维造型函数F(a,b,c,d,E)进行存储及表达,所述第一扫描模块,确定缺失牙齿三维造型函数F(a,b,c,d,E)后,则通过计算确定PRF膜函数f(a,b,c,d,e),通过上述对缺失牙齿三维造型函数F(a,b,c,d,E)、PRF膜函数f(a,b,c,d,e)的确定,所述第一打印模块确定压膜导板造型函数G。
The present invention provides an environment-friendly PRF lamination guide system, comprising: a 3D printer, wherein the 3D printer includes a first scanning module arranged at one end, a second scanning module arranged at the other end, and a A first printing module and a second printing module; the first printing module scans the cross-section or shape of the toothless part of the bone to obtain the three-dimensional modeling data of the missing teeth, and uses the three-dimensional modeling function F(a,b,c,d of the missing teeth) , E) for storage and expression, the first scanning module, after determining the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth, the PRF membrane function f(a,b,c, d, e), through the above determination of the three-dimensional modeling function F(a,b,c,d,E) and the PRF film function f(a,b,c,d,e) of the missing teeth, the first printing module Determine the lamination guide shape function G.
Description
技术领域technical field
本发明涉及PRF材质模板技术领域,具体而言,涉及一种环保型PRF压膜导板系统。The invention relates to the technical field of PRF material templates, in particular to an environment-friendly PRF lamination guide plate system.
背景技术Background technique
对于缺牙的患者,牙齿缺乏无论是一颗,数颗或者整个牙弓,种植牙都可以作为患的主要选项,一般的种植牙手术程序为牙龈的切开手术,以便让医生看到牙槽骨的结构,接着在植牙部位的牙槽骨上钻孔,把种植体植入牙槽骨,再把基台和种植体连接,最后把牙修复体连接到基台上。上述种植牙手术的成功与否的决定性因素是:种植牙和牙槽骨,种植牙和其他牙齿,以及种植牙之间的准确对位。For patients with missing teeth, whether the lack of teeth is one, several or the entire dental arch, dental implants can be used as the main option. The general dental implant surgery procedure is an incision of the gums so that the doctor can see the socket. Bone structure, then drill holes in the alveolar bone at the implant site, insert the implant into the alveolar bone, connect the abutment to the implant, and finally connect the dental restoration to the abutment. The decisive factors for the success of the above implant surgery are: the implant and the alveolar bone, the implant and other teeth, and the accurate alignment between the implants.
再者,目前人工牙主要是由钛金属制成,其优点是机械强度高,但钛基人工牙存着生物活性差,弹性模量过高和金属离子析出等缺点,牙齿种植完成后,牙细胞活性难以维持,随着数字化和信息化技术的发展,口腔牙科种植领域已经不同程度地引进了大批高科技数字化设备,如放射线CBCT扫描、CT三维重建、计算机虚拟种植、口腔模型扫描、计算机辅助设计/辅助制造(CAD/CAM)等数字化技术的应用已在我国大中城市逐步普及,数字化技术有助于提高牙科种植的效率和质量。Furthermore, at present artificial teeth are mainly made of titanium metal, which has the advantage of high mechanical strength, but titanium-based artificial teeth have disadvantages such as poor biological activity, high elastic modulus and metal ion precipitation. Cell activity is difficult to maintain. With the development of digital and information technology, a large number of high-tech digital equipment has been introduced in the field of dental implantology to varying degrees, such as radiation CBCT scanning, CT 3D reconstruction, computer virtual implantation, oral model scanning, computer-aided The application of digital technologies such as design/aided manufacturing (CAD/CAM) has been gradually popularized in large and medium-sized cities in my country, and digital technologies can help improve the efficiency and quality of dental implants.
现有中国专利公开号CN109203450A,公开了一种适于3D打印的PEEK复合材料人工牙的制备方法,其通过数字化技术来对人工牙的三维造型进行设计,并将人工牙三维造型基台以下的牙根表面设计成网状开槽结构或蜂窝状孔洞结构,然后用含晶须的PEEK复合材料作为人工牙的3D打印材料,根据设计好的人工牙造型数据用专用3D打印机打印人工牙,最后再对此人工牙进行表面处理和涂附活性骨膏,由此得到一种性能优越的PEEK复合材料人工牙。The existing Chinese Patent Publication No. CN109203450A discloses a method for preparing a PEEK composite artificial tooth suitable for 3D printing. The surface of the tooth root is designed into a mesh-like slotted structure or a honeycomb-like hole structure, and then the PEEK composite material containing whiskers is used as the 3D printing material for the artificial tooth. The artificial tooth is surface-treated and coated with active bone paste, thereby obtaining a PEEK composite artificial tooth with superior performance.
但上述技术方案中仍为种植牙的技术方案,虽采用了3D打印技术,但在种植过程中,由于新加入复合材料,一方面牙细胞的活性难以维持,另一方面采用3D打印机打印人工牙,再对人工牙进行表面处理,其形状往往与最终的牙缺口形状不吻合。However, the above technical solutions are still technical solutions for dental implants. Although 3D printing technology is used, in the process of implantation, due to the newly added composite materials, on the one hand, the activity of dental cells is difficult to maintain, and on the other hand, 3D printers are used to print artificial teeth. , and then surface treatment of artificial teeth, its shape often does not match the final shape of the tooth gap.
发明内容SUMMARY OF THE INVENTION
本发明的目的在于提供一种环保型PRF压膜导板系统,以解决上述种植牙成型难的问题。The purpose of the present invention is to provide an environment-friendly PRF lamination guide plate system to solve the above-mentioned problem of difficulty in forming dental implants.
为实现上述目的,本发明提出一种环保型PRF压膜导板系统,包括:3D打印机,其中,In order to achieve the above purpose, the present invention proposes an environment-friendly PRF lamination guide system, including: a 3D printer, wherein,
所述3D打印机包括设置在一端的第一扫描模块,设置在另一端的第二扫描模块,以及设置在中间部分的第一打印模块和第二打印模块;The 3D printer includes a first scanning module arranged at one end, a second scanning module arranged at the other end, and a first printing module and a second printing module arranged at the middle part;
所述第一打印模块对牙骨缺牙部分的断面或形状进行扫描获取缺失牙齿三维造型数据,通过缺失牙齿三维造型函数F(a,b,c,d,E)进行存储及表达,所述第一扫描模块,确定缺失牙齿三维造型函数F(a,b,c,d,E)后,则通过计算确定PRF膜函数f(a,b,c,d,e),通过上述对缺失牙齿三维造型函数F(a,b,c,d,E)、PRF膜函数f(a,b,c,d,e)的确定,所述第一打印模块确定压膜导板造型函数G,The first printing module scans the cross-section or shape of the tooth-missing part of the tooth to obtain the three-dimensional modeling data of the missing teeth, and stores and expresses the missing tooth three-dimensional modeling function F(a, b, c, d, E). In the first scanning module, after determining the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth, the PRF film function f(a,b,c,d,e) is determined by calculation. Determination of the three-dimensional modeling function F(a,b,c,d,E) and the PRF film function f(a,b,c,d,e), the first printing module determines the lamination guide modeling function G,
其中,PRF膜函数f(a,b,c,d,e)确定压膜导板内侧壁的函数关系,缺失牙齿三维造型函数F(a,b,c,d,E)确定压膜导板的外侧壁的函数关系;Among them, the PRF membrane function f(a,b,c,d,e) determines the functional relationship of the inner wall of the lamination guide, and the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth determines the outer side of the lamination guide the functional relationship of the wall;
所述第一打印模块按照上述压膜导板造型函数G将导板材料熔融后,从设置在第一打印模块上的第一打印喷头进行打印,形成压膜导板;After the first printing module melts the guide plate material according to the above-mentioned lamination guide shape function G, it prints from the first printing nozzle disposed on the first printing module to form the lamination guide;
在对所述压膜导板内侧壁打磨完成后,所述第二打印模块将PRF材质通过设置在其上的第二打印喷头按照PRF膜函数f(a,b,c,d,e)注入压膜导板内,PRF膜成型;After grinding the inner side wall of the lamination guide plate, the second printing module injects the PRF material into the pressure according to the PRF film function f(a, b, c, d, e) through the second printing nozzle arranged on it. Inside the film guide, the PRF film is formed;
其中,在上述缺失牙齿三维造型函数F(a,b,c,d,E)中,a表示牙齿标号,其从自然数1-24,按照下排牙齿及上排牙齿确定的顺序确定,b表示牙齿位置信息,c表示牙齿缺失程度,其值设定区间在0.1-0.95,d表示扫描的横面层数,根据3D打印机设定的扫描清晰程度及数据处理的繁琐程度决定,扫描清晰度越高,则设定的d数值越大,E表示每个横面的三维数据,其通过设定基准点作为坐标原点,设定该横面最大直径的圆心处的上表面位置作为坐标原点,设定相应的x,y,z坐标,或者则设定为二维坐标系,设定该横面最大直径的圆心处位置作为坐标原点,确定x,y轴。Among them, in the above-mentioned three-dimensional modeling function F(a, b, c, d, E) of missing teeth, a represents the tooth label, which is determined from the natural number 1-24 in the order determined by the lower row of teeth and the upper row of teeth, and b represents Tooth position information, c represents the degree of tooth loss, and its value is set in the range of 0.1-0.95, and d represents the number of horizontal layers scanned, which is determined according to the scanning clarity set by the 3D printer and the cumbersome degree of data processing. The higher the value of d, the larger the value of d is. E represents the three-dimensional data of each transverse plane. By setting the reference point as the origin of coordinates, the position of the upper surface at the center of the maximum diameter of the transverse plane is set as the origin of coordinates. Set the corresponding x, y, z coordinates, or set it as a two-dimensional coordinate system, set the position of the center of the maximum diameter of the transverse plane as the coordinate origin, and determine the x and y axes.
进一步地,所述PRF膜函数f(a,b,c,d,e)中,a,b,c,d与F(a,b,c,d,E)中的参量一致,每个横面的三维数据,满足下式:Further, in the PRF film function f(a,b,c,d,e), a,b,c,d are consistent with the parameters in F(a,b,c,d,E), each horizontal The three-dimensional data of the surface satisfies the following formula:
E(X,Y)=e(x+x1,y+y1)(1)E(X,Y)=e(x+x1,y+y1)(1)
E(X,Y)表示缺失牙齿三维造型函数每横面的两个坐标对应数值;E(X,Y) represents the corresponding value of the two coordinates of each transverse plane of the three-dimensional modeling function of the missing tooth;
e(x,y)表示PRF膜函数每横面的两个坐标对应数值。e(x,y) represents the corresponding values of the two coordinates of each transverse plane of the PRF film function.
进一步地,在上述式(1)中,Further, in the above formula (1),
x1,y1表示牙齿三维造型函数每横面对PRF膜函数每横面的厚度增量,L表示在每个横面上对应的压膜导板的厚度值。x1, y1 represent the thickness increment of the three-dimensional modeling function of the tooth for each transverse surface of the PRF film function, and L represents the thickness value of the corresponding lamination guide plate on each transverse surface.
进一步地,所述厚度值L与牙齿缺失程度c相关,Further, the thickness value L is related to the degree of tooth loss c,
L=L0×c (3)L=L 0 ×c (3)
c表示牙齿缺失程度,其值设定区间在0.1-0.95,L0表示导板预设厚度,其值200um,根据不同位置的牙齿而定,牙齿缺失程度可以根据缺失部分占整个牙齿高度方向的比例而定,牙齿预设高度为1.5cm-2.5cm,缺失部分所占比例,确定牙齿缺失程度。c represents the degree of tooth loss, and its value is set in the range of 0.1-0.95. L 0 represents the preset thickness of the guide plate, and its value is 200um. It depends on the teeth in different positions. The degree of tooth loss can be determined according to the proportion of the missing part in the height direction of the entire tooth. However, the preset height of the teeth is 1.5cm-2.5cm, and the proportion of the missing part determines the degree of tooth loss.
进一步地,在所述压膜导板成型后,所述第二扫描模块对压膜导板的内侧壁进行扫描,形成压膜导板内侧壁函数f(a1,b1,c1,d1,e1),压膜导板内侧壁函数f(a1,b1,c1,d1,e1)与PRF膜函数f(a,b,c,d,e)进行比较,根据两者的差异进行打磨,使在同一坐标系下,压膜导板内侧壁每个横面的三维数值均小于或等于PRF膜函数的相应数值。Further, after the lamination guide plate is formed, the second scanning module scans the inner side wall of the lamination guide plate to form a function f(a1, b1, c1, d1, e1) of the inner side wall of the lamination guide plate, and the lamination guide plate is formed. The inner side wall function f(a1,b1,c1,d1,e1) of the guide plate is compared with the PRF film function f(a,b,c,d,e), and polished according to the difference between the two, so that under the same coordinate system, The three-dimensional value of each lateral surface of the inner sidewall of the lamination guide plate is less than or equal to the corresponding value of the PRF film function.
进一步地,在完成所述PRF膜成型后,所述第一打印模块重新获取压膜导板造型函数G,也为骨粉造型函数,Further, after completing the forming of the PRF film, the first printing module re-acquires the lamination guide shape function G, which is also the bone meal shape function,
所述第一打印模块按照上述程序在所述PRF膜成型后的表面注入骨粉凝胶,骨粉凝胶与压膜导板成型相同,在骨粉凝胶成型后,通过第一扫描模块进行扫描获取骨粉凝胶外形函数F(a1,b1,c1,d1,E1),与缺失牙齿三维造型函数F(a,b,c,d,E)进行比对,再通过打磨,达到与缺失牙齿三维造型函数F(a,b,c,d,E)相同的数据。The first printing module injects bone powder gel on the surface of the PRF film after forming according to the above procedure. The bone powder gel is formed in the same way as the lamination guide plate. The plastic shape function F(a1,b1,c1,d1,E1) is compared with the missing tooth three-dimensional modeling function F(a,b,c,d,E), and then polished to achieve the missing tooth three-dimensional modeling function F (a,b,c,d,E) same data.
进一步地,所述PRF膜的制作过程为:静脉抽血液,置于无抗凝血酶的无菌试管中;立即将试管以3000r/min离心10min;静置后,血液样本可分为3层,在位于底层的红细胞碎片和位于顶层的淡黄色澄清液体血小板血浆之间,取出中间层的淡黄色凝胶,即为富血小板纤维蛋白;弃上清,去除凝胶状物底部的红细胞部分,获得初级的PRF凝胶,再将其静置于干燥消毒的容器内10min,使其自然收缩并释放其内的血清,或用无菌纱布吸附血清,同时经挤压塑形制备出具有一定形态、弹性及韧性的富血小板纤维蛋白膜。Further, the manufacturing process of the PRF membrane is as follows: blood is drawn intravenously and placed in a sterile test tube without antithrombin; the test tube is immediately centrifuged at 3000r/min for 10min; after standing, the blood sample can be divided into 3 layers , between the red blood cell fragments at the bottom layer and the pale yellow clear liquid platelet plasma at the top layer, take out the pale yellow gel in the middle layer, which is platelet-rich fibrin; discard the supernatant and remove the red blood cell part at the bottom of the gel, Obtain the primary PRF gel, and then place it in a dry and sterilized container for 10 minutes to make it shrink naturally and release the serum in it, or use sterile gauze to absorb the serum, and at the same time, squeeze and shape to prepare a certain shape. , elastic and tough platelet-rich fibrin membrane.
进一步地,所述骨粉凝胶包括聚消旋乳酸、矿化胶原,质量为所述聚消旋乳酸质量的160%~200%;多孔羟基磷灰石,质量为所述聚消旋乳酸质量的35%~40%。Further, the bone meal gel includes polylactic acid and mineralized collagen, the mass of which is 160% to 200% of the mass of the polylactic acid; the mass of porous hydroxyapatite is the mass of the polylactic acid. 35% to 40%.
进一步地,所述第一打印喷头和第二打印喷头中心对齐,并且,在所述3D打印机的台板上设置横向的导轨以使得两个打印模块能够相对移动,其中,两个打印喷头的相对面分别为弧形面,在弧形面的中心设置感应传感器,以对两个打印模块的位置进行采集并校准,在两个打印模块的相对面还设置有感应条,分别感应各自的位置。Further, the center of the first printing nozzle and the second printing nozzle are aligned, and a lateral guide rail is arranged on the platen of the 3D printer to enable the two printing modules to move relative to each other, wherein the relative movement of the two printing nozzles is The surfaces are arc-shaped surfaces, and an induction sensor is arranged in the center of the arc-shaped surface to collect and calibrate the positions of the two printing modules. There are also induction bars on the opposite surfaces of the two printing modules to sense their respective positions.
进一步地,所述台板的两端分别设置第一支撑台和第二支撑台,两个支撑台上分别放置有第一扫描模块和第二扫描模块,分别对其起到支撑作用;在两个所述支撑台之间还设置有调节柱,在两个支撑台的相对侧分别设置有若干上下排列的具有一定深度的调节孔。Further, the two ends of the platen are respectively provided with a first support table and a second support table, and a first scanning module and a second scanning module are respectively placed on the two support tables to support them respectively; An adjustment column is also arranged between the two support platforms, and a plurality of adjustment holes with a certain depth arranged up and down are respectively arranged on the opposite sides of the two support platforms.
与现有技术相比,本发明的有益效果在于,本发明通过3D打印机对牙骨缺牙部分的形状进行扫描获取形状数据,采用三维重建技术模拟牙齿缺失部分的牙齿三维造型,然后根据骨粉厚度确定压膜导板三维造型,在打印过程中,首先打印压膜导板,再对压膜导板内侧进行扫描,将压膜导板内侧三维造型数据与牙齿三维造型进行对比,对压膜导板内侧进行打磨,之后采用打印机输出PRF压膜对牙齿进行打印,缺失牙齿部分成型,3D打印机根据压膜导板三维造型在成型的牙齿外周输出骨粉,对骨粉外周打磨,完成操作。Compared with the prior art, the beneficial effect of the present invention is that the present invention scans the shape of the tooth missing part of the tooth by a 3D printer to obtain shape data, and uses the three-dimensional reconstruction technology to simulate the three-dimensional shape of the tooth of the missing part of the tooth. Determine the 3D shape of the lamination guide. During the printing process, first print the lamination guide, then scan the inner side of the lamination guide, compare the 3D modeling data of the inner side of the lamination guide with the 3D shape of the teeth, and polish the inner side of the lamination guide. After that, the printer is used to output PRF lamination to print the teeth, and the missing teeth are formed. The 3D printer outputs bone powder on the periphery of the formed teeth according to the three-dimensional modeling of the lamination guide, and grinds the periphery of the bone powder to complete the operation.
尤其,本发明设置第一打印模块对牙骨缺牙部分的断面或形状进行扫描获取缺失牙齿三维造型数据,通过缺失牙齿三维造型函数F(a,b,c,d,E)进行存储及表达,所述第一扫描模块,确定缺失牙齿三维造型函数F(a,b,c,d,E)后,则通过计算确定PRF膜函数f(a,b,c,d,e),通过上述对缺失牙齿三维造型函数F(a,b,c,d,E)、PRF膜函数f(a,b,c,d,e)的确定,所述第一打印模块确定压膜导板造型函数G,在对所述压膜导板内侧壁打磨完成后,所述第二打印模块将PRF材质通过设置在其上的第二打印喷头按照PRF膜函数f(a,b,c,d,e)注入压膜导板内,PRF膜成型。因此,本发明采用整体的PRF膜进行牙齿修复,一方面能够维持压细胞的活性,对牙髓进行修复,另一方面通过3D成型的PRF膜及骨粉凝胶结构,能够提供屏障,起到支撑作用。并且,本发明通过3D成型技术,首先成型压膜导板,相当于形成模具,再通过压膜导板成型PRF膜,克服了单独PRF膜形体不稳定的缺陷,能够一次成型,并杜绝感染。In particular, the present invention sets the first printing module to scan the section or shape of the tooth-missing part of the tooth to obtain the three-dimensional modeling data of the missing tooth, and stores and expresses it through the three-dimensional modeling function F(a, b, c, d, E) of the missing tooth. , the first scanning module, after determining the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth, then determining the PRF membrane function f(a,b,c,d,e) by calculation, through the above For the determination of the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth and the PRF film function f(a,b,c,d,e), the first printing module determines the modeling function G of the lamination guide plate , after grinding the inner side wall of the lamination guide plate, the second printing module injects the PRF material through the second printing nozzle arranged on it according to the PRF film function f(a,b,c,d,e) Inside the lamination guide, the PRF film is formed. Therefore, the present invention uses an integral PRF membrane for tooth restoration. On the one hand, it can maintain the activity of pressing cells and repair the dental pulp. On the other hand, the 3D-shaped PRF membrane and bone powder gel structure can provide a barrier and support effect. In addition, the present invention uses 3D molding technology to form a lamination guide plate first, which is equivalent to forming a mold, and then forms a PRF film through the lamination guide plate, which overcomes the defect of unstable shape of a single PRF film, can be formed at one time, and prevents infection.
尤其,本发明压膜导板的材质为PE膜、PVC膜等无机材料,其熔点高于100℃,也可为高熔点的碳化硅、氮化硅、氧化铝等陶瓷材料,只需通过3D打印输出熔融浆料后能够成型即可。In particular, the material of the lamination guide plate of the present invention is inorganic materials such as PE film and PVC film, whose melting point is higher than 100°C, and can also be ceramic materials such as silicon carbide, silicon nitride, and aluminum oxide with a high melting point, which only needs to be 3D printed. After outputting the molten slurry, it can be molded.
尤其,本发明设置两组扫描模块和打印模块,分别对压膜导板、PRF膜先后进行成型,并通过导轨机构和定位调节结构,调节两个部分的对准精度,实现快速、精准的打印及成型。In particular, the present invention is provided with two sets of scanning modules and printing modules, which respectively shape the lamination guide plate and the PRF film successively, and adjust the alignment accuracy of the two parts through the guide rail mechanism and the positioning adjustment structure, so as to realize fast and accurate printing and printing. forming.
尤其,本发明在压膜导板成型后,第二扫描模块对压膜导板10的内侧壁进行扫描,形成压膜导板内侧壁函数f(a1,b1,c1,d1,e1),压膜导板内侧壁函数f(a1,b1,c1,d1,e1)与PRF膜函数f(a,b,c,d,e)进行比较,根据两者的差异进行打磨,使在同一坐标系下,压膜导板内侧壁每个横面的三维数值均小于或等于PRF膜函数的相应数值,以便能够充分填充PRF材质。In particular, in the present invention, after the lamination guide is formed, the second scanning module scans the inner side wall of the
附图说明Description of drawings
通过阅读下文优选实施方式的详细描述,各种其他的优点和益处对于本领域普通技术人员将变得清楚明了。附图仅用于示出优选实施方式的目的,而并不认为是对本发明的限制。而且在整个附图中,用相同的参考符号表示相同的部件。在附图中:Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are for the purpose of illustrating preferred embodiments only and are not to be considered limiting of the invention. Also, the same components are denoted by the same reference numerals throughout the drawings. In the attached image:
图1为本发明实施例的环保型PRF压膜导板系统的结构示意图;1 is a schematic structural diagram of an environment-friendly PRF lamination guide system according to an embodiment of the present invention;
图2为本发明实施例的压膜导板的成型结构示意图;FIG. 2 is a schematic diagram of a molding structure of a lamination guide according to an embodiment of the present invention;
图3为本发明实施例的PRF压膜牙齿的成型结构示意图。FIG. 3 is a schematic diagram of the molding structure of the PRF laminated tooth according to the embodiment of the present invention.
具体实施方式Detailed ways
下面参照附图来描述发明的优选实施方式。本领域技术人员应当理解的是,这些实施方式仅仅用于解释发明的技术原理,并非在限制发明的保护范围。Preferred embodiments of the invention are described below with reference to the accompanying drawings. It should be understood by those skilled in the art that these embodiments are only used to explain the technical principle of the invention, and are not intended to limit the protection scope of the invention.
需要说明的是,在发明的描述中,术语“上”、“下”、“左”、“右”、“内”、“外”等指示的方向或位置关系的术语是基于附图所示的方向或位置关系,这仅仅是为了便于描述,而不是指示或暗示所述装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对发明的限制。It should be noted that, in the description of the invention, the terms “upper”, “lower”, “left”, “right”, “inner”, “outer” and other terms indicated in the direction or the positional relationship are based on the terms shown in the accompanying drawings The direction or positional relationship is only for the convenience of description, rather than indicating or implying that the device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on the invention.
此外,还需要说明的是,在发明的描述中,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通。对于本领域技术人员而言,可根据具体情况理解上述术语在发明中的具体含义。In addition, it should be noted that, in the description of the invention, unless otherwise expressly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it may be a fixed connection or a Removable connection, or integral connection; can be mechanical connection, can also be electrical connection; can be directly connected, can also be indirectly connected through an intermediate medium, can be internal communication between two components. For those skilled in the art, the specific meanings of the above terms in the invention can be understood according to specific situations.
请参阅图1所示,其为本发明实施例的环保型PRF压膜导板系统的结构示意图,包括3D打印机1,通过3D打印机对牙骨缺牙部分的形状进行扫描获取形状数据,采用三维重建技术模拟牙齿缺失部分的牙齿三维造型,然后根据骨粉厚度确定压膜导板三维造型,在打印过程中,首先打印压膜导板,再对压膜导板内侧进行扫描,将压膜导板内侧三维造型数据与牙齿三维造型进行对比,对压膜导板内侧进行打磨,之后采用打印机输出PRF压膜对牙齿进行打印,缺失牙齿部分成型,3D打印机根据压膜导板三维造型在成型的牙齿外周输出骨粉,对骨粉外周打磨,完成操作。Please refer to FIG. 1 , which is a schematic structural diagram of an environment-friendly PRF lamination guide system according to an embodiment of the present invention, including a 3D printer 1. The 3D printer scans the shape of the missing teeth of the tooth to obtain shape data, and uses 3D reconstruction. The technology simulates the 3D shape of the missing tooth, and then determines the 3D shape of the lamination guide according to the thickness of the bone powder. During the printing process, the lamination guide is first printed, and then the inner side of the lamination guide is scanned, and the 3D shape data of the inner side of the lamination guide is compared with the 3D shape of the lamination guide. The three-dimensional modeling of the teeth was compared, the inner side of the lamination guide was polished, and then the PRF lamination was used to print the teeth, and the missing teeth were partially formed. Sand and finish.
具体而言,PRF(富血小板纤维蛋白膜)为凝胶状软体材质,直接通过3D打印不容易成型,通过压膜导板形成模具对PRF膜进行定性,再对PRF膜外周施加骨粉凝胶,即可对损伤牙齿、牙髓进行修复。Specifically, PRF (platelet-rich fibrin membrane) is a gel-like soft material, which is not easy to form directly by 3D printing. The PRF membrane is characterized by forming a mold with a lamination guide plate, and then bone powder gel is applied to the periphery of the PRF membrane, that is, Repair damaged teeth and pulp.
具体而言,本发明实施例的PRF膜的制作过程为:静脉抽血液,置于无抗凝血酶的无菌试管中;立即将试管以3000r/min离心10min;静置后,血液样本可分为3层,在位于底层的红细胞碎片和位于顶层的淡黄色澄清液体血小板血浆之间,取出中间层的淡黄色凝胶,即为富血小板纤维蛋白;弃上清,去除凝胶状物底部的红细胞部分,获得初级的PRF凝胶,再将其静置于干燥消毒的容器内10min,使其自然收缩并释放其内的血清,或用无菌纱布吸附血清,同时经挤压塑形制备出具有一定形态、弹性及韧性的富血小板纤维蛋白膜。Specifically, the manufacturing process of the PRF membrane in the embodiment of the present invention is as follows: blood is drawn intravenously and placed in a sterile test tube without antithrombin; the test tube is immediately centrifuged at 3000 r/min for 10 min; after standing, the blood sample can be Divided into 3 layers, between the red blood cell debris in the bottom layer and the pale yellow clear liquid platelet plasma in the top layer, take out the pale yellow gel in the middle layer, which is platelet-rich fibrin; discard the supernatant and remove the bottom of the gel The erythrocyte part, obtain the primary PRF gel, and then put it in a dry and sterile container for 10 minutes to naturally shrink and release the serum in it, or use sterile gauze to absorb the serum, and at the same time, it is prepared by extrusion molding. A platelet-rich fibrin membrane with certain shape, elasticity and toughness is produced.
具体而言,本发明实施例的骨粉凝胶包括聚消旋乳酸、矿化胶原,质量为所述聚消旋乳酸质量的160%~200%;多孔羟基磷灰石,质量为所述聚消旋乳酸质量的35%~40%。制作过程为:配制聚消旋乳酸溶液;将矿化胶原加到所述聚消旋乳酸溶液中混匀,再加入多孔羟基磷灰石混匀,得到混合液;将所述混合液灌入模具中;将所述模具冻干;将经所述冻干后得到的材料解析;将经解析后的材料粉碎;和将经粉碎后得到的颗粒筛分,得到PLA基牙科骨粉。此为常规制作方法,不再赘述。其中,聚消旋乳酸分子量优选为115000~85000,矿化胶原蛋白采用如下方法进行制备:取120~180mL冰醋酸加入反应釜中,倒入纯化水,使总体积达到3~6L,再加入3~8g的胶原蛋白海绵,开启搅拌。用纯化水将12~15g氯化钙溶解,经定量滤纸过滤流入200mL的容量瓶中,备用。称量一定质量的磷酸,使溶液中磷和氯化钙溶液中的钙的摩尔比为1~3:1。用适量纯化水将磷酸溶解,经定量滤纸过滤流入200mL的容量瓶中,备用。用400mL纯化水将10~30克氢氧化钠溶解,备用。将配好的氯化钙溶液300~800mL边搅拌边缓慢加入搅拌好的酸溶胶原液中,充分反应搅拌2~8小时。然后将配好的磷酸溶液250~500mL继续加入上述反应体系中,充分反应搅拌1~5小时。将配好的氢氧化钠液加入到反应体系中,测定pH值,直到pH值为6~8时停止滴加,将混合溶液继续搅拌5~24h,然后静止沉淀,并对沉淀进行清洗。将清洗后的沉淀进行冷冻干燥,得到矿化胶原。此为常用制作方法,此不再赘述。Specifically, the bone meal gel according to the embodiment of the present invention includes polyracemic lactic acid and mineralized collagen, the mass of which is 160% to 200% of the mass of the polyracemic lactic acid; porous hydroxyapatite, the mass of which is the 35% to 40% of the quality of the lactic acid. The production process is as follows: preparing a polyracemic lactic acid solution; adding mineralized collagen into the polyracemic lactic acid solution and mixing, and then adding porous hydroxyapatite and mixing to obtain a mixed solution; pouring the mixed solution into a mold lyophilize the mold; decompose the material obtained after the lyophilization; pulverize the decomposed material; and sieve the particles obtained after the pulverization to obtain a PLA-based dental bone powder. This is a conventional manufacturing method and will not be repeated here. Among them, the molecular weight of poly(lactic acid) is preferably 115000-85000, and the mineralized collagen is prepared by the following method: add 120-180 mL of glacial acetic acid into the reaction kettle, pour in purified water to make the total volume reach 3-6L, and then add 3 ~8g of collagen sponge with stirring turned on. Dissolve 12 to 15 g of calcium chloride with purified water, filter through quantitative filter paper, and flow into a 200 mL volumetric flask for later use. Weigh a certain mass of phosphoric acid so that the molar ratio of phosphorus in the solution to calcium in the calcium chloride solution is 1 to 3:1. Dissolve phosphoric acid with an appropriate amount of purified water, filter it through quantitative filter paper, and pour it into a 200 mL volumetric flask for later use. Dissolve 10 to 30 grams of sodium hydroxide with 400 mL of purified water for later use. 300-800 mL of the prepared calcium chloride solution is slowly added to the stirred acid-dissolved collagen solution while stirring, and the mixture is fully reacted and stirred for 2-8 hours. Then, 250-500 mL of the prepared phosphoric acid solution was continuously added into the above reaction system, and the reaction was fully stirred for 1-5 hours. Add the prepared sodium hydroxide solution into the reaction system, measure the pH value, stop the dropwise addition when the pH value is 6-8, continue stirring the mixed solution for 5-24 hours, and then settle for static precipitation, and wash the precipitation. The washed precipitate was freeze-dried to obtain mineralized collagen. This is a common production method, which will not be repeated here.
具体而言,压膜导板的材质为PE膜、PVC膜等无机材料,其熔点高于100℃,也可为高熔点的碳化硅、氮化硅、氧化铝等陶瓷材料,只需通过3D打印输出熔融浆料后能够成型即可。Specifically, the material of the lamination guide plate is inorganic materials such as PE film and PVC film, whose melting point is higher than 100 °C, and can also be ceramic materials such as silicon carbide, silicon nitride, and aluminum oxide with a high melting point. After outputting the molten slurry, it can be molded.
结合图1所示,本实施例的3D打印机包括设置在一端的第一扫描模块17,设置在另一端的第二扫描模块27,以及设置在中间部分的第一打印模块21和第二打印模块22。其中,所述第一扫描模块17,对待修复牙齿的断面或外形进行扫描,并生成牙齿缺失部分的缺失牙齿三维造型,也即牙齿缺失部分的三维造型,通过缺失牙齿三维造型函数F(a,b,c,d,E)进行存储及表达,其中,a表示牙齿标号,其从自然数1-24,按照下排牙齿及上排牙齿确定的顺序确定,b表示牙齿位置信息,具体位于口腔位置,方便对牙齿进行定位,c表示牙齿缺失程度,其值设定区间在0.1-0.95,由于牙齿缺失严重,需要修复体积较大,本实施例采用的主要成分为PRF膜,软体状,因此,根据缺失程度确定骨粉的厚度,d表示扫描的横面层数,根据3D打印机设定的扫描清晰程度及数据处理的繁琐程度决定,扫描清晰度越高,则设定的d数值越大,E表示每个横面的三维数据,其通过设定基准点作为坐标原点,如设定该横面最大直径的圆心处的上表面位置作为坐标原点,设定相应的x,y,z坐标,当然,也可不考虑横面的厚度,则设定为二维坐标系,设定该横面最大直径的圆心处位置作为坐标原点,确定x,y轴。1 , the 3D printer of this embodiment includes a
具体而言,所述第一扫描模块17,确定好缺失牙齿三维造型函数F(a,b,c,d,E)后,则通过计算确定PRF膜函数f(a,b,c,d,e),a,b,c,d与F(a,b,c,d,E)中的参量一致。其中,Specifically, the
E(X,Y)=e(x+x1,y+y1) (1)E(X,Y)=e(x+x1,y+y1) (1)
E(X,Y)表示缺失牙齿三维造型函数每横面的两个坐标对应数值;E(X,Y) represents the corresponding value of the two coordinates of each transverse plane of the three-dimensional modeling function of the missing tooth;
e(x,y)表示PRF膜函数每横面的两个坐标对应数值;e(x,y) represents the corresponding values of the two coordinates of each transverse plane of the PRF film function;
x1,y1表示牙齿三维造型函数每横面对PRF膜函数每横面的厚度增量,L表示在每个横面上对应的压膜导板的厚度值,结合图2所示。在本实施例中,厚度L与牙齿缺失程度c相关,x1, y1 represent the thickness increment of each transverse surface of the tooth three-dimensional modeling function to each transverse surface of the PRF film function, and L represents the thickness value of the corresponding lamination guide plate on each transverse surface, as shown in Figure 2. In this embodiment, the thickness L is related to the degree of tooth loss c,
L=L0×c (3)L=L 0 ×c (3)
在本实施例中,c表示牙齿缺失程度,其值设定区间在0.1-0.95,L0表示导板预设厚度,其值200um,根据不同位置的牙齿而定,牙齿缺失程度可以根据缺失部分占整个牙齿高度方向的比例而定,牙齿预设高度为1.5cm-2.5cm,缺失部分所占比例,确定牙齿缺失程度。In this embodiment, c represents the degree of tooth loss, and its value is set in the range of 0.1-0.95. L 0 represents the preset thickness of the guide plate, and its value is 200um. It depends on the teeth in different positions. The degree of tooth loss can be determined according to the proportion of the missing part. The proportion of the entire tooth height direction is determined. The preset height of the tooth is 1.5cm-2.5cm, and the proportion of the missing part determines the degree of tooth loss.
本发明实施例的导板厚度随着牙齿缺失程度的增加而增加,当需要修复较大体积的牙齿时,则导板厚度随着增加,起到很好的支撑作用,本实施例,在对PRF成型后,骨粉的厚度与导板厚度相同,相应的骨粉的厚度也会增加,以便提供整个修复后牙齿的强度。The thickness of the guide plate in the embodiment of the present invention increases with the increase of the degree of tooth loss. When a larger volume of teeth needs to be repaired, the thickness of the guide plate increases along with it, which plays a good supporting role. After that, the thickness of the bone powder is the same as the thickness of the guide plate, and the thickness of the corresponding bone powder is also increased in order to provide the strength of the whole restored tooth.
具体而言,通过上述对缺失牙齿三维造型函数F(a,b,c,d,E)、PRF膜函数f(a,b,c,d,e)的确定,最终确定压膜导板造型函数G,Specifically, through the above determination of the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth and the PRF membrane function f(a,b,c,d,e), the modeling function of the lamination guide plate is finally determined. G,
其中,PRF膜函数f(a,b,c,d,e)确定压膜导板内侧壁的函数关系,缺失牙齿三维造型函数F(a,b,c,d,E)确定压膜导板的外侧壁的函数关系。Among them, the PRF membrane function f(a,b,c,d,e) determines the functional relationship of the inner wall of the lamination guide, and the three-dimensional modeling function F(a,b,c,d,E) of the missing teeth determines the outer side of the lamination guide function of the wall.
结合图1所示,本实施例的第一打印模块21按照上述压膜导板造型函数G将导板材料熔融后,从设置在第一打印模块21上的第一打印喷头31进行打印,形成压膜导板10,也即PRF膜的成型模具。在压膜导板10成型后,第二扫描模块27对压膜导板10的内侧壁进行扫描,形成压膜导板内侧壁函数f(a1,b1,c1,d1,e1),压膜导板内侧壁函数f(a1,b1,c1,d1,e1)与PRF膜函数f(a,b,c,d,e)进行比较,根据两者的差异进行打磨,使在同一坐标系下,压膜导板内侧壁每个横面的三维数值均小于或等于PRF膜函数的相应数值,以便能够充分填充PRF材质。在对压膜导板内侧壁打磨完成后,所述第二打印模块22将PRF材质通过设置在其上的第二打印喷头32按照PRF膜函数f(a,b,c,d,e)注入压膜导板10内,PRF膜成型,将PRF膜取出备用。Referring to FIG. 1 , the
结合图1所示,在本实施例中,第一打印喷头21和第二打印喷头22中心对齐,并且,在3D打印机的台板13上设置横向的导轨16以使得两个打印模块能够相对移动。本实施例的两个打印喷头的相对面分别为弧形面,在弧形面的中心设置感应传感器221,以对两个打印模块的位置进行采集并校准,在两个打印模块的相对面还设置有感应条223,分别感应各自的位置,以便调整两个模块的相对位置。1 , in this embodiment, the center of the
结合图1所示,台板13的两端分别设置第一支撑台11和第二支撑台12,两个支撑台上分别放置有第一扫描模块17和第二扫描模块27,分别对其起到支撑作用。在两个支撑台之间还设置有调节柱14,在两个支撑台的相对侧分别设置有若干上下排列的调节孔15,调节孔15具有一定的深度,以便对调节柱的高度,以及通过移动两个支撑台调节相对位置。As shown in FIG. 1 , the two ends of the
结合图1所示,本实施例的第一扫描模块17和第二扫描模块27均能够横向移动,采用CBCT断层扫描技术,其中,第一扫描模块17穿入第一横轴18中,并可沿第一横轴横向移动,并且,第一横轴的自由端设置有一凸台,其能够对第一扫描模块进行限位;相应的,第二扫描模块27穿入第二横轴28中,并可沿第二横轴横向移动级定位。在本实施例中,第一扫描模块17、第二扫描模块27之间通信,通过有线或者无线的方式进行通信,交互数据。同理,第一打印模块和第二打印模块之间通信,通过有线或者无线的方式进行通信,交互数据。With reference to FIG. 1 , both the
具体而言,在完成PRF膜成型后,第一打印模块21重新获取压膜导板造型函数G,也为骨粉造型函数。Specifically, after the PRF film is formed, the
第一打印模块21按照上述程序在PRF膜成型后的表面注入骨粉凝胶,骨粉凝胶与压膜导板成型相同,在骨粉凝胶成型后,通过第一扫描模块进行扫描获取骨粉凝胶外形函数F(a1,b1,c1,d1,E1),与缺失牙齿三维造型函数F(a,b,c,d,E)进行比对,再通过打磨,达到与缺失牙齿三维造型函数F(a,b,c,d,E)相同的数据即可。将制作完成的PRF膜与骨粉凝胶的牙齿在原有牙齿上修复即可。The
尽杆已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, Alternatives and modifications, the scope of the invention is defined by the appended claims and their equivalents.
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