CN221903784U - Cervical sampler, kit thereof and self-operable cervical cancer cell sampler - Google Patents

Abstract

The application discloses a cervical sampler, a kit thereof and a self-operable cervical cancer cell sampler, wherein the sampler comprises a shell, a first opening is formed in the shell, and the first opening is arranged close to the shell; the sampling brush is configured to be received in the housing and to expose at least a portion of the sampling brush to a location of the first notch in at least one use condition; the shaft comprises a shaft far end and a shaft near end, the shaft far end is connected with the sampling brush, the shaft near end further comprises an operator, the operator drives the shaft and the sampling brush to circumferentially rotate under the operation of external force, the sampling brush is enabled to contact with a target sample near the first notch in a use state, and friction force is generated to acquire biological tissues. The sampler facilitates placement at a target location and facilitates retrieval of sample tissue. The collected biological tissue can be cervical cells and can be used for screening cervical cancer.

Description

Cervical sampler and kit thereof and self-operable cervical cancer cell sampler

Technical Field

The utility model relates to the technical field of cervical medical products, in particular to a cervical sampler and a kit thereof and a self-operable cervical cancer cell sampler.

Background Art

In the prior art, cervical sampling products are inconvenient to use. Sample collection requires special medical facilities, the sample collection experience is poor, samples are easily contaminated, and the collected samples are difficult to collect very conveniently.

Utility Model Content

In view of this, the technical problem to be solved by the utility model is to provide a new cervical sampler to solve the problems that the existing cervical sampler has poor practical experience and is difficult to collect samples.

The utility model solves the above technical problems and provides a cervical sampler in one aspect, comprising:

The shell comprises a shell side wall and a closed shell distal wall, the shell side wall comprises a first notch, and the first notch is arranged near the shell distal wall; the sampling brush is configured to be accommodated in the shell and in at least one use state, at least a portion of the sampling brush is exposed to the position where the first notch is located; the shaft comprises a shaft distal end and a shaft proximal end, the shaft distal end is connected to the sampling brush, and the shaft proximal end also comprises an operator, the operator drives the shaft and the sampling brush to rotate circumferentially under external force operation, so that the sampling brush contacts the target sample near the first notch in the use state and generates friction to obtain biological tissue.

Another aspect of the present application provides an operating method of a cervical sampler, comprising:

A sampler according to any of the aforementioned embodiments is provided, wherein the retaining wall is set to a first use state; at least a portion of the sampler is placed at a target sample position; under the action of an external force, the retaining wall is set to a second use state, so that the sampling brush is exposed to the position where the first notch is located; under the action of the external force, the operator is rotated at least one circle, so that the operator drives the shaft and the sampling brush to rotate circumferentially, and the sampling brush contacts the target sample near the first notch and generates friction to obtain biological tissue.

Another aspect of the present application provides a cervical sampler kit, comprising:

The sampler of any of the preceding embodiments;

A container is configured and sized to accommodate at least the sampling brush therein.

Another aspect of the present application provides a self-operable cervical cancer cell sampler, comprising:

A shaft, including a distal end and a proximal end of the shaft; a sampling brush, used to obtain samples; an operator that can rotate in a circumferential direction, the outer wall of which is provided with anti-slip grooves, when the operator rotates under the action of an external force, the operator drives the shaft and the sampling brush to rotate in the same direction; a shell, including a shell side wall and a closed shell distal wall, the shell side wall includes a first notch, the first notch is arranged near the shell distal wall; the shell side wall is configured to include a second notch, the position of the second notch corresponds to the position of the operator, so that at least a part of the operator is exposed to the position where the second notch is located; an auxiliary plate, fixedly connected to the shell; a retaining wall, slidably connected to the auxiliary plate, so that the retaining wall can achieve axial movement relative to the shell; the size and shape of the retaining wall are configured to at least cover the first notch, and the retaining wall is configured to be in a first use state under the action of an external force. and switch between a first and a second use state; the retaining wall is configured to further include a window, the position of the window corresponds to the operator; wherein the sampling brush is configured to be accommodated in the housing and in at least one use state, at least a portion of the sampling brush is exposed to the position where the first notch is located; in the first use state, the retaining wall covers the first notch; in the second use state, the retaining wall is away from the first notch, so that the sampling brush is exposed to the position where the first notch is located; and at least a portion of the operator is exposed from the window; wherein the distal end of the shaft is connected to the sampling brush, and the proximal end of the shaft is connected to the operator; wherein the operator drives the shaft and the sampling brush to rotate 5 circumferential circles under external force operation, so that the sampling brush contacts the target sample near the first notch in the use state and generates friction to obtain cervical cells.

Other example embodiments are discussed herein.

The utility model has many advantages. In some embodiments, the sampler provided by the utility model has the characteristic of being easily pushed into the target position of the vagina and cervix; in some embodiments, the sampler provided by the utility model has the advantage of being easier and more accurate to obtain samples than a sampling brush; in some embodiments, the sampler provided by the utility model has the characteristic of being easier to push forward or pull back; in some embodiments, the sampler provided by the utility model adopts an ergonomic design, has the advantages of easier sample collection and easy operation, and is suitable for self-service operation by the sampled person without the need for additional medical training. In some embodiments, the biological tissue collected by the sampling device provided by the utility model is cervical cells, especially including PAP/HPV Co-Testing for cervical smear (PAP) and human papillomavirus (HPV), which is used for cervical cancer screening. The cervical sampler of the present application is suitable for use in medical places, and is also suitable for self-service use by the sampled person in non-medical places such as residences (such as residences), making the sample collection process more flexible and protecting the privacy and user experience of the sampled person. The cervical sampler of the present application makes it easier to obtain only the required cervical cells during the sampling process, while avoiding obtaining other tissues or mucus, avoiding impure or contaminated samples, and making the screening results of cervical cancer more accurate.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG1 is an exploded schematic diagram of a cervical sampler structure according to an embodiment of the utility model;

FIG2 is a schematic diagram of the embodiment shown in FIG1 in a first use state;

FIG3 is a schematic diagram of the embodiment shown in FIG1 in a second use state;

FIG. 4 is a schematic diagram of a partial structure of a sampling brush according to one embodiment.

DETAILED DESCRIPTION

In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention clearer and more understandable, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

In the utility model, the relative positions and directions of the upper, lower, top, bottom, inside and outside of the container are defined by taking the state in which the cervical sampler is placed during normal use as a reference state.

In the present invention, the "housing" is at least a part of the outermost structure of the sampler, which is used to protect the contents and provide a rigid appearance for the sampler.

In the present invention, "axial direction" refers to the direction where the axis of the cylinder where the shell is located is located, with the shell as a reference. In this application, the axial direction or the sampler axial direction refers to the same direction.

In the present application, "circumferential direction" refers to the circumferential direction of the cylinder where the outer shell is located, with the outer shell as a reference.

In the present application, "proximal end and distal end" are used as a reference to the state of the sampler when in use, the end close to the operator's hand is the proximal end, and the end relatively far from the operator's hand is the distal end.

The cervical sampler of the present application can also be used for vaginal biological tissue sampling.

In the present invention, “comprising” means including the following elements, but does not exclude other elements.

One aspect of the present application provides a cervical sampler, comprising:

The shell includes a shell side wall and a closed shell distal wall, the shell side wall includes a first notch, and the first notch is arranged near the shell distal wall; the sampling brush is configured to be accommodated in the shell and in at least one use state, at least a portion of the sampling brush is exposed to the position where the first notch is located; the shaft includes a shaft distal end and a shaft proximal end, the shaft distal end is connected to the sampling brush, and the shaft proximal end also includes an operator, the operator drives the shaft and the sampling brush to rotate circumferentially under external force operation, so that the sampling brush contacts the target sample near the first notch in the use state and generates friction to obtain biological tissue. The closed shell distal wall makes it easier for the sampler to move forward in the vagina under the action of thrust, and the sampling brush is also blocked during the process of moving into the vagina, which will not hinder the movement, so the use experience of the sampling brush is better.

In at least one embodiment, the sampler further includes a retaining wall, the size and shape of which are configured to cover at least the first notch, and the retaining wall is configured to switch between a first use state and a second use state under the action of an external force; in the first use state, the retaining wall covers the first notch; in the second use state, the retaining wall is away from the first notch, so that the sampling brush is exposed to the position where the first notch is located. The sampling brush is exposed only after the sampler reaches the target position of the cervix, so that the sample collected by it is more accurate.

In at least one embodiment, the retaining wall of the sampler is configured to move axially along the side wall of the housing.

In at least one embodiment, the retaining wall of the sampler is configured to slide circumferentially along the side wall of the housing.

In at least one embodiment, the retaining wall of the sampler is configured to further include a protrusion, and when the protrusion is operated by an external force, the retaining wall is switched between the first use state and the second use state.

In at least one embodiment, the operator of the sampler is a rotary converter, and the outer wall of the rotary converter is provided with anti-slip grooves. When the rotary converter rotates under the action of external force, the operator drives the shaft to make the sampling brush rotate in the same direction. In one embodiment, the rotary converter is a dial-type rotary converter.

In at least one embodiment, the side wall of the sampler's shell is configured to include a second notch, the position of the second notch corresponds to the position of the operator, so that at least a portion of the operator is exposed at the position of the second notch; the retaining wall is configured to also include a window, and when the retaining wall is in the second usage state, the position of the window corresponds to the operator, so that at least a portion of the operator is exposed.

In at least one embodiment, a booster wing is further provided at the proximal end of the retaining wall of the sampler, for applying an axial thrust or pull to the retaining wall through the booster wing to achieve switching between the first use state and the second use state.

In at least one embodiment, a base is further provided at the proximal end of the housing of the sampler, and one side of the base is rotatably connected to the proximal end of the shaft.

In at least one embodiment, the other side of the base of the sampler is configured to include a handle, and the handle is used to apply an axial pushing force or pulling force to the sampler so that the sampler can be inserted into or pulled out of the vagina.

In at least one embodiment, the distal wall of the sampler housing is generally dome-shaped.

In at least one embodiment, the sampling brush of the sampler is detachably connected to the distal end of the shaft. After the sampler completes sample collection, the entire sampling brush is removed and placed in a sample collection container, making sample acquisition very fast and easy.

In at least one embodiment, the sampler further includes an auxiliary plate, which is fixedly connected to the outer shell; the auxiliary plate is slidably connected to the retaining wall, so that the retaining wall can achieve axial movement relative to the outer shell.

In at least one embodiment, the biological tissue collected by the sampler is cervical cells. The cervical cells are particularly used for cervical smear (PAP) and human papillomavirus (HPV) dual testing (PAP/HPV Co-Testing) for cervical cancer screening.

Another aspect of the present application provides an operating method of a cervical sampler, comprising:

A sampler according to any of the aforementioned embodiments is provided, wherein the retaining wall is set to a first use state; at least a portion of the sampler is placed at a target sample position; under the action of an external force, the retaining wall is set to a second use state, so that the sampling brush is exposed to the position where the first notch is located; under the action of the external force, the operator is rotated at least one circle, so that the operator drives the shaft and the sampling brush to rotate circumferentially, and the sampling brush contacts the target sample near the first notch and generates friction to obtain biological tissue.

In at least one embodiment, the operation method further includes: setting the retaining wall to the first use state again, dragging the handle to pull the sampler out of the vagina; setting the retaining wall to the second use state again, exposing the sampling brush from the first notch, and removing the sampling brush from the distal end of the shaft to obtain the collected biological tissue. In at least one embodiment, the operator rotates at least 5 times to collect cervical cells.

Another aspect of the present application provides a cervical sampler kit, comprising:

The sampler of any of the preceding embodiments;

A container is configured and sized to accommodate at least the sampling brush therein.

In at least one embodiment, the kit further includes auxiliary tools, which are any one or more of lubricants, tweezers, and biological tissue preservation solutions. In one embodiment, the lubricant is applied to the distal wall of the housing to facilitate the sampler to be pushed into the target position in the vagina; the biological tissue preservation solution is pre-placed in the container; and tweezers are used to assist in disassembling the sampling brush including the sample and placing it in the container.

Another aspect of the present application provides a self-operable cervical cancer cell sampler, which includes: a shaft, including a distal end and a proximal end of the shaft; a sampling brush for obtaining samples; an operator that can rotate circumferentially, and the outer wall is provided with anti-slip grooves, when the operator rotates under the action of an external force, the operator drives the shaft and the sampling brush to achieve the same direction of rotation; a shell, including a shell side wall and a closed shell distal wall, the shell side wall includes a first notch, and the first notch is arranged near the shell distal wall; the shell side wall is configured to include a second notch, the position of the second notch corresponds to the position of the operator, so that at least a part of the operator is exposed to the position where the second notch is located; an auxiliary plate, fixedly connected to the shell; a retaining wall, slidably connected to the auxiliary plate, so that the retaining wall can achieve axial movement relative to the shell; the size and shape of the retaining wall are configured to at least cover the first notch, and the retaining wall It is configured to switch between a first use state and a second use state under the action of an external force; the retaining wall is configured to also include a window, and the position of the window corresponds to the operator; wherein the sampling brush is configured to be accommodated in the housing and in at least one use state, at least a portion of the sampling brush is exposed to the position where the first notch is located; in the first use state, the retaining wall covers the first notch; in the second use state, the retaining wall is away from the first notch, so that the sampling brush is exposed to the position where the first notch is located; and at least a portion of the operator is exposed from the window; wherein the distal end of the shaft is connected to the sampling brush, and the proximal end of the shaft is connected to the operator; wherein the operator drives the shaft and the sampling brush to rotate 5 times in a circumferential direction under the operation of an external force, so that the sampling brush contacts the target sample near the first notch in the use state and generates friction to obtain cervical cells.

The following further describes various aspects of the utility model in conjunction with the accompanying drawings:

FIG1 is a schematic diagram of an exploded structure of an exemplary cervical sampler 100; wherein the cervical sampler 100 includes a shell 1, a retaining wall 2, a shaft 10, a sampling brush 5, a base 30, a handle 13, and an auxiliary plate 8; wherein the shell 1 includes a shell side wall 26 and a closed shell distal wall 25, the shell side wall 26 is generally an arc-shaped surface, and the shell distal wall 25 is a circular arch; the shell 1 is provided with a first notch 16 and a second notch 27, the first notch 16 is arranged at the distal end of the shell 1, and the second notch 27 is arranged at the proximal end of the shell 1; the inner wall of the shell side wall 26 is provided with a gasket 20, the outer diameter of the gasket 20 is equivalent to the inner diameter of the corresponding position of the shell 1, and the center of the gasket 20 is a through hole 21, which is used to allow the shaft 10 to pass through the gasket 20 and limit the position of the shaft 10 in the shell 1. A plurality of bayonet holes 19 are arranged on the inner side of the edge of the side wall 26 of the shell, and a number of buckles 18 corresponding to the bayonet holes 19 are arranged on the inner side of the edge of the auxiliary plate 8. After the buckles 18 are combined with the bayonet holes 19, the auxiliary plate 8 and the side wall 26 of the shell are combined together to form a roughly cylindrical body; a flange 17 is arranged on the top of the auxiliary plate 8, and a protrusion 7 is arranged on the proximal end of the baffle wall 2. The space formed by the bottom of the protrusion 7, when the flange 17 is embedded in the space formed at the bottom of the protrusion 7, the auxiliary plate 8 and the baffle wall 2 form a whole in the vertical direction, and the flange 17 also forms an axial sliding track of the baffle wall 2 relative to the auxiliary plate 8, so that the baffle wall 2 can move forward or backward along the axial direction of the shell 1; the baffle wall 2 is constructed to also include forward and backward indicating arrows 14, and when external force drives the protrusion 7 according to the forward and backward indicating arrows 14, the baffle wall 2 moves forward or backward along the shell 1. The shaft 10 includes a proximal end and a distal end of the shaft. The proximal end of the shaft is fixedly provided with an operator 3, and then the proximal end of the shaft forms a rotatable shaft connection with the base 30. Specifically, the base 30 is configured to include an axial hole 22, and the proximal end of the shaft is inserted into the axial hole 22 to form a rotatable shaft connection with the base 30; the distal end of the shaft is detachably connected to the sampling brush 5, and the sampling brush 5 includes bristles 12, a shaft 11 for connecting the brush head, and a connector 6; the connector 6 is inserted into the distal end of the shaft 10, that is, connected with the shaft 10, and the connector 6 can be separated from the shaft 10 only after a certain external force is applied. The shape of the operator 3 is a cylinder, and the outer wall of the operator 3 is provided with anti-slip grooves. The position of the operator 3 corresponds to the position of the second notch 27 of the shell 1, and the position of the sampling brush 5 corresponds to the position of the first notch 16 of the shell 1. When an external force acts on the operator 3 to make it rotate circumferentially, the operator 3 drives the shaft 10 and the sampling brush 5 to rotate in the same direction, and the bristles 12 form friction with the cervical wall and obtain cells from the inner wall of the cervix. The proximal end of the baffle wall 2 is also provided with a clockwise or counterclockwise indicating arrow 15 for indicating the rotation direction of the operator 3. The proximal end of the baffle wall 2 also includes a window 9; the proximal end of the baffle wall 2 is also provided with a booster wing 4, which is a pair of boosters 4 and is arranged on both sides of the proximal end of the baffle wall 2. The booster wing 4 has two force-bearing surfaces, one force-bearing surface makes it easy to apply thrust, and the other force-bearing surface makes it easy to apply tension, so that the baffle wall can be switched between the first use state and the second use state. The proximal end of the sampler 100 also includes a handle 13, which is connected to the sampler through the base 30. The handle 13 is used to push the sampler forward or pull it backward as a whole, so that the sampler is pushed in or pulled out of the vagina.

In one embodiment, during the process of rotating the manipulator 3 to obtain cervical cells, the manipulator 3 is rotated at least 5 times.

Fig. 2 is a schematic diagram of the cervical sampler 100 in the first use state, which is the state of the sampler before and during the process of being pushed into the vagina, and the state of the sampler being pulled out of the vagina after completing the biological tissue collection; the sampler 100 includes a shell 1, and the upper part of the shell 1 is a baffle 2. The shell 1 and the baffle 2 form a roughly smooth cylindrical shape in the first use state, and the baffle 2 closes the first notch 16 of the shell 1, so that the sampling brush is closed inside the baffle 2, and the sampler is relatively smooth when entering the vagina. In order to make the sampler enter the vagina more smoothly, a lubricant can also be applied to the outside of the shell 1. After the sampler completes the sample collection, the sampler is switched to the first use state again and then taken out of the vagina to avoid the sample being contaminated during the extraction process and affecting the test results.

FIG3 is a schematic diagram of the cervical sampler 100 in the second use state, which is the state in which the sampler 100 is preparing or collecting biological tissue samples in the vagina. Under the action of the pulling force applied to the protrusion 7, the retaining wall 2 moves toward the proximal end along the shell 1, so that the sampler is in the state shown in FIG3; in this second use state, the sampling brush 5 is exposed from the first notch 16 on the shell, and at the same time, the operator 3 is also exposed from the window 9 on the retaining wall 2. At this time, the operator drives or rotates the operator 3 circumferentially through the window 9 by external force according to the direction indicated by the clockwise or counterclockwise arrow 15 for multiple times, for example, 5 times, and the operator 3 drives the sampling brush 5 to rotate in the same direction, and the bristles 12 contact and rub the inner wall of the cervix from the space formed by the first notch, thereby collecting sample tissue from the inner wall of the cervix. After completing the sample collection, the sampler switches back to the first use state shown in FIG2, and then the sampler is taken out from the vagina.

FIG4 is a schematic diagram of the local structure of the connection between the sampling brush and the shaft. As shown in the figure, the sampling brush 5 is connected to the shaft 10 through the shaft 11 and the connector 6 for connecting the brush head, that is, the connector 6 is inserted into the distal end of the shaft 10. When the sampling is completed, the operator clamps the shaft 11 with tweezers to apply external force, and pulls the connector 6 out of the distal end of the shaft 10 to remove the sampling brush, and then puts it into the sample collection container as a whole, and immerses it in the biological tissue preservation solution in the container, waiting for the next step of laboratory testing.

The cervical sampler of the present application adopts an ergonomic design, which is not only suitable for use by medical staff, but also suitable for self-operation by the sampled person. The cervical sampler of the present application is suitable for use in medical places, and is also suitable for self-use by the sampled person in non-medical places such as residences, making the sample collection process more flexible and protecting the privacy and user experience of the sampled person.

The preferred embodiments of the present invention are described above with reference to the accompanying drawings, but the scope of the present invention is not limited thereby. A person skilled in the art may implement the present invention in a variety of variations without departing from the scope and essence of the present invention, such as using a feature of one embodiment to obtain another embodiment. Any modification, equivalent substitution and improvement made within the technical concept of the present invention shall be within the scope of the present invention.

Claims (17)

1. A cervical sampler, comprising:

the shell comprises a shell side wall and a closed shell far end wall, wherein the shell side wall comprises a first notch which is arranged close to the shell far end wall;

A sampling brush configured to be received in the housing and to expose at least a portion of the sampling brush to a location of the first notch in at least one use condition;

A shaft including a shaft distal end and a shaft proximal end;

The shaft distal end is connected with the sampling brush, the shaft proximal end further comprises an operator, and the operator drives the shaft and the sampling brush to circumferentially rotate under the operation of external force, so that the sampling brush is contacted with a target sample near the first notch in a use state, and friction force is generated to obtain biological tissues.

2. The sampler according to claim 1, wherein: the device further comprises a retaining wall, wherein the retaining wall is sized and shaped to cover at least the first notch, and the retaining wall is arranged to switch between a first use state and a second use state under the action of external force;

In the first use state, the blocking wall covers the first notch;

in the second use state, the blocking wall is far away from the first notch, so that the sampling brush is exposed to the position where the first notch is located.

3. The sampler according to claim 2, wherein: the retaining wall is arranged to move axially along the housing side wall.

4. The sampler according to claim 2, wherein: the retaining wall is configured to slide circumferentially along the housing sidewall.

5. The sampler according to claim 2, wherein: the retaining wall is configured to further include a protrusion that, when operated by an external force, effects a switch between a first use state and a second use state.

6. The sampler according to claim 1, wherein: the manipulator is a rotary converter, anti-skidding lines are arranged on the outer wall of the rotary converter, and when the rotary converter circumferentially rotates under the action of external force, the manipulator drives the shaft so that the sampling brush can rotate in the same direction.

7. The sampler according to claim 2, wherein: the housing sidewall is configured to include a second notch, the position of the second notch corresponding to the position of the operator such that at least a portion of the operator is exposed to the position of the second notch; the retaining wall is configured to further include a window positioned to correspond to the operator when the retaining wall is in the second use state such that at least a portion of the operator is exposed.

8. The sampler according to claim 2, wherein: the proximal end of the retaining wall is further provided with a power assisting wing, and the power assisting wing is used for applying axial pushing force or pulling force to the retaining wall to enable the retaining wall to achieve switching between a first use state and a second use state.

9. The sampler according to claim 1, wherein: the proximal end of the housing is further provided with a base, and one side of the base is rotatably connected with the proximal end of the shaft.

10. The sampler according to claim 9, wherein: the other side of the base is configured to include a handle for applying axial pushing or pulling force to the sampler to enable the sampler to be placed in or withdrawn from the vagina.

11. The sampler according to claim 1, wherein: the housing distal wall is generally dome-shaped.

12. The sampler according to claim 1, wherein: the sampling brush is detachably connected with the shaft distal end.

13. The sampler according to claim 2, wherein: the auxiliary plate is fixedly connected with the shell; the auxiliary plate is in sliding connection with the retaining wall, so that the retaining wall can axially move relative to the shell.

14. The sampler according to claim 1, wherein: the biological tissue is cervical cells.

15. A cervical sampler kit, comprising:

a sampler as claimed in any one of claims 1 to 14;

A container sized to receive at least the sampling brush therein.

16. The kit of claim 15, wherein: the tissue preservation device also comprises auxiliary tools, wherein the auxiliary tools are any one or more of lubricants, forceps and biological tissue preservation solutions.

17. A self-operable cervical cancer cell sampler comprising:

A shaft including a shaft distal end and a shaft proximal end;

The sampling brush is used for acquiring a sample;

The outer wall of the manipulator is provided with anti-skid patterns, and when the manipulator rotates under the action of external force, the manipulator drives the shaft and the sampling brush to realize the same-direction rotation;

A housing comprising a housing side wall and a closed housing distal wall, the housing side wall comprising a first notch disposed proximate the housing distal wall; the housing sidewall is configured to include a second notch, the second notch being positioned to correspond to the position of the operator such that at least a portion of the operator is exposed to the position of the second notch;

The auxiliary plate is fixedly connected with the shell;

A blocking wall which is in sliding connection with the auxiliary plate and enables the blocking wall to axially move relative to the shell; the retaining wall is sized and shaped to cover at least the first gap, the retaining wall being configured to switch between a first use state and a second use state under the influence of an external force; the retaining wall is configured to further comprise a window, and the position of the window corresponds to the manipulator;

Wherein the sampling brush is configured to be received in the housing and to expose at least a portion of the sampling brush to the location of the first notch in at least one use condition;

In the first use state, the blocking wall covers the first notch;

In the second use state, the blocking wall is far away from the first notch, so that the sampling brush is exposed to the position where the first notch is located; and exposing at least a portion of the operator from the window;

Wherein the distal end of the shaft is connected with the sampling brush, and the proximal end of the shaft is connected with the manipulator;

The manipulator drives the shaft and the sampling brush to circumferentially rotate for 5 circles under the operation of external force, so that the sampling brush is contacted with a target sample near the first notch in a use state, and friction force is generated to acquire cervical cells.