CN110200664A - Sampler, preservation container, sampling component and the method that cervical cell samples certainly - Google Patents

Abstract

The present invention relates to a kind of for the sampler of sampling certainly of cervical cell, preservation container, sampling component and the method for sampling.The sampler includes: tubular shell, and sampling opening is configured at the lower end of the tubular shell；And thief rod, the thief rod extends in the tubular shell in parallel with the tubular shell, the lower end of the thief rod is provided with sampling head, the sampling head is in the initial state in the tubular shell, the thief rod is configured to move along the axial direction of the tubular shell, enables the sampling head to pass through the sampling and is open and reaches except the tubular shell；Wherein, the lower end surface of the sampling head is configured to obtain the sampling surface of sample, and when the sampler is inserted into the receiving hole for saving container, the lower end surface of the sampling head can be in contact with the sample collection portion at the bottom for being located at the receiving hole.Sampling certainly for cervical cell can be conveniently realized by this sampler.

Description

Sampler, storage container, sampling component and method for self-sampling of cervical cells

technical field

The invention relates to the technical field of cervical sampling, in particular to a sampler for self-sampling in the cervix. The invention also relates to a storage container used in conjunction with the sampler. The present invention also relates to a sampling assembly comprising the above-mentioned sampler and a storage container. The present invention also relates to a method for collecting samples using the above-mentioned sampler and storage container.

Background technique

Cervical cell sampling is a preliminary step for detecting whether the sampled person suffers from diseases such as cervical infection.

The current cervical cell collection is usually done by professionals such as doctors and nurses in professional places such as hospitals and medical stations. However, this method of operation is likely to make the sampled person feel uncomfortable. Some sampled people even refused to be tested because they did not want to be overexposed to outsiders. Or some sampled people may not be able to go to the hospital for cell collection because their residence is far away from the hospital or their own physical reasons. For these sampled persons, a hospital sampler is usually given to them for sampling at home by themselves or by relatives (this is referred to in the art as "self-sampling"). The collected samples are then sent to the hospital for relevant testing.

However, there are currently no cervical cell sampling devices specifically designed for self-sampling. The sampler used in the hospital is difficult to use proficiently and inconveniently for the samplers without special training (especially the self-samplers with low education level). Problems such as sampling failure or sample contamination often occur due to incorrect use methods or irregular use methods. In this case, not only the detection effect will be inaccurate, but also resources will be wasted. In addition, in hospitals, the cell samples collected by the sampler will be directly placed in the preservation solution for preservation and subsequent detection. However, for self-collection that is not carried out in the hospital, placing the cell sample in the preservation solution and then sending it to the hospital for testing is prone to problems such as insufficient sample elution, difficult transportation, liquid leakage, and contamination. These problems will also bring great inconvenience to the collection and preservation of samples.

Therefore, there is a need for a sampling device that can conveniently realize self-sampling of cervical cells.

Contents of the invention

In view of the above problems, the present invention proposes a sampler, through which the self-sampling of cervical cells can be conveniently realized. The present invention also proposes a storage container matched with the above-mentioned sampler. The present invention also proposes a sampling assembly comprising the above-mentioned sampler and a storage container. The invention also proposes a sampling method for self-sampling of cervical cells.

According to a first aspect of the present invention, a sampler for self-sampling of cervical cells is proposed, the sampler comprising: a cylindrical housing with a sampling opening configured at the lower end of the cylindrical housing; and a sampling rod, the sampling rod is parallel to the cylindrical housing and extends inside the cylindrical housing, a sampling head is provided at the lower end of the sampling rod, and the sampling head is in the cylindrical shape in the initial state In the housing, the sampling rod is configured to move along the axial direction of the cylindrical housing, so that the sampling head can pass through the sampling opening and protrude out of the cylindrical housing; wherein , the lower end face of the sampling head is configured as a sampling surface for obtaining samples, and when the sampler is inserted into the holding hole of the storage container, the lower end face of the sampling head can be positioned at the bottom of the holding hole contact with the sample collection part.

The user can insert the sampler into the vagina, and take a sample by extending the sampling head to touch the cervix. The sampling surface of the sampling head is configured at the lower end face. When in use, the lower end surface will be at the forefront of the entire sampling head. By contacting the cervix through the lower end surface, samples of cervical cells can be effectively collected. After taking the sampler out of the vagina, the user can directly insert the sampler into the receiving hole of the storage container. Since the sampling head is extended at this time, its lower end surface can conveniently contact the sample collection part at the bottom of the holding hole. The user can apply the cervical cell sample on the sample collection part by rotating, pressing and other methods. During this process, the side wall of the receiving hole can limit the movement range of the sampler, thereby effectively avoiding failure or inaccurate sample coating. Therefore, even users who have not received professional training can use the sampler to conveniently collect cervical cells.

In one embodiment, an external thread is configured on the outer wall of the cylindrical housing, and the external thread matches an internal thread configured on the inner wall of the receiving hole of the storage container. Under the cooperation of the thread and the internal thread, the sampler can be rotated and inserted into the holding hole of the storage container, so that the lower end surface of the sampling head can be against the bottom of the holding hole. The sample collection portion rotates relative to the sample collection portion.

In one embodiment, the sampling head is configured as a truncated cone, and the larger bottom surface of the truncated cone forms the lower end surface of the sampling head; and/or the sampling head is an elastic sampling head, so The elastic sampling head is configured to be compressively deformable along the axial direction of the sampling head.

In one embodiment, an operation hole is opened on the side wall of the cylindrical casing, the operation hole extends along the axial direction of the cylindrical casing, and a control protrusion is connected to the sampling rod. The control protrusion extends from the sampling rod through the operation hole and extends out of the cylindrical housing, and the control protrusion is configured to be able to move along the operation hole in the operation hole. The axial direction of the cylindrical housing moves, thereby driving the sampling rod to move along the axial direction of the cylindrical housing.

In one embodiment, one or more positioning holes communicating with the operation hole and extending transversely relative to the operation hole are also configured on the cylindrical housing, and the manipulation protrusion can be positioned along the transverse direction. Move into the positioning hole, when the control protrusion is in the positioning hole, the positioning hole restricts the control protrusion so that the control protrusion cannot move along the axial direction of the cylindrical housing. direction to move.

In one embodiment, the upper end of the sampling rod extends upwards and out from the upper end of the cylindrical housing, and a locking ring protrudes outside the sampling rod, and a diameter is formed in the cylindrical housing. A fixing plate extending inward, the fixing plate is closer to the sampling outlet than the locking ring, and an elastic member is arranged between the locking ring and the fixing plate.

According to the second aspect of the present invention, a storage container is proposed, the storage container includes a container main body, and an accommodation hole extending along the longitudinal direction to the upper end surface of the container main body is opened in the container main body. A sample collection part is configured at the bottom of the holding hole, and when a sampler for self-sampling of cervical cells is inserted into the holding hole, the sampling head of the sampler is configured such that the lower end surface of the sampling surface can be in contact with The sample collection parts are in contact.

In one embodiment, an internal thread is configured on the inner side wall of the accommodating hole, and the internal thread is matched with an external thread configured on the outer wall of the cylindrical housing of the sampler, and the internal thread and the Under the cooperation of the external thread, the sampler can be rotated and inserted into the holding hole of the storage container, so that the lower end surface of the sampling head of the sampler can be against the bottom of the holding hole. The sample collection part rotates relative to the sample collection part.

In one embodiment, the container body includes a cylindrical portion forming a side wall of the holding hole, and a bottom plate disposed under the cylindrical portion and forming a bottom wall of the holding hole, and the sample The collecting part is arranged on the bottom plate, and the cylindrical part and the bottom plate are detachably connected together to form the container main body.

According to a third aspect of the present invention, a sampling assembly for self-sampling of cervical cells is proposed, the sampling assembly includes: a sampler, and the sampler includes: a cylindrical housing, in which The lower end of the sampling rod is configured with a sampling opening and a sampling rod. The sampling rod extends in the cylindrical housing parallel to the cylindrical housing. A sampling head is arranged at the lower end of the sampling rod. The sampling head In the initial state within the cylindrical housing, the sampling rod is configured to move along the axial direction of the cylindrical housing so that the sampling head can protrude through the sampling opening to the In addition to the cylindrical housing, wherein the lower end surface of the sampling head is configured as a sampling surface for obtaining samples; The direction extends to the accommodation hole at the upper end surface of the container main body, and a sample collection part is configured at the bottom of the accommodation hole. When the sampler is inserted into the accommodation hole, the sampling head of the sampler The configuration is such that the lower end surface of the sampling surface can be in contact with the sample collection part.

According to a fourth aspect of the present invention, a sampling method for self-sampling of cervical cells is proposed, said method comprising the following steps: extending the sampling head of the sampler to perform sampling; inserting the sampler after sampling into the holding hole of the storage container, so that the lower end surface of the sampling head configured as a sampling surface is in contact with the sample collection portion at the bottom of the holding hole; and the lower end surface of the sampling head is rotated relative to the sample collection portion , to coat the sample on the lower end surface onto the sample collection part.

In one embodiment, an external thread is configured on the outer wall of the cylindrical housing of the sampler, and an internal thread matching the external thread is configured on the inner wall of the accommodating hole of the storage container, Rotate the sampler, under the cooperation of the internal thread and the external thread, insert the sampler into the receiving hole until the lower end surface of the sampling head is in contact with the sample collection part, The sampler is further rotated so that the lower end surface of the sampling head rotates against the sample collection part, so that the sample on the lower end surface is coated on the sample collection part.

Compared with the prior art, the present invention has the advantage that the user can insert the sampler into the vagina, and make the sampling head protrude to touch the cervix for sampling. The sampling surface of the sampling head is configured at the lower end face. When in use, the lower end surface will be at the forefront of the entire sampling head. By contacting the cervix through the lower end surface, samples of cervical cells can be effectively collected. After taking the sampler out of the vagina, the user can directly insert the sampler into the receiving hole of the storage container. Since the sampling head is extended at this time, its lower end surface can conveniently contact the sample collection part at the bottom of the holding hole. The user can apply the cervical cell sample on the sample collection part by rotating, pressing and other methods. During this process, the side wall of the receiving hole can limit the movement range of the sampler, thereby effectively avoiding failure or inaccurate sample coating. Therefore, even users who have not received professional training can use the sampler to conveniently collect cervical cells. The design of the operation hole and the positioning hole and their cooperation with the control projection allow the user to push out the sampling head step by step. This can prevent the sampling head from overextending and hurting the sampled person, and can also effectively relieve the psychological pressure of the user and the sampled person.

Description of drawings

Hereinafter, the present invention will be described in more detail with reference to the accompanying drawings. in:

Figure 1 shows a cross-sectional view of a sampler in a sampling assembly according to one embodiment of the present invention;

Figure 2 shows a schematic diagram of a sampler in a sampling assembly according to one embodiment of the present invention;

Figure 3 shows a sectional view of a holding container in a sampling assembly according to an embodiment of the present invention;

Fig. 4 shows a cross-sectional view of a holding container in a sampling assembly according to another embodiment of the present invention.

In the figures, the same parts are given the same reference numerals. The figures are not drawn to scale.

Detailed ways

The present invention will be further described below in conjunction with accompanying drawing.

The sampling assembly of the present invention may include the following sampler 100 and storage container 200 for self-sampling of cervical cell samples.

Figures 1-2 illustrate one embodiment of a sampler 100 according to the present invention.

As shown in FIG. 1 , the sampler 100 includes a cylindrical housing 110 , which can be configured as a hollow cylinder. A sampling opening is configured at the lower end of the cylindrical housing 110 . The sampler 100 also includes a sampling rod 120 disposed within the cylindrical housing 110 . The longitudinal axis of the sampling rod 120 is parallel to or overlaps with the longitudinal axis of the cylindrical housing 110 . A sampling head 122 is configured at the lower end of the sampling rod 120 for contacting the cervix to collect samples of cervical cells. In the initial state, the sampling head 122 is in the cylindrical casing 110 as shown in FIG. 1 , surrounded and protected. In use, the sampling rod 120 is movable along the longitudinal axis of the cylindrical housing 110 so that the sampling head 122 protrudes from the sampling opening at the lower end of the cylindrical housing 110 for sampling.

In a preferred embodiment, the sampling head 122 has a trapezoidal cross-section as shown in FIG. 1 . That is to say, the sampling head 122 can be configured in the shape of a conical frustum. The larger bottom surface of the truncated cone forms the lower end surface 122A of the sampling head 122 . The lower end surface 122A is formed as a sampling surface for contacting the cervix to collect cervical cells. Adopting this type of sampling head 122 here makes the sampling surface a flat surface with a large area. This is conducive to increasing the contact area between the sampling surface and the cervix, so that users who have not received professional training can collect enough samples without excessive operations (for example, stirring the sampler, etc.), thereby On the one hand, it can ensure the accuracy and effectiveness of the test results, and on the other hand, it can also avoid the injury of the sampled person. In addition, the sampling head 122 of this shape enables its sampling surface to contact the sample collection part 203 in the storage container 200 (described in detail below) with a relatively uniform force, so as to ensure that the sample can be evenly and effectively applied to the sample. On the collecting part 203.

Preferably, bristles 123 are provided at the lower end surface 122A of the sampling head 122, so as to capture and hold cervical cells at the lower end surface 122A.

In a preferred embodiment, the sampling head 122 is flexible, for example made of medical cotton. In this case, when the sampling head 122 is in contact with the cervix, the cervix can be prevented from being damaged. In addition, it is also beneficial to smear the sample on the sampling head 122 onto the sample collecting part 203 . In addition, in a preferred embodiment, the sampling head 122 has flexibility and limited elasticity. Therefore, after a sampling process is completed (especially after the sample on the lower end surface 122A is applied to the sample collection part 203 of the storage container 200), the sampling head 122 will be obviously deformed and cannot be used any more. The user can easily tell whether the sampling head 122 has been used, and the sampling head 122 can no longer be used. This sampling head 122 (or even the entire sampler 100) is disposable, which can effectively avoid problems such as pollution caused by repeated use.

In the embodiment shown in FIG. 1 , a locking ring 121 protruding radially outward is formed on the sampling rod 120 . In addition, a fixing plate 111 extending radially inward is configured inside the cylindrical housing 110 . The fixing plate 111 is located on the lower side of the locking ring 121 (that is, closer to the sampling opening), and an elastic member (such as a coil spring) 130 is disposed between them. This configuration allows the sampling rod 120 and the sampling head 122 to remain in place under normal conditions (ie, the sampling head 122 is within the cylindrical housing 110).

The upper end 120A of the sampling rod 120 extends upwards and out from the upper end of the cylindrical housing 110 . In this case, the user can push the upper end 120A of the sampling rod 120 to make the sampling head 122 protrude from the sampling opening. Preferably, a scale is provided at the upper end 120A, so that the user and the person to be sampled can grasp the protruding length of the sampling head 122 . This can effectively relieve the psychological pressure of users and sampled people. In particular, the 120A scale at the upper end is easy to read, which is very suitable for the sampled person to operate and read by himself.

In a preferred embodiment, a control protrusion 124 is provided at the side portion of the sampling rod 120 in the cylindrical housing 110, and the manipulation protrusion 124 extends through the opening on the side wall of the cylindrical housing 110. The operating hole 110A extends outside the cylindrical housing 110 so as to be touched and manipulated by the user's hand. As shown in FIG. 1 , the operation hole 110A is a long and narrow hole extending in the axial direction of the cylindrical housing 110 . Thus, the user can move the control protrusion 124 along the operation hole 110A, so that the sampling rod 120 and the sampling head 122 can move along the axial direction of the cylindrical housing 110 together, so that the sampling head 122 reach out. The user can dial the control protrusion 124 and read the scale on the upper end 120A of the sampling rod 120 . This arrangement can effectively prevent the scale from being blocked by the user's limbs.

In addition, as shown in FIG. 2 , one or more positioning holes 110B communicating with the operation hole 110A and extending laterally relative to the operation hole 110A are also configured on the cylindrical housing 110 . The manipulation protrusion 124 can enter into each positioning hole 110B, and be locked in the axial direction of the cylindrical housing 110 . The respective positioning holes 110B are spaced apart from each other in the axial direction of the cylindrical housing 110 to define a plurality of different gear positions. These gear positions respectively define different lengths of the sampling head 122 protruding from the sampling opening.

For example, at the beginning, the control protrusion 124 can be located in the positioning hole of the uppermost "0 gear" shown in FIG. 2 . At this time, the sampling head 122 is inside the cylindrical housing 110 and is restricted so as not to protrude. This can effectively prevent the sampler 110 from being misoperated. When using the sampler 110 , the user can manually push the manipulation projection 124 into the operation hole 110A, and push the manipulation projection 124 downward to make the sampling head 122 stretch out. When the control projection 124 moves to the position opposite to the positioning hole 110B of the "1st gear", the user can dial the control projection 124 into the positioning hole 110B of the "1st gear", and let the person being sampled feel whether the sampling head is has touched the cervix. If the cervix has been touched, it means that the sample has been successfully sampled, and the entire sampler 100 can be taken out. If there is no contact with the cervix, the control projection 124 can be dialed into the operation hole 110A again, and the control projection 124 can be moved downward to locate in the positioning holes 110B such as "2nd gear" and "3rd gear", so that the sampled The person again feels whether the sampling head has touched the cervix.

This structure and operation mode are very helpful for the user and the sampled person to grasp the current situation, and can greatly relieve the psychological pressure of the user and the sampled person. In addition, the sampling rod 120 and the sampling head 122 can also be rotated by turning the control protrusion 124 laterally at the positioning hole 110B. On the one hand, this rotation is beneficial for the subject to accurately feel the position of the sampling head 122 in the body. On the other hand, when the sampling head 122 touches the cervix, the lower end surface 122A of the sampling head 122 can rotate slightly at the cervix, so as to collect cervical cell samples more conveniently and effectively.

In addition, preferably, as shown in FIG. 1 and FIG. 2 , a blocking piece 140 extending radially outward is provided on the outer wall of the cylindrical housing 110 . The extending direction of the blocking piece 140 is substantially perpendicular to the extending direction of the longitudinal axis of the cylindrical housing 110 . When in use, the user can insert the sampler 100 into the vagina of the person to be sampled until the blocking piece 140 touches the body of the person to be sampled. Then, the sampling head 122 is extended again. The setting of the baffle 140 can ensure that the sampler 100 is inserted to an appropriate depth, thereby avoiding injury to the sampled person due to the deep insertion of the sampler 100, and also avoiding sampling failure due to the shallow insertion of the sampler 100.

Fig. 3 schematically shows an embodiment of a storage container 200 according to the present invention.

The storage container 200 includes a container body 201 . The container body 201 can, for example, be configured cylindrically or cuboidally. An accommodating hole is opened in the container main body 201 , and the accommodating hole extends to the upper end surface of the container main body 201 to form an opening. A sample collection part 203 is provided at the bottom of the receiving hole. The above-mentioned sampler 100 can be inserted into the receiving hole through the opening. At this time, the lower end surface 122A of the sampling head 122 can be in contact with the sample collection part 203 , so that the cervical cell sample on the lower end surface 122A is transferred to the sample collection part 203 . Here, the user can smear the sample on the sample collection part 203 more effectively by pressing, rotating the sampler 100 and other operations. The sidewall of the receiving hole forms the guide surface of the sampler 100 , thereby limiting the movable range of the sampler 100 . For example, the sampler 100 cannot be translated in the receiving hole. Therefore, problems such as "painting the wrong position" and "painting out of the circle" will not occur, ensuring that the collected samples can be effectively used in the detection.

Preferably, the upper end of the container body 201 extends upward to form a cover 204 . The cover body 204 is hinged to the container body 201 . In the storage state, or after the sample is collected on the sample collection part 203, the cover 204 can be turned down so that the receiving hole is covered to prevent the sample from being polluted. Instructions for use can also be printed on the surface of the cover 204 facing the receiving hole, so that when the cover 204 is erected relative to the container body 201, the user can easily see the use of the sampler 100 and the storage container 200 Way. When the cover body 204 covers the opening of the receiving hole on the container body 201 , the cover body 204 and the container body 201 may be connected together by, for example, a buckle connection.

In a preferred embodiment, an internal thread 202 is configured on the inner wall of the receiving hole of the container body 201; correspondingly, a matching external thread 112 is configured on the outer wall of the cylindrical housing 110 of the sampler 100 . Thus, the user can insert the sampler 100 into the receiving hole of the container body 201 by rotating the sampler 100 . This is beneficial to ensure that the lower end surface 122A of the sampling head 122 is aligned with the sample collection part 203, avoiding the failure of sample collection due to hand shaking, wrong force, and the like. After the sampler 100 is inserted into the bottom of the receiving hole so that the lower end surface 122A of the sampling head 122 is in contact with the sample collection part 203, the user can further rotate the sampler 100 (for example, turn 3-5 circles), so that the sampling head 122 The lower end surface 122A abuts against the sample collection part 203 more closely and rotates relative to the sample collection part 203 . Therefore, it is more beneficial to guide users who have not received professional training to collect samples on the sample collection part 203 .

In the embodiment shown in FIG. 4, the container main body is divided into two parts, that is, a cylindrical portion 201A for forming the side wall of the receiving hole, and a cylindrical portion 201A for forming the receiving hole provided under the cylindrical portion 201A. The bottom wall of the hole is the bottom plate 201B. The sample collecting part 203 is provided on the bottom plate 201B. The cylindrical portion 201A and the bottom plate 201B can be detachably joined together, for example, by a snap connection, to form a container main body. After the sample collection is completed and the storage container 200 is transported to a hospital or a test center, the sample collection part 203 can be easily obtained by detaching the cylindrical part 201A and the bottom plate 201B. The sample collection part 203 can be removed from the bottom plate 201B and used for detection directly.

The sample collection unit 203 here may be, for example, an FTA card, an FTA filter membrane, filter paper, or the like.

According to the present invention, a sampling method for realizing self-sampling of cervical cells is as follows.

First, the user holds the sampler 100 and inserts it into the vagina of the person to be sampled. In the case where the baffle 140 is provided, the user can insert the sampler 100 into the vagina of the person to be sampled until the baffle 140 is in contact with the body of the person to be sampled.

Then, the sampling head 122A is stretched out by turning the control protrusion 124 to move in the operation hole 110A. Sampling is performed by bringing the sampling head 122A to a corresponding depth (for example, to the positioning hole 110B of each gear).

After sampling, the sampler 100 is taken out from the body of the person to be sampled, and inserted into the receiving hole of the storage container 200 . In the case where the above-mentioned internal thread and external thread are provided, the sampler 100 can be conveniently inserted into the storage container 200 by rotating it.

After the lower end surface 122A of the sampling head 122 touches the sample collection part 203 , the sample can be applied to the sample collection part 203 by, for example, pressing down or rotating. In the case that the above-mentioned internal thread and external thread are provided, the lower end surface 122A of the sampling head 122 can be rotated against the sample collection part 203 by continuing to rotate (for example, 3-5 turns) the sampler 100, thereby The sample is applied to the sample collection part 203 .

Through the above-mentioned sampling assembly (including the sampler 100 and the storage container 200 ) and the sampling method, the user can conveniently collect the samples of the cervical cells of the sampled people. Even if the user is not highly educated or has weak hands-on ability, the collection, collection and preservation of samples can be effectively realized. Thus, it can be effectively ensured that the sample of cervical cells obtained from sampling can obtain accurate and effective results during detection.

It should be understood that "cervical cells" herein refers to "cervical exfoliated cells".

While the invention has been described with reference to a preferred embodiment, various modifications may be made and equivalents may be substituted for parts thereof without departing from the scope of the invention. In particular, as long as there is no structural conflict, the technical features mentioned in the various embodiments can be combined in any manner. The present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.

Claims (10)

1. a kind of sampler from sampling for cervical cell, the sampler include:

Tubular shell is configured with sampling opening at the lower end of the tubular shell；And

Thief rod, the thief rod extends in the tubular shell in parallel with the tubular shell, in the thief rod Lower end is provided with sampling head, and the sampling head is in the initial state in the tubular shell, and the thief rod is configured to It is moved along the axial direction of the tubular shell, enables the sampling head to pass through the sampling and be open and reach the cylinder Except shape shell；

Wherein, the lower end surface of the sampling head is configured to obtain the sampling surface of sample, is inserted into guarantor in the sampler When depositing in the receiving hole of container, the lower end surface of the sampling head can be with the sample collection portion phase at the bottom of the receiving hole Contact.

2. sampler according to claim 1, which is characterized in that be configured with outer spiral shell on the lateral wall of the tubular shell Line, the external screw thread match with the internal screw thread on the inner sidewall for being configured in the receiving hole for saving container,

Under the cooperation of the external screw thread and the internal screw thread, the sampler, which is able to rotate, is inserted into the appearance for saving container Receive in hole, enable the sampling head lower end surface be pressed against positioned at the receiving hole bottom at the sample collection portion and phase The sample collection portion is rotated.

3. sampler according to claim 1 or 2, which is characterized in that the sampling head is configured to round truncated cone shape, the circle The biggish bottom surface of truncated cone shape constitutes the lower end surface of the sampling head；And/or

The sampling head is flexible sampling head, and the flexibility sampling head is configured to compress along the axial direction of the sampling head Deformation.

4. according to claim 1 to sampler described in any one of 3, which is characterized in that on the side wall of the tubular shell Handle hole is offered, the handle hole extends along the axial direction of the tubular shell,

Manipulation protrusion is connected on the thief rod, the manipulation protrusion extends through the handle hole from the thief rod And extend to except the tubular shell, the manipulation protrusion is configured in the handle hole along the tubular shell Axial direction is mobile, and the thief rod is thus driven to move along the axial direction of the tubular shell.

5. sampler according to claim 4, which is characterized in that be also configured on the tubular shell and the operation Hole is connected and relative to one or more location hole that the handle hole is laterally extended,

The manipulation protrusion can be moved to the positioning hole in transverse direction, when the manipulation protrusion is in the positioning hole When, the location hole limits the manipulation protrusion and the manipulation protrusion cannot be moved along the axial direction of the tubular shell It is dynamic.

6. a kind of preservation container, the preservation container includes container body, offered in the container body along longitudinal side To the receiving hole for the upper end surface for extending to the container body, it is configured with sample collection portion at the bottom of the receiving hole, When the sampler from sampling for cervical cell is inserted into the receiving hole, the construction of the sampling head of the sampler is The lower end surface on sampling surface can be in contact with the sample collection portion.

7. preservation container according to claim 6, which is characterized in that be configured with interior spiral shell on the inner sidewall of the receiving hole Line, the internal screw thread match with the external screw thread on the lateral wall for the tubular shell for being configured in sampler,

Under the internal screw thread and the externally threaded cooperation, the sampler, which is able to rotate, is inserted into the appearance for saving container It receives in hole, the sample that the lower end surface of the sampling head of the sampler is pressed against at the bottom of the receiving hole is received Collection portion and relative to the sample collection portion rotate.

8. a kind of sampling component from sampling for cervical cell, the sampling component include:

Sampler, the sampler include:

Tubular shell is configured with sampling opening at the lower end of the tubular shell, and

Thief rod, the thief rod extends in the tubular shell in parallel with the tubular shell, in the thief rod Lower end is provided with sampling head, and the sampling head is in the initial state in the tubular shell, and the thief rod is configured to It is moved along the axial direction of the tubular shell, enables the sampling head to pass through the sampling and be open and reach the cylinder Except shape shell,

Wherein, the lower end surface of the sampling head is configured to obtain the sampling surface of sample；And

Container is saved, the preservation container includes container body, offers in the container body and extends in a longitudinal direction To the receiving hole of the upper end surface of the container body, it is configured with sample collection portion at the bottom of the receiving hole,

Wherein, when the sampler is inserted into the receiving hole, the construction of the sampling head of the sampler is sampling surface Lower end surface can be in contact with the sample collection portion.

9. a kind of method of sampling from sampling for cervical cell, the described method comprises the following steps:

The sampling head of sampler is stretched out, and is sampled；

Sampler after sampling is inserted into the receiving hole for saving container, so that the construction of the sampling head is sampling surface Lower end surface is in contact with the sample collection portion at the bottom of receiving hole；

It rotates the lower end surface of the sampling head relative to the sample collection portion, the sample on the lower end surface is coated to In the sample collection portion.

10. the method for sampling according to claim 9, which is characterized in that in the lateral wall of the tubular shell of the sampler On be configured with external screw thread, it is described save container receiving hole inner sidewall on be configured with the interior spiral shell to match with the external screw thread Line,

The sampler is rotated, under the internal screw thread and the externally threaded cooperation, the sampler is made to be inserted into the appearance It receives in hole, until the lower end surface of the sampling head is in contact with the sample collection portion,

The sampler is further rotated, so that the lower end surface of the sampling head rotates against the sample collection portion, with Sample on the lower end surface is coated in the sample collection portion.