CN109316589A - A kind of drug and preparation method thereof for treating stomach trouble - Google Patents
A kind of drug and preparation method thereof for treating stomach trouble Download PDFInfo
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- CN109316589A CN109316589A CN201811428070.1A CN201811428070A CN109316589A CN 109316589 A CN109316589 A CN 109316589A CN 201811428070 A CN201811428070 A CN 201811428070A CN 109316589 A CN109316589 A CN 109316589A
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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Abstract
The invention discloses a kind of drugs for treating stomach trouble, drug materials used are all pure natural medicinal materials, it is without side-effects, securely and reliably, relative to other Chinese medicines, the amount of effective component possessed by golden freeze-dried powder is more than the effective component of other Chinese medicinal materials in dove stomach freeze-dried powder and dove, in addition with the cooperation of Chinese medicinal material, and extracting solution is made by repeatedly decocting in Chinese medicine, the present invention works very fast with respect to pure Chinese medicinal preparation；For the present invention according to theory of traditional Chinese medical science essence, provided Chinese herbal medicine compatibility is reasonable, it is warm-natured and, to the burden of human body without or it is few, be suitble to extensive crowd to use.And preparation method is simple for the drug for the treatment of stomach trouble provided by the present invention, not only can mass production, but also can voluntarily prepare use, greatly reduce the treatment cost of patient.
Description
Technical field
The present invention relates to pharmaceutical technology field, in particular to a kind of drug and preparation method thereof for treating stomach trouble.
Background technique
Stomach trouble is a kind of common frequently-occurring disease, but is also the persistent ailment that the mankind can not thoroughly eradicate always.It is each currently on the market
The drug of kind various kinds treatment stomach trouble, including Western medicine and Chinese patent drug.Western medicine curative effect is single, expensive, and side effect is big, some patients
It will appear adverse reaction；And although Chinese patent drug plays certain gastrotherapy effect, but preparation process is cumbersome, limited efficacy, no
Only slow effect, and recurrence is easy after treating.
Therefore, how to provide that a kind of drug effect is significant, the drug for the treatment of stomach trouble quick and have no toxic side effect is this field
Technical staff's urgent problem to be solved.
Summary of the invention
In view of this, the present invention provides a kind of drugs and preparation method thereof for treating stomach trouble.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: golden in 10~20 parts of dove stomach freeze-dried powder, dove
1~10 part of freeze-dried powder, 5~15 parts of fingered citron, 5~10 parts of Fructus Hordei Germinatus, 5~15 parts of Poria cocos, 1~5 part of fructus amomi, 3~12 parts of cloves, meat
5~10 parts of cardamom, 5~15 parts of Rhizoma Dioscoreae, 10~15 parts of blood clam, 10~20 parts of rde bean, 1~10 part of rhizoma zingiberis.
Preferably, a kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: dove stomach freeze-dried powder 12~20
Part, golden 2~6 parts of freeze-dried powder, 8~12 parts of fingered citron, 5~8 parts of Fructus Hordei Germinatus, 8~12 parts of Poria cocos, 3~5 parts of fructus amomi, cloves 5 in dove~
10 parts, 5~8 parts of nutmeg, 8~12 parts of Rhizoma Dioscoreae, 10~12 parts of blood clam, 15~20 parts of rde bean, 2~6 parts of rhizoma zingiberis.
Preferably, a kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: 15 parts of dove stomach freeze-dried powder, dove
Interior gold 4 parts of freeze-dried powder, 10 parts of fingered citron, 6 parts of Fructus Hordei Germinatus, 10 parts of Poria cocos, 4 parts of fructus amomi, 6 parts of cloves, 6 parts of nutmeg, Rhizoma Dioscoreae 10
Part, 10 parts of blood clam, 15 parts of rde bean, 4 parts of rhizoma zingiberis.
Preferably, in a kind of above-mentioned drug for treating stomach trouble, the drug effect of various Chinese medicines are as follows:
Dove stomach freeze-dried powder: promoting qi circulation and relieving pain, clearing damp resolving sputum, warm-natured, returns spleen, stomach promote WeiDongLi Capsule, except gasteremphraxis, help digestion.
Golden freeze-dried powder in dove: stomach strengthening and digestion promoting, arresting seminal emission.For dyspepsia, vomiting dysentery, infantile malnutrition, the enuresis, something lost
Essence, anticancer, anti-cancer.
Fingered citron: root, stem, leaf, flower, fruit can be used as medicine, pungent, bitter, sweet, warm, nontoxic；Enter liver, spleen, stomach three to pass through, reasonable gasification
A variety of medicinal functions such as phlegm, preventing or arresting vomiting dissipate-swelling, liver soothing and speen fortifying, stomach function regulating.There is apparent alleviate to make tracheitis, the asthma of the elderly
With；And to the indigestion of common people, that chest and abdomen are swollen is bored, have significantly more curative effect.Fingered citron can be made into several kinds of Chinese medicinal materials, long term usage
There is health-care.
Fructus Hordei Germinatus: promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, moves back newborn dissipate-swelling.
Poria cocos: clearing damp and promoting diuresis, invigorating the spleen, calming heart.
Fructus amomi: acrid flavour is warm-natured, returns spleen, stomach, kidney channel, can dampness elimination appetizing, warming spleen and stopping diarrha, regulating the flow of vital energy and preventing miscarriage etc..It is usually used in wet turbid
Middle resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting and diarrhea, hyperemesis gravidarum, threatened abortion etc..Especially to superficial gastritis, duodenum
Ulcer, gasteremphraxis stomachache have special efficacy.It is usually often edible then to have nourishing stomach and spleen, warm up lung health-care effect kidney nourishing.
Nutmeg: its kernel is used as medicine, and can be controlled void and be rushed down cold dysentery, coldness and pain in the epigastrium, vomiting etc.；External application can make helminth expellent,
Treat rheumatalgia etc..
Rhizoma Dioscoreae: mending without stagnant, not hot not dry, can enriching spleen-QI and beneficial stomach-Yin.
Blood clam: resolving sputum, softening hard masses dissipate the stasis of blood, disperse accumulation.Control phlegm product, stomachache, noisy, acid regurgitation, abdominal mass, scrofula, noma.
Rde bean: being mainly used for Chinese medicine, often mixed with red bean, has inducing diuresis for removing edema, removing toxic substances apocenosis and other effects.
Rhizoma zingiberis: middle benefit gas is by cold, recover Yang and smooth venation.Trusted subordinate's crymodynia is controlled, is vomited and diarrhoea, cold weak pulse of limb is breathed with cough for cold time, wind-cold-dampness arthralgia, sun
Void spits, is defeated in battle, lower blood.
By using above-mentioned technical proposal, beneficial effects of the present invention are as follows:
The materials of drug used in the present invention are all pure natural medicinal materials, without side-effects, securely and reliably, relative to other Chinese medicines,
The amount of effective component possessed by golden freeze-dried powder is more than the effective component of other Chinese medicinal materials in dove stomach freeze-dried powder and dove, in addition
With the cooperation of Chinese medicinal material, and Chinese medicine by repeatedly decoct be made extracting solution, the present invention with respect to pure Chinese medicinal preparation work comparatively fast；
For the present invention according to theory of traditional Chinese medical science essence, provided Chinese herbal medicine compatibility is reasonable, it is warm-natured and, to the burden of human body without or it is few, fit
It closes extensive crowd to use, the Chinese herbal medicine in prescription, which is used cooperatively, both can effectively treat the diseases such as spleen and stomach function disorder, lifting imbalance
Disease, and human-body viscera function can be improved, while mitigating and reducing the impaired complication deteriorated of spleen and gastrointestinal tract function, and
Various stomach can be treated, the stomach medicine is not only cheap, Small side effects, and therapeutic effect is significant, and patient is uneasy to recur.Cause
This, invention can be widely used in the long-term treatment of stomach trouble, and not only application method is easy, but also stomachache, gastric acid, stomach is effectively relieved
The diseases such as swollen, gastric ulcer, significant in efficacy, great market application and promotional value.
Preferably, in the dove stomach freeze-dried powder and dove golden freeze-dried powder be by microwave vacuum puffing dry, freezing processing and
The partial size that ultramicro grinding step obtains is in 20 μm of ultra-micro powders below.
It is another object of the present invention to provide a kind of preparation methods of drug for treating stomach trouble.
To achieve the goals above, technical scheme is as follows:
A kind of preparation method of drug that treating stomach trouble, the method specifically includes the following steps:
Step 1: golden freeze-dried powder in preparation dove stomach freeze-dried powder and dove
(1) gold in good dove stomach and dove is selected, is dried to water content between 30~35% after cleaning slice, it is spare；
(2) will to carry out microwave vacuum puffing by gold in above-mentioned steps treated dove stomach and dove dry, and will carry out micro-
In dove stomach and dove after the vacuum puffed drying of wave gold respectively by crushing in advance, freezing processing and pulverize step after to get
Golden freeze-dried powder, spare in dove stomach freeze-dried powder and dove；
Step 2: preparation traditional Chinese medicine powder
(1) weigh respectively in parts by weight fingered citron, Fructus Hordei Germinatus, Poria cocos, fructus amomi, cloves, nutmeg, Rhizoma Dioscoreae, blood clam,
Rde bean and rhizoma zingiberis, mix, and obtain mixture；
(2) filter residue in the step (1) is added dehydrated alcohol and filters after being heated to reflux 20-40 minutes, obtains second
Filtrate and filter residue；
(3) filter residue obtained by the step (2) is rinsed with dehydrated alcohol, washing lotion is incorporated into the second filtrate, obtains third filtrate；
(4) the first filtrate that the step (1) obtains and the third filtrate that the step (3) obtains are merged, it is spraying dry
It is dry to obtain traditional Chinese medicine powder, it is spare；
Step 3: weighing in dove stomach freeze-dried powder made from step 1 and dove golden freeze-dried powder respectively in parts by weight, and by its
It is uniformly mixed with traditional Chinese medicine powder made from step 2, obtains mixed raw material powder；
Step 4: institute of the present invention is prepared using conventional drug tablet forming technique in the mixed raw material powder that step 3 obtains
A kind of disclosed drug for treating stomach trouble.
By using above-mentioned technical proposal, beneficial effects of the present invention are as follows:
The present invention cooperates by using unique microwave vacuum puffing dry technology to freeze, the technologies such as ultra micro, is prepared into
Golden freeze-dried powder quality is preferable in the dove stomach freeze-dried powder arrived and dove, has been sufficiently reserved the nutriture value of dove stomach and dove Nei Jinnei main component
Value, improves the utilization rate of raw material, and waste is few；Preparation method is simple for the drug for the treatment of stomach trouble provided by the present invention,
Not only can mass production, but also can voluntarily prepare use, greatly reduce the treatment cost of patient.
Preferably, in the step 1, the running parameter of microwave vacuum puffing drying process: pressure control -75~-
Between 80kPa, microwave intensity is controlled between 25~30W/g, and temperature controls between 65 DEG C~80 DEG C.
Preferably, in the step 2, the size controlling of traditional Chinese medicine powder is between 5~15 μm.
Preferably, the tabletting specification in the step 4 is that every tablet contains mixed raw material powder 0.3-0.5g.
The technical scheme is that applicant obtains by the clinic concentrated on studies more than the 30 years constantly practice of many years.
2 tablets once for this drug when taking, and brown sugar water takes, but should not drink more water and send.Three times a day, it takes within about 1 hour after the meal.3~4 weeks
For 1 course for the treatment of, children halve, and pregnant woman is used with caution.
It can be seen via above technical scheme that compared with prior art, the present invention provides a kind of drug for treating stomach trouble,
It is made by using pure natural herbal raw material through reasonable compatibility, both can effectively treat spleen and stomach function disorder, lifting imbalance
Etc. illnesss, and human-body viscera function can be improved, the symptom of stomach trouble is made to be eased and cure.The stomach medicine not only price
Cheap, Small side effects, therapeutic effect is significant, and patient is uneasy to recur.It invention can be widely used in the long-term treatment of stomach trouble, no
Only application method is easy, and the diseases such as stomachache, gastric acid, gasteremphraxis, gastric ulcer are effectively relieved, quick, significant in efficacy, great city
Field application and promotional value.
Specific embodiment
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment
Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
Art personnel every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
A kind of drug for treating stomach trouble disclosed in this invention, not only drug effect is significant, quick, but also has no toxic side effect,
Great market application and promotional value.
The invention discloses a kind of drugs for treating stomach trouble, are made of the raw material of following parts by weight:
Golden 1~10 part of freeze-dried powder, 5~15 parts of fingered citron, 5~10 parts of Fructus Hordei Germinatus, Poria cocos in 10~20 parts of dove stomach freeze-dried powder, dove
5~15 parts, it is 1~5 part of fructus amomi, 3~12 parts of cloves, 5~10 parts of nutmeg, 5~15 parts of Rhizoma Dioscoreae, 10~15 parts of blood clam, red
10~20 parts of red bean, 1~10 part of rhizoma zingiberis.
In order to further realize technical effect of the invention, golden freeze-dried powder is to pass through microwave in the dove stomach freeze-dried powder and dove
The partial size that vacuum puffed drying, freezing processing and ultramicro grinding step obtain is in 20 μm of ultra-micro powders below.
Invention additionally discloses a kind of preparation methods of drug for treating stomach trouble, specifically comprise the following steps:
Step 1: golden freeze-dried powder in preparation dove stomach freeze-dried powder and dove
(1) gold in good dove stomach and dove is selected, is dried to water content between 30~35% after cleaning slice, it is spare；
(2) will to carry out microwave vacuum puffing by gold in above-mentioned steps treated dove stomach and dove dry, and will carry out micro-
In dove stomach and dove after the vacuum puffed drying of wave gold respectively by crushing in advance, freezing processing and pulverize step after to get
Golden freeze-dried powder, spare in dove stomach freeze-dried powder and dove；
Step 2: preparation traditional Chinese medicine powder
(1) weigh respectively in parts by weight fingered citron, Fructus Hordei Germinatus, Poria cocos, fructus amomi, cloves, nutmeg, Rhizoma Dioscoreae, blood clam,
Rde bean and rhizoma zingiberis, mix, and obtain mixture；
(2) filter residue in step (1) is added dehydrated alcohol and filters after being heated to reflux 20-40 minutes, obtains the second filtrate
And filter residue；
(3) filter residue obtained by step (2) is rinsed with dehydrated alcohol, washing lotion is incorporated into the second filtrate, obtains third filtrate；
(4) the first filtrate that step (1) obtains and the third filtrate that step (3) obtains are merged, is spray-dried in obtaining
Medicinal powder, it is spare；
Step 3: weighing in dove stomach freeze-dried powder made from step 1 and dove golden freeze-dried powder respectively in parts by weight, and by its
It is uniformly mixed with traditional Chinese medicine powder made from step 2, obtains mixed raw material powder；
Step 4: institute of the present invention is prepared using conventional drug tablet forming technique in the mixed raw material powder that step 3 obtains
A kind of disclosed drug for treating stomach trouble.
In order to further realize technical effect of the invention, the work of the microwave vacuum puffing drying process in step 1 is joined
Number: pressure controls between -75~-80kPa, and microwave intensity controls between 25~30W/g, and temperature is controlled at 65 DEG C~80 DEG C
Between.
In order to further realize technical effect of the invention, the size controlling of the traditional Chinese medicine powder in step 2 5~15 μm it
Between.
In order to further realize technical effect of the invention, the tabletting specification in step 4 is that every tablet contains mixed raw material
Powder 0.3-0.5g.
Below in conjunction with specific embodiment, technical solution of the present invention is further detailed.
Embodiment 1:
A kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: gold freeze-drying in 18 parts of dove stomach freeze-dried powder, dove
2 parts of powder, 10 parts of fingered citron, 5 parts of Fructus Hordei Germinatus, 10 parts of Poria cocos, 1 part of fructus amomi, 4 parts of cloves, 9 parts of nutmeg, 6 parts of Rhizoma Dioscoreae, blood clam
10 parts, 12 parts of rde bean, 8 parts of rhizoma zingiberis.
Embodiment 2:
A kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: gold freeze-drying in 12 parts of dove stomach freeze-dried powder, dove
8 parts of powder, 6 parts of fingered citron, 8 parts of Fructus Hordei Germinatus, 6 parts of Poria cocos, 5 parts of fructus amomi, 10 parts of cloves, 5 parts of nutmeg, 10 parts of Rhizoma Dioscoreae, blood clam
10 parts, 12 parts of rde bean, 8 parts of rhizoma zingiberis.
Embodiment 3:
A kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: gold freeze-drying in 14 parts of dove stomach freeze-dried powder, dove
6 parts of powder, 6 parts of fingered citron, 9 parts of Fructus Hordei Germinatus, 10 parts of Poria cocos, 5 parts of fructus amomi, 10 parts of cloves, 5 parts of nutmeg, 10 parts of Rhizoma Dioscoreae, blood clam
10 parts, 13 parts of rde bean, 2 parts of rhizoma zingiberis.
Embodiment 4:
A kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: gold freeze-drying in 15 parts of dove stomach freeze-dried powder, dove
2 parts of powder, 8 parts of fingered citron, 6 parts of Fructus Hordei Germinatus, 10 parts of Poria cocos, 4 parts of fructus amomi, 4 parts of cloves, 6 parts of nutmeg, 10 parts of Rhizoma Dioscoreae, blood clam
10 parts, 16 parts of rde bean, 9 parts of rhizoma zingiberis.
Embodiment 5:
A kind of drug for treating stomach trouble, is made of the raw material of following parts by weight: gold freeze-drying in 16 parts of dove stomach freeze-dried powder, dove
4 parts of powder, 8 parts of fingered citron, 8 parts of Fructus Hordei Germinatus, 14 parts of Poria cocos, 1 part of fructus amomi, 4 parts of cloves, 5 parts of nutmeg, 10 parts of Rhizoma Dioscoreae, blood clam
10 parts, 11 parts of rde bean, 9 parts of rhizoma zingiberis.
In order to further verify the drug for the treatment of stomach trouble that the present invention is prepared with excellent property, inventor also into
Gone control experiment: embodiment 6 and embodiment 7 prepare composition of raw materials using disclosed by the invention, and comparative example 1, comparative example 2 are distinguished
It only deletes golden freeze-dried powder in dove stomach freeze-dried powder and dove on the basis of embodiment 6 and 7 to be compareed, the specific formula of above-mentioned each example
It is as shown in the table:
Table 1
| Embodiment 6 | Embodiment 7 | Comparative example 1 | Comparative example 2 | |
| Dove stomach freeze-dried powder | 15 | 12 | / | / |
| Golden freeze-dried powder in dove | 4 | 6 | / | / |
| Fingered citron | 10 | 5 | 10 | 5 |
| Fructus Hordei Germinatus | 6 | 5 | 6 | 5 |
| Poria cocos | 10 | 10 | 10 | 10 |
| Fructus amomi | 4 | 4 | 4 | 4 |
| Cloves | 6 | 8 | 6 | 8 |
| Nutmeg | 6 | 5 | 6 | 5 |
| Rhizoma Dioscoreae | 10 | 10 | 10 | 10 |
| Blood clam | 10 | 12 | 10 | 12 |
| Rde bean | 15 | 18 | 15 | 18 |
| Rhizoma zingiberis | 4 | 5 | 4 | 5 |
The drug of four kinds for the treatment of stomach trouble is prepared according to any preparation method of Examples 1 to 5 by upper table formula.
Next, the obtained drug of comparative example 1 and 2 does following tablet composition test experience respectively by embodiment 6 and 7,
Reference standard is the 7th part of YY/T 0188.7-1995 drug inspection operating instruction: medicinal chemicals content determination, test knot
Fruit is as follows:
By the above results analysis it is found that the effective ingredient content for the treatment stomach trouble that the embodiment of the present invention is prepared is high
And tablet composition is evenly distributed.Golden freeze-dried powder can make dove stomach and dove in ultra micro dove stomach freeze-dried powder that above-mentioned technique obtains and ultra micro dove
The cell-wall breaking ratio of interior gold is up to 95%, to improve the effective ingredient content of the tablet, considerably increases the absorption of human body
Dissolubility keeps obtained stomach medicine quick, significant in efficacy.And it, can since ultrafine powder and Chinese traditional powder partial size are smaller
Mobility and powder surface cohesion in raising stomach medicine tabletting preparation process is larger, and adsorptivity is preferable, and product quality is more
Stablize, the two is not easy to be layered after mixing, so that effective component in obtained stomach medicine tablet be made to be evenly distributed.
Clinical case
Volunteer is invited to carry out measure of merit to stomach medicine produced by the present invention at random first, 2 tablets once for this drug when taking,
Brown sugar water takes, but should not drink more water and send, and three times a day, takes within about 1 hour after the meal, and 3~4 weeks are 1 course for the treatment of, and measurement result is such as
Under:
1: Mr. Guo of case, 40 years old.Checked there is gastric ulcer and slight atrophic gastritis through hospital before 3 years, pain obtains nothing sometimes
Method is endured, and has been seen 2 years in hospital, changeable.In July, 2016 upon somebody's introduction, has taken stomach medicine of the invention, application method
It is delivered with water, every time 2-4 stomach medicine medicinal powder, 3 times a day, can all take before meals, after meal.3-4 weeks is 1 course for the treatment of.Same day analgesic.
Patient's inadaptation shape has a very big alleviation after one month, substantially the not no symptom of pain.After taking three courses for the treatment of, patient is not
It adapts to symptom to completely disappear, and the state of mind has been got well very much, physical strength also has enhancing.Follow-up did not occurred recurrence to current patient.
2: Mrs Wang of case, 35 years old.After having given birth to child, there is gastroenteritis for a long time, with regard to abdominal distension after having a meal, has a stomachache, less than
Half an hour must go to suffer from diarrhea.Having seen fast ten years in hospital can not all solve, and again and again, not cure.2017 through friend
It introduces, has taken stomach medicine of the invention.Three is as a treatment course to surrounding.After one course for the treatment of, the above symptom is disappeared.It is controlled to consolidate
It treats, she adheres to the edible tri course for the treatment of, to currently without any discomfort, does not also recur.When return visit, she indicates to thank very much.
3: Mr. He of case, 70 years old.It is examined through looking within 2014, for a long time with the routed gastric ulcer of stomach, and finds that stomach has black patch, cure
Raw say is likely to be stomach neoplasm, it is proposed that hospitalization.In order to save money, old man be unwilling to be hospitalized.Abdominal pain, midnight often wake up bitterly, often
Upper abdomen burns sample pain, often eats to hospital by medicine, but does not have positive effect, and analgesic Western medicine is often eaten.In April, 2015 starts to take
Stomach medicine of the invention.Application method is delivered with water, and 4 tablets once, 1-3 times daily, can all be taken before meals, after meal.It is treated for 1 within 3-4 weeks
Journey.After one course for the treatment of, malaise symptoms originally obtain very big alleviation, occur original pain never again, and spirit might as well
Very much, physical strength also enhances.After three courses for the treatment of, those former malaise symptoms disappear comprehensively, and spirit is more preferable, and physical strength is stronger.To the present
June in year pays a return visit, and patient does not have any discomfort, more do not recur.
By the above measurement result it is found that stomach medicine prepared by the present invention have the effect of in terms for the treatment of stomach trouble it is splendid, short
Disease symptoms can be made to be eased in period, and without recurrence after healing, efficacy stability is without dependence.
Each embodiment in this specification is described in a progressive manner, the highlights of each of the examples are with other
The difference of embodiment, the same or similar parts in each embodiment may refer to each other.For device disclosed in embodiment
For, since it is corresponded to the methods disclosed in the examples, so being described relatively simple, related place is said referring to method part
It is bright.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (8)
1. a kind of drug for treating stomach trouble, which is characterized in that be made of the raw material of following parts by weight:
Golden 1~10 part of freeze-dried powder, 5~15 parts of fingered citron, 5~10 parts of Fructus Hordei Germinatus, Poria cocos 5 in 10~20 parts of dove stomach freeze-dried powder, dove~
15 parts, 1~5 part of fructus amomi, 3~12 parts of cloves, 5~10 parts of nutmeg, 5~15 parts of Rhizoma Dioscoreae, 10~15 parts of blood clam, rde bean
10~20 parts, 1~10 part of rhizoma zingiberis.
2. a kind of drug for treating stomach trouble according to claim 1, which is characterized in that by the raw material group of following parts by weight
At:
Golden 2~6 parts of freeze-dried powder, 8~12 parts of fingered citron, 5~8 parts of Fructus Hordei Germinatus, Poria cocos 8~12 in 12~20 parts of dove stomach freeze-dried powder, dove
Part, 3~5 parts of fructus amomi, 5~10 parts of cloves, 5~8 parts of nutmeg, 8~12 parts of Rhizoma Dioscoreae, 10~12 parts of blood clam, rde bean 15
~20 parts, 2~6 parts of rhizoma zingiberis.
3. a kind of drug for treating stomach trouble according to claim 2, which is characterized in that by the raw material group of following parts by weight
At:
Golden 4 parts of freeze-dried powder, 10 parts of fingered citron, 6 parts of Fructus Hordei Germinatus, 10 parts of Poria cocos, 4 parts of fructus amomi, cloves 6 in 15 parts of dove stomach freeze-dried powder, dove
Part, 6 parts of nutmeg, 10 parts of Rhizoma Dioscoreae, 10 parts of blood clam, 15 parts of rde bean, 4 parts of rhizoma zingiberis.
4. according to claim 1~3 it is described in any item treatment stomach trouble drugs, which is characterized in that the dove stomach freeze-dried powder and
Golden freeze-dried powder is dry, freezing processing and to pulverize partial size that step obtains at 20 μm or less by microwave vacuum puffing in dove
Ultra-micro powder.
5. a kind of preparation method for the drug for treating stomach trouble, which is characterized in that the method specifically includes the following steps:
Step 1: golden freeze-dried powder in preparation dove stomach freeze-dried powder and dove
(1) gold in good dove stomach and dove is selected, is dried to water content between 30~35% after cleaning slice, it is spare；
(2) will to carry out microwave vacuum puffing by gold in above-mentioned steps treated dove stomach and dove dry, and it is true to carry out microwave
Gold is respectively by crushing in advance, after freezing processing and ultramicro grinding step to get dove stomach in dove stomach and dove after empty explosion puffing drying
Golden freeze-dried powder, spare in freeze-dried powder and dove；
Step 2: preparation traditional Chinese medicine powder
(1) fingered citron, Fructus Hordei Germinatus, Poria cocos, fructus amomi, cloves, nutmeg, Rhizoma Dioscoreae, blood clam, red small is weighed respectively in parts by weight
Beans and rhizoma zingiberis, mix, and obtain mixture；
(2) filter residue in the step (1) is added dehydrated alcohol and filters after being heated to reflux 20-40 minutes, obtains the second filtrate
And filter residue；
(3) filter residue obtained by the step (2) is rinsed with dehydrated alcohol, washing lotion is incorporated into the second filtrate, obtains third filtrate；
(4) the first filtrate that the step (1) obtains and the third filtrate that the step (3) obtains are merged, is spray-dried
It is spare to traditional Chinese medicine powder；
Step 3: weighing in dove stomach freeze-dried powder made from step 1 and dove golden freeze-dried powder respectively in parts by weight, and by itself and step
Traditional Chinese medicine powder made from rapid two is uniformly mixed, and obtains mixed raw material powder；
Step 4: mixed raw material powder that step 3 obtains is prepared using conventional drug tablet forming technique presently disclosed
A kind of drug for treating stomach trouble.
6. a kind of preparation method of drug for treating stomach trouble according to claim 5, which is characterized in that the step 1
In, the running parameter of microwave vacuum puffing drying process: pressure controls between -75~-80kPa, and microwave intensity is controlled 25
Between~30W/g, temperature is controlled between 65 DEG C~80 DEG C.
7. a kind of preparation method of drug for treating stomach trouble according to claim 5, which is characterized in that the step 2
In, the size controlling of traditional Chinese medicine powder is between 5~15 μm.
8. a kind of preparation method of drug for treating stomach trouble according to claim 5, which is characterized in that in the step 4
Tabletting specification be every tablet contain mixed raw material powder 0.3-0.5g.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112245537A (en) * | 2020-10-26 | 2021-01-22 | 郑州金鸽生物技术开发有限公司 | Composition for treating nephropathy and preparation method thereof |
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| CN106474418A (en) * | 2016-12-28 | 2017-03-08 | 陕西红顶名医堂药业有限公司 | For treating Chinese medicine composition of gastropathy and preparation method thereof |
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2018
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106474418A (en) * | 2016-12-28 | 2017-03-08 | 陕西红顶名医堂药业有限公司 | For treating Chinese medicine composition of gastropathy and preparation method thereof |
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| CN112245537A (en) * | 2020-10-26 | 2021-01-22 | 郑州金鸽生物技术开发有限公司 | Composition for treating nephropathy and preparation method thereof |
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Application publication date: 20190212 |