CN109796355A - A kind of preparation method of the threonine chelated zinc of feed - Google Patents
A kind of preparation method of the threonine chelated zinc of feed Download PDFInfo
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- CN109796355A CN109796355A CN201711148259.0A CN201711148259A CN109796355A CN 109796355 A CN109796355 A CN 109796355A CN 201711148259 A CN201711148259 A CN 201711148259A CN 109796355 A CN109796355 A CN 109796355A
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- zinc
- threonine
- chelated zinc
- preparation
- feed
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- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 title claims abstract description 40
- 239000004473 Threonine Substances 0.000 title claims abstract description 40
- 229940038879 chelated zinc Drugs 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims abstract description 16
- 238000001035 drying Methods 0.000 claims abstract description 15
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims abstract description 13
- 239000007864 aqueous solution Substances 0.000 claims abstract description 9
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims abstract description 9
- 229960001763 zinc sulfate Drugs 0.000 claims abstract description 9
- 229910000368 zinc sulfate Inorganic materials 0.000 claims abstract description 9
- 235000011121 sodium hydroxide Nutrition 0.000 claims abstract description 8
- 238000006243 chemical reaction Methods 0.000 claims abstract description 6
- 238000000926 separation method Methods 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract 2
- 239000000376 reactant Substances 0.000 claims description 5
- 230000035484 reaction time Effects 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 4
- 229910021529 ammonia Inorganic materials 0.000 claims description 2
- WQSRXNAKUYIVET-UHFFFAOYSA-N sulfuric acid;zinc Chemical compound [Zn].OS(O)(=O)=O WQSRXNAKUYIVET-UHFFFAOYSA-N 0.000 claims 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 17
- 239000011701 zinc Substances 0.000 abstract description 17
- 229910052725 zinc Inorganic materials 0.000 abstract description 17
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract description 6
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 238000000034 method Methods 0.000 abstract description 5
- 239000011573 trace mineral Substances 0.000 abstract description 5
- 235000013619 trace mineral Nutrition 0.000 abstract description 5
- 102000002260 Alkaline Phosphatase Human genes 0.000 abstract description 3
- 108020004774 Alkaline Phosphatase Proteins 0.000 abstract description 3
- 102000003846 Carbonic anhydrases Human genes 0.000 abstract description 3
- 108090000209 Carbonic anhydrases Proteins 0.000 abstract description 3
- 101710088194 Dehydrogenase Proteins 0.000 abstract description 3
- 102000004190 Enzymes Human genes 0.000 abstract description 3
- 108090000790 Enzymes Proteins 0.000 abstract description 3
- 102000004877 Insulin Human genes 0.000 abstract description 3
- 108090001061 Insulin Proteins 0.000 abstract description 3
- 230000023852 carbohydrate metabolic process Effects 0.000 abstract description 3
- 150000001720 carbohydrates Chemical class 0.000 abstract description 3
- 239000000470 constituent Substances 0.000 abstract description 3
- 229940125396 insulin Drugs 0.000 abstract description 3
- 230000037356 lipid metabolism Effects 0.000 abstract description 3
- 230000001737 promoting effect Effects 0.000 abstract description 3
- 230000022558 protein metabolic process Effects 0.000 abstract description 3
- 102000004169 proteins and genes Human genes 0.000 abstract description 3
- 108090000623 proteins and genes Proteins 0.000 abstract description 3
- 230000029663 wound healing Effects 0.000 abstract description 3
- 239000003674 animal food additive Substances 0.000 abstract description 2
- 210000004400 mucous membrane Anatomy 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 6
- 230000006870 function Effects 0.000 description 5
- 239000013522 chelant Substances 0.000 description 3
- 230000036039 immunity Effects 0.000 description 3
- 150000003839 salts Chemical group 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- 235000009967 Erodium cicutarium Nutrition 0.000 description 1
- 240000003759 Erodium cicutarium Species 0.000 description 1
- 206010053759 Growth retardation Diseases 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 1
- 206010044278 Trace element deficiency Diseases 0.000 description 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 230000008827 biological function Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 235000020774 essential nutrients Nutrition 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 239000011790 ferrous sulphate Substances 0.000 description 1
- 235000003891 ferrous sulphate Nutrition 0.000 description 1
- 231100000001 growth retardation Toxicity 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- BAUYGSIQEAFULO-UHFFFAOYSA-L iron(2+) sulfate (anhydrous) Chemical compound [Fe+2].[O-]S([O-])(=O)=O BAUYGSIQEAFULO-UHFFFAOYSA-L 0.000 description 1
- 229910000359 iron(II) sulfate Inorganic materials 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 229940029985 mineral supplement Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000019629 palatability Nutrition 0.000 description 1
- -1 phytate anion Chemical class 0.000 description 1
- 235000002949 phytic acid Nutrition 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
Landscapes
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a kind of feed preparation method of threonine chelated zinc, this method belongs to feed additive field, and producing the raw material that the product uses includes: threonine, zinc sulfate, 10% sodium hydrate aqueous solution；Product is made by techniques such as the chelatropic reaction of the production of aqueous solution, threonine and zinc sulfate, separation drying, technological advantage is: the threonine chelated zinc of industrialized production, simple process, manufacturing cost is low, easy to operate without increasing important equipment, easy to spread；Trace element zinc is the constituent of a variety of enzymes such as carbonic anhydrase, alkaline phosphatase, lactic dehydrogenase, and in conjunction with insulin, zinc plays a significant role in protein, carbohydrate and lipid metabolism, zinc is to maintain skin, the normal configuration of mucous membrane and function and the necessary factor for promoting wound healing again, and zinc and threonine chelated rear animal absorptivity greatly increase.
Description
Technical field
The invention belongs to feed additive fields, and in particular to a kind of preparation method of the threonine chelated zinc of feed.
Background technique
Microelement is one of essential nutrient during growth of animal, and initial microelement is with inorganic salts
Form is introduced directly into feed, such as ferrous sulfate, although inorganic salts are water-soluble very well, in animal alimentary canal easily with feeding
Common phytate anion, oxalate anion form corresponding solubility very little by the intracorporal biochemical reaction form of animal in material
Salt, be not easy by intestinal absorption.With the development of feed industry, trace mineral supplement amino-acid trace element chelate etc. is gradually
It is developed, its feature is stable, efficient, small toxicity, and the absorption easy to digest in enteron aisle is conducive to growth of animal, energy
Prevent and treat trace element deficiency, improve the immunity of organisms of animal, and in feed nutrition composition using beneficial, it is also simultaneous
There is high-protein agent.The present invention is the chelate of threonine and zinc, and threonine is second or the third limitation of livestock and poultry
Acidic amino acid, have promote growth, improve immunity function, lack threonine, can lead to animal feed intake reduction, growth retardation,
Efficiency of feed utilization decline, immunity function such as inhibit at the symptoms, and threonine is that animal itself cannot synthesize, but highly desirable ammonia
Base acid, can only be entered in animal body by feed, and addition threonine also can reduce tryptophan or the excessive caused growth of methionine
Inhibit.The biological function of trace element zinc is of crucial importance and complicated, and zinc is carbonic anhydrase, alkaline phosphatase, lactic dehydrogenase
Etc. the constituent of a variety of enzymes, and in conjunction with insulin, so, zinc is sent out in protein, carbohydrate and lipid metabolism
Important function is waved, zinc is to maintain skin, the normal configuration of mucous membrane and function and the necessary factor for promoting wound healing again, and zinc lacks
Reactive volt-ampere hour, pig show as slow growth, and secondary dermatitis, less and a small, the boar testis of sow pig farrowing occur for the incomplete keratinization of skin
Ball impaired development, the generation of sperm and motility reduce；There are crowfoot cracks in the breast and four limbs of milk cow；Dermatitis and plumage occur for poultry
Hair lacks, therefore zinc is one of indispensable microelement in animal feed, and zinc and threonine chelated rear animal absorptivity are big
It is big to increase.
Summary of the invention
Present invention mainly solves the problem of be to provide a kind of chelate with threonine and zinc, produce the original that the product uses
Material includes: threonine, zinc sulfate, 10% sodium hydrate aqueous solution.
The present invention can be achieved through the following technical solutions:
A kind of preparation method of the threonine chelated zinc of feed, it is characterized in that being made of following steps:
(1) threonine: zinc sulfate: the ratio of water 20-22:10:68-70 in molar ratio is sent into chemical reaction kettle, keeps normal
Temperature starts blender, monitors pH value at any time, is 7.0-7.2, reaction time 0.8-1.0 with 10% sodium hydrate aqueous solution tune pH value
Hour.
(2) reactant is sent into centrifugal separator separation, removing the solid obtained after moisture removal is threonine chelated zinc, will be revived
Propylhomoserin chelated zinc obtains finished product after being sent into drying machine sealing drying 1.0-1.2 hours.
Threonine purity described in above-mentioned steps (1) is 90%.
Zinc sulfate purity described in above-mentioned steps (1) is 85%.
The drying temperature of drying machine described in above-mentioned steps (2) is 50 DEG C -60 DEG C.
The beneficial effects of the present invention are:
(1) the threonine chelated zinc of industrialized production, simple process, manufacturing cost is low, easy to operate without increasing important equipment,
It is easy to spread；
(2) the feed palatability of product configuration is good, and absorptivity is high, easily transports, and threonine chelated zinc fills the effect of growth of animal
Get performance, trace element zinc is the constituent of a variety of enzymes such as carbonic anhydrase, alkaline phosphatase, lactic dehydrogenase, and
In conjunction with insulin, zinc plays a significant role in protein, carbohydrate and lipid metabolism, and zinc is to maintain skin, stick again
The normal configuration and function of film and the necessary factor for promoting wound healing, zinc and threonine chelated rear animal absorptivity increase
Add.
Specific embodiment
Below with reference to specific embodiment, the present invention is described in further detail.
Embodiment 1
Threonine: zinc sulfate: water in molar ratio 20:10:70 ratio be sent into chemical reaction kettle, the temperature remains within the normal range, starts stirring
Device monitors pH value at any time, with 10% sodium hydrate aqueous solution tune pH value be 7.0, the reaction time 0.8 hour；By reactant be sent into from
Centrifugal separator separation, removing the solid obtained after moisture removal is threonine chelated zinc, and threonine chelated zinc is sent into drying machine sealing
Drying obtained finished product after 1.0 hours.
Embodiment 2
Threonine: zinc sulfate: water in molar ratio 21:10:69 ratio be sent into chemical reaction kettle, the temperature remains within the normal range, starts stirring
Device monitors pH value at any time, with 10% sodium hydrate aqueous solution tune pH value be 7.1, the reaction time 0.9 hour；By reactant be sent into from
Centrifugal separator separation, removing the solid obtained after moisture removal is threonine chelated zinc, and threonine chelated zinc is sent into drying machine sealing
Drying obtained finished product after 1.1 hours.
Embodiment 3
Threonine: zinc sulfate: water in molar ratio 22:10:68 ratio be sent into chemical reaction kettle, the temperature remains within the normal range, starts stirring
Device monitors pH value at any time, with 10% sodium hydrate aqueous solution tune pH value be 7.2, the reaction time 1.0 hours；By reactant be sent into from
Centrifugal separator separation, removing the solid obtained after moisture removal is threonine chelated zinc, and threonine chelated zinc is sent into drying machine sealing
Drying obtained finished product after 1.2 hours.
Claims (4)
1. a kind of feed preparation method of threonine chelated zinc, producing the raw material that the product uses includes: threonine, sulfuric acid
Zinc, 10% sodium hydrate aqueous solution；Its feature the following steps are included:
(1) threonine: zinc sulfate: the ratio of water 20-22:10:68-70 in molar ratio is sent into chemical reaction kettle, keeps normal
Temperature starts blender, monitors pH value at any time, is 7.0-7.2, reaction time 0.8-1.0 with 10% sodium hydrate aqueous solution tune pH value
Hour；
(2) reactant is sent into centrifugal separator separation, removing the solid obtained after moisture removal is threonine chelated zinc, by threonine
Chelated zinc obtains finished product after being sent into drying machine sealing drying 1.0-1.2 hours.
2. the preparation method of the threonine chelated zinc of a kind of feed according to claim 1, it is characterized in that: Soviet Union's ammonia
Sour purity is 90%.
3. the preparation method of the threonine chelated zinc of a kind of feed according to claim 1, it is characterized in that: the sulfuric acid
Zinc purity is 85%.
4. the preparation method of the threonine chelated zinc of a kind of feed according to claim 1, it is characterized in that: the drying
The drying temperature of machine is 50 DEG C -60 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711148259.0A CN109796355A (en) | 2017-11-17 | 2017-11-17 | A kind of preparation method of the threonine chelated zinc of feed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711148259.0A CN109796355A (en) | 2017-11-17 | 2017-11-17 | A kind of preparation method of the threonine chelated zinc of feed |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109796355A true CN109796355A (en) | 2019-05-24 |
Family
ID=66554975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711148259.0A Withdrawn CN109796355A (en) | 2017-11-17 | 2017-11-17 | A kind of preparation method of the threonine chelated zinc of feed |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109796355A (en) |
-
2017
- 2017-11-17 CN CN201711148259.0A patent/CN109796355A/en not_active Withdrawn
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20190524 |
|
| WW01 | Invention patent application withdrawn after publication |