CN210090491U - Liquid quantitative transfer device based on centrifugal force - Google Patents

Abstract

The utility model relates to a liquid ration transfer device based on centrifugal force, it includes the measuring chamber, with the measuring chamber through the overflow room of first fluid channel intercommunication, set up the fluid outlet at the outside end of measuring chamber, the control flap that is linked together with the fluid outlet and be used for making measuring chamber or overflow room and atmosphere intercommunication's second channel, when control flap is triggered, the liquid in the measuring chamber is discharged through the fluid outlet, be provided with inlet channel and overflow outlet at the top of measuring chamber, there is the overflow inlet on the overflow room, the both ends of first fluid channel are linked together with overflow outlet and overflow inlet respectively; the utility model discloses under the effect of centrifugal force, can fill the measuring chamber with the liquid that gets into from inlet channel, unnecessary liquid enters into the overflow room, then control flap opens, will measure the whole discharges of indoor liquid, and the indoor liquid of overflow can not discharge, alright realize the function that whole measuring chamber volumetric liquid ration then shifted.

Description

A liquid quantitative transfer device based on centrifugal force

technical field

The utility model relates to a liquid quantitative transfer device based on centrifugal force.

Background technique

In the fields of medical testing and biochemical testing, it is often necessary to perform a series of testing processes on fluid samples. In modern medicine, a reagent that can perform multiple tests on samples at one time has been designed on a disc structure. disk, such as the Chinese patent with the application number of 201810450478.2. Among these applications, one of the most important operations is the precise measurement of liquids and the transfer of quantitative liquids to specific areas for biochemical reactions. Therefore, it is very important to design a structure that can realize quantitative transfer of liquid.

Utility model content

The technical problem to be solved by the present invention is to provide a liquid quantitative transfer device based on centrifugal force, which can realize the quantitative liquid transfer of liquid under specific conditions.

The technical scheme adopted by the utility model is: a liquid quantitative transfer device based on centrifugal force, which comprises a measurement chamber, an overflow chamber communicated with the measurement chamber through a first fluid channel, a fluid outlet arranged at the outer end of the measurement chamber, and The second fluid channel communicated with the fluid outlet and the second channel used to communicate the measurement chamber or the overflow chamber with the atmosphere, a control valve is arranged on the second fluid channel, when the control valve is triggered, the liquid in the measurement chamber will pass through. The fluid outlet is discharged, an inlet channel and an overflow outlet are arranged on the top of the measuring chamber, an overflow inlet is arranged on the overflow chamber, and both ends of the first fluid channel are respectively communicated with the overflow outlet and the overflow inlet.

Further, the second channel is arranged on the overflow chamber.

Further, the control valve is a capillary passive valve.

Further, the second fluid channel is in the form of a siphon pipe, and one end of the siphon pipe is communicated with the fluid outlet.

Further, the part of the siphon pipe closest to the axis is radially outward relative to the position of the overflow outlet or the first fluid passage or the overflow inlet.

Further, the control valve is a second siphon pipe, and the part of the second siphon pipe closest to the axial center is radially inward with respect to the position of the overflow outlet or the first fluid passage or the overflow inlet.

Further, the second siphon pipe is made of hydrophilic material or treated with hydrophilicity.

Further, the second channel is arranged at the top of the measuring chamber, the control valve is a third siphon pipe, and the part of the third siphon pipe closest to the axis is relative to the overflow outlet or the first fluid channel or the overflow inlet. The location is radially inward.

Further, the measuring chamber, the first fluid channel and the overflow chamber are all arranged on a reagent disk that can be rotated by a driving device.

Further, the control valve adopts hydrophobic material or performs hydrophobic treatment for the second fluid channel.

The positive effect of the utility model is: under the action of centrifugal force, the utility model can fill the measuring chamber with the liquid entering from the inlet channel, the excess liquid enters the overflow chamber, and then controls the valve to open, so that all the liquid in the measuring chamber can be filled. Discharge, but the liquid in the overflow chamber will not be discharged, and the function of quantitative and then transfer of the liquid in the entire measuring chamber volume can be realized. At the same time, due to the structure of the present invention, there is no or only a small compressible medium in the overflow chamber to be compressed to achieve the function of liquid transport, and the volume of the overflow chamber is small.

Description of drawings

1 is a schematic structural diagram of Embodiment 1 of the present utility model;

2 is a schematic structural diagram of Embodiment 2 of the present utility model;

3 is a schematic structural diagram of Embodiment 3 of the present utility model;

FIG. 4 is a schematic structural diagram of Embodiment 4 of the present invention.

Detailed ways

First of all, it should be noted that, in the following description, the bottom indicates the side away from the rotation center of the reagent disk 9 , and the top indicates the side close to the rotation center of the reagent disk 9 . Both radially inner and radially outer are relative to the rotation axis of the reagent disk.

Embodiment 1: As shown in FIG. 1 , the present invention includes a rotatable reagent tray 9 , a measurement chamber 1 arranged on the reagent tray 9 , and an overflow chamber 2 communicated with the measurement chamber 1 through the first fluid channel 3 . , a fluid outlet 6 arranged at the bottom of the measurement chamber 1, a second fluid channel 5 communicating with the fluid outlet 6, and a second channel 7 for communicating the overflow chamber 2 with the atmosphere, the second fluid channel 5 is provided with Control valve, the control valve is a capillary passive valve. When the control valve is triggered, the liquid in the measurement chamber 1 is discharged through the fluid outlet 6. The top of the measurement chamber 1 is provided with an inlet channel 4 and an overflow outlet 10. In the overflow chamber There is an overflow inlet 11 at the top of the 1 , and both ends of the first fluid channel 3 are communicated with the overflow outlet 10 and the overflow inlet 11 respectively.

Preferably, the reagent disk 9 is circular, and rotates with the center of the circle as the axis, but of course other shapes can also be used. For the structure for driving the rotation of the reagent disk 9, a traditional centrifugal rotor or CD/DVD drive with adjustable rotational speed can be used, and other structures can also be used, as long as the rotation of the reagent disk 9 can be achieved so that the liquid on the reagent disk 9 can generate centrifugal force.

When the reagent disc 9 rotates, the liquid in the inlet channel 4 enters the measurement chamber 1 under the action of centrifugation, until the measurement chamber 1 is completely filled, and part of the liquid enters the overflow chamber 2 through the first fluid channel 3. The liquid in the flow chamber 2 is located at the bottom of the overflow chamber 2 under centrifugal action, and is separated from the liquid in the measurement chamber 50, and the amount of liquid entering from the inlet channel 4 is controlled so that the liquid level in the overflow chamber 2 is lower than The connection between the second channel 7 and the overflow chamber 2 is such that no compressible medium in the overflow chamber 2 is compressed. During the filling process of the measuring chamber 1, due to the action of the capillary passive valve, a capillary force opposite to the centrifugal force is generated in the second fluid channel 5, and the capillary force is greater than the centrifugal force, preventing the liquid from passing through the second fluid channel 5 The liquid that has entered the measurement chamber 1 is thus temporarily stored in the measurement chamber 1 . Then the rotation speed of the reagent plate 9 is driven to increase. When the centrifugal force of the liquid in the second fluid channel 5 is greater than the capillary force, all the liquid temporarily stored in the measurement chamber 1 will be transported out through the second fluid channel 5, so as to realize the quantification of the liquid, and The acceleration time of the reagent disk 9 can be adjusted to achieve the discharge of the liquid at a specific point in time.

The capillary passive valve can adopt the following structure, which includes at least a part, so that the inner dimension of the second fluid channel 5 has a sudden change (not shown in the figure), for example, the inner dimension of a certain part of the second fluid channel 5 suddenly increases. Alternatively, the second fluid channel 5 can be treated with hydrophobicity or a hydrophobic material can be used, and a valve with similar function can also be formed.

Embodiment 2: As shown in FIG. 2 , on the basis of Embodiment 1, other structures are kept unchanged, and the structure of the second fluid channel 5 is changed. The second fluid channel 5 adopts the structure of a siphon pipe 8 . One end of the siphon pipe 8 is communicated with the fluid outlet 6 , and the curved portion thereof is located on the side close to the rotation center of the reagent disk 9 . The part of the siphon pipe 8 closest to the axis is radially outward relative to the position of the overflow outlet 10 or the first fluid channel 3 or the overflow inlet 11 (that is, the minimum distance between the siphon pipe 8 and the axis of rotation of the reagent disk). greater than the distance between the overflow outlet 10 or the first fluid channel 3 or the overflow inlet 11 and the rotation axis of the reagent disc), that is, the distance between the overflow outlet 10 and the axis is smaller than the minimum distance between the siphon pipe 8 and the rotation axis , the first fluid channel 3 and the overflow inlet 11 are the same. The control valve located in the second fluid passage may be arranged in a relatively inner part of the siphon duct 8 . When the liquid flowing from the fluid outlet 6 enters the siphon pipe 8 , it first needs to flow along the siphon pipe 8 toward the side of the rotation center until it hits the control valve arranged on the siphon pipe 8 . This reduces the liquid level difference between the top of the liquid in the entire structure and the liquid in the siphon 8, further reducing the centrifugal force. This makes the valve located on the siphon line easier to implement.

Example 3: As shown in Figure 3, on the basis of Example 1, other structures remain unchanged, and the control valve is changed to the form of a second siphon pipe 12, one end of the second siphon pipe 12 is connected to the second fluid channel 5. connected. The part of the second siphon pipe 12 closest to the axis is radially inward with respect to the position of the overflow outlet 10 or the first fluid channel 3 or the overflow inlet 11, that is, the minimum distance between the second siphon pipe 12 and the rotation axis is smaller than the overflow outlet 10 or the first fluid channel 3 or the overflow inlet 11. The distance between the outflow port 10 and the rotation axis is the same as that of the first fluid channel 3 and the overflow inlet 11 . The second siphon pipe 12 is made of a hydrophilic material or subjected to hydrophilic treatment.

At the beginning, the reagent disc 9 is at a high speed, and the speed is generally greater than 50 rpm. Under the rotation of the reagent disc 9, the liquid enters the measuring chamber 1 until part of the liquid enters the overflow chamber 2, at which time it overflows The liquid in the chamber 2 is located at the bottom of the overflow chamber 2 under the action of centrifugation, and is separated from the liquid in the measuring chamber 50, and the amount of liquid entering the inlet channel 4 is controlled, so that the liquid level in the overflow chamber 2 is lower than the second. The connection between the channel 7 and the overflow chamber 2, so that no compressible medium is compressed in the overflow chamber 2. At this time, the liquid flowing into the measurement chamber is temporarily stored in the measurement chamber 1, and the centrifugal force is greater than that of the second siphon pipe 12. Capillary force, the liquid will not flow out from the second siphon pipe 12 . When the rotation speed of the reagent plate 9 decreases, the centrifugal force decreases until the capillary force is greater than the centrifugal force. Due to the capillary force, the liquid climbs over the part of the second siphon pipe 12 closest to the rotation axis and continues to flow away from the rotation axis , then due to the siphon effect, the liquid in the measuring chamber 1 is transported out.

When the liquid level in the overflow chamber 2 is higher than the second channel 7, part of the compressible medium (in this embodiment, gas) in the overflow chamber 2 is compressed. When the rotation speed of the reagent disc 9 is reduced, the compressed medium in the overflow chamber 2 expands, thereby transporting the liquid in the measuring chamber 1 to the second siphon pipe 12 until the liquid passes through the second siphon pipe 12 and is closest to the rotation center Then, due to the siphon effect, all the liquid in the measuring chamber 1 is transported out through the second siphon pipe. It can be seen from this that when more liquid is added from the inlet channel 4, so that the liquid level in the overflow chamber 2 is located above the connection between the second channel 7 and the overflow chamber 2, the second siphon pipe 12 can No hydrophilic treatment was performed.

Example 4: As shown in Figure 4, on the basis of Example 3, the second channel 7 is connected to the top of the measurement chamber 1, the inner diameter of the second channel 7 is smaller, and the second fluid channel 5 is connected at the same time. The other structures of the third siphon pipe 13 without hydrophilic treatment remain unchanged.

With this structure, when the liquid enters the overflow chamber 2, part of the compressible medium in the overflow chamber 2 is compressed, and when the rotation speed of the reagent disc 9 decreases, the compressed compressible medium in the overflow chamber 2 expands, thereby The liquid in the measuring chamber 1 is transported into the third siphon pipe 13 until the liquid passes through the part of the third siphon pipe 13 that is closest to the center of rotation, then due to the siphon effect, all the liquid in the measuring chamber 1 passes through the third siphon pipe 13 was sent out. In this process, due to the small inner diameter of the second channel 7 , the speed of gas discharge from the second channel 7 is also slow, and the gas expansion mainly acts to press the liquid in the measuring chamber 2 into the third siphon 13 . With the structure of this embodiment, the compressed gas in the overflow chamber 2 only needs to press the liquid in the measuring chamber 1 through the part of the third siphon pipe 13 that is closest to the rotation axis, and the requirements for the amount of compressed gas are relatively low. Therefore, the volume of the overflow chamber 2 can be kept small, so as to reduce the area of the overflow chamber 2 and improve the overall utilization rate of the reagent tray 9 .

The above embodiments are only used to illustrate the technical solutions of the present invention, but not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that the foregoing embodiments can still be used for The recorded technical solutions are modified, or some technical features thereof are equivalently replaced; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions in the embodiments of the present invention.

Claims (10)

1. A centrifugal force-based liquid quantitative transfer device is characterized by comprising a measuring chamber (1), an overflow chamber (2) communicated with the measuring chamber (1) through a first fluid channel (3), a fluid outlet (6) arranged at the outer side end of the measuring chamber (1), a second fluid channel (5) communicated with the fluid outlet (6) and a second channel (7) used for communicating the measuring chamber (1) or the overflow chamber (2) with the atmosphere, a control valve is arranged on the second fluid channel (5), when the control valve is triggered, the liquid in the measuring chamber (1) is discharged through a fluid outlet (6), the top of the measuring chamber (1) is provided with an inlet channel (4) and an overflow outlet (10), an overflow inlet (11) is arranged on the overflow chamber (2), and two ends of the first fluid channel (3) are respectively communicated with the overflow outlet (10) and the overflow inlet (11).

2. A centrifugal force based quantitative liquid transfer device according to claim 1, characterized in that the second channel (7) is arranged on the overflow chamber (2).

3. The device for quantitatively transferring liquid based on centrifugal force according to claim 2, wherein the control valve is a capillary passive valve.

4. A centrifugal force based quantitative liquid transfer device according to claim 3, characterized in that the second fluid channel (5) takes the form of a siphon (8), one end of the siphon (8) being in communication with the fluid outlet (6).

5. A centrifugal force based quantitative liquid transfer device according to claim 4, characterized in that the portion of the siphon channel (8) closest to the axial center is located radially outward with respect to the location of the overflow outlet (10) or the first fluid channel (3) or the overflow inlet (11).

6. A centrifugal force based quantitative liquid transfer device according to claim 2, wherein the control valve is a second siphon pipe (12), and the portion of the second siphon pipe (12) nearest to the axial center is radially inward with respect to the position of the overflow outlet (10) or the first fluid channel (3) or the overflow inlet (11).

7. A centrifugal force based quantitative liquid transfer device according to claim 6, characterized in that the second siphon (12) is made of hydrophilic material or treated with hydrophilic treatment.

8. A centrifugal force based quantitative liquid transfer device according to claim 1, characterized in that the second channel (7) is arranged at the top of the measuring chamber (1), the control valve is a third siphon (13), and the part of the third siphon (13) closest to the axial center is radially inward with respect to the position of the overflow outlet (10) or the first fluid channel (3) or the overflow inlet (11).

9. A centrifugal force based quantitative liquid transfer device according to claim 1, wherein the measuring chamber (1), the first fluid channel (3) and the overflow chamber (2) are all arranged on a reagent disk (9) which is rotatable by a driving means.

10. A centrifugal force based quantitative liquid transfer device according to claim 2, wherein the control valve is made of hydrophobic material or treated with hydrophobic property for the second fluid channel (5).

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