CN109316363A - A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation - Google Patents
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation Download PDFInfo
- Publication number
- CN109316363A CN109316363A CN201811494191.6A CN201811494191A CN109316363A CN 109316363 A CN109316363 A CN 109316363A CN 201811494191 A CN201811494191 A CN 201811494191A CN 109316363 A CN109316363 A CN 109316363A
- Authority
- CN
- China
- Prior art keywords
- parts
- fullerene
- moisturizing
- agent
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229910003472 fullerene Inorganic materials 0.000 title claims abstract description 107
- XMWRBQBLMFGWIX-UHFFFAOYSA-N C60 fullerene Chemical compound C12=C3C(C4=C56)=C7C8=C5C5=C9C%10=C6C6=C4C1=C1C4=C6C6=C%10C%10=C9C9=C%11C5=C8C5=C8C7=C3C3=C7C2=C1C1=C2C4=C6C4=C%10C6=C9C9=C%11C5=C5C8=C3C3=C7C1=C1C2=C4C6=C2C9=C5C3=C12 XMWRBQBLMFGWIX-UHFFFAOYSA-N 0.000 title claims abstract description 104
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 96
- 238000000034 method Methods 0.000 title claims abstract description 41
- 238000002360 preparation method Methods 0.000 title claims abstract description 38
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 115
- 239000000126 substance Substances 0.000 claims abstract description 69
- 229940069521 aloe extract Drugs 0.000 claims abstract description 37
- 238000005282 brightening Methods 0.000 claims abstract description 37
- 239000002671 adjuvant Substances 0.000 claims abstract description 36
- 230000002605 anti-dotal effect Effects 0.000 claims abstract description 30
- 239000000203 mixture Substances 0.000 claims abstract description 10
- 238000006243 chemical reaction Methods 0.000 claims description 94
- 239000007788 liquid Substances 0.000 claims description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- 150000001413 amino acids Chemical class 0.000 claims description 19
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 17
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 16
- CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims description 15
- 239000001540 sodium lactate Substances 0.000 claims description 15
- 229940005581 sodium lactate Drugs 0.000 claims description 15
- 235000011088 sodium lactate Nutrition 0.000 claims description 15
- 239000000463 material Substances 0.000 claims description 14
- -1 amino fullerene Chemical compound 0.000 claims description 12
- 239000000341 volatile oil Substances 0.000 claims description 9
- PWKNBLFSJAVFAB-UHFFFAOYSA-N 1-fluoro-2-nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1F PWKNBLFSJAVFAB-UHFFFAOYSA-N 0.000 claims description 8
- 241001116389 Aloe Species 0.000 claims description 8
- 239000009429 Ginkgo biloba extract Substances 0.000 claims description 8
- 229930189092 Notoginsenoside Natural products 0.000 claims description 8
- 102000019197 Superoxide Dismutase Human genes 0.000 claims description 8
- 108010012715 Superoxide dismutase Proteins 0.000 claims description 8
- LRTJRITVNJYMRV-UHFFFAOYSA-N [Se].S(O)(O)=O Chemical compound [Se].S(O)(O)=O LRTJRITVNJYMRV-UHFFFAOYSA-N 0.000 claims description 8
- 235000019169 all-trans-retinol Nutrition 0.000 claims description 8
- 239000011717 all-trans-retinol Substances 0.000 claims description 8
- 235000011399 aloe vera Nutrition 0.000 claims description 8
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 8
- 229940068052 ginkgo biloba extract Drugs 0.000 claims description 8
- 235000020686 ginkgo biloba extract Nutrition 0.000 claims description 8
- 235000012907 honey Nutrition 0.000 claims description 8
- SOQBVABWOPYFQZ-UHFFFAOYSA-N oxygen(2-);titanium(4+) Chemical compound [O-2].[O-2].[Ti+4] SOQBVABWOPYFQZ-UHFFFAOYSA-N 0.000 claims description 8
- 229920001296 polysiloxane Polymers 0.000 claims description 8
- 239000002904 solvent Substances 0.000 claims description 8
- 235000019485 Safflower oil Nutrition 0.000 claims description 7
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 7
- 239000003813 safflower oil Substances 0.000 claims description 7
- 235000005713 safflower oil Nutrition 0.000 claims description 7
- 229910052711 selenium Inorganic materials 0.000 claims description 7
- 239000011669 selenium Substances 0.000 claims description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 5
- 241000213006 Angelica dahurica Species 0.000 claims description 5
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 5
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims description 5
- 240000000851 Vaccinium corymbosum Species 0.000 claims description 5
- 235000003095 Vaccinium corymbosum Nutrition 0.000 claims description 5
- 235000017537 Vaccinium myrtillus Nutrition 0.000 claims description 5
- 235000021014 blueberries Nutrition 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 5
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims description 5
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims description 5
- 229940041616 menthol Drugs 0.000 claims description 5
- 235000019477 peppermint oil Nutrition 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 5
- XPCTZQVDEJYUGT-UHFFFAOYSA-N 3-hydroxy-2-methyl-4-pyrone Chemical compound CC=1OC=CC(=O)C=1O XPCTZQVDEJYUGT-UHFFFAOYSA-N 0.000 claims description 4
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims description 4
- 108010064851 Plant Proteins Proteins 0.000 claims description 4
- 239000003960 organic solvent Substances 0.000 claims description 4
- 235000021118 plant-derived protein Nutrition 0.000 claims description 4
- 229960001520 ranitidine hydrochloride Drugs 0.000 claims description 4
- GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 244000178870 Lavandula angustifolia Species 0.000 claims description 3
- 235000010663 Lavandula angustifolia Nutrition 0.000 claims description 3
- 235000019082 Osmanthus Nutrition 0.000 claims description 3
- 241000333181 Osmanthus Species 0.000 claims description 3
- 241000220317 Rosa Species 0.000 claims description 3
- 235000010208 anthocyanin Nutrition 0.000 claims description 3
- 239000004410 anthocyanin Substances 0.000 claims description 3
- 229930002877 anthocyanin Natural products 0.000 claims description 3
- 150000004636 anthocyanins Chemical class 0.000 claims description 3
- 239000001102 lavandula vera Substances 0.000 claims description 3
- 235000018219 lavender Nutrition 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 230000003068 static effect Effects 0.000 claims description 3
- 125000003184 C60 fullerene group Chemical group 0.000 claims description 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 2
- 239000004472 Lysine Substances 0.000 claims description 2
- HYMLWHLQFGRFIY-UHFFFAOYSA-N Maltol Natural products CC1OC=CC(=O)C1=O HYMLWHLQFGRFIY-UHFFFAOYSA-N 0.000 claims description 2
- 125000003916 ethylene diamine group Chemical group 0.000 claims description 2
- 229940043353 maltol Drugs 0.000 claims description 2
- 235000008390 olive oil Nutrition 0.000 claims description 2
- 239000004006 olive oil Substances 0.000 claims description 2
- 229920000642 polymer Polymers 0.000 claims description 2
- 238000003756 stirring Methods 0.000 claims description 2
- 235000001014 amino acid Nutrition 0.000 claims 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 claims 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 2
- NAQMVNRVTILPCV-UHFFFAOYSA-N hexane-1,6-diamine Chemical compound NCCCCCCN NAQMVNRVTILPCV-UHFFFAOYSA-N 0.000 claims 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims 1
- 239000004475 Arginine Substances 0.000 claims 1
- 241000196324 Embryophyta Species 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 235000004279 alanine Nutrition 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- GGHDAUPFEBTORZ-UHFFFAOYSA-N propane-1,1-diamine Chemical compound CCC(N)N GGHDAUPFEBTORZ-UHFFFAOYSA-N 0.000 claims 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 1
- 230000003712 anti-aging effect Effects 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 14
- 230000002087 whitening effect Effects 0.000 abstract description 8
- 239000002537 cosmetic Substances 0.000 abstract description 4
- 150000003254 radicals Chemical class 0.000 abstract description 4
- 231100000252 nontoxic Toxicity 0.000 abstract description 2
- 230000003000 nontoxic effect Effects 0.000 abstract description 2
- 230000001681 protective effect Effects 0.000 abstract description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical class [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 60
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 18
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 10
- 238000012360 testing method Methods 0.000 description 8
- 235000019441 ethanol Nutrition 0.000 description 7
- 229920005906 polyester polyol Polymers 0.000 description 6
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 6
- 239000000052 vinegar Substances 0.000 description 6
- 235000021419 vinegar Nutrition 0.000 description 6
- 235000017557 sodium bicarbonate Nutrition 0.000 description 5
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 5
- 206010020649 Hyperkeratosis Diseases 0.000 description 3
- 208000001126 Keratosis Diseases 0.000 description 3
- 230000036571 hydration Effects 0.000 description 3
- 238000006703 hydration reaction Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- WWMHTDYMDLGBCC-UHFFFAOYSA-N acetic acid;selenium Chemical compound [Se].CC(O)=O WWMHTDYMDLGBCC-UHFFFAOYSA-N 0.000 description 1
- 238000007259 addition reaction Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229930014669 anthocyanidin Natural products 0.000 description 1
- 150000001453 anthocyanidins Chemical class 0.000 description 1
- 235000008758 anthocyanidins Nutrition 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 229960004756 ethanol Drugs 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 235000004554 glutamine Nutrition 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012009 microbiological test Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001333 moisturizer Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 229960000620 ranitidine Drugs 0.000 description 1
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 238000010181 skin prick test Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 125000003944 tolyl group Chemical group 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Insects & Arthropods (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to cosmetic technical fields, and in particular to a method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation；The described composition with moisturizing, the skin conditioner of anti-senescence function are as follows: the modified soluble fullerene of 30-40 part of mass fraction meter, 10-15 parts of aloe extract, 6-10 parts of parts moisturizing water-retaining agent, 3-5 parts of auxiliary antidotal agent, 3-6 parts of brightening agent, 5-8 parts of adjuvant.Skin conditioner prepared by the present invention is prepared using modified aqueous fullerene, it makes use of Graphene derivatives can remove free radical, effective whitening on earth, moisturizing, anti-aging effect, furthermore itself be nontoxic substance, be a kind of environmentally protective product；Furthermore by the way that the substances such as aloe extract, moisturizing water-retaining agent, auxiliary antidotal agent, brightening agent, adjuvant are added, keep its effect more preferable than the simple effect using modified water-soluble fullerene, be that they reach trade-off effect.
Description
Technical field
The invention belongs to cosmetic technical fields, and in particular to a kind of to have moisturizing, anti-aging function using fullerene preparation
The method of the skin conditioner of energy.
Background technique
Fullerene is a kind of free radical high-efficiency scavenging agent and the substance with strong oxidation resistance.And the derivative of fullerene
With anti-aging, cytoprotection, antimicrobial, light power, the carrier band various actives such as drug and oncotherapy, in cosmetic art
Field plays an important role, its research in terms of cosmetics was achieved again compared with much progress in recent years.And human skin declines
The always phenomenon of a nature, but people always want to find it is a kind of can effective substance can slow down skin aging and
Effectively increase the whiteness of skin, however, the anti-aging nowadays used mostly, moisturizing, skin brightening drug or skin conditioner
Mostly be all it is poisonous and hazardous, skin can be caused serious injury, therefore, develop a safety and environmental protection, will not be to skin
The skin conditioner damaged just seems very important.
In view of the above problems, the present invention has developed the shield for having moisturizing, anti-senescence function using fullerene preparation
Skin agent can be good at meeting the needs of market is to skin moisture-keeping, anti-aging.
Summary of the invention
In order to achieve the purpose that in background technique, proposed by the present invention a kind of have moisturizing, anti-ageing using fullerene preparation
The method of the skin conditioner of old function；
What the present invention realized by the following technical solutions
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: the modified soluble fullerene, 10- of 30-40 part of mass fraction meter
15 parts of aloe extract, 6-10 parts of parts moisturizing water-retaining agent, 3-5 parts of auxiliary antidotal agent, 3-6 parts of brightening agent, 5-8 parts
Adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
The modified soluble fullerene of 30-40 parts of number meter, 10-15 parts of aloe extract, 6-10 parts of parts moisturizing water-retaining agent, 3-5
The auxiliary antidotal agent, 3-6 parts of brightening agent, 5-8 parts of adjuvant of part add in reaction kettle, carry out under the conditions of 50-60 DEG C anti-
It answers 2-3 hours, after fully reacting, obtained substance is cooled down, obtained substance is exactly with moisturizing, anti-senescence function
Skin conditioner.
Further, the modified soluble fullerene are as follows: by the aqueous fullerene, 6-8 of 50-60 part of mass fraction meter
Part polyester polyol, 3-5 part of citric acid, 1-2 parts the concentrated sulfuric acid addition reaction kettle in, under 60-70 DEG C of Conditions Condition into
Row reaction 10-12 hours after fully reacting, is added 2-4 parts of sodium bicarbonate, adjusts its pH value in 7-8, then take material
Out, which is exactly modified water-soluble fullerene.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 40-60 parts liquid is added in beaker, and 20-30 parts of dehydrated alcohol is then added into beaker, is stirred 3-5 minutes
Afterwards, by its it is 10-12 hours static after, be filtered removing filter residue, be then added into Rotary Evaporators and remove ethyl alcohol
Solvent, obtaining liquid substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by the wild peak wax of 10-15 part of mass fraction meter, 6-8 parts sweet
Oil, 3-6 parts of sorbierite, 1-2 parts of silicone, 3-5 parts of amino acid, 2-3 parts of sodium lactate are added in reaction kettle, in 50-60
Reaction 1-2 hours is carried out under DEG C Conditions Condition, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by the superoxide dismutase of 3-5 part of mass fraction meter, 1-2 parts
Acetic acid selenium, 3-5 parts of Alphalin, 5-8 parts sulfurous acid selenium be added reaction kettle in, carry out hybrid reaction obtain after twenty minutes
Substance, which is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 5-8 part pyrrolidone sodium carboxylate, 3-5 parts of the lactic acid of mass fraction meter
Sodium, 6-8 parts of ginkgo biloba extract, 1-2 parts of disodium terephthalate, 3-5 parts of nano-titanium dioxide are added in reaction kettle,
The substance obtained after carrying out reaction under the conditions of 40 DEG C 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by the ferine honey of 4-5 part of mass fraction meter, 4-6 parts of notoginsenoside,
3-5 parts of essential oil (e.g., rose ethereal oil, Lavender, osmanthus essential oil, olive oil, menthol, maltol), 1-3 parts red
Caul-fat is added in reaction kettle, and the substance obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C, which is exactly adjuvant.
Detailed description of the invention
The whitening effect figure of Fig. 1 fullerene anti-aging mechanism figure Fig. 2 skin conditioner
Beneficial to benefit
(1) skin conditioner prepared by the present invention is prepared using modified aqueous fullerene, and it makes use of modifications
Water-soluble fullerene can remove free radical, effectively whitening on earth, moisturizing, anti-aging effect, furthermore itself be nontoxic nothing
Harmful substance is a kind of environmentally protective product；
(2) present invention is by being added the objects such as aloe extract, moisturizing water-retaining agent, auxiliary antidotal agent, brightening agent, adjuvant
Matter, makes its effect than the simple effect using modified water-soluble fullerene at the effect of effectively improving skin conditioner prepared by the present invention
Fruit is more preferable, is that they reach trade-off effect.
(3) present invention is by being added blueberry anthocyanin, Angelica Dahurica extract, peppermint oil, glutamine, plant protein powder, salt
On the one hand sour ranitidine improves modified water-soluble so that it generates mutually synergistic effect between modified soluble fullerene
Property fullerene can remove the effect of free radical, and these components itself also function to whitening, moisturizing, anti-aging effect.
(4) water-soluble fullerene is made of to be keyed water-soluble amino acids, Er Qietong by chemistry on fullerene molecule
The water-soluble fullerene for crossing process preparation, can preferably merge with aloe extract, further increase removing freely
The ability of base, whitening, moisturizing, the effect of anti-aging are more preferable.
Specific embodiment
In order to keep the purpose of the present invention, technical scheme and beneficial effects clearer, below in conjunction with experimental data, to this
The preferred embodiment of invention is described in detail, to facilitate the technical staff to understand.
Embodiment 1
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: 40 parts of modified soluble fullerene of mass fraction meter, 15 parts
Aloe extract, 10 parts of parts moisturizing water-retaining agent, 5 parts of auxiliary antidotal agent, 6 parts of brightening agent, 8 parts of adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
40 parts of modified soluble fullerenes of number meter, 15 parts of aloe extract, the moisturizing water-retaining agent of 10 parts of parts, 5 parts of auxiliary are anti-
Aging agent, 6 parts of brightening agent, 8 parts of adjuvant add in reaction kettle, and reaction 3 hours, fully reacting are carried out under the conditions of 50 DEG C
Afterwards, obtained substance is cooled down, obtained substance is exactly the skin conditioner with moisturizing, anti-senescence function.
Further, the modified soluble fullerene are as follows: by 60 parts of aqueous fullerene of mass fraction meter, 8 parts
Polyester polyol, 5 parts of citric acid, 1 part of the concentrated sulfuric acid are added in reaction kettle, and it is small that reaction 10 is carried out under 60 DEG C of Conditions Conditions
When, after fully reacting, 2 parts of sodium bicarbonate is added, adjusts its pH value in 7-8, then takes out material, which is exactly to be modified
Aqueous fullerene.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 40 parts liquid is added in beaker, 20 parts of dehydrated alcohol is then added into beaker, after being stirred 3-5 minutes, by it
After static 10 hours, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent, obtains liquid
Body substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by 10 parts of mass fraction meter of wild peak wax, 6 parts of glycerol, 3 parts
Sorbierite, 1 part of silicone, 3 parts of amino acid, 2 parts of sodium lactate be added in reaction kettle, carried out under 50 DEG C of Conditions Conditions anti-
It answers 1 hour, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by 3 parts of superoxide dismutase of mass fraction meter, 1 part of vinegar
Sour selenium, 3 parts of Alphalin, 5 parts of sulfurous acid selenium are added in reaction kettle, the substance obtained after carrying out hybrid reaction 20 minutes,
The substance is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 5 parts of pyrrolidone sodium carboxylates of mass fraction meter, 3 parts of sodium lactate, 6 parts
Ginkgo biloba extract, 1 part of disodium terephthalate, 3 parts nano-titanium dioxide be added reaction kettle in, under the conditions of 40 DEG C into
The substance that row reaction obtains after 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by 4 parts of ferine honey of mass fraction meter, 4 parts of notoginsenoside, 3 parts
Rose ethereal oil, 1 part of safflower oil are added in reaction kettle, the object obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C
Matter, the substance are exactly adjuvant.
Embodiment 2
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: 30 parts of modified soluble fullerene of mass fraction meter, 10 parts
Aloe extract, 6 parts of parts moisturizing water-retaining agent, 3 parts of auxiliary antidotal agent, 3 parts of brightening agent, 5 parts of adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
30 parts of modified soluble fullerenes of number meter, 10 parts of aloe extract, the moisturizing water-retaining agent of 6 parts of parts, 3 parts of auxiliary are anti-ageing
Old agent, 3 parts of brightening agent, 5 parts of adjuvant add in reaction kettle, and reaction 2 hours is carried out under the conditions of 50 DEG C, after fully reacting,
Obtained substance is cooled down, obtained substance is exactly the skin conditioner with moisturizing, anti-senescence function.
Further, the modified soluble fullerene are as follows: by 50 parts of aqueous fullerene of mass fraction meter, 6 parts
Polyester polyol, 3 parts of citric acid, 1-2 parts of the concentrated sulfuric acid are added in reaction kettle, and it is small that reaction 10 is carried out under 60 DEG C of Conditions Conditions
When, after fully reacting, 2 parts of sodium bicarbonate is added, adjusts its pH value in 7-8, then takes out material, which is exactly to change
The aqueous fullerene of property.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 60 parts liquid is added in beaker, and 30 parts of dehydrated alcohol is then added into beaker, is stirred after five minutes, its is quiet
Only after 12 hours, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent, obtains liquid
Substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by 15 parts of mass fraction meter of wild peak wax, 8 parts of glycerol, 6 parts
Sorbierite, 2 parts of silicone, 5 parts of amino acid, 3 parts of sodium lactate be added in reaction kettle, carried out under 60 DEG C of Conditions Conditions anti-
It answers 2 hours, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by 5 parts of superoxide dismutase of mass fraction meter, 2 parts of vinegar
Sour selenium, 5 parts of Alphalin, 8 parts of sulfurous acid selenium are added in reaction kettle, the substance obtained after carrying out hybrid reaction 20 minutes,
The substance is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 8 parts of pyrrolidone sodium carboxylates of mass fraction meter, 5 parts of sodium lactate, 8 parts
Ginkgo biloba extract, 2 parts of disodium terephthalate, 5 parts nano-titanium dioxide be added reaction kettle in, under the conditions of 40 DEG C into
The substance that row reaction obtains after 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by 5 parts of ferine honey of mass fraction meter, 6 parts of notoginsenoside, 5 parts
Essential oil Lavender, 1 part of safflower oil are added in reaction kettle, obtain after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C
Substance, the substance are exactly adjuvant.
Embodiment 3
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: 35 parts of modified soluble fullerene of mass fraction meter, 15 parts
Aloe extract, 8 parts of parts moisturizing water-retaining agent, 3 parts of auxiliary antidotal agent, 4 parts of brightening agent, 8 parts of adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
35 parts of modified soluble fullerenes of number meter, 15 parts of aloe extract, the moisturizing water-retaining agent of 8 parts of parts, 3 parts of auxiliary are anti-ageing
Old agent, 4 parts of brightening agent, 8 parts of adjuvant add in reaction kettle, and reaction 2-3 hours is carried out under the conditions of 50-60 DEG C, has been reacted
Quan Hou cools down obtained substance, and obtained substance is exactly the skin conditioner with moisturizing, anti-senescence function.
Further, the modified soluble fullerene are as follows: by 55 parts of aqueous fullerene of mass fraction meter, 6 parts
Polyester polyol, 4 parts of citric acid, 2 parts of the concentrated sulfuric acid are added in reaction kettle, and it is small that reaction 10 is carried out under 65 DEG C of Conditions Conditions
When, after fully reacting, 3 parts of sodium bicarbonate is added, adjusts its pH value in 7-8, then takes out material, which is exactly to be modified
Aqueous fullerene.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 50 parts liquid is added in beaker, and 30 parts of dehydrated alcohol is then added into beaker, after being stirred 4 minutes, its is quiet
Only after 12 hours, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent, obtains liquid
Substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by 12 parts of mass fraction meter of wild peak wax, 8 parts of glycerol, 5 parts
Sorbierite, 1 part of silicone, 4 parts of amino acid, 3 parts of sodium lactate be added in reaction kettle, carried out under 50 DEG C of Conditions Conditions anti-
It answers 1 hour, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by 4 parts of superoxide dismutase of mass fraction meter, 1 part of vinegar
Sour selenium, 4 parts of Alphalin, 5 parts of sulfurous acid selenium are added in reaction kettle, the substance obtained after carrying out hybrid reaction 20 minutes,
The substance is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 6 parts of pyrrolidone sodium carboxylates of mass fraction meter, 5 parts of sodium lactate, 7 parts
Ginkgo biloba extract, 2 parts of disodium terephthalate, 4 parts nano-titanium dioxide be added reaction kettle in, under the conditions of 40 DEG C into
The substance that row reaction obtains after 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by 4 parts of ferine honey of mass fraction meter, 6 parts of notoginsenoside, 4 parts
Osmanthus essential oil, 1 part of safflower oil are added in reaction kettle, the substance obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C,
The substance is exactly adjuvant.
Embodiment 4
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: 40 parts of modified soluble fullerene of mass fraction meter, 12 parts
Aloe extract, 6 parts of parts moisturizing water-retaining agent, 4 parts of auxiliary antidotal agent, 6 parts of brightening agent, 6 parts of adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
40 parts of modified soluble fullerenes of number meter, 12 parts of aloe extract, the moisturizing water-retaining agent of 6 parts of parts, 4 parts of auxiliary are anti-ageing
Old agent, 6 parts of brightening agent, 6 parts of adjuvant add in reaction kettle, and reaction 2-3 hours is carried out under the conditions of 50-60 DEG C, has been reacted
Quan Hou cools down obtained substance, and obtained substance is exactly the skin conditioner with moisturizing, anti-senescence function.
Further, the modified soluble fullerene are as follows: by 60 parts of aqueous fullerene of mass fraction meter, 7 parts
Polyester polyol, 5 parts of citric acid, 1 part of the concentrated sulfuric acid are added in reaction kettle, and it is small that reaction 10 is carried out under 70 DEG C of Conditions Conditions
When, after fully reacting, 4 parts of sodium bicarbonate is added, adjusts its pH value in 7-8, then takes out material, which is exactly to be modified
Aqueous fullerene.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 50 parts liquid is added in beaker, and 30 parts of dehydrated alcohol is then added into beaker, after being stirred 3 minutes, its is quiet
Only after 10 hours, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent, obtains liquid
Substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by 10 parts of mass fraction meter of wild peak wax, 7 parts of glycerol, 3 parts
Sorbierite, 1 part of silicone, 4 parts of amino acid, 2 parts of sodium lactate be added in reaction kettle, carried out under 60 DEG C of Conditions Conditions anti-
It answers 1 hour, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by 3 parts of superoxide dismutase of mass fraction meter, 1 part of vinegar
Sour selenium, 4 parts of Alphalin, 6 parts of sulfurous acid selenium are added in reaction kettle, the substance obtained after carrying out hybrid reaction 20 minutes,
The substance is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 5 parts of pyrrolidone sodium carboxylates of mass fraction meter, 4 parts of sodium lactate, 6 parts
Ginkgo biloba extract, 2 parts of disodium terephthalate, 4 parts nano-titanium dioxide be added reaction kettle in, under the conditions of 40 DEG C into
The substance that row reaction obtains after 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by 5 parts of ferine honey of mass fraction meter, 5 parts of notoginsenoside, 3 parts
Menthol, 2 parts of safflower oil are added in reaction kettle, and the substance obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C should
Substance is exactly adjuvant.
Embodiment 5
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: 40 parts of modified soluble fullerene of mass fraction meter, 12 parts
Aloe extract, 6 parts of parts moisturizing water-retaining agent, 4 parts of auxiliary antidotal agent, 6 parts of brightening agent, 6 parts of adjuvant, blueberry
2 parts of anthocyanidin, 1 part of Angelica Dahurica extract, 0.5 part of peppermint oil, 10 parts of glutamine, 15 parts of plant protein powder, ranitidine hydrochloride
5 parts；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
40 parts of modified soluble fullerenes of number meter, 12 parts of aloe extract, the moisturizing water-retaining agent of 6 parts of parts, 4 parts of auxiliary are anti-ageing
Old agent, 6 parts of brightening agent, 6 parts of adjuvant add in reaction kettle, and reaction 2-3 hours is carried out under the conditions of 50-60 DEG C, has been reacted
Quan Hou cools down obtained substance；Then 2 parts of blueberry anthocyanin, 1 part of Angelica Dahurica extract, 0.5 part of peppermint oil, paddy is added
Then 10 parts of glutamine, 15 parts of plant protein powder, 5 parts of ranitidine hydrochloride, stirring adjust pH value to neutral, obtained substance
It is exactly the skin conditioner with moisturizing, anti-senescence function.
Further, the modified soluble fullerene are as follows: by 60 parts of aqueous fullerene of mass fraction meter, 7 parts
Polyester polyol, 5 parts of citric acid, 1 part of the concentrated sulfuric acid are added in reaction kettle, and it is small that reaction 10 is carried out under 70 DEG C of Conditions Conditions
When, after fully reacting, 4 parts of sodium bicarbonate is added, adjusts its pH value in 7-8, then takes out material, which is exactly to be modified
Aqueous fullerene.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 50 parts liquid is added in beaker, and 30 parts of dehydrated alcohol is then added into beaker, after being stirred 3 minutes, its is quiet
Only after 10 hours, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent, obtains liquid
Substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by 10 parts of mass fraction meter of wild peak wax, 7 parts of glycerol, 3 parts
Sorbierite, 1 part of silicone, 4 parts of amino acid, 2 parts of sodium lactate be added in reaction kettle, carried out under 60 DEG C of Conditions Conditions anti-
It answers 1 hour, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by 3 parts of superoxide dismutase of mass fraction meter, 1 part of vinegar
Sour selenium, 4 parts of Alphalin, 6 parts of sulfurous acid selenium are added in reaction kettle, the substance obtained after carrying out hybrid reaction 20 minutes,
The substance is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 5 parts of pyrrolidone sodium carboxylates of mass fraction meter, 4 parts of sodium lactate, 6 parts
Ginkgo biloba extract, 2 parts of disodium terephthalate, 4 parts nano-titanium dioxide be added reaction kettle in, under the conditions of 40 DEG C into
The substance that row reaction obtains after 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by 5 parts of ferine honey of mass fraction meter, 5 parts of notoginsenoside, 3 parts
Menthol, 2 parts of safflower oil are added in reaction kettle, and the substance obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C should
Substance is exactly adjuvant.
Embodiment 6
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation:
A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation, which is characterized in that described
Composition with moisturizing, the skin conditioner of anti-senescence function are as follows: 40 parts of modified soluble fullerene of mass fraction meter, 12 parts
Aloe extract, 6 parts of parts moisturizing water-retaining agent, 4 parts of auxiliary antidotal agent, 6 parts of brightening agent, 6 parts of adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass parts
40 parts of modified soluble fullerenes of number meter, 12 parts of aloe extract, the moisturizing water-retaining agent of 6 parts of parts, 4 parts of auxiliary are anti-ageing
Old agent, 6 parts of brightening agent, 6 parts of adjuvant add in reaction kettle, and reaction 2-3 hours is carried out under the conditions of 50-60 DEG C, has been reacted
Quan Hou cools down obtained substance, and obtained substance is exactly the skin conditioner with moisturizing, anti-senescence function.
Further, which is made of to be keyed water-soluble amino acids by chemistry on fullerene molecule,
The mass ratio of water-soluble amino acids and fullerene is 0.5:1, and the fullerene is C60Fullerene, the water-soluble amino acids are
Lysine, wherein the following steps are included: 1) mixing aminating agent 30mL and sodium hydroxide 2g, after mixing evenly, be added dropwise
Organic solution 50mL containing fullerene is added in reaction kettle, reaction 12 hours is carried out under the conditions of 60 DEG C, then at 60 DEG C
Under, it is dried in vacuo 72h, obtains amino fullerene；The aminating agent is ethylenediamine；The organic solution containing fullerene
It is made of fullerene and organic solvent, 1mg containing fullerene in the organic solution of every 1mL；The organic solvent is toluene；2)
It weighs and is uniformly mixed in amino fullerene 20mg obtained above and water-soluble amino acids 50mg, 40mL formamide, reaction is added
In kettle, reaction 12 hours is carried out under 60 DEG C of Conditions Conditions, then at 60 DEG C, is dried in vacuo 72h, is obtained fullerene-water solubility
Amino acid polymer, i.e. water-soluble fullerene.
Further, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then be weighed
The 50 parts liquid is added in beaker, and 30 parts of dehydrated alcohol is then added into beaker, after being stirred 3 minutes, its is quiet
Only after 10 hours, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent, obtains liquid
Substance is exactly aloe extract.
Further, the moisturizing water-retaining agent are as follows: by 10 parts of mass fraction meter of wild peak wax, 7 parts of glycerol, 3 parts
Sorbierite, 1 part of silicone, 4 parts of amino acid, 2 parts of sodium lactate be added in reaction kettle, carried out under 60 DEG C of Conditions Conditions anti-
It answers 1 hour, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
Further, the auxiliary antidotal agent are as follows: by 3 parts of superoxide dismutase of mass fraction meter, 1 part of vinegar
Sour selenium, 4 parts of Alphalin, 6 parts of sulfurous acid selenium are added in reaction kettle, the substance obtained after carrying out hybrid reaction 20 minutes,
The substance is exactly to assist antidotal agent.
Further, the brightening agent are as follows: by 5 parts of pyrrolidone sodium carboxylates of mass fraction meter, 4 parts of sodium lactate, 6 parts
Ginkgo biloba extract, 2 parts of disodium terephthalate, 4 parts nano-titanium dioxide be added reaction kettle in, under the conditions of 40 DEG C into
The substance that row reaction obtains after 1 hour, which is exactly brightening agent.
Further, the adjuvant are as follows: by 5 parts of ferine honey of mass fraction meter, 5 parts of notoginsenoside, 3 parts
Menthol, 2 parts of safflower oil are added in reaction kettle, and the substance obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C should
Substance is exactly adjuvant.
Test 1: the test of keratoderma hydration rate: working principle is using capacitor as instrument probe, since water is skin
The upper maximum substance of dielectric constant, when skin moisture content changes, the capacitance of skin also changes, it is possible to
By measuring skin pricktest capacitance, analyzing skin surface moisture content.Instrument used is Corneometer CM825.Pass through survey
Amount measures the variation of water content of stratum corneum using the variation of keratoderma capacitance before and after product, thus anti-to evaluate whitening
Such method of the moisture-keeping efficacy of aging skin conditioner carries out quantification to the moisture content of keratoderma, can delicately react skin
The variation of skin moisture content, and favorable reproducibility are one of current common methods of whitening anti-aging skin conditioner efficacy assessments.
Experimental method: side is bent in candidate or so forearm and marks 3 × 3cm2The square Experimental Area of size, is made with left arm
For the test zone of moisturizer, uniform skin conditioner 0.1g every square centimeter, the corresponding symmetrical region of right arm is blank control, then
The moisture content that each experiment position is detected with Corneometer CM825 test, is repeated 5 times respectively, obtains average value.Use formula
(1) calculated hydration rate.
Hydration rate=(test value-blank value)/blank value × 100% formula (1)
The detection of moistening effect, the results are shown in Table 1:
| Time | 1 hour | 5 hours | 10 hours |
| Embodiment 1 | 95 | 70 | 60 |
| Embodiment 2 | 98 | 71 | 62 |
| Embodiment 3 | 92 | 68 | 59 |
| Embodiment 4 | 94 | 69 | 60 |
| Embodiment 5 | 101 | 80 | 71 |
| Embodiment 6 | 102 | 81 | 72 |
From the above results, the embodiment of the present application achieves good moistening effect, and the guarantor of embodiment 5-6
Wet effect is substantially better than embodiment 1-4.
Test case 2 [0058] carries out whitening anti-aging skin conditioner made from embodiment 1-7 with dark brown vial respectively
It is filling, bottle cap is opened wide, is placed under 40 DEG C of environment temperature, 85% environment of relative humidity preservation 90 days, then carries out golden yellow grape
Coccus (ATCC 6538) total plate count test, referring to GBT 4789.2-2008 microbiological test of food hygiene total plate count
Measurement.Specific test result is shown in Table 2.
| S. aureus colonies sum, cfu/g | |
| Embodiment 1 | 382 |
| Embodiment 2 | 365 |
| Embodiment 3 | 421 |
| Embodiment 4 | 396 |
| Embodiment 5 | 292 |
| Embodiment 6 | 289 |
From the above results, the embodiment of the present application achieves good anti-corrosion effect, and the anti-corrosion of embodiment 5-6
Effect is substantially better than embodiment 1-4.
Finally, it is stated that preferred embodiment above is only used to illustrate the technical scheme of the present invention rather than limits, although logical
It crosses above preferred embodiment the present invention is described in detail, however, those skilled in the art should understand that, can be
Various changes are made to it in form and in details, without departing from defined by claims of the present invention.
Claims (8)
1. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function, which is characterized in that the tool
It is made of the skin conditioner of moisturizing, anti-senescence function are as follows: the modified soluble fullerene, 10-15 of 30-40 part of mass fraction meter
Part aloe extract, 6-10 part parts moisturizing water-retaining agent, 3-5 parts assist antidotal agent, 3-6 parts of brightening agent, 5-8 parts
Adjuvant；
A kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function are as follows: by mass fraction meter
The modified soluble fullerene of 30-40 part, 10-15 parts of aloe extract, the moisturizing water-retaining agent of 6-10 parts of parts, 3-5 parts
Auxiliary antidotal agent, 3-6 parts of brightening agent, 5-8 parts of adjuvant add in reaction kettle, and reaction 2-3 is carried out under the conditions of 50-60 DEG C
Hour, after fully reacting, obtained substance is cooled down, obtained substance is exactly the skin care with moisturizing, anti-senescence function
Agent.
2. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It further include 1-2 parts of blueberry anthocyanin, 0.5-1 parts of Angelica Dahurica extract, 0.1-0.5 parts of peppermint oil, 5-10 parts of glutamine, plant egg
5-15 parts of white powder, 1-5 parts of ranitidine hydrochloride；A kind of shield using fullerene preparation with moisturizing, anti-senescence function
The method of skin agent are as follows: by modified soluble fullerene, 10-15 parts of the aloe extract, 6-10 of 30-40 part of mass fraction meter
Part moisturizing water-retaining agent of part, 3-5 parts of auxiliary antidotal agent, 3-6 parts of brightening agent, 5-8 parts of adjuvant add in reaction kettle,
Reaction 2-3 hours is carried out under the conditions of 50-60 DEG C, and after fully reacting, obtained substance is cooled down；Then blueberry flower is added
Green 1-2 parts of element, 0.5-1 parts of Angelica Dahurica extract, 0.1-0.5 parts of peppermint oil, 5-10 parts of glutamine, 5-15 parts of plant protein powder,
1-5 parts of ranitidine hydrochloride, then stirring adjusts pH value to neutrality, obtained substance is exactly with moisturizing, anti-senescence function
Skin conditioner.
3. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It is characterized in that, the modified soluble fullerene are as follows: the water-soluble fullerene is to pass through chemical bond on fullerene molecule
Connection water-soluble amino acids are made, and the mass ratio of water-soluble amino acids and fullerene is 0.3-0.5:1, and the fullerene is C60
Fullerene, the water-soluble amino acids be alanine, glycine, serine, arginine, lysine and tianmenine at least
It is a kind of, wherein the following steps are included: 1) mix aminating agent 10-30mL and sodium hydroxide 0.5-2g, after mixing evenly, by
It is added dropwise to the organic solution 50mL containing fullerene, is added in reaction kettle, reaction 10-12 is carried out under 60-70 DEG C of Conditions Condition
Hour, then at 20-60 DEG C, it is dried in vacuo 24-72h, obtains amino fullerene；The aminating agent is ethylenediamine, 1,3-
One of propane diamine, 1,6- hexamethylene diamine；The organic solution containing fullerene is made of fullerene and organic solvent, often
1mg containing fullerene in the organic solution of 1mL；The organic solvent is one or more of toluene, benzene, tetrahydrofuran
Mixture；2) amino fullerene 10-20mg obtained above and water-soluble amino acids 40-50mg, 20-40mL formamide are weighed
In be uniformly mixed, be added reaction kettle in, carried out under 60-70 DEG C of Conditions Condition reaction 10-12 hours, then at 20-60 DEG C,
It is dried in vacuo 24-72h, obtains fullerene-water soluble amino acid polymer, i.e. water-soluble fullerene.
4. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It is characterized in that, the aloe extract are as follows: crushed to obtain sticky liquid for the aloe of collection, then weigh 40-
The 60 parts liquid is added in beaker, and 20-30 parts of dehydrated alcohol is then added into beaker, will after being stirred 3-5 minutes
After its is 10-12 hours static, it is filtered removing filter residue, is then added into Rotary Evaporators and removes alcohol solvent,
Obtaining liquid substance is exactly aloe extract.
5. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It is characterized in that, the moisturizing water-retaining agent are as follows: by wild peak wax, 6-8 parts of the glycerol, 3-6 of 10-15 part of mass fraction meter
The sorbierite, 1-2 parts of silicone, 3-5 parts of amino acid, 2-3 parts of sodium lactate of part are added in reaction kettle, in 50-60 DEG C of condition
Under the conditions of carry out reaction 1-2 hours, after fully reacting, material is taken out, which is exactly moisturizing water-retaining agent.
6. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It is characterized in that, the auxiliary antidotal agent are as follows: by the superoxide dismutase, 1-2 parts of acetic acid of 3-5 part of mass fraction meter
Selenium, 3-5 parts of Alphalin, 5-8 parts of sulfurous acid selenium are added in reaction kettle, carry out the substance that hybrid reaction obtains after twenty minutes,
The substance is exactly to assist antidotal agent.
7. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It is characterized in that, the brightening agent are as follows: by 5-8 part pyrrolidone sodium carboxylate, 3-5 parts of the sodium lactate, 6-8 of mass fraction meter
The ginkgo biloba extract, 1-2 parts of disodium terephthalate, 3-5 parts of nano-titanium dioxide of part are added in reaction kettle, in 40 DEG C of items
The substance obtained after carrying out reaction under part 1 hour, which is exactly brightening agent.
8. a kind of method using fullerene preparation with moisturizing, the skin conditioner of anti-senescence function according to claim 1,
It is characterized in that, the adjuvant are as follows: by the ferine honey of 4-5 part of mass fraction meter, 4-6 parts of notoginsenoside, 3-5 parts
Essential oil (e.g., rose ethereal oil, Lavender, osmanthus essential oil, olive oil, menthol, maltol), 1-3 parts of safflower oil
It is added in reaction kettle, the substance obtained after carrying out hybrid reaction 45 minutes under the conditions of 30 DEG C, which is exactly adjuvant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811494191.6A CN109316363A (en) | 2018-12-07 | 2018-12-07 | A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811494191.6A CN109316363A (en) | 2018-12-07 | 2018-12-07 | A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109316363A true CN109316363A (en) | 2019-02-12 |
Family
ID=65257107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811494191.6A Pending CN109316363A (en) | 2018-12-07 | 2018-12-07 | A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109316363A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109984948A (en) * | 2019-03-14 | 2019-07-09 | 广州珈源日化用品有限公司 | One kind containing fullerene, haematococcus pluvialis and the anti-ageing Essence of olea europaea fruit extract |
| CN110169937A (en) * | 2019-06-06 | 2019-08-27 | 齐向民 | A kind of fullerene type whitening skin-protection cream |
| CN110192985A (en) * | 2019-06-26 | 2019-09-03 | 广州市百爱神生物科技有限公司 | A kind of care agent and preparation method thereof for skin moisture-keeping reparation |
| CN113208935A (en) * | 2021-05-26 | 2021-08-06 | 正定仁运诚医药科技有限责任公司 | Cosmetic containing fullerene derivative |
| CN115252521A (en) * | 2022-08-09 | 2022-11-01 | 健而阳(深圳)科技有限公司 | Wrinkle-removing moisturizing eye essence and preparation method thereof |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102898542A (en) * | 2012-10-23 | 2013-01-30 | 郑州大学 | Water-soluble fullerene and application thereof |
| CN105434182A (en) * | 2015-12-23 | 2016-03-30 | 豌豆之本(北京)科技有限公司 | Fullerene composition applied to daily chemicals |
| CN106236674A (en) * | 2016-09-22 | 2016-12-21 | 上海新高姿化妆品有限公司 | A kind of compositions with white-skinned face function and the application in cosmetics thereof |
| CN106821843A (en) * | 2017-01-18 | 2017-06-13 | 安婕妤化妆品科技股份有限公司 | A kind of anti-apolexis composition containing close Luo Mu extracts and preparation method thereof |
| CN107049827A (en) * | 2017-05-02 | 2017-08-18 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of anti-wrinkle eye cream |
| CN107224416A (en) * | 2017-06-09 | 2017-10-03 | 佛山市汇汾化妆品科技有限公司 | A kind of anti-oxidant face mask |
| CN107898689A (en) * | 2017-12-05 | 2018-04-13 | 佛山微赢电子商务有限公司 | A kind of the painting type water laser accunputure and preparation method of zero addition |
| CN108670938A (en) * | 2018-08-07 | 2018-10-19 | 广州市名宇化妆品制造有限公司 | A kind of removing wrinkle and resisting aging essence object and preparation method thereof |
| CN108721197A (en) * | 2018-08-17 | 2018-11-02 | 广东丸美生物技术股份有限公司 | It is a kind of that there is composition and its application for improving skin pore and long-acting moisture-keeping efficacy |
| CN108743415A (en) * | 2018-06-14 | 2018-11-06 | 广州宝莱生物科技有限公司 | A kind of fullerene cleansing skin care product and using method thereof |
| CN108904408A (en) * | 2018-08-16 | 2018-11-30 | 余荣华 | A kind of formula of anti-wrinkle product |
-
2018
- 2018-12-07 CN CN201811494191.6A patent/CN109316363A/en active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102898542A (en) * | 2012-10-23 | 2013-01-30 | 郑州大学 | Water-soluble fullerene and application thereof |
| CN105434182A (en) * | 2015-12-23 | 2016-03-30 | 豌豆之本(北京)科技有限公司 | Fullerene composition applied to daily chemicals |
| CN106236674A (en) * | 2016-09-22 | 2016-12-21 | 上海新高姿化妆品有限公司 | A kind of compositions with white-skinned face function and the application in cosmetics thereof |
| CN106821843A (en) * | 2017-01-18 | 2017-06-13 | 安婕妤化妆品科技股份有限公司 | A kind of anti-apolexis composition containing close Luo Mu extracts and preparation method thereof |
| CN107049827A (en) * | 2017-05-02 | 2017-08-18 | 广州市聚吉科绿色化学共性技术研究院有限公司 | A kind of anti-wrinkle eye cream |
| CN107224416A (en) * | 2017-06-09 | 2017-10-03 | 佛山市汇汾化妆品科技有限公司 | A kind of anti-oxidant face mask |
| CN107898689A (en) * | 2017-12-05 | 2018-04-13 | 佛山微赢电子商务有限公司 | A kind of the painting type water laser accunputure and preparation method of zero addition |
| CN108743415A (en) * | 2018-06-14 | 2018-11-06 | 广州宝莱生物科技有限公司 | A kind of fullerene cleansing skin care product and using method thereof |
| CN108670938A (en) * | 2018-08-07 | 2018-10-19 | 广州市名宇化妆品制造有限公司 | A kind of removing wrinkle and resisting aging essence object and preparation method thereof |
| CN108904408A (en) * | 2018-08-16 | 2018-11-30 | 余荣华 | A kind of formula of anti-wrinkle product |
| CN108721197A (en) * | 2018-08-17 | 2018-11-02 | 广东丸美生物技术股份有限公司 | It is a kind of that there is composition and its application for improving skin pore and long-acting moisture-keeping efficacy |
Non-Patent Citations (1)
| Title |
|---|
| 石赟: "《5分钟护肤》", 30 November 2007, 河北科学技术出版社 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109984948A (en) * | 2019-03-14 | 2019-07-09 | 广州珈源日化用品有限公司 | One kind containing fullerene, haematococcus pluvialis and the anti-ageing Essence of olea europaea fruit extract |
| CN110169937A (en) * | 2019-06-06 | 2019-08-27 | 齐向民 | A kind of fullerene type whitening skin-protection cream |
| CN110192985A (en) * | 2019-06-26 | 2019-09-03 | 广州市百爱神生物科技有限公司 | A kind of care agent and preparation method thereof for skin moisture-keeping reparation |
| CN113208935A (en) * | 2021-05-26 | 2021-08-06 | 正定仁运诚医药科技有限责任公司 | Cosmetic containing fullerene derivative |
| CN115252521A (en) * | 2022-08-09 | 2022-11-01 | 健而阳(深圳)科技有限公司 | Wrinkle-removing moisturizing eye essence and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109316363A (en) | A method of there is the skin conditioner of moisturizing, anti-senescence function using fullerene preparation | |
| JP2003026560A (en) | Activated oxygen-eliminating agent, skin cosmetic material for preventing aging, and method for stabilizing activated oxygen-eliminating activity | |
| JP2006045181A (en) | External composition for skin | |
| CN109394565A (en) | A kind of moisturizing remediation composition and its application | |
| JP4831849B2 (en) | Active oxygen scavenger and its use | |
| CN107501422A (en) | Phellinus polyoses extract and its preparation method and application, the skin preparations for extenal use containing it | |
| CN109464308B (en) | Essential oil composition with blue light resisting and skin caring effects and application thereof | |
| KR20210041251A (en) | Cosmetic composition for scalp comprising Alpinia galanga(L) extract and functional plant extracts | |
| Mamillapalli et al. | Formulation, phytochemical, physical, biological evaluation of polyherbal vanishing cream, and facewash | |
| CN110141541A (en) | A kind of anti-dandruff and itching-relieving scalp conditioning liquid and its preparation method and application | |
| CN110236974A (en) | A kind of toner and preparation method thereof containing glycine betaine salicylic acid ionic liquid | |
| CN114259415A (en) | Acid-transmitting skin-refreshing and repairing facial mask | |
| JP2006225286A (en) | Dpph(1,1-diphenyl-2-picrylhydrazyl) radical scavenger, sod(superoxide dismutase) activity-like agent, skin-brightening preparation, l-dopa(l-2,3-dihydroxyphenylalanine) autoxidation inhibitor, collagenase activity inhibitor | |
| KR20100077693A (en) | Cosmetic composition comprising glyceryl caprylate and the extract from citrus grapefruit seed, bambusa vulgaris and pinus palustris leaf as preservatives | |
| CN111840157A (en) | Camellia flower compound composition | |
| CN109381375B (en) | Essential oil composition for scalp care and application | |
| KR20180082053A (en) | Cosmetic composition comprising bertholletia excelsa seed oil, plukenetia volubilis seed oil, mangifera indica extract and fragaria chiloensis extract | |
| CN110075029A (en) | A kind of painting type green plum anti-oxidant face mask and preparation method thereof | |
| WO2019024431A1 (en) | Chemical additive-free, natural, edible and palatable cosmetics product | |
| KR102386801B1 (en) | Cosmetic composition for skin improvement containing phyto DNA extracted from aloe vera adventitious root | |
| CN108078810A (en) | The skin care cosmetic composition of Whitening, spot | |
| CN110742833B (en) | Acne-removing, whitening and anti-aging essential oil composition as well as preparation method and application thereof | |
| KR101618595B1 (en) | Immature tomato hydrolysates that have high tomatidine content, preparation method thereof and cosmetic composition containing the same | |
| MX2011006747A (en) | Cosmetic composition containing a locust bean gum hydrolysate. | |
| JP5802930B2 (en) | Irritation relieving agent and hypoallergenic skin external preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190212 |