CN110012844B - Underwater multifunctional integrated animal experiment equipment - Google Patents

Abstract

The invention is applicable to the technical fields of experimental equipment and scientific research instruments, and discloses an underwater multi-functional integrated animal experimental equipment, comprising a catheter, a stimulation device and a waterproof box, the waterproof box has a function for accommodating the stimulation device and a waterproof box. The inner cabin of the animal, the stimulation device is arranged in the waterproof box, the conduit includes a cable conduit and a supply conduit connected to the waterproof box, and a cable conduit connected to the stimulation device is pierced through the cable conduit. A cable, the supply conduit is communicated with the inner compartment. The underwater multifunctional integrated animal experiment equipment provided by the present invention can be used underwater, can carry out animal experiments under special environment and multimodal stimulation, is very convenient to install and use, and can be used for a long period of time. , the experimental effect is good.

Description

An underwater multifunctional integrated animal experiment equipment

technical field

The invention belongs to the technical field of experimental equipment and scientific research instruments, in particular to an underwater multifunctional integrated animal experimental equipment.

Background technique

Anxiety and depressive disorders are mental illnesses that seriously threaten people's health. The latest research data show that the incidence of anxiety disorders in the elderly is as high as 10%, the incidence in the general population is also 2% to 5%, and the incidence of depression in adolescents is about 2%. Its incidence increases with age. Most patients had co-morbid conditions of anxiety and depression. In the United States, these emotional disorders cost the economy more than $150 billion annually and can lead to serious social problems such as suicide. Working in special environments for a long time often causes a great burden on people's psychology. For example, long-term underwater operations will significantly increase the probability of anxiety and depression. Therefore, understanding the influence of the environment (especially the underwater environment) on anxiety and depression, exploring the mechanism of anxiety and depression disorders, and seeking effective drug treatment methods have become urgent issues to be solved. As a necessary complement to human studies, the use of animal models will help to systematically study the effects of specific environments on emotions at the neural level. For this we need a multifunctional integrated animal experiment box that can be used in special environments.

The current animal experiment box mainly affects mice by changing a certain environmental factor under the conditions of controlled ventilation and diet. For example, in the patent document with the patent application number of CN201720589442, an animal experiment box is introduced, which can carry out various experiments using limited experimental space, and provides experimental rodents with the same temperature, humidity and ventilation equipment. , Through the LED lights above the experimental box, different lighting modes can be adjusted at will.

For example, the patent with the application number of CN201410123744 is a more complicated experimental animal box driven by a single chip system. It is composed of a single-chip system controller, a driving circuit module, a digital tube display module, an animal pressing rod module, an infrared reflection probe detection module, an animal behavior box, a social device, a feeding device, and a serial port setting module of the computer. It can systematically and quantitatively detect the motivation of animals for socialization or feeding.

The above-mentioned animal experiment box is not designed for use in special environments such as underwater, so its tightness cannot be guaranteed. When working underwater, it may cause short circuits in the experiment box and drowning of experimental animals. This greatly limits the application scope of the animal experiment box, and it is impossible to couple the sensory stimulation designed for small animals with the underwater environment. In addition, the above-mentioned experimental animal boxes are all designed for short-term animal experiments, which cannot provide supplementary supplies for experimental animals, and are not suitable for long-term animal experiments.

In addition, the existing animal experiment boxes basically can only give experimental animals a single and simple stimulus, and the LED lighting mode or digital tube display is not complicated enough.

SUMMARY OF THE INVENTION

The present invention aims to solve at least one of the above technical problems, and provides an underwater multifunctional integrated animal experiment equipment, which can conduct animal experiments for a long time under special environment and multimodal stimulation, and the experiment effect is good.

The technical scheme of the present invention is: an underwater multifunctional integrated animal experiment equipment, comprising a catheter, a stimulation device and a waterproof box, the waterproof box has an inner compartment for accommodating the stimulation device and the animal, the The stimulation device is arranged in the waterproof box, the conduit includes a cable conduit connected to the waterproof box and a supply conduit, and a cable connected to the stimulation device is pierced through the cable conduit, and the supply conduit communicated with the inner compartment.

Optionally, the waterproof box body includes an upper box body and a lower box body, the upper box body and the lower box body are combined and fixedly connected by a locking member, and the upper box body and the lower box body are combined to form the interior; or,

The waterproof box body includes a box body with an opening on one side, an openable sealing door is provided at the opening of the box body, and the box body and the sealing door form the inner compartment.

Optionally, a partition is arranged between the upper box and the lower box, and the partition divides the inner cabin into an upper cabin and a lower cabin, wherein the stimulation device is arranged in the upper cabin, and the supply conduit is located in the upper cabin. The food supply pipe, water supply pipe and ventilation pipe are communicated with the lower compartment through the holes in the bulkhead;

Alternatively, a baffle is arranged in the box, and the baffle partitions the inner cabin into an upper cabin and a lower cabin, wherein the stimulation device is arranged in the upper cabin, and the food supply pipes, water supply pipes and ventilation pipes in the supply conduits A conduit communicates with the lower compartment through holes in the bulkhead.

Optionally, a sealing ring is provided between the upper case body and the lower case body; or, a sealing ring is provided between the sealing door and the case body.

Optionally, the supply conduit is provided with a food supply conduit, a water supply conduit and a ventilation conduit.

Optionally, the lower compartment is provided with water bottles or/and feeders.

Optionally, a power cable and a control cable are arranged in the cable conduit.

Optionally, the stimulation device includes at least one of a visual stimulation device, an auditory stimulation device and a tactile stimulation device.

Optionally, the stimulation device includes a display, and the stimulation device further includes an ultrasonic generator or a multi-band sound wave generator.

Optionally, the bottom of the box body is provided with feet or/and counterweights.

The invention provides an underwater multifunctional integrated animal experimental equipment that can be used underwater. Cables such as power lines and signal lines can enter the waterproof box from a plastic pipe (cable conduit), and the drinking water supply pipe, The food supply pipe and ventilation pipe enter the waterproof box from another plastic pipe (supply conduit), which not only ensures the waterproof sealing of the device, but also ensures the supply of air, drinking water and food. The waterproof box is equipped with a display and an ultrasonic generator, which can give the experimental animals corresponding visual and auditory stimulation. The installation and use of the underwater multi-functional integrated animal experiment equipment is also very convenient, the use time is sufficient for long-term animal experiments, and animal experiments can be carried out in special environments and multimodal stimulation, and the experiment effect is good.

Description of drawings

In order to illustrate the technical solutions in the embodiments of the present invention more clearly, the following briefly introduces the drawings required in the embodiments. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can also be obtained from these drawings without any creative effort.

Fig. 1 is a three-dimensional schematic diagram of a kind of underwater multifunctional integrated animal experimental equipment provided by the embodiment of the present invention;

FIG. 2 is a schematic plan view of an underwater multifunctional integrated animal experiment equipment provided by an embodiment of the present invention.

Detailed ways

In order to make the objectives, technical solutions and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention, but not to limit the present invention.

It should be noted that the terms "arrangement" and "connection" should be understood in a broad sense, for example, it may be directly arranged and connected, or indirectly arranged and connected through a central component or a central structure.

In addition, if there are "vertical", "horizontal", "length", "width", "thickness", "top", "bottom", "front", "rear", "left", " "Right", "vertical", "horizontal", "top", "bottom", "inside", "outside" etc. indicate the terms of orientation or positional relationship, which are based on the orientation or positional relationship shown in the drawings or conventional The placement state or the use state is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the structure, feature, device or element referred to must have a specific orientation or positional relationship, nor must it be constructed in a specific orientation and operation, and therefore should not be construed as limiting the present invention. In the description of the present invention, unless otherwise specified, "plurality" means two or more.

Each specific technical feature and each embodiment described in the detailed description can be combined in any suitable manner under the circumstance that is not contradictory, for example, different specific technical features/embodiments can be combined to form different implementations In order to avoid unnecessary repetition, various possible combinations of specific technical features/embodiments in the present invention will not be described separately.

As shown in FIG. 1 and FIG. 2 , an underwater multifunctional integrated animal experiment equipment provided by an embodiment of the present invention includes a waterproof box 10 , a catheter and a stimulation device. The waterproof case 10 has an inner compartment for accommodating the stimulation device and experimental animals. The experimental animals can be small animals, such as mice, rabbits, etc., or cats, dogs, primates (monkeys) and the like. The stimulation device is arranged in the waterproof box 10, and the conduit includes a cable conduit 20 and a supply conduit 30 connected to the waterproof box 10. The cable conduit 20 is provided with cables (power cables, control wires) connected to the stimulation device. cable). In the supply conduit 30, a food supply conduit, a water supply conduit and a ventilation conduit communicate with the inner compartment. The waterproof case 10 can be placed underwater and the inner compartment will not accidentally enter the water. The food supply pipe, water supply pipe and ventilation pipe in the supply pipe 30 can provide the necessary conditions for the survival of the animal, such as air supply (ventilation), water supply (water supply), food supply and the like. The stimulation device can stimulate the experimental animal, such as one or more of ultrasonic stimulation, visual stimulation, and tactile stimulation. A power cable and a control cable (signal cable) can be passed through the cable conduit 20, and one end of the power cable and the control cable (signal cable) is connected to the stimulation device in the inner cabin. The other end of the cable (signal cable) (that is, the end protruding from the water surface) can be connected to the control device (computer, ultrasonic generator), etc.; the drinking water supply pipe (water supply conduit) in the supply conduit is used to supplement drinking water for small animals, Food supply tubes are used to deliver food. The ventilation duct ensures that the air pressure, air concentration and temperature of the space where the small animals are kept within a reasonable range; adjusting the position and air flow rate of the ventilation duct can give experimental animals specific tactile stimulation. The waterproof box 10 provides and defines the activity space of the animal and ensures the airtightness at a certain underwater depth. In this way, it not only ensures the waterproof and sealing performance of the device, but also ensures the supply of air, drinking water and food. Survival conditions, the experiment can be carried out for several days or tens of days or even longer, and the use time is enough to meet long-term animal experiments. The waterproof box 10 is equipped with a stimulation device, which can provide corresponding visual and auditory stimulation to the experimental animals as required, and the equipment is easy to install and use, and animal experiments can be carried out in special environments and multimodal stimulation, and the experimental effect is good.

Specifically, as a first possible embodiment of the waterproof box 10 , the waterproof box 10 can include an upper box 11 and a lower box 12 , and the upper box 11 and the lower box 12 are combined and fixedly connected by the locking member 13 . The upper box 11 and the lower box 12 are combined to form an inner compartment; the upper box 11 can be mainly placed with electronic devices such as stimulation devices, and the lower box 12 can be mainly placed with water bottles, feeders and other animal feeding and supply devices. A partition 14 may be arranged between the upper box 11 and the lower box 12, the upper box 11 and the lower box 12 can be fixedly connected to the partition 14, and the partition 14 separates the inner cabin into the upper cabin 101 and the lower cabin 102 , wherein the stimulation device is arranged in the upper cabin 101 , and the food supply pipe, water supply conduit and ventilation conduit in the supply conduit 30 enter from the upper cabin 101 and communicate with the lower cabin 102 through the holes on the partition 14 . The installation and maintenance of the equipment are convenient. The upper box body 11 and the lower box body 12 can be disassembled to perform maintenance work such as inspection and cleaning of the relevant stimulation device and feeding device respectively. A sealing ring may be provided between the upper case body 11 and the lower case body 12 to further ensure the reliability of sealing.

As a second possible embodiment of the waterproof box 10, the waterproof box 10 includes a box with an opening on one side, and an openable sealing door is provided at the opening of the box. The sealing door can be opened by turning or pushing and pulling, and the sealing door is closed After it is in place, there will be no water leakage between the sealing door and the box body, and the safety and reliability are good. The box body and the sealing door form an inner compartment, and a partition 14 is arranged in the box. The partition 14 separates the inner compartment into an upper compartment 101 and a lower compartment 102, wherein the stimulation device is arranged in the upper compartment 101, and the food supply pipe in the supply conduit 30 is provided. , the water supply conduit and the ventilation conduit are communicated with the lower compartment 102 through the holes on the partition plate 14 . That is, maintenance work such as inspection and cleaning of related stimulation devices and feeding devices is carried out by means of the side door. A sealing ring or a sealing strip can be arranged between the sealing door and the box to further ensure the reliability of sealing.

As a third possible embodiment of the waterproof box 10, the waterproof box 10 includes a box, the inner compartment of the box is divided into an upper compartment 101 and a lower compartment 102, and the box is respectively provided with an upper compartment door and a lower compartment door, wherein The upper cabin door is correspondingly arranged on the side or top of the upper cabin 101 , and the lower cabin door is correspondingly arranged at the side or bottom of the lower cabin 102 . A sealing ring or a sealing strip can be arranged between the upper cabin door and the lower cabin door and the box to further ensure the reliability of sealing.

As a fourth possible embodiment of the waterproof box 10, the waterproof box 10 includes a box body and a sealing door arranged on the side of the box or a sealing cover on the top. Different from the above-mentioned way of having the upper cabin 101 and the lower cabin 102, this In the embodiment, only one compartment may be provided, and the stimulation device and the feeding device are all provided in this compartment. Of course, the waterproof case 10 can also adopt other structural forms, which also belong to the protection scope of the present invention.

In this embodiment, the supply conduit 30 is provided with a water supply conduit, a ventilation conduit and a food supply conduit. One end of the supply conduit 30 can be sealed and connected to the waterproof case 10 through a structure such as a threaded pipe joint, and the other end of the supply conduit 30 can be extended to the water surface and fixed. The water supply conduit may be connected to a water supply tank or a water pump or the like. The ventilation duct can be connected with a blower or a compressed air tank. The food supply tube can be connected to a food storage container (for automatic supply) or a funnel (for manual supply), etc.

Specifically, the inner compartment (lower compartment 102 ) may be provided with a water bottle 50 or/and a feeder, and the water bottle 50 may be a nipple-type water dispenser. The water supply bottle 50 can be an automatic water supply device, and the automatic water supply device can include a water storage bottle and a water supply food bowl. A certain amount of water is stored in the water supply and food bowl. , it can automatically maintain the water level line of the water feeding basin, and the experimental animals can drink water at any time. The water supply conduit may be communicated with the water supply bottle 50 (water storage bottle). Alternatively, the water supply bottle 50 is a common open container, and the water supply conduit extends into the open container and replenishes water regularly or under manual control. A liquid level sensor can also be arranged in the open container, and when the liquid level is lower than the set value, the water supply conduit can automatically replenish water into the open container. The feeder can be an ordinary feeding container or an automatic feeder that can be opened and closed electrically.

In a specific application, the cable in the cable guide 20 is connected with a control device for controlling the stimulation device. The control device can be a computer, a single-chip microcomputer, etc. Of course, the control device can also be built in the inner cabin, and transmit information and data through wireless transmission, that is, the control device can be provided with a wireless communication module (such as 4G module, 5G module, WIFI module, Bluetooth module, etc.). In this way, only the power cable needs to be arranged in the cable guide 20 .

Specifically, the stimulation device may include at least one of a visual stimulation device, an auditory stimulation device, and a tactile stimulation device. Therefore, common visual stimuli in the field of neuroscience, such as fringe patterns and enlarged disc patterns, can be applied to the stimulation device, and multimodal stimulation coupling such as visual and auditory can also be realized.

In this embodiment, the stimulation device includes a display 42, and the stimulation device further includes an ultrasonic generator 41 or a multi-band sound wave generator. A speaker may be provided on the display 42, and the speaker may also be provided independently. The tactile stimulation device can be a ventilation/air supply pipeline. By adjusting the airflow size, the outlet position of the ventilation/air supply pipeline, the smell of the airflow, etc., tactile stimulation can be applied to the experimental animals.

Specifically, the bottom of the box is provided with feet 15 or/and counterweights, so that the box can sink into the water stably. In specific applications, a rechargeable backup battery can also be set at the bottom of the box, and the backup battery can play a role of counterweight for emergency use.

In a specific application, a temperature adjustment device may also be provided in the upper cabin 101 , and the temperature adjustment device may be a semiconductor refrigeration device or the like, so as to adjust the temperature of the lower cabin 102 .

In specific applications, a partition can also be provided in the wall of the waterproof box 10, and the partition can be evacuated or filled with thermal insulation materials, so that the underwater multifunctional integrated animal experiment equipment can be used in severe cold and hot environments.

In a specific application, a hook or a lifting ring can also be provided on the top or side of the waterproof box 10, and the diving depth of the box can be adjusted by a hanging rope connected to the hook or the lifting ring. Of course, a suspension rod can also be fixedly connected to the top of the waterproof box 10, which has high stability.

In specific applications, one or more groups of cameras with different angles can also be arranged in the inner compartment of the waterproof box 10 to capture and record the video in the inner compartment in real time, so as to better study the behavior of experimental animals under different stimuli. reaction. The camera can have a built-in wireless transmission module, or can be transmitted to the control device through a data cable running through the cable conduit 20. The control device can include an input and output device (such as a touch screen or a keyboard and a display 42), a storage and recording module (such as computer host and built-in hard disk), etc.

In a specific application, an oxygen content sensor can also be provided in the inner compartment of the waterproof box 10, and the oxygen content sensor can be connected to the control device by wire (through the cable of the cable conduit 20) or wirelessly. When the oxygen content exceeds When the range is set, the control device will send an alarm message to the scientific research personnel, and it can also automatically start the ventilation pump to adjust the oxygen content of the inner cabin through the air supply pipeline.

In specific applications, a water immersion sensor can also be provided in the inner compartment of the waterproof box 10. When there is water accumulation in the inner compartment, the water immersion sensor can send a signal in time, and the control device will send an alarm message to the scientific research personnel, so that the scientific research personnel can timely reaction treatment.

In specific applications, temperature and humidity sensors may also be provided in the inner compartment of the waterproof box 10 .

In a specific application, a bio-sensing device that can be worn on the body of the experimental animal can also be provided in the inner compartment of the waterproof box 10 , and the bio-sensing device can be wired (through the cable of the cable conduit 20 ) or wireless. connected to the control device. The biosensing device may have at least one of a thermometer, a heart rate monitor, a blood pressure monitor, and a blood glucose sensor.

In specific applications, lighting devices, such as LED lights, etc., may also be provided in the inner compartment of the waterproof box 10 .

In specific applications, a sink can also be provided at the bottom of the inner cabin. A sewage pipe extending out of the waterproof box 10 can be connected to the sink, and a sewage pump can be connected to the sewage pipe. Of course, it is also not necessary to provide a sink, a sewage pipe, etc., and the inner cabin can also be kept dry and clean by means of a mat or the like.

In a specific application, an exhaust pipe can also be arranged on the top or side of the inner cabin, and the exhaust pipe can pass through the supply duct 30 . Of course, the ventilation pipe and the exhaust pipe can also share a pipeline.

In a specific application, a pressure-type water depth sensor may also be provided on the outer side of the waterproof box 10 .

In specific applications, the dimensions of the waterproof box 10 and the display 42 can be set according to actual conditions to suit animals of different sizes.

In this embodiment, as shown in FIG. 1 , the waterproof box 10 is divided into upper and lower compartments separated by a partition 14 , and a counterweight module is installed in the lower part of the box. There is a rubber sealing ring 16 between the two layers, which can be sealed and waterproof by tightening the upper and lower layers with screws. The display 42 and the ultrasonic generator 41 are arranged on the upper compartment (upper cabin 101 ) of the box. The display 42, the power line, the signal line and other related cables of the ultrasonic generator 41 lead to the water surface through a plastic tube (the cable conduit 20). The drinking water supply pipe, food supply pipe and ventilation pipe enter the upper compartment of the animal experiment box through another plastic pipe (supply conduit), and communicate with the lower compartment (lower compartment 102) through the through hole of the partition plate 14, wherein The drinking water supply pipe is connected to the water supply bottle 50 of the lower compartment.

At the beginning of the experiment, disassemble the test box (waterproof box 10) that has not been fixed with the partition 14, put the experimental animals (take mice as an example) in the lower compartment, and then use screws to pass through the upper and lower parts of the test box and pass through the upper and lower parts of the test box. The partition 14 is fixed. During the experiment, put the whole test box into the water tank and fill the water tank with water until the test box is at a certain depth below the liquid surface. The power line of the display 42 is connected to an external power supply, and the signal line is connected to an external computer, and the display 42 is driven by a program of the computer to display a pattern. The signal line (USB connector) connected to the ultrasonic generator 41 is connected to an external interface, and drives it to work to generate ultrasonic waves of a set frequency. The above allows the mice to receive visual and ultrasonic stimulation. During the whole experiment, the ventilation pipe is connected to the outside atmosphere to ensure good ventilation in the test box, and its position and air flow rate can be adjusted according to the needs of the experiment, and specific tactile stimulation can be given to the experimental animals; the drinking water supply pipe regularly supplies 50 Mice were supplemented with drinking water; food supply tubes were used for food delivery. In the experimental box, the entire experiment can last anywhere from a few days to a few weeks.

The display 42 can be a conventional display 42 on the market, which can be fixed on the upper compartment, and the size can be customized according to the needs. The ultrasonic generator 41 can be fixed on the upper compartment by tape or screws. In this embodiment, the display 42 and the ultrasonic generator 41 included in the stimulation module can respectively stimulate the experimental animals visually and soundly. The computer adjusts the input signal through the signal line and the USB interface line connected to the first two, and the control software is applicable It is suitable for systems that support driving such hardware such as window system, android, linux or ios.

The embodiment of the present invention provides an underwater multifunctional integrated animal experiment equipment that can be used underwater. Cables such as power lines and signal lines can enter the waterproof box 10 from a plastic tube (cable conduit 20 ). The drinking water supply pipe, the food supply pipe and the ventilation pipe enter the waterproof box 10 from another plastic pipe (the supply conduit 30 ), which not only ensures the waterproof sealing of the device, but also ensures the supply of air, drinking water and food. The waterproof box 10 is equipped with a display 42 and an ultrasonic generator 41, which can give corresponding visual and auditory stimuli to experimental animals, and can also give experimental animals specific tactile stimuli by adjusting the position of the ventilation pipe and the air flow rate. The installation and use of the underwater multi-functional integrated animal experiment equipment is also very convenient, and there is no strong limitation on the use time, which is sufficient for long-term animal experiments. .

The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modification, equivalent replacement or improvement made within the spirit and principle of the present invention shall be included in the protection scope of the present invention. Inside.

Claims (7)

1. an underwater multifunctional integrated animal experiment equipment, is characterized in that, comprises conduit, stimulation device and waterproof casing, described waterproof casing has the inner cabin for accommodating described stimulation device and animal, described stimulation The device is arranged in the waterproof box, the conduit includes a cable conduit connected to the waterproof box and a supply conduit, the cable conduit is provided with a cable connected to the stimulation device, and the supply conduit communicates in said inner compartment; The waterproof box body includes an upper box body and a lower box body, the upper box body and the lower box body are combined and fixedly connected by a locking member, and the upper box body and the lower box body are combined to form the inner cabin; or , The waterproof box body includes a box body with an opening on one side, an openable sealing door is provided at the opening of the box body, and the box body and the sealing door form the inner compartment; A partition is arranged between the upper box and the lower box, and the partition divides the inner cabin into an upper cabin and a lower cabin, wherein the stimulation device is arranged in the upper cabin, and the food supply pipe in the supply conduit , the water supply conduit and the ventilation conduit are communicated with the lower cabin through the holes on the bulkhead; Alternatively, a baffle is arranged in the box, and the baffle partitions the inner cabin into an upper cabin and a lower cabin, wherein the stimulation device is arranged in the upper cabin, and the food supply pipes, water supply pipes and ventilation pipes in the supply conduits A conduit communicates with the lower compartment through a hole in the bulkhead; The supply conduit is provided with a food supply conduit, a water supply conduit and a ventilation conduit. 2. A kind of underwater multifunctional integrated animal experimental equipment as claimed in claim 1, is characterized in that, between described upper case body and described lower case body is provided with a sealing ring; A sealing ring is arranged between the boxes. 3. The underwater multifunctional integrated animal experiment equipment according to claim 1, wherein the lower cabin is provided with a water supply bottle or/and a feeder. 4 . The underwater multifunctional integrated animal experiment equipment according to claim 1 , wherein a power cable and a control cable are arranged in the cable conduit. 5 . 5. a kind of underwater multifunctional integrated animal experimental equipment as described in any one of claim 1 to 4, is characterized in that, described stimulation device comprises at least one in visual stimulation device, auditory stimulation device and tactile stimulation device kind. 6. a kind of underwater multifunctional integrated animal experimental equipment as described in any one of claim 1 to 4, is characterized in that, described stimulation device comprises display, and, described stimulation device also comprises ultrasonic generator or multiple Band Sonic Generator. 7. The underwater multifunctional integrated animal experiment equipment according to any one of claims 1 to 4, wherein the bottom of the box body is provided with feet or/and counterweights.

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