CN109894175B

CN109894175B - Fluid control module

Info

Publication number: CN109894175B
Application number: CN201910290725.1A
Authority: CN
Inventors: 郝书顺
Original assignee: Shijiazhuang Hipro Biotechnology Co Ltd
Current assignee: Shijiazhuang Hipro Biotechnology Co Ltd
Priority date: 2019-04-11
Filing date: 2019-04-11
Publication date: 2024-05-17
Anticipated expiration: 2039-04-11
Also published as: CN109894175A

Abstract

The invention relates to a fluid control module, which comprises a first chamber and a second chamber communicated with the first chamber through a siphon pipeline, wherein two ends of the siphon pipeline are respectively connected with the first chamber and the second chamber, a ventilation pipeline for communicating the first chamber with the atmosphere is arranged on the first chamber, and a temperature regulating device for regulating the temperature of the second chamber is correspondingly arranged at the position of the second chamber; the invention realizes the communication of the first chamber and the second chamber under specific conditions, and is similar to a valve structure, and the valve is opened under specific conditions, so that the liquid in the two chambers is mixed.

Description

Fluid control module

Technical Field

The present invention relates to a fluid control module.

Background

In life science, medical field or other fields, a series of experimental operations are often required to be performed on a sample, a proper reagent is required to be added at a proper time in the process, the series of operations are often very complex, and a reagent tray device capable of realizing liquid transfer in the rotation process for performing the test has been designed, and in the reagent tray, realizing the transfer of the liquid under a specific condition is an important function.

Disclosure of Invention

The invention aims to provide a fluid control module capable of realizing liquid transfer under specific conditions.

The technical scheme adopted by the invention is as follows: the utility model provides a fluid control module, its includes first room and the second room that is linked together with first room through the siphon pipeline, the both ends of siphon pipeline are connected with first room and second room respectively be provided with the vent pipe who is used for communicating first room with the atmosphere on the first room, be provided with the attemperator who is used for adjusting second room temperature in the position correspondence of second room.

Further, the temperature adjusting device adopts a semiconductor refrigerating sheet.

Further, a first fluid outlet is arranged on the first chamber, a fluid inlet is arranged on the second chamber, and two ends of the siphon pipeline are respectively communicated with the first fluid outlet and the fluid inlet.

Further, the first chamber, the second chamber and the siphon tube are all arranged on a rotatable reagent disk.

Further, the first chamber is positioned radially inward relative to the position of the second chamber.

Further, a second fluid outlet is provided in the bottom of the second chamber, which communicates with the first flow channel for transporting the liquid in the second chamber to a next position.

Further, a reagent pack is provided in the second chamber.

Further, the top end of the siphon pipeline is higher than the liquid level in the first chamber and the second chamber.

The invention has the positive effects that: the invention realizes the communication of the first chamber and the second chamber under specific conditions, and is similar to a valve structure, and the valve is opened under specific conditions, so that the liquid in the two chambers is mixed. When liquid is added into the two chambers respectively, a section of gas is sealed in the siphon pipeline to separate the liquid in the first chamber from the liquid in the second chamber, the non-liquid part in the second chamber is a compressible medium, the second chamber is heated by the temperature regulating device, the compressible medium in the second chamber expands, the liquid in the second chamber is pressed into the siphon pipeline until the gas in the siphon pipeline is discharged through the ventilation pipeline of the first chamber, the communication between the first chamber and the second chamber is realized, and then the liquid in the first chamber can be conveyed into the second chamber by reducing the temperature or increasing the rotating speed of the invention.

Drawings

FIG. 1 is a schematic diagram of the structure of the present invention.

Detailed Description

As shown in fig. 1, the invention comprises a first chamber 1 and a second chamber 4 communicated with the first chamber 1 through a siphon pipeline 3, wherein two ends of the siphon pipeline 3 are respectively communicated with the first chamber 1 and the second chamber 4, a ventilation pipeline 6 for communicating the first chamber 1 with the atmosphere is arranged on the first chamber 1, and a temperature regulating device for regulating the temperature of the second chamber 4 is correspondingly arranged at the position of the second chamber 4. A first fluid outlet 2 is arranged in the first chamber 1, a fluid inlet 5 is arranged in the second chamber 4, two ends of the siphon pipeline 3 are respectively communicated with the first fluid outlet 2 and the fluid inlet 5, and the first fluid outlet 2 and the fluid inlet 5 are respectively positioned below the liquid level in the first chamber 1 and the second chamber 4. The temperature regulating device may be applied to the second chamber 4 only or to the whole device to heat the whole device, with the same effect.

When in actual use, reagents can be prefabricated in the second chamber 4, reagent packages can be placed in the second chamber 4, the reagent packages can be opened under the action of centrifugal force, liquid in the reagent packages enters the second chamber 4, the reagent packages can be structurally fixed in the second chamber 4 by adopting a package-shaped structure with ends bonded together through hot pressing, the hot pressing degree is controlled, and the reagent packages can be opened under certain centrifugal force or can also be opened by adopting a needling structure. The temperature regulating device adopts a semiconductor refrigerating sheet, and can perform heating or cooling operation on the second chamber 4.

In use, liquid is introduced into the first chamber 1 and the second chamber 4, and in order to prevent the liquid in the first chamber 1 from breaking through the restriction of the siphon pipe 3 and conducting the two chambers in advance, the topmost position of the siphon pipe 3 should be higher than the liquid level in the first chamber 1 and the second chamber 4. At this point, there is a length of gas in the siphon 3 separating the liquid in the first and second chambers 1 and 4, and at this point there is a sealed compressible medium above the liquid level in the second chamber 4. When the temperature of the second chamber 4 is raised by means of the temperature regulating device, the compressible medium in the second chamber 4 expands, whereby the liquid in the second chamber 4 is transported through the siphon towards the first chamber 1 until the gas located in the siphon 3 is discharged through the first chamber 1, whereby fluid communication between the first chamber 1 and the second chamber 4 is achieved. The second chamber 4 is then subjected to a cooling operation, the compressible medium in the second chamber 4 contracting, drawing the liquid in the first chamber 1 into the second chamber 4, and then transporting the liquid to the next step by means of the first flow channel 9. At the bottom of the second chamber 4 a second fluid outlet 8 is provided, a first fluid channel 9 being in communication with said second fluid outlet 8.

For the first flow channel 9, its outlet should be higher than the height of the first chamber 1, the siphon 3 and the second chamber 4, so as to prevent liquid from being discharged from the first flow channel 9 during the above-mentioned process.

In addition to the above-described cooling operation, the first chamber 1, the second chamber 4, and the siphon 3 may be disposed on the rotatable reagent disk 7, and the first chamber 1 may be located radially inward with respect to the second chamber 4 (i.e., the distance between the first chamber 1 and the rotational axis of the reagent disk is smaller than the distance between the second chamber 4 and the rotational axis of the reagent disk). The minimum distance between the siphon 3 and the centre of rotation should be smaller than the minimum distance between the liquid level in the first and second chambers 1, 4 and the centre of rotation. The rotational speed of the reagent disk 7 is increased, and the liquid in the first chamber 1 is similarly caused to generate centrifugal force, and the liquid is transported from the first chamber 1 to the second chamber 4 by the centrifugal force.

The siphon tube 3 of the present invention does not necessarily have to communicate with the bottom ends of the first and second chambers 1 and 4. When communicating with the bottom ends of the first chamber 1 and the second chamber 4, the liquid in the first chamber 1 and the second chamber 4 can be entirely discharged. When the siphon 3 communicates with the middle of the first and second chambers 1, 4, it is also ensured that the first fluid outlet 2 and the fluid inlet 5 are below the liquid level of the respective chambers, at which time only liquid located above the first fluid outlet 2 and the fluid inlet 5 is transported to the other chambers, below which liquid will not be transported. While this design does not allow all of the liquid in the chamber to be transported away, there are specific applications where this is desirable, for example when there are solid particles with a bottom in the first chamber 1, and this is achieved by this design only when the supernatant is to be transported away.

The present application provides a fluid control module similar in function to a valve, in which liquid in the first chamber 1 and the second chamber 4 is not conducted in a normal state, and in which liquid in the first chamber 1 and the second chamber 4 is conducted under specific conditions, so as to meet the requirement that liquid needs to be added at a specific time when the reagent disk is used. Finally, both radially inward and radially outward are relative to the center of rotation of the reagent disk 7 in the present application.

The above embodiments are only for illustrating the technical solution of the present invention, and are not limiting; although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A fluid control module is characterized by comprising a first chamber (1) and a second chamber (4) communicated with the first chamber (1) through a siphon pipeline (3), wherein a ventilation pipeline (6) for communicating the first chamber (1) with the atmosphere is arranged on the first chamber (1), and a temperature regulating device for regulating the temperature of the second chamber (4) is correspondingly arranged at the position of the second chamber (4);

The first chamber (1), the second chamber (4) and the siphon pipeline (3) are arranged on a rotatable reagent disk (7);

a reagent pack is arranged in the second chamber (4), and the reagent pack is opened under the action of centrifugal force;

The top end of the siphon pipeline (3) is higher than the liquid level in the first chamber (1) and the second chamber (4);

after the reagent pack is opened under the action of centrifugal force, liquid in the reagent pack enters the second chamber (4);

When in use, liquid is introduced into the first chamber (1) and the second chamber (4), a section of gas is arranged in the siphon pipeline (3) to separate the liquid in the first chamber (1) and the liquid in the second chamber (4), and a sealed compressible medium exists above the liquid level in the second chamber (4); the temperature of the second chamber (4) is increased by utilizing the temperature regulating device, a compressible medium in the second chamber (4) expands, liquid in the second chamber (4) is conveyed to the first chamber (1) through a siphon pipeline until gas in the siphon pipeline (3) is discharged through the first chamber (1), and the first chamber (1) is communicated with the fluid in the second chamber (4); then the second chamber (4) is cooled, the compressible medium in the second chamber (4) contracts, and the liquid in the first chamber (1) is sucked into the second chamber (4).

2. A fluid control module according to claim 1, wherein the temperature regulating device employs semiconductor cooling fins.

3. A fluid control module according to claim 1, characterized in that a first fluid outlet (2) is provided in the first chamber (1) and a fluid inlet (5) is provided in the second chamber (4), both ends of the siphon conduit (3) being in communication with the first fluid outlet (2) and the fluid inlet (5), respectively.

4. A fluid control module according to claim 3, characterized in that the position of the first chamber (1) is radially inward relative to the position of the second chamber (4).

5. A fluid control module according to claim 1, characterized in that a second fluid outlet (8) is provided in the bottom of the second chamber (4), which second fluid outlet (8) communicates with the first flow channel (9) for transporting the liquid in the second chamber (4) to the next location.